propofol and Encephalopathy, Hepatic
propofol has been researched along with Encephalopathy, Hepatic in 14 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Propofol-based sedation exacerbated MHE after EIS similarly to midazolam-based sedation in patients with liver cirrhosis." | 9.27 | Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( Hashimoto, M; Hikichi, T; Irie, H; Kikuchi, H; Konno, N; Nakamura, J; Obara, K; Ohira, H; Sato, Y; Sugimoto, M; Suzuki, R; Takagi, T; Takasumi, M; Watanabe, K, 2018) |
"Our study aimed to investigate the effects of propofol medium and long chain lipid emulsion on cognitive function of the patients with hepatic encephalopathy undergoing hemofiltration treatment." | 9.24 | Effects on cognitive function of propofol medium and long chain lipid emulsion in patients with hepatic encephalopathy. ( Ding, L; Hu, J; Yu, D; Yu, S, 2017) |
"Sedation with propofol has a shorter time recovery and a shorter time to discharge than midazolam and does not exacerbate sub-clinical hepatic encephalopathy in patients with compensated liver cirrhosis." | 9.15 | Sub-clinical hepatic encephalopathy in cirrhotic patients is not aggravated by sedation with propofol compared to midazolam: a randomized controlled study. ( Alex, I; Kamal, D; Khamaysi, I; Nimer, A; Olga, A; Vladimir, M; William, N, 2011) |
"Midazolam sedation for upper gastrointestinal (GI) endoscopy exacerbates minimal hepatic encephalopathy (HE) in patients with liver cirrhosis, therefore an alternative drug regimen for these patients is warranted." | 9.14 | Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study. ( Frenz, MB; Lechowicz, I; Riphaus, A; Wehrmann, T, 2009) |
"The risk of hepatic encephalopathy (HE) precipitated by propofol has not been established." | 7.75 | Deep sedation with propofol does not precipitate hepatic encephalopathy during elective upper endoscopy. ( Amorós, A; Aparicio, JR; Casellas, JA; Garmendia, M; Jover, R; Martínez, J, 2009) |
"Propofol-based sedation exacerbated MHE after EIS similarly to midazolam-based sedation in patients with liver cirrhosis." | 5.27 | Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( Hashimoto, M; Hikichi, T; Irie, H; Kikuchi, H; Konno, N; Nakamura, J; Obara, K; Ohira, H; Sato, Y; Sugimoto, M; Suzuki, R; Takagi, T; Takasumi, M; Watanabe, K, 2018) |
"Our study aimed to investigate the effects of propofol medium and long chain lipid emulsion on cognitive function of the patients with hepatic encephalopathy undergoing hemofiltration treatment." | 5.24 | Effects on cognitive function of propofol medium and long chain lipid emulsion in patients with hepatic encephalopathy. ( Ding, L; Hu, J; Yu, D; Yu, S, 2017) |
" Baseline psychomotor performance was more impaired in cirrhotic patients, but propofol was not associated with deteriorated psychomotor function even in cirrhotic patients with a minimal hepatic encephalopathy." | 5.19 | Is propofol safe when administered to cirrhotic patients during sedative endoscopy? ( Byun, KS; Choi, JH; Choung, RS; Hyun, JJ; Jung, SW; Kim, JH; Kim, KJ; Koo, JS; Lee, BJ; Lee, SW; Ryu, HS; Seo, YS; Suh, SJ; Um, SH; Yeon, JE; Yim, HJ; Yoon, EL, 2014) |
"Sedation with propofol has a shorter time recovery and a shorter time to discharge than midazolam and does not exacerbate sub-clinical hepatic encephalopathy in patients with compensated liver cirrhosis." | 5.15 | Sub-clinical hepatic encephalopathy in cirrhotic patients is not aggravated by sedation with propofol compared to midazolam: a randomized controlled study. ( Alex, I; Kamal, D; Khamaysi, I; Nimer, A; Olga, A; Vladimir, M; William, N, 2011) |
"Midazolam sedation for upper gastrointestinal (GI) endoscopy exacerbates minimal hepatic encephalopathy (HE) in patients with liver cirrhosis, therefore an alternative drug regimen for these patients is warranted." | 5.14 | Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study. ( Frenz, MB; Lechowicz, I; Riphaus, A; Wehrmann, T, 2009) |
"The risk of hepatic encephalopathy (HE) precipitated by propofol has not been established." | 3.75 | Deep sedation with propofol does not precipitate hepatic encephalopathy during elective upper endoscopy. ( Amorós, A; Aparicio, JR; Casellas, JA; Garmendia, M; Jover, R; Martínez, J, 2009) |
"Midazolam was associated with the deterioration of psychometric scores for a longer period than propofol." | 2.52 | Propofol versus midazolam for upper gastrointestinal endoscopy in cirrhotic patients: a meta-analysis of randomized controlled trials. ( Chen, CY; Chen, TL; Ko, CL; Lin, YC; Lou, HY; Tam, KW; Tsai, HC, 2015) |
"Hepatic encephalopathy is a neurologic syndrome secondary to liver failure that causes cognitive and motor abnormalities." | 1.33 | Functional abnormalities of the motor tract in the rat after portocaval anastomosis and after carbon tetrachloride induction of cirrhosis. ( Bartolí, R; Chatauret, N; Córdoba, J; Odena, G; Oria, M; Planas, R; Raguer, N, 2006) |
Research
Studies (14)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (7.14) | 18.2507 |
2000's | 4 (28.57) | 29.6817 |
2010's | 8 (57.14) | 24.3611 |
2020's | 1 (7.14) | 2.80 |
Authors
Authors | Studies |
---|---|
Jeong, J | 1 |
Jung, K | 1 |
Seo, KI | 1 |
Yun, BC | 1 |
Han, BH | 1 |
Lee, SU | 1 |
Moon, W | 1 |
Yu, S | 1 |
Hu, J | 1 |
Ding, L | 1 |
Yu, D | 1 |
Watanabe, K | 1 |
Hikichi, T | 1 |
Takagi, T | 1 |
Suzuki, R | 1 |
Nakamura, J | 1 |
Sugimoto, M | 1 |
Kikuchi, H | 1 |
Konno, N | 1 |
Takasumi, M | 1 |
Sato, Y | 1 |
Hashimoto, M | 1 |
Irie, H | 1 |
Obara, K | 1 |
Ohira, H | 1 |
Suh, SJ | 1 |
Yim, HJ | 1 |
Yoon, EL | 1 |
Lee, BJ | 1 |
Hyun, JJ | 1 |
Jung, SW | 1 |
Koo, JS | 1 |
Kim, JH | 1 |
Kim, KJ | 1 |
Choung, RS | 1 |
Seo, YS | 1 |
Yeon, JE | 1 |
Um, SH | 1 |
Byun, KS | 1 |
Lee, SW | 1 |
Choi, JH | 1 |
Ryu, HS | 1 |
Tsai, HC | 1 |
Lin, YC | 1 |
Ko, CL | 1 |
Lou, HY | 1 |
Chen, TL | 1 |
Tam, KW | 1 |
Chen, CY | 1 |
Amorós, A | 1 |
Aparicio, JR | 1 |
Garmendia, M | 1 |
Casellas, JA | 1 |
Martínez, J | 1 |
Jover, R | 1 |
Riphaus, A | 1 |
Lechowicz, I | 1 |
Frenz, MB | 1 |
Wehrmann, T | 1 |
Khamaysi, I | 1 |
William, N | 1 |
Olga, A | 1 |
Alex, I | 1 |
Vladimir, M | 1 |
Kamal, D | 1 |
Nimer, A | 1 |
Okawa, H | 1 |
Ono, T | 1 |
Hashiba, E | 1 |
Tsubo, T | 1 |
Ishihara, H | 1 |
Hirota, K | 1 |
Sharma, P | 2 |
Singh, S | 2 |
Sharma, BC | 2 |
Kumar, M | 1 |
Garg, H | 1 |
Kumar, A | 1 |
Sarin, SK | 1 |
Oria, M | 1 |
Raguer, N | 1 |
Chatauret, N | 1 |
Bartolí, R | 1 |
Odena, G | 1 |
Planas, R | 1 |
Córdoba, J | 1 |
Braunfeld, MY | 1 |
Wijdicks, EF | 1 |
Nyberg, SL | 1 |
Reviews
1 review available for propofol and Encephalopathy, Hepatic
Article | Year |
---|---|
Propofol versus midazolam for upper gastrointestinal endoscopy in cirrhotic patients: a meta-analysis of randomized controlled trials.
Topics: Anesthesia Recovery Period; Bradycardia; Deep Sedation; Endoscopy, Gastrointestinal; Fibrosis; Hepat | 2015 |
Trials
7 trials available for propofol and Encephalopathy, Hepatic
Article | Year |
---|---|
Effects on cognitive function of propofol medium and long chain lipid emulsion in patients with hepatic encephalopathy.
Topics: Aged; Biomarkers; China; Cognition; Drug Compounding; Fat Emulsions, Intravenous; Female; Hemofiltra | 2017 |
Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial.
Topics: Aged; Esophageal and Gastric Varices; Female; Hepatic Encephalopathy; Humans; Hypnotics and Sedative | 2018 |
Is propofol safe when administered to cirrhotic patients during sedative endoscopy?
Topics: Adult; Endoscopy, Gastrointestinal; Female; Hepatic Encephalopathy; Humans; Hypnotics and Sedatives; | 2014 |
Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study.
Topics: Aged; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Hepatic Encephalopathy; H | 2009 |
Sub-clinical hepatic encephalopathy in cirrhotic patients is not aggravated by sedation with propofol compared to midazolam: a randomized controlled study.
Topics: Adult; Aged; Anesthesia Recovery Period; Cognition; Conscious Sedation; Endoscopy, Gastrointestinal; | 2011 |
Propofol in patients with cirrhosis and minimal hepatic encephalopathy.
Topics: Anesthetics, Intravenous; Endoscopy, Gastrointestinal; Hepatic Encephalopathy; Humans; Liver Cirrhos | 2011 |
Propofol sedation during endoscopy in patients with cirrhosis, and utility of psychometric tests and critical flicker frequency in assessment of recovery from sedation.
Topics: Adult; Aged; Anesthesia Recovery Period; Cognition; Endoscopy, Gastrointestinal; Female; Flicker Fus | 2011 |
Other Studies
6 other studies available for propofol and Encephalopathy, Hepatic
Article | Year |
---|---|
Propofol alone prevents worsening hepatic encephalopathy rather than midazolam alone or combined sedation after esophagogastroduodenoscopy in compensated or decompensated cirrhotic patients.
Topics: Conscious Sedation; Endoscopy, Digestive System; Hepatic Encephalopathy; Humans; Hypnotics and Sedat | 2020 |
Deep sedation with propofol does not precipitate hepatic encephalopathy during elective upper endoscopy.
Topics: Cohort Studies; Conscious Sedation; Elective Surgical Procedures; Endoscopy, Gastrointestinal; Femal | 2009 |
Use of bispectral index monitoring for a patient with hepatic encephalopathy requiring living donor liver transplantation: a case report.
Topics: Adult; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Consciousness Monitors; Fent | 2011 |
Functional abnormalities of the motor tract in the rat after portocaval anastomosis and after carbon tetrachloride induction of cirrhosis.
Topics: Anastomosis, Surgical; Anesthetics, Intravenous; Animals; Carbon Tetrachloride; Disease Models, Anim | 2006 |
Case presentation: fulminant hepatic failure.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Brain Death; Brain Edema; Female; Hepatic Encephalop | 1999 |
Propofol to control intracranial pressure in fulminant hepatic failure.
Topics: Adolescent; Adult; Anticonvulsants; Female; Hepatic Encephalopathy; Humans; Intracranial Hypertensio | 2002 |