phenylbutazone has been researched along with Ulcer in 38 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
Excerpt | Relevance | Reference |
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"A 15-year-old Quarter Horse gelding and a 26-year-old Thoroughbred gelding were evaluated because of hematuria of 4 to 6 days' duration following prolonged oral administration of phenylbutazone." | 7.77 | Ulcerative cystitis associated with phenylbutazone administration in two horses. ( Aleman, M; Higgins, JK; Nieto, JE, 2011) |
"Influence of dietary protein deficiency on the anti-inflammatory and ulcerogenic effects and on the kinetics of phenylbutazone was studied in male Sprague-Dawley rats fed ad libitum a 21% (control) or a 5% (low) protein diet for 3 weeks." | 7.66 | Influence of dietary protein on the anti-inflammatory and ulcerogenic effects and on the pharmacokinetics of phenylbutazone in rats. ( Varma, DR, 1979) |
"A 15-year-old Quarter Horse gelding and a 26-year-old Thoroughbred gelding were evaluated because of hematuria of 4 to 6 days' duration following prolonged oral administration of phenylbutazone." | 3.77 | Ulcerative cystitis associated with phenylbutazone administration in two horses. ( Aleman, M; Higgins, JK; Nieto, JE, 2011) |
" Anti-inflammatory and ulcerogenic activities in vivo were evaluated and compared with the standard drugs, phenylbutazone and indomethacin." | 3.71 | Synthesis and anti-inflammatory activity of 1-acetyl-5-substituted aryl-3-(beta-aminonaphthyl)-2-pyrazolines and beta-(substituted aminoethyl) amidonaphthalenes. ( Bansal, E; Kumar, A; Srivastava, VK, 2001) |
"Influence of dietary protein deficiency on the anti-inflammatory and ulcerogenic effects and on the kinetics of phenylbutazone was studied in male Sprague-Dawley rats fed ad libitum a 21% (control) or a 5% (low) protein diet for 3 weeks." | 3.66 | Influence of dietary protein on the anti-inflammatory and ulcerogenic effects and on the pharmacokinetics of phenylbutazone in rats. ( Varma, DR, 1979) |
" A decrease in total blood neutrophil count occurred in all horses, and was associated with toxic left shift in horses given the 2 larger dosage schedules." | 1.27 | Effects of large doses of phenylbutazone administration to horses. ( French, TW; MacKay, RJ; Mayhew, IG; Nguyen, HT, 1983) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (84.21) | 18.7374 |
1990's | 1 (2.63) | 18.2507 |
2000's | 4 (10.53) | 29.6817 |
2010's | 1 (2.63) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Auzzi, G | 1 |
Bruni, F | 1 |
Cecchi, L | 1 |
Costanzo, A | 1 |
Vettori, LP | 1 |
Pirisino, R | 1 |
Corrias, M | 1 |
Ignesti, G | 1 |
Banchelli, G | 1 |
Raimondi, L | 1 |
Khanum, SA | 3 |
D, VT | 1 |
Shashikanth, S | 2 |
Firdouse, A | 2 |
Venu, TD | 1 |
Manuprasad, BK | 1 |
Mohamed, R | 1 |
Vishwanth, BS | 1 |
Khanum, NF | 1 |
Shashikanth, M | 1 |
Aleman, M | 1 |
Nieto, JE | 1 |
Higgins, JK | 1 |
CHARET, R | 1 |
SIEGEL, I | 1 |
GOSPODINOFF, A | 2 |
RAYMOND, LF | 2 |
LEVRAT, M | 1 |
LAMBERT, R | 1 |
VARRO, V | 4 |
CSERNAY, L | 4 |
JAVOR, T | 2 |
GRUBER, K | 1 |
VILARDELL, F | 1 |
TACHDJIAN, V | 1 |
CAHEN, R | 1 |
PESSONNIER, A | 1 |
JUNG, I | 3 |
FINKBINER, RB | 1 |
RICHARDSON, FM | 1 |
VILARBONET, J | 1 |
SANYAL, AK | 1 |
GUPTA, KK | 1 |
CHOWDHURY, NK | 1 |
GIETKA, J | 2 |
WISSMER, BA | 1 |
ADAMI, E | 1 |
SMEJKAL, V | 1 |
DLABAC, A | 1 |
TRCKA, V | 1 |
Mackie, BS | 1 |
Traub, JL | 1 |
Gallina, AM | 1 |
Grant, BD | 1 |
Reed, SM | 1 |
Gavin, PR | 1 |
Paulsen, LM | 1 |
MacAllister, CG | 1 |
Neoptolemos, JP | 1 |
Locke, TJ | 1 |
MacKay, RJ | 1 |
French, TW | 1 |
Nguyen, HT | 1 |
Mayhew, IG | 1 |
Miller, RM | 1 |
Dresher, LK | 1 |
Snow, DH | 1 |
Douglas, TA | 1 |
Thompson, H | 1 |
Parkins, JJ | 1 |
Holmes, PH | 1 |
Hough, ME | 1 |
Steel, CM | 1 |
Bolton, JR | 1 |
Yovich, JV | 1 |
Bansal, E | 1 |
Srivastava, VK | 1 |
Kumar, A | 1 |
Varma, DR | 1 |
Lewis, DA | 1 |
Capstick, RB | 1 |
Ancill, RJ | 1 |
Bowers, J | 1 |
Arnold, IL | 1 |
Lowrie, HS | 2 |
38 other studies available for phenylbutazone and Ulcer
Article | Year |
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2-Phenylpyrazolo[1,5-a]pyrimidin-7-ones. A new class of nonsteroidal antiinflammatory drugs devoid of ulcerogenic activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Indomethacin; Male; Phenylbutazone; Pyrazoles; Pyr | 1983 |
Synthesis of some newer analogues of substituted dibenzoyl phenol as potent anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Cyclooxygenase Inhibitors; In Vitro Tec | 2004 |
Synthesis and anti-inflammatory activity of 2-(2-aroylaroxy)-4,6-dimethoxy pyrimidines.
Topics: Algorithms; Animals; Animals, Inbred Strains; Anti-Inflammatory Agents, Non-Steroidal; Disease Model | 2008 |
Synthesis and anti-inflammatory activity of 2-aryloxy methyl oxazolines.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Chemistry, Pharmaceutical; Drug Design; Edema; Ethan | 2008 |
Ulcerative cystitis associated with phenylbutazone administration in two horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cystitis; Hematuria; Horse Dise | 2011 |
Unusual reaction following use of phenylbutazone (butazolidin).
Topics: Adrenocorticotropic Hormone; Analgesics; Chlortetracycline; Drug Eruptions; Oral Ulcer; Phenylbutazo | 1953 |
[The ulcer-producing action of phenylbutazone].
Topics: Analgesics; Peptic Ulcer; Phenylbutazone; Ulcer | 1955 |
[Further comments on the ulcer-producing action of phenylbutazone].
Topics: Analgesics; Peptic Ulcer; Phenylbutazone; Ulcer | 1955 |
Neovascularization of the cornea due to butazolidin toxicity.
Topics: Cornea; Corneal Ulcer; Humans; Neovascularization, Pathologic; Phenylbutazone; Ulcer | 1957 |
Neovascularization of the cornea due to butazolidin toxicity.
Topics: Cornea; Corneal Ulcer; Humans; Neovascularization, Pathologic; Phenylbutazone; Ulcer | 1957 |
Neovascularization of the cornea due to butazolidin toxicity.
Topics: Cornea; Corneal Ulcer; Humans; Neovascularization, Pathologic; Phenylbutazone; Ulcer | 1957 |
Neovascularization of the cornea due to butazolidin toxicity.
Topics: Cornea; Corneal Ulcer; Humans; Neovascularization, Pathologic; Phenylbutazone; Ulcer | 1957 |
[Medically-induced ulcers in rat. I. Phenylbutazone].
Topics: Animals; Peptic Ulcer; Phenylbutazone; Rats; Ulcer | 1959 |
Experimental phenylbutzone ulcer in dogs.
Topics: Animals; Dogs; Peptic Ulcer; Phenylbutazone; Ulcer | 1959 |
[Ulcer perforations during antirheumatic therapy].
Topics: Antirheumatic Agents; Humans; Peptic Ulcer Perforation; Phenylbutazone; Salicylic Acid; Ulcer | 1962 |
[Ulcer hemorrhages caused by phenylbutazone in aged patients. (Study of 9 cases)].
Topics: Humans; Peptic Ulcer Hemorrhage; Phenylbutazone; Ulcer | 1961 |
[Pharmacological study of dihydroxyaluminum allantoinate and chlorhydroxyaluminum allantoinate. IV. Effect on experimental drug-induced ulcer].
Topics: Allantoin; Aluminum Hydroxide; Antacids; Drugs, Investigational; Phenylbutazone; Reserpine; Stomach | 1963 |
[The role of acid secretion in the pathogenesis of experimental phenylbutazone ulcer].
Topics: Atropine; Histamine; Humans; Peptic Ulcer; Phenylbutazone; Ulcer; Vagotomy | 1962 |
[The role of water retention in the pathogenesis of experimental phenylbutazone ulcer].
Topics: Acetazolamide; Chlorothiazide; Diuretics; Edema; Heart Failure; Organomercury Compounds; Peptic Ulce | 1963 |
[THE SIGNIFICANCE OF PITUITARY-ADRENAL AXIS IN THE PATHOGENESIS OF EXPERIMENTAL PHENYLBUTAZONE ULCER].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Cortisone; Desoxycorticosterone; Dogs; Phenylbutazone; | 1963 |
THE RESISTANT ULCER.
Topics: Alcoholic Beverages; Antacids; Diet; Diet Therapy; Gastrectomy; Glycopyrrolate; Humans; Parasympatho | 1963 |
[DRUG-INDUCED ULCER (CORTICOSTEROIDS: PHENYLBUTAZONE)].
Topics: Adrenal Cortex Hormones; Duodenal Ulcer; Endopeptidases; Gastric Juice; Humans; Pathology; Peptic Ul | 1963 |
STUDIES ON PEPTIC ULCERATION. I. ROLE OF BANANA IN PHENYLBUTAZONE INDUCED ULCERS.
Topics: Diet; Flavoring Agents; Fruit; Guinea Pigs; Musa; Pathology; Peptic Ulcer; Phenylbutazone; Research; | 1964 |
[EFFECT OF BUTAZOLIDIN ON THE GASTRIC MUCOSA (ATTEMPTED CLASSIFICATION OF THE MECHANISM OF ULCER FOLLOWING BUTAZOLIDIN THERAPY)].
Topics: Gastric Mucosa; Humans; Peptic Ulcer; Pharmacology; Phenylbutazone; Rats; Research; Toxicology; Ulce | 1964 |
[EFFECT OF BUTAZOLIDIN ON THE GASTRIC MUSA (ATTEMPTED CLARIFICATION OF THE MECHANISM OF ULCER FOLLOWING THE ADMINISTRATION OF BUTAZOLIDIN. II. BEHAVIOR OF MUCOPOLYSACCHARIDES IN THE GASTRIC MUCOSA].
Topics: Carbohydrate Metabolism; Gastric Mucosa; Glycosaminoglycans; Humans; Musa; Peptic Ulcer; Pharmacolog | 1964 |
A NEW WAY IN ULCER THERAPY?
Topics: Drug Therapy; Histamine; Peptic Ulcer; Pharmacology; Phenylbutazone; Prednisolone; Rats; Research; R | 1965 |
THE INFLUENCE OF A NEW RESERPINE DERIVATIVE, METHOXYPHENOSERPINE, ON EXPERIMENTAL ULCERS AND GASTRIC SECRETION IN RATS.
Topics: Cathartics; Gastric Juice; Pepsin A; Peptic Ulcer; Pharmacology; Phenylbutazone; Pylorus; Rats; Rese | 1964 |
Drug-induced ulcer of the lip.
Topics: Administration, Topical; Aged; Anti-Inflammatory Agents; Carcinoma, Squamous Cell; Chlorpromazine; D | 1967 |
Phenylbutazone toxicosis in the foal.
Topics: Animals; Barium Sulfate; Colonic Diseases; Diarrhea; Female; Gastric Mucosa; Gastroscopy; Horse Dise | 1983 |
Effects of toxic doses of phenylbutazone in ponies.
Topics: Administration, Oral; Animals; Gastrointestinal Diseases; Horse Diseases; Horses; Injections, Intrav | 1983 |
Recurrent small bowel obstruction associated with phenylbutazone.
Topics: Aged; Female; Humans; Ileal Diseases; Intestinal Obstruction; Phenylbutazone; Ulcer | 1983 |
Effects of large doses of phenylbutazone administration to horses.
Topics: Animals; Anti-Inflammatory Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Gastric Mucosa; G | 1983 |
Equine ulcerative lymphangitis caused by Pasteurella hemolytica (2 case reports).
Topics: Animals; Chloramphenicol; Furosemide; Horse Diseases; Horses; Lymphangitis; Male; Pasteurella Infect | 1981 |
Phenylbutazone toxicity in ponies.
Topics: Animals; Gastrointestinal Diseases; Horse Diseases; Horses; Hypoproteinemia; Phenylbutazone; Protein | 1980 |
Ulceration and stricture of the right dorsal colon after phenylbutazone administration in four horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Constriction, Pathologic; Fatal | 1999 |
Synthesis and anti-inflammatory activity of 1-acetyl-5-substituted aryl-3-(beta-aminonaphthyl)-2-pyrazolines and beta-(substituted aminoethyl) amidonaphthalenes.
Topics: Animals; Anti-Inflammatory Agents; Chalcone; Female; Indomethacin; Lethal Dose 50; Male; Mice; Napht | 2001 |
Influence of dietary protein on the anti-inflammatory and ulcerogenic effects and on the pharmacokinetics of phenylbutazone in rats.
Topics: Animals; Body Weight; Carrageenan; Dietary Proteins; Edema; Kinetics; Male; Phenylbutazone; Protein- | 1979 |
The action of azapropazone, oxyphenbutazone and phenylbutazone on lysosomes.
Topics: Acid Phosphatase; Animals; Female; Glycoside Hydrolases; Histocytochemistry; Ileum; In Vitro Techniq | 1971 |
Necrotizing scleral degeneration treated with a graft of autogenous fascia lata.
Topics: Aged; Conjunctiva; Eye Diseases; Fascia; Female; Humans; Necrosis; Panophthalmitis; Phenylbutazone; | 1970 |
3-phenylcinnolines. II. The preparation of 4-amino derivatives.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Chemistry, Organic; Dicarboxylic Acids; Diuresis; | 1966 |
3-phenylcinnolines. I. Some reactions and derivatives of 3-phenylcinnoline-4-carboxylic acids.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Blood Pressure; Chemistry, Organic; Dicarboxylic A | 1966 |