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propidium and Hypoxia

propidium has been researched along with Hypoxia in 24 studies

Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
" Ischemia-related damage was induced by OGD (5, 15, 45 min) or NMDA (10 microM) treatment, and was evaluated by measuring propidium iodide (PI) uptake."7.75Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: involvement of B-cell lymphoma 2 phosphorylation suppression. ( Cui, HS; Hori, H; Matsumoto, K; Murakami, Y; Obi, R; Zhao, Q, 2009)
" Ischemia-related damage was induced by OGD (5, 15, 45 min) or NMDA (10 microM) treatment, and was evaluated by measuring propidium iodide (PI) uptake."3.75Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: involvement of B-cell lymphoma 2 phosphorylation suppression. ( Cui, HS; Hori, H; Matsumoto, K; Murakami, Y; Obi, R; Zhao, Q, 2009)
"Etoposide, adriamycin, vinblastine, cisplatin and paclitaxel were able to induce apoptosis in human osteosarcoma cells SAOS-2 regardless of their anoikis resistance phenotype or the culture conditions (adhered vs."3.73Acquisition of anoikis resistance in human osteosarcoma cells does not alter sensitivity to chemotherapeutic agents. ( Díaz-Montero, CM; McIntyre, BW, 2005)
" The mitochondrial inhibitor antimycin A or hypoxia produced graded plasma membrane permeability in renal proximal tubules (RPTs), first allowing propidium iodide (PI, molecular mass 668 Da) influx and then lactate dehydrogenase (LDH, molecular mass 130 kDa) release."3.72Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death. ( Liu, X; Schnellmann, RG, 2003)
"Intralobular heterogeneity of mitochondrial dysfunction and its topographic relationship to cell death during 25% low-flow hypoxia was visually demonstrated in perfused rat hepatic microcirculatory units by dual-color digital microfluorography using rhodamine 123, a fluorochrome sensitive to the mitochondrial membrane potential, and propidium iodide, which labels the nuclei of nonviable cells with a concomitant enhancement of fluorescence."3.68Topographic dissociation between mitochondrial dysfunction and cell death during low-flow hypoxia in perfused rat liver. ( Hamamatsu, H; Ishii, H; Kato, S; Miura, S; Suematsu, M; Suzuki, H; Tsuchiya, M, 1992)
"Cells were exposed to anoxia (100% N2) and measurements of [Ca2+]i and cell survival made from 1 h to 18 h."1.33Intracellular calcium and survival of tadpole forebrain cells in anoxia. ( Bickler, PE; Fahlman, CS; Hedrick, MS, 2005)
"An important cause of anoxia-induced nerve injury involves the disruption of the ionic balance that exists across the neuronal membrane."1.30Anoxia-induced neuronal injury: role of Na+ entry and Na+-dependent transport. ( Chidekel, AS; Friedman, JE; Haddad, GG, 1997)
"Chemical anoxia was induced using 2."1.29Cell survival in rabbit gastric glands: effect of extracellular pH, osmolarity, and anoxia. ( Carter, KJ; Goddard, PJ; Lee, HH; Paimela, H; Silen, W; Yanaka, A, 1993)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (25.00)18.2507
2000's15 (62.50)29.6817
2010's3 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gu, XQ1
Pamenter, ME1
Siemen, D1
Sun, X1
Haddad, GG2
Cui, HS1
Matsumoto, K1
Murakami, Y1
Hori, H1
Zhao, Q1
Obi, R1
Radley, E1
Akram, A1
Grubb, BD1
Gibson, CL1
Shen, Y2
Sun, A1
Wang, Y1
Cha, D1
Wang, H1
Wang, F1
Feng, L1
Fang, S1
Liu, X1
Schnellmann, RG1
Cater, HL1
Chandratheva, A1
Benham, CD2
Morrison, B1
Sundstrom, LE2
Qiu, MH1
Zhang, R1
Sun, FY1
Bernas, T1
Zarebski, M1
Cook, RR1
Dobrucki, JW1
Cook, PR1
Hedrick, MS1
Fahlman, CS1
Bickler, PE1
Fogal, B1
Hewett, JA1
Hewett, SJ1
Díaz-Montero, CM1
McIntyre, BW1
Zou, S1
Li, L1
Pei, L1
Vukusic, B1
Van Tol, HH1
Lee, FJ1
Wan, Q1
Liu, F1
Cimarosti, H1
Zamin, LL1
Frozza, R1
Nassif, M1
Horn, AP1
Tavares, A1
Netto, CA1
Salbego, C1
de Pina-Benabou, MH1
Szostak, V1
Kyrozis, A1
Rempe, D1
Uziel, D1
Urban-Maldonado, M1
Benabou, S1
Spray, DC1
Federoff, HJ1
Stanton, PK1
Rozental, R1
Mulholland, PJ1
Stepanyan, TD1
Self, RL1
Hensley, AK1
Harris, BR1
Kowalski, A1
Littleton, JM1
Prendergast, MA1
Skibo, GG1
Lushnikova, IV1
Voronin, KY1
Dmitrieva, O1
Novikova, T1
Klementiev, B1
Vaudano, E1
Berezin, VA1
Bock, E1
Bonde, C1
Noraberg, J1
Noer, H1
Zimmer, J1
Raval, AP1
Bramlett, H1
Perez-Pinzon, MA1
Newell, DW1
Barth, A1
Papermaster, V1
Malouf, AT1
Zahrebelski, G1
Nieminen, AL1
al-Ghoul, K1
Qian, T1
Herman, B1
Lemasters, JJ1
Carter, KJ1
Lee, HH1
Goddard, PJ1
Yanaka, A1
Paimela, H1
Silen, W1
Chidekel, AS1
Friedman, JE1
Brana, C1
Suematsu, M1
Suzuki, H1
Ishii, H1
Kato, S1
Hamamatsu, H1
Miura, S1
Tsuchiya, M1

Other Studies

24 other studies available for propidium and Hypoxia

ArticleYear
Mitochondrial but not plasmalemmal BK channels are hypoxia-sensitive in human glioma.
    Glia, 2014, Volume: 62, Issue:4

    Topics: Adenosine Triphosphate; Calcium; Cell Line, Tumor; Cell Membrane; Charybdotoxin; Glioma; Humans; Hyp

2014
Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: involvement of B-cell lymphoma 2 phosphorylation suppression.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:1

    Topics: Animals; Berberine; Cell Death; Docosahexaenoic Acids; Excitatory Amino Acid Agonists; Glucose; Hipp

2009
Investigation of the mechanisms of progesterone protection following oxygen-glucose deprivation in organotypic hippocampal slice cultures.
    Neuroscience letters, 2012, Jan-06, Volume: 506, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Analysis of Variance; Animals; Animals, Newborn; Cell Death; Dose-Resp

2012
Upregulation of mesencephalic astrocyte-derived neurotrophic factor in glial cells is associated with ischemia-induced glial activation.
    Journal of neuroinflammation, 2012, Nov-23, Volume: 9

    Topics: Animals; Brain; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 3; Disease Models, Anima

2012
Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:1

    Topics: Acrylates; Actinin; Animals; Anti-Bacterial Agents; Antimycin A; Calpain; Cell Death; Cell Membrane

2003
Lactate and glucose as energy substrates during, and after, oxygen deprivation in rat hippocampal acute and cultured slices.
    Journal of neurochemistry, 2003, Volume: 87, Issue:6

    Topics: Amino Acids; Animals; Cell Hypoxia; Cell Survival; Dose-Response Relationship, Drug; Drug Interactio

2003
Enhancement of ischemia-induced tyrosine phosphorylation of Kv1.2 by vascular endothelial growth factor via activation of phosphatidylinositol 3-kinase.
    Journal of neurochemistry, 2003, Volume: 87, Issue:6

    Topics: Animals; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Survival; Cerebral Cortex; Drug Inter

2003
Minimizing photobleaching during confocal microscopy of fluorescent probes bound to chromatin: role of anoxia and photon flux.
    Journal of microscopy, 2004, Volume: 215, Issue:Pt 3

    Topics: Cells, Cultured; Chromatin; Chromomycin A3; Fibroblasts; Fluorescent Dyes; Green Fluorescent Protein

2004
Intracellular calcium and survival of tadpole forebrain cells in anoxia.
    The Journal of experimental biology, 2005, Volume: 208, Issue:Pt 4

    Topics: Analysis of Variance; Animals; Biological Transport, Active; Calcium; Cell Survival; Fluorescence; H

2005
Interleukin-1beta potentiates neuronal injury in a variety of injury models involving energy deprivation.
    Journal of neuroimmunology, 2005, Volume: 161, Issue:1-2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Ischemia; Cell Count; Cell Death; Cells, Cult

2005
Acquisition of anoikis resistance in human osteosarcoma cells does not alter sensitivity to chemotherapeutic agents.
    BMC cancer, 2005, Apr-13, Volume: 5

    Topics: Anoikis; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Sepa

2005
Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Apr-27, Volume: 25, Issue:17

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Blotting, Western; Bra

2005
Estradiol protects against oxygen and glucose deprivation in rat hippocampal organotypic cultures and activates Akt and inactivates GSK-3beta.
    Neurochemical research, 2005, Volume: 30, Issue:2

    Topics: Animals; Biotransformation; Blotting, Western; Cell Death; Enzyme Activation; Estradiol; Glucose; Gl

2005
Blockade of gap junctions in vivo provides neuroprotection after perinatal global ischemia.
    Stroke, 2005, Volume: 36, Issue:10

    Topics: Animals; Anti-Ulcer Agents; Apoptosis; Brain; Carbenoxolone; Caspase 3; Caspases; Cell Communication

2005
Corticosterone and dexamethasone potentiate cytotoxicity associated with oxygen-glucose deprivation in organotypic cerebellar slice cultures.
    Neuroscience, 2005, Volume: 136, Issue:1

    Topics: Animals; Antioxidants; Cell Death; Cerebellum; Chromans; Corticosterone; Dexamethasone; Drug Synergi

2005
A synthetic NCAM-derived peptide, FGL, protects hippocampal neurons from ischemic insult both in vitro and in vivo.
    The European journal of neuroscience, 2005, Volume: 22, Issue:7

    Topics: Animals; Animals, Newborn; Brain Ischemia; Cell Count; Cells, Cultured; Drug Interactions; Glucose;

2005
Ionotropic glutamate receptors and glutamate transporters are involved in necrotic neuronal cell death induced by oxygen-glucose deprivation of hippocampal slice cultures.
    Neuroscience, 2005, Volume: 136, Issue:3

    Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Ce

2005
Estrogen preconditioning protects the hippocampal CA1 against ischemia.
    Neuroscience, 2006, Sep-15, Volume: 141, Issue:4

    Topics: Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Cell Death; Chelating Agents; Do

2006
Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:11

    Topics: Animals; Fluorescence; Glucose; Hippocampus; Hypoxia; Organ Culture Techniques; Propidium; Rats; Rat

1995
Progression of subcellular changes during chemical hypoxia to cultured rat hepatocytes: a laser scanning confocal microscopic study.
    Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:5

    Topics: Animals; Cell Death; Cells, Cultured; Electrophysiology; Extracellular Space; Fluoresceins; Hypoxia;

1995
Cell survival in rabbit gastric glands: effect of extracellular pH, osmolarity, and anoxia.
    The American journal of physiology, 1993, Volume: 265, Issue:2 Pt 1

    Topics: Aminopyrine; Animals; Buffers; Cell Survival; Colforsin; Extracellular Space; Gastric Mucosa; Hydrog

1993
Anoxia-induced neuronal injury: role of Na+ entry and Na+-dependent transport.
    Experimental neurology, 1997, Volume: 146, Issue:2

    Topics: Amiloride; Animals; Bicarbonates; Biological Transport; Cell Nucleus; Cells, Cultured; Cerebral Cort

1997
Calpain activation and inhibition in organotypic rat hippocampal slice cultures deprived of oxygen and glucose.
    The European journal of neuroscience, 1999, Volume: 11, Issue:7

    Topics: Animals; Calpain; Coloring Agents; Cysteine Proteinase Inhibitors; Dipeptides; Glucose; Hippocampus;

1999
Topographic dissociation between mitochondrial dysfunction and cell death during low-flow hypoxia in perfused rat liver.
    Laboratory investigation; a journal of technical methods and pathology, 1992, Volume: 67, Issue:4

    Topics: Animals; Cell Death; Fluorescent Dyes; Fluorometry; Hypoxia; Liver Circulation; Male; Membrane Poten

1992