picrotoxin has been researched along with Pain in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (27.27) | 18.7374 |
| 1990's | 9 (40.91) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alhumayyd, MS; Bukhari, IA; Gilani, AH; Mahesar, AL; Pivac, N | 1 |
| Hu, XD; Liu, YN; Ma, ZA; Suo, ZW; Yang, X; Zhang, ZY | 1 |
| Ojewole, JA | 1 |
| Cervero, F; Garcia-Nicas, E; Laird, JM | 1 |
| Castro, M; Duarte, I; Francischi, J; Pacheco, D; Perez, A; Reis, G | 1 |
| Cromer, BA; Harvey, RJ; Lynch, JW; Parker, MW; Yang, Z | 1 |
| Nishikawa, N; Yokota, T | 1 |
| Berkley, KJ; Hubscher, CH | 1 |
| Montagne-Clavel, J; Olivéras, JL | 3 |
| Olausson, B; Shyu, BC; Xu, ZQ | 1 |
| Crosby, G; Goto, T; Marota, JJ | 1 |
| Ghazi-khansari, M; Hashemi, B; Heidari, MR; Khalili, F; Zarrindast, MR | 1 |
| Matsumoto, K; Nguyen, TT; Watanabe, H | 1 |
| Hanai, F; Koyama, N; Yokota, T | 1 |
| Nemmani, KV; Ramarao, P | 1 |
| Bossut, D; Frenk, H; Mayer, DJ | 1 |
| Bossut, D; Frenk, H; Mayer, DJ; Urca, G | 1 |
| Aley, KO; Kulkarni, SK | 1 |
| Beyer, C; Komisaruk, BR; Roberts, LA | 1 |
| Fields, HL; Moreau, JL | 1 |
22 other study(ies) available for picrotoxin and Pain
| Article | Year |
|---|---|
The analgesic and anticonvulsant effects of piperine in mice.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Anticonvulsants; Benzodioxoles; Hot Temperature; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pentylenetetrazole; Picrotoxin; Piper nigrum; Piperidines; Polyunsaturated Alkamides; Seizures | 2013 |
Spinophilin-Targeted Protein Phosphatase-1 Alleviated Inflammatory Pain by Negative Control of MEK/ERK Signaling in Spinal Cord Dorsal Horn of Rats.
Topics: Animals; Central Nervous System Stimulants; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Freund's Adjuvant; HEK293 Cells; Humans; In Vitro Techniques; Inflammation; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Microfilament Proteins; Nerve Tissue Proteins; Pain; Pain Measurement; Patch-Clamp Techniques; Picrotoxin; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord Dorsal Horn | 2015 |
Analgesic and anticonvulsant properties of Tetrapleura tetraptera (Taub) (Fabaceae) fruit aqueous extract in mice.
Topics: Acetic Acid; Analgesics; Animals; Anticonvulsants; Bicuculline; Female; Fruit; Hot Temperature; Male; Mice; Mice, Inbred BALB C; Pain; Pentylenetetrazole; Phytotherapy; Picrotoxin; Plant Extracts; Seizures; Tetrapleura | 2005 |
GABAA-Receptor blockade reverses the injury-induced sensitization of nociceptor-specific (NS) neurons in the spinal dorsal horn of the rat.
Topics: Action Potentials; Animals; Bicuculline; Capsaicin; Electrophysiology; Female; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mustard Plant; Neurons; Nociceptors; Pain; Physical Stimulation; Picrotoxin; Plant Oils; Posterior Horn Cells; Rats; Rats, Wistar; Stimulation, Chemical | 2006 |
Involvement of GABA A receptor-associated chloride channels in the peripheral antinociceptive effect induced by GABA A receptor agonist muscimol.
Topics: Analysis of Variance; Animals; Bicuculline; Chloride Channels; Dinoprostone; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Injections, Subcutaneous; Male; Muscimol; Pain; Pain Measurement; Picrotoxin; Potassium Channel Blockers; Potassium Channels; Pressure; Rats; Rats, Wistar; Receptors, GABA-A | 2007 |
A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore.
Topics: Data Interpretation, Statistical; DNA, Complementary; Electrophysiology; Glycine; Humans; Hydrogen Bonding; Models, Molecular; Mutagenesis; Neurons, Afferent; Pain; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Receptors, Glycine; Sesterterpenes; Synapses | 2007 |
Effects of picrotoxin upon response characteristics of wide dynamic range neurons in the spinal cord of cat and monkey.
Topics: Analgesics; Animals; Cats; Hot Temperature; Macaca; Pain; Physical Stimulation; Picrotoxin; Sensory Thresholds; Species Specificity; Spinal Cord; Touch | 1982 |
Are there separate central nervous system pathways for touch and pain?
Topics: Animals; Female; Injections, Intravenous; Medulla Oblongata; Models, Neurological; Neurons; Nociceptors; Pain; Pelvis; Perception; Physical Stimulation; Picrotoxin; Rats; Skin; Skin Physiological Phenomena; Spinal Cord; Touch; Viscera | 1995 |
The GABAA receptor antagonist picrotoxin induces a 'pain-like' behavior when administered into the thalamic reticular nucleus of the behaving rat: a possible model for 'central' pain?
Topics: Animals; Behavior, Animal; Disease Models, Animal; GABA-A Receptor Antagonists; Male; Microinjections; Pain; Picrotoxin; Rats; Rats, Sprague-Dawley; Thalamic Nuclei | 1994 |
Dorsal column inhibition of nociceptive thalamic cells mediated by gamma-aminobutyric acid mechanisms in the cat.
Topics: Afferent Pathways; Animals; Baclofen; Cats; Dental Pulp; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Homocysteine; Pain; Picrotoxin; Spinal Cord; Thalamus | 1994 |
Pentobarbitone, but not propofol, produces pre-emptive analgesia in the rat formalin model.
Topics: Analgesics; Anesthesia, Intravenous; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Male; Pain; Pentobarbital; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Effect of picrotoxin on antinociception in the formalin test.
Topics: Animals; Formaldehyde; GABA Antagonists; Male; Mice; Pain; Pain Measurement; Pain Threshold; Picrotoxin | 1996 |
Picrotoxin produces a "central" pain-like syndrome when microinjected into the somato-motor cortex of the rat.
Topics: Animals; Behavior, Animal; Male; Microinjections; Pain; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures; Somatosensory Cortex | 1996 |
Involvement of supraspinal GABA-ergic systems in clonidine-induced antinociception in the tail-pinch test in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Bicuculline; Clonidine; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pain; Picrotoxin; Receptors, GABA; Tail | 1997 |
Cholinergic modulation of the picrotoxin-induced electrocorticographical events and behavioral "pain-like" symptoms at somatomotor cortical level in the rat.
Topics: Animals; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Electroencephalography; GABA Antagonists; Male; Microinjections; Motor Cortex; Muscarinic Antagonists; Pain; Physostigmine; Picrotoxin; Rats; Rats, Sprague-Dawley; Somatosensory Cortex | 1997 |
Does intravenous administration of GABA(A) receptor antagonists induce both descending antinociception and touch-evoked allodynia?
Topics: Analgesics; Anesthetics, Local; Animals; Brain Mapping; Cats; Decerebrate State; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; Hot Temperature; Lidocaine; Microinjections; Neurons; Pain; Periaqueductal Gray; Physical Stimulation; Picrotoxin; Raphe Nuclei; Spinal Cord; Touch | 1998 |
Role of benzodiazepine-GABAA receptor complex in attenuation of U-50,488H-induced analgesia and inhibition of tolerance to its analgesia by ginseng total saponin in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Drug Antagonism; Drug Tolerance; Drugs, Chinese Herbal; Flumazenil; Ginsenosides; Injections, Intraperitoneal; Male; Mice; Pain; Pain Threshold; Panax; Picrotoxin; Receptors, GABA-A; Receptors, Opioid, kappa; Saponins; Tail | 2002 |
Is substance P a primary afferent neurotransmitter for nociceptive input? II. Spinalization does not reduce and intrathecal morphine potentiates behavioral responses to substance P.
Topics: Animals; Decerebrate State; Drug Interactions; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P | 1988 |
Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds.
Topics: Afferent Pathways; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P | 1988 |
GABAergic agents-induced antinociceptive effect in mice.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Mice; Morphine; Muscimol; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds; Valproic Acid | 1989 |
Nociceptive responses to altered GABAergic activity at the spinal cord.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Injections, Spinal; Motor Activity; Muscimol; Pain; Pain Measurement; Physical Stimulation; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds; Tail; Vocalization, Animal | 1986 |
Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission.
Topics: Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Morphine; Muscimol; Neural Pathways; Pain; Pain Measurement; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |