piperaquine has been researched along with Malaria in 186 studies
*Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (8.06) | 18.7374 |
| 1990's | 3 (1.61) | 18.2507 |
| 2000's | 14 (7.53) | 29.6817 |
| 2010's | 99 (53.23) | 24.3611 |
| 2020's | 55 (29.57) | 2.80 |
| Authors | Studies |
|---|---|
| Ager, AL; Andersen, SL; Ellis, WY; Gerena, L; Milhous, WK; Vennerstrom, JL | 1 |
| Andrzejewski, C; Batty, KT; Ilett, KF; Jago, JD; Moore, BR; Page-Sharp, M | 1 |
| Becker, K; Davioud-Charvet, E; Friebolin, W; Furrer, J; Jannack, B; Lanzer, M; Oeser, T; Sanchez, CP; Wenzel, N; Yardley, V | 1 |
| Anstey, NM; Chalfein, F; Ebsworth, EP; Kenangalem, E; Marfurt, J; Piera, KA; Prasetyorini, B; Price, RN; Ratcliff, A; Russell, B; Siswantoro, H; Tjitra, E; Wuwung, M | 1 |
| Biamonte, MA; Le Roch, KG; Wanner, J | 1 |
| Bane, CE; Black, C; Butler, K; Caridha, D; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Huezo, SJ; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Nolan, C; Olmeda, R; Potter, B; Pou, S; Rasmussen, SA; Read, L; Riscoe, MK; Roncal, N; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Stephens, MT; Tan, JC; Vesely, B; Vuong, C; Winter, RW; Xie, L; Zeng, Q; Zhang, J; Zhang, P | 1 |
| Ashton, TD; Burrows, JN; Charman, SA; Creek, DJ; Devine, SM; Laleu, B; Möhrle, JJ; Sleebs, BE | 1 |
| Cheong, SL; Ng, CH; Tibon, NS | 1 |
| Bane, CE; Bayles, BR; Black, C; Butler, K; Caridha, D; Ceja, FG; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Mu, J; Nolan, C; Olmeda, R; Potter, B; Pou, S; Pybus, B; Rasmussen, SA; Read, L; Reynolds, KA; Riscoe, MK; Roncal, N; Rosenthal, PJ; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Tumwebaze, PK; Vesely, B; Vuong, C; Xie, L; Zeng, Q; Zhang, J; Zhang, P | 1 |
| Baguma, E; Boyce, RM; Brown-Marusiak, A; Goel, V; Hollingsworth, BD; Juliano, JJ; Muhindo, R; Mulogo, EM; Ntaro, M; Reyes, R; Siedner, MJ; Staedke, SG; Xu, E | 1 |
| Dimessa, LB; El Gaaloul, M; Esen, M; Garcia-Otero, L; González, R; Lagler, H; Lell, B; Menendez, C; Mischlinger, J; Mombo-Ngoma, G; Nhampossa, T; Piqueras, M; Pons-Duran, C; Ramharter, M; Sanz, S; Saute, F; Sevene, E; Tchouatieu, AM; Zoleko Manego, R | 1 |
| Aweeka, F; Clark, TD; Dorsey, G; Hughes, E; Jagannathan, P; Kajubi, R; Kakuru, A; Kamya, MR; Ochieng, T; Rosenthal, PJ; Savic, RM; Wallender, E | 1 |
| Achan, J; Bousema, T; Bradley, J; Broekhuizen, H; Ceesay, F; Conteh, B; D'Alessandro, U; Dabira, ED; Drakeley, C; Kandeh, B; Lindsay, SW; Mohammed, N; Ndiath, MO; Peeters Grietens, K; Slater, H; Smit, MR; Soumare, HM | 1 |
| Baraka, V; Kamugisha, E; Kapesa, A; Kidenya, B; Konje, E; Marwa, K; Mukonzo, J; Swedberg, G | 1 |
| Allen, E; Banda, CG; Barnes, KI; Chirwa, M; Kapulula, M; Maartens, G; Madanitsa, M; Munharo, S; Muyaya, S; Mwapasa, V; Nkosi, D; Phiri, KS; Ter Kuile, FO; Wiesner, L; Workman, L | 1 |
| Attaher, O; Bousema, T; Bradley, J; Diallo, M; Dicko, A; Dicko, OM; Drakeley, C; Issiaka, D; Keita, S; Lanke, K; Maguiraga, SO; Mahamar, A; McCall, MBB; Niambele, SM; Sacko, A; Samake, S; Sanogo, K; Sinaba, Y; Smit, MJ; Stone, W; Ter Heine, R; Traore, SF | 1 |
| Siahaan, L | 1 |
| Bruschi, F; Fabiani, S; L'Episcopia, M; Mangano, V; Motta, V; Severini, C; Sparavelli, R; Verdenelli, S | 1 |
| Abdallah, KS; Bacar, A; Deng, C; Li, G; Li, M; Liu, R; Lu, C; Silai, R; Song, J; Tan, R; Wu, W; Xu, Q; Yuan, Y; Zhang, H; Zheng, S | 1 |
| Buff, AM; Chebore, W; Desai, M; Kariuki, S; Otieno, K; Owidhi, M; Samuels, AM; Westercamp, N | 1 |
| Clapp, S; Freedman, B; Green, CL; Kirui, JK; Korwa, S; Njuguna, FM; O'Meara, WP; Taylor, SM; Wu, A | 1 |
| Cahyaningsih, U; Maring, AJ; Nugraha, AB; Sa'diah, S; Sari, RK; Syafii, W | 1 |
| Allen, E; Banda, CG; Barnes, KI; Chirwa, M; Kapulula, M; Maartens, G; Madanitsa, M; Munharo, S; Muyaya, S; Mwapasa, V; Nkosi, D; Phiri, KS; Tarning, J; Ter Kuile, FO; Workman, L | 1 |
| Bousema, T; Bradley, J; Camara, MM; Ceesay, S; Conteh, B; D'Alessandro, U; Dabira, ED; Drakeley, C; Erhart, A; Gaye, PM; Jadama, L; Jawara, EA; Kanteh, S; Lindsay, SW; Mohammed, N; Ndiath, MO; Njie, AK; Ooko, M; Sanneh, F; Soumare, HM | 1 |
| Assefa, A; Bekele, W; Chernet, M; Commons, RJ; Etana, K; Gidey, B; Girma, S; Gubae, K; Haile, M; Hailgiorgis, H; Mohammed, H; Sime, H; Solomon, H; Tasew, G; Tollera, G | 1 |
| Baraka, V; Chacky, F; Challe, DP; Chiduo, M; David, A; Francis, F; Gesase, S; Kamugisha, M; Lazaro, S; Liheluka, E; Lusasi, A; Lusingu, JPA; Makenga, G; Mandara, C; Mhina, A; Minja, DTR; Mmbando, BP; Mohamed, A; Molteni, F; Mtove, G; Nkayamba, A; Segeja, M; Seth, MD; Thawer, S; Van Geertruyden, JP | 1 |
| Abuaku, B; Amoako, EO; Asamoah, A; Boateng, P; Duah-Quashie, NO; Koram, KA; Malm, KL; Matrevi, SA; Owusu-Antwi, F; Peprah, NY; Quashie, N | 1 |
| Amoah, B; Bukenya, F; Colborn, K; Echodu, DC; Eganyu, T; Elliott, RC; Giorgi, E; Gonahasa, S; Kilama, M; Mulebeke, R; Nankabirwa, J; Odude, W; Omoding, O; Opigo, J; Powell, SE; Roskosky, M; Wanzira, H; Yeka, A | 1 |
| Akinola, O; Amusan, AI; Ategbero, E; Gbotosho, GO | 1 |
| Akun, P; Galileya, LT; Idro, R; Kalibbala, D; Nambatya, W; Nkosi-Gondwe, T; Opoka, R; Phiri, K; Robberstad, B; Rujumba, J; Ssenkusu, J; TerKuile, F | 1 |
| Chepngetich, J; Gachie, B; Gathirwa, J; Kiboi, D; Kimani, F; Magoma, G; Muriithi, B; Mwitari, P; Onchieku, N; Thiong'o, K | 1 |
| Baird, JK; Berni, A; Budiman, W; Cedar, E; Chand, K; Crenna-Darusallam, C; Duparc, S; Ekawati, LL; Elyazar, I; Fernando, D; Fletcher, K; Goyal, N; Green, JA; Instiaty, I; Jones, S; Kleim, JP; Lardo, S; Martin, A; Noviyanti, R; Prasetya, CB; Rolfe, K; Santy, YW; Satyagraha, AW; Sharma, H; Soebandrio, A; Subekti, D; Sutanto, I; Tan, LK; Taylor, M | 1 |
| Arcelia, F; Pasaribu, AP; Yanni, GN | 1 |
| Eisenberg, SL; Krieger, AE | 1 |
| Baraka, V; Francis, F; Geertruyden, JV; Gesase, S; Kyaruzi, E; Lusingu, JPA; Madebe, R; Makenga, G; Minja, DTR; Mtove, G; Nakato, S | 1 |
| Asih, PBS; Basri, HH; Bustos, MDG; Charunwatthana, P; Dewayanti, FK; Dondorp, AM; Imwong, M; Permana, DH; Prameswari, HD; Rahmasari, FV; Risandi, R; Rozi, IE; Syafruddin, D; Syahrani, L; Wangsamuda, S | 1 |
| Abebe, A; Ahmedin, M; Atim, MG; Embaye, SM; Kahabuka, M; Kazembe, D; Manyazewal, T; Mesfin, T; Muthoka, EN; Namuganza, S; Usmael, K | 1 |
| Bukenya, F; Collborn, K; Echodu, D; Eganyu, T; Elliot, R; Mulebeke, R; Van Geertruyden, JP; Wanzira, H; Yeka, A | 1 |
| Chandler, CIR; Dorsey, G; Drakeley, C; Gonahasa, S; Kamya, MR; Kigozi, SP; Maiteki-Sebuguzi, C; Okiring, J; Rehman, AM; Staedke, SG | 1 |
| Davidson, SA; Day, NPJ; Dondorp, A; Hanboonkunupakarn, B; Hoglund, RM; Jittamala, P; Kobylinski, KC; Mukaka, M; Pantuwatana, K; Phasomkusolsil, S; Pukrittayakamee, S; Tarning, J; van der Pluijm, RW; White, NJ; Winterberg, M | 1 |
| Ahmad, RA; Kenangalem, E; Laksono, IS; Lampah, DA; Murhandarwati, EEH; Poespoprodjo, JR; Sikora, SA; Sugiarto, P | 1 |
| Aljayyoussi, G; Alout, H; Bousema, T; Burrows, J; Chaccour, C; D'Alessandro, U; Foy, BD; Ghani, AC; Hellewell, J; Kobylinski, K; Slater, HC; Smit, MR; Ter Kuile, FO; Walker, PGT; Watson, OJ | 1 |
| D'Hoore, W; Kiguba, R; Kirabira, E; Manirakiza, L; Mukonzo, J; Nabirye, L; Ndagije, HB; Olsson, S; Speybroeck, N; Spinewine, A; Sserwanga, A | 1 |
| Abdulla, S; Adjei, A; Adjuik, M; Asante, KP; Baiden, R; Binka, F; Compaore, G; Day, NPJ; Gyapong, M; Kabanywanyi, AM; Macete, E; Oduro, A; Ogutu, B; Osei, I; Owusu-Agyei, S; Sevene, E; Sie, A; Tarning, J; Tinto, H; Valea, I; Wattanakul, T; White, NJ; Winterberg, M | 1 |
| Aide, P; Alonso, PL; Bassat, Q; Chidimatembue, A; Cisteró, P; Galatas, B; Gupta, H; Huijben, S; Matambisso, G; Mayor, A; Ménard, D; Nhamussua, L; Rabinovich, NR; Ringwald, P; Saúte, F; Simone, W | 1 |
| Desai, M; Dorsey, G; Fernandes, S; Gutman, J; Hanson, K; Kakuru, A; Kamya, MR; Kariuki, S; Ter Kuile, FO; Were, V | 1 |
| Ahmed, R; Ansariadi, A; Bonsapia, I; Burdam, FH; Hill, J; Khairallah, C; Paintain, L; Rini Poespoprodjo, J; Syafruddin, D; Ter Kuile, FO; Umbu Reku Landuwulang, C; Webster, J | 1 |
| Bruce, J; Desai, M; Hill, J; Kariuki, S; Oluoch, S; Ouma, P; Webster, J | 1 |
| Boele van Hensbroek, M; Desai, MR; Dhabangi, A; Idro, R; John, CC; Kariuki, S; Kuya, NA; Kwambai, TK; Onyango, ED; Opoka, R; Otieno, K; Phiri, KS; Robberstad, B; Samuels, AM; Ter Kuile, FO; Wang, D; Watson, V | 1 |
| Ahmed, R; Asih, PBS; Chotsiri, P; Desai, M; Gutman, JR; Kariuki, S; Katana, A; Khairallah, C; L'lanziva, A; Otieno, K; Ouma, P; Poespoprodjo, JR; Price, RN; Syafruddin, D; Tarning, J; Ter Kuile, FO; Were, V | 1 |
| Achan, J; D'Alessandro, U; de Vries, D; Grietens, KP; Gryseels, C; Jaiteh, F; Masunaga, Y; Okebe, J; Ribera, JM | 1 |
| Baker, M; Hoglund, RM; McCarthy, JS; McWhinney, B; Mohrle, J; Tarning, J; Wattanakul, T | 1 |
| Hafid, AF; Ilmi, H; Prasetyo, B; Tumewu, L; Widyawaruyanti, A | 1 |
| Akello, F; Amongi, S; Amongin, R; Cose, S; Elliott, AM; Kabuubi, PN; Kiwanuka, S; Kiwudhu, F; Kizindo, R; Mutebe, A; Nakazibwe, E; Nassuuna, J; Natukunda, A; Nkurunungi, G; Nsubuga, D; Oduru, G; Onen, C; Sewankambo, M; Staedke, SG; Webb, E; Zirimenya, L | 1 |
| Deng, C; Liang, Y; Lu, C; Song, J; Tan, B; Wang, Q; Wu, W; Xu, Q; Zhang, H; Zhou, C | 1 |
| Andersen, JF; Coonahan, ES; De Vos, M; Fay, MP; Long, CA; Pecic, S; Tarning, J; Wellems, TE; Yang, KA | 1 |
| Hughes, E; Jagannathan, P; Mohamed Ali, A; Savic, RM; Wallender, E | 1 |
| Aklillu, E; Kamuhabwa, AAR; Minzi, O; Mlugu, EM | 1 |
| Bancone, G; Carrara, VI; Chu, C; Duanguppama, J; Gilder, ME; Haohankhunnatham, W; Imwong, M; Konghahong, K; Lee, SJ; McGready, R; Min, AM; Nosten, F; Paw, MK; Phyo, AP; Pimanpanarak, M; Proux, S; Saito, M; Singhasivanon, P; Tun, NW; Turner, C; Viladpai-Nguen, J; White, NJ | 1 |
| Baltzell, K; Benjamin-Chung, J; Bhangu, K; Dlamini, B; Dlamini, N; Dufour, MK; Gosling, R; Greenhouse, B; Helb, D; Hsiang, MS; Kalungero, M; Kunene, S; Malambe, C; Maphalala, G; Mngadi, N; Nhlabathi, N; Ntshalintshali, N; Pindolia, D; Prach, LM; Tesfa, G; Vilakati, S; Whittemore, B | 1 |
| Andronescu, LR; Chinkhumba, J; Gutman, JR; Kachepa, W; Kachingwe, M; Laufer, MK; Liang, Y; Mathanga, DP; Peterson, I; Sharma, A | 1 |
| Hirai, M; Ikeda, M; Mita, T; Mori, T; Tachibana, SI | 1 |
| Esu, EB; Meremikwu, MM; Oringanje, C | 1 |
| Abega, F; Ayong, L; Berry, A; Gandia, P; Iriart, X; Khim, N; Lanot, T; Mairet-Khedim, M; Menard, S; Morlais, I; Ngou, C; Nsango, S; Otam, L; Roesch, C; Srun, S; Witkowski, B | 1 |
| Ategeka, J; Charlebois, ED; Clark, TD; Cohan, D; Dorsey, G; Havlir, DV; Jagannathan, P; Kakuru, A; Kamya, MR; Koss, CA; Muehlenbachs, A; Muhindo, M; Nakalembe, M; Natureeba, P; Nzarubara, B; Ochieng, T; Plenty, A; Rizzuto, G; Ruel, T | 1 |
| Delaval, P; Desrues, B; Fourmont, L; Jouneau, S; Lederlin, M; Polard, E; Revest, M; Tattevin, P | 1 |
| Buyze, J; D'Alessandro, U; Hachizovu, S; Kabuya, JB; Kasongo, W; Mulenga, J; Mulenga, M; Mwakazanga, D; Nambozi, M; Van Geertruyden, JP | 1 |
| Bouhenia, M; Coldiron, ME; Das, D; Elder, G; Grais, RF; Langendorf, C; Lasry, E; Mwanga, J; Nyehangane, D; Okui, P; Salumu, L | 1 |
| Affara, M; Bei, AK; Deme, AB; Dieye, B; Diongue, K; Gaye, A; Koita, O; Krogstad, DJ; Mbaye, A; Ndiaye, D; Ndiaye, IM; Ndiaye, T; Ndiaye, YD; Nwakanma, D; Sy, M; Sy, N; Volkman, S; Yade, MS | 1 |
| Clark, RL | 1 |
| Badhan, RKS; Coleman, M; Olafuyi, O | 1 |
| Aweeka, FT; Jagannathan, P; Kajubi, R | 1 |
| Srinivas, NR | 1 |
| Rabinovich, NR | 1 |
| Chandler, CIR; Dorsey, G; Drakeley, C; Gonahasa, S; Kamya, MR; Kigozi, SP; Lindsay, SW; Maiteki-Sebuguzi, C; Okiring, J; Rehman, AM; Staedke, SG | 1 |
| Bassat, Q; Millat-Martínez, P | 1 |
| Brugada, J; Chan, XHS; Mawer, LJ; Tan, JY; White, NJ; Win, YN | 1 |
| Kamara, ARY; Menard, D; Sahr, F; Samai, M; Smith, SJ; Swaray, AS; Warsame, M | 1 |
| Bernigaud, C; Chosidow, O; Do-Pham, G | 1 |
| Aol, G; Bigogo, GM; Desai, M; Hill, J; Laserson, KF; Phillips-Howard, PA; Taegtmeyer, M; Ter Kuile, F; Young, N | 1 |
| Blomberg, B; Gondwe, T; Lange, S; Mukaka, M; Phiri, K; Robberstad, B | 1 |
| Abong'o, BO; Aljayyoussi, G; Bayoh, NM; Bousema, T; Desai, MR; Gimnig, JE; Kariuki, SK; Kwambai, TK; Ochomo, EO; Phillips-Howard, PA; Samuels, AM; Smit, MR; Ter Kuile, FO; Wang, D; Ward, SA; Waterhouse, D | 1 |
| Cen, YZ; Deng, ZH; Li, XH; Liao, YB; Lin, RX; Liu, MR; Pan, B; Pei, FQ; Ren, WF; Ruan, CW | 1 |
| Abel, H; Bassat, Q; Ila, R; Karunajeewa, H; Laman, M; Manning, L; Millat-Martínez, P; Mitjà, O; Moore, B; Pulai, K; Robinson, L; Sanz, S | 1 |
| Guler, JL; Rosenthal, PJ | 1 |
| Achan, J; Affara, M; Bousema, T; D'Alessandro, U; di Tanna, GL; Dierickx, S; Drakeley, C; Kanuteh, F; Mohammed, NI; Mwesigwa, J; Nwakanma, D; Prom, A; Van Geertruyden, JP; Wathuo, M; Worwui, A | 1 |
| Desai, M; Dhabangi, A; Idro, R; John, CC; Kariuki, S; Kwambai, TK; Opoka, R; Phiri, K; Robberstad, B; Samuels, AM; Ter Kuile, FO; van Hensbroek, MB; Wang, D | 1 |
| Ali, AS; Ali, SM; Aydin-Schmidt, B; Bennett, A; Björkman, A; Hodzic, L; Islam, A; Jovel, I; Khamis, M; Magnusson, E; Mårtensson, A; Mkali, H; Morris, U; Msellem, MI; Poirot, E; Sachs, MC; Shija, SJ; Tarning, J | 1 |
| Blomberg, B; Lange, S; Nkosi-Gondwe, T; Phiri, KS; Robberstad, B | 1 |
| Bangirana, P; Conroy, AL; Dorsey, G; Jagannathan, P; John, CC; Kakuru, A; Kamya, MR; Liechty, EA; Muhindo, MK; Nakalembe, M; Opoka, RO | 1 |
| Beavogui, AH; Borghini-Fuhrer, I; Djimdé, AA; Duparc, S; Felices, M; Funck-Brentano, C; Khan, Y; Ouedraogo, JB; Ouologuem, N; Sagara, I; Sirima, SB; Soulama, I; Voiriot, P | 1 |
| Balen, J; Bradley, J; D'Alessandro, U; Grietens, KP; Gryseels, C; Jaiteh, F; Masunaga, Y; Okebe, J; Ribera, JM | 1 |
| Hakizimana, D; Kabera, M; Kayobotsi, C; Mbituyumuremyi, A; Munyaneza, T; Murindahabi, M; Musanabaganwa, C; Muvunyi, CM; Nisingizwe, MP; Ntagwabira, E; Penkunas, MJ; Umulisa, N; Uwimana, A; Uyizeye, D; Warsame, M | 1 |
| Laufer, MK | 1 |
| Chau Ngo, TM; Dinh Huynh, C; Fiori, PL; Giang Phan, TH; Hanh Nguyen, TL; Hoang, H; Low, PS; Marchetti, G; Pantaleo, A; Pau, MC; Schwarzer, E; Ton Nu, PA; Tsamesidis, I; Tuan Tran, A; Turrini, FM | 1 |
| Esu, E; Meremikwu, M; Oduwole, O; Okusanya, BO; Olaleye, A | 1 |
| Garrido Jareño, M; Otero Reigada, MDC; Peman García, J; Ramírez Cuentas, JH; Roselló Guijarro, M; Urtasun Erburu, A | 1 |
| Cohee, LM; Laufer, MK | 1 |
| Guo, H; Huang, X; Lu, F; Ye, Z; Yi, G; Zhou, L | 1 |
| Cano, J; Chico, RM | 1 |
| Arinaitwe, E; Aweeka, FT; Bigira, V; Creek, DJ; Kakuru, A; Lindegardh, N; McCormack, S; Nosten, F; Parikh, S; Sandison, TG; Tappero, JW; Wanzira, H | 1 |
| Poll, EM; Ubben, D | 1 |
| Ariey, F; Beck, HP; Buclin, T; Csajka, C; Decosterd, LA; Duong, S; Genton, B; Guidi, M; Kabanywanyi, AM; Mercier, T; Olliaro, P; Staehli Hodel, EM; Zanolari, B | 1 |
| Doua, JY; Lutumba, P; Matangila, J; Van Geertruyden, JP | 1 |
| Amuge, P; Brooker, SJ; Dorsey, G; Kamya, MR; Kiwanuka, N; Nankabirwa, JI; Rosenthal, PJ; Staedke, SG; Wandera, B | 1 |
| Hastings, IM; Hayes, DJ; Hodel, EM; Kay, K; Terlouw, DJ | 1 |
| Borrmann, S; Pfeil, J; Tozan, Y | 1 |
| Achan, J; Arinaitwe, E; Charlebois, E; Clark, TD; Dorsey, G; Havlir, D; Ikilezi, G; Kakuru, A; Kamya, MR; Muhindo, MK; Mwangwa, F; Rosenthal, PJ; Ruel, T; Tappero, JW | 1 |
| Batty, KT; Gibbons, PL; Kirkpatrick, CM; Moore, BR; Patel, K | 1 |
| Batty, KT; Benjamin, JM; Davis, TM; Ginny, E; Griffin, S; Moore, BR; Mueller, I; Page-Sharp, M; Robinson, LJ; Salman, S; Siba, P | 1 |
| Auayporn, M; Buathong, N; Cantilena, L; Chann, S; Chour, CM; Haigney, M; Kaewkungwal, J; Kuntawunginn, W; Lanteri, C; Lon, C; Manning, J; Mitprasat, M; Phann, ST; Prom, S; Saunders, D; Se, Y; Sea, D; Siripokasupkul, R; So, M; Soh, E; Somethy, S; Spring, M; Sriwichai, S; Tang, D; Teja-Isavadharm, P; Timmermans, A; Vanachayangkul, P | 1 |
| Achan, J; Aweeka, FT; Bigira, V; Clark, TD; Dorsey, G; Havlir, DV; Huang, L; Kamya, MR; Kapisi, J; Kinara, S; Muhindo, MK; Mwangwa, F; Osterbauer, B; Rosenthal, PJ | 1 |
| Borrmann, S; Heiss, K; Meister, M; Mueller, AK; Pfeil, J; Sepp, KJ | 1 |
| Mori, AT; Ngalesoni, F; Norheim, OF; Robberstad, B | 1 |
| Bergstrand, M; Karlsson, MO; Lwin, KM; Nosten, F; Tarning, J; White, NJ | 1 |
| Achan, J; Aweeka, FT; Bigira, V; Clark, TD; Dorsey, G; Havlir, DV; Huang, L; Jagannathan, P; Kakuru, A; Kamya, MR; Kapisi, J; Kinara, S; Muhindo, MK; Mwangwa, F; Rosenthal, PJ | 1 |
| Claeys, Y; D'Alessandro, U; De Crop, M; Halidou, T; Kalanda, G; Menten, J; Mulenga, M; Mutabingwa, T; Mwakazanga, D; Mwapasa, V; Nambozi, M; Phiri, LK; Ravinetto, R; Schurmans, C; Tagbor, H; Thriemer, K; Traore, M; Valea, I; Van Geertruyden, JP | 1 |
| Ewing, VL; Kapinda, A; Lalloo, DG; Pace, C; Richards, E; Terlouw, DJ; Tolhurst, R | 1 |
| Burugu, MW; Gimode, WR; Kiboi, DM; Kimani, FT; Muregi, FW; Wamakima, HN | 1 |
| Arinaitwe, E; Aweeka, FT; Bigira, V; Creek, DJ; Kakuru, A; Lindegardh, N; McCormack, SA; Nosten, F; Parikh, S; Sambol, NC; Tappero, JW; Tarning, J; Wanzira, H; Yan, L | 1 |
| Abdulla, S; Adjei, A; Adjuik, M; Akparibo, R; Baiden, R; Binka, F; Compaoré, G; Gyapong, M; Halidou, T; Macete, E; Mulokozi, A; Oduro, A; Ogutu, B; Osei, I; Owusu-Agyei, S; Sevene, E; Sie, A; Smith, P; Upunda, GL; Valea, I; Yawson, A | 1 |
| Compaore, YD; Greenwood, B; Milligan, P; Nosten, F; Ouedraogo, JB; Rosenthal, PJ; Some, AF; Sutherland, C; Tarning, J; Zongo, I | 1 |
| Anstey, NM; Fobia, W; Kenangalem, E; Lampah, DA; Poespoprodjo, JR; Price, RN; Sugiarto, P; Tjitra, E | 1 |
| Casteras, J; Dhingra, SK; Fidock, DA; Gabryszewski, SJ; Legrand, E; Moss, EL; Musset, L; Neafsey, DE; Pelleau, S; Volkman, SK; Volney, B; Wirth, DF | 1 |
| Bennett, A; Chalwe, V; Eisele, TP; Finn, T; Hamainza, B; Kamuliwo, M; Keating, J; Miller, JM; Moonga, H; Silumbe, K; Steketee, RW; Yukich, J | 1 |
| Aweeka, F; Bigira, V; Dorsey, G; Huang, L; Jagannathan, P; Kakuru, MM; Kamya, MR; Kapisi, J; Savic, R; Sundell, K | 1 |
| Desai, M; Gutman, J; Juma, E; Kariuki, S; Katana, A; L'lanziva, A; Laserson, K; Otieno, K; Ouma, P; ter Kuile, FO; Were, V; Williamson, J | 1 |
| Mori, AT; Norheim, OF; Robberstad, B | 1 |
| Acheampong, PR; Antwi, GD; Bart Plange, C; Cairns, M; Chandramohan, D; Tagbor, H | 1 |
| Anvikar, AR; Arora, S; Iyer, SS; Jalali, RK; Mishra, P; Rao, BS; Roy, A; Rulisa, S; Saha, N; Sharma, P; Toure, OA; Valecha, N | 1 |
| Anvikar, AR; Arora, S; Gogtay, N; Iyer, SS; Jalali, RK; Kochar, SK; Kumar, NB; Lakhani, JD; Rajadhyaksha, GC; Rao, BH; Roy, A; Saha, N; Savargaonkar, D; Sharma, P; Solanki, BB; Srivastava, B; Tripathi, SK; Valecha, N | 1 |
| Abdulla, S; Adjei, A; Adjuik, M; Amu, A; Asante, KP; Baiden, R; Binka, F; Compaore, G; Gyapong, M; Halidou, T; Kukula, V; Macete, E; Mulokozi, A; Nagai, RA; Narh-Bana, S; Oduro, A; Ogutu, B; Osei, I; Owusu-Agyei, S; Sevene, E; Sie, A; Valea, I | 1 |
| Bannister-Tyrell, M; D'Alessandro, U; Dierickx, S; Gerrets, R; Grietens, KP; Gryseels, C; Jaiteh, F; Mwesigwa, J; O'Neill, S; Ronse, M | 1 |
| Maxmen, A | 1 |
| Ategeka, J; Awori, P; Charlebois, ED; Clark, TD; Dorsey, G; Feeney, ME; Havlir, DV; Jagannathan, P; Kakuru, A; Kamya, MR; Muehlenbachs, A; Muhindo, MK; Nakalembe, M; Natureeba, P; Nayebare, P; Olwoch, P; Opira, B; Rizzuto, G | 1 |
| Achieng, F; Desai, M; Hill, J; Hoyt, J; Kariuki, S; L'lanziva, A; Ouma, P; Webster, J | 1 |
| Arinaitwe, E; Parikh, S; Sambol, NC; Tappero, JW | 1 |
| Ali, D; Faragher, B; Kalilani, L; Kang'ombe, A; Khairallah, C; Levitt, B; Madanitsa, M; Meshnick, S; Mwapasa, V; Pace, C; Smedley, J; Taylor, SM; Ter Kuile, FO; Thwai, KL; van Eijk, AM; Wang, D | 1 |
| Elvina, E; Kajeechiwa, L; Kyawt, K; Min, JR; Nosten, F; Nosten, S; Oo, PT; Peapah, P; PoWah, W; Shee, PW; Thwin, MM; von Seidlein, L; Wiladphaingern, J; Yee, NL | 1 |
| Abdulla, S; Adjei, A; Adjuik, M; Akparibo, R; Ali, AM; Baiden, R; Binka, F; Compaoré, G; Gyapong, M; Kabanywanyi, AM; Kakolwa, MA; Macete, E; Mahende, MK; Oduro, A; Ogutu, BR; Osei, I; Owusu-Agyei, S; Sevene, E; Sie, A; Tinto, H; Valea, I; Yawson, A | 1 |
| Dorsey, G; Gutman, J; Kovacs, S; Stergachis, A; Ter Kuile, FO | 1 |
| Sullivan, DJ; Walker, LA | 1 |
| da Luz, RI; Doua, JY; Lutumba, P; Matangila, JR; Mitashi, P; Van Geertruyden, JP | 1 |
| Aweeka, FT; Chamankhah, N; Dorsey, G; Havlir, D; Huang, L; Jagannathan, P; Kajubi, R; Kakuru, A; Kamya, M; Koss, CA; Mwebaza, N; Rosenthal, PJ; Ruel, T; Were, M | 1 |
| Dorsey, G; Nosten, F; Price, RN | 1 |
| Abiodun, O; Bell, A; Brun, R; Chollet, J; Irungu, BN; Kiboi, DM; Langat, B; Nganga, JK; Nyambati, VC; Nzila, A; Rukunga, GM; Wittlin, S | 1 |
| Batty, KT; Ilett, KF; Jago, JD; Moore, BR; Page-Sharp, M | 1 |
| Donegan, S; Garner, P; Olliaro, P; Sinclair, D; Zani, B | 1 |
| D'alessandro, U | 1 |
| Cairns, M; Cames, C; Cheng, Y; Cisse, B; Faye, B; Faye, E; Faye, O; Gaye, O; Greenwood, B; Lô, AC; Milligan, P; NDiaye, JL; NDiaye, M; NDiaye, O; Simondon, K; Trape, JF | 1 |
| Bacchieri, A; Bassat, Q; Borrmann, S; Corsi, M; D'Alessandro, U; Menéndez, C; Mulenga, M; Nabasumba, C; Nambozi, M; Piola, P; Sasi, P; Talisuna, A; Tinto, H; Ubben, D; Valéa, I | 1 |
| Arinaitwe, E; Bigira, V; Creek, D; Dorsey, G; Kakuru, A; Kamya, MR; Sandison, TG; Tappero, J; Wanzira, H | 1 |
| Arinaitwe, E; Bigira, V; Dorsey, G; Kakuru, A; Kamya, M; Sandison, T; Tappero, JW; Verret, WJ; Wanzira, H | 1 |
| Adjalley, SH; Eappen, AG; Eastman, RT; Ekland, EH; Fidock, DA; Hoffman, SL; Johnston, GL; Lee, MC; Li, T; Richman, A; Sim, BK | 1 |
| Day, NP; Hanpithakpong, W; Lindegardh, N; McGready, R; Nosten, F; Phyo, AP; Rijken, MJ; Tarning, J; White, NJ | 1 |
| Batty, KT; Davis, TM; Griffin, S; Ilett, KF; Kose, K; Mueller, I; Page-Sharp, M; Salman, S; Siba, PM | 1 |
| Amansyah, F; Dedang, TA; Driyah, S; Ekowatiningsih, R; Hasugian, AR; Januar, L; Labora, J; Prasetyorini, B; Purnama, A; Purnamasari, T; Salwati, E; Siswantoro, H; Tjitra, E; Wijayanto, B; Yusnita, EA; Yuwarni, E | 1 |
| Chavchich, M; Dai, B; Edstein, MD; Phong, NC; Quang, HH; Shanks, GD; Thanh, NX; Trung, TN | 1 |
| D'Alessandro, U; Donegan, S; Tudur Smith, C; Williamson, P | 1 |
| Guo, H; Huang, XX; Pan, ZY; Wu, JY; Xue, WL; Yi, GH; Zhou, LM | 1 |
| Aung, K; Mak, JW; Naing, C; Wong, JY | 1 |
| Ariey, F; Beck, HP; Csajka, C; Decosterd, LA; Duong, S; Genton, B; Guidi, M; Kabanywanyi, AM; Olliaro, P; Staehli Hodel, EM | 1 |
| Baird, JK; Basri, H; Ekawati, LL; Elyazar, I; Farrar, J; Meilia, RA; Nurleila, S; Putri, FA; Setiabudy, R; Sudoyo, H; Sutanto, I; Taylor, WR; Tjahjono, B | 1 |
| Davis, TM; Hung, TY; Ilett, KF; Karunajeewa, HA; Sim, IK | 1 |
| Chollet, J; Santo-Tomas, J; Scheurer, C; Snyder, C; Wittlin, S | 1 |
| Anstey, NM; Ebsworth, EP; Hasugian, AR; Kenangalem, E; Laihad, F; Lindegardh, N; Penttinen, P; Price, RN; Purba, HL; Ratcliff, A; Siswantoro, H; Tjitra, E | 1 |
| Lindegardh, N; Tarning, J | 1 |
| Coulanges, P; Deloron, P; Le Bras, J; Ramanamirija, JA; Verdier, P | 1 |
| Coulanges, P; Deloron, P; Ramanamirija, JA; Verdíer, F | 1 |
| Coulanges, P; Deĺoron, P; Le Bras, J; Ramanamirija, JA | 2 |
| Dai, ZR; Jiang, ZK; Li, JC; Zhu, DQ | 1 |
| Qu, FY | 1 |
| Chen, L; Qu, FY; Zhou, YC | 1 |
| Chen, C; Chen, L; Dai, ZR; Ma, ZM; Zheng, XY | 1 |
| Chen, L; Li, G; Lu, Y; Luo, Z | 1 |
| Chen, L | 1 |
| Chen, L; Dai, ZR; Fu, DD; Guo, FC; Liao, ZH; Ma, DQ; Ma, ZM; Pang, XJ; Qian, YL | 1 |
| Chen, YS; Guo, RN; Huang, ZS; Lan, CX; Lin, X | 1 |
| Fu, LC; Guo, XB | 1 |
| Chen, L; Dai, ZR; Li, CJ; Qian, YL | 1 |
| Biaud, JM; Coulanges, P; Deloron, P; Le Bras, J; Ramanamirija, JA | 1 |
| Li, GD | 1 |
| Huang, JZ; Lan, XH; Xu, WZ | 1 |
| Wu, Z | 1 |
17 review(s) available for piperaquine and Malaria
| Article | Year |
|---|---|
Recent advances in malaria drug discovery.
Topics: Animals; Antimalarials; Drug Discovery; Humans; Liver; Liver Transplantation; Malaria; Molecular Structure | 2013 |
The Development Process for Discovery and Clinical Advancement of Modern Antimalarials.
Topics: Antimalarials; Drug Discovery; Humans; Malaria; Molecular Structure; Plasmodium | 2019 |
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines | 2020 |
Therapeutic efficacy of artemether-lumefantrine, artesunate-amodiaquine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Sub-Saharan Africa: A systematic review and meta-analysis.
Topics: Africa South of the Sahara; Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Humans; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines | 2022 |
Therapeutic efficacy of dihydroartemisinin-piperaquine combination for the treatment of uncomplicated malaria in Ghana.
Topics: Antimalarials; Child; Drug Combinations; Ghana; Humans; Malaria; Malaria, Falciparum; Parasitemia; Treatment Outcome | 2022 |
Safety and tolerability of repeated doses of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnancy: a systematic review and an aggregated data meta-analysis of randomized controlled trials.
Topics: Antimalarials; Drug Combinations; Female; Humans; Infant; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Randomized Controlled Trials as Topic; Sulfadoxine; Vomiting | 2023 |
Malaria PK/PD and the Role Pharmacometrics Can Play in the Global Health Arena: Malaria Treatment Regimens for Vulnerable Populations.
Topics: Amodiaquine; Anti-HIV Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child, Preschool; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Global Health; HIV Infections; Humans; Malaria; Malnutrition; Mefloquine; Models, Biological; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Vulnerable Populations | 2021 |
Intermittent preventive treatment for malaria in infants.
Topics: Africa South of the Sahara; Amodiaquine; Antimalarials; Artemisinins; Bias; Confidence Intervals; Disease Eradication; Drug Combinations; Endemic Diseases; Hospitalization; Humans; Infant; Malaria; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2021 |
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens | 2017 |
Risk of sudden unexplained death after use of dihydroartemisinin-piperaquine for malaria: a systematic review and Bayesian meta-analysis.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Bayes Theorem; Cause of Death; Cohort Studies; Drug Therapy, Combination; Female; Humans; Malaria; Mozambique; Prospective Studies; Quinolines | 2018 |
A systematic review and meta-analysis of dihydroartemisinin-piperaquine versus sulphadoxine-pyrimethamine for malaria prevention in pregnancy.
Topics: Adult; Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria; Parasitemia; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Care; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2019 |
Safety, tolerability, and efficacy of repeated doses of dihydroartemisinin-piperaquine for prevention and treatment of malaria: a systematic review and meta-analysis.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2017 |
Artemisinin-based combination therapy for treating uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Pyrimethamine; Quinolines; Randomized Controlled Trials as Topic; Sulfadoxine | 2009 |
Progress in the development of piperaquine combinations for the treatment of malaria.
Topics: Adult; Antimalarials; Artemisinins; Child; Clinical Trials as Topic; Drug Combinations; Humans; Malaria; Quinolines | 2009 |
Efficacy and safety of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum malaria in endemic countries: meta-analysis of randomised controlled studies.
Topics: Antimalarials; Artemisinins; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Quinolines; Randomized Controlled Trials as Topic; Treatment Failure | 2013 |
Piperaquine: a resurgent antimalarial drug.
Topics: Animals; Antimalarials; Humans; Malaria; Quinolines | 2005 |
Quantification of the antimalarial piperaquine in plasma.
Topics: Animals; Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria; Quinolines; Tandem Mass Spectrometry | 2008 |
67 trial(s) available for piperaquine and Malaria
| Article | Year |
|---|---|
Dihydroartemisinin-Piperaquine Chemoprevention and Malaria Incidence After Severe Flooding: Evaluation of a Pragmatic Intervention in Rural Uganda.
Topics: Adult; Antimalarials; Artemisinins; Chemoprevention; Child; Floods; Humans; Incidence; Malaria; Piperazines; Quinolines; Uganda | 2022 |
Evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women: protocol of a multicentre, two-arm, randomised, placebo-controlled, superiority clinical trial (MAMAH
Topics: Antimalarials; Artemisinins; Drug Combinations; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Malaria; Multicenter Studies as Topic; Pregnancy; Pregnancy Complications, Parasitic; Pregnant Women; Quinolines; Randomized Controlled Trials as Topic | 2021 |
Piperaquine-Induced QTc Prolongation Decreases With Repeated Monthly Dihydroartemisinin-Piperaquine Dosing in Pregnant Ugandan Women.
Topics: Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Piperazines; Placenta; Pregnancy; Pregnant Women; Quinolines; Uganda | 2022 |
Effect of dihydroartemisinin/piperaquine for malaria intermittent preventive treatment on dolutegravir exposure in pregnant women living with HIV.
Topics: Adult; Antimalarials; Artemisinins; Drug Combinations; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Malaria; Oxazines; Piperazines; Pregnancy; Pregnancy Complications, Parasitic; Pregnant Women; Pyridones; Quinolines | 2022 |
Single low-dose tafenoquine combined with dihydroartemisinin-piperaquine to reduce Plasmodium falciparum transmission in Ouelessebougou, Mali: a phase 2, single-blind, randomised clinical trial.
Topics: Aminoquinolines; Animals; Artemisinins; Humans; Malaria; Malaria, Falciparum; Mali; Piperazines; Plasmodium falciparum; Quinolines; Single-Blind Method | 2022 |
Artemisinin-piperaquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Grande Comore island: an open-label, non-randomised controlled trial.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines | 2022 |
Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled trial.
Topics: Amodiaquine; Anemia, Sickle Cell; Antimalarials; Artemisinins; Chemoprevention; Child; Child, Preschool; Drug Combinations; Female; Humans; Hydroxyurea; Infant; Kenya; Malaria; Malaria, Falciparum; Male; Proguanil; Pyrimethamine; Sulfadoxine | 2022 |
Impact of Dolutegravir-Based Antiretroviral Therapy on Piperaquine Exposure following Dihydroartemisinin-Piperaquine Intermittent Preventive Treatment of Malaria in Pregnant Women Living with HIV.
Topics: Antimalarials; Female; HIV Infections; Humans; Malaria; Pregnancy; Pregnant Women; Quinolines | 2022 |
Entomological impact of mass administration of ivermectin and dihydroartemisinin-piperaquine in The Gambia: a cluster-randomized controlled trial.
Topics: Adult; Animals; Anopheles; Artemisinins; Gambia; Humans; Ivermectin; Malaria; Mass Drug Administration; Mosquito Vectors | 2022 |
Implementation research of a cluster randomized trial evaluating the implementation and effectiveness of intermittent preventive treatment for malaria using dihydroartemisinin-piperaquine on reducing malaria burden in school-aged children in Tanzania: met
Topics: Antimalarials; Child; Drug Combinations; Humans; Malaria; Quinolines; Tanzania | 2023 |
Impact of population based indoor residual spraying with and without mass drug administration with dihydroartemisinin-piperaquine on malaria prevalence in a high transmission setting: a quasi-experimental controlled before-and-after trial in northeastern
Topics: Adolescent; Child; Cross-Sectional Studies; Humans; Insecticides; Malaria; Mass Drug Administration; Mosquito Control; Prevalence; Uganda | 2023 |
Dihydroartemisinin-piperaquine or sulphadoxine-pyrimethamine for the chemoprevention of malaria in children with sickle cell anaemia in eastern and southern Africa (CHEMCHA): a protocol for a multi-centre, two-arm, double-blind, randomised, placebo-contro
Topics: Africa, Southern; Anemia, Sickle Cell; Antimalarials; Chemoprevention; Child; Drug Combinations; Humans; Malaria; Multicenter Studies as Topic; Quinolines; Randomized Controlled Trials as Topic | 2023 |
Tafenoquine co-administered with dihydroartemisinin-piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Malaria, Vivax; Plasmodium vivax; Primaquine; Quinolines | 2023 |
Effectiveness and safety of intermittent preventive treatment with dihydroartemisinin-piperaquine or artesunate-amodiaquine for reducing malaria and related morbidities in schoolchildren in Tanzania: a randomised controlled trial.
Topics: Amodiaquine; Antimalarials; Artesunate; Child; COVID-19; Drug Combinations; Hemoglobins; Humans; Incidence; Malaria; Malaria, Falciparum; Quinolines; Tanzania | 2023 |
Intermittent preventive treatment of malaria delivered to primary schoolchildren provided effective individual protection in Jinja, Uganda: secondary outcomes of a cluster-randomized trial (START-IPT).
Topics: Adolescent; Anemia; Antimalarials; Artemisinins; Child; Child, Preschool; Cluster Analysis; Drug Combinations; Female; Humans; Malaria; Male; Prevalence; Quinolines; Students; Uganda | 2019 |
Cost-effectiveness of intermittent preventive treatment with dihydroartemisinin-piperaquine versus single screening and treatment for the control of malaria in pregnancy in Papua, Indonesia: a provider perspective analysis from a cluster-randomised trial.
Topics: Adult; Antimalarials; Artemisinins; Cluster Analysis; Cost-Benefit Analysis; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Indonesia; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Quinolines | 2020 |
Malaria Chemoprevention in the Postdischarge Management of Severe Anemia.
Topics: Aftercare; Anemia; Antimalarials; Artemisinins; Child, Preschool; Drug Combinations; Endemic Diseases; Female; Humans; Infant; Kenya; Malaria; Male; Patient Readmission; Quinolines; Uganda | 2020 |
Effect of intermittent preventive treatment for malaria with dihydroartemisinin-piperaquine on immune responses to vaccines among rural Ugandan adolescents: randomised controlled trial protocol B for the '
Topics: Adolescent; Antimalarials; Artemisinins; Drug Combinations; Humans; Immunity; Malaria; Quinolines; Randomized Controlled Trials as Topic; Uganda | 2021 |
Effectiveness of Intermittent Preventive Treatment With Dihydroartemisinin-Piperaqunine Against Malaria in Pregnancy in Tanzania: A Randomized Controlled Trial.
Topics: Adult; Antimalarials; Artemisinins; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Quinolines; Single-Blind Method; Tanzania; Treatment Outcome; Young Adult | 2021 |
A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in pregnancy on the Thailand-Myanmar border.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Malaria; Malaria, Falciparum; Mefloquine; Myanmar; Pregnancy; Premature Birth; Quinolines; Thailand | 2021 |
Effectiveness and safety of reactive focal mass drug administration (rfMDA) using dihydroartemisinin-piperaquine to reduce malaria transmission in the very low-endemic setting of Eswatini: a pragmatic cluster randomised controlled trial.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Eswatini; Humans; Malaria; Mass Drug Administration; Quinolines | 2021 |
The Effect of Intermittent Preventive Treatment of Malaria During Pregnancy and Placental Malaria on Infant Risk of Malaria.
Topics: Adult; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Infant; Malaria; Malawi; Parasitemia; Piperazines; Placenta; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Treatment Outcome | 2022 |
Intermittent Preventive Treatment With Dihydroartemisinin-Piperaquine for the Prevention of Malaria Among HIV-Infected Pregnant Women.
Topics: Adult; Antimalarials; Artemisinins; Double-Blind Method; Endpoint Determination; Female; Follow-Up Studies; HIV Infections; Humans; Incidence; Malaria; Pregnancy; Pregnancy Complications, Infectious; Quinolines; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda; Young Adult | 2017 |
Artemisinin-based combination therapy in pregnant women in Zambia: efficacy, safety and risk of recurrent malaria.
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Malaria; Mefloquine; Pregnancy; Quinolines; Recurrence; Risk; Treatment Outcome; Young Adult; Zambia | 2017 |
Pyronaridine-artesunate or dihydroartemisinin-piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Longitudinal Studies; Malaria; Male; Naphthyridines; Quinolines; Young Adult | 2018 |
Assessment of community-level effects of intermittent preventive treatment for malaria in schoolchildren in Jinja, Uganda (START-IPT trial): a cluster-randomised trial.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Cluster Analysis; Cross-Sectional Studies; Drug Administration Schedule; Drug Combinations; Female; Health Surveys; Humans; Malaria; Male; Prevalence; Quinolines; Residence Characteristics; School Health Services; Treatment Outcome; Uganda; Young Adult | 2018 |
Delivery strategies for malaria chemoprevention with monthly dihydroartemisinin-piperaquine for the post-discharge management of severe anaemia in children aged less than 5 years old in Malawi: a protocol for a cluster randomized trial.
Topics: Anemia; Antimalarials; Artemisinins; Child, Preschool; Drug Administration Schedule; Humans; Infant; Malaria; Malawi; Medication Adherence; Quinolines | 2018 |
Pharmacokinetics-Pharmacodynamics of High-Dose Ivermectin with Dihydroartemisinin-Piperaquine on Mosquitocidal Activity and QT-Prolongation (IVERMAL).
Topics: Adult; Animals; Anopheles; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Interactions; Female; Humans; Insecticides; Ivermectin; Kenya; Long QT Syndrome; Malaria; Male; Quinolines; Treatment Outcome | 2019 |
Malaria chemoprevention with monthly dihydroartemisinin-piperaquine for the post-discharge management of severe anaemia in children aged less than 5 years in Uganda and Kenya: study protocol for a multi-centre, two-arm, randomised, placebo-controlled, sup
Topics: Anemia; Artemisinins; Chemoprevention; Child, Preschool; Double-Blind Method; Drug Combinations; Humans; Infant; Infant, Newborn; Kenya; Malaria; Multicenter Studies as Topic; Quinolines; Randomized Controlled Trials as Topic; Sample Size; Uganda | 2018 |
A cluster randomised controlled trial of two rounds of mass drug administration in Zanzibar, a malaria pre-elimination setting-high coverage and safety, but no significant impact on transmission.
Topics: Antimalarials; Artemisinins; Female; Humans; Incidence; Malaria; Male; Mass Drug Administration; Prevalence; Primaquine; Quinolines; Tanzania | 2018 |
Introducing post-discharge malaria chemoprevention (PMC) for management of severe anemia in Malawian children: a qualitative study of community health workers' perceptions and motivation.
Topics: Anemia; Antimalarials; Artemisinins; Attitude of Health Personnel; Caregivers; Chemoprevention; Child; Child, Preschool; Community Health Workers; Drug Combinations; Feasibility Studies; Female; Focus Groups; Government Programs; House Calls; Humans; Infant; Inservice Training; Malaria; Malawi; Male; Motivation; Patient Discharge; Perception; Qualitative Research; Quinolines; Workload | 2018 |
Community perspectives on treating asymptomatic infections for malaria elimination in The Gambia.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Asymptomatic Infections; Child; Child, Preschool; Cross-Sectional Studies; Disease Eradication; Female; Gambia; Humans; Infant; Infant, Newborn; Malaria; Male; Patient Acceptance of Health Care; Quinolines; Young Adult | 2019 |
Efficacy of artemether-lumefantrine versus dihydroartemisinin-piperaquine for the treatment of uncomplicated malaria among children in Rwanda: an open-label, randomized controlled trial.
Topics: Adolescent; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Female; Humans; Infant; Malaria; Male; Quinolines; Rwanda | 2019 |
Pharmacokinetic predictors for recurrent malaria after dihydroartemisinin-piperaquine treatment of uncomplicated malaria in Ugandan infants.
Topics: Antimalarials; Artemisinins; Chemoprevention; Female; Follow-Up Studies; Humans; Infant; Malaria; Male; Plasma; Prospective Studies; Quinolines; Secondary Prevention; Time Factors; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 2013 |
Intermittent preventive treatment: efficacy and safety of sulfadoxine-pyrimethamine and sulfadoxine-pyrimethamine plus piperaquine regimens in schoolchildren of the Democratic Republic of Congo: a study protocol for a randomized controlled trial.
Topics: Antimalarials; Child; Clinical Protocols; Congo; Drug Combinations; Drug Therapy, Combination; Ethics, Medical; Humans; Malaria; Pyrimethamine; Quinolines; Research Design; Sample Size; Sulfadoxine | 2013 |
Impact of intermittent preventive treatment with dihydroartemisinin-piperaquine on malaria in Ugandan schoolchildren: a randomized, placebo-controlled trial.
Topics: Anemia; Antimalarials; Artemisinins; Child; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Male; Parasitemia; Prevalence; Quinolines; Risk Factors; Uganda | 2014 |
Artemisinin-based combination therapies are efficacious and safe for treatment of uncomplicated malaria in HIV-infected Ugandan children.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lopinavir; Malaria; Male; Nevirapine; Parasitemia; Quinolines; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Uganda | 2014 |
Effect of coadministered fat on the tolerability, safety, and pharmacokinetic properties of dihydroartemisinin-piperaquine in Papua New Guinean children with uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Child; Female; Hemodynamics; Humans; Malaria; Male; Quinolines | 2014 |
Randomized, double-blind, placebo-controlled clinical trial of a two-day regimen of dihydroartemisinin-piperaquine for malaria prevention halted for concern over prolonged corrected QT interval.
Topics: Adult; Antimalarials; Arrhythmias, Cardiac; Artemisinins; Double-Blind Method; Female; Humans; Malaria; Male; Quinolines; Young Adult | 2014 |
Protective efficacy and safety of three antimalarial regimens for the prevention of malaria in young Ugandan children: a randomized controlled trial.
Topics: Antimalarials; Artemisinins; Cohort Studies; Drug Combinations; Female; Humans; Incidence; Infant; Malaria; Male; Pyrimethamine; Quinolines; Sulfadoxine; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 2014 |
Characterization of an in vivo concentration-effect relationship for piperaquine in malaria chemoprevention.
Topics: Antimalarials; Humans; Malaria; Male; Placebos; Quinolines; Thailand | 2014 |
Efficacy and safety of three regimens for the prevention of malaria in young HIV-exposed Ugandan children: a randomized controlled trial.
Topics: Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Cohort Studies; Drug Combinations; Female; Humans; Infant; Malaria; Male; Pyrimethamine; Quinolines; Sulfadoxine; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 2014 |
Safe and efficacious artemisinin-based combination treatments for African pregnant women with malaria: a multicentre randomized control trial.
Topics: Adult; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Birth Weight; Burkina Faso; Drug Combinations; Ethanolamines; Female; Fetal Development; Fluorenes; Follow-Up Studies; Ghana; Humans; Infant, Newborn; Malaria; Malawi; Mefloquine; Placentation; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Exposure Delayed Effects; Quinolines; Zambia | 2015 |
Perceptions and utilization of the anti-malarials artemether-lumefantrine and dihydroartemisinin-piperaquine in young children in the Chikhwawa District of Malawi: a mixed methods study.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Drug Combinations; Drug Utilization; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria; Malawi; Male; Medication Adherence; Quinolines; Surveys and Questionnaires | 2015 |
Randomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina Faso.
Topics: Amodiaquine; Antimalarials; Artemisinins; Burkina Faso; Case-Control Studies; Chemoprevention; Child, Preschool; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Pyrimethamine; Quinolines; Seasons; Sulfadoxine | 2015 |
Assessing the effectiveness of household-level focal mass drug administration and community-wide mass drug administration for reducing malaria parasite infection prevalence and incidence in Southern Province, Zambia: study protocol for a community randomi
Topics: Antimalarials; Artemisinins; Catchment Area, Health; Child, Preschool; Community Health Services; Cross-Sectional Studies; Drug Combinations; Health Facilities; Humans; Incidence; Infant; Longitudinal Studies; Malaria; Mass Screening; Prevalence; Program Evaluation; Quinolines; Research Design; Seasons; Time Factors; Treatment Outcome; Zambia | 2015 |
Variable piperaquine exposure significantly impacts protective efficacy of monthly dihydroartemisinin-piperaquine for the prevention of malaria in Ugandan children.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Chemoprevention; Child, Preschool; Disease Transmission, Infectious; Female; Humans; Infant; Malaria; Male; Quinolines; Random Allocation; Treatment Outcome; Uganda; Young Adult | 2015 |
Intermittent screening and treatment or intermittent preventive treatment with dihydroartemisinin-piperaquine versus intermittent preventive treatment with sulfadoxine-pyrimethamine for the control of malaria during pregnancy in western Kenya: an open-lab
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Drug Combinations; Drug Therapy, Combination; Female; Humans; Kenya; Malaria; Mass Screening; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Diagnosis; Pyrimethamine; Quinolines; Risk Factors; Sulfadoxine; Treatment Outcome; Young Adult | 2015 |
Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Chemoprevention; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Ghana; Humans; Infant; Infant, Newborn; Lumefantrine; Malaria; Male; Pyrimethamine; Quinolines; Rain; Seasons; Sulfadoxine | 2016 |
Efficacy and safety of fixed dose combination of arterolane maleate and piperaquine phosphate dispersible tablets in paediatric patients with acute uncomplicated Plasmodium falciparum malaria: a phase II, multicentric, open-label study.
Topics: Antimalarials; Child; Child, Preschool; Cote d'Ivoire; Drug Combinations; Female; Heterocyclic Compounds, 1-Ring; Humans; India; Infant; Infant, Newborn; Malaria; Malaria, Falciparum; Male; Peroxides; Plasmodium falciparum; Quinolines; Rwanda; Spiro Compounds; Tablets | 2015 |
Comparison of the safety and efficacy of fixed-dose combination of arterolane maleate and piperaquine phosphate with chloroquine in acute, uncomplicated Plasmodium vivax malaria: a phase III, multicentric, open-label study.
Topics: Adolescent; Adult; Aged; Antimalarials; Chloroquine; Drug Therapy, Combination; Female; Heterocyclic Compounds, 1-Ring; Humans; Malaria; Malaria, Vivax; Male; Maleates; Middle Aged; Peroxides; Quinolines; Spiro Compounds; Young Adult | 2016 |
Dihydroartemisinin-Piperaquine for the Prevention of Malaria in Pregnancy.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Resistance; Female; Humans; Incidence; Malaria; Parasitemia; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pyrimethamine; Quinolines; Sulfadoxine; Uganda; Vomiting; Young Adult | 2016 |
User and Provider Acceptability of Intermittent Screening and Treatment and Intermittent Preventive Treatment with Dihydroartemisinin-Piperaquine to Prevent Malaria in Pregnancy in Western Kenya.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Female; Humans; Kenya; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Quinolines; Young Adult | 2016 |
Scheduled Intermittent Screening with Rapid Diagnostic Tests and Treatment with Dihydroartemisinin-Piperaquine versus Intermittent Preventive Therapy with Sulfadoxine-Pyrimethamine for Malaria in Pregnancy in Malawi: An Open-Label Randomized Controlled Tr
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Diagnostic Tests, Routine; Drug Combinations; Female; Humans; Malaria; Malawi; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinolines; Sulfadoxine; Young Adult | 2016 |
Efficacy and safety of intermittent preventive treatment in schoolchildren with sulfadoxine/pyrimethamine (SP) and SP plus piperaquine in Democratic Republic of the Congo: a randomised controlled trial.
Topics: Adolescent; Anemia; Antimalarials; Chemoprevention; Child; Child, Preschool; Democratic Republic of the Congo; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Hemoglobins; Humans; Malaria; Male; Parasitemia; Pyrimethamine; Quinolines; Schools; Students; Sulfadoxine; Treatment Outcome | 2017 |
Antiretroviral Therapy With Efavirenz Accentuates Pregnancy-Associated Reduction of Dihydroartemisinin-Piperaquine Exposure During Malaria Chemoprevention.
Topics: Adolescent; Adult; Alkynes; Antimalarials; Area Under Curve; Artemisinins; Benzoxazines; Chemoprevention; Cyclopropanes; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Female; HIV Infections; Humans; Malaria; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Complications, Parasitic; Quinolines; Reverse Transcriptase Inhibitors; Uganda; Young Adult | 2017 |
Randomized trial of piperaquine with sulfadoxine-pyrimethamine or dihydroartemisinin for malaria intermittent preventive treatment in children.
Topics: Antimalarials; Artemisinins; Child, Preschool; Cluster Analysis; Drug Combinations; Female; Humans; Incidence; Infant; Malaria; Male; Pyrimethamine; Quinolines; Rural Population; Senegal; Sulfadoxine; Treatment Outcome | 2009 |
Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial.
Topics: Africa; Antiparasitic Agents; Artemether; Artemisinins; Child, Preschool; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Infant; Lumefantrine; Malaria; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Time Factors | 2009 |
Increased risk of early vomiting among infants and young children treated with dihydroartemisinin-piperaquine compared with artemether-lumefantrine for uncomplicated malaria.
Topics: Antimalarials; Artemether; Artemisinins; Child, Preschool; Ethanolamines; Fluorenes; Humans; Infant; Lumefantrine; Malaria; Quinolines; Risk; Uganda; Vomiting | 2010 |
Effect of nutritional status on response to treatment with artemisinin-based combination therapy in young Ugandan children with malaria.
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Infant; Malaria; Malnutrition; Parasitemia; Quinolines | 2011 |
Pharmacokinetic comparison of two piperaquine-containing artemisinin combination therapies in Papua New Guinean children with uncomplicated malaria.
Topics: Antimalarials; Artemisinins; Child; Child, Preschool; Female; Humans; Malaria; Male; Quinolines | 2012 |
Efficacy and safety of artemisinin-naphthoquine versus dihydroartemisinin-piperaquine in adult patients with uncomplicated malaria: a multi-centre study in Indonesia.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; DNA, Protozoan; Female; Humans; Indonesia; Malaria; Male; Middle Aged; Naphthoquinones; Parasitemia; Polymerase Chain Reaction; Quinolines; Treatment Outcome; Young Adult | 2012 |
The efficacy and tolerability of artemisinin-piperaquine (Artequick®) versus artesunate-amodiaquine (Coarsucam™) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam.
Topics: Adolescent; Adult; Amodiaquine; Animals; Artemisinins; Blood; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Polymerase Chain Reaction; Quinolines; Time Factors; Treatment Outcome; Vietnam; Young Adult | 2012 |
Randomized, open-label trial of primaquine against vivax malaria relapse in Indonesia.
Topics: Adult; Antimalarials; Artemisinins; Artesunate; Drug Administration Schedule; Drug Dosage Calculations; Drug Resistance; Drug Therapy, Combination; Humans; Indonesia; Malaria; Malaria, Vivax; Male; Military Personnel; Plasmodium vivax; Primaquine; Quinine; Quinolines; Secondary Prevention | 2013 |
Clinical and pharmacological determinants of the therapeutic response to dihydroartemisinin-piperaquine for drug-resistant malaria.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Indonesia; Infant; Malaria; Male; Middle Aged; Prospective Studies; Quinolines; Sesquiterpenes; Survival Analysis; Treatment Outcome | 2007 |
[Observation on the efficacy of combined use of some new antimalarials for the treatment of falciparum malaria in Hainan Province].
Topics: Adolescent; Adult; Animals; Antimalarials; Drug Therapy, Combination; Female; Humans; Malaria; Male; Naphthyridines; Plasmodium falciparum; Quinazolines; Quinolines | 1989 |
[Comparative study of artemisinin suppositories and piperaquine phosphate in the treatment of falciparum malaria].
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Child; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinolines; Sesquiterpenes; Suppositories | 1989 |
102 other study(ies) available for piperaquine and Malaria
| Article | Year |
|---|---|
Bisquinolines. 1. N,N-bis(7-chloroquinolin-4-yl)alkanediamines with potential against chloroquine-resistant malaria.
Topics: Animals; Antimalarials; Chloroquine; Cyclohexylamines; Drug Resistance; Malaria; Molecular Conformation; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 1992 |
Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model.
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Therapy, Combination; Humans; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Quinolines; Sesquiterpenes; Treatment Outcome | 2008 |
Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum.
Topics: Animals; Antimalarials; Biological Transport; Cell Line, Tumor; Chloroquine; Drug Resistance; Drug Therapy, Combination; Glutathione Reductase; Humans; In Vitro Techniques; Malaria; Mice; Mice, Inbred BALB C; Naphthalenes; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship | 2008 |
In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Female; Humans; Indonesia; Malaria; Male; Middle Aged; Plasmodium malariae; Plasmodium ovale; Treatment Outcome; Young Adult | 2011 |
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Topics: Acridones; Animals; Antimalarials; Disease Models, Animal; Drug Discovery; Hep G2 Cells; Humans; Malaria; Mice; Plasmodium; Species Specificity; Structure-Activity Relationship | 2019 |
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
Topics: Acridones; Administration, Oral; Animals; Antimalarials; Cell Survival; Disease Models, Animal; Female; Half-Life; Hep G2 Cells; Humans; Life Cycle Stages; Malaria; Male; Mice; Mice, Inbred C57BL; Plasmodium falciparum; Structure-Activity Relationship | 2020 |
Mass drug administration of ivermectin and dihydroartemisinin-piperaquine against malaria in settings with high coverage of standard control interventions: a cluster-randomised controlled trial in The Gambia.
Topics: Animals; Antimalarials; Artemisinins; Gambia; Humans; Ivermectin; Malaria; Mass Drug Administration; Mosquito Vectors; Piperazines; Quinolines | 2022 |
Observation of Malaria Treatment with Dihydroartemisinin-Piperaquine Combination at Primary Health Care
Topics: Antimalarials; Artemisinins; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Piperazines; Primary Health Care; Quinolines; Treatment Outcome | 2022 |
Artesunate and dihydroartemisinin-piperaquine treatment failure in a severe Plasmodium falciparum malaria case imported from Republic of Côte d'Ivoire.
Topics: Aged; Antimalarials; Artemisinins; Artesunate; Cote d'Ivoire; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Male; Piperazines; Plasmodium falciparum; Quinolines; Treatment Failure | 2022 |
Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria among Children in Western Kenya, 2016 to 2017.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Combinations; Ethanolamines; Fluorenes; Folic Acid Antagonists; Humans; Infant; Kenya; Malaria; Malaria, Falciparum; Piperazines; Plasmodium falciparum; Quinolines; Reinfection | 2022 |
Antimalarial Efficacy of Aqueous Extract of Strychnos ligustrina and Its Combination with Dihydroartemisinin and Piperaquine Phosphate (DHP) against Plasmodium berghei Infection.
Topics: Animals; Antimalarials; Artemisinins; Malaria; Mice; Mice, Inbred BALB C; Phosphates; Plant Extracts; Plasmodium berghei; Strychnos | 2022 |
Therapeutic efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium vivax malaria in Seacha area, Arbaminch Zuria District, South West Ethiopia.
Topics: Antimalarials; Artemisinins; Ethiopia; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax | 2022 |
Comparative efficacy of sulphadoxine-pyrimethamine and dihydroartemisinin-piperaquine against malaria infection during late-stage pregnancy in mice.
Topics: Animals; Antimalarials; Drug Combinations; Drug Therapy, Combination; Female; Malaria; Malaria, Falciparum; Mice; Plasmodium berghei; Pregnancy; Pyrimethamine | 2023 |
Prevalence of mutations in the cysteine desulfurase IscS (Pfnfs1) gene in recurrent Plasmodium falciparum infections following artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) treatment in Matayos, Western Kenya.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Drug Combinations; Humans; Kenya; Lumefantrine; Malaria; Malaria, Falciparum; Mutation; Plasmodium falciparum; Prevalence; Quinolines; Reinfection | 2023 |
Effectiveness of dihydroartemisinin-piperaquine after 10 years as treatment for vivax malaria in Indonesia.
Topics: Adult; Antimalarials; Child; Humans; Indonesia; Malaria; Malaria, Falciparum; Malaria, Vivax; Prospective Studies | 2023 |
A comprehensive approach to optimizing malaria prevention in pregnant women: evaluating the efficacy, cost-effectiveness, and resistance of IPTp-SP and IPTp-DP.
Topics: Antimalarials; Cost-Benefit Analysis; Female; Humans; Malaria; Pregnancy; Pregnant Women | 2023 |
Evolution of genetic markers for drug resistance after the introduction of dihydroartemisinin-piperaquine as first-line anti-malarial treatment for uncomplicated falciparum malaria in Indonesia.
Topics: Antimalarials; DNA Copy Number Variations; Drug Resistance; Genetic Markers; Humans; Indonesia; Malaria; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins | 2023 |
Implementing population-based mass drug administration for malaria: experience from a high transmission setting in North Eastern Uganda.
Topics: Antimalarials; Artemisinins; Community Participation; Drug Combinations; Malaria; Mass Drug Administration; Quinolines; Uganda | 2019 |
Safety, Pharmacokinetics, and Mosquito-Lethal Effects of Ivermectin in Combination With Dihydroartemisinin-Piperaquine and Primaquine in Healthy Adult Thai Subjects.
Topics: Adolescent; Adult; Animals; Anopheles; Antimalarials; Artemisinins; Drug Interactions; Drug Therapy, Combination; Female; Humans; Insecticides; Ivermectin; Malaria; Male; Middle Aged; Primaquine; Quinolines; Thailand; Young Adult | 2020 |
Intravenous artesunate plus oral dihydroartemisinin-piperaquine or intravenous quinine plus oral quinine for optimum treatment of severe malaria: lesson learnt from a field hospital in Timika, Papua, Indonesia.
Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Female; Humans; Indonesia; Infant; Infant, Newborn; Malaria; Male; Middle Aged; Quinine; Quinolines; Retrospective Studies; Young Adult | 2019 |
Ivermectin as a novel complementary malaria control tool to reduce incidence and prevalence: a modelling study.
Topics: Animals; Antimalarials; Artemisinins; Burkina Faso; Child; Female; Humans; Incidence; Insecticides; Ivermectin; Malaria; Male; Mass Drug Administration; Mosquito Vectors; Prevalence; Quinolines; Randomized Controlled Trials as Topic; Seasons | 2020 |
Healthcare professionals' perspective can guide post-marketing surveillance of artemisinin-based combination therapy in Uganda.
Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Cross-Sectional Studies; Drug Resistance; Drug Therapy, Combination; Female; Health Personnel; Humans; Logistic Models; Malaria; Male; Patient Compliance; Plasmodium falciparum; Product Surveillance, Postmarketing; Quinolines; Sesquiterpenes; Surveys and Questionnaires; Tablets; Treatment Failure; Uganda | 2020 |
Pooled Multicenter Analysis of Cardiovascular Safety and Population Pharmacokinetic Properties of Piperaquine in African Patients with Uncomplicated Falciparum Malaria.
Topics: Africa; Antimalarials; Child; Humans; Malaria; Malaria, Falciparum; Quinolines | 2020 |
Effect of mass dihydroartemisinin-piperaquine administration in southern Mozambique on the carriage of molecular markers of antimalarial resistance.
Topics: Antimalarials; Artemisinins; Drug Combinations; Drug Resistance; Malaria; Mozambique; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinolines | 2020 |
Cost-effectiveness of intermittent preventive treatment with dihydroartemisinin-piperaquine for malaria during pregnancy: an analysis using efficacy results from Uganda and Kenya, and pooled data.
Topics: Adult; Antimalarials; Artemisinins; Cost-Benefit Analysis; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Kenya; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Quinolines; Therapeutics; Uganda; Young Adult | 2020 |
Intermittent screening and treatment with dihydroartemisinin-piperaquine for the prevention of malaria in pregnancy: implementation feasibility in a routine healthcare system setting in western Kenya.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Diagnostic Tests, Routine; Drug Combinations; Feasibility Studies; Female; Humans; Kenya; Malaria; Mass Screening; Middle Aged; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Care; Quinolines; Young Adult | 2020 |
Piperaquine Pharmacokinetics during Intermittent Preventive Treatment for Malaria in Pregnancy.
Topics: Antimalarials; Drug Combinations; Female; Humans; Indonesia; Kenya; Malaria; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Quinolines | 2021 |
Understanding adherence to reactive treatment of asymptomatic malaria infections in The Gambia.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Asymptomatic Infections; Child; Child, Preschool; Female; Gambia; Humans; Infant; Infant, Newborn; Malaria; Male; Medication Adherence; Patient Compliance; Plasmodium malariae; Quinolines; Young Adult | 2021 |
Semimechanistic Pharmacokinetic and Pharmacodynamic Modeling of Piperaquine in a Volunteer Infection Study with Plasmodium falciparum Blood-Stage Malaria.
Topics: Antimalarials; Australia; Humans; Malaria; Malaria, Falciparum; New Zealand; Plasmodium falciparum; Quinolines; Volunteers | 2021 |
A tablet derived from
Topics: Andrographis paniculata; Animals; Artemisinins; Female; Malaria; Mice; Mice, Inbred BALB C; Piperazines; Placenta; Pregnancy; Quinolines; Tablets | 2021 |
Electrocardiographic effect of artemisinin-piperaquine, dihydroartemisinin-piperaquine, and artemether-lumefantrine treatment in falciparum malaria patients.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Electrocardiography; Humans; Malaria; Malaria, Falciparum; Quinolines | 2021 |
Structure-switching aptamer sensors for the specific detection of piperaquine and mefloquine.
Topics: Antimalarials; Aptamers, Nucleotide; Humans; Malaria; Mefloquine; Quinolines | 2021 |
Isolation of Mutants With Reduced Susceptibility to Piperaquine From a Mutator of the Rodent Malaria Parasite
Topics: Animals; Antimalarials; Malaria; Malaria, Falciparum; Mice; Parasites; Plasmodium berghei; Plasmodium falciparum; Protozoan Proteins; Quinolines; Rodentia | 2021 |
Efficacy of dihydroartemisinin/piperaquine in patients with non-complicated Plasmodium falciparum malaria in Yaoundé, Cameroon.
Topics: Antimalarials; Artemisinins; Cameroon; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Quinolines | 2021 |
Acute eosinophilic pneumonia following artenimol-piperaquine exposure.
Topics: Adult; Antimalarials; Artemisinins; Diagnosis, Differential; Humans; Malaria; Male; Pulmonary Eosinophilia; Quinolines; Tomography, X-Ray Computed; Travel | 2017 |
Intermittent preventive treatment for malaria among children in a refugee camp in Northern Uganda: lessons learned.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Cross-Sectional Studies; Drug Combinations; Female; Humans; Incidence; Infant; Malaria; Male; Parasitemia; Prevalence; Quinolines; Refugee Camps; Uganda | 2017 |
Ex vivo susceptibility and genotyping of Plasmodium falciparum isolates from Pikine, Senegal.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Fluorescent Dyes; Genotype; Genotyping Techniques; Humans; Indoles; Inhibitory Concentration 50; Malaria; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Pyrimethamine; Quinolines; Senegal; Young Adult | 2017 |
The application of physiologically based pharmacokinetic modelling to assess the impact of antiretroviral-mediated drug-drug interactions on piperaquine antimalarial therapy during pregnancy.
Topics: Alkynes; Antimalarials; Benzoxazines; Cyclopropanes; Drug Interactions; Female; HIV Protease Inhibitors; Humans; Malaria; Models, Biological; Population Groups; Pregnancy; Quinolines; Ritonavir; Serum Albumin, Human | 2017 |
Response to "Antiretroviral Therapy With Efavirenz in HIV-Infected Pregnant Women: Understanding the Possible Mechanisms for Drug-Drug Interaction".
Topics: Alkynes; Artemisinins; Benzoxazines; Chemoprevention; Cyclopropanes; Drug Interactions; Female; HIV; HIV Infections; Humans; Malaria; Pregnancy; Quinolines | 2018 |
Antiretroviral Therapy With Efavirenz in HIV-Infected Pregnant Women: Understanding the Possible Mechanisms for Drug-Drug Interaction.
Topics: Alkynes; Artemisinins; Benzoxazines; Chemoprevention; Cyclopropanes; Drug Interactions; Female; HIV; HIV Infections; Humans; Malaria; Pregnancy; Quinolines | 2018 |
Ivermectin: repurposing an old drug to complement malaria vector control.
Topics: Animals; Artemisinins; Double-Blind Method; Drug Repositioning; Ivermectin; Kenya; Malaria; Mosquito Vectors; Quinolines | 2018 |
Reappraising the cardiosafety of dihydroartemisinin-piperaquine.
Topics: Artemisinins; Bayes Theorem; Humans; Malaria; Quinolines | 2018 |
Efficacy of artemisinin-based combination therapies and prevalence of molecular markers associated with artemisinin, piperaquine and sulfadoxine-pyrimethamine resistance in Sierra Leone.
Topics: Antimalarials; Artemisinins; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Mutation; Quinolines; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2018 |
High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug.
Topics: Administration, Oral; Adult; Animals; Artemisinins; Double-Blind Method; Ivermectin; Kenya; Malaria; Parasitic Diseases; Quinolines; Scabies | 2018 |
Integrated point-of-care testing (POCT) of HIV, syphilis, malaria and anaemia in antenatal clinics in western Kenya: A longitudinal implementation study.
Topics: Adult; Anemia; Anti-Bacterial Agents; Anti-HIV Agents; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Dietary Supplements; Erythromycin; Female; Folic Acid; Guideline Adherence; Health Personnel; HIV Infections; Humans; Iron, Dietary; Kenya; Laboratory Proficiency Testing; Longitudinal Studies; Malaria; Penicillins; Point-of-Care Testing; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Complications, Infectious; Prenatal Care; Quinine; Quinolines; Syphilis; Trimethoprim, Sulfamethoxazole Drug Combination | 2018 |
[Diagnosis and Treatment of the First Imported Case of Plasmodium knowlesi Infection in China].
Topics: Animals; Antimalarials; Artemisinins; China; Chloroquine; Erythrocytes; Hemeproteins; Humans; Malaria; Microscopy; Plasmodium knowlesi; Polymerase Chain Reaction; Primaquine; Quinolines; Trophozoites | 2016 |
Electrocardiographic Safety of Repeated Monthly Dihydroartemisinin-Piperaquine as a Candidate for Mass Drug Administration.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Drug Administration Schedule; Drug Combinations; Electrocardiography; Female; Healthy Volunteers; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Mass Drug Administration; Middle Aged; Papua New Guinea; Patient Safety; Prospective Studies; Quinolines | 2018 |
Mass Drug Administration to Control and Eliminate Malaria in Africa: How Do We Best Utilize the Tools at Hand?
Topics: Africa; Artemisinins; Gambia; Humans; Malaria; Mass Drug Administration; Prospective Studies; Quinolines | 2019 |
Mass Drug Administration With Dihydroartemisinin-piperaquine and Malaria Transmission Dynamics in The Gambia: A Prospective Cohort Study.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Disease Transmission, Infectious; Female; Gambia; Health Services Research; Humans; Incidence; Infant; Malaria; Male; Mass Drug Administration; Middle Aged; Prevalence; Prospective Studies; Quinolines; Risk Assessment; Young Adult | 2019 |
Case Report: Birth Outcome and Neurodevelopment in Placental Malaria Discordant Twins.
Topics: Antimalarials; Artemisinins; Developmental Disabilities; Diseases in Twins; Female; Humans; Infant; Infant, Newborn; Malaria; Placenta; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Premature Birth; Quinolines | 2019 |
Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method.
Topics: Adolescent; Amodiaquine; Antimalarials; Arrhythmias, Cardiac; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Heart Rate; Humans; Long QT Syndrome; Malaria; Malaria, Falciparum; Male; Quinolines; Young Adult | 2019 |
Beyond birthweight: benefits and risks of preventing malaria in pregnancy.
Topics: Artemisinins; Double-Blind Method; Drug Combinations; Female; Humans; Malaria; Pregnancy; Pyrimethamine; Quinolines; Risk Assessment; Sulfadoxine | 2019 |
Clinical impact of the two ART resistance markers, K13 gene mutations and DPC3 in Vietnam.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Child; Child, Preschool; Drug Resistance; Female; Humans; Malaria; Male; Mutation; Plasmodium falciparum; Protozoan Proteins; Quinolines; Vietnam; Young Adult | 2019 |
[Descriptive study of malaria cases in the paediatric population in a reference hospital in Valencia, Spain, between 1993 and 2015].
Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Artesunate; Atovaquone; Child; Child, Preschool; Drug Combinations; Equatorial Guinea; Female; Hospitals, Community; Humans; Infant; Malaria; Male; Proguanil; Quinine; Quinolines; Retrospective Studies; Sex Distribution; Spain; Symptom Assessment | 2020 |
The unanticipated benefits of protecting young children from malaria.
Topics: Artemisinins; Child; Child, Preschool; Double-Blind Method; Humans; Malaria; Quinolines | 2019 |
Infectivity and Screening of Anti-piperaquine Genes in Mice Infected with Piperaquine-Sensitive and Piperaquine-Resistant Plasmodium berghei.
Topics: Animals; Antimalarials; Disease Models, Animal; Humans; Malaria; Male; Mice; Plasmodium berghei; Protozoan Proteins; Quinolines; Virulence | 2019 |
Devising a strategy for prevention of malaria in pregnant women in the Asia Pacific.
Topics: Artemisinins; Asia; Female; Humans; Indonesia; Malaria; Pregnancy; Quinolines | 2019 |
MMV in partnership: the Eurartesim® experience.
Topics: Adolescent; Adult; Artemisinins; Cambodia; Child; Child, Preschool; Drug Approval; Drug Combinations; Humans; Infant; Infant, Newborn; International Cooperation; Malaria; Public-Private Sector Partnerships; Quinolines | 2013 |
Population pharmacokinetics of mefloquine, piperaquine and artemether-lumefantrine in Cambodian and Tanzanian malaria patients.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Cambodia; Child; Child, Preschool; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria; Male; Mefloquine; Middle Aged; Plasma; Quinolines; Tanzania; Young Adult | 2013 |
Optimizing the programmatic deployment of the anti-malarials artemether-lumefantrine and dihydroartemisinin-piperaquine using pharmacological modelling.
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Computer Simulation; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria; Male; Quinolines; Treatment Outcome; Young Adult | 2014 |
Dihydroartemisinin-piperaquine vs. artemether-lumefantrine for first-line treatment of uncomplicated malaria in African children: a cost-effectiveness analysis.
Topics: Africa; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Cost-Benefit Analysis; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Infant; Infant, Newborn; Malaria; Markov Chains; Outcome Assessment, Health Care; Quinolines | 2014 |
Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model.
Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Combinations; Malaria; Mice; Parasite Load; Parasitic Sensitivity Tests; Plasmodium berghei; Quinolines; Recurrence | 2014 |
Protection against malaria by immunization with non-attenuated sporozoites under single-dose piperaquine-tetraphosphate chemoprophylaxis.
Topics: Animals; CD8-Positive T-Lymphocytes; Chemoprevention; Chloroquine; Disease Models, Animal; Female; Immunologic Memory; Liver; Malaria; Malaria Vaccines; Mice, Inbred C57BL; Plasmodium berghei; Quinolines; Spleen; Sporozoites | 2014 |
Cost-effectiveness of dihydroartemisinin-piperaquine compared with artemether-lumefantrine for treating uncomplicated malaria in children at a district hospital in Tanzania.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Cost-Benefit Analysis; Drug Combinations; Ethanolamines; Female; Fluorenes; Health Care Costs; Hospitals, District; Humans; Infant; Infant, Newborn; Malaria; Male; Models, Statistical; Quinolines; Tanzania; Treatment Outcome | 2014 |
Fitness cost of resistance for lumefantrine and piperaquine-resistant Plasmodium berghei in a mouse model.
Topics: Animals; Antimalarials; Disease Models, Animal; Drug Resistance; Ethanolamines; Fluorenes; Genetic Fitness; Lumefantrine; Malaria; Male; Mice; Plasmodium berghei; Quinolines | 2015 |
Population Pharmacokinetics of Piperaquine in Young Ugandan Children Treated With Dihydroartemisinin-Piperaquine for Uncomplicated Malaria.
Topics: Antimalarials; Artemisinins; Child, Preschool; Drug Therapy, Combination; Humans; Infant; Malaria; Prospective Studies; Quinolines; Uganda | 2015 |
Prospective observational study to evaluate the clinical safety of the fixed-dose artemisinin-based combination Eurartesim® (dihydroartemisinin/piperaquine), in public health facilities in Burkina Faso, Mozambique, Ghana, and Tanzania.
Topics: Adolescent; Adult; Africa; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Cohort Studies; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Health Facilities; Heart Conduction System; Humans; Infant; Infant, Newborn; Longitudinal Studies; Malaria; Male; Middle Aged; Prospective Studies; Quinolines; Young Adult | 2015 |
Treatment policy change to dihydroartemisinin-piperaquine contributes to the reduction of adverse maternal and pregnancy outcomes.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Female; Humans; Indonesia; Infant, Newborn; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Quinolines; Young Adult | 2015 |
Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt.
Topics: Alleles; Chloroquine; Drug Resistance; Evolution, Molecular; French Guiana; Genetic Markers; Genome; Genotype; Haplotypes; Humans; Inhibitory Concentration 50; Malaria; Membrane Transport Proteins; Mutation; Phenotype; Plasmodium falciparum; Prevalence; Principal Component Analysis; Protozoan Proteins; Quinolines; Retrospective Studies | 2015 |
Budget Impact Analysis of Using Dihydroartemisinin-Piperaquine to Treat Uncomplicated Malaria in Children in Tanzania.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Cost-Benefit Analysis; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Care Costs; Humans; Infant; Malaria; Markov Chains; Models, Economic; Quinolines; Tanzania | 2016 |
Treatment outcomes in a safety observational study of dihydroartemisinin/piperaquine (Eurartesim(®)) in the treatment of uncomplicated malaria at public health facilities in four African countries.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Burkina Faso; Child; Child, Preschool; Female; Ghana; Health Facilities; Humans; Infant; Longitudinal Studies; Malaria; Male; Middle Aged; Mozambique; Quinolines; Tanzania; Treatment Outcome; Young Adult | 2016 |
Factors Associated with Non-Participation and Non-Adherence in Directly Observed Mass Drug Administration for Malaria in The Gambia.
Topics: Adolescent; Adult; Aged; Anthropology; Antimalarials; Artemisinins; Attitude to Health; Child; Child, Preschool; Decision Making; Drug Administration Schedule; Female; Follow-Up Studies; Gambia; Humans; Infant; Infant, Newborn; Malaria; Male; Medication Adherence; Middle Aged; Patient Compliance; Patient Education as Topic; Quinolines; Rural Health Services; Rural Population; Young Adult | 2016 |
Back on TRAC: New trial launched in bid to outpace multidrug-resistant malaria.
Topics: Antimalarials; Artemisinins; Asia, Southeastern; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; India; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinolines | 2016 |
Rethinking Dosing Regimen Selection of Piperaquine for Malaria Chemoprevention: A Simulation Study.
Topics: Antimalarials; Chemoprevention; Computer Simulation; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Models, Theoretical; Quinolines | 2016 |
The acceptability of mass administrations of anti-malarial drugs as part of targeted malaria elimination in villages along the Thai-Myanmar border.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Disease Eradication; Disease Transmission, Infectious; Female; Humans; Infant; Malaria; Male; Middle Aged; Myanmar; Patient Acceptance of Health Care; Pregnancy; Primaquine; Quinolines; Surveys and Questionnaires; Thailand; Young Adult | 2016 |
Multi-Country Evaluation of Safety of Dihydroartemisinin/Piperaquine Post-Licensure in African Public Hospitals with Electrocardiograms.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Black People; Blood Cell Count; Blood Chemical Analysis; Burkina Faso; Child; Child, Preschool; Data Interpretation, Statistical; Electrocardiography; Female; Ghana; Heart; Hospitals, Public; Humans; Malaria; Male; Mozambique; Quinolines; Tanzania; Ventricular Dysfunction; Young Adult | 2016 |
Impact of Extended Duration of Artesunate Treatment on Parasitological Outcome in a Cytocidal Murine Malaria Model.
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Disease Models, Animal; Female; Malaria; Mice; Mice, Inbred BALB C; Quinolines | 2017 |
Antimalarial therapies in children from Papua New Guinea.
Topics: Antimalarials; Artemether; Artemisinins; Biological Availability; Drug Therapy, Combination; Ethanolamines; Fats; Fluorenes; Humans; Lumefantrine; Malaria; Quinolines; Treatment Failure | 2009 |
Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Drug Resistance; Ethanolamines; Female; Fluorenes; Lumefantrine; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Quinolines; Serial Passage | 2009 |
Piperaquine pharmacodynamics and parasite viability in a murine malaria model.
Topics: Animals; Antimalarials; Disease Models, Animal; Malaria; Male; Mice; Mice, Inbred BALB C; Plasmodium berghei; Quinolines | 2009 |
Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue.
Topics: Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Blotting, Southern; Dose-Response Relationship, Drug; Ethanolamines; Fluorenes; Genetic Vectors; Germ Cells, Plant; Green Fluorescent Proteins; Luciferases; Lumefantrine; Malaria; Methylene Blue; Naphthyridines; Plasmodium falciparum; Quinolines; Sexual Development | 2011 |
Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated malaria.
Topics: Adolescent; Adult; Antimalarials; Area Under Curve; Artemisinins; Body Weight; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Malaria; Middle Aged; Myanmar; Nonlinear Dynamics; Population; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Parasitic; Quinolines; Software; Tandem Mass Spectrometry; Thailand; Young Adult | 2012 |
Assessing the consistency assumption by exploring treatment by covariate interactions in mixed treatment comparison meta-analysis: individual patient-level covariates versus aggregate trial-level covariates.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Dapsone; Drug Combinations; Ethanolamines; Fluorenes; Humans; Malaria; Meta-Analysis as Topic; Models, Statistical; Outcome Assessment, Health Care; Proguanil; Quinolines; Regression Analysis | 2012 |
[Immunological analysis of piperaquine-resistant murine model of Plasmodium berghei ANKA strain].
Topics: Animals; Cells, Cultured; Disease Models, Animal; Drug Resistance; Interferon-gamma; Lymphocytes; Malaria; Male; Mice; Mice, Inbred Strains; Nitric Oxide; Plasmodium berghei; Quinolines; Spleen | 2012 |
Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania.
Topics: Alleles; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Arylamine N-Acetyltransferase; Base Sequence; Cambodia; Cytochrome P-450 Enzyme System; Drug Combinations; Ethanolamines; Fluorenes; Gene Frequency; Humans; Isoenzymes; Malaria; Mefloquine; Pharmacogenetics; Polymorphism, Single Nucleotide; Quinolines; Sequence Analysis, DNA; Tanzania | 2013 |
In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Erythrocytes; Female; Heterocyclic Compounds, 1-Ring; Humans; Malaria; Mice; Parasitemia; Parasitic Sensitivity Tests; Peroxides; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinolines; Spiro Compounds | 2007 |
[4-Aminoquinoline-sensitivity of Plasmodium falciparum in Madagascar. I. Study in two regions of the west coast].
Topics: Adolescent; Aged; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Drug Resistance, Microbial; Humans; Madagascar; Malaria; Piperazines; Plasmodium falciparum; Quinolines | 1984 |
[4-Aminoquinoline-sensitivity of Plasmodium falciparum in Madagascar. II. Study in two regions of the east coast].
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Child; Chloroquine; Drug Resistance, Microbial; Humans; Madagascar; Malaria; Piperazines; Plasmodium falciparum; Quinolines | 1984 |
[4-Aminoquinoline-sensitivity of Plasmodium falciparum in Madagascar. III. Studies in three regions of the interior].
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Madagascar; Malaria; Piperazines; Plasmodium falciparum; Quinolines | 1984 |
[Studies on piperaquine as long-acting antimalarial drug against Plasmodium berghei in mice].
Topics: Animals; Antimalarials; Chloroquine; Delayed-Action Preparations; Female; Malaria; Mice; Plasmodium berghei; Quinolines | 1982 |
[The antimalarial effects of piperaquine phosphate and sulphadoxine composite as tested in Hainan Island (author's transl)].
Topics: Antimalarials; Drug Combinations; Humans; Malaria; Quinolines; Sulfadoxine; Sulfanilamides | 1981 |
Field observations on the antimalarial piperaquine.
Topics: Adolescent; Adult; Antimalarials; Child; China; Humans; Malaria; Quinolines | 1982 |
[Studies on residual antimalarial activity of tripynadine in mice and monkeys].
Topics: Animals; Antimalarials; Macaca mulatta; Malaria; Mice; Naphthyridines; Plasmodium berghei; Plasmodium cynomolgi; Quinolines | 1993 |
Histopathological changes of Macaca mulatta infected with Plasmodium knowlesi.
Topics: Animals; Artemisinins; Artesunate; Macaca mulatta; Malaria; Monkey Diseases; Plasmodium knowlesi; Quinolines; Sesquiterpenes; Suppositories | 2001 |
Recent studies on antimalarial efficacy of piperaquine and hydroxypiperaquine.
Topics: Animals; Antimalarials; Drug Resistance; Humans; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Quinolines | 1991 |
[In vivo sensitivity of Plasmodium falciparum to piperaquine phosphate assayed in Linshui and Baisha counties, Hainan Province].
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; China; Drug Resistance; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinolines | 1989 |
[Suppressive effect of 3 combinations of antimalarials against Plasmodium cynomolgi].
Topics: Animals; Antimalarials; Drug Therapy, Combination; Macaca mulatta; Malaria; Naphthyridines; Quinazolines; Quinolines | 1987 |
Plasmodium falciparum in Madagascar: in vivo and in vitro sensitivity to seven drugs.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Humans; Infant; Madagascar; Malaria; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines | 1985 |
[In vivo and in vitro sensitivity to 4-aminoquinolines of Plasmodium falciparum in Madagascar: results of 2 years' study].
Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Madagascar; Malaria; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines | 1985 |
[Development of a piperaquine-resistant line of Plasmodium berghei K 173 strain].
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes | 1985 |
[Sensitivity of Plasmodium falciparum to piperaquine in Baoting County, Hainan Island].
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; China; Drug Synergism; Gametogenesis; Humans; Malaria; Middle Aged; Plasmodium falciparum; Primaquine; Quinolines | 1985 |
[Resistance to piperaquine phosphate in Hainan islanders with pernicious malaria].
Topics: Adolescent; Adult; Animals; Antimalarials; Child; China; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Quinolines | 1985 |