mitomycin has been researched along with Scleritis in 11 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Scleritis: Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to report a case of infective necrotizing scleritis following XEN Gel Stent with mitomycin-C." | 8.12 | Infective Necrotizing Scleritis After XEN Gel Stent With Mitomycin-C. ( Kingston, EJ; Lusthaus, JA; McCluskey, PJ; Raman, P; Symes, RJ; Zagora, SL, 2022) |
| "Adjunctive intraoperative mitomycin C increases the success of glaucoma filtering surgery, but also the postoperative complications." | 7.69 | Scleritis after glaucoma filtering surgery with mitomycin C. ( Fourman, S, 1995) |
| "Necrotizing scleritis is a severe complication that can arise after cosmetic eye-whitening conjunctivectomy with MMC." | 5.48 | Necrotizing Scleritis After Cosmetic Conjunctivectomy With Mitomycin C. ( Alotaibi, MH; Choi, S; Hwang, DG; Ji, YW; Jung, JW; Park, SY; Seo, KY; Stulting, RD, 2018) |
| "The purpose of this study was to report a case of infective necrotizing scleritis following XEN Gel Stent with mitomycin-C." | 4.12 | Infective Necrotizing Scleritis After XEN Gel Stent With Mitomycin-C. ( Kingston, EJ; Lusthaus, JA; McCluskey, PJ; Raman, P; Symes, RJ; Zagora, SL, 2022) |
| "To report a case of necrotizing scleritis after pterygium surgery with conjunctival autografting (CA) and intraoperative Mitomycin C (MMC) and its treatment with amniotic membrane transplantation (AMT) and systemic steroid." | 3.76 | Successful treatment of necrotizing scleritis after conjunctival autografting for pterygium with amniotic membrane transplantation. ( Akova, YA; Borazan, M; Karalezli, A; Kucukerdonmez, C, 2010) |
| "Sixteen (80%) of 20 cases developed severe scleral necrosis that required tectonic surgery after bare sclera pterygium excision with mitomycin C or beta-irradiation." | 3.72 | Tectonic corneal lamellar grafting for severe scleral melting after pterygium surgery. ( Tan, DT; Ti, SE, 2003) |
| "Adjunctive intraoperative mitomycin C increases the success of glaucoma filtering surgery, but also the postoperative complications." | 3.69 | Scleritis after glaucoma filtering surgery with mitomycin C. ( Fourman, S, 1995) |
| "Necrotizing scleritis is a severe complication that can arise after cosmetic eye-whitening conjunctivectomy with MMC." | 1.48 | Necrotizing Scleritis After Cosmetic Conjunctivectomy With Mitomycin C. ( Alotaibi, MH; Choi, S; Hwang, DG; Ji, YW; Jung, JW; Park, SY; Seo, KY; Stulting, RD, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Kingston, EJ | 1 |
| Zagora, SL | 1 |
| Symes, RJ | 1 |
| Raman, P | 1 |
| McCluskey, PJ | 1 |
| Lusthaus, JA | 1 |
| Ji, YW | 1 |
| Park, SY | 1 |
| Jung, JW | 1 |
| Choi, S | 1 |
| Alotaibi, MH | 1 |
| Stulting, RD | 1 |
| Hwang, DG | 1 |
| Seo, KY | 1 |
| Dean, WH | 1 |
| Turner, SA | 1 |
| McNaught, AI | 1 |
| Parada-Vásquez, RH | 1 |
| Benítez-Castrillón, PC | 1 |
| de León-Ortega, JE | 1 |
| León-Roldán, CR | 1 |
| Karalezli, A | 1 |
| Kucukerdonmez, C | 1 |
| Borazan, M | 1 |
| Akova, YA | 1 |
| Aydin, A | 1 |
| Aksoy, Y | 1 |
| Unal, MH | 1 |
| Ersanli, D | 1 |
| Ti, SE | 1 |
| Tan, DT | 1 |
| Singh, RP | 1 |
| McCluskey, P | 1 |
| Kersten, RC | 1 |
| Kulwin, DR | 1 |
| Fourman, S | 1 |
| Hsiao, CH | 1 |
| Chen, JJ | 1 |
| Huang, SC | 1 |
| Ma, HK | 1 |
| Chen, PY | 1 |
| Tsai, RJ | 1 |
11 other studies available for mitomycin and Scleritis
| Article | Year |
|---|---|
Infective Necrotizing Scleritis After XEN Gel Stent With Mitomycin-C.
Topics: Aged; Female; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Mitomy | 2022 |
Necrotizing Scleritis After Cosmetic Conjunctivectomy With Mitomycin C.
Topics: Adult; Alkylating Agents; Conjunctiva; Cosmetic Techniques; Female; Humans; Immunosuppressive Agents | 2018 |
Secondary glaucoma due to chronic scleritis: trabeculectomy in scleromalacia: a case report.
Topics: Aged; Alkylating Agents; Chronic Disease; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; I | 2014 |
Scleral patch graft in the management of necrotising scleritis with inflammation. A case report.
Topics: Allografts; Amnion; Female; Humans; Middle Aged; Mitomycin; Necrosis; Postoperative Complications; P | 2016 |
Successful treatment of necrotizing scleritis after conjunctival autografting for pterygium with amniotic membrane transplantation.
Topics: Adult; Amnion; Combined Modality Therapy; Conjunctiva; Female; Humans; Injections, Intravenous; Meth | 2010 |
[Necrotizing scleritis after pterygium surgery using mitomycin C].
Topics: Antibiotics, Antineoplastic; Female; Humans; Intraoperative Care; Middle Aged; Mitomycin; Ophthalmol | 2012 |
Tectonic corneal lamellar grafting for severe scleral melting after pterygium surgery.
Topics: Aged; Antibiotics, Antineoplastic; Combined Modality Therapy; Corneal Transplantation; Female; Graft | 2003 |
Scedosporium prolificans sclerokeratitis 10 years after pterygium excision with adjunctive mitomycin C.
Topics: Amphotericin B; Antibiotics, Antineoplastic; Antifungal Agents; Chemotherapy, Adjuvant; Drug Therapy | 2005 |
MMC in ONS decompression.
Topics: Adolescent; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Humans; Male; Mitomycin; Myelin S | 1996 |
Scleritis after glaucoma filtering surgery with mitomycin C.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Age | 1995 |
Intrascleral dissemination of infectious scleritis following pterygium excision.
Topics: Abscess; Adult; Aged; Antibiotics, Antineoplastic; Eye Infections, Bacterial; Female; Follow-Up Stud | 1998 |