prazosin and Coma
prazosin has been researched along with Coma in 2 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, binding sites for the noradrenergic receptor subtype ligands, [3H]-prazosin (alpha1 sites), [3H]-RX821002 (alpha2 sites), and [125]I-iodopindolol (beta sites), were assessed using quantitative receptor autoradiography in regions of the brains of rats at coma stage of acute liver failure and of control groups of animals." | 3.70 | Evidence for altered central noradrenergic function in experimental acute liver failure in the rat. ( Butterworth, RF; Buu, PN; Michalak, A; Rose, C, 1998) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Jia, X | 1 |
| Yan, J | 1 |
| Xia, J | 1 |
| Xiong, J | 1 |
| Wang, T | 1 |
| Chen, Y | 1 |
| Qi, A | 1 |
| Yang, N | 1 |
| Fan, S | 1 |
| Ye, J | 1 |
| Hu, Z | 1 |
| Michalak, A | 1 |
| Rose, C | 1 |
| Buu, PN | 1 |
| Butterworth, RF | 1 |
Other Studies
2 other studies available for prazosin and Coma
| Article | Year |
|---|---|
Arousal effects of orexin A on acute alcohol intoxication-induced coma in rats.
Topics: Alcoholic Intoxication; Animals; Arousal; Benzoxazoles; Brain; Coma; Consciousness; Electroencephalo | 2012 |
Evidence for altered central noradrenergic function in experimental acute liver failure in the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Cerebral Cortex | 1998 |