Page last updated: 2024-10-19

melatonin and Amentia

melatonin has been researched along with Amentia in 43 studies

Research Excerpts

ExcerptRelevanceReference
"Forty-four participants with DSM-IV diagnoses of dementia with sleep disturbance were selected for a seven week randomised double blind cross over trial of slow release melatonin 6 mg versus placebo."9.10Double blind randomised placebo controlled trial of low dose melatonin for sleep disorders in dementia. ( Blizard, R; Kennell-Webb, S; Raven, P; Serfaty, M; Warner, J, 2002)
"The purpose of this study was to evaluate the effects of bright light therapy combined with melatonin on motor restless behaviour in dementia."9.09Bright light therapy and melatonin in motor restless behaviour in dementia: a placebo-controlled study. ( Cats, Q; Haffmans, PM; Lucius, SA; Sival, RC; van Gelder, L, 2001)
"The current review aims to examine melatonin therapy for both sleep disturbances and cognitive function in dementia."8.91Melatonin for sleep disorders and cognition in dementia: a meta-analysis of randomized controlled trials. ( Chen, SD; Dammer, EB; Li, CB; Wang, G; Wang, LL; Xu, G; Xu, J, 2015)
" All papers on melatonin treatment in dementia were retrieved."8.86Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review. ( de Jonghe, A; de Rooij, SE; Korevaar, JC; van Munster, BC, 2010)
" This study explored the association between clinical markers and 1) dim light melatonin onset (DLMO) time and 2) phase angle derived from sleep midpoint, in older adults with varying dementia risks."8.31Actigraphic and melatonin alignment in older adults with varying dementia risk. ( Gordon, CJ; Hickie, I; Hoyos, CM; Lewis, SJ; Menczel Schrire, Z; Murray, J; Naismith, SL; Palmer, JR; Pye, JE; Rogers, NL; Terpening, Z, 2023)
"The present work aimed to investigate the induction of circadian rhythm dysfunction and dementia upon chronic exposure to light-light and its reversal by melatonin in Wistar rats."8.12Chronic Light-Distorted Glutamate-Cortisol Signaling, Behavioral and Histological Markers, and Induced Oxidative Stress and Dementia: An Amelioration by Melatonin. ( Aljabali, AAA; Chellappan, DK; Dua, K; Goyal, R; Sarena, P; Sharma, A; Taliyan, R; Tambuwala, MM; Urmera, MT, 2022)
"A recent study in the JAMA described the effects of long-term daily treatment with whole-day bright light in elderly patients with dementia, with or without the addition of melatonin (2."7.74[Symptomatic treatment in patients with dementia: light, but not melatonin, is probably worthwhile]. ( van Marum, RJ, 2008)
"The daily rhythm in serum melatonin levels was measured in patients with dementia of the degenerate type (Alzheimer's disease, Pick's disease and senile dementia of the Alzheimer type) by radioimmunoassay."7.69Daily rhythm of serum melatonin in patients with dementia of the degenerate type. ( Morita, Y; Ohara, K; Okamoto, N; Uchida, K, 1996)
"Melatonin levels have been shown to decline with aging."6.53Melatonin based therapies for delirium and dementia. ( Alagiakrishnan, K, 2016)
" Chronic administration of melatonin (0."5.31Possible antioxidant mechanism in melatonin reversal of aging and chronic ethanol-induced amnesia in plus-maze and passive avoidance memory tasks. ( Kulkarni, SK; Raghavendra, V, 2001)
"Forty-four participants with DSM-IV diagnoses of dementia with sleep disturbance were selected for a seven week randomised double blind cross over trial of slow release melatonin 6 mg versus placebo."5.10Double blind randomised placebo controlled trial of low dose melatonin for sleep disorders in dementia. ( Blizard, R; Kennell-Webb, S; Raven, P; Serfaty, M; Warner, J, 2002)
"The purpose of this study was to evaluate the effects of bright light therapy combined with melatonin on motor restless behaviour in dementia."5.09Bright light therapy and melatonin in motor restless behaviour in dementia: a placebo-controlled study. ( Cats, Q; Haffmans, PM; Lucius, SA; Sival, RC; van Gelder, L, 2001)
"The current review aims to examine melatonin therapy for both sleep disturbances and cognitive function in dementia."4.91Melatonin for sleep disorders and cognition in dementia: a meta-analysis of randomized controlled trials. ( Chen, SD; Dammer, EB; Li, CB; Wang, G; Wang, LL; Xu, G; Xu, J, 2015)
" All papers on melatonin treatment in dementia were retrieved."4.86Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review. ( de Jonghe, A; de Rooij, SE; Korevaar, JC; van Munster, BC, 2010)
"There are a number of studies that suggest a relationship between decline of melatonin function and the symptoms of dementia."4.83Melatonin for cognitive impairment. ( Duncan, V; Forbes, DA; Jansen, SL; Morgan, DG, 2006)
" This study explored the association between clinical markers and 1) dim light melatonin onset (DLMO) time and 2) phase angle derived from sleep midpoint, in older adults with varying dementia risks."4.31Actigraphic and melatonin alignment in older adults with varying dementia risk. ( Gordon, CJ; Hickie, I; Hoyos, CM; Lewis, SJ; Menczel Schrire, Z; Murray, J; Naismith, SL; Palmer, JR; Pye, JE; Rogers, NL; Terpening, Z, 2023)
"The present work aimed to investigate the induction of circadian rhythm dysfunction and dementia upon chronic exposure to light-light and its reversal by melatonin in Wistar rats."4.12Chronic Light-Distorted Glutamate-Cortisol Signaling, Behavioral and Histological Markers, and Induced Oxidative Stress and Dementia: An Amelioration by Melatonin. ( Aljabali, AAA; Chellappan, DK; Dua, K; Goyal, R; Sarena, P; Sharma, A; Taliyan, R; Tambuwala, MM; Urmera, MT, 2022)
" Elevated plasma homocysteine is a risk factor for atherosclerosis and Alzheimer's disease, and the marked decline in adenosyl methionine with aging leads to dysregulation of methionine metabolism and hyperhomocysteinemia."3.88 ( McCully, KS, 2018)
"A recent study in the JAMA described the effects of long-term daily treatment with whole-day bright light in elderly patients with dementia, with or without the addition of melatonin (2."3.74[Symptomatic treatment in patients with dementia: light, but not melatonin, is probably worthwhile]. ( van Marum, RJ, 2008)
"The daily rhythm in serum melatonin levels was measured in patients with dementia of the degenerate type (Alzheimer's disease, Pick's disease and senile dementia of the Alzheimer type) by radioimmunoassay."3.69Daily rhythm of serum melatonin in patients with dementia of the degenerate type. ( Morita, Y; Ohara, K; Okamoto, N; Uchida, K, 1996)
"Adult patients with a cancer diagnosis who are admitted to the palliative care unit will be randomized into a treatment or placebo group."2.82The preventative role of exogenous melatonin administration to patients with advanced cancer who are at risk of delirium: study protocol for a randomized controlled trial. ( Agar, M; Bush, SH; Currow, DC; Lacaze-Masmonteil, N; Lawlor, PG; MacDonald, AR; McNamara-Kilian, MT; Momoli, F; Tierney, S, 2016)
"Melatonin plays a major role in maintaining circadian rhythm."2.53Physiological melatonin levels in healthy older people: A systematic review. ( de Rooij, SE; Scholtens, RM; van Kempen, MF; van Munster, BC, 2016)
"Melatonin levels have been shown to decline with aging."2.53Melatonin based therapies for delirium and dementia. ( Alagiakrishnan, K, 2016)
"Circadian rhythm sleep disorders are caused by the disturbance of sleep-wake regulation in the central nervous system, disturbed input into the sensory organs, and decreased social activities."2.50[Sleep problems in dementia]. ( Oka, Y, 2014)
"The features of apoptotic dose responses typically have been evaluated over a broad dose-response continuum to differentiate apoptotic and necrotic responses."2.41Apoptosis: biphasic dose responses. ( Calabrese, EJ, 2001)
"Prevention of dementia is important, because it is a leading cause of disability in elderly people."1.91Effects of endogenous and exogenous N-acetyl-5-methoxy kynuramine on object recognition memory in male C3H mice. ( Chiba, A; Iwashita, H; Sano, M, 2023)
"Melatonin is an endogenous pleiotropic molecule which orchestrates regulatory functions and protective capacity against age-related ailments."1.48Melatonin induces mechanisms of brain resilience against neurodegeneration. ( Cardoso, BR; Corpas, R; Franciscato Cozzolino, SM; García de Frutos, P; Griñán-Ferré, C; Pallàs, M; Palomera-Ávalos, V; Porquet, D; Rodríguez-Farré, E; Sanfeliu, C, 2018)
"Treatment of circadian rhythm disorders has led to the development of a new type of agent called "chronobiotics," among which melatonin is the prototype."1.33Clinical perspectives for the use of melatonin as a chronobiotic and cytoprotective agent. ( Cardinali, DP; Furio, AM; Reyes, MP, 2005)
" Chronic administration of melatonin (0."1.31Possible antioxidant mechanism in melatonin reversal of aging and chronic ethanol-induced amnesia in plus-maze and passive avoidance memory tasks. ( Kulkarni, SK; Raghavendra, V, 2001)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.98)18.7374
1990's5 (11.63)18.2507
2000's16 (37.21)29.6817
2010's15 (34.88)24.3611
2020's4 (9.30)2.80

Authors

AuthorsStudies
Sarena, P1
Sharma, A1
Urmera, MT1
Tambuwala, MM1
Aljabali, AAA1
Chellappan, DK1
Dua, K1
Taliyan, R1
Goyal, R1
Menczel Schrire, Z3
Gordon, CJ3
Palmer, JR3
Murray, J3
Hickie, I3
Rogers, NL3
Lewis, SJ3
Terpening, Z3
Pye, JE3
Naismith, SL3
Hoyos, CM3
Iwashita, H1
Sano, M1
Chiba, A1
Iranzo, A1
Ramos, LA1
Novo, S1
Münch, M1
Schmieder, M1
Bieler, K1
Goldbach, R1
Fuhrmann, T1
Zumstein, N1
Vonmoos, P1
Scartezzini, JL1
Wirz-Justice, A1
Cajochen, C1
McCully, KS1
Corpas, R1
Griñán-Ferré, C1
Palomera-Ávalos, V1
Porquet, D1
García de Frutos, P1
Franciscato Cozzolino, SM1
Rodríguez-Farré, E1
Pallàs, M1
Sanfeliu, C1
Cardoso, BR1
Park, J1
Han, JW1
Lee, JR1
Byun, S1
Suh, SW1
Kim, T1
Yoon, IY1
Kim, KW1
Gardner, C1
Xu, J1
Wang, LL1
Dammer, EB1
Li, CB1
Xu, G1
Chen, SD1
Wang, G1
Oka, Y1
Hu, K1
Riemersma-van der Lek, RF3
Patxot, M1
Li, P1
Shea, SA1
Scheer, FA1
Van Someren, EJ2
Scholtens, RM1
van Munster, BC2
van Kempen, MF1
de Rooij, SE2
Alagiakrishnan, K1
Bush, SH1
Lacaze-Masmonteil, N1
McNamara-Kilian, MT1
MacDonald, AR1
Tierney, S1
Momoli, F1
Agar, M1
Currow, DC1
Lawlor, PG1
Pillai, JA1
Leverenz, JB1
Swaab, DF2
Twisk, J2
Hol, EM2
Hoogendijk, WJ2
van Marum, RJ1
van Someren, EW1
Arushanian, EB1
de Jonghe, A1
Korevaar, JC1
Bedrosian, TA1
Herring, KL1
Weil, ZM1
Nelson, RJ1
Serfaty, M1
Kennell-Webb, S1
Warner, J1
Blizard, R1
Raven, P1
Serrano, C1
García-Borreguero, D1
Reiter, RJ1
Tan, DX1
Pappolla, MA1
Cardinali, DP1
Furio, AM1
Reyes, MP1
Jansen, SL1
Forbes, DA1
Duncan, V1
Morgan, DG1
Wolkove, N1
Elkholy, O1
Baltzan, M1
Palayew, M1
Mahlberg, R1
Walther, S1
Touitou, Y2
Fèvre, M2
Bogdan, A2
Reinberg, A2
De Prins, J1
Beck, H2
Touitou, C2
Lagoguey, M1
Carayon, A1
Cesselin, F1
Sandyk, R1
Iacono, RP1
Uchida, K1
Okamoto, N1
Ohara, K1
Morita, Y1
McGaffigan, S1
Bliwise, DL1
Magri, F1
Locatelli, M1
Balza, G1
Molla, G1
Cuzzoni, G1
Fioravanti, M1
Solerte, SB1
Ferrari, E1
Mishima, K1
Okawa, M1
Hozumi, S1
Hishikawa, Y1
Haffmans, PM1
Sival, RC1
Lucius, SA1
Cats, Q1
van Gelder, L1
Raghavendra, V1
Kulkarni, SK1
Luboshitzky, R1
Shen-Orr, Z1
Tzischichinsky, O1
Maldonado, M1
Herer, P1
Lavie, P1
Calabrese, EJ1
Maurizi, CP1
Souêtre, E1
Salvati, E1
Krebs, B1
Belugou, JL1
Darcourt, G1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Placebo-controlled Trial Evaluating the Effect of Melatonin on Sleep Quality in Patients With Dementia[NCT03066518]Phase 440 participants (Actual)Interventional2016-01-15Completed
Multicenter Randomized Controlled Trial of the Efficacy of Melatonin in the Prophylaxis of SARS-coronavirus-2 Infection Among High Risk Contacts.[NCT04353128]Phase 2/Phase 3450 participants (Actual)Interventional2020-04-20Completed
The Preventative Role of Exogenous Melatonin Administration in Patients With Advanced Cancer Who Are at Risk of Delirium: a Feasibility Study Prior to a Larger Randomized Controlled Trial[NCT02200172]Phase 260 participants (Actual)Interventional2014-12-31Completed
Light Therapy in Parkinson's Disease: a Prospective, Observational Study[NCT06129942]50 participants (Anticipated)Interventional2021-09-01Recruiting
Dynamic Light Application to Prevent ICU Acquired Delirium[NCT01274819]1,000 participants (Actual)Interventional2011-07-31Completed
Exploratory Study of Melatonin Induced Sleep Regularization in Severe Brain Injury[NCT02732288]1 participants (Actual)Interventional2016-05-31Terminated (stopped due to Interrupted by Covid-19)
Prevention of Delirium in Inpatients Utilizing Melatonin[NCT02654314]Phase 3277 participants (Actual)Interventional2016-07-31Terminated (stopped due to Lack of resources to complete the study. Descriptive statistics for the outcome measures collected are provided.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Days Utilizing Restraints

Days utilizing restraints is defined as the number of days restraints were applied because of delirium in the first 14 days of hospitalization. (NCT02654314)
Timeframe: length of hospitalization, not to exceed 14 days

Interventiondays (Median)
Melatonin0
Cellulose Microcrystylline0

Delirium

Delirium is defined by the Short Form Confusion Assessment Method (CAM). There must be inattention and either an acute or fluctuating course plus either disorganized thinking or an altered level of consciousness to be diagnosed with delirium. Presented is a count of individuals with reported delirium during hospitalization. (NCT02654314)
Timeframe: length of hospitalization, not to exceed 14 days

InterventionParticipants (Count of Participants)
Melatonin2
Cellulose Microcrystylline8

Length of Hospital Stay

Length of stay is defined as the total time hospitalized for the acute illness (in days). (NCT02654314)
Timeframe: from day of admission to completion of acute care, not to exceed 30 days

Interventiondays (Mean)
Melatonin4.58
Cellulose Microcrystylline4.71

Number of Delirium Anti-psychotic Drug Doses Utilized for Delirium During the First 14 Days of Hospitalization.

Number of delirium anti-psychotic drug doses given for symptoms of delirium. Presented are the number of doses per days of hospitalization. (NCT02654314)
Timeframe: length of hospitalization, not to exceed 14 days

Interventionnumber of doses per days of hospitalizat (Median)
Melatonin0
Cellulose Microcrystylline0

Reviews

15 reviews available for melatonin and Amentia

ArticleYear
The Isolated Form of Rapid Eye Movement Sleep Behavior Disorder: The Upcoming Challenges.
    Sleep medicine clinics, 2021, Volume: 16, Issue:2

    Topics: Clonazepam; Dementia; Diagnostic Tests, Routine; Humans; Melatonin; Parkinson Disease; REM Sleep Beh

2021
Melatonin for sleep disorders and cognition in dementia: a meta-analysis of randomized controlled trials.
    American journal of Alzheimer's disease and other dementias, 2015, Volume: 30, Issue:5

    Topics: Alzheimer Disease; Central Nervous System Depressants; Cognition; Cognition Disorders; Dementia; Dem

2015
[Sleep problems in dementia].
    Rinsho shinkeigaku = Clinical neurology, 2014, Volume: 54, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Chronobiology Disorders; Circadian Rhythm; Dementia; Humans; Melaton

2014
Physiological melatonin levels in healthy older people: A systematic review.
    Journal of psychosomatic research, 2016, Volume: 86

    Topics: Aged; Aged, 80 and over; Aging; Circadian Rhythm; Dementia; Dietary Supplements; Female; Health Stat

2016
Melatonin based therapies for delirium and dementia.
    Discovery medicine, 2016, Volume: 21, Issue:117

    Topics: Aged; Animals; Antipsychotic Agents; Benzodiazepines; Chronobiology Phenomena; Clinical Trials as To

2016
Sleep and Neurodegeneration: A Critical Appraisal.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Alzheimer Disease; Dementia; Humans; Lewy Body Disease; Melatonin; Multiple System Atrophy; Neurodeg

2017
[A hormonal drug melatonin in the treatment of cognitive function disorders in parkinsonism].
    Eksperimental'naia i klinicheskaia farmakologiia, 2010, Volume: 73, Issue:3

    Topics: Cognition Disorders; Corpus Striatum; Dementia; Humans; Melatonin; Neuroprotective Agents; Nootropic

2010
Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review.
    International journal of geriatric psychiatry, 2010, Volume: 25, Issue:12

    Topics: Aged; Aged, 80 and over; Central Nervous System Depressants; Circadian Rhythm; Delirium; Dementia; F

2010
Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review.
    International journal of geriatric psychiatry, 2010, Volume: 25, Issue:12

    Topics: Aged; Aged, 80 and over; Central Nervous System Depressants; Circadian Rhythm; Delirium; Dementia; F

2010
Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review.
    International journal of geriatric psychiatry, 2010, Volume: 25, Issue:12

    Topics: Aged; Aged, 80 and over; Central Nervous System Depressants; Circadian Rhythm; Delirium; Dementia; F

2010
Effectiveness of melatonin treatment on circadian rhythm disturbances in dementia. Are there implications for delirium? A systematic review.
    International journal of geriatric psychiatry, 2010, Volume: 25, Issue:12

    Topics: Aged; Aged, 80 and over; Central Nervous System Depressants; Circadian Rhythm; Delirium; Dementia; F

2010
Fluctuations in cognition and alertness in Parkinson's disease and dementia.
    Neurology, 2004, Oct-26, Volume: 63, Issue:8 Suppl 3

    Topics: Awareness; Central Nervous System Stimulants; Cholinesterase Inhibitors; Cognition Disorders; Dement

2004
Melatonin relieves the neural oxidative burden that contributes to dementias.
    Annals of the New York Academy of Sciences, 2004, Volume: 1035

    Topics: Animals; Antioxidants; Apoptosis; Dementia; Free Radical Scavengers; Humans; Melatonin; Neurons; Oxi

2004
Melatonin for cognitive impairment.
    The Cochrane database of systematic reviews, 2006, Jan-25, Issue:1

    Topics: Antioxidants; Cognition Disorders; Dementia; Humans; Melatonin; Randomized Controlled Trials as Topi

2006
Sleep and aging: 2. Management of sleep disorders in older people.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2007, May-08, Volume: 176, Issue:10

    Topics: Adjuvants, Immunologic; Aged; Aging; Antidepressive Agents; Behavior Therapy; Benzodiazepines; Demen

2007
The treatment of sundowning. A selective review of pharmacological and nonpharmacological studies.
    Drugs & aging, 1997, Volume: 10, Issue:1

    Topics: Antipsychotic Agents; Chlormethiazole; Clozapine; Dementia; Humans; Melatonin; Phototherapy; Psychom

1997
Supplementary administration of artificial bright light and melatonin as potent treatment for disorganized circadian rest-activity and dysfunctional autonomic and neuroendocrine systems in institutionalized demented elderly persons.
    Chronobiology international, 2000, Volume: 17, Issue:3

    Topics: Aged; Circadian Rhythm; Dementia; Humans; Institutionalization; Melatonin; Neurosecretory Systems; P

2000
Apoptosis: biphasic dose responses.
    Critical reviews in toxicology, 2001, Volume: 31, Issue:4-5

    Topics: Animals; Antioxidants; Apoptosis; Cycloheximide; Dementia; Dimethylformamide; Dose-Response Relation

2001

Trials

6 trials available for melatonin and Amentia

ArticleYear
Progression of Dementia Assessed by Temporal Correlations of Physical Activity: Results From a 3.5-Year, Longitudinal Randomized Controlled Trial.
    Scientific reports, 2016, 06-13, Volume: 6

    Topics: Aged; Aged, 80 and over; Circadian Rhythm; Dementia; Disease Progression; Double-Blind Method; Exerc

2016
The preventative role of exogenous melatonin administration to patients with advanced cancer who are at risk of delirium: study protocol for a randomized controlled trial.
    Trials, 2016, 08-11, Volume: 17

    Topics: Central Nervous System Agents; Clinical Protocols; Dementia; Double-Blind Method; Feasibility Studie

2016
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
    JAMA, 2008, Jun-11, Volume: 299, Issue:22

    Topics: Activities of Daily Living; Affect; Aged, 80 and over; Circadian Rhythm; Cognition; Combined Modalit

2008
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
    JAMA, 2008, Jun-11, Volume: 299, Issue:22

    Topics: Activities of Daily Living; Affect; Aged, 80 and over; Circadian Rhythm; Cognition; Combined Modalit

2008
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
    JAMA, 2008, Jun-11, Volume: 299, Issue:22

    Topics: Activities of Daily Living; Affect; Aged, 80 and over; Circadian Rhythm; Cognition; Combined Modalit

2008
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
    JAMA, 2008, Jun-11, Volume: 299, Issue:22

    Topics: Activities of Daily Living; Affect; Aged, 80 and over; Circadian Rhythm; Cognition; Combined Modalit

2008
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
    JAMA, 2008, Jun-11, Volume: 299, Issue:22

    Topics: Activities of Daily Living; Affect; Aged, 80 and over; Circadian Rhythm; Cognition; Combined Modalit

2008
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
    JAMA, 2008, Jun-11, Volume: 299, Issue:22

    Topics: Activities of Daily Living; Affect; Aged, 80 and over; Circadian Rhythm; Cognition; Combined Modalit

2008
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
    JAMA, 2008, Jun-11, Volume: 299, Issue:22

    Topics: Activities of Daily Living; Affect; Aged, 80 and over; Circadian Rhythm; Cognition; Combined Modalit

2008
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
    JAMA, 2008, Jun-11, Volume: 299, Issue:22

    Topics: Activities of Daily Living; Affect; Aged, 80 and over; Circadian Rhythm; Cognition; Combined Modalit

2008
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
    JAMA, 2008, Jun-11, Volume: 299, Issue:22

    Topics: Activities of Daily Living; Affect; Aged, 80 and over; Circadian Rhythm; Cognition; Combined Modalit

2008
Double blind randomised placebo controlled trial of low dose melatonin for sleep disorders in dementia.
    International journal of geriatric psychiatry, 2002, Volume: 17, Issue:12

    Topics: Aged; Aged, 80 and over; Cross-Over Studies; Delayed-Action Preparations; Dementia; Double-Blind Met

2002
Actigraphy in agitated patients with dementia. Monitoring treatment outcomes.
    Zeitschrift fur Gerontologie und Geriatrie, 2007, Volume: 40, Issue:3

    Topics: Aged; Aged, 80 and over; Dementia; Dronabinol; Female; Humans; Male; Melatonin; Middle Aged; Monitor

2007
Bright light therapy and melatonin in motor restless behaviour in dementia: a placebo-controlled study.
    International journal of geriatric psychiatry, 2001, Volume: 16, Issue:1

    Topics: Aged; Aggression; Anticonvulsants; Combined Modality Therapy; Cross-Over Studies; Dementia; Double-B

2001

Other Studies

22 other studies available for melatonin and Amentia

ArticleYear
Chronic Light-Distorted Glutamate-Cortisol Signaling, Behavioral and Histological Markers, and Induced Oxidative Stress and Dementia: An Amelioration by Melatonin.
    ACS chemical neuroscience, 2022, 06-01, Volume: 13, Issue:11

    Topics: Animals; Biomarkers; Circadian Rhythm; Dementia; Dextromethorphan; Glutamic Acid; Hydrocortisone; Li

2022
Actigraphic and melatonin alignment in older adults with varying dementia risk.
    Chronobiology international, 2023, Volume: 40, Issue:2

    Topics: Actigraphy; Aged; Circadian Rhythm; Dementia; Humans; Light; Male; Melatonin; Sleep

2023
Actigraphic and melatonin alignment in older adults with varying dementia risk.
    Chronobiology international, 2023, Volume: 40, Issue:2

    Topics: Actigraphy; Aged; Circadian Rhythm; Dementia; Humans; Light; Male; Melatonin; Sleep

2023
Actigraphic and melatonin alignment in older adults with varying dementia risk.
    Chronobiology international, 2023, Volume: 40, Issue:2

    Topics: Actigraphy; Aged; Circadian Rhythm; Dementia; Humans; Light; Male; Melatonin; Sleep

2023
Actigraphic and melatonin alignment in older adults with varying dementia risk.
    Chronobiology international, 2023, Volume: 40, Issue:2

    Topics: Actigraphy; Aged; Circadian Rhythm; Dementia; Humans; Light; Male; Melatonin; Sleep

2023
Actigraphic and melatonin alignment in older adults with varying dementia risk.
    Chronobiology international, 2023, Volume: 40, Issue:2

    Topics: Actigraphy; Aged; Circadian Rhythm; Dementia; Humans; Light; Male; Melatonin; Sleep

2023
Actigraphic and melatonin alignment in older adults with varying dementia risk.
    Chronobiology international, 2023, Volume: 40, Issue:2

    Topics: Actigraphy; Aged; Circadian Rhythm; Dementia; Humans; Light; Male; Melatonin; Sleep

2023
Actigraphic and melatonin alignment in older adults with varying dementia risk.
    Chronobiology international, 2023, Volume: 40, Issue:2

    Topics: Actigraphy; Aged; Circadian Rhythm; Dementia; Humans; Light; Male; Melatonin; Sleep

2023
Actigraphic and melatonin alignment in older adults with varying dementia risk.
    Chronobiology international, 2023, Volume: 40, Issue:2

    Topics: Actigraphy; Aged; Circadian Rhythm; Dementia; Humans; Light; Male; Melatonin; Sleep

2023
Actigraphic and melatonin alignment in older adults with varying dementia risk.
    Chronobiology international, 2023, Volume: 40, Issue:2

    Topics: Actigraphy; Aged; Circadian Rhythm; Dementia; Humans; Light; Male; Melatonin; Sleep

2023
Effects of endogenous and exogenous N-acetyl-5-methoxy kynuramine on object recognition memory in male C3H mice.
    Hormones and behavior, 2023, Volume: 150

    Topics: Animals; Antioxidants; Dementia; Kynuramine; Male; Melatonin; Mice; Mice, Inbred C3H; Mice, Inbred I

2023
Bright Light Delights: Effects of Daily Light Exposure on Emotions, Restactivity Cycles, Sleep and Melatonin Secretion in Severely Demented Patients.
    Current Alzheimer research, 2017, Volume: 14, Issue:10

    Topics: Aged; Aged, 80 and over; Circadian Rhythm; Cohort Studies; Dementia; Emotions; Female; Humans; Light

2017
    Annals of clinical and laboratory science, 2018, Volume: 48, Issue:1

    Topics: Atherosclerosis; Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Melatonin; Mitochondria; Oxid

2018
Melatonin induces mechanisms of brain resilience against neurodegeneration.
    Journal of pineal research, 2018, Volume: 65, Issue:4

    Topics: Animals; Blotting, Western; Brain; Cognition; Dementia; Intercellular Signaling Peptides and Protein

2018
Lifetime coffee consumption, pineal gland volume, and sleep quality in late life.
    Sleep, 2018, 10-01, Volume: 41, Issue:10

    Topics: Aged; Aged, 80 and over; Caffeine; Coffee; Cognition; Dementia; Female; Humans; Imaging, Three-Dimen

2018
Creating the right light for older people.
    Health estate, 2014, Volume: 68, Issue:8

    Topics: Aged; Circadian Rhythm; Dementia; Equipment Design; Humans; Lighting; Melatonin; Phototherapy; Seaso

2014
[Symptomatic treatment in patients with dementia: light, but not melatonin, is probably worthwhile].
    Nederlands tijdschrift voor geneeskunde, 2008, Oct-25, Volume: 152, Issue:43

    Topics: Affect; Aged; Aged, 80 and over; Cognition; Dementia; Depression; Female; Humans; Male; Melatonin; P

2008
Brighter daytime lighting may improve dementia.
    Mayo Clinic health letter (English ed.), 2008, Volume: 26, Issue:11

    Topics: Antioxidants; Dementia; Female; Homes for the Aged; Humans; Lighting; Male; Melatonin; Nursing Homes

2008
[Symptomatic treatment of patients with dementia: light, but not melatonin, is probably worthwhile].
    Nederlands tijdschrift voor geneeskunde, 2008, Nov-01, Volume: 152, Issue:44

    Topics: Dementia; Evidence-Based Medicine; Humans; Melatonin; Phototherapy

2008
Altered temporal patterns of anxiety in aged and amyloid precursor protein (APP) transgenic mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jul-12, Volume: 108, Issue:28

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anxiety; Basal Nucleus of Meynert

2011
Clinical perspectives for the use of melatonin as a chronobiotic and cytoprotective agent.
    Annals of the New York Academy of Sciences, 2005, Volume: 1057

    Topics: Aging; Animals; Biological Clocks; Chronobiology Disorders; Circadian Rhythm; Dementia; Humans; Mela

2005
Patterns of plasma melatonin with ageing and mental condition: stability of nyctohemeral rhythms and differences in seasonal variations.
    Acta endocrinologica, 1984, Volume: 106, Issue:2

    Topics: Adult; Age Factors; Aged; Aging; Circadian Rhythm; Dementia; Female; Humans; Male; Melatonin; Middle

1984
Age- and mental health-related circadian rhythms of plasma levels of melatonin, prolactin, luteinizing hormone and follicle-stimulating hormone in man.
    The Journal of endocrinology, 1981, Volume: 91, Issue:3

    Topics: Adult; Age Factors; Aged; Circadian Rhythm; Dementia; Female; Follicle Stimulating Hormone; Humans;

1981
Rapid improvement of visuoperceptive functions by picoTesla range magnetic fields in patients with Parkinson's disease.
    The International journal of neuroscience, 1993, Volume: 70, Issue:3-4

    Topics: Dementia; Dopamine; Electromagnetic Fields; Humans; Male; Melatonin; Middle Aged; Parkinson Disease;

1993
Daily rhythm of serum melatonin in patients with dementia of the degenerate type.
    Brain research, 1996, Apr-22, Volume: 717, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Circadian Rhythm; Dementia; Female; Humans; Male; Melato

1996
Changes in endocrine circadian rhythms as markers of physiological and pathological brain aging.
    Chronobiology international, 1997, Volume: 14, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Aging; Brain; Circadian Rhythm; Dementi

1997
Possible antioxidant mechanism in melatonin reversal of aging and chronic ethanol-induced amnesia in plus-maze and passive avoidance memory tasks.
    Free radical biology & medicine, 2001, Mar-15, Volume: 30, Issue:6

    Topics: Aging; Alzheimer Disease; Amnesia; Animals; Antioxidants; Avoidance Learning; Data Interpretation, S

2001
Actigraphic sleep-wake patterns and urinary 6-sulfatoxymelatonin excretion in patients with Alzheimer's disease.
    Chronobiology international, 2001, Volume: 18, Issue:3

    Topics: Adult; Aged; Aging; Alzheimer Disease; Circadian Rhythm; Dementia; Female; Humans; Light; Male; Mela

2001
The therapeutic potential for tryptophan and melatonin: possible roles in depression, sleep, Alzheimer's disease and abnormal aging.
    Medical hypotheses, 1990, Volume: 31, Issue:3

    Topics: Aging; Animals; Bipolar Disorder; Dementia; Depressive Disorder; Humans; Melatonin; Mental Disorders

1990
Abnormal melatonin response to 5-methoxypsoralen in dementia.
    The American journal of psychiatry, 1989, Volume: 146, Issue:8

    Topics: Adult; Aged; Aging; Dementia; Depressive Disorder; Female; Furocoumarins; Humans; Male; Melatonin; M

1989