metronidazole has been researched along with Cyst in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole treatment increased the brain spiramycin area under the concentration-time curve from 0 h to ∞ (AUC(0-∞)) by 67% without affecting its plasma disposition." | 5.38 | Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. ( Ambu, S; Chew, WK; Mak, JW; Segarra, I, 2012) |
| " The influence of clindamycin plus metronidazole therapy (group I) and cephazolin therapy (group II) on fibrinogen concentration, level of bFGF and fibrin viscosity was studied in women diagnosed with nonmalignant myomas and cysts." | 3.77 | Influence of antibiotic therapy on the level of selected angiogenic factors in patients with benign gynecologic tumors--preliminary report. ( Kaplińska, K; Lazarenkow, A; Michalska, M; Mirowski, M; Nawrot-Modranka, J; Palatyńska-Ulatowska, A; Palatyński, A, 2011) |
| "Giardiasis is an intestinal protozoal disease caused by Giardia lamblia (G." | 1.91 | The impact of L-citrulline on murine intestinal cell integrity, immune response, and arginine metabolism in the face of Giardia lamblia infection. ( Ibrahim, FM; Nasef, NA; Saad, AE; Zoghroban, HS, 2023) |
| "Metronidazole treatment increased the brain spiramycin area under the concentration-time curve from 0 h to ∞ (AUC(0-∞)) by 67% without affecting its plasma disposition." | 1.38 | Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. ( Ambu, S; Chew, WK; Mak, JW; Segarra, I, 2012) |
| "polecki cysts in the stool." | 1.26 | Successful treatment of symptomatic Entamoeba polecki infection. ( Salaki, JS; Shirey, JL; Strickland, GT, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zoghroban, HS | 1 |
| Ibrahim, FM | 1 |
| Nasef, NA | 1 |
| Saad, AE | 1 |
| Sayma, M | 1 |
| Walters, HR | 1 |
| Hesford, C | 1 |
| Tariq, Z | 1 |
| Nakhosteen, A | 1 |
| Michalska, M | 1 |
| Palatyńska-Ulatowska, A | 1 |
| Palatyński, A | 1 |
| Mirowski, M | 1 |
| Kaplińska, K | 1 |
| Nawrot-Modranka, J | 1 |
| Lazarenkow, A | 1 |
| Chew, WK | 1 |
| Segarra, I | 1 |
| Ambu, S | 1 |
| Mak, JW | 1 |
| Chung, DA | 1 |
| Salaki, JS | 1 |
| Shirey, JL | 1 |
| Strickland, GT | 1 |
6 other studies available for metronidazole and Cyst
| Article | Year |
|---|---|
The impact of L-citrulline on murine intestinal cell integrity, immune response, and arginine metabolism in the face of Giardia lamblia infection.
Topics: Animals; Arginase; Arginine; Citrulline; Cysts; Giardia; Giardia lamblia; Giardiasis; Immunity; Male | 2023 |
Rapidly enlarging, giant hepatic cyst growing pseudomonas.
Topics: Aged; Anti-Bacterial Agents; Cardiac Output, Low; Cysts; Drainage; Dyspnea; Female; Humans; Liver Di | 2019 |
Influence of antibiotic therapy on the level of selected angiogenic factors in patients with benign gynecologic tumors--preliminary report.
Topics: Adult; Aged; Angiogenic Proteins; Anti-Bacterial Agents; Cefazolin; Cysts; Female; Fibrin; Fibrinoge | 2011 |
Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis.
Topics: Animals; Antiprotozoal Agents; Area Under Curve; Brain; Chromatography, High Pressure Liquid; Cysts; | 2012 |
Infected lung cysts.
Topics: Adult; Bacterial Infections; Clindamycin; Cysts; Drug Therapy, Combination; Female; Humans; Lung Dis | 1999 |
Successful treatment of symptomatic Entamoeba polecki infection.
Topics: Acetanilides; Adult; Amebiasis; Cysts; Entamoeba; Entamoebiasis; Furans; Humans; Male; Metronidazole | 1979 |