Page last updated: 2024-10-19

melatonin and Uveitis

melatonin has been researched along with Uveitis in 10 studies

Uveitis: Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Melatonin regulates autoimmune T cells by restraining effector T cells and facilitating Treg generation, indicating that melatonin could be a hopeful treatment alternative for autoimmune uveitis."8.12Melatonin, an endogenous hormone, modulates Th17 cells via the reactive-oxygen species/TXNIP/HIF-1α axis to alleviate autoimmune uveitis. ( Chen, G; Chen, Q; Chen, X; Chen, Y; Hu, Y; Huang, H; Huang, J; Li, Z; Liang, D; Su, W; Xie, Y; Zhu, W, 2022)
"These results indicate that treatment with melatonin, starting after the onset of uveitis, attenuated ocular inflammation induced by LPS in the Syrian hamster and support the use of melatonin as a therapeutic resource for uveitis treatment."7.80Treatment with melatonin after onset of experimental uveitis attenuates ocular inflammation. ( Chianelli, M; Domínguez Rubio, AP; Dorfman, D; Fernandez, DC; Franchi, AM; Rosenstein, RE; Sáenz, DA; Sande, PH; Silberman, DM, 2014)
"To observe ultrastructural changes and leptin expression in the guinea pig eye during experimental uveitis (EU) and the effects of vitamin E, melatonin and aprotinin on leptin expression."7.73Effects of intraperitoneal vitamin E, melatonin and aprotinin on leptin expression in the guinea pig eye during experimental uveitis. ( Alagöz, G; Celebi, S; Colakoğlu, N; Kükner, A; Kükner, AS; Serin, D, 2006)
"The treatment with melatonin significantly decreased clinical signs and prevented the reduction in IOP induced by LPS."5.38Therapeutic benefit of melatonin in experimental feline uveitis. ( Aba, MA; Del Sole, MJ; Fernandez, DC; Rosenstein, RE; Sande, PH; Sarmiento, MI, 2012)
"Uveitis is a common ophthalmic disorder that can be induced in hamsters by a single intravitreal injection of bacterial lipopolysaccharide (LPS)."5.35Therapeutic effect of melatonin in experimental uveitis. ( Aisemberg, J; Aldana Marcos, HJ; Chianelli, MS; Fernandez, DC; Rosenstein, RE; Sáenz, DA; Sande, PH; Silberman, DM, 2008)
"Melatonin regulates autoimmune T cells by restraining effector T cells and facilitating Treg generation, indicating that melatonin could be a hopeful treatment alternative for autoimmune uveitis."4.12Melatonin, an endogenous hormone, modulates Th17 cells via the reactive-oxygen species/TXNIP/HIF-1α axis to alleviate autoimmune uveitis. ( Chen, G; Chen, Q; Chen, X; Chen, Y; Hu, Y; Huang, H; Huang, J; Li, Z; Liang, D; Su, W; Xie, Y; Zhu, W, 2022)
"These results indicate that treatment with melatonin, starting after the onset of uveitis, attenuated ocular inflammation induced by LPS in the Syrian hamster and support the use of melatonin as a therapeutic resource for uveitis treatment."3.80Treatment with melatonin after onset of experimental uveitis attenuates ocular inflammation. ( Chianelli, M; Domínguez Rubio, AP; Dorfman, D; Fernandez, DC; Franchi, AM; Rosenstein, RE; Sáenz, DA; Sande, PH; Silberman, DM, 2014)
"To observe ultrastructural changes and leptin expression in the guinea pig eye during experimental uveitis (EU) and the effects of vitamin E, melatonin and aprotinin on leptin expression."3.73Effects of intraperitoneal vitamin E, melatonin and aprotinin on leptin expression in the guinea pig eye during experimental uveitis. ( Alagöz, G; Celebi, S; Colakoğlu, N; Kükner, A; Kükner, AS; Serin, D, 2006)
"Melatonin is an efficient antioxidant and antinitridergic, and has the ability to reduce prostaglandin and tumor necrosis factor levels both in the retina and optic nerve."2.55Melatonin as a Therapeutic Resource for Inflammatory Visual Diseases. ( Aranda, ML; Dieguez, H; Dorfman, D; Fleitas, MFG; Iaquinandi, A; Rosenstein, RE; Sande, PH, 2017)
"The treatment with melatonin significantly decreased clinical signs and prevented the reduction in IOP induced by LPS."1.38Therapeutic benefit of melatonin in experimental feline uveitis. ( Aba, MA; Del Sole, MJ; Fernandez, DC; Rosenstein, RE; Sande, PH; Sarmiento, MI, 2012)
"Uveitis is a common ophthalmic disorder that can be induced in hamsters by a single intravitreal injection of bacterial lipopolysaccharide (LPS)."1.35Therapeutic effect of melatonin in experimental uveitis. ( Aisemberg, J; Aldana Marcos, HJ; Chianelli, MS; Fernandez, DC; Rosenstein, RE; Sáenz, DA; Sande, PH; Silberman, DM, 2008)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Huang, J1
Li, Z2
Hu, Y1
Xie, Y1
Huang, H1
Chen, Q1
Chen, G1
Zhu, W1
Chen, Y1
Su, W1
Chen, X1
Liang, D1
Scuderi, L1
Davinelli, S1
Iodice, CM1
Bartollino, S1
Scapagnini, G1
Costagliola, C1
Scuderi, G1
Sande, PH4
Dorfman, D2
Fernandez, DC3
Chianelli, M1
Domínguez Rubio, AP1
Franchi, AM1
Silberman, DM2
Rosenstein, RE5
Sáenz, DA2
Aranda, ML1
Fleitas, MFG1
Dieguez, H1
Iaquinandi, A1
Aldana Marcos, HJ1
Chianelli, MS1
Aisemberg, J1
Pandi-Perumal, SR1
Srinivasan, V1
Spence, DW1
Brown, GM1
Cardinali, DP1
Del Sole, MJ1
Sarmiento, MI1
Aba, MA1
Kükner, A1
Colakoğlu, N1
Serin, D1
Alagöz, G1
Celebi, S1
Kükner, AS1
Wollmann, HA1
Pleyer, U1
Friedel, S1
Zierhut, M1
Thiel, HJ1
Gupta, D1
Touitou, Y1
Le Hoang, P1
Claustrat, B1
Attye, T1
Auzeby, A1
Brun, J1
Bogdan, A1
Touitou, C1

Reviews

3 reviews available for melatonin and Uveitis

ArticleYear
Melatonin: Implications for Ocular Disease and Therapeutic Potential.
    Current pharmaceutical design, 2019, Volume: 25, Issue:39

    Topics: Aging; Eye; Free Radicals; Glaucoma; Humans; Melatonin; Uveitis

2019
Melatonin as a Therapeutic Resource for Inflammatory Visual Diseases.
    Current neuropharmacology, 2017, Volume: 15, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Melatonin; Optic Neuritis; Uveitis

2017
Melatonin as a therapeutic tool in ophthalmology: implications for glaucoma and uveitis.
    Journal of pineal research, 2010, Volume: 49, Issue:1

    Topics: Animals; Glaucoma; Humans; Melatonin; Neuroprotective Agents; Ophthalmology; Receptors, Melatonin; U

2010

Other Studies

7 other studies available for melatonin and Uveitis

ArticleYear
Melatonin, an endogenous hormone, modulates Th17 cells via the reactive-oxygen species/TXNIP/HIF-1α axis to alleviate autoimmune uveitis.
    Journal of neuroinflammation, 2022, May-27, Volume: 19, Issue:1

    Topics: Animals; Autoimmune Diseases; Carrier Proteins; Melatonin; Mice; Oxygen; Reactive Oxygen Species; Th

2022
Treatment with melatonin after onset of experimental uveitis attenuates ocular inflammation.
    British journal of pharmacology, 2014, Volume: 171, Issue:24

    Topics: Animals; Antioxidants; Aqueous Humor; Cricetinae; Dinoprost; Dinoprostone; Disease Models, Animal; E

2014
Therapeutic effect of melatonin in experimental uveitis.
    The American journal of pathology, 2008, Volume: 173, Issue:6

    Topics: Animals; Blood-Retinal Barrier; Cricetinae; Cricetulus; Disease Models, Animal; Electroretinography;

2008
Therapeutic benefit of melatonin in experimental feline uveitis.
    Journal of pineal research, 2012, Volume: 52, Issue:1

    Topics: Analysis of Variance; Animals; Cats; Electroretinography; Histocytochemistry; Intraocular Pressure;

2012
Effects of intraperitoneal vitamin E, melatonin and aprotinin on leptin expression in the guinea pig eye during experimental uveitis.
    Acta ophthalmologica Scandinavica, 2006, Volume: 84, Issue:1

    Topics: Animals; Antioxidants; Aprotinin; Choroid; Disease Models, Animal; Free Radical Scavengers; Guinea P

2006
Neuroendocrine alterations in uveitis patients.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1994, Volume: 232, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Endocrine Glands; Female; Humans; Immune System; Interleukin-2; Male

1994
Decreased nocturnal plasma melatonin peak in patients with a functional alteration of the retina in relation with uveitis.
    Neuroscience letters, 1986, Sep-25, Volume: 70, Issue:1

    Topics: Adolescent; Adult; Female; Humans; Male; Melatonin; Middle Aged; Pineal Gland; Radioimmunoassay; Ret

1986