ns 1619 and Cough
ns 1619 has been researched along with Cough in 2 studies
NS 1619: structure given in first source
NS 1619 : A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It is an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study we investigated whether openers of potassium channels, K+ATP--pinacidil and BK+Ca--NS1619, modulate cough reflex and airway smooth muscle (ASM) reactivity in in vivo and in vitro conditions in guinea pigs." | 3.74 | The role of potassium ion channels in cough and other reflexes of the airways. ( Franova, S; Nosalova, G; Sutovska, M, 2007) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Sutovska, M | 1 |
| Nosalova, G | 1 |
| Franova, S | 1 |
| Fox, AJ | 1 |
| Barnes, PJ | 1 |
| Venkatesan, P | 1 |
| Belvisi, MG | 1 |
Other Studies
2 other studies available for ns 1619 and Cough
| Article | Year |
|---|---|
The role of potassium ion channels in cough and other reflexes of the airways.
Topics: Acetylcholine; Aerosols; Airway Resistance; Animals; Benzimidazoles; Citric Acid; Cough; Glyburide; | 2007 |
Activation of large conductance potassium channels inhibits the afferent and efferent function of airway sensory nerves in the guinea pig.
Topics: Afferent Pathways; Animals; Benzimidazoles; Bradykinin; Bronchi; Bronchial Provocation Tests; Citric | 1997 |