metronidazole has been researched along with Ileus in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Ileus: A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Elekonawo, FMK | 1 |
van der Meeren, MMD | 1 |
Simkens, GA | 1 |
de Wilt, JHW | 1 |
de Hingh, IH | 1 |
Bremers, AJA | 1 |
Carreiro, FT | 1 |
Coelho, SC | 1 |
Horta, AB | 1 |
Sá, J | 1 |
Vaishnavi, C | 1 |
1 review available for metronidazole and Ileus
Article | Year |
---|---|
Clostridium difficile infection: clinical spectrum and approach to management.
Topics: Aminoglycosides; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Dietary Su | 2011 |
2 other studies available for metronidazole and Ileus
Article | Year |
---|---|
Comparison of 2 Perioperative Management Protocols and Their Influence on Postoperative Recovery after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Standard Parenteral Nutrition, Selective Bowel Decontamination and Suprapubic Cathe
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefazolin; Ceftriaxone; Cytoreduction Surgical | 2019 |
Adynamic ileus and diarrhoea: a rare adverse effect of antidepressants.
Topics: Aged; Anti-Bacterial Agents; Antidepressive Agents; Colonoscopy; Diarrhea; Female; Humans; Iatrogeni | 2015 |