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metronidazole and Ileus

metronidazole has been researched along with Ileus in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Ileus: A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elekonawo, FMK1
van der Meeren, MMD1
Simkens, GA1
de Wilt, JHW1
de Hingh, IH1
Bremers, AJA1
Carreiro, FT1
Coelho, SC1
Horta, AB1
Sá, J1
Vaishnavi, C1

Reviews

1 review available for metronidazole and Ileus

ArticleYear
Clostridium difficile infection: clinical spectrum and approach to management.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2011, Volume: 30, Issue:6

    Topics: Aminoglycosides; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Dietary Su

2011

Other Studies

2 other studies available for metronidazole and Ileus

ArticleYear
Comparison of 2 Perioperative Management Protocols and Their Influence on Postoperative Recovery after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Standard Parenteral Nutrition, Selective Bowel Decontamination and Suprapubic Cathe
    Digestive surgery, 2019, Volume: 36, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefazolin; Ceftriaxone; Cytoreduction Surgical

2019
Adynamic ileus and diarrhoea: a rare adverse effect of antidepressants.
    BMJ case reports, 2015, May-29, Volume: 2015

    Topics: Aged; Anti-Bacterial Agents; Antidepressive Agents; Colonoscopy; Diarrhea; Female; Humans; Iatrogeni

2015