pd 98059 has been researched along with Colitis in 3 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the association of interleukin-12 (IL-12) with development of dextran sulfate sodium (DSS)-induced colitis in mice, and examined the effects of TJN-419, a synthetic compound derived from acteoside, on this process." | 3.76 | TJN-419 improves dextran sulfate sodium-induced colitis via inhibition of interleukin-12 release. ( Hasegawa, Y; Hattori, T; Inagaki, Y; Koseki, J; Maruyama, H; Sadakane, C; Shindo, S; Takeda, H; Takeda, S, 2010) |
| "Experimental colitis has been shown to trigger bladder hyperactivity and hyperalgesia in rats." | 1.72 | Inhibition of CXCR4 in Spinal Cord and DRG with AMD3100 Attenuates Colon-Bladder Cross-Organ Sensitization. ( Dong, X; Li, L; Lu, Q; Xu, J; Yang, Z; Yi, S; Zhang, H; Zhao, J; Zhu, J, 2022) |
| "Colitis was induced by dextran sulfate sodium in mice, together with HGF gene transfer by EP." | 1.34 | Hepatocyte growth factor promotes colonic epithelial regeneration via Akt signaling. ( Kanayama, M; Kawai, K; Kudo, H; Kudo, T; Nonome, K; Shinno, E; Sugiyama, T; Tabuchi, Y; Takahara, T; Watanabe, A; Xue, F; Yata, Y, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, H | 1 |
| Dong, X | 1 |
| Yang, Z | 1 |
| Zhao, J | 1 |
| Lu, Q | 1 |
| Zhu, J | 1 |
| Li, L | 1 |
| Yi, S | 1 |
| Xu, J | 1 |
| Sadakane, C | 1 |
| Koseki, J | 1 |
| Inagaki, Y | 1 |
| Hasegawa, Y | 1 |
| Shindo, S | 1 |
| Maruyama, H | 1 |
| Takeda, S | 1 |
| Takeda, H | 1 |
| Hattori, T | 1 |
| Kanayama, M | 1 |
| Takahara, T | 1 |
| Yata, Y | 1 |
| Xue, F | 1 |
| Shinno, E | 1 |
| Nonome, K | 1 |
| Kudo, H | 1 |
| Kawai, K | 1 |
| Kudo, T | 1 |
| Tabuchi, Y | 1 |
| Watanabe, A | 1 |
| Sugiyama, T | 1 |
3 other studies available for pd 98059 and Colitis
| Article | Year |
|---|---|
Inhibition of CXCR4 in Spinal Cord and DRG with AMD3100 Attenuates Colon-Bladder Cross-Organ Sensitization.
Topics: Animals; Benzylamines; Colitis; Cyclams; Disease Models, Animal; Extracellular Signal-Regulated MAP | 2022 |
TJN-419 improves dextran sulfate sodium-induced colitis via inhibition of interleukin-12 release.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Antibodies, Neutralizing; Cinnamates; Colitis; Dextran | 2010 |
Hepatocyte growth factor promotes colonic epithelial regeneration via Akt signaling.
Topics: Animals; Cell Line; Cell Proliferation; Chromones; Colitis; Dextran Sulfate; Electroporation; Female | 2007 |