Page last updated: 2024-11-02

phenylbutazone and Gastric Ulcer

phenylbutazone has been researched along with Gastric Ulcer in 180 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
" Anecdotally, many practitioners prescribe omeprazole concurrently with phenylbutazone to reduce development of equine gastric ulcer syndrome (EGUS), but the efficacy and safety of this practice remains unknown."9.41Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS). ( Andrews, FM; Banse, HE; Chapman, A; Garza, F; Keowen, M; Paul, L; Ricord, M; Yñiguez, FJM, 2021)
"The effect of bromocriptine, a dopamine receptor agonist, has been studied on the aspirin, phenylbutazone and reserpine induced gastric ulcers in rats."7.67Effect of bromocriptine, a dopamine receptor agonist, on the experimentally induced gastric ulcers in albino rats. ( Ageel, AM; Parmar, NS; Tariq, M, 1984)
"The interaction between reserpine and nonsteroidal anti-inflammatory agents ( NSAIA ) in producing experimental gastric ulcers was studied in rats."7.67Interaction between reserpine and non-steroidal anti-inflammatory agents in producing gastric ulcers in rats. ( Radmanović, BZ; Sćepović, Z, 1984)
" The effects of sulphasalazine (SZP) and PhCL28A on macroscopic lesion formation and ex vivo prostaglandin inactivation were studied in the ethanol (ETOH) and phenylbutazone (PBT) models of gastric ulcers in the rat."7.67Sulphasalazine and PhCL28A inhibit the formation of ethanol- and phenylbutazone-induced rat gastric ulcers: lack of involvement of endogenous prostaglandins? ( Berry, CN; Lloyd, KG; Prouteau, M, 1988)
"The effect of domperidone, a peripheral dopamine receptor antagonist, has been studied in the aspirin, phenylbutazone and reserpine induced gastric ulcers in rats."7.67Effect of domperidone on experimentally induced gastric ulcers in rats. ( Ageel, AM; Al-Khamis, KI; Parmar, NS; Tariq, M, 1986)
"Phenylbutazone has been shown to alter GI barrier function both in vitro and ex vivo, but its effects on barrier function have not been assessed in vivo."7.01Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses. ( Bradbery, A; Chamoun-Emanuelli, AM; Cohen, ND; Coleman, MC; DeSolis, CN; Much, M; Sowinski, R; Tetrault, T; Whitfield-Cargile, CM, 2021)
" Anecdotally, many practitioners prescribe omeprazole concurrently with phenylbutazone to reduce development of equine gastric ulcer syndrome (EGUS), but the efficacy and safety of this practice remains unknown."5.41Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS). ( Andrews, FM; Banse, HE; Chapman, A; Garza, F; Keowen, M; Paul, L; Ricord, M; Yñiguez, FJM, 2021)
" One group received a high dose of PBZ for two weeks; the second group was given an equimolecular dosage of SBZ; and a third group received placebo."5.32Lower gastric ulcerogenic effect of suxibuzone compared to phenylbutazone when administered orally to horses. ( Homedes, J; Mayós, I; Monreal, L; Sabaté, D; Segura, D, 2004)
"Although both classes of NSAID induced gastric ulceration, the COX-2 selective NSAID firocoxib induced less severe glandular ulceration."3.88Effect of selective versus nonselective cyclooxygenase inhibitors on gastric ulceration scores and intestinal inflammation in horses. ( Chamoun-Emanuelli, AM; Cohen, ND; Dockery, HJ; Richardson, LM; Whitfield-Cargile, CM, 2018)
" Pre-treatment with the extract (100, 200 and 400 mg/kg) produced a significant and dose-dependent inhibition to the acute gastric ulcers induced by phenylbutazone, indomethacin, 0."3.71Anti-inflammatory and anti-ulcer activity of Calligonum comosum in rats. ( Al-Attas, A; Chan, K; Chen, HB; Islam, MW; Ismail, A; Liu, XM; Radhakrishnan, R; Zakaria, MN, 2001)
" The antiulcer activity of vinpocetine was demonstrated also in gastric injury induced by phenylbulazone and in chronic gastric ulcer induced by acetic acid."3.68Protective action of vinpocetine against experimentally induced gastric damage in rats. ( Babulová, A; Machová, J; Nosálová, V, 1993)
" The lesions of the gastric mucosa were caused in three groups: by stress through swimming-test, by application of phenylbutazone, and by ischemia (ligature of the left gastric and the right gastroepiploic vessels)."3.68[The effect of proximal selective vagotomy on experimental gastric mucosal lesions in the rat]. ( Cerný, J; Daniś, J; Nosálová, V, 1990)
"Combined treatment with the H2 antagonist ranitidine and the cytoprotective agent pentacaine was studied in acute gastric lesions induced by phenylbutazone and stress, in chronic gastric ulcers induced by acetic acid, and in Shay's model of gastric secretion stimulated by histamine."3.68Efficacy of combined ranitidine and pentacaine treatment in experimentally induced gastric damage in rats. ( Babul'ová, A; Benes, L; Nosál'ová, V, 1990)
" I-L increased the mucopolysaccharide contents (hexosamine, uronic and sialic acids) in the gastric mucosa of intact rats and inhibited the decrease of mucopolysaccharide contents in the gastric mucosa of rats with phenylbutazone-induced gastric ulcers."3.67Studies on pharmacological activation of human serum immunoglobulin G by chemical modification and active subfragments. III. Mechanism of anti-ulcerous action of alkylated light chain (Fr. I-L). ( Aonuma, S; Iwai, M; Kohda, I; Maeda, K; Mimura, T; Tsujikawa, K, 1984)
"The effect of bromocriptine, a dopamine receptor agonist, has been studied on the aspirin, phenylbutazone and reserpine induced gastric ulcers in rats."3.67Effect of bromocriptine, a dopamine receptor agonist, on the experimentally induced gastric ulcers in albino rats. ( Ageel, AM; Parmar, NS; Tariq, M, 1984)
"The interaction between reserpine and nonsteroidal anti-inflammatory agents ( NSAIA ) in producing experimental gastric ulcers was studied in rats."3.67Interaction between reserpine and non-steroidal anti-inflammatory agents in producing gastric ulcers in rats. ( Radmanović, BZ; Sćepović, Z, 1984)
" The effects of sulphasalazine (SZP) and PhCL28A on macroscopic lesion formation and ex vivo prostaglandin inactivation were studied in the ethanol (ETOH) and phenylbutazone (PBT) models of gastric ulcers in the rat."3.67Sulphasalazine and PhCL28A inhibit the formation of ethanol- and phenylbutazone-induced rat gastric ulcers: lack of involvement of endogenous prostaglandins? ( Berry, CN; Lloyd, KG; Prouteau, M, 1988)
" The anti-inflammatory properties of FPP028 were evaluated through the carrageenan induced paw edema and the cotton pellet induced granuloma and compared with the activity of indomethacin, phenylbutazone, and isoxicam; as a result, the activity of FPP028 was shown to be similar to that of the latter compounds."3.67Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent. ( Banchelli, G; Bianchini, F; Ignesti, G; Pecori-Vettori, L; Pirisino, R; Rafanelli, D; Raimondi, L, 1986)
"The effect of domperidone, a peripheral dopamine receptor antagonist, has been studied in the aspirin, phenylbutazone and reserpine induced gastric ulcers in rats."3.67Effect of domperidone on experimentally induced gastric ulcers in rats. ( Ageel, AM; Al-Khamis, KI; Parmar, NS; Tariq, M, 1986)
"The nonsteroid anti-inflammatory drugs including phenylbutazone produce significant gastric ulceration and hemorrhage even when administered by an extragastric route."3.66Synergism between acid and gastric contractile activity in the genesis of ulceration and hemorrhage in the phenylbutazone-treated rat. ( Hinchey, EJ; Mersereau, WA, 1981)
" In the carrageenan edema test, eight compounds exhibited higher antiinflammatory activities than did indomethacin."3.656,11-Dihydro-11-oxodibenz [b,e] oxepinacetic acids with potent antiinflammatory activity. ( Kubo, S; Tagawa, H; Tsukada, W; Ueno, K; Yoshioka, T, 1976)
"Phenylbutazone has been shown to alter GI barrier function both in vitro and ex vivo, but its effects on barrier function have not been assessed in vivo."3.01Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses. ( Bradbery, A; Chamoun-Emanuelli, AM; Cohen, ND; Coleman, MC; DeSolis, CN; Much, M; Sowinski, R; Tetrault, T; Whitfield-Cargile, CM, 2021)
" One group received a high dose of PBZ for two weeks; the second group was given an equimolecular dosage of SBZ; and a third group received placebo."1.32Lower gastric ulcerogenic effect of suxibuzone compared to phenylbutazone when administered orally to horses. ( Homedes, J; Mayós, I; Monreal, L; Sabaté, D; Segura, D, 2004)
"Phenylbutazone is a nonsteroidal anti-inflammatory drug that was commonly prescribed for the treatment of arthritic conditions; it is no longer available for use in humans because of its numerous side effects, including aplastic anemia."1.29Misuse of veterinary phenylbutazone. ( Carpenter, SL; McDonnell, WM, 1995)
"Aceclofenac is a new phenylacetic acid derivative provided with marked antiinflammatory, antiarthritic, analgesic and antipyretic activities in animal experimental models."1.28The pharmacological profile of aceclofenac, a new nonsteroidal antiinflammatory and analgesic drug. ( Carrasco, E; Felipe, A; Grau, M; Guasch, J; Juliá, S; Montero, JL, 1991)
"Phenylbutazone (PBZ) is a nonsteroidal antiinflammatory drug (NSAID) that is not commonly prescribed due to the high incidence of serious adverse reactions."1.27Horse pill ("bute") hemorrhage. ( Cohen, ML; Davis, M; Gogel, HK; Ming, RH; Pitcher, JL, 1988)
"Pretreatment with nicotine, caffeine, and their combination resulted in significant augmentation of gastric ulcers produced by aspirin, phenylbutazone, and reserpine."1.27Effect of nicotine and caffeine pretreatment on the gastric mucosal damage induced by aspirin, phenylbutazone, and reserpine in rats. ( Ageel, AM; Parmar, NS; Tariq, M, 1985)
"Pretreatment with nicotine, alcohol and caffeine and their combination resulted in a significant augmentation of gastric lesions produced by aspirin, phenylbutazone and reserpine."1.27Effect of nicotine, alcohol and caffeine pretreatment on the gastric mucosal damage induced by aspirin, phenylbutazone and reserpine in rats. ( Ageel, AM; Parmar, NS; Tariq, M, 1985)
" The degree of gastric or intestinal irritation seen with dosing of other drugs was as follows; indomethacin greater than diclofenac Na greater than ibuprofen greater than aspirin greater than phenylbutazone or indomethacin greater than CH-800 = diclofenac Na greater than ibuprofen greater than phenylbutazone, respectively."1.26[Irritative activity of a new anti-inflammatory agent 4-(p-chorophenyl)-2-phenyl-5-thiazoleacetic acid (CH-800) on the gastrointestinal tract in rats (author's transl)]. ( Ohtsuki, H; Okabe, S; Tabata, K, 1979)
"Butibufen was within the potency range of ibuprofen as an antipyretic and analgesic agent and greater than that of acetylsalicylic acid."1.26Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent. ( Aparicio, L, 1977)
" Thiazolinobutazone was the less toxic (acute LD50) and the less ulcerogenic molecule of the two and, in contrast to phenylbutazone, was not antidiuretic."1.26Pharmacological properties of thiazolinobutazone (LAS 11 871). III. General pharmacology, ulcerogenic effects and acute toxicity. ( Colombo, M; Márquez, M; Roberts, DJ, 1976)

Research

Studies (180)

TimeframeStudies, this research(%)All Research%
pre-1990156 (86.67)18.7374
1990's12 (6.67)18.2507
2000's8 (4.44)29.6817
2010's2 (1.11)24.3611
2020's2 (1.11)2.80

Authors

AuthorsStudies
Nagakura, M1
Ota, T1
Shimidzu, N1
Kawamura, K1
Eto, Y1
Wada, Y1
Krapcho, J1
Turk, CF1
Ueno, K1
Kubo, S1
Tagawa, H1
Yoshioka, T1
Tsukada, W1
Asselin, AA1
Humber, LG2
Dobson, TA1
Komlossy, J1
Martel, RR1
Demerson, CA1
Philipp, AH1
Toja, E1
Selva, D1
Schiatti, P1
Tsukamoto, G1
Yoshino, K1
Kohno, T1
Ohtaka, H1
Kagaya, H1
Ito, K1
Kumar, A2
Rajput, CS1
Bhati, SK1
Venu, TD1
Shashikanth, S1
Khanum, SA1
Naveen, S1
Firdouse, A1
Sridhar, MA1
Shashidhara Prasad, J1
Ricord, M1
Andrews, FM2
Yñiguez, FJM1
Keowen, M1
Garza, F1
Paul, L1
Chapman, A1
Banse, HE1
Whitfield-Cargile, CM2
Coleman, MC1
Cohen, ND2
Chamoun-Emanuelli, AM2
DeSolis, CN1
Tetrault, T1
Sowinski, R1
Bradbery, A1
Much, M1
Richardson, LM1
Dockery, HJ1
Martínez Aranzales, JR1
Cândido de Andrade, BS1
Silveira Alves, GE1
Reinemeyer, CR1
Longhofer, SL1
Sharma, S1
Srivastava, VK1
Muniappan, M1
Sundararaj, T1
RAFFENSPERGER, EC1
KRAININ, P1
BONFILS, S2
HARDOUIN, JP2
BOUREL, M1
DELBARRE, F1
LA BARRE, J3
DESMAREZ, JJ1
FIORENTINO, G1
PASQUI, E1
TRAUT, EF1
WATT, J1
WILSON, CW1
HERKELOVA, L1
SANYAL, AK2
GUPTA, KK2
CHOWDHURY, NK2
SINGH, GB1
ZAIDI, SH1
BAJPAI, RP1
BRODIE, DA1
MARSHALL, RW1
MORENO, OM1
CAHEN, R1
PESSONNIER, A1
VARRO, V1
JUNG, I1
CSERNAY, L1
LALICATA, D1
DENKO, CW1
LIBRO, V1
MURARI, G1
GUERRIN, F2
CLAY, A1
LHERMINE, C1
DEMAILLE, A1
DRUART, R1
BOCCA, C1
DELORE, J1
Monreal, L1
Sabaté, D1
Segura, D1
Mayós, I1
Homedes, J1
Reed, SK1
Messer, NT1
Tessman, RK1
Keegan, KG1
Villar, A1
Gasco, MA1
Alcaraz, MJ1
Mimura, T4
Iwai, M3
Maeda, K4
Kohda, I3
Tsujikawa, K2
Aonuma, S4
Mersereau, WA2
Hinchey, EJ2
Pande, K1
Tandon, P1
Bhalla, TN2
Tangri, KK1
Parmar, SS1
Barthwal, JP1
Mokhort, NA1
Nazarenko, NN1
Kondratiuk, VI1
Terada, T2
Driscoll, P1
Kugler, P1
Parmar, NS5
Tariq, M4
Ageel, AM4
Chojnacka-Wójcik, E1
Naparzewska, A1
Catto, A1
Cappelletti, R1
Leonardi, A1
Maggi, F1
Tajana, A1
Nardi, D1
Traub, JL1
Gallina, AM1
Grant, BD1
Reed, SM1
Gavin, PR1
Paulsen, LM1
Sasaki, Y1
Momose, T1
Aleshin, VP1
Putiatin, SV1
Sćepović, Z1
Radmanović, BZ1
Diamantis, W2
Melton, J1
Sofia, RD2
Ciofalo, VB1
Okamoto, S2
Arima, T2
Amioka, I2
Nagashima, H2
Neuschl, J5
Kohút, A11
Nicák, A10
Tanaka, H1
Shuto, K1
Nakamizo, N1
Felder, M1
Ghosh, MN1
Ohnaus, EE1
Frösch, R1
Satoh, H1
Inada, I1
Hirata, T1
Maki, Y1
Faurel, JP1
Delas, N1
Saigot, T1
Sarrazin, A1
Okabe, S2
Kunimi, H1
Verma, M1
Sinha, JN1
Gujrati, VR1
Bhargava, KP1
Shanker, K1
Labrid, C3
Dureng, G3
Boero, C2
Duchene-Marullaz, P1
Carpenter, SL1
McDonnell, WM1
Nosál'ová, V3
Babul'ová, A3
Vigorita, MG1
Grasso, S1
Zappalà, M1
Ottanà, R1
Monforte, MT1
Barbera, R1
Trovato, A1
Nosálová, V2
Machová, J1
Babulová, A1
Benes, L2
el-Hawash, SA1
el-Mallah, AI1
Zelenin, KN1
Bezhan, IP1
Pastushenkov, LV1
Gromova, EG1
Lesiovskaja, EE1
Chakchir, BA1
Melnikova, LF1
Liu, XM1
Zakaria, MN1
Islam, MW1
Radhakrishnan, R1
Ismail, A1
Chen, HB1
Chan, K1
Al-Attas, A1
Cashin, CH1
Dawson, W1
Kitchen, EA1
Wiggins, LF1
Menguy, R1
Valentík, M1
Visnovský, P1
Delort, P1
Chopard, M1
Courcy, J1
Sieck, A2
Tabata, K1
Ohtsuki, H1
Wenzl, H1
Graf, E1
Djahanguiri, B1
Zarrindast, MR1
Gerayesh-Nejad, S1
Ofuji, T1
Kudo, M1
Okumura, M1
Grau, M3
Flos, R1
Beltran, J1
Balasch, J1
Cooke, AR2
Wigley, RA1
Fowles, M1
Ancill, RJ1
Aparicio, L1
Suzuki, Y1
Hayashi, M1
Ito, M1
Yamagami, I1
Colombo, M1
Márquez, M1
Roberts, DJ1
Biliotti, G7
Marsili, M1
Lorenzi, P1
Pernice, LM1
Canestrini, C1
Testa, R1
Reschiotto, C1
Fanelli, O1
Ostapchuk, NV1
Guasch, J2
Montero, JL2
Felipe, A2
Carrasco, E2
Juliá, S2
Daniś, J1
Cerný, J1
Puscas, I2
Hajdu, A1
Buzás, G1
Bernáth, Z1
Vittorio, F1
Pappalardo, MS1
Ronsisvalle, G1
Caruso, A1
Leone, MG1
Amico-Roxas, M1
Berry, CN1
Prouteau, M1
Lloyd, KG1
Cohen, ML1
Ming, RH1
Gogel, HK1
Davis, M1
Pitcher, JL1
Pirisino, R1
Bianchini, F1
Banchelli, G1
Ignesti, G1
Raimondi, L1
Pecori-Vettori, L1
Rafanelli, D1
Escolar, G1
Camarasa, J1
Navarro, C1
Vernetta, C1
Bulbena, O1
Al-Khamis, KI1
Oda, Y1
Morishita, K1
Takagi, K1
Abe, Y1
Palasz, M1
Murmann, W2
Carminati, GM3
Cattaneo, R2
Merveille, P1
L'Hermine, C1
Decoulx, M1
Schwartz, JC1
Boulu, R1
Valette, G1
Chapman, BL1
Duggan, JM1
Vasilenko, VKh1
Tsodikov, GV1
Minushkin, ON1
Delaveirre, PH1
Hureau, J1
Grivaux, M1
Chretien, J1
Etienne, JP1
Cosh, JA1
Cioli, V1
Silvestrini, B1
Dordoni, F1
Ezer, E1
Szporny, L1
Coppi, G3
Bonardi, G2
Gaetani, M3
Wilhelmi, G1
Veress, S1
Resiga, C1
Bennett, PN1
Narumi, S2
Kanno, M2
Furnemont, E1
Fichera, G1
Mirelli, E1
Gordon, R1
Kletzkin, M1
Berger, FM1
Edelson, J1
Singer, H1
Douglas, JF1
Arnold, L1
Collins, C1
Starmer, GA1
Kuzuna, S1
Matsumoto, N1
Kawai, K1
Cheli, R1
Ciancamerla, G1
Debeus, R1
Chiabotto, L1
Duzzi, L1
Larmi, TK3
Kairaluoma, MI3
Kuhn, D1
Sun, DC1
Roth, SH1
Mitchell, CS1
Englund, DW1
Dagradi, AE1
Falkner, RE1
Lee, ER1
Kuschinsky, G1
Takashima, T1
Kado, Y1
Kumada, S1
Pallarès, J1
Scarselli, V1
Pallavicini, G1
Cetta, G1
Quaroni, A1
Castellani, AA1
Cosen, JN1
Cosen, RH1
Pascaud, X1
Laubie, M1
Alechinsky, A1
Matsumoto, T1
Barroy, JP1
Willems, G1
Verbeustel, S1
Gerard, A1
Nakamura, H1
Soji, Y1
Masuda, Y1
Nakamura, K1
Angelov, AG1
Bakhariev, Z1
Bucciarelli, G5
Andreoli, F5
Pirani, A3
Mori, V2
Baroni, A1
Marazzi-Uberti, E1
Abdel-Galil, AA1
Marshall, PB1
Teutsch, W1
Jahn, U1
Adrian, RW1
Mazure, PA1
Rotman, JM1
Dobrescu, D1
Derouaux, G1
Oleffe-Koopmansch, S1
Moisse, R1
Bassarelli, V2
Masi, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Open Label, Randomized, Single Site Clinical Trial To Compare The Safety Of Herbal Melanin Extracted From Nigella Sativa Seeds Vs Standard Of Care Treatment In Treating Gastritis Patients[NCT03428568]Phase 2132 participants (Anticipated)Interventional2018-03-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for phenylbutazone and Gastric Ulcer

ArticleYear
[Pharmacological properties of pyrazolone and pyrazolidine derivatives (review of the literature)].
    Vrachebnoe delo, 1984, Issue:3

    Topics: Aminopyrine; Anaphylaxis; Animals; Anti-Inflammatory Agents; Dipyrone; Fibrinogen; Humans; Kidney Di

1984
The chemical and biological background to alclofenac.
    Current medical research and opinion, 1975, Volume: 3, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Dogs; Female; Guinea P

1975
[Mechanism of the ulcerogenic effects of phenylbutazone and indomethacin].
    Ceskoslovenska gastroenterologie a vyziva, 1978, Volume: 32, Issue:8

    Topics: Adrenalectomy; Animals; Female; Gastric Juice; Gastric Mucosa; Guinea Pigs; Histidine Decarboxylase;

1978
The role of the mucosal barrier in drug-induced gastric ulceration and erosions.
    The American journal of digestive diseases, 1976, Volume: 21, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Ethanol; Gastric Juice; Gastric Mucosa;

1976
Analgesics and the stomach.
    The New Zealand medical journal, 1976, Aug-11, Volume: 84, Issue:569

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Indometha

1976
[Effect of some drugs in the development and exacerbation of gastric and duodenal ulcer].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1974, Jun-15, Volume: 27, Issue:12

    Topics: Adrenocorticotropic Hormone; Aspirin; Caffeine; Catecholamines; Duodenal Ulcer; Fluorouracil; Glucoc

1974
[Effect of some antirheumatic agents on the gastric mucous membrane].
    Klinicheskaia meditsina, 1971, Volume: 49, Issue:8

    Topics: Adrenocorticotropic Hormone; Aged; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheuma

1971

Trials

5 trials available for phenylbutazone and Gastric Ulcer

ArticleYear
Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS).
    Equine veterinary journal, 2021, Volume: 53, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Horses; Omeprazole; Phenylbutazone

2021
Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Horses; Microbiota; Permeability;

2021
Effects of top-dress formulations of suxibuzone and phenylbutazone on development of gastric ulcers in horses.
    Veterinary therapeutics : research in applied veterinary medicine, 2009,Fall, Volume: 10, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; F

2009
Effects of phenylbutazone alone or in combination with flunixin meglumine on blood protein concentrations in horses.
    American journal of veterinary research, 2006, Volume: 67, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Clonixin; Drug Therapy, Combinatio

2006
Prevention of non-steroidal anti-inflammatory agents induced acute gastric mucosal lesions by carbonic anhydrase inhibitors. An endoscopic study.
    Acta physiologica Hungarica, 1989, Volume: 73, Issue:2-3

    Topics: Acetazolamide; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastroscopy;

1989

Other Studies

168 other studies available for phenylbutazone and Gastric Ulcer

ArticleYear
Syntheses and antiinflammatory actions of 4,5,6,7-tetrahydroindazole-5-carboxylic acids.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Edema; Indazole

1979
Bicyclic pyrazolines, potential central nervous system depressants and antiinflammatory agents.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Central Nervous System Depressants; Edema; Female; M

1979
6,11-Dihydro-11-oxodibenz [b,e] oxepinacetic acids with potent antiinflammatory activity.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:7

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dibenzoxepins; Edema; Female; Le

1976
Cycloalkanoindoles. 1. Syntheses and antiinflammatory actions of some acidic tetrahydrocarbazoles, cyclopentindoles, and cycloheptindoles.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Cycloheptanes; Cyclopentanes;

1976
Etodolic acid and related compounds. Chemistry and antiinflammatory actions of some potent di- and trisubstituted 1, 3, 4, 9-tetrahydropyrano[3, 4-b]indole-1-acetic acids.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carrageenan; Freund's Adjuvant; Indoleacet

1976
3-Alkyl-2-aryl-3H-naphth[1,2-d]imidazoles, a novel class of nonacidic antiinflammatory agents.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Drug Evaluation, Preclini

1984
Synthesis and antiinflammatory activity of some 2-(substituted-pyridinyl)benzimidazoles.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Cyclooxy

1980
Synthesis of 3-[4'-(p-chlorophenyl)-thiazol-2'-yl]-2-[(substituted azetidinone/thiazolidinone)-aminomethyl]-6-bromoquinazolin-4-ones as anti-inflammatory agent.
    Bioorganic & medicinal chemistry, 2007, Apr-15, Volume: 15, Issue:8

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azetidines; Dose-Response Relationshi

2007
Synthesis and crystallographic analysis of benzophenone derivatives--the potential anti-inflammatory agents.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Carrageenan; Crystallography, X-Ray

2007
Effect of selective versus nonselective cyclooxygenase inhibitors on gastric ulceration scores and intestinal inflammation in horses.
    Veterinary surgery : VS, 2018, Volume: 47, Issue:6

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Fece

2018
Orally administered phenylbutazone causes oxidative stress in the equine gastric mucosa.
    Journal of veterinary pharmacology and therapeutics, 2015, Volume: 38, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Dinoprostone; Fema

2015
Anti-inflammatory activity of some novel alpha-amino naphthalene derivatives.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chemical Phenomena; Chemistry, Physic

2003
Antiinflammatory and antiulcer activities of Bambusa arundinacea.
    Journal of ethnopharmacology, 2003, Volume: 88, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Bambusa; Carrageenan;

2003
Multiple gastric ulcers occurring during phenylbutazone therapy.
    Journal of the American Medical Association, 1953, May-02, Volume: 152, Issue:1

    Topics: Analgesics; Humans; Peptic Ulcer; Phenylbutazone; Stomach Ulcer

1953
Gastric ulcer with massive hemorrhage following use of phenylbutazone; report of a case.
    Journal of the American Medical Association, 1953, May-02, Volume: 152, Issue:1

    Topics: Analgesics; Hemorrhage; Peptic Ulcer; Phenylbutazone; Stomach Ulcer

1953
[Gastric ulcer in the rat by ingestion of phenylbutazone].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1953, Volume: 147, Issue:23-24

    Topics: Analgesics; Animals; Eating; Peptic Ulcer; Phenylbutazone; Rats; Stomach Ulcer

1953
[Gastric ulceration in white rats caused by administration of phenylbutazone; study of mechanism of action].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1954, Volume: 148, Issue:9-10

    Topics: Analgesics; Animals; Peptic Ulcer; Phenylbutazone; Rats; Stomach Ulcer

1954
[Inhibiting effects of khellin on experimental gastric ulcer induced by daily administration of phenylbutazone].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:10

    Topics: Khellin; Peptic Ulcer; Phenylbutazone; Stomach Ulcer

1956
[Gastric ulcer from phenylbutazone].
    Giornale italiano di chirurgia, 1957, Volume: 13, Issue:9

    Topics: Humans; Peptic Ulcer; Phenylbutazone; Stomach Ulcer

1957
Gastric ulcer during steroid therapy in a patient with persistent achlorhydria: effects of antirheumatic medication.
    Annals of internal medicine, 1958, Volume: 49, Issue:6

    Topics: Achlorhydria; Antirheumatic Agents; Arthritis; Arthritis, Rheumatoid; Gastric Juice; Humans; Medical

1958
Phenylbutazone and gastric ulceration in the guinea pig.
    Gastroenterology, 1959, Volume: 37, Issue:1

    Topics: Guinea Pigs; Peptic Ulcer; Phenylbutazone; Stomach Ulcer

1959
[Effect of epinephrectomy on the appearance of phenylbutazone gastric ulcer in rats].
    Ceskoslovenska fysiologie, 1960, Volume: 9

    Topics: Adrenalectomy; Animals; Peptic Ulcer; Phenylbutazone; Rats; Stomach Ulcer

1960
Banana and experimental peptic ulcer.
    The Journal of pharmacy and pharmacology, 1963, Volume: 15

    Topics: Antacids; Flavoring Agents; Fruit; Musa; Peptic Ulcer; Phenylbutazone; Stomach Ulcer

1963
Effect of Brassica oleracea var. Capitata in the prevention and healing of experimental peptic ulceration.
    The Indian journal of medical research, 1962, Volume: 50

    Topics: Amine Oxidase (Copper-Containing); Brassica; Humans; Peptic Ulcer; Phenylbutazone; Stomach Ulcer; Ve

1962
The effect of ulcerogenic drugs on gastric acidity in the rat with chronic fistula.
    Gastroenterology, 1962, Volume: 43

    Topics: Animals; Digestion; Fistula; Gastric Fistula; Phenylbutazone; Polymyxins; Prednisolone; Rats; Reserp

1962
[Pharmacological study of dihydroxyaluminum allantoinate and chlorhydroxyaluminum allantoinate. IV. Effect on experimental drug-induced ulcer].
    Annales pharmaceutiques francaises, 1963, Volume: 21

    Topics: Allantoin; Aluminum Hydroxide; Antacids; Drugs, Investigational; Phenylbutazone; Reserpine; Stomach

1963
[THE SIGNIFICANCE OF PITUITARY-ADRENAL AXIS IN THE PATHOGENESIS OF EXPERIMENTAL PHENYLBUTAZONE ULCER].
    Kiserletes orvostudomany, 1963, Volume: 15

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Cortisone; Desoxycorticosterone; Dogs; Phenylbutazone;

1963
[ASPECTS OF THE ANTICHOLINERGIC ACTION OF A NEW SPASMOLYTIC: 1-ALPHA-THIENYL-1-PHENYL-3-N-METHYLMORPHOLINE-1-PROPANOL IODIDE].
    La Clinica terapeutica, 1963, Oct-15, Volume: 27

    Topics: 1-Propanol; Acetylcholine; Blood Circulation; Blood Pressure; Blood Pressure Determination; Choliner

1963
THE EFFECT OF PHENYLBUTAZONE AND ITS DERIVATIVES OXYPHENBUTAZONE AND SULFINPYRAZONE ON S-35-SULFATE INCORPORATION IN CARTILAGE AND STOMACH.
    The Journal of laboratory and clinical medicine, 1964, Volume: 63

    Topics: Cartilage; Hypophysectomy; Metabolism; Oxyphenbutazone; Pharmacology; Phenylbutazone; Rats; Research

1964
STUDIES ON PEPTIC ULCERATION. I. ROLE OF BANANA IN PHENYLBUTAZONE INDUCED ULCERS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jun-01, Volume: 149

    Topics: Diet; Flavoring Agents; Fruit; Guinea Pigs; Musa; Pathology; Peptic Ulcer; Phenylbutazone; Research;

1964
[FINDINGS ON GASTRIC MODIFICATIONS INDUCED BY PYRAZOLIDINIC DERIVATIVES].
    L' Ospedale maggiore, 1964, Volume: 59

    Topics: Gastric Mucosa; Oxyphenbutazone; Phenylbutazone; Rats; Research; Stomach Ulcer; Toxicology

1964
PHARMACOLOGICAL INVESTIGATION ON GEFARNATE, A NEW SYNTHETIC COMPOUND AGAINST GASTRIC ULCER.
    Medicina experimentalis : International journal of experimental medicine, 1964, Volume: 11

    Topics: Gefarnate; Pharmacology; Phenylbutazone; Prednisolone; Rats; Research; Stomach Ulcer; Terpenes; Toxi

1964
[THE ACTION OF AN ENZYMATIC INHIBITOR ON GASTRIC LESIONS CAUSED BY PHENYLBUTAZONE IN THE RAT].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Enzyme Inhibitors; Gastric Mucosa; Pathology; Pharmacology; Phenylbutazone; Rats; Research; Stomach

1964
[A case of perforation of gastric ulcer after two injections of phenylbutazone].
    Archives des maladies de l'appareil digestif et des maladies de la nutrition, 1955, Volume: 44, Issue:2

    Topics: Analgesics; Humans; Injections; Peptic Ulcer Perforation; Phenylbutazone; Sciatica; Stomach Ulcer

1955
Lower gastric ulcerogenic effect of suxibuzone compared to phenylbutazone when administered orally to horses.
    Research in veterinary science, 2004, Volume: 76, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastric Mucosa; Horse Diseases; Horses; Ma

2004
Anti-inflammatory and anti-ulcer properties of hypolaetin-8-glucoside, a novel plant flavonoid.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:12

    Topics: Abscess; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agen

1984
Studies on pharmacological activation of human serum immunoglobulin G by chemical modification and active subfragments. III. Mechanism of anti-ulcerous action of alkylated light chain (Fr. I-L).
    Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:10

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Fasting; Fibrinolysis; Gastric Mucosa; Glycosaminoglycans; Immu

1984
Prevention of phenylbutazone ulcer in the rat by glucose: role of a glycoprivic receptor system.
    The American journal of physiology, 1982, Volume: 242, Issue:4

    Topics: Animals; Female; Fructose; Gastrointestinal Hemorrhage; Glucose; Mannitol; Muscle Contraction; Pheny

1982
Substituted triazoles as anti-inflammatory agents.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 45, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chem

1984
Studies on pharmacological activation of human serum IgG by chemical modification and active subfragments. II. Inhibitory effects of carboxamide-methylated L chain from human serum IgG on various ulcer models and its inhibition mechanism.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:7

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Hexosamines; Humans; Immunoglobulin G; Immunoglobulin Light Cha

1983
Genetic and histological aspects of stomach lesions induced by systemic injection of phenylbutazone in the rat.
    Experientia, 1984, Sep-15, Volume: 40, Issue:9

    Topics: Animals; Avoidance Learning; Food Deprivation; Male; Phenylbutazone; Rats; Rats, Mutant Strains; Sto

1984
Effect of bromocriptine, a dopamine receptor agonist, on the experimentally induced gastric ulcers in albino rats.
    Life sciences, 1984, Nov-12, Volume: 35, Issue:20

    Topics: Animals; Aspirin; Bromocriptine; Female; Gastric Mucosa; Male; Phenylbutazone; Rats; Rats, Inbred St

1984
Pharmacological properties of the antiinflammatory agent 10-methylamine-11-H-indeno-[1,2-b]quinolin-11-one (MB432).
    Polish journal of pharmacology and pharmacy, 1983, Volume: 35, Issue:4

    Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Indomet

1983
[Indolin-2,3-dione-3,N-alkylamino- and 3,N-piperazinoacetylhydrazones, new substances with anti-ulcer and antisecretory activity].
    Il Farmaco; edizione scientifica, 1983, Volume: 38, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Chemical Phenomena; Chemistry; Female; Gastric Juice; Hydrazones; Mice;

1983
Phenylbutazone toxicosis in the foal.
    American journal of veterinary research, 1983, Volume: 44, Issue:8

    Topics: Animals; Barium Sulfate; Colonic Diseases; Diarrhea; Female; Gastric Mucosa; Gastroscopy; Horse Dise

1983
Inhibitory effects of unsaturated fatty acids of trans-2-C10:1 to trans-2-C16:1 several C18:n and C20:n on gastric secretion and experimental ulceration in rats.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:8

    Topics: Animals; Aspirin; Capillary Permeability; Fatty Acids, Unsaturated; Gastric Emptying; Gastric Juice;

1983
[Perforated stomach ulcer in a patient treated with pirabutol].
    Klinicheskaia khirurgiia, 1984, Issue:3

    Topics: Aminopyrine; Arthritis, Rheumatoid; Drug Combinations; Female; Humans; Middle Aged; Peptic Ulcer Per

1984
Interaction between reserpine and non-steroidal anti-inflammatory agents in producing gastric ulcers in rats.
    European journal of pharmacology, 1984, Mar-02, Volume: 98, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Synergism; Female; Indomet

1984
Comparative gastric ulcerogenic effects of meseclazone, 5-chlorosalicylic acid and other nonsteroidal anti-inflammatory drugs following acute and repeated oral administration to rats.
    Toxicology and applied pharmacology, 1980, Mar-15, Volume: 52, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Benzoxazines; Biotransformation; Fenoprofen; Ibuprofen; Indometha

1980
[Studies on biosynthesis of gastric glycoprotein in the rat gastric mucosal damage. II. Studies on UDP-galactosyl transferase activity in the rat gastric mucosal damage by phenylbutazone (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1981, Volume: 78, Issue:4

    Topics: Animals; beta-N-Acetylglucosaminylglycopeptide beta-1,4-Galactosyltransferase; Galactosyltransferase

1981
[The effect of calcium chloride on the ulcerogenic effects of phenylbutazone and reserpine in relation to the calcium content of the stomach wall in rats of various ages].
    Ceskoslovenska gastroenterologie a vyziva, 1983, Volume: 37, Issue:2

    Topics: Animals; Calcium; Calcium Chloride; Female; Gastric Mucosa; Male; Phenylbutazone; Rats; Rats, Inbred

1983
Exacerbation of acetic acid ulcer induced by non-steroidal anti-inflammatory drugs in rats.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents; Aspirin; Gastric Emptying; Gastric Juice;

1983
[Non-steroidal antirheumatics: side-effects and interactions].
    Schweizerische medizinische Wochenschrift, 1982, Aug-28, Volume: 112, Issue:35

    Topics: Anemia, Aplastic; Anti-Inflammatory Agents, Non-Steroidal; Coumarins; Drug Interactions; Gastrointes

1982
[Studies on gastric mucosal prostaglandin in phenylbutazone ulcer rats (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1982, Volume: 79, Issue:3

    Topics: Animals; Gastric Mucosa; Phenylbutazone; Prostaglandins; Rats; Stomach Ulcer

1982
Gastric anti-ulcer activity of (+)-cyanidanol-3, a histidine decarboxylase inhibitor.
    European journal of pharmacology, 1981, Jan-05, Volume: 69, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Benzopyrans; Carboxy-Lyases; Catechin; Female; Gastric Acidity

1981
The effect of pindolol and salmon calcitonin on experimental gastric ulcers in rats.
    Hepato-gastroenterology, 1980, Volume: 27, Issue:2

    Topics: Animals; Calcitonin; Disease Models, Animal; Ligation; Male; Phenylbutazone; Pindolol; Pylorus; Rats

1980
Indomethacin produces gastric antral ulcers in the refed rat.
    Gastroenterology, 1981, Volume: 81, Issue:4

    Topics: Adrenalectomy; Animals; Aspirin; Fasting; Indomethacin; Intestines; Male; Phenylbutazone; Prostaglan

1981
Synergism between acid and gastric contractile activity in the genesis of ulceration and hemorrhage in the phenylbutazone-treated rat.
    Surgery, 1981, Volume: 90, Issue:3

    Topics: Animals; Atropine; Female; Gastric Juice; Gastric Mucosa; Gastrointestinal Motility; Peptic Ulcer He

1981
[Gastrocolonic fistula secondary to a drug-induced ulcer].
    Medecine & chirurgie digestives, 1981, Volume: 10, Issue:7

    Topics: Aged; Colonic Diseases; Female; Gastric Fistula; Humans; Intestinal Fistula; Phenylbutazone; Stomach

1981
Effects of N-acetyl-L-carnosine aluminum (CL-1700) on various acute gastric lesions and gastric secretion in rats.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Carnosine; Dipeptides; Gastric Mucosa; Indomethacin; Male; Phen

1981
A new potent anti-inflammatory quinazolone.
    Pharmacological research communications, 1981, Volume: 13, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Cats; Edema; Female; Heart Rate; Lethal Dose 50;

1981
Vitamin B12 and a lyophilised extract of lamb gastric mucosa in the treatment of two digestive pathological models in the rat and the dog. Clinical and macroscopical observations.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:3

    Topics: Animals; Body Weight; Disease Models, Animal; Dogs; Female; Freeze Drying; Gastrectomy; Gastric Muco

1980
Misuse of veterinary phenylbutazone.
    Archives of internal medicine, 1995, Jun-12, Volume: 155, Issue:11

    Topics: Acute Kidney Injury; Humans; Male; Middle Aged; Phenylbutazone; Self Medication; Stomach Ulcer; Vete

1995
Gastric antiulcer activity of pentacaine: possible mechanism of action.
    Physiological research, 1994, Volume: 43, Issue:3

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Carbamates; Cysteamine; Duodenal Ulcer; Ethanol; F

1994
Aminopyrazinyl derivatives: synthesis and evaluation of antiinflammatory and related activities.
    Farmaco (Societa chimica italiana : 1989), 1994, Volume: 49, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Edema; Femal

1994
Protective action of vinpocetine against experimentally induced gastric damage in rats.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:9

    Topics: Acetates; Acetic Acid; Administration, Oral; Animals; Anti-Ulcer Agents; Dinoprostone; Ethanol; Fema

1993
Gastroprotective effect of stereoisomeric cis- and trans-2-(1-pyrrolidinyl) and 2-(1-pyrrolidinylmethyl)cyclohexyl alkoxycarbanilates in rats.
    Die Pharmazie, 1997, Volume: 52, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carbamates; Central Nervous Sys

1997
Synthesis of some novel pyrazole derivatives as potential antiinflammatory agents with minimum ulcerogenic activity.
    Die Pharmazie, 1998, Volume: 53, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Foot; Gastric Mucosa; Indometh

1998
Anti-inflammatory activity of 2-acyl-5(3)-hydroxytetrahydro-1H-pyrazole derivatives.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Cell Count; Carrageenan; Edema; Epinephrine;

1999
Anti-inflammatory and anti-ulcer activity of Calligonum comosum in rats.
    Fitoterapia, 2001, Volume: 72, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Disease Models, An

2001
[Value of the "gastric chamber", new technic performed ex vivo, for the study of the gastric mucosa of the rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1975, Volume: 169, Issue:3

    Topics: Animals; Drug Evaluation, Preclinical; Gastric Mucosa; Hydrogen-Ion Concentration; Male; Perfusion;

1975
The pharmacology of benoxaprofen (2-[4-chlorophenyl]-alpha-methyl-5-benzoxazole acetic acid), LRCL 3794, a new compound with antiinflammatory activity apparently unrelated to inhibition of prostaglandin synthesis.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Arthritis, Experimental; Benzoxazo

1977
Gastric mucosal injury from common drugs.
    Postgraduate medicine, 1978, Volume: 63, Issue:4

    Topics: Adrenal Cortex Hormones; Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastric Mucosa; G

1978
Activity of a lyophilised whole extract of lamb gastric mucosa in several experimental models of digestive pathology in the rat, the dog and the monkey.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:4

    Topics: Animals; Body Weight; Diarrhea; Dogs; Female; Gastric Mucosa; Gastrointestinal Diseases; Haplorhini;

1977
[Effect of amitriptyline on the ulcerogenic action of phenylbutazone and reserpine with respect to calcium levels in the stomach wall and blood in rats of different ages (author's transl)].
    Bratislavske lekarske listy, 1979, Volume: 71, Issue:2

    Topics: Age Factors; Amitriptyline; Animals; Calcium; Gastric Mucosa; Phenylbutazone; Rats; Reserpine; Stoma

1979
[Influence of nialamide on the ulcerogenic action of phenylbutazone and reserpine in relation to calcium levels in the gastric wall and blood of rats of different age (author's transl)].
    Ceskoslovenska gastroenterologie a vyziva, 1979, Volume: 33, Issue:4

    Topics: Animals; Calcium; Female; Gastric Mucosa; Male; Nialamide; Phenylbutazone; Rats; Reserpine; Stomach

1979
[Influence of season and weather on experimental gastric ulcers in the rat].
    International journal of biometeorology, 1979, Volume: 23, Issue:4

    Topics: Animals; Atmospheric Pressure; Humidity; Phenylbutazone; Rats; Restraint, Physical; Seasons; Stomach

1979
[Irritative activity of a new anti-inflammatory agent 4-(p-chorophenyl)-2-phenyl-5-thiazoleacetic acid (CH-800) on the gastrointestinal tract in rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:8

    Topics: Acetates; Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Digestive Sy

1979
The influence of amitriptylinoxide on experimental ulcers and gastric secretion in rats.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:10b

    Topics: Amitriptyline; Animals; Carbachol; Female; Gastric Mucosa; Humans; Male; Phenylbutazone; Rats; Restr

1978
[The relationship between the levels of calcium on the stomach wall and in the blood and ulcerogenic effect of phenylbutazone and reserpine in intact, adrenalectomized and vagotomized rats of various age (author's transl)].
    Ceskoslovenska gastroenterologie a vyziva, 1978, Volume: 32, Issue:2

    Topics: Adrenalectomy; Age Factors; Animals; Calcium; Disease Models, Animal; Gastric Mucosa; Phenylbutazone

1978
Effects of cold or restraint on incidence of gastric ulceration induced in rats by ulcerogenic drugs.
    European journal of pharmacology, 1978, Sep-01, Volume: 51, Issue:1

    Topics: Animals; Aspirin; Cimetidine; Cold Temperature; Female; Histamine; Indomethacin; Male; Phenylbutazon

1978
[Comparative studies on gastrointestinal damage induced by non-steroidal anti-inflammatory drugs in rats (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1978, Volume: 98, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Flurbiprofen; Indometh

1978
Interactive aggression on gastric ulcer development.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1978, Volume: 19, Issue:3

    Topics: Age Factors; Animals; Cold Temperature; Female; Immobilization; Male; Phenylbutazone; Rats; Stomach

1978
Plasma exchange in severe rhesus disease.
    British medical journal, 1977, Jun-04, Volume: 1, Issue:6074

    Topics: Animals; Apazone; Humans; Oxyphenbutazone; Phenylbutazone; Rats; Stomach Ulcer; Triazines

1977
Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 227, Issue:1

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Edema; Gr

1977
[Effect of vagotomy and lysergic acid diethylamide (LSD) on ulcerogenic action of phenylbutazone and reserpine in rats with regard to the role of 5-hydroxytryptamine (author's transl)].
    Bratislavske lekarske listy, 1977, Volume: 68, Issue:3

    Topics: Animals; Drug Synergism; Female; Gastric Mucosa; Lysergic Acid Diethylamide; Male; Phenylbutazone; R

1977
Anti-ulcer effects of 4'-(2-carboxyetyl) phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride (cetraxate) on various experimental gastric ulcers in rats.
    Japanese journal of pharmacology, 1976, Volume: 26, Issue:4

    Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Cortisone; Cyclohexanecarboxylic Acids; Disease Model

1976
Pharmacological properties of thiazolinobutazone (LAS 11 871). III. General pharmacology, ulcerogenic effects and acute toxicity.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:7

    Topics: Animals; Autonomic Nervous System; Brain; Cats; Diuresis; Female; Hemodynamics; Lethal Dose 50; Male

1976
[Gastric ulcers induced by phenylbutazone in rats. Pathogenetic theory].
    Bollettino della Societa italiana di biologia sperimentale, 1975, Jan-30, Volume: 51, Issue:1-2

    Topics: Animals; Injections, Intraperitoneal; Phenylbutazone; Rats; Stomach Ulcer

1975
[Gastric ulcer induced in the rat by non-steroid anti-inflammatory agents and the synergic effect of exogenous histamine].
    Bollettino chimico farmaceutico, 1975, Volume: 114, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Drug Synergism; Flufenamic Acid; Histamine; Indomethacin

1975
Some pharmacological properties of 2-aryl-1,3-indandione derivatives.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticoagulants; Antitussive Agents; Drug Evaluation,

1975
Drugs and gastric damage.
    Drugs, 1976, Volume: 11, Issue:1

    Topics: Adrenal Cortex Hormones; Aspirin; Buffers; Caffeine; Drug Compounding; Drug-Related Side Effects and

1976
[The part of lysosomal enzymes in drug-induced ulcerogenesis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 111, Issue:4

    Topics: Animals; Aspirin; Cathepsins; Deoxyribonucleases; Indomethacin; Lysosomes; Male; Phenylbutazone; Qui

1991
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoquinones; Capillary

1991
The pharmacological profile of aceclofenac, a new nonsteroidal antiinflammatory and analgesic drug.
    Agents and actions. Supplements, 1991, Volume: 32

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dogs; Female; Indomethacin; Male; Mice

1991
[The effect of proximal selective vagotomy on experimental gastric mucosal lesions in the rat].
    Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR, 1990, Volume: 23, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Gastric Mucosa; Ischemia; Phenylbutazone; Rats; Rats, Inbre

1990
Efficacy of combined ranitidine and pentacaine treatment in experimentally induced gastric damage in rats.
    Agents and actions, 1990, Volume: 30, Issue:1-2

    Topics: Acetates; Acetic Acid; Anesthetics, Local; Animals; Carbamates; Drug Therapy, Combination; Female; P

1990
Chemical and pharmacological investigations on 2H-pyridazino[4,5-b] [1,4]benzothiazin-1(10H)-one derivatives.
    Farmaco (Societa chimica italiana : 1989), 1989, Volume: 44, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Chemical Phenomena;

1989
Sulphasalazine and PhCL28A inhibit the formation of ethanol- and phenylbutazone-induced rat gastric ulcers: lack of involvement of endogenous prostaglandins?
    British journal of pharmacology, 1988, Volume: 93, Issue:3

    Topics: Animals; Azo Compounds; Ethanol; Female; Phenylbutazone; Prostaglandins; Rats; Rats, Inbred Strains;

1988
Horse pill ("bute") hemorrhage.
    Journal of clinical gastroenterology, 1988, Volume: 10, Issue:2

    Topics: Adult; Animals; Gastrointestinal Hemorrhage; Horse Diseases; Horses; Humans; Male; Phenylbutazone; S

1988
Pharmacological activity of FPP028 (2-phenylpyrazolo-4-ethyl-4,7-dihydro [1,5a]pyrimidin-7-one) a new non-steroid anti-inflammatory agent.
    Pharmacological research communications, 1986, Volume: 18, Issue:3

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

1986
Antiulcerogenic activity of zinc acexamate in different experimental models.
    Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:7

    Topics: Aminocaproates; Aminocaproic Acid; Animals; Bile Acids and Salts; Disease Models, Animal; Female; Ma

1987
[The effect of calcium chloride on the ulcerogenic effect of ketophenylbutazone in relation to the calcium content of the gastric wall].
    Bratislavske lekarske listy, 1985, Volume: 84, Issue:6

    Topics: Animals; Calcium; Calcium Chloride; Female; Male; Phenylbutazone; Rats; Rats, Inbred Strains; Stomac

1985
Effect of domperidone on experimentally induced gastric ulcers in rats.
    International journal of tissue reactions, 1986, Volume: 8, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Domperidone; Female; Gastric Mucosa; Male; Phenylbutazone; Rats

1986
Effect of nicotine and caffeine pretreatment on the gastric mucosal damage induced by aspirin, phenylbutazone, and reserpine in rats.
    Toxicology and applied pharmacology, 1985, Jun-30, Volume: 79, Issue:2

    Topics: Administration, Oral; Animals; Aspirin; Caffeine; Drug Synergism; Female; Gastric Mucosa; Male; Nico

1985
Studies on biological activities of melanin from marine animals. III. Inhibitory effect of SM II (low molecular weight melanoprotein from squid) on phenylbutazone-induced ulceration in gastric mucosa in rats, and its mechanism of action.
    Chemical & pharmaceutical bulletin, 1985, Volume: 33, Issue:5

    Topics: Animals; Aspirin; Decapodiformes; Gastric Mucosa; Invertebrate Hormones; Male; Melanins; Phenylbutaz

1985
Effect of nicotine, alcohol and caffeine pretreatment on the gastric mucosal damage induced by aspirin, phenylbutazone and reserpine in rats.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:1

    Topics: Animals; Aspirin; Caffeine; Drug Interactions; Ethanol; Female; Gastric Mucosa; Male; Nicotine; Phen

1985
Studies on the healing of experimental ulcer in the rat II: influence of anti-inflammatory drugs on the healing of the acetic acid ulcer and the components in gastric tissue.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:3

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Body Weight; Cortisone; Gastric Mucosa; Hexosamines; Hy

1974
Pharmacology of zolimidine (2-(p-methylsulfonylphenyl)-imidazo (1,2-a) pyridine) a new non-anticholinergic gastroprotective agent. II) Protective activity against drug-induced experimental ulcers.
    Panminerva medica, 1974, Volume: 16, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Guinea Pigs; Histamine; Histamine H1 Antagon

1974
Pharmacology of zolimidine (2-(p-methylsulfonylphenyl)-imidazo (1,2-a) pyridine) a new non-anticholinergic gastroprotective agent. IV) Enhancement of gastric mucus production in different experimental models.
    Panminerva medica, 1974, Volume: 16, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cold Temperature; Gastric Mucins; Gastric Mu

1974
[Action of castration on the gastric lesions caused by phenylbutazone in the rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1967, Volume: 161, Issue:4

    Topics: Animals; Castration; Female; Gonads; Male; Phenylbutazone; Rats; Stomach Ulcer

1967
[Endogenous histamine and experimental gastric ulcers in the rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1967, Volume: 161, Issue:1

    Topics: Animals; Guanidines; Histamine; Hydroxylamines; Phenylbutazone; Rats; Reserpine; Stomach Ulcer

1967
Environmental factors and the Australian gastric ulcer change.
    The Medical journal of Australia, 1969, Jun-07, Volume: 1, Issue:23

    Topics: Adrenal Cortex Hormones; Adult; Alcohol Drinking; Aspirin; Australia; Disabled Persons; Duodenal Ulc

1969
[Iatrogenic gastroduodenal ulcerations. Corticosteroids excluded].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1973, Nov-20, Volume: 49, Issue:47

    Topics: Aged; Bone Neoplasms; Carcinoma, Squamous Cell; Cyclophosphamide; Duodenal Ulcer; Female; Humans; In

1973
Anti-inflammatory drugs in rheumatic diseases.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin

1974
Evaluation of the potential of gastric ulceration after administration of certain drugs.
    Experimental and molecular pathology, 1967, Volume: 6, Issue:1

    Topics: Amines; Aminopyrine; Animals; Ascorbic Acid; Aspirin; Chlorpromazine; Cortisone; Desoxycorticosteron

1967
Prevention of experimental gastric ulcer in rats by a substance which increases biosynthesis of acid mucopolysaccharides.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:2

    Topics: Animals; Gastric Mucosa; Glycosaminoglycans; Male; Phenylbutazone; Rats; Salicylates; Stomach Ulcer;

1970
Experimental gastric ulcers and uropepsinogen excretion in the rat.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:9

    Topics: Animals; Atropine; Carbon Tetrachloride; Endopeptidases; Enzyme Precursors; Female; Hydrochlorothiaz

1971
Experimental gastric ulcers and stomach tissue pepsin activity in the rat.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:4

    Topics: Animals; Atropine; Gastric Mucosa; Pepsin A; Phenylbutazone; Pyrimidines; Rats; Reserpine; Stomach U

1972
[Effect of guanethidine-induced sympathectomy on the ulcerogenic effect of phenylbutazone in rats of different age].
    Ceskoslovenska gastroenterologie a vyziva, 1974, Volume: 28, Issue:8

    Topics: Age Factors; Animals; Drug Synergism; Female; Guanethidine; Male; Phenylbutazone; Rats; Stomach Ulce

1974
Species differences in susceptibility to the gastro-ulcerogenic action of anti-inflammatory agents.
    Pharmacology, 1974, Volume: 11, Issue:4

    Topics: Administration, Oral; Ambystoma; Animals; Anti-Inflammatory Agents; Cricetinae; Dose-Response Relati

1974
[Treatment of gastric ulcer with acetazolamide and the differentiation between benign and malignant niches].
    Giornale di clinica medica, 1974, Volume: 55, Issue:5

    Topics: Acetazolamide; Diagnosis, Differential; Gastric Juice; Humans; Phenylbutazone; Stomach Neoplasms; St

1974
Gastric mucosal damage by anti-inflammatory drugs.
    Rheumatology and physical medicine, 1972, Volume: 11, Issue:8

    Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diffusion; Gastric Mucins; Gastric Mucosa; Gastritis;

1972
Effects of the non-steroidal antiphlogistics on the gastric mucosal barrier and hexosamine content in rats.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Biological Transport; Carboxylic Acids; Chlorine; Cycloh

1972
[Ulcers of the gastroduodenal tract due to drugs. Apropos of a personal experience].
    Acta gastro-enterologica Belgica, 1972, Volume: 35, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Aged; Analgesics; Aspirin; Duodenal Ulcer; Female; Gastrointestinal

1972
[Gastro-duodenal tolerance of some drugs with analgesic effect. Clinico-endoscopic considerations].
    Minerva medica, 1974, Feb-24, Volume: 65, Issue:14

    Topics: Analgesics; Anti-Inflammatory Agents; Antimalarials; Aspirin; Digestive System; Duodenal Ulcer; Esop

1974
Pharmacology of a new non-steroidal anti-inflammatory agent 7-chloro-3,3a-dihydro-2-methyl-2H,9H-isoxazolo-(3,2-b)(1,3)-benzoxazin-9-one (W-2395).
    European journal of pharmacology, 1974, Volume: 26, Issue:1

    Topics: Adjuvants, Immunologic; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoxazi

1974
Renal and gastric lesions after phenylbutazone and indomethacin in the rat.
    Pathology, 1974, Volume: 6, Issue:4

    Topics: Animals; Ascites; Epithelium; Female; Gastrointestinal Hemorrhage; Indomethacin; Kidney; Kidney Papi

1974
Biological activities of metabolites of 6-chloro-5-cyclohexylindan-1-carboxylic acid (TAI-284: anti-inflammatory agent).
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Dose-Response Relationship, Drug; Edema;

1974
Effects of thiocyanate and acetylsalicylic acid on the gastric mucosal barrier in rats.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:5

    Topics: Administration, Oral; Animals; Aspirin; Biological Transport; Carbonic Anhydrase Inhibitors; Carboni

1972
[Gastric erosions and ulcerations in gastritis caused by drugs].
    Zeitschrift fur Gastroenterologie, 1972, Volume: 10, Issue:8

    Topics: Aminopyrine; Aspirin; Drug-Related Side Effects and Adverse Reactions; Gastritis; Gastroscopy; Gluco

1972
Action of L-dopa, norepinephrine and amantadine on ulcers caused by reserpine in the rat.
    Digestion, 1972, Volume: 7, Issue:5

    Topics: Administration, Oral; Amantadine; Animals; Dihydroxyphenylalanine; Dose-Response Relationship, Drug;

1972
[Experimental gastric ulceration. Rapid method of induction in the rat by combined drug treatment].
    Bollettino chimico farmaceutico, 1973, Volume: 112, Issue:1

    Topics: Aminopyrine; Animals; Aspirin; Drug Combinations; Histamine; ortho-Aminobenzoates; Phenylbutazone; R

1973
Phenylbutazone ulcer and vagotomy in the rat.
    Scandinavian journal of gastroenterology, 1973, Volume: 8, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Male; Phenylbutazone; Rats; Stomach Ulcer; Time Factors;

1973
Vagotomy and healing of phenylbutazone ulcer in the rat.
    Scandinavian journal of gastroenterology, 1973, Volume: 8, Issue:4

    Topics: Animals; Body Weight; Epithelium; Male; Phenylbutazone; Rats; Stomach Ulcer; Time Factors; Vagotomy;

1973
Intragastric pressure, secretagogue characteristics, and pathogenesis of phenylbutazone ulcer.
    Scandinavian journal of gastroenterology, 1973, Volume: 8, Issue:4

    Topics: Animals; Gastric Acidity Determination; Gastric Juice; Hydrogen-Ion Concentration; Ligation; Male; P

1973
[Significance of the gastric mucus as a mucosa-protection].
    Fortschritte der Medizin, 1974, Jan-17, Volume: 92, Issue:2

    Topics: Cortisone; Gastric Juice; Gastric Mucosa; Glycoproteins; Humans; Indomethacin; Phenylbutazone; Stoma

1974
Upper gastrointestinal disease in rheumatoid arthritis.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Arizona; Arthritis, Rheumatoid; Aspir

1974
[Effect of phenylbutazone on the 5-hydroxytryptamine content of the gastric wall in rats of different ages (author's transl)].
    Ceskoslovenska gastroenterologie a vyziva, 1974, Volume: 28, Issue:5

    Topics: Age Factors; Animals; Female; Gastric Mucosa; Male; Phenylbutazone; Rats; Serotonin; Stomach Ulcer

1974
Multiple benign gastric ulcers. A clinical and gastroscopic study.
    The American journal of gastroenterology, 1974, Volume: 62, Issue:1

    Topics: Adult; Aged; Alcohol Drinking; Gastroscopy; Humans; Indomethacin; Male; Middle Aged; Peptic Ulcer He

1974
[Stomach ulcer induced by phenylbutazone and its course in adult rats].
    Bratislavske lekarske listy, 1972, Volume: 57, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Animals; Epinephrine; Metyrapone; Phenylbutazone; Promethazine; Propr

1972
[Stomach ulcer caused by phenylbutazone and its influencing in rats of different age groups].
    Bratislavske lekarske listy, 1972, Volume: 57, Issue:4

    Topics: Age Factors; Animals; Disease Models, Animal; Epinephrine; Phenylbutazone; Promethazine; Rats; Stoma

1972
[Ketazon not more gentle to the stomach than Blutazolidin].
    Medizinische Klinik, 1972, May-12, Volume: 67, Issue:19

    Topics: Humans; Oxyphenbutazone; Phenylbutazone; Stomach Ulcer

1972
Pharmacological investigations of benzothiazoline derivatives.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:4

    Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Benzyl Compounds; Body Temperature; Carrageen

1972
[Measurement of resistance of the gastric muco-protective barrier: a modification of the Shay technic].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:1

    Topics: Animals; Atropine; Female; Gastric Juice; Gastric Mucosa; Ligation; Methods; Neuraminic Acids; Pheny

1971
Glycopeptides from normal and ulcered gastric mucosa of pig.
    Experientia, 1971, Volume: 27, Issue:8

    Topics: Animals; Carbohydrates; Chromatography; Chromatography, Gas; Fucose; Gastric Mucosa; Glycopeptides;

1971
[Gastric ulcers produced by an association of ulcerogenic drugs and restraint].
    Biologie et gastro-enterologie, 1971, Volume: 4

    Topics: Animals; Aspirin; Female; Immobilization; Male; Methylprednisolone; Phenylbutazone; Pyrazoles; Rats;

1971
[Pharmacological study on thiocarboxamides with antisecretory and ulceroprotective properties].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:10

    Topics: Amides; Animals; Autonomic Nervous System; Dogs; Female; Gastric Juice; Gastric Mucosa; Lethal Dose

1971
[Experimental study of the pharmacodynamic effects of a camphosulfonic derivative of nicotinoyl dimethyl pyrazolone].
    Bulletin de l'Academie royale de medecine de Belgique, 1968, Volume: 8, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Body Weight; Eosinophils; Heart; Kidney; Liver; Nicot

1968
Preventing effects of benzyl-tri (beta-propoxyethyl) ammonium iodide (U-247-51) and benzyl-tri (beta-butoxyethyl) ammonium bromide (U-247-73) on the experimental gastric ulcers.
    Acta Scholae Medicinalis Universitatis in Kioto, 1970, Volume: 40, Issue:3

    Topics: Animals; Caffeine; Female; Gastric Juice; Histamine; Male; Norepinephrine; Phenylbutazone; Physostig

1970
[Histological changes of the gastric wall in dogs submitted to the action of phenylbutazone].
    Acta gastro-enterologica Belgica, 1970, Volume: 33, Issue:7

    Topics: Animals; Dogs; Duodenal Ulcer; Gastric Mucosa; Phenylbutazone; Stomach; Stomach Ulcer

1970
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. II. Toxicological and general pharmacological properties.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Autonomic Nervous System; Blood Circulation; Blood Gluco

1970
[Gastroduodenal complications as a result of using corticosteroid and pyrapolydine agents].
    Vestnik khirurgii imeni I. I. Grekova, 1971, Volume: 106, Issue:1

    Topics: Adolescent; Duodenal Ulcer; Glucocorticoids; Humans; Male; Phenylbutazone; Stomach Ulcer

1971
[Metabolic disposition for phenylbutazone in relation to its ulcerogenic effect in rats of different age].
    Ceskoslovenska gastroenterologie a vyziva, 1971, Volume: 25, Issue:2

    Topics: Age Factors; Animals; Phenylbutazone; Rats; Spectrophotometry; Stomach Ulcer; Time Factors

1971
[Influence of bilateral vagotomy on the incidence and cure of phenylbutazone-induced ulcers. Experimental study on rats].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1967, Volume: 49, Issue:1

    Topics: Animals; Male; Phenylbutazone; Rats; Stomach Ulcer; Vagotomy

1967
[The ulcerogenic activity of phenylbutazone in relation to special dietary deficiency. Experimental study on rats].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1967, Volume: 49, Issue:1

    Topics: Animals; Phenylbutazone; Protein Deficiency; Radiation Effects; Rats; Stomach Ulcer; Vitamin A Defic

1967
[Vagotomy in phenylbutazone-induced ulcer. Experimental study on rats].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1967, Volume: 49, Issue:1

    Topics: Animals; Gastric Juice; Gastric Mucosa; Male; Phenylbutazone; Rats; Secretory Rate; Stomach Ulcer; V

1967
Toxicological investigation of alpha-isopropyl-alpha-(2-dimethylaminoethyl)-1-naphthylacetamide (Naphthypramide, DA 992): a new anti-inflammatory agent.
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:11

    Topics: Abnormalities, Drug-Induced; Amides; Animals; Anti-Inflammatory Agents; Blood Proteins; Body Weight;

1967
Phenylbutazone and histamine formation in rat glandular stomach: its relationship to gastric ulceration.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:1

    Topics: Adrenalectomy; Animals; Fasting; Female; Gastric Mucosa; Histamine; Hypophysectomy; Phenylbutazone;

1968
[Gast roduodenal complications of steroid and phenylbutazone therapy from the surgical viewpoint].
    Zentralblatt fur Chirurgie, 1968, Jul-06, Volume: 93, Issue:27

    Topics: Adolescent; Adult; Aged; Dexamethasone; Duodenal Ulcer; Female; Gastritis; Germany, East; Glucocorti

1968
[Pharmacological and toxicological testing of new anti-inflammatory agent azapropazon=3-dimethylamine-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bloo

1969
[Phenylbutazone gastric ulcer in the female rat. Action of a sulfated polysaccharide, colloidal aluminum hydroxide and sodium bicarbonate].
    Prensa medica argentina, 1965, Jun-25, Volume: 52, Issue:22

    Topics: Animals; Antacids; Female; Phenylbutazone; Rats; Stomach Ulcer

1965
[Concerning the ulcerogenic action of phenylbutazone. Effect on it of carbonic anhydrase inhibiting substances].
    Studii si cercetari de fiziologie, 1965, Volume: 10, Issue:4

    Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Phenylbutazone; Rats; Stomach Ulcer

1965
[Contribution to the pharmacodynamic study of 1,2-diphenyl-3,5-dioxo-4-n-butyl-pyrazolidinopiperazine].
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 160, Issue:2

    Topics: Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Blood Pressure; Diuresis; Dogs; Edema; G

1966
[Medicinal ulcers of the greater gastric curvature. Thoughts apropos of 2 cases].
    Revue medicale de Liege, 1966, Aug-15, Volume: 21, Issue:16

    Topics: Aged; Aspirin; Humans; Male; Middle Aged; Phenylbutazone; Sodium Salicylate; Stomach Ulcer; Triamcin

1966
[The role of gastric secretion in the genesis of ulcers caused by phenylbutazone].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1966, Volume: 47, Issue:3

    Topics: Animals; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Male; Phenylbutazone; Rats; S

1966
[The importance of the diet in the genesis of phenylbutazone ulcers in rats].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1966, Volume: 47, Issue:3

    Topics: Animals; Diet; Male; Phenylbutazone; Rats; Stomach Ulcer

1966
[Influence of partial hepatectomy on the ulcerogenic power of phenylbutazone in rats].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1966, Volume: 47, Issue:3

    Topics: Animals; Hepatectomy; Male; Phenylbutazone; Rats; Stomach Ulcer

1966
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