melatonin has been researched along with Glioma in 25 studies
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin, an indolamine mostly synthesized in the pineal gland, exerts the anti-cancer effect by various mechanisms in glioma cells." | 7.85 | Melatonin inhibits proliferation and invasion via repression of miRNA-155 in glioma cells. ( Chen, Y; Gu, J; Ji, C; Lei, Z; Li, X; Liu, Y; Lu, Z; Wang, L; Zhang, HT, 2017) |
| "Melatonin, a well-known antioxidant, has been shown to possess anti-invasive properties for glioma." | 7.81 | Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia. ( Cao, CJ; Dai, LM; Huang, XD; Li, ZQ; Wang, ZF; Xu, CS, 2015) |
| "Pretreatment with melatonin effectively promoted Nrf2 activation and reversed the METH-induced NF-κB response." | 5.42 | Melatonin Protects Methamphetamine-Induced Neuroinflammation Through NF-κB and Nrf2 Pathways in Glioma Cell Line. ( Govitrapong, P; Jumnongprakhon, P; Pinkaew, D; Tocharus, C; Tocharus, J, 2015) |
| "Melatonin is an indolamine mostly produced in the pineal gland, soluble in water, and highly lipophilic, which allows it to readily cross the blood-brain barrier." | 5.33 | Intracellular signaling pathways involved in the cell growth inhibition of glioma cells by melatonin. ( Antolín, I; Carrera-Gonzalez, P; García-Santos, G; Herrera, F; Martín, V; Rodriguez, C; Rodriguez-Blanco, J, 2006) |
| "Melatonin, an indolamine mostly synthesized in the pineal gland, exerts the anti-cancer effect by various mechanisms in glioma cells." | 3.85 | Melatonin inhibits proliferation and invasion via repression of miRNA-155 in glioma cells. ( Chen, Y; Gu, J; Ji, C; Lei, Z; Li, X; Liu, Y; Lu, Z; Wang, L; Zhang, HT, 2017) |
| "Melatonin, a well-known antioxidant, has been shown to possess anti-invasive properties for glioma." | 3.81 | Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia. ( Cao, CJ; Dai, LM; Huang, XD; Li, ZQ; Wang, ZF; Xu, CS, 2015) |
| "Confirmed lesions included pineocytoma WHO grade I (60." | 3.01 | Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification. ( De Domenico, P; Gagliardi, F; Garbin, E; Mortini, P; Snider, S, 2023) |
| "Gliomas, the most common primary brain tumors in adults, are classified into four malignancy grades according to morphological features." | 1.43 | Melatonergic system-based two-gene index is prognostic in human gliomas. ( Carvalho-Sousa, CE; Fernandes, PA; Kinker, GS; Marie, SK; Markus, RP; Muxel, SM; Oba-Shinjo, SM, 2016) |
| "Pretreatment with melatonin effectively promoted Nrf2 activation and reversed the METH-induced NF-κB response." | 1.42 | Melatonin Protects Methamphetamine-Induced Neuroinflammation Through NF-κB and Nrf2 Pathways in Glioma Cell Line. ( Govitrapong, P; Jumnongprakhon, P; Pinkaew, D; Tocharus, C; Tocharus, J, 2015) |
| "Melatonin not only plays an important role in regulating circadian rhythms, but is also involved in antioxidative defense and immunomodulation." | 1.39 | Serotoninergic and melatoninergic systems are expressed in mouse embryonic fibroblasts NIH3T3 cells. ( Liu, YJ; Meng, FT; Wu, L; Zhou, JN, 2013) |
| "Melatonin is an indolamine mostly produced in the pineal gland, soluble in water, and highly lipophilic, which allows it to readily cross the blood-brain barrier." | 1.33 | Intracellular signaling pathways involved in the cell growth inhibition of glioma cells by melatonin. ( Antolín, I; Carrera-Gonzalez, P; García-Santos, G; Herrera, F; Martín, V; Rodriguez, C; Rodriguez-Blanco, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (20.00) | 29.6817 |
| 2010's | 14 (56.00) | 24.3611 |
| 2020's | 5 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, W | 3 |
| Song, G | 3 |
| Gagliardi, F | 1 |
| De Domenico, P | 1 |
| Garbin, E | 1 |
| Snider, S | 1 |
| Mortini, P | 1 |
| Anderson, G | 2 |
| Hartung, EE | 1 |
| Mukhtar, SZ | 1 |
| Shah, SM | 1 |
| Niles, LP | 2 |
| Wang, C | 1 |
| Zhao, Z | 1 |
| Qi, Q | 1 |
| Wang, J | 3 |
| Kong, Y | 1 |
| Feng, Z | 1 |
| Chen, A | 1 |
| Li, W | 1 |
| Zhang, Q | 1 |
| Huang, B | 1 |
| Li, X | 2 |
| Gu, J | 1 |
| Lu, Z | 1 |
| Ji, C | 1 |
| Chen, Y | 1 |
| Liu, Y | 1 |
| Lei, Z | 1 |
| Wang, L | 1 |
| Zhang, HT | 1 |
| Ma, H | 1 |
| Wang, Z | 1 |
| Hu, L | 1 |
| Zhang, S | 1 |
| Zhao, C | 1 |
| Yang, H | 1 |
| Wang, H | 1 |
| Fang, Z | 1 |
| Wu, L | 2 |
| Chen, X | 1 |
| Franco, DG | 1 |
| Moretti, IF | 1 |
| Marie, SKN | 1 |
| Maitra, S | 1 |
| Bhattacharya, D | 1 |
| Das, S | 1 |
| Bhattacharya, S | 1 |
| Liu, YJ | 1 |
| Meng, FT | 1 |
| Zhou, JN | 1 |
| Martín, V | 4 |
| Sanchez-Sanchez, AM | 1 |
| Puente-Moncada, N | 1 |
| Gomez-Lobo, M | 1 |
| Alvarez-Vega, MA | 1 |
| Antolín, I | 4 |
| Rodriguez, C | 4 |
| Xu, CS | 1 |
| Wang, ZF | 1 |
| Huang, XD | 1 |
| Dai, LM | 1 |
| Cao, CJ | 1 |
| Li, ZQ | 1 |
| Jumnongprakhon, P | 2 |
| Govitrapong, P | 2 |
| Tocharus, C | 2 |
| Pinkaew, D | 1 |
| Tocharus, J | 2 |
| Kinker, GS | 1 |
| Oba-Shinjo, SM | 1 |
| Carvalho-Sousa, CE | 1 |
| Muxel, SM | 1 |
| Marie, SK | 1 |
| Markus, RP | 1 |
| Fernandes, PA | 1 |
| Beischlag, TV | 1 |
| Mazzoccoli, G | 1 |
| Tungkum, W | 1 |
| García-Santos, G | 3 |
| Rodriguez-Blanco, J | 3 |
| Casado-Zapico, S | 1 |
| Sanchez-Sanchez, A | 1 |
| Medina, M | 2 |
| González, A | 2 |
| Martínez-Campa, C | 2 |
| Mediavilla, MD | 2 |
| Alonso-González, C | 2 |
| Alvarez-García, V | 1 |
| Sánchez-Barceló, EJ | 2 |
| Cos, S | 2 |
| Hao, H | 1 |
| Yao, L | 1 |
| Zhang, X | 1 |
| Zhao, S | 1 |
| Ling, EA | 1 |
| Hao, A | 1 |
| Li, G | 1 |
| Herrera, F | 2 |
| Carrera-Gonzalez, P | 1 |
| Wion, D | 1 |
| Berger, F | 1 |
| Wion-Barbot, N | 1 |
| Arenander, AT | 1 |
| de Vellis, J | 1 |
| Armstrong, KJ | 1 |
3 reviews available for melatonin and Glioma
| Article | Year |
|---|---|
Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Topics: Brain Neoplasms; Glioma; Humans; Melatonin; Neoplasms, Germ Cell and Embryonal; Pineal Gland; Pineal | 2023 |
Melatonin and its anti-glioma functions: a comprehensive review.
Topics: Animals; Antineoplastic Agents; Antioxidants; Brain Neoplasms; Glioma; Humans; Melatonin; Signal Tra | 2019 |
Glioma: Tryptophan Catabolite and Melatoninergic Pathways Link microRNA, 14-3- 3, Chromosome 4q35, Epigenetic Processes and other Glioma Biochemical Changes.
Topics: Animals; Chromosomes, Human, Pair 4; Epigenesis, Genetic; Glioma; Humans; Inflammation; Melatonin; M | 2016 |
22 other studies available for melatonin and Glioma
| Article | Year |
|---|---|
A comprehensive analysis-based study of triphenyl phosphate-environmental explanation of glioma progression.
Topics: Flame Retardants; Glioma; Humans; Liver Neoplasms; Male; Melatonin | 2022 |
A comprehensive analysis-based study of triphenyl phosphate-environmental explanation of glioma progression.
Topics: Flame Retardants; Glioma; Humans; Liver Neoplasms; Male; Melatonin | 2022 |
A comprehensive analysis-based study of triphenyl phosphate-environmental explanation of glioma progression.
Topics: Flame Retardants; Glioma; Humans; Liver Neoplasms; Male; Melatonin | 2022 |
A comprehensive analysis-based study of triphenyl phosphate-environmental explanation of glioma progression.
Topics: Flame Retardants; Glioma; Humans; Liver Neoplasms; Male; Melatonin | 2022 |
The effects of melatonin on signaling pathways and molecules involved in glioma: Melatonin and glioblastoma: pathophysiology and treatment.
Topics: Glioblastoma; Glioma; Humans; Melatonin; Signal Transduction | 2020 |
5-Azacytidine upregulates melatonin MT
Topics: Animals; Azacitidine; Cell Line; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression; Gene Expres | 2020 |
miR-6858 plays a key role in the process of melatonin inhibition of the malignant biological behavior of glioma.
Topics: Animals; Antioxidants; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Re | 2021 |
Melatonin inhibits proliferation and invasion via repression of miRNA-155 in glioma cells.
Topics: Antioxidants; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioma; Humans; Melatonin; Micr | 2017 |
The melatonin-MT1 receptor axis modulates tumor growth in PTEN-mutated gliomas.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Female; Glioma; Humans; Mal | 2018 |
Mitochondria Transcription Factor A: A Putative Target for the Effect of Melatonin on U87MG Malignant Glioma Cell Line.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; DNA Replica | 2018 |
Serotoninergic and melatoninergic systems are expressed in mouse embryonic fibroblasts NIH3T3 cells.
Topics: Animals; Apolipoproteins E; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Fibroblasts; Gene Express | 2013 |
Involvement of autophagy in melatonin-induced cytotoxicity in glioma-initiating cells.
Topics: Autophagy; Base Sequence; Brain Neoplasms; Flow Cytometry; Glioma; Humans; Melatonin; Microscopy, El | 2014 |
Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia.
Topics: Cell Hypoxia; Cell Line, Tumor; Cell Movement; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Gen | 2015 |
Melatonin Protects Methamphetamine-Induced Neuroinflammation Through NF-κB and Nrf2 Pathways in Glioma Cell Line.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Glioma; Melatonin; Methamphetamine; NF- | 2015 |
Melatonergic system-based two-gene index is prognostic in human gliomas.
Topics: Acetylserotonin O-Methyltransferase; Animals; Brain Neoplasms; Cell Line, Tumor; Cytochrome P-450 CY | 2016 |
Melatonin suppresses methamphetamine-triggered endoplasmic reticulum stress in C6 cells glioma cell lines.
Topics: Activating Transcription Factor 6; Animals; Caspase 12; Cell Line, Tumor; Cell Survival; eIF-2 Kinas | 2017 |
Melatonin sensitizes human malignant glioma cells against TRAIL-induced cell death.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Survival; Glioma; | 2010 |
Inhibitory effects of melatonin on sulfatase and 17beta-hydroxysteroid dehydrogenase activity and expression in glioma cells.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Antioxidants; Cell Line, Tumor; Glioma; Melatonin; Rats; | 2010 |
Melatonin suppresses migration and invasion via inhibition of oxidative stress pathway in glioma cells.
Topics: Cell Line, Tumor; Cell Movement; Cell Survival; Free Radicals; Glioma; Humans; Melatonin; NF-kappa B | 2012 |
Intracellular signaling pathways involved in the cell growth inhibition of glioma cells by melatonin.
Topics: Animals; Antioxidants; Brain Neoplasms; Cell Cycle; Cell Proliferation; Free Radicals; Glioma; Melat | 2006 |
Glioma, melatonin, and radiotherapy.
Topics: Animals; Brain Neoplasms; Glioma; Melatonin; Pineal Gland; Rats | 2006 |
Inhibitory effects of pharmacological doses of melatonin on aromatase activity and expression in rat glioma cells.
Topics: Animals; Aromatase; Down-Regulation; Enzyme Inhibitors; Estrogens; Gene Expression Regulation, Enzym | 2007 |
Involvement of protein kinase C in melatonin's oncostatic effect in C6 glioma cells.
Topics: Animals; Cell Line, Tumor; Enzyme Activation; Glioma; Melatonin; Phorbol Esters; Protein Kinase C; R | 2007 |
Glial-released proteins in clonal cultures and their modulation by hydrocortisone.
Topics: Animals; Bucladesine; Cell Line; Estradiol; Glioma; Hydrocortisone; Isoproterenol; Melatonin; Molecu | 1980 |
Induction of GDNF mRNA expression by melatonin in rat C6 glioma cells.
Topics: Animals; Antioxidants; Free Radical Scavengers; Glial Cell Line-Derived Neurotrophic Factor; Glioma; | 2002 |