lysine and Obesity
lysine has been researched along with Obesity in 80 studies
Research
Studies (80)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (15.00) | 18.7374 |
| 1990's | 3 (3.75) | 18.2507 |
| 2000's | 11 (13.75) | 29.6817 |
| 2010's | 35 (43.75) | 24.3611 |
| 2020's | 19 (23.75) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Akhtar, A; Chatterjee, A; Pessoa Rodrigues, C; Shvedunova, M; Stehle, T; Szymanski, W; Wiese, M | 1 |
| Li, R; Qiao, J; Wang, S; Ye, Z; Zhang, C; Zhang, Y; Zhao, Y | 1 |
| Berendschot, TT; de Goei, EE; Eussen, SJ; Hanssen, H; Houben, AJ; Linkens, AM; Mari, A; Niessen, PM; Schalkwijk, CG; Scheijen, JL; Stehouwer, CD; Streese, L; Van den Eynde, MD; van den Waarenburg, MP; van Dongen, MC; van Gool, CC; Wijckmans, NE | 1 |
| Dumeaux, V; Kimmins, S; Lafleur, C; Lambrot, R; Pepin, AS | 1 |
| Kuang, Y; Liu, Y; Wang, D; Xiao, K; Zhang, G | 1 |
| Al Heialy, S; Al-Hroub, H; Elmoselhi, A; Hachim, M; Halwani, R; Jalaleddine, N; Kandasamy, RK; Mahboub, B; Saheb Sharif-Askari, N; Samuel Kurien, NM; Semreen, MH; Senok, A; Soares, NC | 1 |
| Bai, BL; Li, YQ; Lin, Y; Ma, LJ; Shi, L; Wang, H; Wu, HJ; Zhang, Q; Zou, JZ | 1 |
| Gordts, PLSM; Harrington, AR; Nora, C; Omar, I; Pollow, DP; Ramms, B; Sander, M; Wortham, M; Zhu, H | 1 |
| Li, Y; Liang, J; Liu, Y; Sun, C; Sun, Z | 1 |
| Diao, J; Han, S; Huang, S; Jia, M; Meng, Z; Pan, C; Sun, W; Sun, X; Tian, S; Wang, Q; Wang, Y; Yan, S; Zhu, W | 1 |
| Asghari, G; Azizi, F; Bordbar, M; Hoseinpour, S; Mirmiran, P; Roosta, S; Sarbazi, N; Teymoori, F | 1 |
| Crowe, DL; Kramer, K; Wu, J | 1 |
| Guo, Z; Li, Y; Liang, Y; Liu, Y; Qu, L; Sun, G; Wang, H; Wang, Y; Zhang, C | 1 |
| Cañellas, N; Correig, X; Escobar-Morreale, HF; Insenser, M; Luque-Ramírez, M; Martínez-García, MÁ | 1 |
| Caldez, MJ; Choi, H; Coppola, V; Eisenhaber, F; Goh, CMF; Gopinathan, L; Jones, OS; Kaldis, P; Kanagasundaram, Y; Kien, YL; Kurochkin, IV; Low, KN; Maurer-Stroh, S; Niska-Blakie, J; Ong, CB; Pfeiffenberger, E; Tessarollo, L | 1 |
| Hu, L; Ma, Q; Meng, Q; Shan, A; Shao, C; Sun, Y; Zhou, X; Zhu, J | 1 |
| Ren, J; Yang, M; Zhang, Y | 1 |
| Baskal, S; Besler, C; Büttner, P; Lurz, P; Thiele, H; Tsikas, D; Werner, S | 1 |
| Chen, L; Cui, C; Guo, X; He, Q; Hou, X; Hu, H; Li, D; Li, X; Liang, K; Song, J; Wang, C; Wang, X; Yan, F; Zang, N | 1 |
| Chen, C; Kim, YH; Li, H; Loo, D; Mosa, RM; Webster, JA; Yang, Z | 1 |
| Guimarães, DA; Manning, JR; O'Doherty, RM; Scott, I; Shiva, S; Stoner, MW; Thapa, D; Zhang, M | 1 |
| Dembinska-Kiec, A; Fedak, D; Gawlik, K; Goralska, J; Malczewska-Malec, M; Masania, J; Pawlica-Gosiewska, D; Rabbani, N; Razny, U; Solnica, B; Thornalley, P; Zdzienicka, A | 1 |
| Falgayrac, G; Kerckhofs, G; Luyten, F; Marin, C; Papantonakis, G; Penel, G; Sels, K; Van der Schueren, B; van Lenthe, GH; Vandamme, K; Vangoitsenhoven, R | 1 |
| Feng, Y; Ferguson, BS; Hostler, A; Payne, J; Quilici, D; Romanick, SS; Schlauch, K; Ulrich, C; Woolsey, R | 1 |
| Böhm, M; Ewen, S; Hohl, M; Kazakov, A; Kindermann, I; Laufs, U; Linz, D; Mahfoud, F; Selejan, SR; Speer, T; Tatu, AM; Zamyatkin, O | 1 |
| Archer, M; Eyre, DR; Hudson, DM; King, KB | 1 |
| Holland, WL; Katafuchi, T; Kittler, R; Kliewer, SA; Kollipara, RK; Mangelsdorf, DJ | 1 |
| Glendining, KA; Jasoni, CL | 1 |
| Chen, G; Feng, Z; Lu, J; Zheng, L; Zou, D | 1 |
| Badger, TM; Blackburn, ML; Borengasser, SJ; Faske, J; Gomez-Acevedo, H; Kang, P; Shankar, K | 1 |
| Antonini, SR; Barbieri, MA; Bettiol, H; Bueno, AC; de Castro, M; Elias Junior, J; Foss-Freitas, MC; Martins, CS; Miranda, W; Scherer, PE; Sun, K; Tao, C | 1 |
| Bierhaus, A; Blaak, EE; Buurman, WA; Gaens, KH; Goossens, GH; Greve, JW; Niessen, HW; Niessen, PM; Rensen, SS; Schalkwijk, CG; Stehouwer, CD; van der Kallen, CJ; van Greevenbroek, MM; van Zandvoort, MA | 1 |
| Bordner, AJ; Cordova, JM; Langlais, PR; Lefort, N; Mandarino, LJ; McLean, CG; Mielke, C; Ozkan, SB; Te, JA; Willis, WT | 1 |
| Alrob, OA; Fillmore, N; Gupta, MP; Jaswal, JS; Johnstone, DE; Lehner, R; Lopaschuk, GD; Ma, C; Michelakis, ED; Padwal, RS; Sack, MN; Sankaralingam, S; Sharma, AM; Wagg, CS | 1 |
| Dzwonek, A; Ledwon, JK; Majewska, A; Mikula, M; Ostrowski, J | 1 |
| Brindle, PK; Kasper, L; Matsumura, S; Montminy, M; Park, S; Paz, JC; Phillips, N; Tsai, WW; Wright, PE; Zhang, G; Zhou, MM | 1 |
| Cai, T; Du, Y; He, X; Li, T; Liu, P; Wei, P; Wei, T; Xue, P; Yang, F; Zhou, B | 1 |
| Cai, W; Díaz-Cisneros, FJ; Garay-Sevilla, ME; Macías-Cervantes, MH; Rodríguez-Soto, JM; Uribarri, J | 1 |
| Kayan-Tapan, T; Koçak, H; Öner-İyidoğan, Y; Seyithanoğlu, M; Tanrikulu-Küçük, S; Topparmak, E | 1 |
| Daniel, H; Ecker, J; Giesbertz, P; Höfle, AS; Padberg, I; Rein, D; Spanier, B | 1 |
| Lopes, PA; Madeira, MS; Martins, AP; Martins, SV; Moura, TF; Prates, JA; Santos, NC; Soveral, G | 1 |
| Floyd, ZE; Lama, R; Li, JJ; Liao, FF; Park, EA; Wang, R; Wang, X | 1 |
| Ahmad, MS; Ahmad, S; Alsaleh, M; Damanhouri, ZA; Holmes, E; Jamal, W; Kimhofer, T; Nicholson, JK; Wali, SO | 1 |
| Aller, R; Conde, R; de Luis, DA; Izaola, O; Sagrado, MG | 1 |
| Aller, R; Conde, R; de Luis, DA; Gonzalez Sagrado, M; Izaola, O | 1 |
| Brummer, RJ; Heitmann, BL; Nieuwenhuizen, AG; van Vught, AJ; Veldhorst, MA; Westerterp-Plantenga, MS | 1 |
| Fan, W; Li, P; Lu, M; Olefsky, JM; Pferdekamper, J; Saberi, M; Schenk, S | 1 |
| Chen, Z; Feng, G; He, L; Liu, Y; Liu, Z; Xu, H; Yang, Y; Yu, L; Zhang, D; Zhang, Z; Zhao, T; Zhou, D | 1 |
| Alt, FW; Bronson, RT; Chai, H; Deng, CX; Gao, J; Kurtev, MV; Lombard, DB; Schneider, JI; Schumacher, B; Schwer, B; Tsai, LH; Xiao, C | 1 |
| Crane, TE; Kroggel, MA; Kubota, C; Thomson, CA; Wertheim, BC; West, JL | 1 |
| Bloemen, JG; Buurman, WA; Dejong, CH; Driessen, A; Gaens, KH; Greve, JW; Hofker, MH; Niessen, PM; Rensen, SS; Schalkwijk, CG; Stehouwer, CD; Wolfs, MG | 1 |
| Brown, L; Fairlie, DP; Iyer, A | 1 |
| Botolin, S; Bucknell, A; King, KB; Oren, TW; Williams, A | 1 |
| Bruce, JE; Glaser, S; Hartil, K; Kurland, IJ; Vaitheesvaran, B; Yang, L; Yazulla, S | 1 |
| Accili, D; Farmer, SR; Gu, W; Kon, N; Lee, S; Qiang, L; Rosenbaum, M; Wang, L; Zhang, Y; Zhao, W; Zhao, Y | 1 |
| Li, Y; Niu, Y; Sun, C; Wang, C; Wang, F; Wang, M; Zhao, Y | 1 |
| Braud, S; Ciufolini, MA; Harosh, I | 1 |
| Barbeau, P; Harshfield, G; Kang, HS; Pollock, DM; Pollock, JS; Snieder, H; Treiber, FA | 1 |
| MOSES, A | 1 |
| Agretti, P; Ceccarini, G; Chiellini, C; Chiovato, L; Lisi, S; Maffei, M; Mammoli, C; Marsili, A; Pelosini, C; Pinchera, A; Rosellini, V; Santini, F; Scartabelli, G; Tonacchera, M; Vitti, P | 1 |
| Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Nangaku, M; Shibata, T; Sugiyama, S; Usuda, N; van Ypersele de Strihou, C | 1 |
| Albrechtsen, A; Borch-Johnsen, K; Ek, J; Glümer, C; Grarup, N; Hansen, T; Jørgensen, T; Pedersen, O; Urhammer, SA | 1 |
| de la Fuente, RA; de Luis Roman, D; Izaola, O; Sagrado, MG; Vicente, RC | 1 |
| Baatz, JE; Baynes, JW; Bethard, J; Blatnik, M; Brock, JW; Frizzell, N; Nagai, R; Thorpe, SR; Walla, MD | 1 |
| Izuhara, Y; Miyata, T; Nangaku, M; Ohtomo, S; Strihou, Cv; Takizawa, S | 1 |
| Carvalheira, JB; Carvalho-Filho, MA; Cintra, DE; De Souza, CT; Moraes, JC; Pauli, JR; Ropelle, ER; Saad, MJ; Velloso, LA | 1 |
| Heber, D; Henson, LC | 1 |
| Chagneau, AM; Cochard, T; Khoury, J; Leclercq, B | 1 |
| Chagneau, AM; Cochard, T; Leclercq, B; Pesti, GM | 1 |
| Andersen, R; Cheskin, LJ; Chung, WK; Elahi, D; Leibel, RL; Muller, D; Parikh, VV; Shuldiner, AR; Silver, K; Walston, J; Yao, F | 1 |
| Radcliffe, JD | 1 |
| Chu, SH; Hegsted, DM; Samonds, KW; Seronde, J | 1 |
| Hortling, H; Puupponen, E; Sundholm, I | 1 |
| Gylfe, E | 1 |
| Bergen, WG | 1 |
| Laurent de Angulo, MS; van Gelderen, HH | 1 |
| Lockwood, DH; Moxley, RT; Pozefsky, T; White, JJ | 1 |
| Dominguez, JM; Gallina, DL | 1 |
| Galli, V; Massolo, F | 1 |
Reviews
5 review(s) available for lysine and Obesity
| Article | Year |
|---|---|
Lysine-Specific Demethylase 1 in Energy Metabolism: A Novel Target for Obesity.
Topics: Diabetes Mellitus, Type 2; Energy Metabolism; Glucose; Histone Demethylases; Humans; Lysine; Obesity | 2022 |
Acetylation in cardiovascular diseases: Molecular mechanisms and clinical implications.
Topics: Acetylation; Animals; Cardiovascular Diseases; Cell Differentiation; Diabetes Mellitus; Energy Metabolism; Histone Acetyltransferases; Histone Deacetylases; Histones; Humans; Lysine; Obesity; Protein Processing, Post-Translational; Reperfusion Injury | 2020 |
Lysine acetylation in obesity, diabetes and metabolic disease.
Topics: Acetylation; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Energy Metabolism; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lysine; Obesity | 2012 |
Protein synthesis in animal models.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Composition; Dietary Fats; DNA; Fatty Acids, Nonesterified; Female; Growth Hormone; Liver; Lysine; Male; Models, Biological; Muscle Development; Muscle Proteins; Obesity; Peptide Elongation Factors; Protein Biosynthesis; Rats; Ribosomes; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; Swine; Transcription, Genetic | 1974 |
Rapid growth in chicks and infants.
Topics: Agriculture; Animal Nutritional Physiological Phenomena; Animals; Breast Feeding; Chickens; Deficiency Diseases; Diet, Reducing; Feeding Behavior; Female; Growth; Humans; Infant; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Lysine; Male; Milk; Obesity; Poultry; Pregnancy; Rats; Species Specificity | 1971 |
Trials
4 trial(s) available for lysine and Obesity
| Article | Year |
|---|---|
A 4-week high-AGE diet does not impair glucose metabolism and vascular function in obese individuals.
Topics: Diabetes Mellitus, Type 2; Diet; Glucose; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lipids; Lysine; Male; Obesity | 2022 |
Effect of an advanced glycation end product-restricted diet and exercise on metabolic parameters in adult overweight men.
Topics: Adipose Tissue; Adult; Blood Glucose; Body Mass Index; Diet; Diet, Reducing; Energy Intake; Exercise; Feeding Behavior; Glycation End Products, Advanced; Humans; Lipids; Lipoproteins, HDL; Lysine; Male; Middle Aged; Obesity; Overweight; Oxygen Consumption; Pyruvaldehyde; Triglycerides; Waist Circumference; Weight Loss | 2015 |
Influence of Lys656Asn polymorphism of leptin receptor gene on leptin response secondary to two hypocaloric diets: a randomized clinical trial.
Topics: Asparagine; Body Mass Index; Diet, Carbohydrate-Restricted; Diet, Fat-Restricted; Diet, Reducing; Dietary Carbohydrates; Dietary Fats; Female; Genotype; Humans; Leptin; Lysine; Male; Middle Aged; Obesity; Polymorphism, Genetic; Prospective Studies; Receptors, Leptin; Weight Loss | 2008 |
Increasing the vegetable intake dose is associated with a rise in plasma carotenoids without modifying oxidative stress or inflammation in overweight or obese postmenopausal women.
Topics: Aged; Arizona; Biomarkers; Body Mass Index; C-Reactive Protein; Carotenoids; Chronic Disease; Cross-Over Studies; Dinoprost; Female; Humans; Lysine; Middle Aged; Obesity; Overweight; Oxidative Stress; Postmenopause; Risk Factors; Vegetables | 2011 |
Other Studies
71 other study(ies) available for lysine and Obesity
| Article | Year |
|---|---|
Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice.
Topics: Acetylation; Adipocytes; Adipose Tissue; Amino Acids; Animals; Carbon; Diabetes Mellitus, Type 2; Diet, High-Fat; Gene Expression Regulation; Genetic Predisposition to Disease; Glucose; Glucose Transporter Type 4; Haploinsufficiency; Histone Acetyltransferases; Histones; Lipid Metabolism; Lysine; Mice; Obesity; PPAR gamma | 2021 |
Amino acid signatures in relation to polycystic ovary syndrome and increased risk of different metabolic disturbances.
Topics: Alanine; Amino Acids; Body Mass Index; Female; Glycine; Humans; Insulin Resistance; Lysine; Metabolic Syndrome; Obesity; Polycystic Ovary Syndrome; Tyrosine | 2022 |
Sperm histone H3 lysine 4 tri-methylation serves as a metabolic sensor of paternal obesity and is associated with the inheritance of metabolic dysfunction.
Topics: Animals; Chromatin; DNA Methylation; Female; Histones; Lysine; Male; Mice; Mice, Inbred C57BL; Obesity; Placenta; Pregnancy; Spermatozoa | 2022 |
N6-Acetyl-L-Lysine and p-Cresol as Key Metabolites in the Pathogenesis of COVID-19 in Obese Patients.
Topics: COVID-19; Cresols; Humans; Lysine; Metabolomics; Obesity; SARS-CoV-2 | 2022 |
Increasing angiotensin-converting enzyme 1 regulated by histone 3 lysine 27 hyperacetylation in high-fat diet-induced hypertensive rat kidney.
Topics: Angiotensins; Animals; Blood Pressure; Diet, High-Fat; Histones; Hypertension; Kidney; Lysine; Male; Obesity; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System | 2022 |
Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity.
Topics: Animals; Diabetes Mellitus, Type 2; Histone Demethylases; Inflammation; Insulin; Insulin Resistance; Lipid Metabolism; Lipids; Liver; Lysine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity | 2022 |
Non-Histone Lysine Crotonylation Is Involved in the Regulation of White Fat Browning.
Topics: Adipose Tissue, White; Animals; Chromatography, Liquid; Lysine; Mice; Obesity; Protein Processing, Post-Translational; Tandem Mass Spectrometry | 2022 |
A new strategy to alleviate the obesity induced by endocrine disruptors-A unique lysine metabolic pathway of nanoselenium Siraitia grosvenorii to repair gut microbiota and resist obesity.
Topics: Acetyl Coenzyme A; Diet, High-Fat; Endocrine Disruptors; Gastrointestinal Microbiome; Humans; Lysine; Metabolic Networks and Pathways; Obesity; RNA, Ribosomal, 16S | 2023 |
Dietary amino acids and anthropometric indices: Tehran Lipid and Glucose Study.
Topics: Adult; Amino Acids; Aspartic Acid; Body Mass Index; Cysteine; Glutamates; Humans; Iran; Lipids; Lysine; Obesity; Overweight; Risk Factors; Tryptophan; Waist Circumference | 2023 |
Lysine metabolism is a novel metabolic tumor suppressor pathway in breast cancer.
Topics: Acetoacetates; Animals; Breast Neoplasms; Female; Humans; Lysine; Mice; Obesity; PPAR gamma; Tumor Microenvironment | 2023 |
Dietary intakes of methionine, threonine, lysine, arginine and histidine increased risk of type 2 diabetes in Chinese population: does the mediation effect of obesity exist?
Topics: Amino Acids; Arginine; Diabetes Mellitus, Type 2; Diet; East Asian People; Histidine; Humans; Lysine; Male; Methionine; Obesity; Racemethionine; Risk Factors; Threonine | 2023 |
Serum metabolomics profiling by proton nuclear magnetic resonance spectrometry of the response to single oral macronutrient challenges in women with polycystic ovary syndrome (PCOS) compared with male and female controls.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Female; Glucose; Humans; Insulin Resistance; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Nutrients; Obesity; Polycystic Ovary Syndrome; Protons; Young Adult | 2023 |
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
Topics: Aging; Animals; Anti-Bacterial Agents; Bacteria; Carnitine; Coenzyme A-Transferases; Dietary Supplements; Feces; Gastrointestinal Microbiome; Humans; Kidney; Lipid Metabolism; Liver; Lysine; Metabolic Syndrome; Metabolome; Mice; Mice, Knockout; Obesity; Tryptophan | 2020 |
Threonine, but Not Lysine and Methionine, Reduces Fat Accumulation by Regulating Lipid Metabolism in Obese Mice.
Topics: Adipose Tissue, Brown; Animals; Anti-Obesity Agents; Diet, High-Fat; Humans; Insulin Resistance; Lipid Metabolism; Lipogenesis; Lysine; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Threonine; Uncoupling Protein 1 | 2020 |
Profile of urinary amino acids and their post-translational modifications (PTM) including advanced glycation end-products (AGEs) of lysine, arginine and cysteine in lean and obese ZSF1 rats.
Topics: Animals; Arginine; Creatinine; Cysteine; Glucose; Glycation End Products, Advanced; Heart Failure; Lysine; Obesity; Protein Processing, Post-Translational; Rats; Stroke Volume | 2022 |
Mof acetyltransferase inhibition ameliorates glucose intolerance and islet dysfunction of type 2 diabetes via targeting pancreatic α-cells.
Topics: Acetylation; Animals; Apoptosis; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Gene Regulatory Networks; Glucagon-Secreting Cells; Glucose Intolerance; Histone Acetyltransferases; Histones; Lysine; Mice, Inbred C57BL; Obesity; Proprotein Convertase 1; Salicylates | 2021 |
Collagen beta (1-
Topics: Adipocytes; Adiponectin; Animals; Cell Line; Diet, High-Fat; Galactosyltransferases; HEK293 Cells; Humans; Lipid Metabolism; Lipids; Lysine; Male; Mice; Mice, Inbred C57BL; Molecular Weight; Obesity; Protein Processing, Post-Translational | 2017 |
Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetylation; Acetyltransferases; Acyl-CoA Dehydrogenase; Animals; Cell Line; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Fatty Acids; Gene Expression Regulation, Enzymologic; Lysine; Male; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondrial Proteins; Myocytes, Cardiac; Nerve Tissue Proteins; Obesity; Oxidation-Reduction; Protein Processing, Post-Translational; Pyruvate Dehydrogenase Complex; Rats; RNA Interference; Sirtuin 3; Sirtuins; Time Factors; Transfection | 2017 |
Relation of the protein glycation, oxidation and nitration to the osteocalcin level in obese subjects.
Topics: Adult; Aged; Antioxidants; Biomarkers; Case-Control Studies; Female; Glycation End Products, Advanced; Humans; Kynurenine; Lysine; Male; Middle Aged; Obesity; Osteocalcin; Oxidative Stress; Proteins | 2017 |
Unraveling the compromised biomechanical performance of type 2 diabetes- and Roux-en-Y gastric bypass bone by linking mechanical-structural and physico-chemical properties.
Topics: Animals; Arginine; Biomechanical Phenomena; Bone and Bones; Diabetes Mellitus, Type 2; Female; Fractures, Bone; Gastric Bypass; Glycation End Products, Advanced; Humans; Lysine; Male; Mice; Mice, Obese; Obesity; Skeleton; Tomography, X-Ray Computed; Weight Loss | 2018 |
Obesity-mediated regulation of cardiac protein acetylation: parallel analysis of total and acetylated proteins via TMT-tagged mass spectrometry.
Topics: Animals; Diet, High-Fat; Heart Ventricles; Lysine; Male; Mice, Inbred C57BL; Obesity; Protein Processing, Post-Translational; Proteins; Proteome; Tandem Mass Spectrometry; Ventricular Remodeling | 2018 |
Sympathoadrenergic suppression improves heart function by upregulating the ratio of sRAGE/RAGE in hypertension with metabolic syndrome.
Topics: ADAM10 Protein; Analysis of Variance; Animals; Denervation; Disease Models, Animal; Fibroblasts; HMGB1 Protein; Hypertension; Kidney; Leukocytes, Mononuclear; Ligands; Lysine; Male; Metabolic Syndrome; Myocardium; Obesity; Protein Isoforms; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Adrenergic, beta; Statistics, Nonparametric; Sympathetic Nervous System; Up-Regulation | 2018 |
Glycation of type I collagen selectively targets the same helical domain lysine sites as lysyl oxidase-mediated cross-linking.
Topics: Amino Acid Sequence; Amino Acids; Animals; Blood Glucose; Collagen Type I; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Disease Models, Animal; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Hydroxylation; Hydroxylysine; Lysine; Male; Mass Spectrometry; Mice; Obesity; Protein-Lysine 6-Oxidase; Tail; Tendons | 2018 |
PPARγ-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice.
Topics: Adipose Tissue; Adiposity; Amino Acid Motifs; Animals; Female; Humans; Insulin; Lysine; Male; Mice; Mutation, Missense; Obesity; PPAR gamma; SUMO-1 Protein; Sumoylation | 2018 |
Maternal High Fat Diet-Induced Obesity Modifies Histone Binding and Expression of
Topics: Animals; Diet, High-Fat; Female; Hippocampus; Histones; Lysine; Male; Mice, Inbred C57BL; Obesity; Promoter Regions, Genetic; Protein Binding; Receptors, Oxytocin; RNA, Messenger; Sex Characteristics | 2019 |
Synergistic effect of LEP and LEPR gene polymorphism on body mass index in a Chinese population.
Topics: Adult; Alleles; Arginine; Asian People; Asparagine; Body Mass Index; China; Female; Genetic Predisposition to Disease; Genotype; Humans; Leptin; Logistic Models; Lysine; Male; Obesity; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Polymorphism, Single-Stranded Conformational; Prevalence; Receptors, Leptin; Risk Factors; Waist-Hip Ratio | 2013 |
High fat diet and in utero exposure to maternal obesity disrupts circadian rhythm and leads to metabolic programming of liver in rat offspring.
Topics: Animals; Biological Clocks; Circadian Rhythm; Diet, High-Fat; Female; Gene Expression Regulation; Histones; Liver; Lysine; Models, Biological; Obesity; PPAR alpha; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sirtuin 1; Transcription Initiation Site | 2014 |
A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome.
Topics: Adiponectin; Adult; Age of Onset; Amino Acid Substitution; Cardiovascular Diseases; Case-Control Studies; Female; Humans; Lysine; Male; Metabolic Syndrome; Methionine; Middle Aged; Molecular Weight; Mutation, Missense; Obesity; Protein Multimerization; Young Adult | 2014 |
Nε-(carboxymethyl)lysine-receptor for advanced glycation end product axis is a key modulator of obesity-induced dysregulation of adipokine expression and insulin resistance.
Topics: Adipokines; Adipose Tissue; Adult; Animals; Cells, Cultured; Female; Humans; Insulin Resistance; Lipid Metabolism; Lysine; Male; Mice; Mice, Inbred C57BL; Middle Aged; Obesity; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2014 |
Adenine nucleotide translocase is acetylated in vivo in human muscle: Modeling predicts a decreased ADP affinity and altered control of oxidative phosphorylation.
Topics: Acetylation; Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adult; Binding Sites; Body Mass Index; Down-Regulation; Female; Humans; Insulin Resistance; Lysine; Male; Middle Aged; Mitochondria, Muscle; Molecular Docking Simulation; Molecular Dynamics Simulation; Motor Activity; Muscle Proteins; Muscle, Skeletal; Obesity; Oxidative Phosphorylation; Protein Processing, Post-Translational | 2014 |
Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.
Topics: Acetylation; Acyl-CoA Dehydrogenase, Long-Chain; Animals; Fatty Acids; Heart; Insulin; Lysine; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Obesity; Oxidation-Reduction; Signal Transduction; Sirtuin 3 | 2014 |
Obesity increases histone H3 lysine 9 and 18 acetylation at Tnfa and Ccl2 genes in mouse liver.
Topics: Acetylation; Animals; Cell Line, Tumor; Chemokine CCL2; Chromatin Immunoprecipitation; Diet, High-Fat; DNA Polymerase II; Fatty Liver; Gene Expression; Histones; Lipopolysaccharides; Liver; Lysine; Male; Mice, Inbred C57BL; Mice, Obese; NF-kappa B; Obesity; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2014 |
Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation.
Topics: 3T3-L1 Cells; Acetylation; Adipocytes; Animals; Cells, Cultured; CREB-Binding Protein; Cyclic AMP Response Element-Binding Protein; Embryo, Mammalian; Fibroblasts; Gene Expression Profiling; HEK293 Cells; Humans; Immunoblotting; Lysine; Mice; Mice, Knockout; Mice, Obese; Mutation; Obesity; Oligonucleotide Array Sequence Analysis; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Signal Transduction; Sirtuin 1 | 2014 |
Lysine malonylation is elevated in type 2 diabetic mouse models and enriched in metabolic associated proteins.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Liver; Lysine; Mice, Inbred C57BL; Obesity; Protein Processing, Post-Translational; Proteins | 2015 |
Serum fetuin-A and arginase-1 in human obesity model: Is there any interaction between inflammatory status and arginine metabolism?
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Arginase; Arginine; Biomarkers; C-Reactive Protein; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leptin; Linear Models; Liver Function Tests; Lysine; Male; Middle Aged; Nitrates; Nitrites; Obesity | 2015 |
Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Fatty Acids; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Glyoxylates; Insulin Resistance; Leptin; Liver; Lysine; Male; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle, Skeletal; Obesity; Phosphotyrosine; Signal Transduction; Sorbitol | 2015 |
Higher membrane fluidity mediates the increased subcutaneous fatty acid content in pigs fed reduced protein diets.
Topics: Adipose Tissue; Animals; Body Composition; Breeding; Diet, Protein-Restricted; Dietary Proteins; Diphenylhexatriene; Fatty Acids; Lysine; Male; Membrane Fluidity; Obesity; Red Meat; Subcutaneous Fat; Swine | 2017 |
Ubiquitin Ligase NEDD4 Regulates PPARγ Stability and Adipocyte Differentiation in 3T3-L1 Cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Cell Differentiation; CHO Cells; Cricetinae; Cricetulus; Gene Knockdown Techniques; HEK293 Cells; Humans; Ligands; Lysine; Mice; Nedd4 Ubiquitin Protein Ligases; Obesity; PPAR gamma; Protein Binding; Protein Domains; Protein Stability; Proteolysis; Ubiquitination | 2016 |
Metabolic Phenotype of Obesity in a Saudi Population.
Topics: Adolescent; Adult; Amino Acids, Branched-Chain; Bile Acids and Salts; Blood Glucose; Cholesterol; Female; Humans; Liver; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylamines; Obesity; Saudi Arabia; Triglycerides | 2017 |
Influence of Lys656Asn polymorphism of leptin receptor gene on insulin resistance in patients with diabetes mellitus type 2.
Topics: Amino Acid Substitution; Asparagine; Body Mass Index; Cytokines; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Lysine; Obesity; Polymorphism, Genetic; Receptors, Leptin | 2008 |
Association between dietary protein and change in body composition among children (EYHS).
Topics: Adolescent; Aging; Algorithms; Arginine; Body Composition; Body Mass Index; Child; Dietary Proteins; Female; Health Surveys; Humans; Lysine; Male; Motor Activity; Obesity; Puberty; Sex Characteristics; Social Class | 2009 |
Inducible nitric oxide synthase deficiency in myeloid cells does not prevent diet-induced insulin resistance.
Topics: Animals; Blotting, Western; Bone Marrow Transplantation; Cells, Cultured; Dietary Fats; Enzyme Inhibitors; Immunohistochemistry; Insulin Resistance; Lysine; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; Nitric Oxide Synthase Type II; Obesity | 2010 |
The ENPP1 K121Q polymorphism is not associated with type 2 diabetes or obesity in the Chinese Han population.
Topics: Aged; Amino Acid Substitution; Asian People; Diabetes Mellitus, Type 2; Female; Genetics, Population; Genome-Wide Association Study; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Obesity; Phosphoric Diester Hydrolases; Polymorphism, Single Nucleotide; Pyrophosphatases | 2011 |
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.
Topics: Acetylation; Animals; Body Weight; Brain; Female; Growth; Histones; Lysine; Male; Mice; Mice, Knockout; Neurons; Obesity; Sirtuins | 2010 |
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis.
Topics: Aged; Biomarkers; Biopsy; Cytokines; Enzyme Inhibitors; Fatty Liver; Female; Gene Expression; Guanidines; Hep G2 Cells; Hepatocytes; Humans; In Vitro Techniques; Liver; Lysine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Pyridoxamine; Vitamin B Complex | 2012 |
Arthroplasty in veterans: analysis of cartilage, bone, serum, and synovial fluid reveals differences and similarities in osteoarthritis with and without comorbid diabetes.
Topics: Aged; Aged, 80 and over; Arginine; Arthroplasty, Replacement, Knee; Biomarkers; Cartilage; Case-Control Studies; Collagen; Colorado; Comorbidity; Cross-Linking Reagents; Cross-Sectional Studies; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Obesity; Osteoarthritis, Knee; Prospective Studies; Synovial Fluid; Veterans | 2011 |
Peripheral effects of FAAH deficiency on fuel and energy homeostasis: role of dysregulated lysine acetylation.
Topics: Acetyl Coenzyme A; Acetylation; Amidohydrolases; Animals; Energy Metabolism; Gene Expression Regulation, Enzymologic; Glucose; Homeostasis; Humans; Lipid Metabolism; Liver; Lysine; Mice; Mice, Knockout; Obesity | 2012 |
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ.
Topics: 3T3 Cells; Acetylation; Adipose Tissue, Brown; Adipose Tissue, White; Adult; Amino Acid Sequence; Animals; Cells, Cultured; Energy Metabolism; Female; Humans; Insulin Resistance; Ligands; Lysine; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Obesity; PPAR gamma; Resveratrol; Sequence Alignment; Sirtuin 1; Stilbenes; Thermogenesis; Thiazolidinediones | 2012 |
Activated glucose-6-phosphate dehydrogenase is associated with insulin resistance by upregulating pentose and pentosidine in diet-induced obesity of rats.
Topics: Animals; Arginine; Diet, High-Fat; Enzyme Activation; Glucosephosphate Dehydrogenase; Insulin Resistance; Lysine; Male; Obesity; Oxidative Stress; Pentoses; Rats; Rats, Wistar; Up-Regulation | 2012 |
Enteropeptidase: a gene associated with a starvation human phenotype and a novel target for obesity treatment.
Topics: Administration, Oral; Amino Acid Motifs; Animals; Arginine; Biological Availability; Body Weight; Dose-Response Relationship, Drug; Drug Design; Eating; Enteropeptidase; Feeding Behavior; Humans; Lysine; Mice; Microvilli; Models, Chemical; Models, Genetic; Obesity; Phenotype; Starvation; Triglycerides | 2012 |
Endothelin-1 gene Lys198Asn polymorphism and blood pressure reactivity.
Topics: Adolescent; Adult; Asparagine; Black People; Blood Pressure; Cold Temperature; Endothelin-1; Female; Forehead; Gene Frequency; Genotype; Hemodynamics; Heterozygote; Humans; Lysine; Male; Nitric Oxide; Obesity; Polymorphism, Genetic; Socioeconomic Factors; Stress, Physiological; Video Games; White People | 2003 |
DIABETES INSIPIDUS.
Topics: Arginine Vasopressin; Diabetes Insipidus; Diabetes Insipidus, Neurogenic; Humans; Hypertension; Lysine; Obesity; Vasopressins | 1964 |
Genetic screening for melanocortin-4 receptor mutations in a cohort of Italian obese patients: description and functional characterization of a novel mutation.
Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Animals; Child; Chlorocebus aethiops; Cohort Studies; COS Cells; Female; Genetic Testing; Glutamic Acid; Heterozygote; Humans; Italy; Lysine; Male; Middle Aged; Mutation; Mutation, Missense; Obesity; Pedigree; Phenylalanine; Receptor, Melanocortin, Type 4; Serine | 2004 |
In a type 2 diabetic nephropathy rat model, the improvement of obesity by a low calorie diet reduces oxidative/carbonyl stress and prevents diabetic nephropathy.
Topics: Animals; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diet, Fat-Restricted; Disease Models, Animal; Female; Follow-Up Studies; Glycation End Products, Advanced; Immunohistochemistry; Kidney; Lysine; Male; Microscopy, Electron; Obesity; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Wistar | 2005 |
Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.
Topics: Adult; Aged; Blood Glucose; Body Mass Index; Case-Control Studies; Cohort Studies; Denmark; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Glucose Tolerance Test; Glutamine; Humans; Insulin Resistance; Lysine; Male; Middle Aged; Obesity; Odds Ratio; Phosphoric Diester Hydrolases; Polymorphism, Genetic; Pyrophosphatases; Regression Analysis; White People | 2006 |
Leptin receptor Lys656Asn polymorphism is associated with decreased leptin response and weight loss secondary to a lifestyle modification in obese patients.
Topics: Adult; Asparagine; Body Mass Index; Exercise; Female; Humans; Leptin; Life Style; Lysine; Male; Middle Aged; Obesity; Polymorphism, Genetic; Receptors, Cell Surface; Receptors, Leptin; Weight Loss | 2006 |
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.
Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Biomarkers; Cell Differentiation; Citric Acid Cycle; Cysteine; Diabetes Complications; Diabetes Mellitus, Type 2; Fibroblasts; Fumarates; Humans; Insulin Resistance; Lysine; Mice; Mitochondria; Obesity; Protein Processing, Post-Translational; Risk Factors; Stress, Physiological; Succinic Acid; Sulfhydryl Compounds | 2007 |
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model.
Topics: Animals; Antimutagenic Agents; Arginine; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Blotting, Western; Chromatography, High Pressure Liquid; Cobalt; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Gene Expression; Glycation End Products, Advanced; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immediate-Early Proteins; Insulin-Like Growth Factor Binding Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; NADPH Oxidases; Obesity; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta | 2008 |
Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats.
Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinase Kinases; Animals; Diet; Disease Models, Animal; Enzyme Inhibitors; Insulin Receptor Substrate Proteins; Insulin Resistance; Lysine; Male; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Obesity; Physical Conditioning, Animal; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Insulin; S-Nitrosoglutathione; Signal Transduction | 2008 |
Whole body protein breakdown rates and hormonal adaptation in fasted obese subjects.
Topics: Adult; Amino Acids, Branched-Chain; Fasting; Glucagon; Hormones; Humans; Hydrocortisone; Insulin; Lysine; Nitrogen; Obesity; Proteins; Thyroid Hormones | 1983 |
Comparative responses of genetically lean and fat chickens to lysine, arginine and non-essential amino acid supply. I. Growth and body composition.
Topics: Amino Acids; Animals; Arginine; Body Composition; Chickens; Diet; Diet, Protein-Restricted; Dietary Proteins; Growth; Lysine; Male; Obesity; Thinness; Weight Gain | 1994 |
Comparative responses of genetically lean and fat chickens to lysine, arginine and non-essential amino acid supply. II. Plasma amino acid responses.
Topics: Amino Acids; Amino Acids, Essential; Animals; Arginine; Chickens; Diet; Diet, Protein-Restricted; Dietary Proteins; Lysine; Male; Obesity; Thinness | 1994 |
The Gln223Arg and Lys656Asn polymorphisms in the human leptin receptor do not associate with traits related to obesity.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Asparagine; Blood Glucose; Body Constitution; Body Mass Index; Carrier Proteins; Female; Glutamine; Heterozygote; Homozygote; Humans; Insulin; Lysine; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Cell Surface; Receptors, Leptin; Reference Values; Socioeconomic Factors | 1997 |
The effect of increasing the dietary lysine concentrat.ion on food intake and growth in the Zucker rat.
Topics: Animals; Diet; Energy Intake; Female; Food, Fortified; Glutens; Growth; Lysine; Obesity; Phenotype; Rats | 1977 |
Protein utilization and lysine metabolism in obese and non-obese growing rats.
Topics: Animals; Dietary Proteins; Energy Metabolism; Fatty Liver; Lysine; Male; Obesity; Protein Deficiency; Rats; Saccharopine Dehydrogenases; Species Specificity | 1978 |
The vasopressin test as an aid in the evaluation of hypothalamo-pituitary-adrenal function.
Topics: Adrenocorticotropic Hormone; Estrogens; Female; Glucocorticoids; Humans; Hypogonadism; Hypopituitarism; Hypothalamo-Hypophyseal System; Injections, Intramuscular; Injections, Intravenous; Lysine; Male; Menstruation Disturbances; Obesity; Pituitary Function Tests; Prednisolone; Turner Syndrome; Vasopressins | 1971 |
Changes of free amino acids in pancreatic beta-cells after starvation and substrate deprivation.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography, Thin Layer; Dansyl Compounds; Diabetes Mellitus; Fasting; Female; Freeze Drying; Glutamates; Glycine; Islets of Langerhans; Leucine; Lysine; Mice; Obesity; Ornithine; Phenylalanine; Proline; Taurine; Tritium; Valine | 1974 |
Comparative study of three tests for the assessment of hypothalamic-pituitary-adrenocortical function.
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Adolescent; Adrenal Glands; Adrenal Insufficiency; Blood Glucose; Child; Child, Preschool; Dwarfism; Evaluation Studies as Topic; Female; Humans; Hypoglycemia; Hypopituitarism; Hypothalamus; Insulin; Lysine; Male; Metyrapone; Obesity; Pituitary Gland; Pituitary-Adrenal Function Tests; Time Factors; Vasopressins | 1972 |
Transient kwaskiorkor: A cause of fatty liver following small bowel bypass.
Topics: Adult; Amino Acids; Body Weight; Dietary Carbohydrates; Dietary Proteins; Fatty Liver; Female; Glycine; Humans; Ileum; Intestinal Absorption; Intestine, Small; Kwashiorkor; Leucine; Lipid Metabolism; Liver; Lysine; Malabsorption Syndromes; Male; Obesity | 1974 |
Human utilization of urea nitrogen in low calorie diets.
Topics: Adult; Amino Acids; Animals; Basal Metabolism; Body Weight; Diet, Reducing; Dietary Carbohydrates; Female; Humans; Lysine; Methionine; Milk; Nitrogen; Nutritional Requirements; Obesity; Time Factors; Urea | 1971 |
[Evaluation of the function of the hypothalamus-hypophysis-adrenal gland system in obese children by means of the metopyrone and the lysine-8-vasopressin tests].
Topics: Adolescent; Adrenal Glands; Child; Child, Preschool; Fatty Acids, Nonesterified; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Lysine; Male; Metyrapone; Obesity; Pituitary Function Tests; Pituitary Gland; Vasopressins | 1969 |