propofol has been researched along with Burns in 33 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study evaluated the feasibility and effectiveness of using the bispectral index (BIS) to monitor anesthetic depth in patients with severe burns receiving intravenous target-controlled infusion (TCI) of remifentanil and propofol." | 9.20 | Bispectral index for monitoring anesthetic depth in patients with severe burns receiving target-controlled infusion of remifentanil and propofol. ( Guo, ZG; Hao, JH; Jia, XP; Li, P; Su, XJ; Wang, XY, 2015) |
| "In the burns group, significantly greater BIS values relating to increasing propofol TCI were noted at deeper anesthesia when compared with controls; at > or =3." | 9.11 | The relationship between bispectral index and targeted propofol concentration is biphasic in patients with major burns. ( Han, KW; Han, TH; Kil, HY; Kim, KM; Kwak, IS; Lee, JH, 2005) |
| "To observe the effects of continuous sedation with propofol on peripheral blood mononuclear cell (PBMC) and intercellular adhesion molecule 1 (ICAM-1) in beagles with combined burn-blast injuries." | 7.80 | [Effects of continuous sedation with propofol on peripheral blood mononuclear cell and intercellular adhesion molecule in beagles with combined burn-blast injuries]. ( Hou, Y; Hu, Q; Liu, L; Luo, H; Wang, Y; Yang, H, 2014) |
| "In operating theaters and burn units, propofol is commonly used for sedation and anesthesia in patients with major burns." | 7.76 | Population pharmacokinetics of a propofol bolus administered in patients with major burns. ( Han, TH; Kaneda, K; Yamashita, S, 2010) |
| "Propofol pharmacokinetics were examined in 17 adults with major burns during the hyperdynamic convalescent phase." | 7.75 | Propofol clearance and volume of distribution are increased in patients with major burns. ( Greenblatt, DJ; Han, TH; Martyn, JA, 2009) |
| "We gave propofol anesthesia to a patient with limb-girdle type of progressive muscular dystrophy." | 7.71 | [Propofol anesthesia for a patient with progressive muscular dystrophy]. ( Chikai, T; Egi, M; Fukushima, T; Ishizu, T; Kosogabe, Y; Tanaka, T; Tokioka, H, 2002) |
| "The use of propofol for repeated burns dressings in a severely psychologically disturbed child is described." | 7.68 | Propofol for repeated burns dressings in a child: a case report. ( Lord, WD; Mills, DC, 1992) |
| "No complete pharmacokinetic profile of propofol is yet available in children younger than 3 yr, whereas clinical studies have demonstrated that both induction and maintenance doses of propofol are increased with respect to body weight in this age group compared to older children and adults." | 5.29 | Pharmacokinetics of propofol after a single dose in children aged 1-3 years with minor burns. Comparison of three data analysis approaches. ( Billard, V; Farinotti, R; Marsol, P; Murat, I; Souron, R; Vernois, J; Zaouter, M, 1996) |
| "A total of 40 patients with severe burns with eschar excisions and skin grafts were randomly and equally grouped into the etomidate (E) and the propofol groups (P)." | 5.20 | Intraoperative target-controlled infusion anesthesia application using remifentanil hydrochloride with etomidate in patients with severe burn as monitored using Narcotrend. ( Guo, Z; Hao, J; Jia, X; Li, P; Mi, W; Pang, L; Su, X; Wang, X, 2015) |
| "This study evaluated the feasibility and effectiveness of using the bispectral index (BIS) to monitor anesthetic depth in patients with severe burns receiving intravenous target-controlled infusion (TCI) of remifentanil and propofol." | 5.20 | Bispectral index for monitoring anesthetic depth in patients with severe burns receiving target-controlled infusion of remifentanil and propofol. ( Guo, ZG; Hao, JH; Jia, XP; Li, P; Su, XJ; Wang, XY, 2015) |
| "In the burns group, significantly greater BIS values relating to increasing propofol TCI were noted at deeper anesthesia when compared with controls; at > or =3." | 5.11 | The relationship between bispectral index and targeted propofol concentration is biphasic in patients with major burns. ( Han, KW; Han, TH; Kil, HY; Kim, KM; Kwak, IS; Lee, JH, 2005) |
| " Within 48 h of admission, we compared total amounts of sedation/pain medications (morphine milligram equivalents (MME), propofol, dexmedetomidine, benzodiazepines) with total resuscitation volumes and frequency of hypotensive episodes." | 4.31 | The risks of sedation and pain control during burn resuscitation: Increased opioids lead to over-resuscitation and hypotension. ( Anderson, J; Mandell, SP; McClellan, JM; O'Neal, J; Sheckter, C; Stanton, E, 2023) |
| "To observe the effects of continuous sedation with propofol on peripheral blood mononuclear cell (PBMC) and intercellular adhesion molecule 1 (ICAM-1) in beagles with combined burn-blast injuries." | 3.80 | [Effects of continuous sedation with propofol on peripheral blood mononuclear cell and intercellular adhesion molecule in beagles with combined burn-blast injuries]. ( Hou, Y; Hu, Q; Liu, L; Luo, H; Wang, Y; Yang, H, 2014) |
| "To investigate the characteristics and differences of propofol pharmacokinetics in shock phase and hypermetabolic phase in severe burn in rabbits." | 3.76 | [Pharmacokinetics differences of propofol during different pathological stages of severe burn in rabbits]. ( Chai, JK; Hao, JH; Hu, QG; Li, MM; Li, P; Liu, S; Sun, XF; Yang, HM, 2010) |
| "We gave propofol anesthesia to a patient with limb-girdle type of progressive muscular dystrophy." | 3.71 | [Propofol anesthesia for a patient with progressive muscular dystrophy]. ( Chikai, T; Egi, M; Fukushima, T; Ishizu, T; Kosogabe, Y; Tanaka, T; Tokioka, H, 2002) |
| "The use of propofol for repeated burns dressings in a severely psychologically disturbed child is described." | 3.68 | Propofol for repeated burns dressings in a child: a case report. ( Lord, WD; Mills, DC, 1992) |
| "The sufentanil-propofol TCI was carried out during dressing changes." | 2.79 | Prediction of effect-site concentration of sufentanil by dose-response target controlled infusion of sufentanil and propofol for analgesic and sedation maintenance in burn dressing changes. ( Cao, D; Chen, L; Lin, X; Wang, M; Xiang, H; Ye, L, 2014) |
| "Application of Narcotrend monitor in monitoring the depth of anesthesia in severely burned patients during perioperative period with TCI of remifentanil hydrochloride and propofol is beneficial to reducing dosage of narcotics and shortening duration of recovery from anesthesia, and it can accurately predict the level of consciousness of patients at the time of withdrawal of anesthesia." | 2.77 | [Application of Narcotrend-assisted anesthesia in-depth monitor during escharectomy and skin transplantation in burn patients with target-controlled infusion of remifentanil hydrochloride and propofol]. ( Guo, ZG; Hao, JH; Lü, XL; Su, XJ; Wang, XY, 2012) |
| "Ketamine was the normal anaesthetic drug for carrying out the baths of severely burnt patients." | 2.66 | [Comparative trial of propofol and ketamine in anesthesia for the baths of severely burnt patients]. ( Cantineau, D; Crépy, A; Galizia, JP; Scherpereel, P; Selosse, A, 1987) |
| " Demographic and clinical data, including age, length of the procedure, recovery time, medication doses, and adverse events, were collected." | 1.91 | Safety and Efficacy of Propofol- and Ketamine-Based Procedural Sedation Regimen in Pediatric Patients During Burn Repetitive Dressing Change: 10 Years Single Center Experience. ( Abu-Sultaneh, S; Abulebda, K; Lutfi, R; Shieh Yu, J; Slaven, JE; Yabrodi, M, 2023) |
| "Propofol therapy was begun in combination with valproic acid, fluoxetine, and risperidone to assist in the treatment of his severe agitation associated with the bipolar disease, inhibiting ventilatory weaning." | 1.32 | Propofol withdrawal syndrome in an adult patient with thermal injury. ( Ackerman, BH; Cawley, MJ; Guse, TM; Haith, LR; Laroia, A, 2003) |
| "Ketamine was the most common agent for carrying out removal of adherent dressings." | 1.29 | [Propofol and ketamine for dressing in burnt patients]. ( Cantais, E; Dantzer, E; Escarment, J; Le Dantec, P; Palmier, B; Suppini, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 7 (21.21) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 13 (39.39) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Yabrodi, M | 1 |
| Shieh Yu, J | 1 |
| Slaven, JE | 1 |
| Lutfi, R | 1 |
| Abulebda, K | 1 |
| Abu-Sultaneh, S | 1 |
| McClellan, JM | 1 |
| Stanton, E | 1 |
| O'Neal, J | 1 |
| Anderson, J | 1 |
| Sheckter, C | 1 |
| Mandell, SP | 1 |
| Chen, L | 1 |
| Wang, M | 1 |
| Xiang, H | 1 |
| Lin, X | 1 |
| Cao, D | 1 |
| Ye, L | 1 |
| Guo, Z | 1 |
| Pang, L | 1 |
| Jia, X | 1 |
| Wang, X | 1 |
| Su, X | 1 |
| Li, P | 3 |
| Mi, W | 1 |
| Hao, J | 1 |
| Wang, Y | 1 |
| Yang, H | 1 |
| Hu, Q | 1 |
| Hou, Y | 1 |
| Luo, H | 1 |
| Liu, L | 1 |
| Seol, TK | 1 |
| Lim, JK | 1 |
| Yoo, EK | 1 |
| Min, SW | 1 |
| Kim, CS | 1 |
| Hwang, JY | 1 |
| Tian, KY | 1 |
| Liu, XJ | 1 |
| Xu, JD | 1 |
| Deng, LJ | 1 |
| Wang, G | 1 |
| Guo, ZG | 2 |
| Jia, XP | 1 |
| Wang, XY | 2 |
| Su, XJ | 2 |
| Hao, JH | 3 |
| Mahajan, R | 1 |
| Kassana, S | 1 |
| Jatinder, M | 1 |
| Nazir, R | 1 |
| Han, TH | 3 |
| Greenblatt, DJ | 1 |
| Martyn, JA | 1 |
| Tsukahara, Y | 1 |
| Ozawa, M | 1 |
| Joshita, S | 1 |
| Mochizuki, K | 1 |
| Kikuchi, T | 1 |
| Nitta, K | 1 |
| Dohgomori, H | 1 |
| Okamoto, K | 1 |
| Hu, QG | 1 |
| Chai, JK | 1 |
| Yang, HM | 1 |
| Sun, XF | 1 |
| Li, MM | 1 |
| Liu, S | 1 |
| Yamashita, S | 1 |
| Kaneda, K | 1 |
| Mazanikov, M | 1 |
| Pöyhiä, R | 1 |
| Rousseau, AF | 1 |
| Ledoux, D | 1 |
| Sabourdin, N | 1 |
| Richard, P | 1 |
| Damas, P | 1 |
| Constant, I | 1 |
| Lü, XL | 1 |
| Cawley, MJ | 1 |
| Guse, TM | 1 |
| Laroia, A | 1 |
| Haith, LR | 1 |
| Ackerman, BH | 1 |
| Coimbra, C | 1 |
| Choinière, M | 1 |
| Hemmerling, TM | 1 |
| Lee, JH | 1 |
| Kwak, IS | 1 |
| Kil, HY | 1 |
| Han, KW | 1 |
| Kim, KM | 1 |
| Yagmurdur, H | 2 |
| Yagmurder, H | 1 |
| Akca, G | 1 |
| Aksoy, M | 2 |
| Arslan, M | 2 |
| Baltaci, B | 2 |
| Dikmen, B | 1 |
| Tosun, Z | 1 |
| Esmaoglu, A | 1 |
| Coruh, A | 1 |
| Escarment, J | 1 |
| Cantais, E | 1 |
| Le Dantec, P | 1 |
| Suppini, A | 1 |
| Dantzer, E | 1 |
| Palmier, B | 1 |
| Bertin-Maghit, M | 1 |
| Gueugniaud, PY | 1 |
| Bouchard, C | 1 |
| Petit, P | 1 |
| Carsin, H | 1 |
| Murat, I | 1 |
| Billard, V | 1 |
| Vernois, J | 1 |
| Zaouter, M | 1 |
| Marsol, P | 1 |
| Souron, R | 1 |
| Farinotti, R | 1 |
| Egi, M | 1 |
| Tokioka, H | 1 |
| Chikai, T | 1 |
| Fukushima, T | 1 |
| Ishizu, T | 1 |
| Tanaka, T | 1 |
| Kosogabe, Y | 1 |
| Germain, JL | 1 |
| Bernasconi, C | 1 |
| Mills, DC | 1 |
| Lord, WD | 1 |
| Ivani, G | 1 |
| Della Rocca, M | 1 |
| de Negri, P | 1 |
| Galizia, JP | 2 |
| Imbenotte, M | 1 |
| Hochart, D | 1 |
| Zdzitowiecki, J | 1 |
| Erb, F | 1 |
| Scherpereel, P | 2 |
| Reyneke, CJ | 1 |
| James, MF | 1 |
| Johnson, R | 1 |
| Cantineau, D | 1 |
| Selosse, A | 1 |
| Crépy, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketofol Versus Fentofol for Procedural Sedation of Children 3 to 17 Years Old: a Double-Blind Randomized Controlled Trial[NCT02079090] | Phase 3 | 30 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 trials available for propofol and Burns
| Article | Year |
|---|---|
Prediction of effect-site concentration of sufentanil by dose-response target controlled infusion of sufentanil and propofol for analgesic and sedation maintenance in burn dressing changes.
Topics: Adult; Analgesics, Opioid; Bandages; Burns; Dose-Response Relationship, Drug; Feasibility Studies; F | 2014 |
Intraoperative target-controlled infusion anesthesia application using remifentanil hydrochloride with etomidate in patients with severe burn as monitored using Narcotrend.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Burns; Electroence | 2015 |
Propofol-ketamine or propofol-remifentanil for deep sedation and analgesia in pediatric patients undergoing burn dressing changes: a randomized clinical trial.
Topics: Analgesia; Anesthesia Recovery Period; Anesthetics, Dissociative; Anesthetics, Intravenous; Bandages | 2015 |
Bispectral index for monitoring anesthetic depth in patients with severe burns receiving target-controlled infusion of remifentanil and propofol.
Topics: Adult; Anesthesia; Anesthesia Recovery Period; Blood Pressure; Burns; Consciousness Monitors; Female | 2015 |
Clinical sedation and bispectral index in burn children receiving gamma-hydroxybutyrate.
Topics: Burns; Child; Child, Preschool; Conscious Sedation; Consciousness Monitors; Electroencephalography; | 2012 |
[Application of Narcotrend-assisted anesthesia in-depth monitor during escharectomy and skin transplantation in burn patients with target-controlled infusion of remifentanil hydrochloride and propofol].
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Burns; Female; Humans; Male; Middle Aged; Monitori | 2012 |
Patient-controlled sedation using propofol for dressing changes in burn patients: a dose-finding study.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Anxiety; Bandages; Burns; Conscious Sedation; D | 2003 |
The relationship between bispectral index and targeted propofol concentration is biphasic in patients with major burns.
Topics: Adult; Algorithms; Anesthetics, Intravenous; Burns; Critical Care; Electroencephalography; Female; H | 2005 |
Propofol-ketamine vs propofol-fentanyl combinations for deep sedation and analgesia in pediatric patients undergoing burn dressing changes.
Topics: Analgesia; Anesthetics, Dissociative; Anesthetics, Intravenous; Bandages; Blood Pressure; Burns; Chi | 2008 |
[Comparative trial of propofol and ketamine in anesthesia for the baths of severely burnt patients].
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthetics; Blood Pressure; Burns; Clinical Trials a | 1987 |
23 other studies available for propofol and Burns
| Article | Year |
|---|---|
Safety and Efficacy of Propofol- and Ketamine-Based Procedural Sedation Regimen in Pediatric Patients During Burn Repetitive Dressing Change: 10 Years Single Center Experience.
Topics: Bandages; Burns; Child; Child, Preschool; Humans; Hypnotics and Sedatives; Ketamine; Pain; Propofol; | 2023 |
The risks of sedation and pain control during burn resuscitation: Increased opioids lead to over-resuscitation and hypotension.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Burns; Dexmedetomidine; Fluid Therapy; Humans; Hypnotics | 2023 |
[Effects of continuous sedation with propofol on peripheral blood mononuclear cell and intercellular adhesion molecule in beagles with combined burn-blast injuries].
Topics: Animals; Apoptosis; Blast Injuries; Burns; Disease Models, Animal; Dogs; Hypnotics and Sedatives; In | 2014 |
Propofol inhibits burn injury-induced hyperpermeability through an apoptotic signal pathway in microvascular endothelial cells.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protei | 2015 |
Gum elastic bougie-guided insertion of laryngeal tube suction-II in patients with difficult airway.
Topics: Adult; Airway Management; Anesthesia, Inhalation; Anesthetics, Intravenous; Burns; Contracture; Dexm | 2016 |
Propofol clearance and volume of distribution are increased in patients with major burns.
Topics: Adult; Aged; Anesthetics, Intravenous; Burns; Case-Control Studies; Female; Humans; Male; Middle Age | 2009 |
[Anesthesia for a patient with morbid obesity, systemic edema and airway burn].
Topics: Adult; Anesthesia, Intravenous; Burns; Edema; Fentanyl; Humans; Intubation, Intratracheal; Laryngosc | 2010 |
[Pharmacokinetics differences of propofol during different pathological stages of severe burn in rabbits].
Topics: Animals; Burns; Propofol; Rabbits; Shock | 2010 |
Population pharmacokinetics of a propofol bolus administered in patients with major burns.
Topics: Administration, Oral; Adult; Aged; Burns; Drug Monitoring; Female; Humans; Hypnotics and Sedatives; | 2010 |
[Patient controlled sedation].
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Intravenous; Burns; Communication; C | 2011 |
Propofol withdrawal syndrome in an adult patient with thermal injury.
Topics: Bipolar Disorder; Burns; Ethanol; Fatal Outcome; Humans; Hypnotics and Sedatives; Male; Middle Aged; | 2003 |
The effects of ketamine and propofol on bacterial translocation in rats after burn injury.
Topics: Analgesics; Anesthetics, Intravenous; Animals; Bacterial Translocation; Blood Pressure; Burns; Disea | 2005 |
The effects of propofol and ketamine on gut mucosal epithelial apoptosis in rats after burn injury.
Topics: Animals; Apoptosis; Burns; Epithelial Cells; Intestinal Mucosa; Ketamine; Male; Malondialdehyde; Pro | 2007 |
[Propofol and ketamine for dressing in burnt patients].
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Burns; Child; Drug Combi | 1995 |
[Problems caused by anesthesia of patients with severe burns].
Topics: Anesthesia, General; Anesthetics; Balneology; Burns; Debridement; Humans; Intraoperative Care; Ketam | 1995 |
[Use of Diprivan in burn patients].
Topics: Anesthesia, Intravenous; Burns; Humans; Occlusive Dressings; Propofol; Skin Transplantation | 1994 |
Pharmacokinetics of propofol after a single dose in children aged 1-3 years with minor burns. Comparison of three data analysis approaches.
Topics: Age Factors; Anesthetics, Intravenous; Burns; Child, Preschool; Female; Humans; Infant; Male; Propof | 1996 |
[Propofol anesthesia for a patient with progressive muscular dystrophy].
Topics: Adult; Anesthesia, General; Burns; Humans; Male; Muscular Dystrophies; Propofol; Skin Transplantatio | 2002 |
[Combination of buprenorphine and propofol for the anesthesia of a burnt child].
Topics: Anesthesia, Intravenous; Buprenorphine; Burns; Child; Drug Combinations; Humans; Male; Propofol; Reo | 1992 |
Propofol for repeated burns dressings in a child: a case report.
Topics: Adolescent; Bandages; Burns; Humans; Ketamine; Male; Nutritional Status; Propofol; Skin Transplantat | 1992 |
[Anesthesia of the burned child].
Topics: Anesthesia, Intravenous; Burns; Child; Child, Preschool; Fentanyl; Humans; Propofol | 1990 |
[Pharmacokinetic study of propofol in burn patients].
Topics: Adult; Anesthetics; Burns; Humans; Propofol | 1989 |
Alfentanil and propofol infusions for surgery in the burned patient.
Topics: Adolescent; Adult; Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics; Bur | 1989 |