phillygenin has been researched along with Pain* in 1 studies
1 other study(ies) available for phillygenin and Pain
Article | Year |
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Phillygenin from Forsythia suspensa leaves exhibits analgesic potential and anti-inflammatory activity in carrageenan-induced paw edema in mice.
Forsythia suspensa (Thunb.) Vahl (Oleaceae) leaves are valuable sources of phillygenin. This study aimed to isolate phillygenin from F. suspensa leaves and examine its analgesic and anti-inflammatory effects. Phillygenin was successfully extracted and isolated from F. suspensa leaves after fermentation. Phillygenin significantly reduced the number of writhing induced by acetic acid, prolonged the latency period in the hot plate test, and inhibited the xylene-induced ear edema and carrageenan-induced paw edema in mice. IL-6, TNF-α, IL-1β, NO, and PGE Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Forsythia; Inflammation; Mice; Pain; Plant Extracts | 2022 |