norketamine has been researched along with Pain in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Can, AT; Dutton, M; Hermens, DF; Lagopoulos, J | 1 |
| Jokinen, V; Kalso, EA; Lilius, TO; Neuvonen, MS; Niemi, M; Rauhala, PV | 1 |
| Hagelberg, NM; Olkkola, KT; Peltoniemi, MA; Saari, TI | 1 |
| Crooks, PA; Holtman, JR; Johnson-Hardy, J; Wala, EP | 1 |
| Crooks, PA; Hojomat, M; Holtman, JR; Johnson-Hardy, JK; Kleven, M; Wala, EP | 1 |
| Andersen, OK; Arendt-Nielsen, L; Bergadano, A; Spadavecchia, C; Theurillat, R; Thormann, W | 1 |
| Apley, MD; Coetzee, JF; Gehring, R; Tarus-Sang, J | 1 |
| Azad, SC; Beyer, A; Huge, V; Lauchart, M; Magerl, W; Schelling, G; Thieme, D | 1 |
| Bauer, M; Dahan, A; Kest, B; Mooren, R; Olofsen, E; Sarton, E; Sigtermans, M | 1 |
| Anderson, BJ; Brunette, KE; Herd, DW; Schulein, S; Thomas, J; Wiesner, L | 1 |
| Aarts, L; Dahan, A; Morariu, A; Niesters, M; Swartjes, M | 1 |
| Aarts, L; Dahan, A; Khalili-Mahani, N; Martini, C; Niesters, M; Rombouts, S; van Buchem, MA; van Gerven, J | 1 |
| Bushnell, TG; Craig, J | 1 |
| Elliott, KJ; Gorman, AL; Inturrisi, CE; Shimoyama, M; Shimoyama, N | 1 |
2 review(s) available for norketamine and Pain
| Article | Year |
|---|---|
Oral ketamine may offer a solution to the ketamine conundrum.
Topics: Antidepressive Agents; Biological Availability; Humans; Ketamine; Pain | 2023 |
Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy.
Topics: Analgesics; Anesthesia; Animals; Biological Availability; Central Nervous System; Child; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Administration Routes; Humans; Ketamine; Pain; Receptors, N-Methyl-D-Aspartate | 2016 |
2 trial(s) available for norketamine and Pain
| Article | Year |
|---|---|
Effects of low-dose intranasal (S)-ketamine in patients with neuropathic pain.
Topics: Administration, Intranasal; Adult; Aged; Algorithms; Anesthetics, Dissociative; Cardiovascular System; Female; Hemodynamics; Humans; Ketamine; Male; Middle Aged; Pain; Pain Measurement; Peripheral Nervous System Diseases; Stereoisomerism | 2010 |
Effect of subanesthetic ketamine on intrinsic functional brain connectivity: a placebo-controlled functional magnetic resonance imaging study in healthy male volunteers.
Topics: Adult; Anesthetics, Dissociative; Brain; Data Interpretation, Statistical; Hallucinogens; Hot Temperature; Humans; Image Processing, Computer-Assisted; Injections, Intravenous; Ketamine; Linear Models; Magnetic Resonance Imaging; Male; Nerve Net; Pain; Pain Measurement; Single-Blind Method; Young Adult | 2012 |
10 other study(ies) available for norketamine and Pain
| Article | Year |
|---|---|
Ketamine coadministration attenuates morphine tolerance and leads to increased brain concentrations of both drugs in the rat.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Drug Tolerance; Injections, Subcutaneous; Ketamine; Liver; Morphine; Morphine Derivatives; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2015 |
Interaction between morphine and norketamine enantiomers in rodent models of nociception.
Topics: Analgesics, Opioid; Animals; Constriction, Pathologic; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Formaldehyde; Ketamine; Male; Morphine; Motor Activity; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time; Stereoisomerism | 2008 |
Effects of norketamine enantiomers in rodent models of persistent pain.
Topics: Animals; Behavior, Animal; Chronic Disease; Constriction, Pathologic; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Formaldehyde; Hot Temperature; Hyperalgesia; Ketamine; Male; Motor Activity; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Stereotyped Behavior | 2008 |
Plasma levels of a low-dose constant-rate-infusion of ketamine and its effect on single and repeated nociceptive stimuli in conscious dogs.
Topics: Anesthetics, Dissociative; Animals; Dogs; Dose-Response Relationship, Drug; Electromyography; Infusions, Intravenous; Ketamine; Male; Nociceptors; Pain; Prospective Studies; Stereoisomerism; Transcutaneous Electric Nerve Stimulation | 2009 |
Pharmacokinetics of ketamine and its metabolite norketamine administered at a sub-anesthetic dose together with xylazine to calves prior to castration.
Topics: Adrenergic alpha-Agonists; Anesthesia, Intravenous; Anesthetics, Dissociative; Animals; Cattle; Chromatography, Liquid; Drug Combinations; Ketamine; Male; Orchiectomy; Pain; Xylazine | 2009 |
S(+)-ketamine effect on experimental pain and cardiac output: a population pharmacokinetic-pharmacodynamic modeling study in healthy volunteers.
Topics: Adolescent; Adult; Algorithms; Anesthetics, Dissociative; Cardiac Output; Dose-Response Relationship, Drug; Electric Stimulation; Endpoint Determination; Female; Hot Temperature; Humans; Hyperalgesia; Infusions, Intravenous; Ketamine; Male; Models, Statistical; Pain; Pain Measurement; Pain Threshold; Sex Characteristics; Young Adult | 2009 |
Exploring the pharmacokinetics of oral ketamine in children undergoing burns procedures.
Topics: Administration, Oral; Anesthetics, Dissociative; Biological Availability; Biotransformation; Burns; Child; Child, Preschool; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Infant; Infusions, Intravenous; Injections, Intravenous; Ketamine; Male; Pain | 2011 |
Nonselective and NR2B-selective N-methyl-D-aspartic acid receptor antagonists produce antinociception and long-term relief of allodynia in acute and neuropathic pain.
Topics: Acute Disease; Analgesics; Animals; Chronic Disease; Cold Temperature; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Foot Injuries; Hyperalgesia; Infrared Rays; Ketamine; Motor Activity; Neuralgia; Pain; Pain Measurement; Physical Stimulation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 2011 |
Response of chronic neuropathic pain syndromes to ketamine: a role for norketamine?
Topics: Humans; Ketamine; Pain; Pain, Intractable | 1995 |
Oral ketamine is antinociceptive in the rat formalin test: role of the metabolite, norketamine.
Topics: Administration, Oral; Animals; Behavior, Animal; Binding, Competitive; Central Nervous System; Formaldehyde; Injections, Spinal; Ketamine; Male; Nociceptors; Osmolar Concentration; Pain; Rats; Rats, Sprague-Dawley | 1999 |