Page last updated: 2024-11-03

propofol and Lung Diseases

propofol has been researched along with Lung Diseases in 31 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Lung Diseases: Pathological processes involving any part of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"To assess safety and efficacy of propofol and thiopental for refractory status epilepticus (RSE) in children, the authors reviewed 34 episodes of RSE."9.11Propofol and thiopental for refractory status epilepticus in children. ( Blussé van Oud-Alblas, HJ; Braun, KP; Malingré, M; van Gestel, JP; van Nieuwenhuizen, O; Ververs, FF, 2005)
"To investigate the protective efficacy of propofol against lung injury during hemorrhagic shock and resuscitation among Rhesus macaques."7.71[Effect of propofol on protecting Rhesus macaques from reperfusion lung injury during hemorrhagic shock and resuscitation]. ( Huang, X; Song, Q; Wang, M; Zhang, H, 2002)
"To assess safety and efficacy of propofol and thiopental for refractory status epilepticus (RSE) in children, the authors reviewed 34 episodes of RSE."5.11Propofol and thiopental for refractory status epilepticus in children. ( Blussé van Oud-Alblas, HJ; Braun, KP; Malingré, M; van Gestel, JP; van Nieuwenhuizen, O; Ververs, FF, 2005)
"During SLT or BLT, management of anesthesia with propofol and remifentanil provides a stable hemodynamic and medical support."3.83Management of Anesthesia during Lung Transplantations in a Single Turkish Center. ( Akarsu Ayazoğlu, T; Baysal, A; Dedemoğlu, M; Gul, YG; Onk, A; Onk, D; Ozensoy, A, 2016)
"To investigate the protective efficacy of propofol against lung injury during hemorrhagic shock and resuscitation among Rhesus macaques."3.71[Effect of propofol on protecting Rhesus macaques from reperfusion lung injury during hemorrhagic shock and resuscitation]. ( Huang, X; Song, Q; Wang, M; Zhang, H, 2002)
"Recent studies have shown that etomidate is associated with fewer serious adverse events than propofol and has a noninferior sedative effect."2.87Efficacy and safety of etomidate-midazolam for screening colonoscopy in the elderly: A prospective double-blinded randomized controlled study. ( Choi, HS; Choi, SJ; Chun, HJ; Jeen, YT; Keum, B; Kim, CD; Kim, ES; Kim, SH; Kim, W; Lee, BJ; Lee, HS; Lee, JM; Min, G; Park, JJ, 2018)
"To analyse the effects of combined acupuncture anesthesia on surgical dosage and serum interleukin-4 (IL-4), interleukin-10 (IL-10) of pneumonectomy patients."2.87Effect of Combined Acupuncture Anesthesia on Surgical Dosage and Serum IL-4, IL-10 of Pneumonectomy Patients. ( Shi, X; Xie, D; Zhang, Y, 2018)
" 5 mg was used; during surgery, the anesthesia induction was followed with intravenous injection of fentanyl citrate, propofol and rocuronium bromide and the dosage was increased accordingly; after surgery, the analgesia pump was applied."2.80[Clinical research of lung resection surgery with microinjection acupuncture and drug anesthesia instead of traditional acupuncture anesthesia]. ( Min, Y; Shi, L; Zhou, H; Zhu, Y, 2015)
"The risk and prognosis of aspiration pneumonia (AP) after endoscopic submucosal dissection (ESD) are inconsistent among studies."2.72Incidence rates, risk factors, and outcomes of aspiration pneumonia after gastric endoscopic submucosal dissection: A systematic review and meta-analysis. ( Gao, Y; Li, Y; Liu, H; Ma, H; Ma, X; Qu, H; Tang, D; Xu, L; Yang, Y; Yuan, F; Zhan, S; Zhang, W, 2021)
" A pharmacokinetic profile of P with its metabolites is shown, and some preliminary pharmacokinetic parameters of P and Q glucuronides are given."2.69Direct high-performance liquid chromatography determination of propofol and its metabolite quinol with their glucuronide conjugates and preliminary pharmacokinetics in plasma and urine of man. ( Bleeker, CP; de Grood, PM; Lagerwerf, AJ; Vree, TB, 1999)
"Propofol was administered by continuous infusion at an initial rate of 5 microg/kg per min and titrated as needed."2.69Effects of propofol containing EDTA on mineral metabolism in medical ICU patients with pulmonary dysfunction. ( Abraham, E; Hall, JB; Papadakos, PJ; Tharratt, RS; Williams, GJ, 2000)
" Patients' clinical data, procedure time, medications and any adverse events were recorded."1.37Titrated sedation with propofol for medical thoracoscopy: a feasibility and safety study. ( Cartier, V; Diaper, J; Frey, JG; Licker, M; Purek, L; Schnyder, JM; Tschopp, JM, 2011)
"Propofol was administered with a target controlled infusion setting with the target blood concentration of 10 micrograms."1.32[Propofol anesthesia for fetal sedation]. ( Kubo, K; Murao, K; Nakao, S; Ohashi, A; Shingu, K; Takeyasu, A, 2004)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (9.68)18.2507
2000's13 (41.94)29.6817
2010's11 (35.48)24.3611
2020's4 (12.90)2.80

Authors

AuthorsStudies
Zhiguo, Y1
Nanxiang, Z1
Jinyu, M1
Zhou, D1
Zhu, X1
Wang, L1
Yang, X1
Liu, Y1
Zhang, X1
Barends, CRM1
Driesens, MK1
van Amsterdam, K1
Struys, MMRF1
Absalom, AR1
Tang, D1
Yuan, F1
Ma, X1
Qu, H1
Li, Y1
Zhang, W1
Ma, H1
Liu, H1
Yang, Y1
Xu, L1
Gao, Y1
Zhan, S1
Li, XF1
Hu, JR1
Wu, Y1
Chen, Y1
Zhang, MQ1
Yu, H1
de la Gala, F1
Piñeiro, P1
Reyes, A1
Vara, E1
Olmedilla, L1
Cruz, P1
Garutti, I1
Lee, JM4
Min, G2
Kim, SH2
Choi, HS2
Kim, ES2
Keum, B2
Jeen, YT2
Chun, HJ2
Lee, HS2
Kim, CD2
Park, JJ1
Lee, BJ1
Choi, SJ1
Kim, W1
Xie, D1
Shi, X1
Zhang, Y1
Seo, YS1
Um, SH1
Kar Kurt, Ö1
Talay, F1
Karğı, A1
Yaşar, Z1
Tuğ, T1
Min, Y1
Zhu, Y1
Zhou, H1
Shi, L1
Akarsu Ayazoğlu, T1
Ozensoy, A1
Dedemoğlu, M1
Baysal, A1
Gul, YG1
Onk, D1
Onk, A1
Voigtsberger, S1
Lachmann, RA1
Leutert, AC1
Schläpfer, M1
Booy, C1
Reyes, L1
Urner, M1
Schild, J1
Schimmer, RC1
Beck-Schimmer, B1
Tschopp, JM1
Purek, L1
Frey, JG1
Schnyder, JM1
Diaper, J1
Cartier, V1
Licker, M1
Lee, JJ1
Kim, GH1
Kim, JA1
Yang, M1
Ahn, HJ1
Sim, WS1
Park, KJ1
Jun, BH1
Guo, Y1
Zhang, H2
Feng, X1
Wang, A1
Song, Q1
Wang, M1
Huang, X1
Hansen, LN1
Ravn, JB1
Yndgaard, S1
Hung, CJ1
Liu, FY1
Shaiu, YC1
Kao, A1
Lin, CC1
Lee, CC1
Kubo, K1
Murao, K1
Takeyasu, A1
Ohashi, A1
Nakao, S1
Shingu, K1
Habib, AS1
Helsley, SE1
Millar, S1
Deballi, P1
Muir, HA1
Minogue, SC1
Morrisson, M1
Ansermino, M1
Balyasnikova, IV1
Visintine, DJ1
Gunnerson, HB1
Paisansathan, C1
Baughman, VL1
Minshall, RD1
Danilov, SM1
van Gestel, JP1
Blussé van Oud-Alblas, HJ1
Malingré, M1
Ververs, FF1
Braun, KP1
van Nieuwenhuizen, O1
Yumoto, M1
Nishida, O1
Nakamura, F1
Katsuya, H1
Akyol, A2
Ulusoy, H1
Imamoğlu, M1
Cay, A1
Yuluğ, E1
Alver, A1
Ertürk, E1
Koşucu, M1
Beşir, A1
Ozen, I1
Vargo, JJ1
Holub, JL1
Faigel, DO1
Lieberman, DA1
Eisen, GM1
Gempeler, F1
Elston, AC1
Thompson, SP1
Park, GR1
Vree, TB1
Lagerwerf, AJ1
Bleeker, CP1
de Grood, PM1
Abraham, E1
Papadakos, PJ1
Tharratt, RS1
Hall, JB1
Williams, GJ1
Lindholm, M1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Using Thoracic Paravertebral Block for Perioperative Lung Preservation During VATS Pulmonary Surgery: A Dual Center Randomized Controlled Trial[NCT05922449]302 participants (Anticipated)Interventional2023-07-01Recruiting
Assessment of Breathing Using an Under-bed Weighing Scale[NCT04736212]16 participants (Actual)Observational2021-03-24Completed
STUDY OF PULMONARY AND SYSTEMIC INFLAMMATORY RESPONSE SECONDARY TO LUNG RESECTION SURGERY USING INTRAVENOUS ANESTHESIA VERSUS INHALATION ANESTHESIA WITH HALOGENATED AGENTS[NCT02168751]Phase 4180 participants (Actual)Interventional2012-09-30Completed
A Randomized Pilot Clinical Trial of the Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction of Sevoflurane in Patient's Whit ARDS Secondary to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2)[NCT04998253]Early Phase 124 participants (Actual)Interventional2020-10-01Completed
Effect of BIS Monitoring on Propofol Usage During Elective Bronchoscopy[NCT01592513]80 participants (Anticipated)Interventional2012-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for propofol and Lung Diseases

ArticleYear
Incidence rates, risk factors, and outcomes of aspiration pneumonia after gastric endoscopic submucosal dissection: A systematic review and meta-analysis.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:6

    Topics: Cerebrovascular Disorders; Comorbidity; Deep Sedation; Endoscopic Mucosal Resection; Female; Humans;

2021
[Sedation for fiberoptic bronchoscopy: review of the literature].
    Tuberkuloz ve toraks, 2015, Volume: 63, Issue:1

    Topics: Analgesics, Opioid; Benzodiazepines; Bronchoscopy; Conscious Sedation; Fiber Optic Technology; Human

2015

Trials

11 trials available for propofol and Lung Diseases

ArticleYear
Which Anesthesia Regimen Is Best to Reduce Pulmonary Complications After Head and Neck Surgery?
    The Laryngoscope, 2021, Volume: 131, Issue:1

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2021
Comparative Effect of Propofol and Volatile Anesthetics on Postoperative Pulmonary Complications After Lung Resection Surgery: A Randomized Clinical Trial.
    Anesthesia and analgesia, 2021, 10-01, Volume: 133, Issue:4

    Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; China; Desflurane; Female; Humans; L

2021
Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchoalveolar L

2017
Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchoalveolar L

2017
Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchoalveolar L

2017
Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchoalveolar L

2017
Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchoalveolar L

2017
Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchoalveolar L

2017
Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchoalveolar L

2017
Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchoalveolar L

2017
Postoperative pulmonary complications, pulmonary and systemic inflammatory responses after lung resection surgery with prolonged one-lung ventilation. Randomized controlled trial comparing intravenous and inhalational anaesthesia.
    British journal of anaesthesia, 2017, Oct-01, Volume: 119, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchoalveolar L

2017
Efficacy and safety of etomidate-midazolam for screening colonoscopy in the elderly: A prospective double-blinded randomized controlled study.
    Medicine, 2018, Volume: 97, Issue:20

    Topics: Aged; Anesthetics, Intravenous; Cardiovascular Diseases; Colonoscopy; Double-Blind Method; Etomidate

2018
Effect of Combined Acupuncture Anesthesia on Surgical Dosage and Serum IL-4, IL-10 of Pneumonectomy Patients.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018, Volume: 28, Issue:11

    Topics: Acupuncture Analgesia; Anesthetics, Intravenous; Blood Pressure; Enzyme-Linked Immunosorbent Assay;

2018
Using Etomidate and Midazolam for Screening Colonoscopies Results in More Stable Hemodynamic Responses in Patients of All Ages.
    Gut and liver, 2019, 11-15, Volume: 13, Issue:6

    Topics: Adult; Aged; Cardiovascular Diseases; Colonic Diseases; Colonoscopy; Double-Blind Method; Etomidate;

2019
[Clinical research of lung resection surgery with microinjection acupuncture and drug anesthesia instead of traditional acupuncture anesthesia].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2015, Volume: 35, Issue:4

    Topics: Acupuncture Analgesia; Acupuncture Points; Adult; Aged; Anesthetics, Intravenous; Blood Pressure; Fe

2015
Comparison of pulmonary morbidity using sevoflurane or propofol-remifentanil anesthesia in an Ivor Lewis operation.
    Journal of cardiothoracic and vascular anesthesia, 2012, Volume: 26, Issue:5

    Topics: Aged; Anesthesia, Inhalation; Esophagoscopy; Female; Humans; Lung Diseases; Male; Methyl Ethers; Mid

2012
Propofol and thiopental for refractory status epilepticus in children.
    Neurology, 2005, Aug-23, Volume: 65, Issue:4

    Topics: Anticonvulsants; Child; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Sc

2005
Direct high-performance liquid chromatography determination of propofol and its metabolite quinol with their glucuronide conjugates and preliminary pharmacokinetics in plasma and urine of man.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Jan-22, Volume: 721, Issue:2

    Topics: Anesthetics, Intravenous; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Drug

1999
Effects of propofol containing EDTA on mineral metabolism in medical ICU patients with pulmonary dysfunction.
    Intensive care medicine, 2000, Volume: 26 Suppl 4

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthetics, Intravenous; Calcium; Chelating A

2000

Other Studies

18 other studies available for propofol and Lung Diseases

ArticleYear
Analysis of comparative anesthetic effects of sevoflurane and propofol on lung and cognitive functions.
    Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:5(Special)

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition; Female; Gene Expression Regulation; Hu

2019
Moderate-to-Deep Sedation Using Target-Controlled Infusions of Propofol and Remifentanil: Adverse Events and Risk Factors: A Retrospective Cohort Study of 2937 Procedures.
    Anesthesia and analgesia, 2020, Volume: 131, Issue:4

    Topics: Aged; Body Mass Index; Cardiopulmonary Resuscitation; Cohort Studies; Critical Care; Deep Sedation;

2020
Management of Anesthesia during Lung Transplantations in a Single Turkish Center.
    Archives of Iranian medicine, 2016, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Anesthesia; Anesthetics, Intravenous; Cardiopulmonary Bypass; Extracorporeal Memb

2016
Sevoflurane ameliorates gas exchange and attenuates lung damage in experimental lipopolysaccharide-induced lung injury.
    Anesthesiology, 2009, Volume: 111, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Cell Count; Cells, C

2009
Titrated sedation with propofol for medical thoracoscopy: a feasibility and safety study.
    Respiration; international review of thoracic diseases, 2011, Volume: 82, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Conscious Sedation; Consciousness Monitors; Feasibility Studies; Fem

2011
A retrospective study of risk factors for cardiopulmonary events during propofol-mediated gastrointestinal endoscopy in patients aged over 70 years.
    Middle East journal of anaesthesiology, 2012, Volume: 21, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anesthetics, Intravenous; Body Mass Index; Cardiovascular Dise

2012
[Effect of propofol on protecting Rhesus macaques from reperfusion lung injury during hemorrhagic shock and resuscitation].
    Zhonghua yi xue za zhi, 2002, Sep-10, Volume: 82, Issue:17

    Topics: Animals; Anticonvulsants; Lactates; Lung; Lung Diseases; Macaca mulatta; Male; Malondialdehyde; Prop

2002
Early extubation after single-lung transplantation: analysis of the first 106 cases.
    Journal of cardiothoracic and vascular anesthesia, 2003, Volume: 17, Issue:1

    Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Combined; Female; Fentanyl; Force

2003
Assessing transient pulmonary injury induced by volatile anesthetics by increased lung uptake of technetium-99m hexamethylpropylene amine oxime.
    Lung, 2003, Volume: 181, Issue:1

    Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Endothelium, Vascular; Female; Fenta

2003
[Propofol anesthesia for fetal sedation].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:3

    Topics: Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Anesthetics, Intravenous; Cesarean Section;

2004
Anesthesia for cesarean section in a patient with spinal muscular atrophy.
    Journal of clinical anesthesia, 2004, Volume: 16, Issue:3

    Topics: Adult; Alfentanil; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Intravenous; Cesarean

2004
Laryngo-tracheo-bronchial stenosis in a patient with primary pulmonary amyloidosis: a case report and brief review.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:8

    Topics: Amyloidosis; Anesthesia, General; Anesthetics, Intravenous; Bronchial Diseases; High-Frequency Jet V

2004
Propofol attenuates lung endothelial injury induced by ischemia-reperfusion and oxidative stress.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:4

    Topics: Anesthetics, Intravenous; Animals; CHO Cells; Cricetinae; Endothelium; Enzyme-Linked Immunosorbent A

2005
Propofol attenuates oxidant-induced acute lung injury in an isolated perfused rabbit-lung model.
    Journal of anesthesia, 2005, Volume: 19, Issue:4

    Topics: Animals; Antioxidants; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrogen

2005
Does propofol or caffeic acid phenethyl ester prevent lung injury after hindlimb ischaemia-reperfusion in ventilated rats?
    Injury, 2006, Volume: 37, Issue:5

    Topics: Animals; Caffeic Acids; Free Radical Scavengers; Hindlimb; Ischemia; Lung; Lung Diseases; Male; Malo

2006
Risk factors for cardiopulmonary events during propofol-mediated upper endoscopy and colonoscopy.
    Alimentary pharmacology & therapeutics, 2006, Sep-15, Volume: 24, Issue:6

    Topics: Adult; Age Factors; Aged; Anesthesia; Cardiovascular Diseases; Cohort Studies; Colonoscopy; Endoscop

2006
Propofol and intralipid cause creaming of serum from critically ill patients.
    Anaesthesia, 1994, Volume: 49, Issue:1

    Topics: Acute-Phase Proteins; Adult; Aged; Anesthesia, Intravenous; Critical Illness; Dose-Response Relation

1994
Critically ill patients and fat emulsions.
    Minerva anestesiologica, 1992, Volume: 58, Issue:10

    Topics: Critical Care; Critical Illness; Fat Emulsions, Intravenous; Humans; Lung Diseases; Propofol

1992
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