phenytoin has been researched along with Malaria in 4 studies
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") seizure prophylactic dose of fosphenytoin (18 mg kg-1 phenytoin sodium equivalents) were concomitantly administered to 15 African children with malaria." | 5.10 | Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration. ( Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR; Otieno, GO, 2002) |
| " None of the dosing regimens caused toxicological manifestations other than hepatomegaly." | 1.27 | Alteration of bone marrow cell cycle kinetics by diphenylhydantoin: relationship to folate utilization and immune function. ( Boorman, GA; Hong, L; Luster, MI; Pung, O; Tucker, AN, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ogutu, BR | 1 |
| Newton, CR | 2 |
| Muchohi, SN | 1 |
| Otieno, GO | 1 |
| Kokwaro, GO | 1 |
| Sadarangani, M | 1 |
| Seaton, C | 1 |
| Scott, JA | 1 |
| Ogutu, B | 1 |
| Edwards, T | 1 |
| Prins, A | 1 |
| Gatakaa, H | 1 |
| Idro, R | 1 |
| Berkley, JA | 1 |
| Peshu, N | 1 |
| Neville, BG | 1 |
| Tucker, AN | 1 |
| Hong, L | 1 |
| Boorman, GA | 1 |
| Pung, O | 1 |
| Luster, MI | 1 |
| Heischkeil, R | 1 |
1 trial available for phenytoin and Malaria
| Article | Year |
|---|---|
Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration.
Topics: Anti-Bacterial Agents; Anticonvulsants; Area Under Curve; Cefotaxime; Child, Preschool; Chlorampheni | 2002 |
3 other studies available for phenytoin and Malaria
| Article | Year |
|---|---|
Incidence and outcome of convulsive status epilepticus in Kenyan children: a cohort study.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Child; Child, Preschool; Cohort Studies; Data Int | 2008 |
Alteration of bone marrow cell cycle kinetics by diphenylhydantoin: relationship to folate utilization and immune function.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Cycle; Female; Folic Acid; Hematopoietic Stem Cells; I | 1985 |
[Antimetabolites of folic acid metabolism with chemotherapeutic activity against rodent malaria (Plasmodium vinckei)].
Topics: Aminopterin; Animals; Cycloheximide; Female; Folic Acid; Folic Acid Antagonists; Hydantoins; Malaria | 1973 |