nodosin has been researched along with Edema* in 1 studies
1 other study(ies) available for nodosin and Edema
| Article | Year |
|---|---|
Anti-inflammatory function of Nodosin via inhibition of IL-2.
In order to explore the anti-inflammatory effects of Nodosin from Isodon serra, a traditional Chinese herb medicine, mouse T lymphocytes were incubated with Nodosin. In the current study, Nodosin suppressed the overproduction of the T lymphocytes; moreover, cell mitosis cycle was modulated by interfering with DNA replication in G1 stages via inhibition of IL-2 cytokine secretion at the mRNA level by Nodosin. Interestingly, Xylene-induced mouse tumescence model results suggested Nodosin depressed the murine ear-swelling extent and the level of IL-2 in the blood serum. Finally, Nodosin possessed significant anti-inflammatory effects and is a potential candidate for further clinical trial. Topics: Animals; Anti-Inflammatory Agents; Cell Cycle; Diterpenes; DNA Replication; Drugs, Chinese Herbal; Ear; Edema; Female; Interleukin-2; Isodon; Male; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Components, Aerial; RNA, Messenger; T-Lymphocytes; Xylenes | 2010 |