Page last updated: 2024-11-01

ofloxacin and Myopia

ofloxacin has been researched along with Myopia in 5 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
"The ciprofloxacin eyes were significantly more prone to impaired or delayed wound healing and to the development of corneal haze."2.69Epithelial healing rates with topical ciprofloxacin, ofloxacin, and ofloxacin with artificial tears after photorefractive keratectomy. ( Chuang, AZ; Kiang, E; Mitra, S; Patel, GM; Ramesh, N; Yee, RW, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gris, O1
Güell, JL1
Wolley-Dod, C1
Adán, A1
Lang, J1
Rah, MJ1
Patel, GM1
Chuang, AZ1
Kiang, E1
Ramesh, N1
Mitra, S1
Yee, RW1
Hutchinson, K1
Apel, A1
Yu, EY1
Rao, SK1
Cheng, AC1
Law, RW1
Leung, AT1
Lam, DS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Clinical Trial Comparing the Effect of Moxifloxacin Versus Gatifloxacin Following Pterygium Excision on Corneal Epithelial Healing and Epithelial Toxicity.[NCT00892918]40 participants (Anticipated)Interventional2009-06-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ofloxacin and Myopia

ArticleYear
Epithelial healing rates with topical ciprofloxacin, ofloxacin, and ofloxacin with artificial tears after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2000, Volume: 26, Issue:5

    Topics: Administration, Topical; Adult; Anti-Infective Agents; Ciprofloxacin; Corneal Topography; Drug Thera

2000

Other Studies

4 other studies available for ofloxacin and Myopia

ArticleYear
Diffuse lamellar keratitis and corneal edema associated with viral keratoconjunctivitis 2 years after laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:6

    Topics: Adenovirus Infections, Human; Anti-Infective Agents; Astigmatism; Conjunctivitis, Viral; Corneal Ede

2004
Adverse corneal events associated with corneal reshaping: a case series.
    Eye & contact lens, 2004, Volume: 30, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Child; Contact Lenses; Corneal Ulcer; Eye Infections, Bacterial; Femal

2004
Infectious keratitis in orthokeratology.
    Clinical & experimental ophthalmology, 2002, Volume: 30, Issue:1

    Topics: Acanthamoeba Keratitis; Adult; Antiprotozoal Agents; Astigmatism; Benzamidines; Chloramphenicol; Con

2002
Bilateral peripheral corneal infiltrates after simultaneous myopic laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:5

    Topics: Administration, Topical; Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Corneal Diseases; C

2002