propofol and Coronary Heart Disease
propofol has been researched along with Coronary Heart Disease in 30 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"It is skeptical about cardioprotective property of sevoflurane in patients undergoing noncardiac surgery, especially in the elderly patients with coronary heart disease." | 9.24 | Randomized comparison of sevoflurane versus propofol-remifentanil on the cardioprotective effects in elderly patients with coronary heart disease. ( Feng, X; Lin, W; Shen, S; Sun, J; Wang, H; Zhang, Y, 2017) |
" After exclusion of potential causes for this phenomenon, it was attributed to perioperative intravenous propofol infusion causing propofol infusion syndrome." | 7.75 | Propofol infusion syndrome in adult cardiac surgery. ( Balacumaraswami, L; Ilyas, MI; Palin, C; Ratnatunga, C, 2009) |
"003 mg/kg fentanyl the patients received the induction agent in the above-mentioned dosage within 40 s followed by 0." | 6.66 | [Comparative hemodynamic study of anesthesia induction with propofol (Diprivan), thiopental, methohexital, etomidate and midazolam in patients with coronary disease]. ( Boldt, J; Börner, U; Hempelmann, G; Kling, D; Laubenthal, H, 1987) |
"Fentanyl was also associated with a significant decrease in heart rate (16%) resulting in a decrease in CI, whereas stroke index and end diastolic volume did not change." | 5.27 | Left ventricular function during propofol and fentanyl anesthesia in patients with coronary artery disease: assessment with a radionuclide approach. ( Cozian, AY; Farinotti, R; Hélias, JH; Juge, CM; Lepage, JY; Pinaud, ML; Souron, RJ, 1988) |
"It is skeptical about cardioprotective property of sevoflurane in patients undergoing noncardiac surgery, especially in the elderly patients with coronary heart disease." | 5.24 | Randomized comparison of sevoflurane versus propofol-remifentanil on the cardioprotective effects in elderly patients with coronary heart disease. ( Feng, X; Lin, W; Shen, S; Sun, J; Wang, H; Zhang, Y, 2017) |
"Comparison of the length of mechanical ventilation and postoperative complications after coronary surgery in elderly patients anaesthetised with propofol associated with either alfentanil or remifentanil." | 5.11 | [Continuous infusion of remifentanil and target-controlled infusion of propofol for coronary surgery in elderly patients: comparison with continuous infusion of remifentanil and propofol]. ( Blin, D; Chavanon, O; Durand, M; Gardellin, M; Girardet, P; Maitrasse, B; Robin, S, 2004) |
" After exclusion of potential causes for this phenomenon, it was attributed to perioperative intravenous propofol infusion causing propofol infusion syndrome." | 3.75 | Propofol infusion syndrome in adult cardiac surgery. ( Balacumaraswami, L; Ilyas, MI; Palin, C; Ratnatunga, C, 2009) |
"003 mg/kg fentanyl the patients received the induction agent in the above-mentioned dosage within 40 s followed by 0." | 2.66 | [Comparative hemodynamic study of anesthesia induction with propofol (Diprivan), thiopental, methohexital, etomidate and midazolam in patients with coronary disease]. ( Boldt, J; Börner, U; Hempelmann, G; Kling, D; Laubenthal, H, 1987) |
"Thiopental, however, was associated with a dose-dependent decrease in systolic shortening, which was significantly greater in the ischemic segment." | 1.28 | Influence of thiopental, etomidate, and propofol on regional myocardial function in the normal and acute ischemic heart segment in dogs. ( Adriaensen, HF; De Hert, SG; Vermeyen, KM, 1990) |
"Fentanyl was also associated with a significant decrease in heart rate (16%) resulting in a decrease in CI, whereas stroke index and end diastolic volume did not change." | 1.27 | Left ventricular function during propofol and fentanyl anesthesia in patients with coronary artery disease: assessment with a radionuclide approach. ( Cozian, AY; Farinotti, R; Hélias, JH; Juge, CM; Lepage, JY; Pinaud, ML; Souron, RJ, 1988) |
"Propofol was used at a dose of 2 mg X kg-1." | 1.27 | [Hemodynamic effects of propofol used alone for the induction of anesthesia]. ( Jullian-Papouin, H; Manelli, JC; Paulin, M; Roquebert, PO, 1987) |
Research
Studies (30)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (36.67) | 18.7374 |
1990's | 11 (36.67) | 18.2507 |
2000's | 7 (23.33) | 29.6817 |
2010's | 1 (3.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Zhang, Y | 1 |
Lin, W | 1 |
Shen, S | 1 |
Wang, H | 1 |
Feng, X | 1 |
Sun, J | 1 |
Ilyas, MI | 1 |
Balacumaraswami, L | 1 |
Palin, C | 1 |
Ratnatunga, C | 1 |
Hiraoka, H | 1 |
Yamamoto, K | 1 |
Okano, N | 1 |
Morita, T | 1 |
Goto, F | 1 |
Horiuchi, R | 1 |
Gardellin, M | 1 |
Durand, M | 1 |
Maitrasse, B | 1 |
Chavanon, O | 1 |
Robin, S | 1 |
Blin, D | 1 |
Girardet, P | 1 |
Cillo, JE | 1 |
Finn, R | 1 |
Al-Khudhairi, D | 1 |
Gordon, G | 1 |
Morgan, M | 1 |
Whitwam, JG | 1 |
Duthie, DJ | 1 |
Stevens, JJ | 1 |
Doyle, AR | 1 |
Baddoo, HH | 1 |
Marty, J | 1 |
Higgins, TL | 1 |
Yared, JP | 1 |
Estafanous, FG | 1 |
Coyle, JP | 1 |
Ko, HK | 1 |
Goodale, DB | 1 |
Lischke, V | 1 |
Wilke, HJ | 1 |
Probst, S | 1 |
Behne, M | 1 |
Kessler, P | 1 |
Mayer, N | 1 |
Legat, K | 1 |
Weinstabl, C | 1 |
Zimpfer, M | 1 |
Gerhardt, MA | 1 |
Grichnik, KP | 1 |
Kakinohana, M | 1 |
Saitoh, T | 1 |
Okuda, Y | 1 |
Kazmaier, S | 1 |
Hanekop, GG | 1 |
Buhre, W | 1 |
Weyland, A | 1 |
Busch, T | 1 |
Radke, OC | 1 |
Zoelffel, R | 1 |
Sonntag, H | 3 |
Pittarello, D | 1 |
Bonato, R | 1 |
Armellin, G | 1 |
Sorbara, C | 1 |
Haessler, R | 1 |
Madler, C | 1 |
Klasing, S | 1 |
Schwender, D | 1 |
Peter, K | 1 |
De Hert, SG | 2 |
Lepage, JY | 4 |
Pinaud, ML | 2 |
Helias, JH | 2 |
Cozian, AY | 2 |
Le Normand, Y | 1 |
Souron, RJ | 2 |
Kavanagh, BP | 1 |
Ryan, MP | 1 |
Cunningham, AJ | 1 |
Vermeyen, KM | 2 |
Adriaensen, HF | 1 |
Dupuy, P | 1 |
Pery, N | 1 |
Boisson, A | 1 |
Sirodot, M | 1 |
Langeron, O | 1 |
Payen, D | 1 |
Pinaud, M | 2 |
Hélias, J | 2 |
Cozian, A | 2 |
Juge, C | 2 |
Souron, R | 2 |
Stephan, H | 2 |
Seyde, WC | 1 |
Henze, T | 1 |
Textor, J | 1 |
Juge, CM | 1 |
Farinotti, R | 1 |
Kling, D | 1 |
Laubenthal, H | 1 |
Börner, U | 1 |
Boldt, J | 1 |
Hempelmann, G | 1 |
Schenk, HD | 1 |
Kettler, D | 1 |
Khambatta, HJ | 1 |
Paulin, M | 1 |
Jullian-Papouin, H | 1 |
Roquebert, PO | 1 |
Manelli, JC | 1 |
Erpels, FA | 1 |
Janssen, LA | 1 |
Beeckman, CP | 1 |
Hanegreefs, GH | 1 |
Patrick, MR | 1 |
Blair, IJ | 1 |
Feneck, RO | 1 |
Sebel, PS | 1 |
Clinical Trials (2)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
"Haemodynamic Stability During Induction of General Anesthesia With Propofol and Remifentanil: A Randomized, Controlled, Double-blind Study Comparing Equipotent Prophylactic Doses of Ephedrine, Phenylephrine, Norepinephrine vs Placebo."[NCT03864094] | Phase 4 | 99 participants (Anticipated) | Interventional | 2022-03-15 | Recruiting | ||
"Hemodynamic Stability During Induction of General Anesthesia With Propofol and Remifentanil: A Randomized, Controlled, Double-blind Study Comparing Medium and Low Remifentanil Doses."[NCT03861377] | Phase 4 | 99 participants (Actual) | Interventional | 2020-06-09 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trials
9 trials available for propofol and Coronary Heart Disease
Article | Year |
---|---|
Randomized comparison of sevoflurane versus propofol-remifentanil on the cardioprotective effects in elderly patients with coronary heart disease.
Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiac Output; Cardioto | 2017 |
Changes in drug plasma concentrations of an extensively bound and highly extracted drug, propofol, in response to altered plasma binding.
Topics: Adult; Aged; Analysis of Variance; Anesthetics, Intravenous; Biological Availability; Blood Proteins | 2004 |
[Continuous infusion of remifentanil and target-controlled infusion of propofol for coronary surgery in elderly patients: comparison with continuous infusion of remifentanil and propofol].
Topics: Aged; Anesthetics, Intravenous; Coronary Disease; Humans; Infusions, Intravenous; Orthopedic Procedu | 2004 |
Propofol versus midazolam for intensive care unit sedation after coronary artery bypass grafting.
Topics: Adult; Aged; Blood Pressure; Conscious Sedation; Coronary Artery Bypass; Coronary Disease; Drug Admi | 1994 |
Prolongation of the QT-interval during induction of anesthesia in patients with coronary artery disease.
Topics: Anesthesia, Intravenous; Blood Pressure; Coronary Disease; Electrocardiography; Etomidate; Female; F | 1994 |
[Alterations in left ventricular-arterial coupling and mechanical efficiency produced by remifentanil during cardiac anesthesia].
Topics: Aged; Anesthetics, Intravenous; Aorta; Cardiovascular Agents; Combined Modality Therapy; Coronary Ar | 2001 |
Left ventricular performance during propofol or methohexital anesthesia: isotopic and invasive cardiac monitoring.
Topics: Aged; Anesthesia, Intravenous; Coronary Disease; Gated Blood-Pool Imaging; Hemodynamics; Humans; Met | 1991 |
[Comparative hemodynamic study of anesthesia induction with propofol (Diprivan), thiopental, methohexital, etomidate and midazolam in patients with coronary disease].
Topics: Anesthesia, General; Anesthetics; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease | 1987 |
A comparison of the haemodynamic effects of propofol ('Diprivan') and thiopentone in patients with coronary artery disease.
Topics: Anesthesia, Intravenous; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Phenols; | 1985 |
Other Studies
21 other studies available for propofol and Coronary Heart Disease
Article | Year |
---|---|
Propofol infusion syndrome in adult cardiac surgery.
Topics: Acidosis, Lactic; Aged; Anesthetics, Intravenous; Blood Chemical Analysis; Cardiopulmonary Bypass; C | 2009 |
Hemodynamics in elderly coronary artery disease patients undergoing propofol sedation.
Topics: Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Intraveno | 2006 |
Acute cardiovascular changes following disoprofol. Effects in heavily sedated patients with coronary artery disease.
Topics: Anesthesia, Intravenous; Anesthetics; Coronary Disease; Hemodynamics; Humans; Male; Middle Aged; Phe | 1982 |
Remifentanil and coronary artery surgery.
Topics: Analgesics, Opioid; Coronary Disease; Drug Combinations; Humans; Length of Stay; Pancuronium; Piperi | 1995 |
[Coronary patient undergoing non cardiac surgery and Diprivan].
Topics: Anesthesia, Intravenous; Coronary Disease; Hemodynamics; Humans; Monitoring, Intraoperative; Propofo | 1994 |
Effects of propofol on the function of normal, collateral-dependent, and ischemic myocardium.
Topics: Animals; Collateral Circulation; Coronary Disease; Dogs; Female; Heart; Hemodynamics; Injections, In | 1993 |
Early extubation and neurologic examination following combined carotid endarterectomy and coronary artery bypass grafting using remifentanil.
Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Blood Pressure; Carotid St | 1998 |
[Anesthetic management of an emergency surgery for panperitonitis during an asthmatic attack].
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Inhalation; Coronary Disease; Duodenal | 2000 |
Myocardial consequences of remifentanil in patients with coronary artery disease.
Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Coronary Circulation; Coronary Disease; Heart Rate; | 2000 |
Myocardial consequences of remifentanil in patients with coronary artery disease.
Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Coronary Circulation; Coronary Disease; Heart Rate; | 2000 |
Myocardial consequences of remifentanil in patients with coronary artery disease.
Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Coronary Circulation; Coronary Disease; Heart Rate; | 2000 |
Myocardial consequences of remifentanil in patients with coronary artery disease.
Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Coronary Circulation; Coronary Disease; Heart Rate; | 2000 |
Propofol/fentanyl versus etomidate/fentanyl for the induction of anesthesia in patients with aortic insufficiency and coronary artery disease.
Topics: Adult; Anesthesia, General; Aortic Valve Insufficiency; Coronary Disease; Etomidate; Female; Fentany | 1992 |
Study on the effects of six intravenous anesthetic agents on regional ventricular function in dogs (thiopental, etomidate, propofol, fentanyl, sufentanil, alfentanil).
Topics: Alfentanil; Animals; Coronary Disease; Dogs; Etomidate; Female; Fentanyl; Hemodynamics; Infusions, I | 1991 |
Myocardial contractility and ischaemia in the isolated perfused rat heart with propofol and thiopentone.
Topics: Animals; Coronary Disease; Magnesium; Male; Myocardial Contraction; Myocardium; Perfusion; Potassium | 1991 |
Influence of thiopental, etomidate, and propofol on regional myocardial function in the normal and acute ischemic heart segment in dogs.
Topics: Animals; Coronary Disease; Dogs; Etomidate; Female; Heart; Hemodynamics; Infusions, Intravenous; Mal | 1990 |
[Myocardial depression induced by propofol (P) is not of ischemic origin].
Topics: Adult; Aged; Anesthesia; Anti-Arrhythmia Agents; Coronary Circulation; Coronary Disease; Heart Ventr | 1989 |
[Comparison of the effects of propofol and brietal on cardiac performance in coronary disease. Gamma-angioscintigraphy].
Topics: Aged; Coronary Disease; Heart; Hemodynamics; Humans; Methohexital; Middle Aged; Propofol; Radionucli | 1989 |
[Energy and amino acid metabolism in the human brain under Disoprivan anesthesia with various paCO2 values].
Topics: Amino Acids; Anesthesia, General; Anesthetics; Blood Glucose; Brain; Carbon Dioxide; Cerebrovascular | 1988 |
Left ventricular function during propofol and fentanyl anesthesia in patients with coronary artery disease: assessment with a radionuclide approach.
Topics: Aged; Aged, 80 and over; Anesthesia; Coronary Disease; Drug Combinations; Female; Fentanyl; Heart; H | 1988 |
Effects of propofol on cardiovascular dynamics, myocardial blood flow and myocardial metabolism in patients with coronary artery disease.
Topics: Adult; Anesthesia, Intravenous; Anesthetics; Coronary Artery Bypass; Coronary Circulation; Coronary | 1986 |
[Hemodynamic effects of propofol used alone for the induction of anesthesia].
Topics: Aged; Anesthesia, General; Anesthetics; Blood Pressure; Coronary Disease; Female; Hemodynamics; Huma | 1987 |
[Effect of propofol on left ventricular function in the coronary patient. Combined isotopic and hemodynamic studies].
Topics: Aged; Anesthetics; Cineangiography; Coronary Disease; Heart; Heart Ventricles; Hemodynamics; Humans; | 1987 |
Propofol-fentanyl anaesthesia for coronary bypass surgery in patients with good left ventricular function.
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics; Coronary Artery Bypass; Coronary Disease; Female; | 1987 |