mitomycin has been researched along with Leprosy in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of a bifunctional alkylating agent mitomycin C (MMC), an effective inducer of chromosome aberrations and sister-chromatid exchanges (SCEs), have been studied in untreated leprosy patients." | 7.68 | Differential sensitivity of peripheral blood lymphocytes of untreated leprosy patients to mitomycin C. ( D'Souza, D; Das, BC; Thomas, IM, 1990) |
| "The effects of a bifunctional alkylating agent mitomycin C (MMC), an effective inducer of chromosome aberrations and sister-chromatid exchanges (SCEs), have been studied in untreated leprosy patients." | 3.68 | Differential sensitivity of peripheral blood lymphocytes of untreated leprosy patients to mitomycin C. ( D'Souza, D; Das, BC; Thomas, IM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stoner, GL | 1 |
| Mshana, RN | 1 |
| Touw, J | 1 |
| Belehu, A | 1 |
| D'Souza, D | 1 |
| Das, BC | 1 |
| Thomas, IM | 1 |
2 other studies available for mitomycin and Leprosy
| Article | Year |
|---|---|
Studies on the defect in cell-mediated immunity in lepromatous leprosy using HLA-D-identical siblings. Absence of circulating suppressor cells and evidence that the defect is in the T-lymphocyte, rather than the monocyte, population.
Topics: Adolescent; Adult; Cell Adhesion; Child; Epitopes; Female; Histocompatibility Antigens Class II; Hum | 1982 |
Differential sensitivity of peripheral blood lymphocytes of untreated leprosy patients to mitomycin C.
Topics: Cells, Cultured; Chromosome Aberrations; Chromosomes; Leprosy; Lymphocytes; Male; Mitomycin; Mitomyc | 1990 |