Page last updated: 2024-11-06

mitomycin and Leprosy

mitomycin has been researched along with Leprosy in 2 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.

Research Excerpts

ExcerptRelevanceReference
"The effects of a bifunctional alkylating agent mitomycin C (MMC), an effective inducer of chromosome aberrations and sister-chromatid exchanges (SCEs), have been studied in untreated leprosy patients."7.68Differential sensitivity of peripheral blood lymphocytes of untreated leprosy patients to mitomycin C. ( D'Souza, D; Das, BC; Thomas, IM, 1990)
"The effects of a bifunctional alkylating agent mitomycin C (MMC), an effective inducer of chromosome aberrations and sister-chromatid exchanges (SCEs), have been studied in untreated leprosy patients."3.68Differential sensitivity of peripheral blood lymphocytes of untreated leprosy patients to mitomycin C. ( D'Souza, D; Das, BC; Thomas, IM, 1990)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stoner, GL1
Mshana, RN1
Touw, J1
Belehu, A1
D'Souza, D1
Das, BC1
Thomas, IM1

Other Studies

2 other studies available for mitomycin and Leprosy

ArticleYear
Studies on the defect in cell-mediated immunity in lepromatous leprosy using HLA-D-identical siblings. Absence of circulating suppressor cells and evidence that the defect is in the T-lymphocyte, rather than the monocyte, population.
    Scandinavian journal of immunology, 1982, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Cell Adhesion; Child; Epitopes; Female; Histocompatibility Antigens Class II; Hum

1982
Differential sensitivity of peripheral blood lymphocytes of untreated leprosy patients to mitomycin C.
    Mutation research, 1990, Volume: 240, Issue:2

    Topics: Cells, Cultured; Chromosome Aberrations; Chromosomes; Leprosy; Lymphocytes; Male; Mitomycin; Mitomyc

1990