pd 98059 and Vasospasm, Intracranial
pd 98059 has been researched along with Vasospasm, Intracranial in 5 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Vasospasm, Intracranial: Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Using a "two-hemorrhage" model of subarachnoid hemorrhage (SAH), this study investigated the function of ERK1/2 and vascular wall cell proliferation in pathological development of cerebral vasospasm." | 1.35 | Role of ERK1/2 and vascular cell proliferation in cerebral vasospasm after experimental subarachnoid hemorrhage. ( Chen, D; Chen, JJ; Guan, JH; Liu, YH; Yin, Q, 2009) |
"Even though cerebral vasospasm after subarachnoid hemorrhage (SAH) causes cerebral ischemia or infarction, the metabolic alterations in cerebrospinal fluids (CSF) after SAH have not been studied." | 1.31 | Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs. ( Aoki, K; Badr, A; Tibbs, R; Yin, W; Zhang, J, 2002) |
Research
Studies (5)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Chen, D | 1 |
Chen, JJ | 1 |
Yin, Q | 1 |
Guan, JH | 1 |
Liu, YH | 1 |
Yin, W | 1 |
Tibbs, R | 2 |
Aoki, K | 4 |
Badr, A | 2 |
Zhang, J | 2 |
Zubkov, A | 1 |
Meguro, T | 1 |
Parent, A | 1 |
Zubkov, AY | 2 |
Tibbs, RE | 2 |
Zhang, JH | 2 |
Other Studies
5 other studies available for pd 98059 and Vasospasm, Intracranial
Article | Year |
---|---|
Role of ERK1/2 and vascular cell proliferation in cerebral vasospasm after experimental subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Cell Proliferation; Disease Models, Animal; Enzyme Activation; Enzyme Inhib | 2009 |
Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs.
Topics: Analysis of Variance; Animals; Caspase Inhibitors; Cerebral Hemorrhage; Disease Models, Animal; Dogs | 2002 |
Effects of mitogen-activated protein kinase inhibitors on cerebral vasospasm in a double-hemorrhage model in dogs.
Topics: Animals; Butadienes; Cerebral Angiography; Cerebral Arteries; Disease Models, Animal; Dogs; Flavonoi | 2000 |
Prevention of vasospasm in penetrating arteries with MAPK inhibitors in dog double-hemorrhage model.
Topics: Animals; Basilar Artery; Butadienes; Cerebral Arteries; Dogs; Enzyme Inhibitors; Female; Flavonoids; | 2000 |
Role of MAPK in chronic cerebral vasospasm.
Topics: Animals; Blood Pressure; Chronic Disease; Dimethyl Sulfoxide; Dogs; Female; Flavonoids; Male; Mitoge | 2002 |