Page last updated: 2024-09-04

levofloxacin and Pneumococcal Infections

levofloxacin has been researched along with Pneumococcal Infections in 113 studies

Research

Studies (113)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (5.31)	18.2507
2000's	75 (66.37)	29.6817
2010's	25 (22.12)	24.3611
2020's	7 (6.19)	2.80

Authors

Authors	Studies
Appelbaum, PC; Credito, KL; DeWasse, B; Kosowska-Shick, K; McGhee, P; Pankuch, GA	1
Klugman, KP; Levin, BR; McGee, L; Rozen, DE	1
Kaatz, GW; LaPlante, KL; Lodise, TP; Rybak, MJ; Tsuji, B	1
Chang, CL; Jeong, J; Jeong, SH; Jung, HJ; Kim, HR; Kim, S; Lee, EY; Lee, JN; Shin, JH	1
Ardanuy, C; Bouza, E; Calatayud, L; Cercenado, E; Fenoll, A; Liñares, J; Martín, R; Pallares, R	1
Gould, CV; Metlay, JP; Shchepetov, M; Sniegowski, PD; Weiser, JN	1
Jorgensen, JH; Moore, MR; Ressner, RA	1
Chang, KY; Ho, YH; Hsieh, YC; Hsueh, PR; Huang, LM; Huang, YC; Lin, HC	1
Brown, SD; Critchley, IA; Jacobs, MR; Janjic, N; Tillotson, GS; Traczewski, MM	1
Aguilar, L; Biek, D; Fenoll, A; Giménez, MJ; Granizo, JJ; Robledo, O; Tarragó, D	1
Cai, L; Gilbert, GL; Kong, F; Oftadeh, S; Xiao, M; Xu, X; Zhou, F	1
Bajaksouzian, S; Biek, D; Critchley, IA; Good, CE; Jacobs, MR; Jones, RN; Sader, HS; Windau, AR	1
Inagaki, H; Kitamura, T; Komoriya, S; Nagamochi, M; Odagiri, T; Takahashi, H	1
Kim, EY; Kim, GR; Kim, SH; Shin, JH	1
Djilas, M; Marković, M; Milosavljević, B; Petrović, V; Ristić, M	1
Chai, X; Sun, H; Wei, S; Xu, G	1
Cacho Calvo, J; Martínez-Arce, R; Molina Arana, D; Pérez Abeledo, M; Ramos Blázquez, B; Sanz Moreno, JC; Zaragoza Vargas, G	1
Chen, HC; Chen, KJ; Chen, YP; Chong, YJ; Kang, EY; Lai, CC; Liu, L; Sun, MH; Wu, WC	1
Canut, A; Ibar-Bariain, M; Isla, A; Rodríguez-Gascón, A; Sanz-Moreno, JC; Solinís, MÁ	1
Chen, YH; Chen, YS; Cheng, SH; Hsueh, PR; Ko, WC; Lee, CM; Lee, WS; Lee, YL; Lin, CN; Lin, CY; Liu, CP; Lu, MC; Lu, PL; Shao, PL; Sheng, WH; Shi, ZY; Tang, HJ; Tsai, YT; Tseng, SH; Wang, FD; Wang, LS; Wu, TS; Yen, MY	1
Baek, JY; Chung, DR; Kang, CI; Kim, SH; Ko, KS; Lee, NY; Peck, KR; Song, JH	1
Bae, S; Kim, SH; Lee, S; Park, M	1
Allouche, S; Dabboussi, F; Hamze, M; Mallat, H	1
Caierão, J; d'Azevedo, PA; Dias, C; Matusiak, R; Mott, M; Pilger de Oliveira, KR; Rodrigues Perez, LR; Rosa da Cunha, G	1
Wang, H; Zhang, FF; Zhao, CJ	1
Adhikary, R; Bhattacharyya, A; Bishayi, B; Mahanti, S; Majhi, A	1
Adhikary, R; Bishayi, B; Mahanti, S; Majhi, A; Nandi, A	1
Hsueh, PR; Huang, YT; Liao, CH; Liu, CY; Tsai, HY	1
Cho, HC; Kim, HS; Kim, JS; Park, JY; Park, M; Song, W	1
Bergallo, C; Cooper, CA; Dartois, N; Dukart, G; Gandjini, H; Jasovich, A; Mallick, R; Oliva, ME; Tanaseanu, C; Teglia, O	1
Bush, K; Davies, TA; Evangelista, A; Goldschmidt, R; Sahm, D; Yee, YC	1
Davies, TA; Evangelista, AT; Goldschmidt, R; Sahm, DF; Yee, YC	1
Lister, PD	1
de Gouveia, L; du Plessis, M; Klugman, KP; von Gottberg, A; Wolter, N	1
Arija, V; Bejarano-Romero, F; Cliville-Guasch, X; de Diego, C; Gomez-Bertomeu, F; Ochoa-Gondar, O; Raga-Luria, X; Salsench, E; Vila-Corcoles, A	1
Kaneko, S; Satake, S; Sohma, M; Yokozawa, I	1
Alişkan, H; Güçlü, M; Husamettin, E; Serin, E; Yakar, T	1
Chang, LY; Hsieh, YC; Hsueh, PR; Huang, LM; Huang, YC; Lin, HC	1
Cohen, R; Grimprel, E	1
Araj, GF; Awar, GN; Baban, TA; Kanj, SS; Naba, MR; Tabbarah, ZA	1
Baba, S; Fujisawa, T; Harabuchi, Y; Ikeda, F; Kobayashi, T; Kurono, Y; Nishimura, T; Suzuki, K; Ubukata, K; Yamanaka, N	1
Colino, CI; Ferrer, A; Grau, S; Luque, S; Valle, M	1
Fujita, J; Haranaga, S; Higa, F; Nakasone, I; Sunagawa, S; Tateyama, M; Uno, T; Yamane, N	1
Green, K; Low, DE; McGeer, A; Melano, R; Patel, SN; Pillai, DR; Tyrrell, GJ	1
Dalla Costa, T; de Andrade, C; Tasso, L	1
Di Maggio, T; Mantengoli, E; Montagnani, F; Pallecchi, L; Pollini, S; Riccobono, E; Rossolini, GM	1
Aznar, J; Iraurgui, P; Torres, MJ	1
Carlos, CC; Chung, DR; Hsueh, PR; Kang, CI; Kim, SH; Peck, KR; Perera, J; So, TM; Song, JH; Thamlikitkul, V; Van, PH; Wang, H; Yasin, RM	1
Gomez-Gutierrez, P; Lupala, CS; Perez, JJ	1
Pessey, JJ	1
Soussy, CJ	1
Blosser-Middleton, RS; Critchley, IA; Jones, ME; Karginova, EA; Karlowsky, JA; Sahm, DF; Thornsberry, C	1
Ariano, RE; Harding, GK; Iacovides, H; Sun, S; Zelenitsky, SA	1
Critchley, IA; Evangelista, AT; Jones, ME; Karlowsky, JA; Noel, GJ; Sahm, DF; Thornsberry, C	1
Benjamin Jr, WH; Crain, MJ; Hollingshead, SK; Johnson, CN; Moser, SA; Nahm, MH; Waites, KB; Zheng, X	1
Anderson, KB; DiPersio, JR; File, TM; Low, DE; Tan, JS; Willey, BM	1
Garrison, MW	1
Itoh, Y; Kikuchi, K; Nakanishi, K; Nakao, S; Ohsaki, Y; Osanai, S; Saito, K; Sato, M; Tachibana, M; Takahashi, T; Toyoshima, E	1
Safdar, A	1
Blosser-Middleton, RS; Jones, ME; Karlowsky, JA; Sahm, DF; Thornsberry, C	1
Garrison, MW; Madaras-Kelly, KJ; Schimmels, JA	1
Low, DE	1
Schito, AM; Schito, GC	1
Marrie, TJ	1
Beall, B; Facklam, RR; Jorgensen, J; Klugman, KP; McGee, L; Pletz, MW; Whitney, CG	1
Brown, SD; Farrell, DJ; Morrissey, I	1
Ambrose, PG; Bhavnani, SM; Hammel, JP; Jones, RN	1
Beekmann, SE; Doern, GV; Heilmann, KP; Miller, NJ; Rice, CL; Richter, SS	1
Aguilar, L; Alkorta, M; Giménez, MJ; Pérez-Trallero, E; Vicente, D	1
Beall, B; Klugman, KP; McGee, L; Pletz, MW; Whitney, CG	1
Fuller, JD; Low, DE	1
Aguilar, L; Casal, J; Fenoll, A; Giménez, MJ; Lara, N; Sevillano, D; Tarragó, D	1
Gehanno, P; Pessey, JJ; Serrano, E	1
Ercibengoa, M; González, A; Larruskain, J; Marimón, JM; Pérez-Trallero, E	1
Hoban, DJ; Noreddin, AM; Zhanel, GG	1
Bush, K; Davies, TA; Evangelista, A; Goldschmidt, R; Sahm, DF; Yee, YC	1
Fukuda, Y; Mitsuyama, J; Takahata, M	1
Alou, L; del Carmen Ponte, M; Gracia, M; Huelves, L; López-Casla, MT; Martínez-Marín, C; Prieto, J; Sevillano, D; Soriano, F	1
Coll, P; Gurguí, M; Mateo, M; Mirelis, B; Miró, E; Navarro, F; Rebollo, M; Rivera, A	1
Adam, HJ; Hoban, DJ; Schurek, KN; Zhanel, GG	1
Cars, O; Odenholt, I	1
Benzonana, NA; Ozer, S; Oznur, AK	1
Adam, HJ; Baudry, TJ; Hoban, CJ; Hoban, DJ; Laing, NM; Nichol, KA; Schurek, KN; Zhanel, GG	1
Ambrose, PG; Anon, JB; Jones, RN; Kahn, JB; Paglia, M; Xiang, J	1
Denys, GA; Kays, MB; Lisek, CR	1
Alonso, R; Cisterna, R; Mateo, E	1
Chan, PK; Chau, SS; Cheuk, ES; Chi, F; Ip, M; Lai, RW; Ma, H	1
Bush, K; Dagan, R; Davies, TA; Leibovitz, E; McNeeley, DF; Noel, GJ	1
Cohen, C; de Gouveia, L; du Plessis, M; Govender, N; Hoffmann, R; Klugman, KP; Meiring, S; Mpembe, R; Quan, V; Schrag, S; Smith, AM; von Gottberg, A; Whitelaw, A; Wolter, N	1
Jones, RN; Pfaller, MA	2
Lacy, MK; Lu, W; Nicolau, DP; Nightingale, CH; Quintiliani, R; Tessier, PR; Xu, X	1
Block, SL; Chartrand, SA; Sanders, CC; Thomson, KS	1
Bauernfeind, A	1
Bui, KQ; Nicolau, DP; Nightingale, CH; Onyeji, CO; Owens, RC; Quintiliani, R	1
Bennett, SP; Wortmann, GW	1
Hershberger, E; Rybak, MJ	1
Rajacic, Z; Trampuz, A; Wenk, M; Zimmerli, W	1
Dobie, D; Hastings, M; Mahendra, P; Richardson, G; Tauro, S	1
Ambrose, PG; Grasela, DM	1
Bergogne-Bérézin, E	1
Alós, JI; Gómez-Garcés, JL; Oteo, J	1
Bui, KQ; Mattoes, H; McNabb, J; Nicolau, DP; Nightingale, CH; Quintiliani, R; Xuan, D; Zhong, M	1
Chan, RM; Cheng, VC; Ho, PL; Kwok, TK; Ng, TK; Tsang, KW; Tse, WS	1
Black, J; Chartrand, SA; Moland, ES; Thomson, KS	1
Jones, ME; Karlowsky, JA; Nealy, L; Sahm, DF; Thornsberry, C	1
Mendes, CM; Nicodemo, AC; Oplustil, CP; Sinto, S	1
Rossi, C; Sternon, J	1
Gorbach, SL; Ross, JJ; Worthington, MG	1
Drlica, K; Tillotson, GS; Zhao, X	1
Hutchinson, J	1
Bosso, JA; Enzweiler, KA; Friedrich, LV; Hoban, D; Wagner, D; White, RL	1

Reviews

5 review(s) available for levofloxacin and Pneumococcal Infections

Article	Year
[Update on levofloxacin in the management of acute sinusitis with risk of complications]. Presse medicale (Paris, France : 1983), 2002, Jun-15, Volume: 31, Issue:21 Pt 2 Topics: Abscess; Acute Disease; Anti-Infective Agents; Cellulitis; Clinical Trials as Topic; Disease Progression; Haemophilus Infections; Humans; Levofloxacin; Ofloxacin; Pneumococcal Infections; Risk Factors; Sinusitis	2002
[New microbiological data on the susceptibility of Pneumococci to levofloxacin]. Presse medicale (Paris, France : 1983), 2002, Jun-15, Volume: 31, Issue:21 Pt 2 Topics: Anti-Infective Agents; Drug Resistance, Microbial; France; Humans; Levofloxacin; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae	2002
Levofloxacin, a broad spectrum anti-infective: from Streptococcus pneumoniae to Pseudomonas aeruginosa. Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Humans; Italy; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Sensitivity and Specificity; Streptococcus pneumoniae	2004
A review of Streptococcus pneumoniae infection treatment failures associated with fluoroquinolone resistance. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Jul-01, Volume: 41, Issue:1 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae; Treatment Failure	2005
[Third and fourth generation fluoroquinolones]. Revue medicale de Bruxelles, 2001, Volume: 22, Issue:5 Topics: Administration, Oral; Anti-Infective Agents; Aza Compounds; Belgium; Biological Availability; Drug Monitoring; Drug Resistance; Fluoroquinolones; Gemifloxacin; Humans; Intestinal Absorption; Levofloxacin; Moxifloxacin; Naphthyridines; Ofloxacin; Patient Selection; Pneumococcal Infections; Quinolines; Respiratory Tract Infections; Streptococcus pneumoniae; Time Factors; Treatment Outcome	2001

Trials

4 trial(s) available for levofloxacin and Pneumococcal Infections

Article	Year
Integrated results of 2 phase 3 studies comparing tigecycline and levofloxacin in community-acquired pneumonia. Diagnostic microbiology and infectious disease, 2008, Volume: 61, Issue:3 Topics: Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Female; Gram-Negative Bacterial Infections; Haemophilus Infections; Humans; Levofloxacin; Liver Function Tests; Male; Middle Aged; Minocycline; Ofloxacin; Pneumococcal Infections; Pneumonia, Bacterial; Tigecycline; Treatment Outcome	2008
Experience with levofloxacin in a critical pathway for the treatment of community-acquired pneumonia. Chemotherapy, 2004, Volume: 50 Suppl 1 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents; Azithromycin; Cefuroxime; Community-Acquired Infections; Critical Pathways; Drug Therapy, Combination; Female; Humans; Levofloxacin; Longitudinal Studies; Male; Middle Aged; Ofloxacin; Oxygen Inhalation Therapy; Pneumococcal Infections; Pneumonia; Pneumonia, Bacterial; Treatment Outcome	2004
[Levofloxacin in the treatment of acute and bacteriologically documented sinusitis with high risk of complications]. Medecine et maladies infectieuses, 2005, Volume: 35, Issue:6 Topics: Acute Disease; Adolescent; Adult; Africa, Southern; Aged; Bacterial Infections; Female; France; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Male; Middle Aged; Moraxella catarrhalis; Moraxellaceae Infections; Ofloxacin; Pneumococcal Infections; Prospective Studies; Risk; Sinusitis; Staphylococcal Infections; Treatment Outcome; Tunisia	2005
Serial sinus aspirate samples during high-dose, short-course levofloxacin treatment of acute maxillary sinusitis. Diagnostic microbiology and infectious disease, 2007, Volume: 57, Issue:1 Topics: Acute Disease; Adult; Anti-Bacterial Agents; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Levofloxacin; Male; Maxillary Sinusitis; Microbial Sensitivity Tests; Middle Aged; Moraxella catarrhalis; Moraxellaceae Infections; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; Time Factors; Treatment Outcome	2007

Other Studies

104 other study(ies) available for levofloxacin and Pneumococcal Infections

Article	Year
Multistep resistance selection and postantibiotic-effect studies of the antipneumococcal activity of LBM415 compared to other agents. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Amidohydrolases; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Peptides; Pneumococcal Infections; Species Specificity; Streptococcus pneumoniae; Time Factors	2007
Fitness costs of fluoroquinolone resistance in Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mutation; Pneumococcal Infections; Streptococcus pneumoniae; Transformation, Bacterial	2007
Fluoroquinolone resistance in Streptococcus pneumoniae: area under the concentration-time curve/MIC ratio and resistance development with gatifloxacin, gemifloxacin, levofloxacin, and moxifloxacin. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Area Under Curve; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae	2007
Prevalence, characteristics, and molecular epidemiology of macrolide and fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae at five tertiary-care hospitals in Korea. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Anti-Bacterial Agents; Community-Acquired Infections; DNA, Bacterial; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Genes, Bacterial; Hospitals; Humans; Korea; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Molecular Epidemiology; Mutation; Ofloxacin; Pneumococcal Infections; Polymerase Chain Reaction; Prevalence; Reserpine; Respiratory Tract Infections; Retrospective Studies; Streptococcus pneumoniae	2007
Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Anti-Bacterial Agents; Clone Cells; Drug Resistance, Multiple, Bacterial; Electrophoresis, Polyacrylamide Gel; Erythromycin; Genes, Bacterial; Microbial Sensitivity Tests; Phenotype; Pneumococcal Infections; Serotyping; Spain; Streptococcus pneumoniae; Tetracycline Resistance	2007
Identifying mutator phenotypes among fluoroquinolone-resistant strains of Streptococcus pneumoniae using fluctuation analysis. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Anti-Bacterial Agents; DNA Repair; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Molecular Sequence Data; Mutation; Mutation, Missense; Phenotype; Pneumococcal Infections; Quinine; Streptococcus pneumoniae	2007
Activity of the Diaminopyrimidine AR-709 against recently collected multidrug-resistant isolates of invasive Streptococcus pneumoniae from North America. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Humans; Indoles; Microbial Sensitivity Tests; North America; Pneumococcal Infections; Pyrimidines; Streptococcus pneumoniae; Tetrahydrofolate Dehydrogenase	2008
Clonal spread of highly beta-lactam-resistant Streptococcus pneumoniae isolates in Taiwan. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Genotype; Humans; Microbial Sensitivity Tests; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; Taiwan	2008
Prevalence of serotype 19A Streptococcus pneumoniae among isolates from U.S. children in 2005-2006 and activity of faropenem. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Adolescent; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Drug Resistance, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Phenotype; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States	2008
In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11 Topics: Amoxicillin; Anti-Bacterial Agents; Cefotaxime; Ceftaroline; Cephalosporin Resistance; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae	2008
Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Proteins; Child, Preschool; DNA Transposable Elements; Drug Resistance, Bacterial; Erythromycin; Genotype; Humans; Macrolides; Microbial Sensitivity Tests; New South Wales; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae	2010
Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Communicable Diseases, Emerging; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States	2010
Design, Synthesis, and Biological Evaluation of Novel 7-[(3 aS,7 aS)-3 a-Aminohexahydropyrano[3,4- c]pyrrol-2(3 H)-yl]-8-methoxyquinolines with Potent Antibacterial Activity against Respiratory Pathogens. Journal of medicinal chemistry, 2018, 08-23, Volume: 61, Issue:16 Topics: Animals; Anti-Bacterial Agents; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; ERG1 Potassium Channel; Escherichia coli; Female; Humans; Macaca fascicularis; Male; Methicillin-Resistant Staphylococcus aureus; Mice, Inbred CBA; Microbial Sensitivity Tests; Pneumococcal Infections; Quinolines; Respiratory Tract Infections; Streptococcus pneumoniae	2018
Characteristics of Clonal Complex Changes and Quinolone Resistance-Determining Region Mutations of Levofloxacin-Resistant Microbial drug resistance (Larchmont, N.Y.), 2022, Volume: 28, Issue:5 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Pneumococcal Infections; Quinolones; Streptococcus pneumoniae	2022
Pneumococcal carriage in adults aged 50 years and older in outpatient health care facility during pandemic COVID-19 in Novi Sad, Serbia. PloS one, 2022, Volume: 17, Issue:10 Topics: Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Carrier State; Ceftriaxone; Child; COVID-19; Delivery of Health Care; Erythromycin; Female; Humans; Infant; Levofloxacin; Middle Aged; Nasopharynx; Outpatients; Pandemics; Penicillins; Pneumococcal Infections; Pneumococcal Vaccines; Serbia; Serogroup; Streptococcus pneumoniae; Tetracyclines; Trimethoprim, Sulfamethoxazole Drug Combination	2022
The Formation and Drug Resistance Mechanism of Biofilm for Streptococcus pneumoniae Infection in Severe Respiratory Patients. Cellular and molecular biology (Noisy-le-Grand, France), 2023, Jan-31, Volume: 69, Issue:1 Topics: Anti-Bacterial Agents; DNA Topoisomerase IV; Drug Resistance; Drug Resistance, Bacterial; Erythromycin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae	2023
[Evolution of the serotypes causing invasive pneumococcal disease along 2008-2022 in a Level 2 Public Hospital of the Madrid Region, in relation to their inclusion in different conjugate vaccines]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2023, Volume: 36, Issue:6 Topics: Anti-Bacterial Agents; Erythromycin; Hospitals, Public; Humans; Infant; Levofloxacin; Microbial Sensitivity Tests; Penicillins; Pneumococcal Infections; Pneumococcal Vaccines; Serogroup; Serotyping; Streptococcus pneumoniae; Vaccines, Conjugate	2023
Streptococcus pneumoniae endophthalmitis: clinical settings, antibiotic susceptibility, and visual outcomes. Scientific reports, 2021, 03-18, Volume: 11, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cataract; Cataract Extraction; Ceftriaxone; Cefuroxime; Corneal Ulcer; Endophthalmitis; Eye Enucleation; Eye Injuries; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Penicillins; Pneumococcal Infections; Retrospective Studies; Severity of Illness Index; Streptococcus pneumoniae; Taiwan; Tertiary Care Centers; Trabeculectomy; Treatment Outcome; Vancomycin; Vitrectomy	2021
Pharmacokinetic/pharmacodynamic evaluation of the antimicrobial therapy of pneumococcal invasive disease in adults in post-PCV13 vaccine period in Madrid, Spain. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2021, Volume: 40, Issue:10 Topics: Adult; Anti-Bacterial Agents; Cefotaxime; Clinical Trials as Topic; Humans; Levofloxacin; Penicillin G; Pneumococcal Infections; Pneumococcal Vaccines; Spain; Streptococcus pneumoniae	2021
Nationwide surveillance of antimicrobial resistance in invasive isolates of Streptococcus pneumoniae in Taiwan from 2017 to 2019. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2022, Volume: 55, Issue:2 Topics: Aged; Anti-Bacterial Agents; Ceftriaxone; Doripenem; Drug Resistance, Bacterial; Ertapenem; Humans; Levofloxacin; Linezolid; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae; Taiwan; Vancomycin	2022
Emergence of multidrug-resistant clones in levofloxacin-nonsusceptible Streptococcus pneumoniae isolates in Korea. Diagnostic microbiology and infectious disease, 2018, Volume: 91, Issue:3 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Female; Genes, Bacterial; Genotype; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Multilocus Sequence Typing; Mutation; Phenotype; Pneumococcal Infections; Prevalence; Republic of Korea; Serotyping; Streptococcus pneumoniae; Tertiary Care Centers	2018
High prevalence of multiresistance in levofloxacin-nonsusceptible Streptococcus pneumoniae isolates in Korea. Diagnostic microbiology and infectious disease, 2013, Volume: 76, Issue:2 Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Genetic Loci; Humans; Levofloxacin; Microbial Sensitivity Tests; Pneumococcal Infections; Pneumococcal Vaccines; Prevalence; Republic of Korea; Serotyping; Streptococcus pneumoniae; Vaccines, Conjugate	2013
Prevalence of first-step mutants among levofloxacin-susceptible isolates of Streptococcus pneumoniae in north Lebanon. Journal of chemotherapy (Florence, Italy), 2013, Volume: 25, Issue:6 Topics: Blood; Drug Resistance, Bacterial; Ear; Eye; Fluoroquinolones; Humans; Lebanon; Levofloxacin; Lung; Microbial Sensitivity Tests; Mutation; Nose; Pneumococcal Infections; Prevalence; Streptococcus pneumoniae	2013
Susceptibility profiles and correlation with pneumococcal serotypes soon after implementation of the 10-valent pneumococcal conjugate vaccine in Brazil. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 20 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Brazil; Child; Child, Preschool; Clindamycin; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Infant; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Middle Aged; Pneumococcal Infections; Pneumococcal Vaccines; Serotyping; Streptococcus pneumoniae; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult	2014
[Fluoroquinolone resistance determining region mutation in Streptococcus pneumonia isolates]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2013, Volume: 36, Issue:12 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genes, Bacterial; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Pneumococcal Infections; Polymerase Chain Reaction; Streptococcus pneumoniae; Young Adult	2013
Levofloxacin-ceftriaxone combination attenuates lung inflammation in a mouse model of bacteremic pneumonia caused by multidrug-resistant Streptococcus pneumoniae via inhibition of cytolytic activities of pneumolysin and autolysin. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:9 Topics: Animals; Anti-Bacterial Agents; Bacteremia; Bacterial Proteins; Bronchoalveolar Lavage Fluid; Ceftriaxone; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Levofloxacin; Male; Mice; Mice, Inbred BALB C; N-Acetylmuramoyl-L-alanine Amidase; Pneumococcal Infections; Pneumonia; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Streptolysins; Virulence; Virulence Factors	2014
In vitro susceptibility of a penicillin-resistant and tolerable isolate of Streptococcus pneumoniae to combination therapy. Journal of infection in developing countries, 2015, Jul-30, Volume: 9, Issue:7 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Ceftriaxone; Drug Synergism; Drug Tolerance; Humans; Levofloxacin; Microbial Sensitivity Tests; Microbial Viability; Pneumococcal Infections; Streptococcus pneumoniae	2015
In vitro synergy of penicillin, ceftriaxone and levofloxacin against serotype 19A Streptococcus pneumoniae. International journal of antimicrobial agents, 2015, Volume: 46, Issue:6 Topics: Anti-Bacterial Agents; Ceftriaxone; Drug Synergism; Humans; Levofloxacin; Microbial Sensitivity Tests; Penicillins; Pneumococcal Infections; Serogroup; Streptococcus pneumoniae	2015
Novel Levofloxacin-Resistant Multidrug-Resistant Streptococcus pneumoniae Serotype 11A Isolates, South Korea. Emerging infectious diseases, 2016, Volume: 22, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Pneumococcal Infections; Republic of Korea; Serogroup; Streptococcus pneumoniae	2016
Effects of the 7-valent pneumococcal conjugate vaccine on U.S. levofloxacin-resistant Streptococcus pneumoniae. Microbial drug resistance (Larchmont, N.Y.), 2008, Volume: 14, Issue:3 Topics: Amino Acid Substitution; Anti-Bacterial Agents; Base Sequence; Chi-Square Distribution; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Heptavalent Pneumococcal Conjugate Vaccine; Humans; Levofloxacin; Meningococcal Vaccines; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pneumococcal Vaccines; Regression Analysis; Serotyping; Streptococcus pneumoniae; United States	2008
Decline in the prevalence of pandemic clones Spain23F-1 and Spain9V-3 among US fluoroquinolone-resistant Streptococcus pneumoniae TRUST Surveillance isolates since 2001. Postgraduate medicine, 2008, Volume: 120, Issue:3 Suppl 1 Topics: Clone Cells; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Population Surveillance; Prevalence; Streptococcus pneumoniae; United States	2008
Pharmacodynamics of levofloxacin against characterized ciprofloxacin-resistant Streptococcus pneumoniae. Postgraduate medicine, 2008, Volume: 120, Issue:3 Suppl 1 Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; United States	2008
Molecular characterization of emerging non-levofloxacin-susceptible pneumococci isolated from children in South Africa. Journal of clinical microbiology, 2009, Volume: 47, Issue:5 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; Carrier State; Child; Child, Preschool; Cluster Analysis; DNA Fingerprinting; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genotype; Humans; Infant; Infant, Newborn; Levofloxacin; Microbial Sensitivity Tests; Mutation, Missense; Ofloxacin; Pneumococcal Infections; Sequence Analysis, DNA; Serotyping; South Africa; Streptococcus pneumoniae; Tuberculosis	2009
Drug-resistance in Streptococcus pneumoniae isolates among Spanish middle aged and older adults with community-acquired pneumonia. BMC infectious diseases, 2009, Mar-25, Volume: 9 Topics: Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Blood; Cefotaxime; Community-Acquired Infections; Drug Resistance, Multiple, Bacterial; Erythromycin; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Oxacillin; Pneumococcal Infections; Serotyping; Spain; Sputum; Streptococcus pneumoniae	2009
[Epidemiological study of levofloxacin-resistant Streptococcus pneumoniae isolated from 2003 through 2006 in Japan]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2009, Volume: 83, Issue:2 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Epidemiologic Methods; Humans; Japan; Levofloxacin; Middle Aged; Ofloxacin; Pneumococcal Infections; Software; Streptococcus pneumoniae	2009
A recent evaluation of empirical cephalosporin treatment and antibiotic resistance of changing bacterial profiles in spontaneous bacterial peritonitis. Digestive diseases and sciences, 2010, Volume: 55, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ascitic Fluid; Bacterial Infections; Cefepime; Cefotaxime; Cephalosporins; Drug Resistance, Bacterial; Enterococcus; Escherichia coli Infections; Female; Humans; Infusions, Intravenous; Klebsiella Infections; Klebsiella pneumoniae; Leukocyte Count; Levofloxacin; Liver Cirrhosis; Male; Microbial Sensitivity Tests; Middle Aged; Neutrophils; Ofloxacin; Peritonitis; Pneumococcal Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections	2010
Circulation of international clones of levofloxacin non-susceptible Streptococcus pneumoniae in Taiwan. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2010, Volume: 16, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Anti-Bacterial Agents; Base Sequence; Child; Child, Preschool; Community-Acquired Infections; DNA Gyrase; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Epidemiology; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Polymerase Chain Reaction; Risk Factors; Sequence Analysis, Protein; Serotyping; Streptococcus pneumoniae; Taiwan; Young Adult	2010
[Levofloxacin in children]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17 Suppl 4 Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Child; Community-Acquired Infections; Humans; Levofloxacin; Mycoplasma pneumoniae; Ofloxacin; Otitis Media; Pneumococcal Infections; Pneumonia; Sinusitis; Staphylococcus aureus; Streptococcus pneumoniae	2010
Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in Lebanon: a report of three cases. Journal of infection and public health, 2010, Volume: 3, Issue:3 Topics: Aged; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Clarithromycin; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Lebanon; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Vancomycin	2010
[Mutant prevention concentrations of garenoxacin against Streptococcus pneumoniae isolates from otorhinolaryngological infections]. The Japanese journal of antibiotics, 2010, Volume: 63, Issue:4 Topics: Anti-Bacterial Agents; Aza Compounds; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Mutation; Ofloxacin; Otorhinolaryngologic Diseases; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae	2010
Levofloxacin weight-adjusted dosing and pharmacokinetic disposition in a morbidly obese patient. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:7 Topics: Anti-Bacterial Agents; Body Weight; Humans; Infusions, Intravenous; Levofloxacin; Middle Aged; Obesity, Morbid; Ofloxacin; Pneumococcal Infections	2011
Comparison of drug sensitivity and genotypes of clinically isolated strains of levofloxacin-resistant Streptococcus pneumoniae obtained from Okinawa Island, the Japanese main island and Hong Kong. The Journal of antibiotics, 2011, Volume: 64, Issue:8 Topics: Anti-Bacterial Agents; Bacterial Proteins; Cluster Analysis; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genotype; Hong Kong; Humans; Japan; Levofloxacin; Microbial Sensitivity Tests; Molecular Typing; Ofloxacin; Pneumococcal Infections; Polymerase Chain Reaction; Sequence Analysis, DNA; Streptococcus pneumoniae	2011
Susceptibility of Streptococcus pneumoniae to fluoroquinolones in Canada. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:8 Topics: Anti-Bacterial Agents; Aza Compounds; Binding Sites; Canada; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae	2011
Pharmacokinetic/pharmacodynamic modelling of the bactericidal activity of free lung concentrations of levofloxacin and gatifloxacin against Streptococcus pneumoniae. International journal of antimicrobial agents, 2011, Volume: 38, Issue:4 Topics: Anti-Bacterial Agents; Area Under Curve; Culture Media; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Lung; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae	2011
Antipneumococcal activity of ulifloxacin compared to levofloxacin and ciprofloxacin. Journal of chemotherapy (Florence, Italy), 2011, Volume: 23, Issue:5 Topics: Anti-Bacterial Agents; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Italy; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Pneumococcal Infections; Streptococcus pneumoniae	2011
Molecular epidemiology of fluoroquinolone resistance in invasive clinical isolates of Streptococcus pneumoniae in Seville. Enfermedades infecciosas y microbiologia clinica, 2012, Volume: 30, Issue:4 Topics: Adult; Anti-Bacterial Agents; Bacterial Proteins; Biological Transport; DNA Gyrase; DNA Mutational Analysis; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Fluoroquinolones; Humans; Infant; Job Syndrome; Levofloxacin; Male; Microbial Sensitivity Tests; Norfloxacin; Ofloxacin; Pneumococcal Infections; Reserpine; Serotyping; Spain; Streptococcus pneumoniae	2012
Association of levofloxacin resistance with mortality in adult patients with invasive pneumococcal diseases: a post hoc analysis of a prospective cohort. Infection, 2013, Volume: 41, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Bacterial; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumococcal Infections; Population Surveillance; Prospective Studies; Risk Factors; Streptococcus pneumoniae; Treatment Outcome	2013
Molecular determinants of the bacterial resistance to fluoroquinolones: a computational study. Current computer-aided drug design, 2013, Volume: 9, Issue:2 Topics: Acinetobacter; Acinetobacter Infections; Anti-Bacterial Agents; Aza Compounds; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Molecular Docking Simulation; Moxifloxacin; Pneumococcal Infections; Point Mutation; Quinolines; Streptococcus pneumoniae	2013
Phenotypic and genotypic analysis of levofloxacin-resistant clinical isolates of Streptococcus pneumoniae collected in 13 countries during 1999-2000. International journal of antimicrobial agents, 2002, Volume: 20, Issue:2 Topics: Anti-Infective Agents; Asia; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Europe; Genotype; Humans; Levofloxacin; Mexico; Microbial Sensitivity Tests; Mutation; Ofloxacin; Phenotype; Pneumococcal Infections; Sequence Analysis, DNA; South Africa; Streptococcus pneumoniae	2002
AUC(0-t)/MIC is a continuous index of fluoroquinolone exposure and predictive of antibacterial response for Streptococcus pneumoniae in an in vitro infection model. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:4 Topics: Anti-Infective Agents; Area Under Curve; Aza Compounds; Culture Media; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Predictive Value of Tests; Quinolines; Streptococcus pneumoniae	2003
Susceptibilities to levofloxacin in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis clinical isolates from children: results from 2000-2001 and 2001-2002 TRUST studies in the United States. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Azithromycin; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacterial Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Lactams; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Moraxella catarrhalis; Ofloxacin; Pneumococcal Infections; Prospective Studies; Respiratory Tract Infections; Streptococcus pneumoniae; Trimethoprim, Sulfamethoxazole Drug Combination; United States	2003
Genetic relatedness of levofloxacin-nonsusceptible Streptococcus pneumoniae isolates from North America. Journal of clinical microbiology, 2003, Volume: 41, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Capsules; Bacterial Typing Techniques; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Levofloxacin; Microbial Sensitivity Tests; North America; Ofloxacin; Pneumococcal Infections; Sequence Analysis, DNA; Serotyping; Streptococcus pneumoniae	2003
Emergence of levofloxacin-resistant pneumococci in immunocompromised adults after therapy for community-acquired pneumonia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Aug-01, Volume: 37, Issue:3 Topics: Adult; Anti-Infective Agents; Community-Acquired Infections; Drug Resistance, Microbial; Humans; Immunocompromised Host; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2003
Comparative antimicrobial activity of levofloxacin and ciprofloxacin against Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:3 Topics: Anti-Bacterial Agents; Area Under Curve; Ciprofloxacin; Humans; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae	2003
Alterations in penicillin binding protein gene of Streptococcus pneumoniae and their correlation with susceptibility patterns. International journal of antimicrobial agents, 2003, Volume: 22, Issue:2 Topics: Aminoacyltransferases; Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; Carrier Proteins; Clarithromycin; Drug Resistance, Bacterial; Genes, Bacterial; Hexosyltransferases; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Mutation; Ofloxacin; Penicillin G; Penicillin Resistance; Penicillin-Binding Proteins; Peptidyl Transferases; Pneumococcal Infections; Streptococcus pneumoniae; Thienamycins	2003
Efficacy of vancomycin plus levofloxacin combination therapy for refractory pericarditis due to multiresistant Streptococcus pneumoniae. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2003, Volume: 7, Issue:4 Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Levofloxacin; Male; Ofloxacin; Pericarditis; Pneumococcal Infections; Streptococcus pneumoniae; Vancomycin	2003
The activity of levofloxacin and other antimicrobials against clinical isolates of Streptococcus pneumoniae collected worldwide during 1999-2002. Diagnostic microbiology and infectious disease, 2003, Volume: 47, Issue:4 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Global Health; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Respiratory Tract Infections; Sensitivity and Specificity; Streptococcus pneumoniae	2003
In vitro pharmacodynamic activity of gatifloxacin, gemifloxacin, moxifloxacin and levofloxacin against Streptococcus pneumoniae containing specific mutations in DNA gyrase and topoisomerase IV. Diagnostic microbiology and infectious disease, 2003, Volume: 47, Issue:4 Topics: Analysis of Variance; Aza Compounds; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Pharmacogenetics; Pneumococcal Infections; Probability; Quinolines; Reference Values; Regression Analysis; Sensitivity and Specificity; Streptococcus pneumoniae	2003
Quinolone resistance among pneumococci: therapeutic and diagnostic implications. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, May-15, Volume: 38 Suppl 4 Topics: Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2004
Levofloxacin-resistant invasive Streptococcus pneumoniae in the United States: evidence for clonal spread and the impact of conjugate pneumococcal vaccine. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:9 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Mutation; Ofloxacin; Pneumococcal Infections; Pneumococcal Vaccines; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Serotyping; Streptococcus pneumoniae; United States; Vaccines, Conjugate	2004
Prevalence and molecular analysis of macrolide and fluoroquinolone resistance among isolates of Streptococcus pneumoniae collected during the 2000-2001 PROTEKT US Study. Journal of clinical microbiology, 2004, Volume: 42, Issue:11 Topics: Anti-Bacterial Agents; Bacterial Proteins; Community-Acquired Infections; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Humans; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Population Surveillance; Prevalence; Respiratory Tract Infections; Streptococcus pneumoniae; United States	2004
Relationship between increased levofloxacin use and decreased susceptibility of Streptococcus pneumoniae in the United States. Diagnostic microbiology and infectious disease, 2005, Volume: 51, Issue:1 Topics: Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae	2005
The molecular epidemiology of Streptococcus pneumoniae with quinolone resistance mutations. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Jan-15, Volume: 40, Issue:2 Topics: Anti-Bacterial Agents; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Humans; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pneumococcal Infections; Population Surveillance; Serotyping; Streptococcus pneumoniae; Time Factors; United States	2005
In vivo activity of gemifloxacin, moxifloxacin and levofloxacin against pneumococci with gyrA and parC point mutations in a sepsis mouse model measured with the all or nothing mortality end-point. International journal of antimicrobial agents, 2005, Volume: 25, Issue:2 Topics: Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Models, Animal; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gemifloxacin; Levofloxacin; Mice; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Point Mutation; Quinolines; Sepsis; Streptococcus pneumoniae; Treatment Outcome	2005
Interspecies recombination in type II topoisomerase genes is not a major cause of fluoroquinolone resistance in invasive Streptococcus pneumoniae isolates in the United States. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:2 Topics: Anti-Bacterial Agents; DNA Topoisomerases, Type II; Drug Resistance, Bacterial; Fluoroquinolones; Gene Transfer, Horizontal; Levofloxacin; Ofloxacin; Pneumococcal Infections; Recombination, Genetic; Streptococcus pneumoniae; United States; Viridans Streptococci	2005
Specific antibodies, levofloxacin, and modulation of capsule-associated virulence in Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:7 Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Antibody Specificity; Area Under Curve; Bacterial Capsules; Female; Humans; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; Virulence	2005
In vivo development of high-level fluoroquinolone resistance in Streptococcus pneumoniae in chronic obstructive pulmonary disease. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Aug-15, Volume: 41, Issue:4 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Polymerase Chain Reaction; Pulmonary Disease, Chronic Obstructive; Serotyping; Streptococcus pneumoniae	2005
Comparison of gatifloxacin and levofloxacin administered at various dosing regimens to hospitalised patients with community-acquired pneumonia: pharmacodynamic target attainment study using North American surveillance data for Streptococcus pneumoniae. International journal of antimicrobial agents, 2005, Volume: 26, Issue:2 Topics: Adult; Aged; Community-Acquired Infections; Drug Administration Schedule; Epidemiologic Methods; Fluoroquinolones; Gatifloxacin; Hospitalization; Humans; Levofloxacin; Middle Aged; Monte Carlo Method; Ofloxacin; Pneumococcal Infections; Predictive Value of Tests; Streptococcus pneumoniae	2005
Infrequent occurrence of single mutations in topoisomerase IV and DNA gyrase genes among US levofloxacin-susceptible clinical isolates of Streptococcus pneumoniae from nine institutions (1999-2003). The Journal of antimicrobial chemotherapy, 2006, Volume: 57, Issue:3 Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Levofloxacin; Microbial Sensitivity Tests; Mutation; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; United States	2006
Pharmacodynamic evaluation of tosufloxacin against Streptococcus pneumoniae in an in vitro model simulating serum concentration. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2006, Volume: 12, Issue:1 Topics: Anti-Bacterial Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Mutation; Naphthyridines; Ofloxacin; Pneumococcal Infections; Serum Bactericidal Test; Streptococcus pneumoniae; Treatment Outcome	2006
Correlation between in vitro and in vivo activity of levofloxacin and moxifloxacin against pneumococcal strains with different susceptibilities to fluoroquinolones. International journal of antimicrobial agents, 2006, Volume: 27, Issue:4 Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Colony Count, Microbial; Disease Models, Animal; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Male; Mice; Models, Biological; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae; Survival Analysis	2006
Superantigen gene profile, emm type and antibiotic resistance genes among group A streptococcal isolates from Barcelona, Spain. Journal of medical microbiology, 2006, Volume: 55, Issue:Pt 8 Topics: Alleles; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Resistance; Erythromycin; Genes, Bacterial; Genetic Variation; Hospitals; Humans; Levofloxacin; Medical Records; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Ofloxacin; Pneumococcal Infections; Retrospective Studies; Spain; Species Specificity; Streptococcus pyogenes; Superantigens; Tetracycline; Urban Population	2006
Call for the international adoption of microbiological breakpoints for fluoroquinolones and Streptococcus pneumoniae. International journal of antimicrobial agents, 2006, Volume: 28, Issue:3 Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; North America; Ofloxacin; Pneumococcal Infections; Point Mutation; Streptococcus pneumoniae	2006
Pharmacodynamics of moxifloxacin and levofloxacin against Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae and Escherichia coli: simulation of human plasma concentrations after intravenous dosage in an in vitro kinetic model. The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:5 Topics: Animals; Anti-Infective Agents; Area Under Curve; Aza Compounds; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Horses; Humans; Injections, Intravenous; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae	2006
[Antibiotic resistance in Streptococcus pneumoniae strains isolated from sterile body sites]. Mikrobiyoloji bulteni, 2006, Volume: 40, Issue:3 Topics: Anti-Bacterial Agents; Bacteremia; Cerebrospinal Fluid; Dacryocystitis; Drug Resistance, Bacterial; Ear, Middle; Erythromycin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Pleural Effusion; Pneumococcal Infections; Streptococcus pneumoniae; Synovial Fluid; Wound Infection	2006
Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aza Compounds; Bacterial Proteins; Canada; Child; Child, Preschool; Ciprofloxacin; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Genotype; Humans; Infant; Infant, Newborn; Levofloxacin; Middle Aged; Moxifloxacin; Naphthyridines; Ofloxacin; Pneumococcal Infections; Quinolines; Serotyping; Streptococcus pneumoniae	2007
Comparative in vitro and bactericidal activities of telithromycin against penicillin-nonsusceptible, levofloxacin-resistant, and macrolide-resistant Streptococcus pneumoniae by time-kill methodology. International journal of antimicrobial agents, 2007, Volume: 29, Issue:3 Topics: Anti-Bacterial Agents; Humans; In Vitro Techniques; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae	2007
Detection of parC mutations in Streptococcus pneumoniae by Real-time PCR and Taqman-MGB probes. Journal of microbiological methods, 2007, Volume: 69, Issue:1 Topics: Anti-Infective Agents; Aspartic Acid; Codon; DNA Mutational Analysis; DNA Topoisomerase IV; Drug Resistance, Bacterial; Levofloxacin; Mutation; Ofloxacin; Oligonucleotide Probes; Pneumococcal Infections; Polymerase Chain Reaction; Serine; Streptococcus pneumoniae; Taq Polymerase	2007
Longitudinally tracking fluoroquinolone resistance and its determinants in penicillin-susceptible and -nonsusceptible Streptococcus pneumoniae isolates in Hong Kong, 2000 to 2005. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Fluoroquinolones; Hong Kong; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae	2007
Characterization and dynamics of middle ear fluid and nasopharyngeal isolates of Streptococcus pneumoniae from 12 children treated with levofloxacin. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1 Topics: Acute Disease; Anti-Bacterial Agents; Child, Preschool; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Infant; Levofloxacin; Nasopharynx; Ofloxacin; Otitis Media with Effusion; Pneumococcal Infections; Streptococcus pneumoniae	2008
Emergence of levofloxacin-non-susceptible Streptococcus pneumoniae and treatment for multidrug-resistant tuberculosis in children in South Africa: a cohort observational surveillance study. Lancet (London, England), 2008, Mar-29, Volume: 371, Issue:9618 Topics: Adolescent; Anti-Bacterial Agents; Antitubercular Agents; Child; Child, Preschool; Cross Infection; Cross-Sectional Studies; Drug Resistance, Bacterial; Female; Humans; Infant; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Population Surveillance; Rifampin; Risk Factors; South Africa; Statistics, Nonparametric; Streptococcus pneumoniae; Tuberculosis, Multidrug-Resistant; World Health Organization	2008
Comparative antistreptococcal activity of two newer fluoroquinolones, levofloxacin and sparfloxacin. Diagnostic microbiology and infectious disease, 1997, Volume: 29, Issue:3 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Ofloxacin; Pneumococcal Infections; Quinolones; Streptococcal Infections; Streptococcus; Streptococcus pneumoniae	1997
Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:3 Topics: Ampicillin; Ampicillin Resistance; Anti-Infective Agents; Ciprofloxacin; Culture Media; Drug Resistance, Microbial; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Ofloxacin; Penicillins; Pneumococcal Infections	1999
In-vitro activity of levofloxacin against Streptococcus pneumoniae with various levels of penicillin resistance. The Journal of antimicrobial chemotherapy, 1999, Volume: 43 Suppl C Topics: Anti-Bacterial Agents; Anti-Infective Agents; Child; Humans; Lactams; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae	1999
Pharmacodynamics of levofloxacin and ofloxacin against Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 1999, Volume: 43 Suppl C Topics: Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae	1999
Comparative efficacies of levofloxacin and ciprofloxacin against Streptococcus pneumoniae in a mouse model of experimental septicaemia. International journal of antimicrobial agents, 1999, Volume: 12, Issue:2 Topics: Acute Kidney Injury; Administration, Cutaneous; Animals; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Disease Models, Animal; Drug Resistance, Microbial; Humans; Lethal Dose 50; Levofloxacin; Mice; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae; Survival Analysis; Time Factors; Uranyl Nitrate	1999
Fatal meningitis due to levofloxacin-resistant Streptococcus pneumoniae. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 29, Issue:6 Topics: Anti-Infective Agents; Drug Resistance, Microbial; Fatal Outcome; Humans; Levofloxacin; Male; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae	1999
Activities of trovafloxacin, gatifloxacin, clinafloxacin, sparfloxacin, levofloxacin, and ciprofloxacin against penicillin-resistant Streptococcus pneumoniae in an in vitro infection model. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Anti-Infective Agents; Blood Coagulation; Ciprofloxacin; Fibrin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae	2000
Pharmacokinetics and pharmacodynamics of levofloxacin against Streptococcus pneumoniae and Staphylococcus aureus in human skin blister fluid. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:5 Topics: Anti-Infective Agents; Blister; Body Fluids; Granulocytes; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Skin Diseases, Bacterial; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae; Time Factors	2000
Recurrent penicillin-resistant pneumococcal sepsis after matched unrelated donor (MUD) transplantation for refractory T cell lymphoma. Bone marrow transplantation, 2000, Volume: 26, Issue:9 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bone Marrow Transplantation; Carmustine; Cefotaxime; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Cytomegalovirus Infections; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Idarubicin; Immunocompromised Host; Immunosuppressive Agents; Levofloxacin; Lymphoma, T-Cell; Male; Melphalan; Ofloxacin; Penicillin Resistance; Pneumococcal Infections; Prednisone; Recurrence; Rifampin; Splenectomy; Streptococcus pneumoniae; Transplantation Conditioning; Vincristine	2000
The use of Monte Carlo simulation to examine pharmacodynamic variance of drugs: fluoroquinolone pharmacodynamics against Streptococcus pneumoniae. Diagnostic microbiology and infectious disease, 2000, Volume: 38, Issue:3 Topics: Anti-Infective Agents; Area Under Curve; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Monte Carlo Method; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae	2000
[Resistance and new antibiotic strategies. The other new molecules]. Presse medicale (Paris, France : 1983), 2000, Dec-02, Volume: 29, Issue:37 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Outer Membrane Proteins; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Lactams; Levofloxacin; Neutropenia; Ofloxacin; Peptides; Pneumococcal Infections	2000
Antimicrobial resistance of Streptococcus pneumoniae isolates in 1999 and 2000 in Madrid, Spain: a multicentre surveillance study. The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:2 Topics: Anti-Infective Agents; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Spain; Streptococcus pneumoniae	2001
Streptococcus pneumoniae response to repeated moxifloxacin or levofloxacin exposure in a rabbit tissue cage model. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:3 Topics: Animals; Anti-Infective Agents; Aza Compounds; Disease Models, Animal; Female; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Rabbits; Streptococcus pneumoniae	2001
Macrolide and fluoroquinolone (levofloxacin) resistances among Streptococcus pneumoniae strains: significant trends from the SENTRY Antimicrobial Surveillance Program (North America, 1997-1999). Journal of clinical microbiology, 2000, Volume: 38, Issue:11 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Humans; Levofloxacin; Macrolides; North America; Ofloxacin; Pneumococcal Infections; Population Surveillance; Streptococcus pneumoniae	2000
Risk factors for acquisition of levofloxacin-resistant Streptococcus pneumoniae: a case-control study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Mar-01, Volume: 32, Issue:5 Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Case-Control Studies; Drug Resistance, Microbial; Female; Hong Kong; Humans; Levofloxacin; Lung Diseases, Obstructive; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pneumococcal Infections; Retrospective Studies; Risk Factors; Streptococcus pneumoniae	2001
Activity of oral agents against pediatric isolates of Streptococcus pneumoniae. Diagnostic microbiology and infectious disease, 2001, Volume: 39, Issue:3 Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Child; Child, Preschool; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Lactams; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Pneumococcal Infections; Quinolines; Streptococcus pneumoniae	2001
Trends in ciprofloxacin nonsusceptibility and levofloxacin resistance among Streptococcus pneumoniae isolates in North America. Journal of clinical microbiology, 2001, Volume: 39, Issue:7 Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; North America; Ofloxacin; Pneumococcal Infections; Population Surveillance; Streptococcus pneumoniae	2001
In vitro activity of fluoroquinolones (gatifloxacin, levofloxacin and trovafloxacin) and seven other antibiotics against Streptococcus pneumoniae. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2001, Volume: 5, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Gatifloxacin; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae	2001
Resistance of Streptococcus pneumoniae to fluoroquinolones--United States, 1995-1999. MMWR. Morbidity and mortality weekly report, 2001, Sep-21, Volume: 50, Issue:37 Topics: Anti-Infective Agents; Drug Resistance, Microbial; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae; United States	2001
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. The New England journal of medicine, 2002, Jul-04, Volume: 347, Issue:1 Topics: Aged; Anti-Infective Agents; Bacteremia; Drug Resistance, Bacterial; Fatal Outcome; Humans; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Treatment Failure	2002
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. The New England journal of medicine, 2002, Jul-04, Volume: 347, Issue:1 Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Levofloxacin; Ofloxacin; Pneumococcal Infections; Streptococcus pneumoniae	2002
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. The New England journal of medicine, 2002, Jul-04, Volume: 347, Issue:1 Topics: Anti-Infective Agents; Canada; Drug Resistance, Bacterial; Drug Utilization; Hospitals; Humans; Levofloxacin; Ofloxacin; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae	2002
Comparative activity of gatifloxacin and other antibiotics against 4009 clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000. Diagnostic microbiology and infectious disease, 2002, Volume: 43, Issue:3 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Ceftriaxone; Child; Ciprofloxacin; Female; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Penicillin Resistance; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae; United States	2002