modafinil and Coma
modafinil has been researched along with Coma in 2 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The vigilance promoting drug modafinil prevented recurrent episodes of stupor and coma in this patient at a dose of 200 mg/day for a period of six months." | 3.72 | Modafinil in endozepine stupor. A case report. ( Ahmed, I; Scott, S, 2004) |
| "Modafinil promotes attention, concentration and maintains wakefulness in a patient with narcolepsy, obstructive sleep apnea and shift work sleep disorders." | 1.46 | Does Modafinil improve the level of consciousness for people with a prolonged disorder of consciousness? a retrospective pilot study. ( Dhamapurkar, SK; Rose, A; Shiel, A; Watson, P; Wilson, BA, 2017) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Dhamapurkar, SK | 1 |
| Wilson, BA | 1 |
| Rose, A | 1 |
| Watson, P | 1 |
| Shiel, A | 1 |
| Scott, S | 1 |
| Ahmed, I | 1 |
Other Studies
2 other studies available for modafinil and Coma
| Article | Year |
|---|---|
Does Modafinil improve the level of consciousness for people with a prolonged disorder of consciousness? a retrospective pilot study.
Topics: Adult; Aged; Benzhydryl Compounds; Brain Injuries, Traumatic; Cognition; Coma; Female; Humans; Male; | 2017 |
Modafinil in endozepine stupor. A case report.
Topics: Administration, Oral; Aged; Benzhydryl Compounds; Central Nervous System Stimulants; Coma; Diazepam | 2004 |