Page last updated: 2024-11-01

ofloxacin and Pain

ofloxacin has been researched along with Pain in 13 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"This multinational, multicentre, prospective, randomised, double blind, parallel group, non-inferiority study compared the efficacy and safety of moxifloxacin monotherapy with ofloxacin plus metronidazole in women with uncomplicated pelvic inflammatory disease."9.12Moxifloxacin versus ofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: results of a multicentre, double blind, randomised trial. ( Alefelder, M; Arvis, P; Cronjé, HS; Kureishi, A; Paszkowski, T; Rakoczi, I; Reimnitz, P; Ross, JD; Vildaite, D, 2006)
"This study compared the efficacy, safety, and ear-pain resolution of once-daily ofloxacin otic solution (0."9.12Once-daily ofloxacin otic solution versus neomycin sulfate/polymyxin B sulfate/hydrocortisone otic suspension four times a day: a multicenter, randomized, evaluator-blinded trial to compare the efficacy, safety, and pain relief in pediatric patients with ( Schwartz, RH, 2006)
"This multinational, multicentre, prospective, randomised, double blind, parallel group, non-inferiority study compared the efficacy and safety of moxifloxacin monotherapy with ofloxacin plus metronidazole in women with uncomplicated pelvic inflammatory disease."5.12Moxifloxacin versus ofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: results of a multicentre, double blind, randomised trial. ( Alefelder, M; Arvis, P; Cronjé, HS; Kureishi, A; Paszkowski, T; Rakoczi, I; Reimnitz, P; Ross, JD; Vildaite, D, 2006)
"This study compared the efficacy, safety, and ear-pain resolution of once-daily ofloxacin otic solution (0."5.12Once-daily ofloxacin otic solution versus neomycin sulfate/polymyxin B sulfate/hydrocortisone otic suspension four times a day: a multicenter, randomized, evaluator-blinded trial to compare the efficacy, safety, and pain relief in pediatric patients with ( Schwartz, RH, 2006)
" A dosage of 750 mg q."1.34Safety of prolonged high-dose levofloxacin therapy for bone infections. ( Beltrand, E; Caillaux, M; Dehecq, C; Legout, L; Loïez, C; Migaud, H; Mouton, Y; Poissy, J; Senneville, E; Valette, M; Yazdanpanah, Y, 2007)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's7 (53.85)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Küçükgüzel, SG1
Küçükgüzel, I1
Tatar, E1
Rollas, S1
Sahin, F1
Güllüce, M1
De Clercq, E1
Kabasakal, L1
Huruba, M1
Farcas, A1
Leucuta, DC1
Bucsa, C1
Sipos, M1
Mogosan, C1
Woods, JL1
Scurlock, AM1
Hensel, DJ1
Panas, M1
Karadima, G1
Kalfakis, N1
Vassilopoulos, D1
Schuette, W1
Nagel, S1
von Weikersthal, LF1
Pabst, S1
Schumann, C1
Deuss, B1
Salm, T1
Roscher, K1
Dickgreber, N1
Onoe, H1
Yotsu, RR1
Nakanaga, K1
Hoshino, Y1
Ishii, N1
Takeuchi, T1
Ross, JD1
Cronjé, HS1
Paszkowski, T1
Rakoczi, I1
Vildaite, D1
Kureishi, A1
Alefelder, M1
Arvis, P1
Reimnitz, P1
Schwartz, RH1
Senneville, E1
Poissy, J1
Legout, L1
Dehecq, C1
Loïez, C1
Valette, M1
Beltrand, E1
Caillaux, M1
Mouton, Y1
Migaud, H1
Yazdanpanah, Y1
Listernick, R1
Hennenfent, BR1
Feliciano, AE1
Nuño Mateo, FJ1
Noval Menéndez, J1
Suárez, M1
Guinea, O1
Roberts, C1

Trials

4 trials available for ofloxacin and Pain

ArticleYear
Randomized phase III trial of docetaxel plus carboplatin with or without levofloxacin prophylaxis in elderly patients with advanced non-small cell lung cancer: the APRONTA trial.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2011, Volume: 6, Issue:12

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combined Chem

2011
Moxifloxacin versus ofloxacin plus metronidazole in uncomplicated pelvic inflammatory disease: results of a multicentre, double blind, randomised trial.
    Sexually transmitted infections, 2006, Volume: 82, Issue:6

    Topics: Administration, Oral; Adult; Anti-Infective Agents; Aza Compounds; Double-Blind Method; Drug Therapy

2006
Once-daily ofloxacin otic solution versus neomycin sulfate/polymyxin B sulfate/hydrocortisone otic suspension four times a day: a multicenter, randomized, evaluator-blinded trial to compare the efficacy, safety, and pain relief in pediatric patients with
    Current medical research and opinion, 2006, Volume: 22, Issue:9

    Topics: Administration, Topical; Anti-Bacterial Agents; Child; Child, Preschool; Double-Blind Method; Drug A

2006
Comparison of the ocular comfort of ofloxacin 0.3% ophthalmic solution and lubricant eye drops.
    Clinical pediatrics, 2002, Volume: 41, Issue:3

    Topics: Adult; Anti-Infective Agents; Eye; Eye Diseases; Female; Humans; Lubrication; Male; Ofloxacin; Ophth

2002

Other Studies

9 other studies available for ofloxacin and Pain

ArticleYear
Synthesis of some novel heterocyclic compounds derived from diflunisal hydrazide as potential anti-infective and anti-inflammatory agents.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:7

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Diflunisal; Femal

2007
A VigiBase descriptive study of fluoroquinolone induced disabling and potentially permanent musculoskeletal and connective tissue disorders.
    Scientific reports, 2021, 07-13, Volume: 11, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Adverse Drug Reaction Reporting Systems; Arthralgia; Cip

2021
Pelvic inflammatory disease in the adolescent: understanding diagnosis and treatment as a health care provider.
    Pediatric emergency care, 2013, Volume: 29, Issue:6

    Topics: Adolescent; Anti-Bacterial Agents; Arkansas; Ceftriaxone; Centers for Disease Control and Prevention

2013
Hereditary neuropathy unmasked by levofloxacin.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:10

    Topics: Anti-Bacterial Agents; Charcot-Marie-Tooth Disease; Diagnosis, Differential; Family Health; Humans;

2011
Buruli ulcer accompanied by pain in a Japanese patient.
    The Journal of dermatology, 2012, Volume: 39, Issue:10

    Topics: Anti-Bacterial Agents; Asian People; Buruli Ulcer; Clarithromycin; Drug Therapy, Combination; Face;

2012
Safety of prolonged high-dose levofloxacin therapy for bone infections.
    Journal of chemotherapy (Florence, Italy), 2007, Volume: 19, Issue:6

    Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluati

2007
A 5-year-old girl with headache and eye pain.
    Pediatric annals, 2008, Volume: 37, Issue:1

    Topics: Abducens Nerve Diseases; Anti-Bacterial Agents; Child, Preschool; Cranial Sinuses; Diagnosis, Differ

2008
Changes in white blood cell counts in men undergoing thrice-weekly prostatic massage, microbial diagnosis and antimicrobial therapy for genitourinary complaints.
    British journal of urology, 1998, Volume: 81, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Antibiotics, Antineoplastic; Bacterial Infections; Drug

1998
[Achilles pain and functional impotence in a patient with chronic obstructive pulmonary disease with pneumonia. Tendon rupture caused by levofloxacin].
    Revista clinica espanola, 2001, Volume: 201, Issue:9

    Topics: Achilles Tendon; Aged; Anti-Infective Agents; Humans; Levofloxacin; Male; Ofloxacin; Pain; Pneumonia

2001