Page last updated: 2024-10-19

nitrites and Ache

nitrites has been researched along with Ache in 37 studies

Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)

Research Excerpts

ExcerptRelevanceReference
"This study was carried out to investigate the effect of amentoflavone isolated from methanolic root extract of CF on lipopolysaccharide (LPS)-induced neuroinflammatory cascade of events associated to the oxidative and nitrative stress, and TNF-α production in rat astrocytoma cell line (C6) and human monocytic leukemia cell line (THP-1), respectively."7.79Evaluation of amentoflavone isolated from Cnestis ferruginea Vahl ex DC (Connaraceae) on production of inflammatory mediators in LPS stimulated rat astrocytoma cell line (C6) and THP-1 cells. ( Adeyemi, OO; Chaturvedi, JP; Ishola, IO; Narender, T; Rai, S; Rajasekar, N; Shukla, R, 2013)
"Intrathecal administration of alpha(2) adrenergic agonists, such as clonidine, is capable of alleviating neuropathic pain."7.70Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain. ( Chen, SR; Eisenach, J; Pan, HL; Xu, Z, 2000)
"Pretreatment with substance P (1-7) (400 pmol) produced a significant reduction on the elevated concentrations of glutamate and NO metabolites evoked by i."5.34Intrathecal substance P (1-7) prevents morphine-evoked spontaneous pain behavior via spinal NMDA-NO cascade. ( Komatsu, T; Kuwahata, H; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Tsuzuki, M; Watanabe, C, 2007)
" In vivo animal models of phorbol 12-myristate 13-acetate (TPA)-induced ear edema and acetic acid-induced writhing response tests were used to analyze the in vivo anti-inflammatory effects and anti-nociceptive effects of DP extract, respectively."3.83Potent Anti-inflammatory and Analgesic Actions of the Chloroform Extract of Dendropanax morbifera Mediated by the Nrf2/HO-1 Pathway. ( Akram, M; Bae, ON; Kim, CY; Kim, ES; Kim, KA; Lee, JS; Syed, AS, 2016)
"More studies are still warranted in similar rodent models of pain and depression, so, that the present findings can be further substantiated to establish the clinical effectiveness of berberine in a subset of patients suffering from pain as well as depression."3.79Possible involvement of oxido-nitrosative stress induced neuro-inflammatory cascade and monoaminergic pathway: underpinning the correlation between nociceptive and depressive behaviour in a rodent model. ( Arora, V; Chopra, K, 2013)
"This study was carried out to investigate the effect of amentoflavone isolated from methanolic root extract of CF on lipopolysaccharide (LPS)-induced neuroinflammatory cascade of events associated to the oxidative and nitrative stress, and TNF-α production in rat astrocytoma cell line (C6) and human monocytic leukemia cell line (THP-1), respectively."3.79Evaluation of amentoflavone isolated from Cnestis ferruginea Vahl ex DC (Connaraceae) on production of inflammatory mediators in LPS stimulated rat astrocytoma cell line (C6) and THP-1 cells. ( Adeyemi, OO; Chaturvedi, JP; Ishola, IO; Narender, T; Rai, S; Rajasekar, N; Shukla, R, 2013)
" The anti-nociceptive activities of MPP were measured using various experimental pain models including thermal nociception methods such as the tail immersion test and the hot plate test as well as chemical nociception methods like acetic acid-induced writhing test and formalin test."3.78Anti-inflammatory and anti-nociceptive properties of Prunus padus. ( Cha, DS; Choi, JH; Jeon, H, 2012)
"The results showed that the ethanolic extract of the Bougainvillea xbuttiana has significant anti-inflammatory and antinociceptive activities, by inhibition of nociception induced by acetic acid and paw oedema."3.78Anti-inflammatory and antinociceptive activities of the ethanolic extract of Bougainvillea xbuttiana. ( Alvarez Perez Gil, AL; Barbosa Navarro, L; Patipo Vera, M; Petricevich, VL, 2012)
" Also, the development of morphine dependence as assessed by naloxone-precipitated withdrawal manifestations was reduced by co-administration of aminoguanidine."3.73Attenuation of morphine tolerance and dependence by aminoguanidine in mice. ( Abdel-Hady, RH; Abdel-Rahman, S; Abdel-Zaher, AO; Aly, SA; Hamdy, MM, 2006)
"Intrathecal administration of alpha(2) adrenergic agonists, such as clonidine, is capable of alleviating neuropathic pain."3.70Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain. ( Chen, SR; Eisenach, J; Pan, HL; Xu, Z, 2000)
"The pain was evaluated by visual analogue scale (VAS)."2.90Phonopheresis Associated with Nanoparticle Gel from Phyllanthus amarus Relieves Pain by Reducing Oxidative Stress and Proinflammatory Markers in Adults with Knee Osteoarthritis. ( Decha, P; Jiraporn, T; Kanokwan, K; Pichaya, J; Pisittawoot, A, 2019)
"The hypothesis of decreased nitric oxide (NO) bioavailability in sickle cell disease (SCD) proposes that multiple factors leading to decreased NO production and increased consumption contributes to vaso-occlusion, pulmonary hypertension, and pain."1.56Sickle cell disease subjects and mouse models have elevated nitrite and cGMP levels in blood compartments. ( Almeida, LEF; Darbari, DS; de Souza Batista, CM; Finkel, JC; Kamimura, S; Nettleton, MY; Quezado, ZMN; Smith, ML; Spornick, N; Wakim, P; Walek, E, 2020)
"Pretreatment with substance P (1-7) (400 pmol) produced a significant reduction on the elevated concentrations of glutamate and NO metabolites evoked by i."1.34Intrathecal substance P (1-7) prevents morphine-evoked spontaneous pain behavior via spinal NMDA-NO cascade. ( Komatsu, T; Kuwahata, H; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Tsuzuki, M; Watanabe, C, 2007)
" Acute and chronic administration of 1% or 2."1.33Nitric oxide and c-Jun N-terminal kinase are involved in the development of dark neurons induced by inflammatory pain. ( Ahmadiani, A; Hassanzadeh, P, 2006)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19906 (16.22)18.7374
1990's1 (2.70)18.2507
2000's19 (51.35)29.6817
2010's9 (24.32)24.3611
2020's2 (5.41)2.80

Authors

AuthorsStudies
Pușcașu, C1
Ungurianu, A1
Șeremet, OC1
Andrei, C1
Mihai, DP1
Negreș, S1
Decha, P1
Kanokwan, K1
Jiraporn, T1
Pichaya, J1
Pisittawoot, A1
Almeida, LEF1
Kamimura, S1
de Souza Batista, CM1
Spornick, N1
Nettleton, MY1
Walek, E1
Smith, ML1
Finkel, JC1
Darbari, DS1
Wakim, P1
Quezado, ZMN1
Khan, S1
Shehzad, O1
Chun, J1
Kim, YS1
Arora, V1
Chopra, K1
Akram, M1
Kim, KA1
Kim, ES1
Syed, AS1
Kim, CY1
Lee, JS1
Bae, ON1
Jung, HJ1
Song, YS1
Lim, CJ1
Park, EH1
Rodriguez Peña, M1
Alescio, L1
Russell, A1
Lourenco da Cunha, J1
Alzu, G1
Bardoneschi, E1
BONNECARRERE, E1
LOCKHART, J1
Mehrotra, A1
Shanbhag, R1
Chamallamudi, MR1
Singh, VP1
Mudgal, J1
Lee, KH1
Kim, TH1
Lee, WC1
Kim, SH1
Lee, SY1
Lee, SM1
Choi, JH1
Cha, DS1
Jeon, H1
Alvarez Perez Gil, AL1
Barbosa Navarro, L1
Patipo Vera, M1
Petricevich, VL1
Ishola, IO1
Chaturvedi, JP1
Rai, S1
Rajasekar, N1
Adeyemi, OO1
Shukla, R1
Narender, T1
De León, EJ2
Alcaraz, MJ2
Dominguez, JN2
Charris, J2
Terencio, MC2
DURRER, D1
Costa, B2
Trovato, AE2
Colleoni, M2
Giagnoni, G2
Zarini, E1
Croci, T1
Khattab, MM1
El-Hadiyah, TM1
Al-Shabanah, OA1
Raza, M1
Hassanzadeh, P1
Ahmadiani, A1
Escandell, JM1
Recio, MC1
Máñez, S1
Giner, RM1
Cerdá-Nicolás, M1
Ríos, JL1
Savaris, RF1
Teixeira, LM1
Torres, TG1
Abdel-Zaher, AO1
Hamdy, MM1
Aly, SA1
Abdel-Hady, RH1
Abdel-Rahman, S1
Siniscalco, D1
Comelli, F1
Sotgiu, ML1
Maione, S1
Rossi, F1
Vareniuk, I1
Pavlov, IA1
Drel, VR1
Lyzogubov, VV1
Ilnytska, O1
Bell, SR1
Tibrewala, J1
Groves, JT1
Obrosova, IG1
Joharchi, K1
Jorjani, M1
Uludag, O1
Tunctan, B1
Altug, S1
Zengil, H1
Abacioglu, N1
Sakurada, T1
Komatsu, T1
Kuwahata, H1
Watanabe, C1
Orito, T1
Sakurada, C1
Tsuzuki, M1
Sakurada, S1
Regan, EA1
Bowler, RP1
Crapo, JD1
Bruyneel, K1
Kirby, B1
Kimura, S1
Watanabe, K1
Yajiri, Y1
Motegi, T1
Masuya, Y1
Shibuki, K1
Uchiyama, S1
Homma, T1
Takahashi, HE1
Xu, Z1
Chen, SR1
Eisenach, J1
Pan, HL1
Grover, VS1
Sharma, A1
Singh, M1
Vetter, G1
Geisslinger, G1
Tegeder, I1
Popescu, P1
Gherasim, L1

Reviews

1 review available for nitrites and Ache

ArticleYear
Drug therapy for hypertension and ischemic heart disease.
    International anesthesiology clinics, 1980,Winter, Volume: 18, Issue:4

    Topics: Adrenergic beta-Agonists; Adult; Antihypertensive Agents; Arrhythmias, Cardiac; Cardiac Glycosides;

1980

Trials

1 trial available for nitrites and Ache

ArticleYear
Phonopheresis Associated with Nanoparticle Gel from Phyllanthus amarus Relieves Pain by Reducing Oxidative Stress and Proinflammatory Markers in Adults with Knee Osteoarthritis.
    Chinese journal of integrative medicine, 2019, Volume: 25, Issue:9

    Topics: Adult; Aged; Antioxidants; Biomarkers; Gels; Humans; Inflammation Mediators; Middle Aged; Nanopartic

2019

Other Studies

35 other studies available for nitrites and Ache

ArticleYear
The Influence of Sildenafil-Metformin Combination on Hyperalgesia and Biochemical Markers in Diabetic Neuropathy in Mice.
    Medicina (Kaunas, Lithuania), 2023, Jul-27, Volume: 59, Issue:8

    Topics: Animals; Biomarkers; Diabetes Mellitus; Diabetic Neuropathies; Hyperalgesia; Hypoglycemic Agents; In

2023
Sickle cell disease subjects and mouse models have elevated nitrite and cGMP levels in blood compartments.
    Nitric oxide : biology and chemistry, 2020, 01-01, Volume: 94

    Topics: Adult; Anemia, Sickle Cell; Animals; Biological Availability; Cyclic GMP; Disease Models, Animal; Hu

2020
Mechanism underlying anti-hyperalgesic and anti-allodynic properties of anomalin in both acute and chronic inflammatory pain models in mice through inhibition of NF-κB, MAPKs and CREB signaling cascades.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Acute Disease; Adenosine Triphosphate; Analgesics; Animals; Chronic Disease; Coumarins; Cyclic AMP R

2013
Possible involvement of oxido-nitrosative stress induced neuro-inflammatory cascade and monoaminergic pathway: underpinning the correlation between nociceptive and depressive behaviour in a rodent model.
    Journal of affective disorders, 2013, Volume: 151, Issue:3

    Topics: Animals; Berberine; Caspase 3; Cerebral Cortex; Depression; Disease Models, Animal; Dopamine; Hippoc

2013
Potent Anti-inflammatory and Analgesic Actions of the Chloroform Extract of Dendropanax morbifera Mediated by the Nrf2/HO-1 Pathway.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Araliaceae; Chloroform; Cytokines; Dinop

2016
Anti-inflammatory, anti-angiogenic and anti-nociceptive activities of an ethanol extract of Salvia plebeia R. Brown.
    Journal of ethnopharmacology, 2009, Nov-12, Volume: 126, Issue:2

    Topics: Acetic Acid; Analgesics; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; B

2009
Predictors of improved seminal parameters and fertility after varicocele repair in young adults.
    Andrologia, 2009, Volume: 41, Issue:5

    Topics: Adolescent; Adult; Fertility; Humans; Male; Nitrites; Organ Size; Pain; Predictive Value of Tests; S

2009
Some considerations on the treatment of flank pain syndromes with amyl nitrite.
    Archivos uruguayos de medicina, cirugia y especialidades, 1945, Volume: 27

    Topics: Amyl Nitrite; Back Pain; Humans; Lumbosacral Region; Nitrites; Pain

1945
Treatment of hepato-vesicular colic attack with amyl nitrite.
    Bulletin de l'Academie de medecine, 1946, Volume: 130, Issue:3-5

    Topics: Amyl Nitrite; Bile Duct Diseases; Biliary Tract; Gallbladder Diseases; Humans; Nitrites; Pain

1946
Ameliorative effect of caffeic acid against inflammatory pain in rodents.
    European journal of pharmacology, 2011, Volume: 666, Issue:1-3

    Topics: Acetates; Animals; Behavior, Animal; Caffeic Acids; Carrageenan; Formaldehyde; Inflammation; Lipopol

2011
Anti-inflammatory and analgesic effects of human placenta extract.
    Natural product research, 2011, Volume: 25, Issue:11

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Blotting, Western; Carrageena

2011
Anti-inflammatory and anti-nociceptive properties of Prunus padus.
    Journal of ethnopharmacology, 2012, Nov-21, Volume: 144, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Edema; Formaldehyde; H

2012
Anti-inflammatory and antinociceptive activities of the ethanolic extract of Bougainvillea xbuttiana.
    Journal of ethnopharmacology, 2012, Dec-18, Volume: 144, Issue:3

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Cytokines

2012
Evaluation of amentoflavone isolated from Cnestis ferruginea Vahl ex DC (Connaraceae) on production of inflammatory mediators in LPS stimulated rat astrocytoma cell line (C6) and THP-1 cells.
    Journal of ethnopharmacology, 2013, Mar-27, Volume: 146, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Astrocytoma; Biflavonoids; Carrageenan; Cell Line; C

2013
1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one, a chalcone derivative with analgesic, anti-inflammatory and immunomodulatory properties.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2003, Volume: 52, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; B

2003
[Therapy of stenocardiac pains with nitroglycerin].
    Nederlands tijdschrift voor geneeskunde, 1960, Jan-09, Volume: 104

    Topics: Angina Pectoris; Nitrites; Nitroglycerin; Pain

1960
A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:9

    Topics: Abdominal Injuries; Administration, Oral; Animals; Arthritis, Experimental; Blood Platelets; Cell Li

2003
Effect of the cannabinoid CB1 receptor antagonist, SR141716, on nociceptive response and nerve demyelination in rodents with chronic constriction injury of the sciatic nerve.
    Pain, 2005, Volume: 116, Issue:1-2

    Topics: Analysis of Variance; Animals; Blotting, Western; Cannabinoid Receptor Antagonists; Constriction; De

2005
Modification by L-NAME of codeine induced analgesia: possible role of nitric oxide.
    Receptors & channels, 2004, Volume: 10, Issue:5-6

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Codeine; Dose-Response Relationship, Drug; Drug

2004
Nitric oxide and c-Jun N-terminal kinase are involved in the development of dark neurons induced by inflammatory pain.
    Synapse (New York, N.Y.), 2006, Volume: 59, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Formaldehyde; Immunohistochemistry; Inflammation; Irritan

2006
Dihydrocucurbitacin B, isolated from Cayaponia tayuya, reduces damage in adjuvant-induced arthritis.
    European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Experiment

2006
Bladder tenderness as a physical sign for diagnosing cystitis in women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2006, Volume: 93, Issue:3

    Topics: Case-Control Studies; Cystitis, Interstitial; Female; Humans; Likelihood Functions; Nitrites; Pain;

2006
Attenuation of morphine tolerance and dependence by aminoguanidine in mice.
    European journal of pharmacology, 2006, Jul-01, Volume: 540, Issue:1-3

    Topics: Analgesics; Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Brain; Dizocilpine Maleate; Dru

2006
AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain.
    British journal of pharmacology, 2006, Volume: 148, Issue:7

    Topics: Analgesics; Animals; Apoptosis; Arachidonic Acids; bcl-2-Associated X Protein; Behavior, Animal; Blo

2006
Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice.
    Experimental neurology, 2007, Volume: 205, Issue:2

    Topics: Anesthesia; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diabetic Nephropathies;

2007
The role of nitric oxide in diabetes-induced changes of morphine tolerance in rats.
    European journal of pharmacology, 2007, Sep-10, Volume: 570, Issue:1-3

    Topics: Analgesics, Opioid; Animals; Arginine; Diabetes Mellitus, Experimental; Drug Tolerance; Guanidines;

2007
Twenty-four-hour variation of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway demonstrated by the mouse visceral pain model.
    Chronobiology international, 2007, Volume: 24, Issue:3

    Topics: Abdominal Pain; Analgesics; Animals; Arginine; Benzoquinones; Circadian Rhythm; Cyclic GMP; Enzyme I

2007
Intrathecal substance P (1-7) prevents morphine-evoked spontaneous pain behavior via spinal NMDA-NO cascade.
    Biochemical pharmacology, 2007, Sep-01, Volume: 74, Issue:5

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Glutamic Acid; Male; Morphine; N-Methylaspart

2007
Joint fluid antioxidants are decreased in osteoarthritic joints compared to joints with macroscopically intact cartilage and subacute injury.
    Osteoarthritis and cartilage, 2008, Volume: 16, Issue:4

    Topics: Age Factors; Cartilage, Articular; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Female;

2008
Chest pain with normal coronary arteries.
    Lancet (London, England), 1980, Mar-01, Volume: 1, Issue:8166

    Topics: Angina Pectoris; Coronary Angiography; Humans; Nitrites; Pain; Reference Values; Thorax

1980
Cerebrospinal fluid nitric oxide metabolites in painful diseases.
    Neuroreport, 1999, Feb-05, Volume: 10, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Appendicitis; Female; Fractures, Bone; Humans; Lumbosacral Re

1999
Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain.
    Brain research, 2000, Apr-10, Volume: 861, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Male; Muscarinic Antagonists; Nicotinic Antagonists;

2000
Role of nitric oxide in diabetes-induced attenuation of antinociceptive effect of morphine in mice.
    European journal of pharmacology, 2000, Jul-07, Volume: 399, Issue:2-3

    Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Female; Guanidines; Male; Mice; Morphi

2000
Release of glutamate, nitric oxide and prostaglandin E2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation.
    Pain, 2001, Volume: 92, Issue:1-2

    Topics: Animals; Dinoprostone; Glutamic Acid; Glycerol; Lactic Acid; Male; Microdialysis; Nitrates; Nitric O

2001
[Current problems in diagnosis and treatment of angina pectoris].
    Medicina interna, 1972, Volume: 24, Issue:8

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angiography; Anticoagulants; Benzofurans; Coronary Ang

1972