Page last updated: 2024-10-30

losartan and Gout

losartan has been researched along with Gout in 17 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.

Research Excerpts

ExcerptRelevanceReference
"Although allopurinol has been available for approximately 50 years, hyperuricemia and its sequelae are not only prevalent, but the incidence and costs associated with this disorder continue to increase."8.82Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase. ( Bomalaski, JS; Clark, MA, 2004)
"To report a case of angioedema associated with losartan administration."7.70Losartan-induced angioedema. ( Rivera, JO, 1999)
"Losartan has been shown to increase urinary uric acid excretion and hence to lower serum uric acid levels."6.70Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia and gout. ( Brunner, HR; Burnier, M; Chiolero, A; Fallab-Stubi, CL; Gerster, JC; Maillard, M; Würzner, G, 2001)
"Although allopurinol has been available for approximately 50 years, hyperuricemia and its sequelae are not only prevalent, but the incidence and costs associated with this disorder continue to increase."4.82Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase. ( Bomalaski, JS; Clark, MA, 2004)
"To report a case of angioedema associated with losartan administration."3.70Losartan-induced angioedema. ( Rivera, JO, 1999)
"Losartan has been shown to increase urinary uric acid excretion and hence to lower serum uric acid levels."2.70Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia and gout. ( Brunner, HR; Burnier, M; Chiolero, A; Fallab-Stubi, CL; Gerster, JC; Maillard, M; Würzner, G, 2001)
"Gout is increasing worldwide."2.49Hypertension, its treatment, hyperuricaemia and gout. ( Gibson, TJ, 2013)
"Diagnosis of gout is established when typical monosodium urate crystals can be identified."2.44[Involvement of the foot in metabolic diseases]. ( Gerster, JC, 2007)
"Thus, the treatment of hypertension and hyperlipidemia associated with hyperuricemia is also important."2.44[Other antihyperuricemic agents]. ( Hisatome, I; Igawa, O; Ogino, K, 2008)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's7 (41.18)29.6817
2010's6 (35.29)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Saad, M1
Castilla-Ojo, N1
Turkson-Ocran, RA1
Conlin, PR1
Appel, LJ1
Miller, ER1
Juraschek, SP1
Ashcroft, JA1
Saar, J1
Kirch, W1
Vatseba, MO1
Bundrick, JB1
Litin, SC1
Perez-Ruiz, F2
Herrero-Beites, AM1
Carmona, L1
Gibson, TJ1
Bomalaski, JS1
Clark, MA1
Tatsuno, I1
Gerster, JC2
Ogino, K1
Igawa, O1
Hisatome, I1
Jones, RE1
Ball, EV1
Rivera, JO1
Würzner, G1
Chiolero, A1
Maillard, M1
Fallab-Stubi, CL1
Brunner, HR1
Burnier, M1
Liberopoulos, E1
Christides, D1
Elisaf, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Losartan and Uric Acid Metabolism in Children With Proteinuric Nephropathies: a Cross-over Randomized Clinical Trail[NCT05402397]Phase 440 participants (Anticipated)Interventional2022-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for losartan and Gout

ArticleYear
Hypertension, its treatment, hyperuricaemia and gout.
    Current opinion in rheumatology, 2013, Volume: 25, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Diuretics; Female; Gout; Humans; Hypertension; Hyperuricemi

2013
Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase.
    Current rheumatology reports, 2004, Volume: 6, Issue:3

    Topics: Allopurinol; Amlodipine; Clinical Trials as Topic; Enzyme Inhibitors; Febuxostat; Gout; Humans; Hype

2004
[Hyperuricemia in hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Calcium Channel Blockers; Diet, Sodium-Restricte

2004
[Involvement of the foot in metabolic diseases].
    Praxis, 2007, Aug-22, Volume: 96, Issue:34

    Topics: Achilles Tendon; Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Apatites; Chon

2007
[Other antihyperuricemic agents].
    Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:4

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Drug Therapy, Combination; Fenofibrate; Gout; Gout

2008

Trials

2 trials available for losartan and Gout

ArticleYear
Effects of the DASH diet and losartan on serum urate among adults with hypertension: Results of a randomized trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:10

    Topics: Adult; Dietary Approaches To Stop Hypertension; Female; Gout; Humans; Hypertension; Hyperuricemia; L

2023
Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia and gout.
    Journal of hypertension, 2001, Volume: 19, Issue:10

    Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Chronic Disease; Cross-Over Studies; Double-Blind

2001

Other Studies

10 other studies available for losartan and Gout

ArticleYear
Hyperuricemia and Gout: The Role of Losartan.
    The Senior care pharmacist, 2023, Sep-01, Volume: 38, Issue:9

    Topics: Antihypertensive Agents; Gout; Humans; Hyperuricemia; Losartan

2023
Alternatives to specific uric acid lowering treatment in gout in patients with cardiovascular disease.
    BMJ (Clinical research ed.), 2018, Sep-20, Volume: 362

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atorvastatin; Calcium Channel Blockers; Cardiov

2018
[A new application for well-known pharmaceutics--losartan and fenofibrate as potential remedies against gout?].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Fenofibrate; Gout; Gout Suppressants; Humans; Hypolipidemic

2014
[Endothelial dysfunction as a marker of vascular aging syndrome on the background of hypertension, coronary heart disease, gout and obesity].
    Likars'ka sprava, 2013, Issue:6

    Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Cardiovascular Agents; Carotid Arterie

2013
Clinical pearls in general internal medicine.
    Mayo Clinic proceedings, 2011, Volume: 86, Issue:1

    Topics: Abdominal Pain; Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Androgen Antagonists; Anti-Inf

2011
A two-stage approach to the treatment of hyperuricemia in gout: the "dirty dish" hypothesis.
    Arthritis and rheumatism, 2011, Volume: 63, Issue:12

    Topics: Aged; Cohort Studies; Colchicine; Crystallization; Female; Fenofibrate; Follow-Up Studies; Gout; Gou

2011
New treatments for gout.
    Joint bone spine, 2007, Volume: 74, Issue:4

    Topics: Allopurinol; Ascorbic Acid; Female; Fenofibrate; Gout; Gout Suppressants; Humans; Losartan; Male; Se

2007
Gout: beyond the stereotype.
    Hospital practice (1995), 1999, Jun-15, Volume: 34, Issue:6

    Topics: Aged; Algorithms; Allopurinol; Chronic Disease; Diagnosis, Differential; Female; Gout; Gout Suppress

1999
Losartan-induced angioedema.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:9

    Topics: Angioedema; Antihypertensive Agents; Gout; Humans; Hypertension; Losartan; Male; Middle Aged

1999
Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricemia and gout.
    Journal of hypertension, 2002, Volume: 20, Issue:2

    Topics: Antihypertensive Agents; Biphenyl Compounds; Gout; Humans; Hypertension; Irbesartan; Losartan; Tetra

2002