orotic acid and Gout
orotic acid has been researched along with Gout in 34 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The method was used to measure orotic acid and orotidine in urine samples from newborns, healthy controls and patients with gout or deficiency of hypoxanthine-guanine phosphoribosyltransferase receiving allopurinol." | 3.66 | The urinary excretion of orotic acid and orotidine, measured by an isotope dilution assay. ( Schretlen, ED; Tax, WJ; Veerkamp, JH, 1978) |
Research
Studies (34)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (97.06) | 18.7374 |
| 1990's | 1 (2.94) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| WEISSMAN, S | 1 |
| EISEN, AZ | 1 |
| KARON, M | 1 |
| FRANCOMANERA, R | 1 |
| DELBARRE, F | 4 |
| AUSCHER, C | 2 |
| MALAWISTA, SE | 1 |
| SEEGMILLER, JE | 2 |
| Glader, BE | 1 |
| Sullivan, DW | 1 |
| Tax, WJ | 1 |
| Veerkamp, JH | 1 |
| Schretlen, ED | 1 |
| Mert, N | 1 |
| Siniachenko, OV | 1 |
| Diadyk, AI | 1 |
| Oberemchenko, IaV | 1 |
| Vasilenko, IV | 1 |
| Nikolenko, IuI | 1 |
| Fox, IH | 2 |
| Kelley, WN | 7 |
| Cottin, S | 1 |
| Prost, A | 1 |
| Naff, GB | 1 |
| Byers, PH | 1 |
| Becker, MA | 1 |
| de Gery, A | 2 |
| Beardmore, TD | 4 |
| Hatfield, PJ | 1 |
| Simmonds, HA | 1 |
| Cameron, JS | 1 |
| Jones, AS | 1 |
| Cadenhead, A | 1 |
| Arakawa, T | 1 |
| Wada, Y | 2 |
| Wyngaarden, JB | 2 |
| Radi, I | 1 |
| Moreau, RC | 1 |
| Cashman, JS | 1 |
| Louyot, P | 1 |
| Pourel, J | 1 |
| Gaucher, A | 1 |
| Montet, Y | 1 |
| Caraceni, C | 1 |
| Marugo, M | 1 |
| Scopinaro, N | 1 |
| Minuto, F | 1 |
| Carrasco Carrasco, J | 1 |
| Del Regno, F | 1 |
| Capobianco, G | 1 |
| Ryckewaert, A | 1 |
| Dry, J | 1 |
| Paolaggi, F | 1 |
| Saporta, L | 1 |
| Panahi, F | 1 |
| Recordier, AM | 1 |
| Spanio, L | 1 |
| De Battisti, C | 1 |
Reviews
9 reviews available for orotic acid and Gout
| Article | Year |
|---|---|
[DISEASES OF THE METABOLISM OF PURINES AND PYRIMIDINES].
Topics: Gout; Humans; Metabolic Diseases; Orotic Acid; Purines; Pyrimidines; Uric Acid; Urine; Xanthines | 1963 |
The red blood cell as a biopsy tool.
Topics: Biopsy; Carbohydrate Metabolism, Inborn Errors; Erythrocytes; Galactosemias; Gout; Humans; Immunolog | 1981 |
Phosphoribosylpyrophosphate in man: biochemical and clinical significance.
Topics: Adenine; Adrenocorticotropic Hormone; Allopurinol; Animals; Glycogen; Gout; Humans; Lesch-Nyhan Synd | 1971 |
Genetic aspects of gout.
Topics: Adenine; Allopurinol; Carbon Radioisotopes; Erythrocytes; Fibroblasts; Glucosephosphate Dehydrogenas | 1974 |
[Inborn errors of purine and pyrimidine metabolism].
Topics: Gout; Humans; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Transferases; Uracil; Xanthi | 1967 |
Gout.
Topics: Allopurinol; Arthritis; Carbon Isotopes; Colchicine; Glutamine; Gout; Humans; Kidney; Orotic Acid; P | 1965 |
[Treatment of congenital purine-pyrimidine metabolism anomalies].
Topics: Athetosis; Chorea; Compulsive Behavior; Gout; Humans; Intellectual Disability; Orotic Acid; Purine-P | 1971 |
[Gout].
Topics: Allopurinol; Chondrocalcinosis; Colchicine; Diagnosis, Differential; Diet Therapy; Gout; Humans; Ino | 1970 |
Drug treatment of gout.
Topics: Acute Disease; Allopurinol; Arthritis; Colchicine; Gout; Humans; Orotic Acid; Probenecid; Structure- | 1971 |
Other Studies
25 other studies available for orotic acid and Gout
| Article | Year |
|---|---|
Pseudouridine metabolism. II. Urinary excretion in gout, psoriasis, leukemia, and heterozygous oroticaciduria.
Topics: Gout; Humans; Leukemia; Nucleosides; Nucleotides; Orotate Phosphoribosyltransferase; Orotic Acid; Or | 1962 |
[TREATMENT OF GOUT WITH URACIL-6-CARBOXYLIC ACID AND ITS DERIVATIVES].
Topics: Blood; Body Fluids; Carboxylic Acids; Gout; Humans; Orotic Acid; Pharmacology; Toxicology; Uracil; U | 1963 |
NEW PROSPECTS IN THE TREATMENT OF GOUTY DYSPURINIA.
Topics: Azaserine; Blood; Drug Therapy; Enzyme Inhibitors; Gout; Leucine; Metabolism; Orotic Acid; Oxidoredu | 1964 |
THE EFFECT OF PRETREATMENT WITH COLCHICINE ON THE INFLAMMATORY RESPONSE TO MICROCRYSTALLINE URATE: A MODEL FOR GOUTY INFLAMMATION.
Topics: Biomedical Research; Blood Chemical Analysis; Colchicine; Dosage Forms; Drug Therapy; Gout; Humans; | 1965 |
The urinary excretion of orotic acid and orotidine, measured by an isotope dilution assay.
Topics: Adolescent; Adult; Aging; Allopurinol; Breast Feeding; Child; Female; Gout; Humans; Hypoxanthine Pho | 1978 |
A biochemical investigation on chicken gout observed in the Marmara region in Turkey.
Topics: Animals; Bicarbonates; Blood Proteins; Calcium; Chickens; Gout; Orotic Acid; Poultry Diseases; Refer | 1991 |
[Dispensarization of patients with podagra and renal lesions].
Topics: Adult; Aged; Allopurinol; Ambulatory Care; Cyclophosphamide; Drug Therapy, Combination; Female; Glom | 1985 |
[Uricoeliminating or urico-inhibiting agents? Reasons for a choice].
Topics: Allopurinol; Colchicine; Diet Therapy; Glomerular Filtration Rate; Gout; Humans; Long-Term Care; Oro | 1972 |
Complement as a mediator of inflammation in acute gouty arthritis. I. Studies on the reaction between human serum complement and sodium urate crystals.
Topics: Animals; Calcium; Complement System Proteins; Diphosphates; Erythrocytes; Factor XII; Gout; Hemolysi | 1973 |
Observations of altered intracellular phosphoribosylpyrophosphate (PP-ribose-P) in human disease.
Topics: Adenine; Carbon Radioisotopes; Erythrocytes; Fibroblasts; Formates; Gout; Guanine Nucleotides; Heter | 1974 |
[Molecular bases of the treatment of Lesch-Nyhan syndrome, related syndromes and common gout].
Topics: Adenine Nucleotides; Allopurinol; Feedback; Gout; Guanosine; Humans; Hypoxanthines; Lesch-Nyhan Synd | 1972 |
Effects of allopurinol and oxipurinol on pyrimidine biosynthesis in man.
Topics: Allopurinol; Carbon Dioxide; Carbon Radioisotopes; Carboxy-Lyases; Child; DNA; Erythrocytes; Gout; H | 1974 |
Effects of allopurinol and oxonic acid on pyrimidine metabolism in the pig.
Topics: Allantoin; Allopurinol; Animals; Gout; Guanine; Humans; Orotic Acid; Purine Nucleosides; Species Spe | 1974 |
[Some aspects of enzyme inhibition in therapeutics].
Topics: Allopurinol; Enzyme Inhibitors; Enzymes; Fibrinolysis; Gout; Humans; Orotic Acid | 1970 |
Mechanism of allopurinol-mediated increase in enzyme activity in man.
Topics: Allopurinol; Analysis of Variance; Carbon Isotopes; Carboxy-Lyases; Depression, Chemical; Drug Toler | 1972 |
Mechanism of allopurinol-mediated inhibition of pyrimidine biosynthesis.
Topics: Allopurinol; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromatography, Paper; Depression, Che | 1971 |
[Physiopathology and treatment of hyperuricemia and gout].
Topics: Acidosis; Acute Disease; Gout; Humans; Kidney Failure, Chronic; Orotic Acid; Purines; Urate Oxidase; | 1971 |
[Orotic acid and hyperuricemia caused by fructose].
Topics: Adult; Female; Fructose; Gout; Humans; Male; Orotic Acid; Uric Acid | 1969 |
Allopurinol: alteration in pyrimidine metabolism in man.
Topics: Allopurinol; Carboxy-Lyases; Depression, Chemical; Erythrocytes; Gout; Humans; Hypoxanthines; Kineti | 1970 |
[Association of a uricosuric and a uric acid inhibitor in the prophylaxis and treatment of the basis of gout].
Topics: Female; Gout; Humans; Male; Orotic Acid; Probenecid | 1970 |
[Further studies on the use of orotic acid in the treatment of gout].
Topics: Gout; Humans; Orotic Acid; Uric Acid | 1970 |
[Hyperuricemia. IX. Complications of hyperuricemia. On the treatment of hyperuricemia].
Topics: Allopurinol; Gout; Humans; Joint Diseases; Kidney Calculi; Orotic Acid; Time Factors; Uric Acid; Uri | 1967 |
[Modern therapy of gout].
Topics: Allopurinol; Benzofurans; Colchicine; Diet Therapy; Gout; Humans; Orotic Acid; Urate Oxidase; Uricos | 1968 |
[Practical problems in gout].
Topics: Adrenal Cortex Hormones; Catalase; Colchicine; Diet Therapy; Gout; Humans; Liver Extracts; Orotic Ac | 1965 |
[Experiences with potassium orotate in hyperuricemic subjects].
Topics: Adult; Aged; Blood; Gout; Humans; Middle Aged; Orotic Acid; Potassium; Uric Acid; Urine | 1965 |