propranolol has been researched along with Amnesia in 20 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of migraine-associated ischemic stroke causing amnesia, wherein treatment with propranolol may have been contributory." | 7.69 | Migrainous stroke causing thalamic infarction and amnesia during treatment with propranolol. ( Greiner, F; Hamilton, WJ; Mendizabal, JE; Rothrock, JF, 1997) |
| "Post-trial injections of norepinephrine (NE) or cycloheximide (CHX) into the amygdala produces a long-term retention deficity (amnesia) for a 1-trial footshock experience in rats." | 7.66 | Amnesia attenuation specificity: propranolol reverses norepinephrine but not cycloheximide-induced amnesia. ( Berman, RF; Ellis, ME; Kesner, RP, 1983) |
| "With the ultimate goal of investigating boundary conditions for post-reactivation amnesia, we set out to replicate studies in which systemic, post-reactivation administration of midazolam, propranolol, or cycloheximide resulted in amnesia for contextual fear memories." | 3.91 | Limited replicability of drug-induced amnesia after contextual fear memory retrieval in rats. ( Alfei, JM; Beckers, T; Luyten, L; Schnell, AE; Schroyens, N, 2019) |
| "We report a case of migraine-associated ischemic stroke causing amnesia, wherein treatment with propranolol may have been contributory." | 3.69 | Migrainous stroke causing thalamic infarction and amnesia during treatment with propranolol. ( Greiner, F; Hamilton, WJ; Mendizabal, JE; Rothrock, JF, 1997) |
| "Bitemporal injections of puromycin that primarily affect the hippocampal-entorhinal area induce amnesia of aversive maze-learning in mice for 3 days after training but are ineffective 6 or more days after training." | 3.67 | Blockade of beta 1- but not of beta 2-adrenergic receptors replicates propranolol's suppression of the cerebral spread of an engram in mice. ( Brunswick, DJ; Church, AC; Flexner, JB; Flexner, LB; Rainbow, TC, 1985) |
| "Post-trial injections of norepinephrine (NE) or cycloheximide (CHX) into the amygdala produces a long-term retention deficity (amnesia) for a 1-trial footshock experience in rats." | 3.66 | Amnesia attenuation specificity: propranolol reverses norepinephrine but not cycloheximide-induced amnesia. ( Berman, RF; Ellis, ME; Kesner, RP, 1983) |
| "Due to the complex nature of Alzheimer's disease, multi-target-directed ligand approaches are one of the most promising strategies in the search for effective treatments." | 1.42 | Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo. ( Bajda, M; Brus, B; Czerwińska, P; Filipek, B; Gobec, S; Malawska, B; Sałat, K; Więckowska, A; Więckowski, K, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (45.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 7 (35.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Więckowska, A | 1 |
| Więckowski, K | 1 |
| Bajda, M | 1 |
| Brus, B | 1 |
| Sałat, K | 1 |
| Czerwińska, P | 1 |
| Gobec, S | 1 |
| Filipek, B | 1 |
| Malawska, B | 1 |
| Schroyens, N | 1 |
| Alfei, JM | 1 |
| Schnell, AE | 1 |
| Luyten, L | 1 |
| Beckers, T | 1 |
| Kindt, M | 3 |
| Soeter, M | 2 |
| Elsey, JWB | 1 |
| Van Ast, VA | 1 |
| Lee, JL | 1 |
| Everitt, BJ | 1 |
| Robinson, MJ | 1 |
| Franklin, KB | 1 |
| Menzies, RP | 1 |
| Bollók, I | 1 |
| Vécsei, L | 1 |
| Telegdy, G | 2 |
| Brown, MW | 1 |
| Rose, D | 1 |
| Ahlquist, J | 1 |
| Ellis, ME | 1 |
| Berman, RF | 1 |
| Kesner, RP | 1 |
| Sternberg, DB | 1 |
| Gold, PE | 1 |
| Mendizabal, JE | 1 |
| Greiner, F | 1 |
| Hamilton, WJ | 1 |
| Rothrock, JF | 1 |
| Jeffrey, PL | 1 |
| Fisher, CM | 1 |
| Bidzseranova, A | 1 |
| Penke, B | 1 |
| Tóth, G | 1 |
| Flexner, JB | 1 |
| Flexner, LB | 1 |
| Church, AC | 1 |
| Rainbow, TC | 1 |
| Brunswick, DJ | 1 |
| Izquierdo, I | 1 |
| McGaugh, JL | 1 |
| Zanotti, A | 1 |
| Valzelli, L | 1 |
| Toffano, G | 1 |
| Leonard, BE | 1 |
| Rigter, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD[NCT04468360] | Phase 2 | 256 participants (Anticipated) | Interventional | 2022-03-04 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propranolol and Amnesia
| Article | Year |
|---|---|
Human memory reconsolidation: A guiding framework and critical review of the evidence.
Topics: Amnesia; Animals; Electroshock; Emotional Intelligence; Humans; Memory; Memory Consolidation; Models | 2018 |
1 trial available for propranolol and Amnesia
| Article | Year |
|---|---|
Propranolol, traumatic memories, and amnesia: a study of 36 cases.
Topics: Adult; Amnesia; Delayed-Action Preparations; Female; Humans; Male; Memory; Propranolol; Stress Disor | 2012 |
18 other studies available for propranolol and Amnesia
| Article | Year |
|---|---|
Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo.
Topics: Acetylcholinesterase; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Blood-Brain Barrie | 2015 |
Limited replicability of drug-induced amnesia after contextual fear memory retrieval in rats.
Topics: Amnesia; Animals; Conditioning, Psychological; Fear; Hypnotics and Sedatives; Mental Recall; Midazol | 2019 |
Pharmacologically induced amnesia for learned fear is time and sleep dependent.
Topics: Amnesia; Blood-Brain Barrier; Brain; Conditioning, Psychological; Fear; Female; Humans; Learning; Ma | 2018 |
An Abrupt Transformation of Phobic Behavior After a Post-Retrieval Amnesic Agent.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Amnesia; Avoidance Learning; Choice Behavior; Double | 2015 |
Reactivation-dependent amnesia in Pavlovian approach and instrumental transfer.
Topics: Adrenergic beta-Antagonists; Amnesia; Animals; Appetitive Behavior; Brain; Conditioning, Classical; | 2008 |
Reconsolidation of a morphine place preference: impact of the strength and age of memory on disruption by propranolol and midazolam.
Topics: Amnesia; Animals; Choice Behavior; Conditioning, Psychological; Drug Synergism; Male; Memory; Midazo | 2010 |
The effects of interaction between propranolol and somatostatin on the active avoidance behavior, open-field activity and electroconvulsive shock-induced amnesia of rats.
Topics: Amnesia; Animals; Avoidance Learning; Behavior, Animal; Drug Interactions; Electroshock; Humans; Inj | 1983 |
Amnesia-producing drugs affect hippocampal frequency potentiation.
Topics: Amnesia; Animals; Evoked Potentials; Hippocampus; Humans; Lorazepam; Propranolol; Rats; Scopolamine | 1983 |
Amnesia attenuation specificity: propranolol reverses norepinephrine but not cycloheximide-induced amnesia.
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Cycloheximide; Drug Interactions; Humans; | 1983 |
Retrograde amnesia produced by electrical stimulation of the amygdala: attenuation with adrenergic antagonists.
Topics: Amnesia; Amnesia, Retrograde; Amygdala; Animals; Electric Stimulation; Electroshock; Humans; Male; M | 1981 |
Migrainous stroke causing thalamic infarction and amnesia during treatment with propranolol.
Topics: Adrenergic beta-Antagonists; Adult; Amnesia; Cerebrovascular Disorders; Female; Humans; Infarction; | 1997 |
Biochemical actions of sympathomimetic drugs which overcome cycloheximide-induced amnesia.
Topics: Adenosine Triphosphatases; Amnesia; Amphetamines; Animals; Brain; Chickens; Cycloheximide; Enzyme Ac | 1976 |
Amnestic syndrome associated with propranolol toxicity: a case report.
Topics: Aged; Aged, 80 and over; Amnesia; Brain; Female; Humans; Propranolol | 1992 |
The effects of atrial natriuretic peptide on electroconvulsive shock-induced amnesia in rats. Transmitter-mediated action.
Topics: Amnesia; Animals; Atrial Natriuretic Factor; Atropine; Avoidance Learning; Bicuculline; Electroshock | 1991 |
Blockade of beta 1- but not of beta 2-adrenergic receptors replicates propranolol's suppression of the cerebral spread of an engram in mice.
Topics: Adrenergic beta-Antagonists; Amnesia; Animals; Avoidance Learning; Betaxolol; Brain; Cerebellum; Hip | 1985 |
Delayed onset of the amnestic effect of posttraining beta-endorphin: effects of propranolol administered prior to retention testing.
Topics: Amnesia; Animals; beta-Endorphin; Endorphins; Male; Memory; Mice; Naloxone; Propranolol; Receptors, | 1985 |
Reversal of scopolamine-induced amnesia by phosphatidylserine in rats.
Topics: Amnesia; Animals; Avoidance Learning; Brain Chemistry; Male; Phosphatidylserines; Propranolol; Rats; | 1986 |
Proceedings: The effect of alpha-methyl-p-tyrosine, p-chlorophenylalanine, methysergide and propranolol on CO2-induced amnesia in rats.
Topics: Amnesia; Animals; Carbon Dioxide; Electroshock; Fenclonine; Humans; Methyltyrosines; Methysergide; P | 1973 |