nitrates has been researched along with Fibrosis in 21 studies
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome." | 7.74 | Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008) |
| "The lipid-lowering agent probucol may be efficacious, through its antioxidant properties, to limit and reverse the vascular endothelial dysfunction associated with left ventricular hypertrophy (LVH)." | 7.73 | Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy. ( Aubin, MC; Carrier, M; Perrault, LP; Shi, YF; Tardif, JC, 2006) |
| " In acute anti-thy-1 glomerulonephritis prefeeding with the NO precursor L-arginine increases mesangial cell injury and the subsequent fibrosis." | 7.72 | L-arginine supplementation accelerates renal fibrosis and shortens life span in experimental lupus nephritis. ( Border, WA; Krämer, S; Neumayer, HH; Noble, NA; Peters, H; Rückert, M, 2003) |
| "NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis." | 7.72 | NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis. ( Daig, U; Krämer, S; Liefeldt, L; Martini, S; Neumayer, HH; Peters, H; Rückert, M; Schäper, F, 2003) |
| " Here we assess the therapeutic effect of L-arginine supplementation, which has been shown to reduce fibrosis in a number of hypertensive models, given alone or in combination with low protein diet and started 24 hours after disease induction." | 7.70 | Tandem antifibrotic actions of L-arginine supplementation and low protein diet during the repair phase of experimental glomerulonephritis. ( Border, WA; Noble, NA; Peters, H, 2000) |
| "Fibrosis was minimal in groups 1 through 3, but was significantly increased by L-NAME." | 5.33 | Dietary arginine supplementation attenuates renal damage after relief of unilateral ureteral obstruction in rats. ( Chen, J; El Chaar, M; Felsen, D; Gallagher, R; Ito, K; Khodadadian, JJ; Poppas, DP; Seshan, SV; Vaughan, ED, 2005) |
| " We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome." | 3.74 | Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008) |
| "The lipid-lowering agent probucol may be efficacious, through its antioxidant properties, to limit and reverse the vascular endothelial dysfunction associated with left ventricular hypertrophy (LVH)." | 3.73 | Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy. ( Aubin, MC; Carrier, M; Perrault, LP; Shi, YF; Tardif, JC, 2006) |
| " In acute anti-thy-1 glomerulonephritis prefeeding with the NO precursor L-arginine increases mesangial cell injury and the subsequent fibrosis." | 3.72 | L-arginine supplementation accelerates renal fibrosis and shortens life span in experimental lupus nephritis. ( Border, WA; Krämer, S; Neumayer, HH; Noble, NA; Peters, H; Rückert, M, 2003) |
| "NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis." | 3.72 | NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis. ( Daig, U; Krämer, S; Liefeldt, L; Martini, S; Neumayer, HH; Peters, H; Rückert, M; Schäper, F, 2003) |
| " Here we assess the therapeutic effect of L-arginine supplementation, which has been shown to reduce fibrosis in a number of hypertensive models, given alone or in combination with low protein diet and started 24 hours after disease induction." | 3.70 | Tandem antifibrotic actions of L-arginine supplementation and low protein diet during the repair phase of experimental glomerulonephritis. ( Border, WA; Noble, NA; Peters, H, 2000) |
| "Maternal undernutrition is known to reduce glomerular number but it may also affect tubulointerstitium, capillary density, and response to oxidative stress." | 1.51 | Maternal undernutrition aggravates renal tubular necrosis and interstitial fibrosis after unilateral ureteral obstruction in male rat offspring. ( Abe, T; Awazu, M; Hashiguchi, A; Hida, M, 2019) |
| "CA(NO) from SSc patients with interstitial lung disease (ILD) (n=26, 8." | 1.35 | Exhaled nitric oxide, but not serum nitrite and nitrate, is a marker of interstitial lung disease in systemic sclerosis. ( Cabane, J; Dinh-Xuan, AT; Duong-Quy, S; Hua-Huy, T; Le-Dong, NN; Tiev, KP, 2009) |
| "Fibrosis was minimal in groups 1 through 3, but was significantly increased by L-NAME." | 1.33 | Dietary arginine supplementation attenuates renal damage after relief of unilateral ureteral obstruction in rats. ( Chen, J; El Chaar, M; Felsen, D; Gallagher, R; Ito, K; Khodadadian, JJ; Poppas, DP; Seshan, SV; Vaughan, ED, 2005) |
| "Gentamicin-treated rats presented a transitory increase in plasma creatinine levels." | 1.33 | Increased expression of p38 mitogen-activated protein kinase is related to the acute renal lesions induced by gentamicin. ( Balbi, AP; Coimbra, TM; Costa, RS; Volpini, RA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 11 (52.38) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 5 (23.81) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 1 |
| Zhuge, Z | 1 |
| Carvalho, LRRA | 1 |
| Braga, VA | 1 |
| Lucena, RB | 1 |
| Li, S | 1 |
| Schiffer, TA | 1 |
| Han, H | 1 |
| Weitzberg, E | 1 |
| Lundberg, JO | 1 |
| Carlström, M | 1 |
| Xue, K | 1 |
| Chen, S | 1 |
| Chai, J | 1 |
| Yan, W | 1 |
| Zhu, X | 1 |
| Ji, D | 1 |
| Wu, Y | 1 |
| Liu, H | 1 |
| Wang, W | 1 |
| Petrick, HL | 1 |
| Ogilvie, LM | 1 |
| Brunetta, HS | 1 |
| Robinson, A | 1 |
| Kirsh, AJ | 1 |
| Barbeau, PA | 1 |
| Handy, RM | 1 |
| Coyle-Asbil, B | 1 |
| Gianetto-Hill, C | 1 |
| Dennis, KMJH | 1 |
| van Loon, LJC | 1 |
| Chabowski, A | 1 |
| Schertzer, JD | 1 |
| Allen-Vercoe, E | 1 |
| Simpson, JA | 1 |
| Holloway, GP | 1 |
| Awazu, M | 1 |
| Abe, T | 1 |
| Hashiguchi, A | 1 |
| Hida, M | 1 |
| Giam, B | 1 |
| Nomura, H | 1 |
| Kuruppu, S | 1 |
| Chu, PY | 1 |
| Essid, S | 1 |
| Kiriazis, H | 1 |
| Du, XJ | 1 |
| Kaye, DM | 1 |
| Rajapakse, NW | 1 |
| Gee, LC | 1 |
| Massimo, G | 1 |
| Lau, C | 1 |
| Primus, C | 1 |
| Fernandes, D | 1 |
| Chen, J | 2 |
| Rathod, KS | 1 |
| Hamers, AJP | 1 |
| Filomena, F | 1 |
| Nuredini, G | 1 |
| Ibrahim, AS | 1 |
| Khambata, RS | 1 |
| Gupta, AK | 1 |
| Moon, JC | 1 |
| Kapil, V | 1 |
| Ahluwalia, A | 1 |
| Bunbupha, S | 1 |
| Prachaney, P | 1 |
| Kukongviriyapan, U | 1 |
| Kukongviriyapan, V | 1 |
| Welbat, JU | 1 |
| Pakdeechote, P | 1 |
| Sun, Y | 1 |
| Carretero, OA | 1 |
| Xu, J | 1 |
| Rhaleb, NE | 1 |
| Yang, JJ | 1 |
| Pagano, PJ | 1 |
| Yang, XP | 1 |
| Tiev, KP | 1 |
| Le-Dong, NN | 1 |
| Duong-Quy, S | 1 |
| Hua-Huy, T | 1 |
| Cabane, J | 1 |
| Dinh-Xuan, AT | 1 |
| Sasser, JM | 1 |
| Moningka, NC | 1 |
| Cunningham, MW | 1 |
| Croker, B | 1 |
| Baylis, C | 1 |
| Singh, K | 1 |
| Singh, T | 1 |
| Sharma, PL | 1 |
| Peters, H | 3 |
| Border, WA | 2 |
| Rückert, M | 2 |
| Krämer, S | 2 |
| Neumayer, HH | 2 |
| Noble, NA | 2 |
| Daig, U | 1 |
| Martini, S | 1 |
| Schäper, F | 1 |
| Liefeldt, L | 1 |
| Xia, CF | 1 |
| Bledsoe, G | 1 |
| Chao, L | 2 |
| Chao, J | 2 |
| Ito, K | 1 |
| Seshan, SV | 1 |
| Khodadadian, JJ | 1 |
| Gallagher, R | 1 |
| El Chaar, M | 1 |
| Vaughan, ED | 1 |
| Poppas, DP | 1 |
| Felsen, D | 1 |
| Volpini, RA | 1 |
| Balbi, AP | 1 |
| Costa, RS | 1 |
| Coimbra, TM | 1 |
| Aubin, MC | 1 |
| Carrier, M | 1 |
| Shi, YF | 1 |
| Tardif, JC | 1 |
| Perrault, LP | 1 |
| Matsuzaki, G | 1 |
| Ishizaka, N | 1 |
| Furuta, K | 1 |
| Hongo, M | 1 |
| Saito, K | 1 |
| Sakurai, R | 1 |
| Koike, K | 1 |
| Nagai, R | 1 |
| Wolf, WC | 1 |
| Yoshida, H | 1 |
| Agata, J | 1 |
| Reichen, J | 1 |
1 review available for nitrates and Fibrosis
| Article | Year |
|---|---|
Liver function and pharmacological considerations in pathogenesis and treatment of portal hypertension.
Topics: Blood Circulation; Calcium Channel Blockers; Fibrosis; Humans; Hypertension, Portal; Liver; Methods; | 1990 |
20 other studies available for nitrates and Fibrosis
| Article | Year |
|---|---|
Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1α pathway.
Topics: AMP-Activated Protein Kinases; Animals; Female; Fibrosis; Humans; Kidney; Kidney Diseases; Lipid Met | 2022 |
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis
Topics: Animals; Chemokine CXCL12; Collagen Type I; Cyclic AMP Receptor Protein; Disease Models, Animal; Fib | 2023 |
Dietary Nitrate and Corresponding Gut Microbiota Prevent Cardiac Dysfunction in Obese Mice.
Topics: Animals; Diet, High-Fat; Dysbiosis; Fibrosis; Gastrointestinal Microbiome; Glucose Intolerance; Hear | 2023 |
Maternal undernutrition aggravates renal tubular necrosis and interstitial fibrosis after unilateral ureteral obstruction in male rat offspring.
Topics: Animals; Disease Models, Animal; Female; Fibrosis; Kidney; Kidney Tubular Necrosis, Acute; Male; Mal | 2019 |
Endothelial-specific overexpression of cationic amino acid transporter-1 prevents loss of kidney function in heart failure.
Topics: Animals; Blood Pressure; Body Weight; Cardiomyopathy, Dilated; Cationic Amino Acid Transporter 1; En | 2020 |
Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide.
Topics: Animals; Cardiomegaly; Case-Control Studies; Clinical Studies as Topic; Disease Models, Animal; Fibr | 2022 |
Asiatic acid alleviates cardiovascular remodelling in rats with L-NAME-induced hypertension.
Topics: Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Collagen; Disease Models, Anima | 2015 |
Deletion of inducible nitric oxide synthase provides cardioprotection in mice with 2-kidney, 1-clip hypertension.
Topics: Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Gene Deletion; Hypertension, Renovascular | 2009 |
Exhaled nitric oxide, but not serum nitrite and nitrate, is a marker of interstitial lung disease in systemic sclerosis.
Topics: Adult; Biomarkers; Case-Control Studies; Exhalation; Female; Fibrosis; Humans; Lung Diseases, Inters | 2009 |
Asymmetric dimethylarginine in angiotensin II-induced hypertension.
Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Fibrosis; Hypertension, Renal; K | 2010 |
Beneficial effects of angiotensin (1-7) in diabetic rats with cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Di | 2011 |
L-arginine supplementation accelerates renal fibrosis and shortens life span in experimental lupus nephritis.
Topics: Albuminuria; Amino Acids; Animals; Arginine; Autoantibodies; Blood Urea Nitrogen; DNA; Extracellular | 2003 |
NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Enzyme Inhibitors; Fibronectins; Fibrosis; Gene Expr | 2003 |
Kallikrein gene transfer reduces renal fibrosis, hypertrophy, and proliferation in DOCA-salt hypertensive rats.
Topics: Animals; Cell Cycle Proteins; Cell Division; Cyclic GMP; Cyclin-Dependent Kinase Inhibitor p27; Deso | 2005 |
Dietary arginine supplementation attenuates renal damage after relief of unilateral ureteral obstruction in rats.
Topics: Animals; Arginine; Cyclic GMP; Dietary Supplements; Enzyme Inhibitors; Fibroblasts; Fibrosis; Glomer | 2005 |
Increased expression of p38 mitogen-activated protein kinase is related to the acute renal lesions induced by gentamicin.
Topics: Animals; Anti-Bacterial Agents; Blotting, Western; Creatinine; Female; Fibrosis; Gentamicins; Immuno | 2006 |
Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy.
Topics: Angiotensin II; Animals; Antioxidants; Bradykinin; Coronary Vessels; Cyclic GMP; Endothelium, Vascul | 2006 |
Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium | 2008 |
Tandem antifibrotic actions of L-arginine supplementation and low protein diet during the repair phase of experimental glomerulonephritis.
Topics: Animals; Arginine; Culture Techniques; Dietary Proteins; Fibrosis; Glomerulonephritis; Kidney; Kidne | 2000 |
Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure.
Topics: Adenoviridae; Animals; Blood Pressure; Blood Urea Nitrogen; Cardiomegaly; Cyclic GMP; Fibrosis; Gene | 2000 |