Page last updated: 2024-10-31

mianserin and Fatigue

mianserin has been researched along with Fatigue in 5 studies

Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

ExcerptRelevanceReference
"Primary care patients with a major depressive disorder and 17-item Hamilton Rating Scale for Depression (17-HAM-D) score >18 were randomized to 24 weeks of treatment with mirtazapine 30-45 mg/day (n=99) or paroxetine 20-30 mg/day (n=98)."5.10A randomized, double-blind, 24-week study comparing the efficacy and tolerability of mirtazapine and paroxetine in depressed patients in primary care. ( Angus, M; Crawford, GM; Hamilton, L; Wade, A; Wilson, R, 2003)
"Mirtazapine is a third-generation antidepressant with a dual mode of action."2.72Intravenous mirtazapine is safe and effective in the treatment of depressed inpatients. ( Egger, C; Eichberger, G; Hinterhuber, H; Hofmann, P; Kasper, S; Konstantinidis, A; Mühlbacher, M; Nickel, M; Nimmerrichter, A; Schubert, H; Stuppaeck, C, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rizo, C1
Deshpande, A1
Ing, A1
Seeman, N1
Wade, A1
Crawford, GM1
Angus, M1
Wilson, R1
Hamilton, L1
Wingen, M1
Bothmer, J1
Langer, S1
Ramaekers, JG2
Mühlbacher, M1
Konstantinidis, A1
Kasper, S1
Eichberger, G1
Hinterhuber, H1
Hofmann, P1
Nimmerrichter, A1
Schubert, H1
Egger, C1
Nickel, M1
Stuppaeck, C1
Swijgman, HF1
O'Hanlon, JF1

Trials

4 trials available for mianserin and Fatigue

ArticleYear
A randomized, double-blind, 24-week study comparing the efficacy and tolerability of mirtazapine and paroxetine in depressed patients in primary care.
    International clinical psychopharmacology, 2003, Volume: 18, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Antidepress

2003
Actual driving performance and psychomotor function in healthy subjects after acute and subchronic treatment with escitalopram, mirtazapine, and placebo: a crossover trial.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:4

    Topics: Adult; Affect; Antidepressive Agents, Tricyclic; Automobile Driving; Circadian Rhythm; Citalopram; C

2005
Intravenous mirtazapine is safe and effective in the treatment of depressed inpatients.
    Neuropsychobiology, 2006, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Fatigue; Fema

2006
Effects of moclobemide and mianserin on highway driving, psychometric performance and subjective parameters, relative to placebo.
    Psychopharmacology, 1992, Volume: 106 Suppl

    Topics: Adult; Attention; Automobile Driving; Benzamides; Double-Blind Method; Fatigue; Female; Flicker Fusi

1992

Other Studies

1 other study available for mianserin and Fatigue

ArticleYear
A rapid, Web-based method for obtaining patient views on effects and side-effects of antidepressants.
    Journal of affective disorders, 2011, Volume: 130, Issue:1-2

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanols; Data Col

2011