Page last updated: 2024-10-17

lactic acid and HIV

lactic acid has been researched along with HIV in 11 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.

Research Excerpts

ExcerptRelevanceReference
" polylactic acid (PLA) for the treatment of facial lipoatrophy in HIV-infected adults."5.17Polylactic acid vs. polyacrylamide hydrogel for treatment of facial lipoatrophy: a randomized controlled trial [Agence Nationale de Recherches sur le SIDA et les Hépatites Virales (ANRS) 132 SMILE]. ( Bouchaud, O; Carbonnel, E; Dolivo, M; Girard, PM; Lafaurie, M; Loze, B; Madelaine, I; May, T; Molina, JM; Porcher, R, 2013)
"Perinatal antiretroviral (ARV) exposure has been related to hyperlactatemia and lactic acidosis in infants born to HIV-infected mothers."3.78Hyperlactatemia and in utero exposure to antiretrovirals: is the control group the clue? ( Arranz, JA; Espiau, M; Figueras, C; Martín-Nalda, A; Martínez-Gómez, X; Melendo, S; Riudor, E; Soler-Palacín, P, 2012)
"Lactic acidosis in patients infected with the human immunodeficiency virus was initially identified as a rare complication of therapy with nucleoside analog reverse transcriptase inhibitors (NRTIs)."3.72Lactic acidemia in infection with human immunodeficiency virus. ( Carr, A, 2003)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hearps, AC1
Tyssen, D1
Srbinovski, D1
Bayigga, L1
Diaz, DJD1
Aldunate, M1
Cone, RA1
Gugasyan, R1
Anderson, DJ1
Tachedjian, G1
Lafaurie, M1
Dolivo, M1
Girard, PM1
May, T1
Bouchaud, O1
Carbonnel, E1
Madelaine, I1
Loze, B1
Porcher, R1
Molina, JM1
Lee, J2
Tan, CY1
Lee, SK2
Kim, YH1
Lee, KY2
Soler-Palacín, P1
Martín-Nalda, A1
Martínez-Gómez, X1
Melendo, S1
Riudor, E1
Arranz, JA1
Espiau, M1
Figueras, C1
Choi, S1
Kumar, P1
Pattnaik, G1
Sinha, B1
Mukherjee, B1
Ghosh, S1
Basak, S1
Mondal, S1
Bera, T1
Carr, A1
Sharpe, S1
Hanke, T1
Tinsley-Bown, A1
Dennis, M1
Dowall, S1
McMichael, A1
Cranage, M1
Haugaard, SB1
Andersen, O1
Dela, F1
Holst, JJ1
Storgaard, H1
Fenger, M1
Iversen, J1
Madsbad, S1
Treacy, PJ1
Goldberg, DJ1
Chen, CH1
Cheng, YC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Comparative, Multicenter, Patient-blinded Trial of the Safety and Efficacy of Intradermal Injections of Polylactic Acid (Newfill TM) Versus Polyacrylamid Gel (Eutrophill) in the Treatment of Facial Lipoatrophy in HIV-infected Patients ANRS 132[NCT00383734]Phase 3148 participants (Actual)Interventional2006-12-31Completed
The Effect of Low-Dose Human Growth Hormone Therapy in HIV Infected Patients on Highly Active Antiretroviral Therapy (HAART)[NCT00119769]Phase 446 participants (Actual)Interventional2005-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for lactic acid and HIV

ArticleYear
Polylactic acid vs. polyacrylamide hydrogel for treatment of facial lipoatrophy: a randomized controlled trial [Agence Nationale de Recherches sur le SIDA et les Hépatites Virales (ANRS) 132 SMILE].
    HIV medicine, 2013, Volume: 14, Issue:7

    Topics: Acrylic Resins; Adult; Aged; Anti-HIV Agents; Face; Female; HIV; HIV Infections; HIV-Associated Lipo

2013

Other Studies

10 other studies available for lactic acid and HIV

ArticleYear
Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition.
    Mucosal immunology, 2017, Volume: 10, Issue:6

    Topics: Anti-Inflammatory Agents; Cell Line; Cytokines; Epithelial Cells; Female; HIV; HIV Infections; Human

2017
Controlled delivery of heat shock protein using an injectable microsphere/hydrogel combination system for the treatment of myocardial infarction.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Aug-04, Volume: 137, Issue:3

    Topics: Alginates; Apoptosis; Cell Hypoxia; Cell Line; Cell Proliferation; Cell Survival; Delayed-Action Pre

2009
Hyperlactatemia and in utero exposure to antiretrovirals: is the control group the clue?
    AIDS research and human retroviruses, 2012, Volume: 28, Issue:8

    Topics: Acidosis, Lactic; Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Cohort Studi

2012
Single chain variable fragment CD7 antibody conjugated PLGA/HDAC inhibitor immuno-nanoparticles: developing human T cell-specific nano-technology for delivery of therapeutic drugs targeting latent HIV.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Nov-30, Volume: 152 Suppl 1

    Topics: Anti-HIV Agents; Antigens, CD7; Cell Line; Chemistry, Pharmaceutical; Chromatography, High Pressure

2011
Submicron-size biodegradable polymer-based didanosine particles for treating HIV at early stage: an in vitro study.
    Journal of microencapsulation, 2012, Volume: 29, Issue:7

    Topics: Animals; Anti-HIV Agents; Cells, Cultured; Delayed-Action Preparations; Didanosine; Drug Evaluation,

2012
Lactic acidemia in infection with human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Apr-01, Volume: 36, Issue:Suppl 2

    Topics: Acidosis, Lactic; HIV; HIV Infections; Humans; Lactic Acid; Outcome Assessment, Health Care; Reverse

2003
Mucosal immunization with PLGA-microencapsulated DNA primes a SIV-specific CTL response revealed by boosting with cognate recombinant modified vaccinia virus Ankara.
    Virology, 2003, Aug-15, Volume: 313, Issue:1

    Topics: Administration, Rectal; AIDS Vaccines; Animals; Cytotoxicity Tests, Immunologic; Drug Carriers; Drug

2003
Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.
    European journal of endocrinology, 2005, Volume: 152, Issue:1

    Topics: Adult; Alanine; Antiretroviral Therapy, Highly Active; Blood Glucose; Body Composition; Cholesterol,

2005
Use of a biopolymer polyalkylimide filler for facial lipodystrophy in HIV-positive patients undergoing treatment with antiretroviral drugs.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2006, Volume: 32, Issue:6

    Topics: Adult; Aged; Anti-Retroviral Agents; Biopolymers; Cosmetic Techniques; Face; Female; Follow-Up Studi

2006
Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine.
    The Journal of biological chemistry, 1989, Jul-15, Volume: 264, Issue:20

    Topics: Antiviral Agents; Cell Line; Cell Survival; Deoxyribonuclease BamHI; Dideoxynucleosides; DNA, Mitoch

1989