khellin and Keloid
khellin has been researched along with Keloid in 3808 studies
Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.
Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the role of mitomycin C in reducing keloid recurrence." | 10.25 | Role of mitomycin C in reducing keloid recurrence: patient series and literature review. ( Gupta, M; Narang, T, 2011) |
| "This study aimed to investigate the efficacy and therapeutic mechanism of oral tofacitinib in keloid patients." | 9.69 | An Open-Label, Uncontrolled, Single-Arm Clinical Trial of Tofacitinib, an Oral JAK1 and JAK3 Kinase Inhibitor, in Chinese Patients with Keloid. ( Chen, JY; Deng, CC; Feng, QL; He, RL; Pan, HH; Yang, B; Zhu, DH, 2023) |
| "In this clinical trial, we investigated the efficacy of two treatment methods for keloids resulting from surgical incisions: intralesional triamcinolone injections alone versus in combination with verapamil." | 9.69 | Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial. ( Esmailzadeh, M; Hadadi, R; Haghani-Dogahe, Z; Mobayen, M, 2023) |
| "Concerning the treatment of keloids and hypertrophic scars, TAC was more effective than verapamil for improving vascularity; TAC was superior to verapamil in improving height within 9 weeks of treatment; TAC produced superior result for improving pliability within 18 weeks of treatment, whereas verapamil produced superior result between 18 and 24 weeks of treatment." | 9.41 | Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis. ( Li, X; Zhang, W, 2023) |
| "We aimed to determine whether and how Strontium-90 brachytherapy as an adjuvant radiation could affect keloid recurrence after intralesional triamcinolone and 5-fluorouracil injections." | 9.41 | Strontium-90 brachytherapy following intralesional triamcinolone and 5-fluorouracil injections for keloid treatment: A randomized controlled trial. ( Deng, K; Liu, X; Liu, Y; Ogawa, R; Xiao, H; Xu, X, 2021) |
| "We compared the efficacy and side effects of intra-lesional verapamil and triamcinolone in patients with keloids." | 9.41 | A comparison of intralesional verapamil and triamcinolone monotherapy in the treatment of keloids in an African population. ( Belie, MF; Belie, O; Mofikoya, BO; T Omidiji, OA; Ugburo, AO, 2021) |
| "The objective was to establish the safety and efficacy of intralesional 5-fluorouracil (5-FU) for the treatment of keloids and hypertrophic scars." | 9.30 | Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial. ( Ahmad, S; Khalid, FA; Mehrose, MY; Mujahid, AM; Rehman, SU; Saleem, M; Tarar, MN; Yousaf, MA, 2019) |
| "The objective of this study was to compare the efficacy of post-excision intralesional 5-fluorouracil/triamcinolone acetonide (5-FU/TAC) and post-excision radiotherapy in the treatment of ear keloids." | 9.27 | The efficacy of excision followed by intralesional 5-fluorouracil and triamcinolone acetonide versus excision followed by radiotherapy in the treatment of ear keloids: A randomized control trial. ( Amin, M; Farooq, UK; Khalid, FA; Khan, KU; Mehrose, Y; Rabbani, J; Saleem, M; Tarar, MN, 2018) |
| "Our results did not support verapamil's capability in treatment of keloid nor hypertrophic scars." | 9.27 | Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial. ( Abedini, R; Mahmoudi, HR; Nasimi, M; Sasani, P; Shadlou, Z; Teymourpour, A, 2018) |
| "Keloid is conventionally treated with intra-lesional (IL) triamcinolone, which is highly operator dependent and has its own adverse effects." | 9.24 | A Randomized, Single-Blind Trial of Clobetasol Propionate 0.05% Cream Under Silicone Dressing Occlusion Versus Intra-Lesional Triamcinolone for Treatment of Keloid. ( Imran, FH; Ismail, R; Jamil, A; Nor, NM; Shah, SA, 2017) |
| "To study the benefit of applying topical anesthetics or a 1:1 mixture of 1% lidocaine and TA at the TA injection site to alleviate pain during keloid treatment." | 9.24 | A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial. ( Burusapat, C; Usanakornkul, A, 2017) |
| "A double-blind randomized controlled trial with a paired split-scar design compared verapamil, an L-type Ca2+ channel antagonist, and triamcinolone for prevention of keloid recurrence after excision." | 9.22 | Verapamil is Less Effective than Triamcinolone for Prevention of Keloid Scar Recurrence After Excision in a Randomized Controlled Trial. ( Alghamdi, M; Danielsen, PL; Fear, MW; Gankande, TU; Hool, LC; Manzur, M; Rea, SM; Stevenson, AW; Viola, HM; Wallace, HJ; Wood, FM, 2016) |
| "To compare single intra-operative versus an intra-operative and two post-operative injections of triamcinolone after wedge excision of keloids of helix." | 9.20 | Comparison of single intra operative versus an intra operative and two post operative injections of the triamcinolone after wedge excision of keloids of helix. ( Ahmad, H; Bashir, MM; Khan, FA; Yousaf, N, 2015) |
| "to assess the effects of injectable triamcinolone on keloid scars length, height and thickness, and on the number of cells undergoing apoptosis." | 9.20 | Effect of triamcinolone in keloids morphological changes and cell apoptosis. ( de Souza, C; de Vasconcelos, AC; dos Santos, JM; Nunes, TA, 2015) |
| "This prospective study evaluates an argon gas-based system for the treatment of keloids in a patient population including all Fitzpatrick skin types with a 1-year follow-up." | 9.19 | A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy. ( Bulstra, AE; Niessen, FB; van Leeuwen, MC; van Leeuwen, PA, 2014) |
| "To compare the use of intralesional triamcinolone acetonide and its combination with 5 flourouracil in the treatment of keloid and hypertrophic scars in terms of reduction in initial height of the scar." | 9.19 | Intralesional triamcinolone alone and in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Bashir, MM; Khan, FA; Khan, MA, 2014) |
| "To compare 5-fluorouracil (5-FU) tattooing and intralesional steroid for treatment of keloids." | 9.16 | Comparison of the efficacy of intralesional triamcinolone acetonide and 5-fluorouracil tattooing for the treatment of keloids. ( Sadeghinia, A; Sadeghinia, S, 2012) |
| "To determine the effects of topical mitomycin C (MC) on shave-removed wounds and fibroblasts of ear keloids." | 9.15 | Ear keloids as a primary candidate for the application of mitomycin C after shave excision: in vivo and in vitro study. ( Chi, SG; Kim, BS; Kim, DW; Kim, GW; Kim, JY; Kim, MB; Lee, SJ; Lee, WJ; Sohn, MY, 2011) |
| "To determine the tolerability and compare the efficacy of imiquimod 5% and vehicle cream in lowering keloid recurrence after shaving." | 9.14 | Treatment of keloid scars post-shave excision with imiquimod 5% cream: A prospective, double-blind, placebo-controlled pilot study. ( Berman, B; Harrison-Balestra, C; Perez, OA; Ramirez, C; Viera, M; Villa, A; Zell, D, 2009) |
| "To investigate whether intralesional injection of low-dose 5-fluorouracil (5-Fu) and corticosteroid can increase effective rate and decrease recurrence rate of surgically removed auricular keloid." | 9.14 | [Clinical study of auricular keloid treatment with both surgical excision and intralesional injection of low-dose 5-fluorouracil and corticosteroids]. ( Gao, Z; Liu, W; Song, N; Wu, XL, 2009) |
| "To compare intralesional triamcinolone acetonide (TAC) alone or combined with onion extract in keloidal and hypertrophic scars." | 9.13 | An open, randomized, controlled, comparative study of the combined effect of intralesional triamcinolone acetonide and onion extract gel and intralesional triamcinolone acetonide alone in the treatment of hypertrophic scars and keloids. ( Arca, E; Koc, E; Kurumlu, Z; Surucu, B, 2008) |
| "Triamcinolone acetonide intralesional injection (TAIL) has been used for the treatment of keloids, but only with limited success." | 9.13 | Effects of interferon-alpha2b on keloid treatment with triamcinolone acetonide intralesional injection. ( Kim, SE; Lee, AY; Lee, JH, 2008) |
| "The aim of this study was to conduct a meta-analysis of the effectiveness and safety of verapamil and TAC in the treatment of HSs and keloids." | 9.12 | Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials. ( Bi, H; Gu, L; Qin, Z; Wang, P; Wang, Q, 2021) |
| "TAC may be beneficial for the short-term treatment of hypertrophic scars and keloids; however, 5-FU, 5-FU+TAC, and verapamil may produce superior results for medium- and long-term treatments." | 9.12 | The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021) |
| "To explore the effect of intralesional injection of low concentration 5-fluorouracil (5-FU) on inhibition of angiogenesis of keloid." | 9.12 | [Clinical study on keloid treatment with intralesional injection of low concentration 5-fluorouracil]. ( Cao, YL; Liu, W; Wu, XL, 2006) |
| "To investigate whether topical imiquimod 5% cream applied postoperatively after tangential excision can prevent recurrence of earlobe keloids." | 9.12 | Successful treatment of earlobe keloids with imiquimod after tangential shave excision. ( Stashower, ME, 2006) |
| "To evaluate the efficacy of 5% imiquimod cream in the prevention of recurrence of excised keloids." | 9.12 | The efficacy of 5% imiquimod cream in the prevention of recurrence of excised keloids. ( Chuangsuwanich, A; Gunjittisomram, S, 2007) |
| "To evaluate the efficacy and side effects of 5-fluorouracil (5-FU) as a therapeutic agent in the treatment of keloids of any duration or size." | 9.11 | Intralesional 5-fluorouracil as a treatment modality of keloids. ( Nanda, S; Reddy, BS, 2004) |
| "To compare the clinical response of keloidal and hypertrophic scars after treatment with intralesional corticosteroid alone or combined with 5-fluorouracil (5-FU), 5-FU alone, and the 585-nm flashlamp-pumped pulsed-dye laser (PDL)." | 9.10 | Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments. ( Fitzpatrick, RE; Manuskiatti, W, 2002) |
| "This clinical study determines the effectiveness of verapamil hydrochloride on the prevention and treatment of keloids." | 9.10 | Prevention and treatment of keloids with intralesional verapamil. ( Baroni, A; Brongo, S; D'Andrea, F; Ferraro, G, 2002) |
| "The possibility of altering the pathophysiology of keloid scars was investigated in 11 patients, using a single application of 5-fluorouracil solution for 5 minutes after extralesional excision was performed." | 9.09 | The effects of a single dose of 5-fluorouracil on keloid scars: a clinical trial of timed wound irrigation after extralesional excision. ( Chapman, P; Kakar, S; Khan, U; McGrouther, AD; Talas, G; Uppal, RS, 2001) |
| "It appears that TAC is more effective than verapamil for improving scar pliability and vascularity in keloids and hypertrophic scars after 3 weeks of treatment." | 9.05 | The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis. ( Fu, ZH; Guo, GH; Jiang, ZY; Liao, XC; Liu, MZ; Min, DH, 2020) |
| " Predictor variables were 5-fluorouracil (5-FU) or triamcinolone adjuvant therapy, and the outcome variable was keloid recurrence rate." | 8.93 | Could 5-Fluorouracil or Triamcinolone Be an Effective Treatment Option for Keloid After Surgical Excision? A Meta-Analysis. ( Kim, JS; Shin, JY, 2016) |
| " The recurrence rate after surgical excision of an ear keloid in the triamcinolone group was estimated as 15." | 8.93 | A Comparison of the Effectiveness of Triamcinolone and Radiation Therapy for Ear Keloids after Surgical Excision: A Systematic Review and Meta-Analysis. ( Lee, JW; Lee, NH; Roh, SG; Shin, JY; Yang, KM, 2016) |
| "Mitomycin C (MMC) is an antineoplastic antibiotic that has been used off-label in the treatment of hypertrophic scars and keloids." | 8.89 | Mitomycin C in the treatment of keloids: a case and review. ( Chotzen, VA; Kilmer, SL; Kleinerman, R, 2013) |
| "To describe the method for using imiquimod 5% cream in the prevention of keloid recurrence after surgery." | 8.82 | Imiquimod 5% cream for keloid management. ( Berman, B; Villa, A, 2003) |
| "To clarify the dosimetric characteristics of a real-time variable shape rubber-containing tungsten (STR) bolus in a clinical plan and investigate the efficacy of the STR bolus in photon radiotherapy for keloids and other superficial tumors." | 8.31 | Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors. ( Monzen, H; Nakamura, K; Nishimura, Y; Sakai, Y; Tamura, M, 2023) |
| "When comparing with topical lidocaine/prilocaine (EMLA) cream, a 1:1 mixture of 1% lidocaine and epinephrine significantly alleviated pain during and after the corticosteroid injection." | 8.31 | Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study. ( Park, TH, 2023) |
| "We retrospectively analysed the combined application of bleomycin and triamcinolone for the treatment of keloids and hypertrophic scars." | 8.31 | The combined application of bleomycin and triamcinolone for the treatment of keloids and hypertrophic scars: An effective therapy for treating refractory keloids and hypertrophic scars. ( Luo, QF, 2023) |
| "This study aimed to evaluate the efficacy of photodynamic therapy (PDT) with topical indocyanine green (ICG) in the treatment of keloid lesions." | 8.12 | Evaluating the efficacy of photodynamic therapy with indocyanine green in the treatment of keloid. ( Ahmadpour, F; Fakhraei, S; Hoseininezhad, M; Rajabi, O; Sazgarnia, A; Taheri, AR; Zamiri, F, 2022) |
| "The histopathological changes and immunohistochemical studies occurring in keloids in vivo after treatment by intralesional (IL) verapamil are not yet assessed." | 8.02 | Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study. ( Abou-Taleb, DAE; Badary, DM, 2021) |
| "Individualized surgery combined with early postoperative radiotherapy and triamcinolone acetonide injection is an ideal treatment method to ensure good auricular appearance, low incidences of complications and recurrence based on effective treatment of auricular keloids." | 8.02 | Individualized surgery combined with radiotherapy and triamcinolone acetonide injection for the treatment of auricular keloids. ( Guo, S; Sun, Q; Tong, S; Yu, ET; Zhou, KJ; Zhou, Y, 2021) |
| "To assess the effects of curcumol on the proliferation, apoptosis and collagen synthesis of keloid fibroblasts and explore the underlying mechanism." | 8.02 | [Curcumol inhibits keloid fibroblast proliferation and collagen synthesis through the ERK signaling pathway]. ( Sun, H; Wang, J; Yu, L; Yuan, W, 2021) |
| "Intralesional injection of triamcinolone acetonide is an effective method for treating keloids." | 7.96 | Evaluation of the efficacy of triamcinolone acetonide in the treatment of keloids by high-frequency ultrasound. ( Cai, L; Hu, M; Li, Z; Lin, L; Liu, J; Zheng, T, 2020) |
| " However, the effect of PDT mediated by the photosensitizer hematoporphyrin monomethyl ether (HMME) on keloids is not known well." | 7.96 | Hematoporphyrin monomethyl ether-mediated photodynamic therapy inhibits the growth of keloid graft by promoting fibroblast apoptosis and reducing vessel formation. ( Chen, X; Cui, X; Wu, X; Xu, P; Yang, S; Yao, X; Zhu, J; Zhu, W, 2020) |
| "Intralesional 5-fluorouracil (5-FU) in combination with triamcinolone acetonide (TAC) has been recommended as a promising alternative for keloids not responding to silicone-based products, cryotherapy or intralesional corticosteroids alone." | 7.96 | Treatment of keloids using 5-fluorouracil in combination with crystalline triamcinolone acetonide suspension: evaluating therapeutic effects by using non-invasive objective measures. ( Gauglitz, GG; Guertler, A; Poetschke, J; Reinholz, M; Schwaiger, H, 2020) |
| "We aimed to evaluate the clinical outcomes of intralesional excision followed by postoperative triamcinolone acetonide intralesional injection (TA ILI) as auricular keloid treatments." | 7.96 | Auricular keloid management in Asian skin: Clinical outcome of intralesional excision and postoperative triamcinolone acetonide intralesional injection. ( Choi, YJ; Kim, WS; Lee, GY; Lee, HJ; Lee, YH, 2020) |
| "The current experiment was performed to investigate whether luteolin affects the proliferation and apoptosis of keloid fibroblasts by regulating the expression of FRAT1 gene." | 7.96 | Luteolin affects keloid fibroblast proliferation and apoptosis by regulating FRAT1 gene expression. ( Liu, W; Wei, S; Zhang, X, 2020) |
| "Triamcinolone acetonide intralesional injections significantly increased apoptosis in keloids, represented by increased caspase 3 protein and TUNEL expressions, supporting that steroids suppress keloids in part owing to enhancement of apoptosis." | 7.91 | Triamcinolone Acetonide Suppresses Keloid Formation Through Enhancing Apoptosis in a Nude Mouse Model. ( Chen, AD; Chen, RF; Huang, YT; Kuo, YR; Lai, CS; Li, YT; Lin, SD, 2019) |
| "To evaluate the effectiveness of combined ablative fractional CO2 laser and topically applied 5-fluorouracil (5-FU) or verapamil hydrochloride in the treatment of hypertrophic scars (HTSs) and keloids and to examine their possible effects on TGF-β1 expression." | 7.91 | The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study. ( Abd El Azez, TA; Abdel Rahman, SH; Hussein, MS; Sabry, HH; Sanad, RR, 2019) |
| "We conducted this experimental study to analyze the relationship between sphingosine-1-phosphate (S1P)-induced mitogen-activated protein (MAP) kinase pathways and keloid formation." | 7.91 | Association between sphingosine-1-phosphate-induced signal transduction via mitogen-activated protein kinase pathways and keloid formation. ( Chung, H; Jo, DI; Jung, SH; Kim, B; Kim, SH; Ko, HM; Lee, DH; Lee, SH; Song, YK, 2019) |
| "To create three-dimensional poly lactic-co-glycolic acid (PLGA) scaffolds containing autologous platelet-rich plasma (PRP) as an in vitro culture environment for keloid fibroblasts (KL), and to study their implantation into nude mice to mimic the process of keloid formation." | 7.88 | Three-dimensional poly lactic-co-glycolic acid scaffold containing autologous platelet-rich plasma supports keloid fibroblast growth and contributes to keloid formation in a nude mouse model. ( Chen, C; Li, F; Luo, S; Sun, Z; Wang, H; Xu, X; Zhu, G, 2018) |
| "The aim of this study was to evaluate the effect of intralesional tamoxifen on keloids, particularly on the concentration of fibroblasts, dermal inflammatory infiltrate, and collagen degeneration." | 7.85 | Morphological and morphometric analysis of the effects of intralesional tamoxifen on keloids. ( Alencar, AP; da Silva, BB; Filho, LL; Soares-Lopes, IM; Soares-Lopes, LR, 2017) |
| "To explore the effect of simvastatin on the proliferation, apoptosis and protein expressions of keloid fibroblasts under normoxia,hypoxia or TGF-β1 treatment." | 7.83 | [Different effects of simvastatin on keloid fibroblasts under hypoxia and TGF-β1 treatment]. ( An, Y; Chen, B; Kang, C; Qin, Z; Yu, D; Zhao, X, 2016) |
| "The aim of this study was to analyse the effect of captopril on collagen metabolisms in keloid fibroblast cells, and to provide information for the mechanism and therapy of keloid." | 7.83 | Effect of captopril on collagen metabolisms in keloid fibroblast cells. ( Cen, Y; Chen, J; Liu, Y; Nicolas, C; Zhao, S, 2016) |
| "The aim of this study was to investigate the prevalences of hypertrophic scars and keloids in acne patients treated with oral isotretinoin." | 7.83 | Observational retrospective study evaluating the effects of oral isotretinoin in keloids and hypertrophic scars. ( Bagatin, E; Gonçalves, RG; Guadanhim, LR, 2016) |
| "To investigate the effect of Metformin on the proliferation and collagen synthesis of the human keloids fibroblasts as well as the effect on phosphorylation of Akt/FoxO1 signal transduction pathway." | 7.81 | [The effect of Metformin on the proliferation and collagen synthesis of human keloids fibroblasts]. ( Weiyuan, M; Yi, S, 2015) |
| "To determine and compare the effectiveness of silicone gel and tretinoin cream for the prevention of hypertrophic scars and keloids resulting from postoperative wounds and for scar improvement." | 7.80 | Comparative effect of topical silicone gel and topical tretinoin cream for the prevention of hypertrophic scar and keloid formation and the improvement of scars. ( Kwon, SY; Park, K; Park, SD, 2014) |
| "To investigate the treatment of auricular keloid with dinuclear surgery and intralesional injection of compound Betamethasone." | 7.80 | [Treatment of auricular keloids with surgery and intralesional injection of compound betamethasone]. ( Li, W; Liao, H; Liu, W; Wang, F; Yang, H, 2014) |
| "This study designs an alternative transdermal delivery system for 10,11-methylenedioxycamptothecin(MD-CPT) to inhibit keloid." | 7.80 | Transdermal delivery of 10,11-methylenedioxycamptothecin by hyaluronic acid based nanoemulsion for inhibition of keloid fibroblast. ( Chen, X; Cheng, X; Gao, T; Gao, Y; Kong, M; Li, P; Wang, J; Wang, Z, 2014) |
| "Preliminary clinical trials suggest a superior effect when steroids and 5-fluorouracil are injected together for the intralesional therapy of keloids." | 7.79 | A study of the combination of triamcinolone and 5-fluorouracil in modulating keloid fibroblasts in vitro. ( Burd, A; Cai, YJ; Huang, L; Leung, BC; Lung, I, 2013) |
| "The effects of locally produced chitosan (CPSRT-NC-bicarbonate) in the intervention of keloid pathogenesis were investigated in vitro." | 7.79 | Keloid pathogenesis via Drosophila similar to mothers against decapentaplegic (SMAD) signaling in a primary epithelial-mesenchymal in vitro model treated with biomedical-grade chitosan porous skin regenerating template. ( Halim, AS; Lim, CK; Noorsal, K; Yaacob, NS; Zainol, I, 2013) |
| "To investigate the efficacy of topical and intralesional mitomycin C for the treatment of keloids and HTS." | 7.78 | Treatment of keloids and hypertrophic scars using topical and intralesional mitomycin C. ( Seo, SH; Sung, HW, 2012) |
| "Methanolic extraction of honey has positive anti proliferative effect on keloid fibroblasts in a dose-dependent manner." | 7.77 | Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts. ( Gan, SH; Halim, AS; Nurul Syazana, MS; Shamsuddin, S, 2011) |
| " Five and 2 months before presentation, she was treated with intradermal triamcinolone acetonide for keloid scars." | 7.76 | Cushing's syndrome and adrenal insufficiency after intradermal triamcinolone acetonide for keloid scars. ( Finken, MJ; Mul, D, 2010) |
| "Intralesional injection of low-dose 5-fluorouracil (5-FU) has recently been used as an experimental modality for treating keloid scarring and has shown promising efficacy in improving scar appearance and preventing recurrence of the keloid." | 7.76 | Low-dose 5-fluorouracil induces cell cycle G2 arrest and apoptosis in keloid fibroblasts. ( Burd, A; Cai, YJ; Huang, L; Leung, CS; Lung, I; Wong, YP, 2010) |
| "To investigate the effect of the PPAR-gamma agonist troglitazone on transforming growth factor (TGF)-beta1-induced collagen type I expression in keloid fibroblasts." | 7.75 | Troglitazone suppresses transforming growth factor-beta1-induced collagen type I expression in keloid fibroblasts. ( Chen, XL; Gao, WY; Guo, SZ; Li, X; Li, ZJ; Ma, B; Yi, CG; Zhang, GY, 2009) |
| "Pretreatment with 60% lidocaine tape significantly reduces the pain associated with intralesional injection of TA." | 7.75 | Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid. ( Hyakusoku, H; Murakami, M; Tosa, M, 2009) |
| "To evaluate the efficacy of topical imiquimod 5% cream applied after surgical excision and primary closure of trunk keloids in the prevention of recurrence." | 7.75 | Failure of imiquimod 5% cream to prevent recurrence of surgically excised trunk keloids. ( Cação, FM; Messina, MC; Tanaka, V, 2009) |
| "To study the expression and function of sphingosine kinase (SphK) 1 and SphK2 in human keloid fibroblasts." | 7.75 | [Expression and function of sphingosine kinases 1 and 2 in human keloid fibroblasts]. ( Cai, JL; Liu, ZZ; Wang, LX; Wang, W; Xu, B; Zhang, J; Zhang, JX, 2009) |
| "The purpose of this study was to report severe keloids caused by hydrogen cyanide injury." | 7.74 | Severe keloids caused by hydrogen cyanide injury: a case report. ( Guo, G; Jian, X; Lin, D; Ruan, Y; Zhao, B, 2008) |
| "To determine whether application of mitomycin C to the base of shave-removed keloids would prevent their recurrence." | 7.74 | Application of topical mitomycin C to the base of shave-removed keloid scars to prevent their recurrence. ( Bailey, JN; Clayton, WJ; Rustin, MH; Waite, AE, 2007) |
| "To examine the effect of aspirin on the tumor necrosis factor (TNF)-alpha-induced NF-kappaB activation in keloid fibroblasts." | 7.74 | Abnormal nuclear factor (NF)-kappaB signal pathway and aspirin inhibits tumor necrosis factor alpha-induced NF-kappaB activation in keloid fibroblasts. ( Cai, J; Xu, B; Zhang, J; Zhao, Y; Zhu, G, 2007) |
| "Imiquimod 5% cream has been found to be effective and safe in preventing recurrence of keloids on earlobes after excision." | 7.74 | Imiquimod 5% cream for the prevention of recurrence after excision of presternal keloids. ( Gupta, S; Khaitan, BK; Malhotra, AK; Sharma, VK, 2007) |
| "To investigate the relations between thymosin beta 4 and pathologic scars by comparing the mRNA levels of thymosin beta 4 in keloid, hypertrophic scar and normal skin." | 7.73 | [Expression of thymosin beta 4 mRNA expression in keloid tissues and fibroblasts cultured from keloid and its significance]. ( Nie, FF; Qin, ZL; Wu, JQ, 2005) |
| "To establish the safety and efficacy of imiquimod 5% cream in the prevention of recurrences of excised earlobe keloids." | 7.73 | Postsurgical use of imiquimod 5% cream in the prevention of earlobe keloid recurrences: results of an open-label, pilot study. ( Busquets, AC; Martin-García, RF, 2005) |
| "We studied the long-term outcome of injection of triamcinolone acetonide into keloid scars in Asian patients." | 7.73 | Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients. ( Hata, Y; Igawa, HH; Ito, O; Muneuchi, G; Onodera, M; Suzuki, S, 2006) |
| "Isotretinoin-induced keloid formation has occasionally been reported in patients who have undergone dermabrasion or laser treatment." | 7.73 | Possible isotretinoin-induced keloids in a patient with Behçet's disease. ( Dogan, G, 2006) |
| "To investigate the effects of quercetin and X-ray on collagen synthesis of cultured human keloid-derived fibroblast and the mechanism." | 7.73 | Influence of quercetin and x-ray on collagen synthesis of cultured human keloid-derived fibroblasts. ( Long, X; Wang, XJ; Zeng, X; Zhang, FQ, 2006) |
| "We have assessed the in vitro effects of quercetin on proliferation, collagen synthesis and the expression of the IGF system in keloid-derived fibroblasts." | 7.72 | Suppression of insulin-like growth factor signalling pathway and collagen expression in keloid-derived fibroblasts by quercetin: its therapeutic potential use in the treatment and/or prevention of keloids. ( Chan, SY; Huynh, H; Lee, ST; Nguyen, TT; Phan, TT; See, P; Tran, E, 2003) |
| "We performed a retrospective chart review of 3 pediatric patients who developed Cushing's syndrome after local administration of triamcinolone acetonide (TCA)." | 7.72 | Cushing's syndrome after intra-articular and intradermal administration of triamcinolone acetonide in three pediatric patients. ( Kumar, S; Lteif, AN; Reed, AM; Singh, RJ, 2004) |
| "Quercetin significantly inhibited the expression of TGF-beta receptors 1 and 2 in keloid fibroblasts at three concentrations (low, medium, and high)." | 7.72 | Suppression of transforming growth factor beta/smad signaling in keloid-derived fibroblasts by quercetin: implications for the treatment of excessive scars. ( Chan, SY; Lee, ST; Lim, IJ; Longaker, MT; Phan, TT; Tan, EK, 2004) |
| "In this study, different molecular weight CM-chitosans were prepared and the effects on the growth and collagen secretion of normal skin fibroblasts and keloid fibroblasts were investigated in vitro." | 7.71 | The effect of carboxymethyl-chitosan on proliferation and collagen secretion of normal and keloid skin fibroblasts. ( Chen, XG; Liu, WS; Park, HJ; Wang, Z, 2002) |
| " In the present study the effects of biomedically relevant hexose sugars (glucose, fructose, galactose, mannose) and sucrose disaccharide on the expression of COX-1 and COX-2 genes were evaluated in granulation tissue fibroblasts, hypertrophic scar fibroblasts and keloid fibroblasts." | 7.71 | Differential effects of hexoses and sucrose, and platelet-derived growth factor isoforms on cyclooxygenase-1 and -2 mRNA expression in keloid, hypertrophic scar and granulation tissue fibroblasts. ( Kössi, J; Laato, M; Peltonen, J; Uotila, P, 2001) |
| "The experimental drug pirfenidone (PFD) has been evaluated as an inhibitor of keloid proliferation and compared with triamcinolone (TAC) injections by studying the involution of active human keloid implants in athymic nude mice (nu-nu)." | 7.70 | Involution of keloid implants in athymic mice treated with pirfenidone or with triamcinolone. ( Bloom, RF; Margolin, SB; Shetlar, CL; Shetlar, DJ; Shetlar, MR, 1998) |
| "We have previously reported that tranilast, an anti-allergic agent, specifically suppresses collagen synthesis in normal skin fibroblasts and to a greater extent in keloid fibroblasts." | 7.69 | Tranilast inhibits collagen synthesis in normal, scleroderma and keloid fibroblasts at a late passage culture but not at an early passage culture. ( Nishikawa, T; Tajima, S; Yamada, H, 1995) |
| "The mechanical properties of 17 keloids in 9 patients before and during treatment with intralesional triamcinolone acetonide were studied using a recently developed noninvasive suction device for measuring skin elasticity in vivo." | 7.69 | Mechanical properties of keloids in vivo during treatment with intralesional triamcinolone acetonide. ( Krusche, T; Worret, WI, 1995) |
| "In this study, we evaluated the effects of isotretinoin and triamcinolone acetonide on the growth of keloid and embryonal human skin fibroblasts in vitro." | 7.69 | Inhibition of human keloid fibroblast growth by isotretinoin and triamcinolone acetonide in vitro. ( Cruz, NI; Korchin, L, 1994) |
| "Six fibroblast cell strains, derived from keloid or normal skin, exhibited similar growth responses to platelet-derived growth factor, transforming growth factor beta 1 (TGF-beta 1), gamma-interferon (gamma-IFN) and histamine." | 7.69 | Effects of various growth factors and histamine on cultured keloid fibroblasts. ( Kadono, T; Kikuchi, K; Takehara, K, 1995) |
| "Using a 3-dimensional fibrin gel model system simulating fibroplasia of wound repair, we investigated the interaction between keloid fibroblasts and fibrin matrix and compared it with that of normal fibroblasts." | 7.69 | Elevated levels of plasminogen activator inhibitor-1 may account for the altered fibrinolysis by keloid fibroblasts. ( Laug, WE; Nichter, LS; Nimni, ME; Sun, B; Tuan, TL; Zhu, JY, 1996) |
| "The feasibility of iontophoretic transdermal delivery of tranilast (N-(3,4-dimethoxycinnamoyl) anthranilic acid) for the treatment of keloid and hypertrophic scars was evaluated in hairless rats and humans." | 7.69 | Treatment of keloid and hypertrophic scars by iontophoretic transdermal delivery of tranilast. ( Ikuta, Y; Murakami, T; Shigeki, S; Yata, N, 1997) |
| "We studied the inhibitory effects of tranilast, an anti-allergic drug, on the human keloid tissues implanted into the dorsal skin of athymic nude mice and on the growth of keloid fibroblast in vitro." | 7.68 | [Effect of tranilast, an anti-allergic drug, on the human keloid tissues]. ( Arai, N; Hamano, S; Ichikawa, K; Kikuchi, S; Momose, Y; Shibata, N; Sugimoto, C; Suzawa, H; Tazawa, S; Tsuchiya, O, 1992) |
| "Small proteoglycans (PGs), extracted from human keloid scar tissue with 4M guanidinium chloride and fractionated by DEAE-cellulose chromatography, were separated by ethanol precipitation into one L-iduronic acid-rich and one D-glucuronic acid-rich fraction." | 7.68 | Purification and characterization of iduronic acid-rich and glucuronic acid-rich proteoglycans implicated in human post-burn keloid scar. ( Burd, DA; Garg, HG; Lippay, EW; Neame, PJ, 1990) |
| "A potential therapeutic role of minoxidil in fibrotic or sclerotic conditions, such as keloids, has been suggested on the basis of its reported ability to inhibit the proliferation of human dermal fibroblasts." | 7.68 | [Effect of minoxidil on DNA synthesis in cultured fibroblasts from healthy skin or keloids]. ( De Moragas, JM; Martí, F; Piñol, G; Puig, L; Rueda, F, 1990) |
| "Argon and CO2 lasers have been used to treat 13 patients with well-established keloid scars of the trunk or earlobe." | 7.67 | Preliminary results of argon and carbon dioxide laser treatment of keloid scars. ( Apfelberg, DB; Lash, H; Maser, MR; Weston, J; White, D, 1984) |
| "Keloid fibroblasts were propagated in culture and their proliferative behaviour and response to the Epidermal Growth Factor (EGF) were studied." | 7.67 | Keloid fibroblasts in culture: abnormal growth behaviour and altered response to the epidermal growth factor. ( Harper, RA, 1989) |
| "We report the observation of delayed wound healing and keloid formation in three patients, following dermabrasion or Argon laser treatment administered while they were receiving isotretinoin for acne or rosacea." | 7.67 | Delayed wound healing and keloid formation following argon laser treatment or dermabrasion during isotretinoin treatment. ( Zachariae, H, 1988) |
| "The effects of ascorbic acid and hydrocortisone on activity of prolyl hydroxylase in fibroblasts from keloid and normal human dermis were investigated and compared to the effects of these agents on collagen synthesis." | 7.66 | Variation in prolyl hydroxylase activity of keloid-derived and normal human fibroblasts in response to hydrocortisone and ascorbic acid. ( Russell, JD; Russell, SB; Trupin, JS, 1983) |
| "A case of long-term Cushing's syndrome after intradermal injection of 160 mg of triamcinolone diacetate has been presented." | 7.65 | Cushing's syndrome associated with the intradermal injection of triamcinolone diacetate. ( Kolodny, SC; Langston, JR, 1976) |
| " Increasing the dosage and duration of keloid scar treatment is required in future studies to determine whether it would result in a significant therapeutic outcome." | 7.30 | Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study. ( Disphanurat, W; Leelawattanachai, J; Sivapornpan, N; Srisantithum, B, 2023) |
| "Keloids are benign fibro-proliferative growths occurring after skin injury or spontaneously." | 7.11 | Combined intralesional triamcinolone acetonide and platelet rich plasma versus intralesional triamcinolone acetonide alone in treatment of keloids. ( Hegab, DS; Hewedy, ES; Mohamed, WS; Sabaa, BEI, 2022) |
| " This review assesses recurrence and the reporting of recurrence in pathologic scar after treatment with intralesional triamcinolone (TAC) in combination with another intralesional agent." | 7.01 | Recurrence rates in the treatment of keloids and hypertrophic scars with intralesional triamcinolone combined with other intralesional agents. ( Chandy, RJ; Feldman, SR; Khan, D; Rimmer, SN, 2023) |
| "Keloids are a type of disordered scar formation which not only show heterogeneity between individuals and within the scar itself, but also share common features of hyperproliferation, abnormal extra-cellular matrix deposition and degradation, as well as altered expression of the molecular markers of wound healing." | 7.01 | Differential responses to folic acid in an established keloid fibroblast cell line are mediated by JAK1/2 and STAT3. ( Alishahedani, ME; Freeman, AF; McCann, KJ; Myles, IA; Yadav, M, 2021) |
| "Keloids are a major complication related to surgical wound healing and very challenging condition to treat." | 6.94 | Histopathology and immunohistochemical analysis of 5-fluorouracil and triamcinolone treated keloids in double-blinded randomized controlled trial. ( Hietanen, KE; Huhtala, H; Järvinen, TAH; Kaartinen, IS; Tolonen, TT, 2020) |
| "Keloids have high recurrence rates." | 6.90 | Treatment of keloid scars with intralesional triamcinolone and 5-fluorouracil injections - a randomized controlled trial. ( Hietanen, KE; Huhtala, H; Järvinen, TA; Kaartinen, IS; Kuokkanen, HO; Tolonen, TT, 2019) |
| "One of the first-line options to treat keloid scars is corticosteroid injection after excision of the existing scar." | 6.90 | Efficacy of surgical excision and sub-dermal injection of triamcinolone acetonide for treatment of keloid scars after caesarean section: a single blind randomised controlled trial protocol. ( Chua, SC; Gidaszewski, B; Khajehei, M, 2019) |
| "Keloid is characterized by benign overgrowth of dermal collagen in response to skin injury in genetically predisposed individuals." | 6.90 | Comparison of the efficacy of intralesional bleomycin versus intralesional triamcinolone acetonide in the treatment of keloids. ( Khan, HA; Paracha, MM; Sahibzada, MN, 2019) |
| "Keloid and hypertrophic scars are the most common types of pathological scars." | 6.82 | Efficacy of the Neodymium-Doped Yttrium Aluminum Garnet Laser in the Treatment of Keloid and Hypertrophic Scars: A Systematic Review and Meta-analysis. ( Li, C; Pan, L; Qin, H; Yang, L; Zhang, G; Zhang, L, 2022) |
| "Keloids are aesthetically disfiguring and severely disabling." | 6.76 | Effects of combined intralesional 5-Fluorouracil and topical silicone in prevention of keloids: a double blind randomized clinical trial study. ( Ghafarian Shirazi, HR; Hatamipour, E; Hatamipour, M; Mehrabi, S, 2011) |
| "Keloids and hypertrophic scars are benign growths of dermal collagen that can cause physical and psychological (cosmetic) problems for patients." | 6.74 | Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2009) |
| "Keloids are distinguished by substantial deposition of collagen in the dermis, resulting in an imbalanced production and aggregation of extra cellular matrix." | 6.74 | Effect of camptothecin on collagen synthesis in fibroblasts from patients with keloid. ( Gao, WY; Guo, SZ; Han, Y; Li, X; Li, Y; Lu, KH; Ma, XJ; Xiao, B; Yan, L; Yi, CG; Zhang, GY; Zheng, Y, 2009) |
| "Keloids are well-defined fibrous tissue overgrowths extending beyond the original defects." | 6.73 | Role of liquid nitrogen alone compared with combination of liquid nitrogen and intralesional triamcinolone acetonide in treatment of small keloids. ( Bhanot, A; Dewan, SP; Kaur, A; Sharma, S, 2007) |
| "Keloids and hypertrophic scars are harmful to physical and psychological health." | 6.72 | Comparative efficacy and safety of verapamil and triamcinolone in keloid and hypertrophic scar treatment: a meta-analysis. ( An, P; Kuang, J; Li, W, 2021) |
| "Keloids and hypertrophic scars are benign growths of dermal collagen that usually cause major physical, psychological, and cosmetic problems." | 6.72 | New combination of triamcinolone, 5-Fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2006) |
| " Cryosurgery and intralesional corticosteroids have been considered as the mainstream of therapy; however, the long-term use of corticosteroids has been found to be associated with serious side effects." | 6.70 | Efficacy and safety of intralesional 5-fluorouracil in the treatment of keloids. ( Gupta, S; Kalra, A, 2002) |
| "Meta-analysis revealed a recurrence rate of 39% (95% CI = 8." | 6.66 | Imiquimod to prevent keloid recurrence postexcision: A systematic review and meta-analysis. ( Aromataris, EC; Greenwood, JE; Klotz, T; Munn, Z, 2020) |
| " Although triamcinolone acetonide (TAC) is one of the most common and effective treatments for keloids and hypertrophic scars, TAC is not effective in some patients, and some may even experience adverse outcomes." | 6.66 | Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Deng, Z; Liu, L; Liu, R; Yang, B; Zhao, X, 2020) |
| " We aimed to compare the efficacy and safety of TAC alone and in combination with 5-FU for the treatment of hypertrophic scars and keloids." | 6.55 | Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis. ( Fan, B; Feng, S; Lin, W; Ren, Y; Wei, Z; Zhou, X, 2017) |
| "Keloids are benign fibroproliferative diseases of unknown aetiology." | 6.44 | Transforming growth factor beta (TGFbeta) and keloid disease. ( Bayat, A; Jagadeesan, J, 2007) |
| "To study the role of mitomycin C in reducing keloid recurrence." | 6.25 | Role of mitomycin C in reducing keloid recurrence: patient series and literature review. ( Gupta, M; Narang, T, 2011) |
| "In addition, dasatinib-treated keloid fibroblasts conditioned medium reduced procollagen and p16 expression in cultured keloid fibroblasts." | 5.91 | Dasatinib Attenuates Fibrosis in Keloids by Decreasing Senescent Cell Burden. ( Chung, JH; Darmawan, CC; Hur, K; Kusumaningrum, N; Lee, SH; Mun, JH, 2023) |
| " Intra-lesional injection of triamcinolone acetonide (TAC) in combination with 5-fluorouracil (5-FU) is a commonly used pharmacological regimen and long-term repeated injections can achieve sustained inhibition of keloid proliferation." | 5.91 | Deciphering the single-cell transcriptome network in keloids with intra-lesional injection of triamcinolone acetonide combined with 5-fluorouracil. ( Hao, Y; Kuang, X; Liang, Z; Liu, H; Shan, M; Wang, Y; Xia, Y, 2023) |
| "Enalapril and TAA were injected intralesionally in one session per month for three sessions." | 5.91 | Safety and efficacy of intralesional injection of enalapril versus triamcinolone acetonide in the treatment of keloids. ( Eltahlawy, S; Hamada Mohamed, B; Marzouk, WA; Mohamad, NE, 2023) |
| "Psoriasis is a papulosquamous disorder that causes significant social and psychological trauma to the patient." | 5.72 | Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis. ( Attwa, E; Essam, R; Khater, MH; Selim, HM, 2022) |
| "This study aimed to investigate the efficacy and therapeutic mechanism of oral tofacitinib in keloid patients." | 5.69 | An Open-Label, Uncontrolled, Single-Arm Clinical Trial of Tofacitinib, an Oral JAK1 and JAK3 Kinase Inhibitor, in Chinese Patients with Keloid. ( Chen, JY; Deng, CC; Feng, QL; He, RL; Pan, HH; Yang, B; Zhu, DH, 2023) |
| "In this clinical trial, we investigated the efficacy of two treatment methods for keloids resulting from surgical incisions: intralesional triamcinolone injections alone versus in combination with verapamil." | 5.69 | Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial. ( Esmailzadeh, M; Hadadi, R; Haghani-Dogahe, Z; Mobayen, M, 2023) |
| "We used microneedles to treat keloid because this method has the feasibility of self-administration without pain." | 5.62 | Topical delivery of 5-fluorouracil-loaded carboxymethyl chitosan nanoparticles using microneedles for keloid treatment. ( Kim, YC; Park, J, 2021) |
| "The successful treatment of keloids is a great challenge in the plastic surgery field." | 5.62 | Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway. ( Chen, ZY; Liu, XM; Wang, XM; Wang, Y, 2021) |
| "Keloids are characterized by increased deposition of fibrous tissue in the skin and subcutaneous tissue following an abnormal wound healing process." | 5.62 | Halofuginone regulates keloid fibroblast fibrotic response to TGF-β induction. ( Chatelain, B; Dirand, Z; Humbert, P; Isidoro, C; Lihoreau, T; Marty, P; Rolin, G; Secomandi, E; Senez, C; Tissot, M, 2021) |
| " Our results showed that HA combined with red light irradiation treatment (HA-R-PDT) decreased KF viability, reduced KF collagen production and ECM accumulation, inhibited cell proliferation, suppressed cell invasion and induced cell apoptosis." | 5.62 | Antifibrotic effects of Hypocrellin A combined with LED red light irradiation on keloid fibroblasts by counteracting the TGF-β/Smad/autophagy/apoptosis signalling pathway. ( Guo, G; Niu, T; Shi, Y; Tian, Y; Tong, Y; Wang, G, 2021) |
| "Keloid and hypertrophic scars are skin fibrosis-associated disorders that exhibit an uncontrollable proliferation of fibroblasts and their subsequent contribution to the excessive accumulation of extracellular matrix (ECM) in the dermis." | 5.62 | Ameliorating Fibrotic Phenotypes of Keloid Dermal Fibroblasts through an Epidermal Growth Factor-Mediated Extracellular Matrix Remodeling. ( Anggradita, LD; Bae, J; Hur, SS; Hwang, NS; Hwang, Y; Kim, H; Lee, SJ; Nam, SM, 2021) |
| "Keloid is a unique refractory syndrome characterized by a proliferation disorder of the fibroblasts." | 5.62 | Phenalen-1-one-mediated photodynamic therapy inhibits keloid graft progression by reducing vessel formation and promoting fibroblast apoptosis. ( Li, H; Li, Y; Liu, Z; Nie, Y; Shi, L; Wang, H; Wu, H; Zheng, W, 2021) |
| "Keloids are common fibroproliferative tumors, and their treatment still represents a dilemma." | 5.62 | Intralesional pentoxifylline, triamcinolone acetonide, and their combination for treatment of keloid scars. ( Gamea, MM; Hegab, DS; Mahmoud, WH; Serag-Eldin, YMA, 2021) |
| "A keloid is characterized by red, tickling, hard, and irregular raised tissues, and it tends to outgrow its origin." | 5.56 | Resveratrol inhibits proliferation and promotes apoptosis of keloid fibroblasts by targeting HIF-1α. ( Guan, E; Han, Q; Huang, J; Liu, Y; Liu, Z; Long, F; Long, X; Si, L; Wang, X; Zhang, H; Zhang, M; Zhao, R; Zhao, RC, 2020) |
| "Management of keloid is difficult, so there is always a need for adequate and effective therapy." | 5.56 | Comparative evaluation of therapeutic efficacy and safety of intralesional triamcinolone acetonide injection vs intralesional radiofrequency with intralesional triamcinolone acetonide in treatment of keloids. ( Brar, BK; Kaushal, V; Kumar, S; Singh, A, 2020) |
| "Keloids are benign fibroproliferative skin tumors that can cause disfigurement and disability." | 5.51 | Analysis of Keloid Response to 5-Fluorouracil Treatment and Long-Term Prevention of Keloid Recurrence. ( Chong, T; Costa, C; Karimpour-Fard, A; LaRanger, R; Mathes, D; Wright, WE, 2019) |
| "Paclitaxel (PTX) was an effective chemotherapeutic agent and has been reported to have anti-fibrotic effects, but the strong hydrophobicity brings a challenge for its clinical application." | 5.51 | Improving the anti-keloid outcomes through liposomes loading paclitaxel-cholesterol complexes. ( Chen, L; Gao, Z; Huang, W; Jin, M; Jin, Z; Wang, M; Wang, Q, 2019) |
| "Keloids are benign fibrous overgrowths that occur as a result of abnormal wound healing following cutaneous injury." | 5.51 | Trichostatin A‑induced miR‑30a‑5p regulates apoptosis and proliferation of keloid fibroblasts via targeting BCL2. ( Chen, H; Chen, S; Gao, X; He, C; Jian, X; Qu, L; Wang, Y; Zhao, Q; Zou, Q, 2019) |
| "Ginsenoside Rg3 (Rg3) has been reported to exert numerous antitumor effects, thus indicating that Rg3 may be a potential therapeutic agent that targets keloids." | 5.48 | Ginsenoside Rg3 inhibits keloid fibroblast proliferation, angiogenesis and collagen synthesis in vitro via the TGF‑β/Smad and ERK signaling pathways. ( Bian, W; Cheng, L; Jin, R; Tang, M; Wang, W; Zhang, L; Zhang, Y, 2018) |
| "Keloids are a fibroproliferative disorder of the skin resulted from abnormal healing of injured or irritated skin and are characterized by the ability to spread beyond the original boundary of the wound." | 5.48 | Gallic acid inhibits fibroblast growth and migration in keloids through the AKT/ERK signaling pathway. ( Gao, Z; Liu, K; Ruan, M; Wang, X; Yang, J, 2018) |
| "Hypocrellin B (HB) is a natural perylene quinone photosensitizer." | 5.46 | Effects of Photodynamic Therapy Using Yellow LED-light with Concomitant Hypocrellin B on Apoptotic Signaling in Keloid Fibroblasts. ( Han, G; Hu, Y; Jiao, Y; Li, S; Qi, T; Wei, G; Zhang, C, 2017) |
| "Keloids are fibrous growths that occur as a result of abnormal response to dermal injury." | 5.46 | Successful Treatment of Keloid With Fractionated Carbon Dioxide (CO2) Laser and Laser-Assisted Drug Delivery of Triamcinolone Acetonide Ointment in an African-American Man. ( Ho, D; Jagdeo, J; Kraeva, E, 2017) |
| "Keloids are fibroproliferative diseases characterized by the accumulation of an extracellular matrix including collagen." | 5.46 | Sulforaphane suppresses cell growth and collagen expression of keloid fibroblasts. ( Horinaka, M; Kawarazaki, A; Nishino, K; Numajiri, T; Sakai, T; Yasuda, S, 2017) |
| "Verapamil has shown a great potential in the management of keloid and hypertrophic scars." | 5.43 | Role of verapamil in preventing and treating hypertrophic scars and keloids. ( Cen, Y; Chen, J; Li, Z; Mao, Y; Wang, R; Zhang, Z, 2016) |
| "Keloids are considered benign dermal fibroproliferative tumors." | 5.43 | Tanshinone IIA Inhibits Proliferation and Induces Apoptosis Through the Downregulation of Survivin in Keloid Fibroblasts. ( Chen, G; Li, Q; Liang, X; Liang, Y; Liu, D, 2016) |
| "Keloids are progressively expanding scars, mostly prevalent in individuals of African descent." | 5.43 | The role of aldo-keto reductase 1C3 (AKR1C3)-mediated prostaglandin D2 (PGD2) metabolism in keloids. ( Frazier, R; Katdare, M; Mantel, A; Newsome, A; Thekkudan, T, 2016) |
| "Keloids are wounding-induced tumor-like human scars." | 5.43 | Keloid-derived, plasma/fibrin-based skin equivalents generate de novo dermal and epidermal pathology of keloid fibrosis in a mouse model. ( Benya, PD; Chiu, WC; Choi, A; Hsu, T; Kim, EW; Kulber, DA; Lee, YS; Sarkozy, H; Tuan, TL, 2016) |
| "Scar pruritus is frequently encountered in clinical practice (particularly in burn patients) owing to its poorly known pathogenesis and difficult treatment." | 5.43 | Solanidine and tomatidine trigger scar pruritus. ( Alonso, PE; Rioja, LF, 2016) |
| "Sorafenib is a promising agent for the treatment of keloids and hypertrophic scars." | 5.43 | Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways. ( Chen, YL; Ding, X; Gao, Z; Gu, T; Liu, W; Qu, M; Wang, W; Wu, X; Xu, L; Zhang, W, 2016) |
| "The literature on keloids is replete with authors expressing frustration with treatment results." | 5.43 | Strategy for Successful Management of Facial Keloid Using Triamcinolone Injection as Adjunct to Surgery. ( Aluko-Olokun, B; Olaitan, AA, 2016) |
| "Concerning the treatment of keloids and hypertrophic scars, TAC was more effective than verapamil for improving vascularity; TAC was superior to verapamil in improving height within 9 weeks of treatment; TAC produced superior result for improving pliability within 18 weeks of treatment, whereas verapamil produced superior result between 18 and 24 weeks of treatment." | 5.41 | Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis. ( Li, X; Zhang, W, 2023) |
| "We aimed to determine whether and how Strontium-90 brachytherapy as an adjuvant radiation could affect keloid recurrence after intralesional triamcinolone and 5-fluorouracil injections." | 5.41 | Strontium-90 brachytherapy following intralesional triamcinolone and 5-fluorouracil injections for keloid treatment: A randomized controlled trial. ( Deng, K; Liu, X; Liu, Y; Ogawa, R; Xiao, H; Xu, X, 2021) |
| "We compared the efficacy and side effects of intra-lesional verapamil and triamcinolone in patients with keloids." | 5.41 | A comparison of intralesional verapamil and triamcinolone monotherapy in the treatment of keloids in an African population. ( Belie, MF; Belie, O; Mofikoya, BO; T Omidiji, OA; Ugburo, AO, 2021) |
| "Keloids and hypertrophic scars are common lesions, which typically present as a cosmetic concern; however, they also can cause significant pruritus and pain." | 5.39 | Combination treatment of CO2 fractional laser, pulsed dye laser, and triamcinolone acetonide injection for refractory keloid scars on the upper back. ( Collawn, SS; Martin, MS, 2013) |
| "Keloids are characterized by the vigorously continuous production of extracellular matrix protein and aberrant cytokine activity in the dermis." | 5.39 | Thalidomide inhibits fibronectin production in TGF-β1-treated normal and keloid fibroblasts via inhibition of the p38/Smad3 pathway. ( Chen, YL; Chien, HF; Hung, LY; Lee, CW; Liang, CJ; Pu, CM; Tsai, JS; Wang, SH; Yen, FL; Yen, YH, 2013) |
| "Keloids are fibroproliferative disorders characterized by exuberant extracellular matrix deposition and transforming growth factor (TGF)-β/Smad pathway plays a pivotal role in keloid pathogenesis." | 5.39 | Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation. ( Bian, D; Dai, Y; Dou, Y; Gong, Z; Tan, Q; Wu, X; Xia, Y; Yang, Y; Zhang, J, 2013) |
| "Pirfenidone is a novel anti-fibrotic agent that inhibits the progression of fibrosis occurring in the keloid lesions of the lung and kidney." | 5.38 | Pirfenidone suppresses keloid fibroblast-embedded collagen gel contraction. ( Maeda, T; Matsumura, H; Saito, M; Setoguchi, Y; Tsuboi, R; Yamazaki, M, 2012) |
| "Keloid is a specific skin scar that expands beyond the boundaries of the original injury as it heals." | 5.38 | Madecassoside suppresses migration of fibroblasts from keloids: involvement of p38 kinase and PI3K signaling pathways. ( Bian, D; Dai, Y; Gong, Z; Lu, Q; Song, J; Wei, Z; Xia, Y; Xu, H; Xu, Z, 2012) |
| "Keloids are benign dermal tumors characterized by fibroblastic proliferation and excessive accumulation of collagen." | 5.38 | Oxymatrine inhibits collagen synthesis in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway. ( Fan, DL; Guo, S; Han, SY; Wang, YX; Zhao, WJ, 2012) |
| "Tacrolimus is an immunomodulator that could be useful in treating keloid." | 5.37 | Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis. ( Blondel, WC; Chassagne, JF; Gisquet, H; Guillemin, F; Latarche, C; Leroux, A; Liu, H; Merlin, JL; Peiffert, D, 2011) |
| "Keloids are recognized as benign tumours characterized by fibroblastic proliferation and accumulation of extracellular matrix, especially collagen deposition." | 5.36 | Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts. ( He, S; Huang, W; Liu, X; Roberts, MS; Xu, S; Yang, S; Yang, Y; Zhang, X, 2010) |
| "Curcuminoids have been found to inhibit fibrosis." | 5.36 | Suppression of TGF-β1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid. ( Chang, CC; Chen, MJ; Hsu, YC; Ko, SY; Yu, YM, 2010) |
| "Keloids are raised reddish nodules that develop at the site of an injury." | 5.35 | A custom-made silicon mold for pressure therapy to ear keloids. ( Alyanak, A; Guven, E; Yazar, M; Yigit, B, 2009) |
| "Keloids are benign skin tumors characterized by collagen accumulation and hyperproliferation of fibroblasts." | 5.35 | Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway. ( Jun, EK; Kim, B; Kim, H; Moon, JH; Noh, JY; Oh, C; Oh, S; Park, G; Song, HJ; Yoon, BS; You, S, 2008) |
| "Mitomycin C (MC) is an anti-neoplastic agent with an anti-proliferative effect on fibroblasts." | 5.33 | Use of mitomycin C for treatment of keloid: a preliminary report. ( Kronenberg, J; Orenstein, A; Talmi, YP; Wolf, M, 2005) |
| "Keloids are proliferative growths of dermal collagen, usually resulting from excessive tissue response during wound healing." | 5.33 | Up-regulation of metallothionein isoforms in keloid keratinocytes. ( Bay, BH; Lim, D; Phan, TT; Yip, GW, 2006) |
| "Mitomycin-C is a chemotherapeutic agent that inhibits DNA synthesis and fibroblast proliferation." | 5.33 | Application of mitomycin-C for head and neck keloids. ( Kim, JY; Stewart, CE, 2006) |
| "Keloids are the result of aberrant wound healing of human skin after dermal injury." | 5.32 | Effect of mitomycin C on keloid fibroblasts: an in vitro study. ( Alani, H; Simman, R; Williams, F, 2003) |
| "Transforming growth factor beta1 (TGF-beta1) plays a central role in wound healing and fibrosis and has been implicated in the pathogenesis of keloid disease and hypertrophic scar." | 5.32 | Genetic susceptibility to keloid disease and hypertrophic scarring: transforming growth factor beta1 common polymorphisms and plasma levels. ( Bayat, A; Bock, O; Ferguson, MW; Mrowietz, U; Ollier, WE, 2003) |
| "Keloids are benign mesenchymal tumours, usually present at and extending beyond the margins of sites of previous injury." | 5.32 | Topical application of imiquimod 5% cream to keloids alters expression genes associated with apoptosis. ( Berman, B; Jacob, SE; Nassiri, M; Vincek, V, 2003) |
| "Sphingosine (Sph) is a metabolite product of ceramide that has some different biochemical properties." | 5.32 | Sphingosine may have cytotoxic effects via apoptosis on the growth of keloid fibroblasts. ( Chang, SE; Choi, JH; Kim, KJ; Lim, YJ; Moon, KC; Ro, KH; Sung, KJ, 2004) |
| "Keloids are skin abnormalities that are characterized by excessive deposition of collagen bundles in the dermis." | 5.32 | Tretinoin reverses upregulation of matrix metalloproteinase-13 in human keloid-derived fibroblasts. ( Harii, K; Kitano, Y; Okazaki, M; Uchida, G; Yoshimura, K, 2003) |
| "Transforming growth factor beta (TGF beta) is a family of multifunctional cytokines, which play a central role in wound healing and fibrosis." | 5.31 | Genetic susceptibility to keloid disease and transforming growth factor beta 2 polymorphisms. ( Bayat, A; Bock, O; Ferguson, MW; Mrowietz, U; Ollier, WE, 2002) |
| "At 24 weeks, the recurrence rate of excised keloids treated with postoperative imiquimod 5% cream was lower than recurrence rates previously reported in the literature." | 5.31 | Pilot study of the effect of postoperative imiquimod 5% cream on the recurrence rate of excised keloids. ( Berman, B; Kaufman, J, 2002) |
| "The objective was to establish the safety and efficacy of intralesional 5-fluorouracil (5-FU) for the treatment of keloids and hypertrophic scars." | 5.30 | Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial. ( Ahmad, S; Khalid, FA; Mehrose, MY; Mujahid, AM; Rehman, SU; Saleem, M; Tarar, MN; Yousaf, MA, 2019) |
| "Six patients with previously untreated keloids were studied." | 5.30 | Major suppression of pro-alpha1(I) type I collagen gene expression in the dermis after keloid excision and immediate intrawound injection of triamcinolone acetonide. ( diLeonardo, M; Kauh, YC; Mondragon, G; Rouda, S; Tan, EM; Tokarek, R; Tuan, RS, 1997) |
| "We determined the rate of recurrence after excision alone (n = 43) and postoperative injection with triamcinolone acetonide (TAC; n = 65) or interferon alfa-2b (IFN-alpha 2b; n = 16)." | 5.30 | Recurrence rates of excised keloids treated with postoperative triamcinolone acetonide injections or interferon alfa-2b injections. ( Berman, B; Flores, F, 1997) |
| "Transforming growth factor beta (TGF-beta) has been implicated in the pathogenesis of keloids." | 5.30 | Expression of transforming growth factor beta 1, 2, and 3 proteins in keloids. ( Chau, D; Chin, GS; Gittes, GK; Kim, WJ; Lee, TY; Longaker, MT, 1999) |
| "The objective of this study was to compare the efficacy of post-excision intralesional 5-fluorouracil/triamcinolone acetonide (5-FU/TAC) and post-excision radiotherapy in the treatment of ear keloids." | 5.27 | The efficacy of excision followed by intralesional 5-fluorouracil and triamcinolone acetonide versus excision followed by radiotherapy in the treatment of ear keloids: A randomized control trial. ( Amin, M; Farooq, UK; Khalid, FA; Khan, KU; Mehrose, Y; Rabbani, J; Saleem, M; Tarar, MN, 2018) |
| "Our results did not support verapamil's capability in treatment of keloid nor hypertrophic scars." | 5.27 | Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial. ( Abedini, R; Mahmoudi, HR; Nasimi, M; Sasani, P; Shadlou, Z; Teymourpour, A, 2018) |
| "Intralesional triamcinolone acetonide, intralesional triamcinolone acetonide with hyaluronidase, and intralesional radiofrequency with triamcinolone acetonide are effective modalities for the treatment of keloids." | 5.27 | A comparative study of various modalities in the treatment of keloids. ( Aggarwal, A; Raghukumar, S; Ravikumar, BC; Vinay, KN; Yashovardhana, DP, 2018) |
| "These scars have been treated in a variety of ways with the laser, and the results, which have been good, are reported." | 5.27 | Argon and carbon dioxide laser treatment of hypertrophic and keloid scars. ( Cromwell, TA; Henderson, DL; Mes, LG, 1984) |
| "Only 1 recurrence developed in a follow-up of twelve to sixty-two months." | 5.27 | The treatment of earlobe keloids by surgical excision and postoperative triamcinolone injection. ( Press, BH; Shons, AR, 1983) |
| "Keloid is conventionally treated with intra-lesional (IL) triamcinolone, which is highly operator dependent and has its own adverse effects." | 5.24 | A Randomized, Single-Blind Trial of Clobetasol Propionate 0.05% Cream Under Silicone Dressing Occlusion Versus Intra-Lesional Triamcinolone for Treatment of Keloid. ( Imran, FH; Ismail, R; Jamil, A; Nor, NM; Shah, SA, 2017) |
| "To study the benefit of applying topical anesthetics or a 1:1 mixture of 1% lidocaine and TA at the TA injection site to alleviate pain during keloid treatment." | 5.24 | A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial. ( Burusapat, C; Usanakornkul, A, 2017) |
| "A double-blind randomized controlled trial with a paired split-scar design compared verapamil, an L-type Ca2+ channel antagonist, and triamcinolone for prevention of keloid recurrence after excision." | 5.22 | Verapamil is Less Effective than Triamcinolone for Prevention of Keloid Scar Recurrence After Excision in a Randomized Controlled Trial. ( Alghamdi, M; Danielsen, PL; Fear, MW; Gankande, TU; Hool, LC; Manzur, M; Rea, SM; Stevenson, AW; Viola, HM; Wallace, HJ; Wood, FM, 2016) |
| "We conducted a randomized controlled trial to compare the therapeutic efficacy of intralesional triamcinolone acetonide (ILTA) in combination with carbon dioxide laser (Group 1) versus in combination with cryotherapy (Group 2) in the treatment of keloids." | 5.22 | Therapeutic Efficacy of Intralesional Steroid With Carbon Dioxide Laser Versus With Cryotherapy in Treatment of Keloids: A Randomized Controlled Trial. ( Behera, B; Kumari, R; Malathi, M; Thappa, DM, 2016) |
| "To compare single intra-operative versus an intra-operative and two post-operative injections of triamcinolone after wedge excision of keloids of helix." | 5.20 | Comparison of single intra operative versus an intra operative and two post operative injections of the triamcinolone after wedge excision of keloids of helix. ( Ahmad, H; Bashir, MM; Khan, FA; Yousaf, N, 2015) |
| "to assess the effects of injectable triamcinolone on keloid scars length, height and thickness, and on the number of cells undergoing apoptosis." | 5.20 | Effect of triamcinolone in keloids morphological changes and cell apoptosis. ( de Souza, C; de Vasconcelos, AC; dos Santos, JM; Nunes, TA, 2015) |
| "This prospective study evaluates an argon gas-based system for the treatment of keloids in a patient population including all Fitzpatrick skin types with a 1-year follow-up." | 5.19 | A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy. ( Bulstra, AE; Niessen, FB; van Leeuwen, MC; van Leeuwen, PA, 2014) |
| "To compare the use of intralesional triamcinolone acetonide and its combination with 5 flourouracil in the treatment of keloid and hypertrophic scars in terms of reduction in initial height of the scar." | 5.19 | Intralesional triamcinolone alone and in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Bashir, MM; Khan, FA; Khan, MA, 2014) |
| "To compare 5-fluorouracil (5-FU) tattooing and intralesional steroid for treatment of keloids." | 5.16 | Comparison of the efficacy of intralesional triamcinolone acetonide and 5-fluorouracil tattooing for the treatment of keloids. ( Sadeghinia, A; Sadeghinia, S, 2012) |
| "To determine the effects of topical mitomycin C (MC) on shave-removed wounds and fibroblasts of ear keloids." | 5.15 | Ear keloids as a primary candidate for the application of mitomycin C after shave excision: in vivo and in vitro study. ( Chi, SG; Kim, BS; Kim, DW; Kim, GW; Kim, JY; Kim, MB; Lee, SJ; Lee, WJ; Sohn, MY, 2011) |
| "To determine the tolerability and compare the efficacy of imiquimod 5% and vehicle cream in lowering keloid recurrence after shaving." | 5.14 | Treatment of keloid scars post-shave excision with imiquimod 5% cream: A prospective, double-blind, placebo-controlled pilot study. ( Berman, B; Harrison-Balestra, C; Perez, OA; Ramirez, C; Viera, M; Villa, A; Zell, D, 2009) |
| "To investigate whether intralesional injection of low-dose 5-fluorouracil (5-Fu) and corticosteroid can increase effective rate and decrease recurrence rate of surgically removed auricular keloid." | 5.14 | [Clinical study of auricular keloid treatment with both surgical excision and intralesional injection of low-dose 5-fluorouracil and corticosteroids]. ( Gao, Z; Liu, W; Song, N; Wu, XL, 2009) |
| "This in vivo study was conducted to evaluate the clinical effect of a topical gel containing onion extract, allantoin, and pentaglycan on hypertrophic scars and keloids." | 5.14 | Effect of allium cepa-allantoin-pentaglycan gel on skin hypertrophic scars: clinical and video-capillaroscopic results of an open-label, controlled, nonrandomized clinical trial. ( Campanati, A; Ganzetti, G; Giuliano, A; Giuliodori, K; Marconi, B; Offidani, A; Sandroni, L; Savelli, A, 2010) |
| "To compare intralesional triamcinolone acetonide (TAC) alone or combined with onion extract in keloidal and hypertrophic scars." | 5.13 | An open, randomized, controlled, comparative study of the combined effect of intralesional triamcinolone acetonide and onion extract gel and intralesional triamcinolone acetonide alone in the treatment of hypertrophic scars and keloids. ( Arca, E; Koc, E; Kurumlu, Z; Surucu, B, 2008) |
| "Triamcinolone acetonide intralesional injection (TAIL) has been used for the treatment of keloids, but only with limited success." | 5.13 | Effects of interferon-alpha2b on keloid treatment with triamcinolone acetonide intralesional injection. ( Kim, SE; Lee, AY; Lee, JH, 2008) |
| "The aim of this study was to conduct a meta-analysis of the effectiveness and safety of verapamil and TAC in the treatment of HSs and keloids." | 5.12 | Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials. ( Bi, H; Gu, L; Qin, Z; Wang, P; Wang, Q, 2021) |
| "TAC may be beneficial for the short-term treatment of hypertrophic scars and keloids; however, 5-FU, 5-FU+TAC, and verapamil may produce superior results for medium- and long-term treatments." | 5.12 | The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021) |
| "To explore the effect of intralesional injection of low concentration 5-fluorouracil (5-FU) on inhibition of angiogenesis of keloid." | 5.12 | [Clinical study on keloid treatment with intralesional injection of low concentration 5-fluorouracil]. ( Cao, YL; Liu, W; Wu, XL, 2006) |
| "To investigate whether topical imiquimod 5% cream applied postoperatively after tangential excision can prevent recurrence of earlobe keloids." | 5.12 | Successful treatment of earlobe keloids with imiquimod after tangential shave excision. ( Stashower, ME, 2006) |
| "To evaluate the efficacy of 5% imiquimod cream in the prevention of recurrence of excised keloids." | 5.12 | The efficacy of 5% imiquimod cream in the prevention of recurrence of excised keloids. ( Chuangsuwanich, A; Gunjittisomram, S, 2007) |
| "To evaluate the efficacy and side effects of 5-fluorouracil (5-FU) as a therapeutic agent in the treatment of keloids of any duration or size." | 5.11 | Intralesional 5-fluorouracil as a treatment modality of keloids. ( Nanda, S; Reddy, BS, 2004) |
| "To compare the clinical response of keloidal and hypertrophic scars after treatment with intralesional corticosteroid alone or combined with 5-fluorouracil (5-FU), 5-FU alone, and the 585-nm flashlamp-pumped pulsed-dye laser (PDL)." | 5.10 | Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments. ( Fitzpatrick, RE; Manuskiatti, W, 2002) |
| "This clinical study determines the effectiveness of verapamil hydrochloride on the prevention and treatment of keloids." | 5.10 | Prevention and treatment of keloids with intralesional verapamil. ( Baroni, A; Brongo, S; D'Andrea, F; Ferraro, G, 2002) |
| "The possibility of altering the pathophysiology of keloid scars was investigated in 11 patients, using a single application of 5-fluorouracil solution for 5 minutes after extralesional excision was performed." | 5.09 | The effects of a single dose of 5-fluorouracil on keloid scars: a clinical trial of timed wound irrigation after extralesional excision. ( Chapman, P; Kakar, S; Khan, U; McGrouther, AD; Talas, G; Uppal, RS, 2001) |
| "It appears that TAC is more effective than verapamil for improving scar pliability and vascularity in keloids and hypertrophic scars after 3 weeks of treatment." | 5.05 | The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis. ( Fu, ZH; Guo, GH; Jiang, ZY; Liao, XC; Liu, MZ; Min, DH, 2020) |
| " The predictor variables were mitomycin C (MC) and imiquimod cream treatment after keloid excision." | 4.95 | Efficacy of 2 Representative Topical Agents to Prevent Keloid Recurrence After Surgical Excision. ( Lee, NH; Roh, SG; Shin, JY; Yang, KM; Yun, SK, 2017) |
| " Predictor variables were 5-fluorouracil (5-FU) or triamcinolone adjuvant therapy, and the outcome variable was keloid recurrence rate." | 4.93 | Could 5-Fluorouracil or Triamcinolone Be an Effective Treatment Option for Keloid After Surgical Excision? A Meta-Analysis. ( Kim, JS; Shin, JY, 2016) |
| " The recurrence rate after surgical excision of an ear keloid in the triamcinolone group was estimated as 15." | 4.93 | A Comparison of the Effectiveness of Triamcinolone and Radiation Therapy for Ear Keloids after Surgical Excision: A Systematic Review and Meta-Analysis. ( Lee, JW; Lee, NH; Roh, SG; Shin, JY; Yang, KM, 2016) |
| "Mitomycin C (MMC) is an antineoplastic antibiotic that has been used off-label in the treatment of hypertrophic scars and keloids." | 4.89 | Mitomycin C in the treatment of keloids: a case and review. ( Chotzen, VA; Kilmer, SL; Kleinerman, R, 2013) |
| "To describe the method for using imiquimod 5% cream in the prevention of keloid recurrence after surgery." | 4.82 | Imiquimod 5% cream for keloid management. ( Berman, B; Villa, A, 2003) |
| "The purpose of this study was to investigate the efficacy of surgery combined with triamcinolone acetonide injection in managing the difficult problem of keloid formation after syndactyly release." | 4.31 | Surgical excision and skin grafting combined with intralesional injection of triamcinolone for the treatment of keloids after syndactyly release. ( Du, X; Jiang, Y; Sun, W; Tian, J; Wang, B; Zhou, S, 2023) |
| "We investigated treatment outcomes of intralesional triamcinolone acetonide (IL TAC) compared with combination IL TAC and cryotherapy, including changes in pruritus, pain, and keloid size." | 4.31 | Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids. ( Banner, L; Cohen, AJ; Gleason, L; Lazarevic, B; Malkani, K; Nikbakht, N; Talasila, S; Uitto, J, 2023) |
| "To clarify the dosimetric characteristics of a real-time variable shape rubber-containing tungsten (STR) bolus in a clinical plan and investigate the efficacy of the STR bolus in photon radiotherapy for keloids and other superficial tumors." | 4.31 | Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors. ( Monzen, H; Nakamura, K; Nishimura, Y; Sakai, Y; Tamura, M, 2023) |
| "The patient underwent a 2-stage re-resection of the keloid, followed by postoperative radiotherapy, and triamcinolone acetonide injection around the incision at the time of the second operation." | 4.31 | Comprehensive treatment of ear keloid: A case report. ( Cai, XN; Ji, YC; Wang, MM, 2023) |
| "When comparing with topical lidocaine/prilocaine (EMLA) cream, a 1:1 mixture of 1% lidocaine and epinephrine significantly alleviated pain during and after the corticosteroid injection." | 4.31 | Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study. ( Park, TH, 2023) |
| "We retrospectively analysed the combined application of bleomycin and triamcinolone for the treatment of keloids and hypertrophic scars." | 4.31 | The combined application of bleomycin and triamcinolone for the treatment of keloids and hypertrophic scars: An effective therapy for treating refractory keloids and hypertrophic scars. ( Luo, QF, 2023) |
| "This study aimed to evaluate the efficacy of photodynamic therapy (PDT) with topical indocyanine green (ICG) in the treatment of keloid lesions." | 4.12 | Evaluating the efficacy of photodynamic therapy with indocyanine green in the treatment of keloid. ( Ahmadpour, F; Fakhraei, S; Hoseininezhad, M; Rajabi, O; Sazgarnia, A; Taheri, AR; Zamiri, F, 2022) |
| " Four differentially expressed metabolites including palmitoylcarnitine, sphingosine, phosphocholine, and phenylalanylisoleucine, were discovered to be related to keloid risk in the training and test cohorts." | 4.12 | Landscape of circulating metabolic fingerprinting for keloid. ( Chen, H; Chen, K; Chen, L; Hu, Y; Huang, D; Jin, S; Ju, M; Li, R; Liu, L; Luan, C; Wang, Z; Zhang, J; Zhou, X, 2022) |
| "Intralesional triamcinolone is a gold standard in treating the keloids in comparison with its effectiveness versus intralesional 5-fluorouracil intralesional verapamil and intralesional platelet-rich plasma." | 4.12 | Assessment of various intralesional injections in keloid: comparative analysis. ( Albalat, W; Khattab, F; Nabil, S, 2022) |
| "The histopathological changes and immunohistochemical studies occurring in keloids in vivo after treatment by intralesional (IL) verapamil are not yet assessed." | 4.02 | Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study. ( Abou-Taleb, DAE; Badary, DM, 2021) |
| "A retrospective chart review of 11 patients with 14 earlobe keloids treated with excision using a 980 nm laser diode followed by triamcinolone acetonide infiltration, between January 2015 and May 2016." | 4.02 | Experience Treating Earlobe Keloids with Laser Diode 980nm Excision Followed by Triamcinolone Infiltration. ( Fuenmayor, P; Pujadas, Z; Quiñonez, H; Salas, R, 2021) |
| "A case report of massive mandibular keloid with severe infection induced by acne achieved resolution of skin lesions after combined treatment with surgery and high concentration single-dose 5-aminolevulinic acid photodynamic therapy (5-ALA PDT)." | 4.02 | A massive mandibular keloid with severe infection: What is your treatment? ( Chen, XD; Gao, LM; Wu, XY; Zhao, LT, 2021) |
| "We investigated the dosimetric characteristics of electron radiotherapy for auricular keloid using real-time variable-shape tungsten rubber (STR)." | 4.02 | First Clinical Experience of Tungsten Rubber Electron Adaptive Therapy With Real-time Variable-shape Tungsten Rubber. ( Amano, M; Kawai, Y; Kosugi, T; Monzen, H; Tamura, M, 2021) |
| "Individualized surgery combined with early postoperative radiotherapy and triamcinolone acetonide injection is an ideal treatment method to ensure good auricular appearance, low incidences of complications and recurrence based on effective treatment of auricular keloids." | 4.02 | Individualized surgery combined with radiotherapy and triamcinolone acetonide injection for the treatment of auricular keloids. ( Guo, S; Sun, Q; Tong, S; Yu, ET; Zhou, KJ; Zhou, Y, 2021) |
| "To assess the effects of curcumol on the proliferation, apoptosis and collagen synthesis of keloid fibroblasts and explore the underlying mechanism." | 4.02 | [Curcumol inhibits keloid fibroblast proliferation and collagen synthesis through the ERK signaling pathway]. ( Sun, H; Wang, J; Yu, L; Yuan, W, 2021) |
| "Intralesional injection of triamcinolone acetonide is an effective method for treating keloids." | 3.96 | Evaluation of the efficacy of triamcinolone acetonide in the treatment of keloids by high-frequency ultrasound. ( Cai, L; Hu, M; Li, Z; Lin, L; Liu, J; Zheng, T, 2020) |
| " However, the effect of PDT mediated by the photosensitizer hematoporphyrin monomethyl ether (HMME) on keloids is not known well." | 3.96 | Hematoporphyrin monomethyl ether-mediated photodynamic therapy inhibits the growth of keloid graft by promoting fibroblast apoptosis and reducing vessel formation. ( Chen, X; Cui, X; Wu, X; Xu, P; Yang, S; Yao, X; Zhu, J; Zhu, W, 2020) |
| "Intralesional 5-fluorouracil (5-FU) in combination with triamcinolone acetonide (TAC) has been recommended as a promising alternative for keloids not responding to silicone-based products, cryotherapy or intralesional corticosteroids alone." | 3.96 | Treatment of keloids using 5-fluorouracil in combination with crystalline triamcinolone acetonide suspension: evaluating therapeutic effects by using non-invasive objective measures. ( Gauglitz, GG; Guertler, A; Poetschke, J; Reinholz, M; Schwaiger, H, 2020) |
| "We aimed to evaluate the clinical outcomes of intralesional excision followed by postoperative triamcinolone acetonide intralesional injection (TA ILI) as auricular keloid treatments." | 3.96 | Auricular keloid management in Asian skin: Clinical outcome of intralesional excision and postoperative triamcinolone acetonide intralesional injection. ( Choi, YJ; Kim, WS; Lee, GY; Lee, HJ; Lee, YH, 2020) |
| "The current experiment was performed to investigate whether luteolin affects the proliferation and apoptosis of keloid fibroblasts by regulating the expression of FRAT1 gene." | 3.96 | Luteolin affects keloid fibroblast proliferation and apoptosis by regulating FRAT1 gene expression. ( Liu, W; Wei, S; Zhang, X, 2020) |
| " Combination therapy of intralesional 5-fluorouracil and triamcinolone offers efficacious treatment for keloids with a reduced adverse effect of the drug monotherapy." | 3.96 | Potentials for implementing pressure-controlled jet injection in management of keloids with intralesional 5FU and corticosteroids. ( Artzi, O; Levenberg, A; Vinshtok, Y, 2020) |
| " Targeting aberrant glucose metabolism with shikonin, a pyruvate kinase M2 inhibitor, dampened NLRP3-mediated inflammation (cleaved caspase-1 [P < 0." | 3.96 | Regulation of glycolysis and the Warburg effect in wound healing. ( Abdullahi, A; Auger, C; Barayan, D; Jeschke, MG; Vinaik, R, 2020) |
| "Triamcinolone acetonide intralesional injections significantly increased apoptosis in keloids, represented by increased caspase 3 protein and TUNEL expressions, supporting that steroids suppress keloids in part owing to enhancement of apoptosis." | 3.91 | Triamcinolone Acetonide Suppresses Keloid Formation Through Enhancing Apoptosis in a Nude Mouse Model. ( Chen, AD; Chen, RF; Huang, YT; Kuo, YR; Lai, CS; Li, YT; Lin, SD, 2019) |
| "After intralesional injection of triamcinolone acetonide, most of the hypertrophic scars and keloids improved in color, thickness, softness, and vascular distribution." | 3.91 | Comparative efficacy of intralesional triamcinolone acetonide injection during early and static stage of pathological scarring. ( Ao, M; Fu, Q; Huang, L; Song, H; Tan, J, 2019) |
| "We retrospectively studied the efficacy of personalized therapy with surgical resection plus prophylactic management of postsurgical auricular keloids by intralesional injection of betamethasone and local pressure therapy using magnets in patients with auricular keloids." | 3.91 | A multimodal therapeutic approach improves the clinical outcome of auricular keloid patients. ( Hao, T; Hao, YH; Li, CX; Xie, F; Xing, XJ; Yang, Y; Zhao, ZG, 2019) |
| "To evaluate the effectiveness of combined ablative fractional CO2 laser and topically applied 5-fluorouracil (5-FU) or verapamil hydrochloride in the treatment of hypertrophic scars (HTSs) and keloids and to examine their possible effects on TGF-β1 expression." | 3.91 | The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study. ( Abd El Azez, TA; Abdel Rahman, SH; Hussein, MS; Sabry, HH; Sanad, RR, 2019) |
| "This was an in vitro study using a primary culture of keloid fibroblasts in which ibuprofen was used to inhibit HIF-1α expression." | 3.91 | Role of Hypoxia Inducible Factor-1 Alpha (HIF-1α) in Cytoglobin Expression and Fibroblast Proliferation of Keloids. ( Hardiany, NS; Jusman, SWA; Ningsih, SS; Sadikin, M; Sari, DH, 2019) |
| "We conducted this experimental study to analyze the relationship between sphingosine-1-phosphate (S1P)-induced mitogen-activated protein (MAP) kinase pathways and keloid formation." | 3.91 | Association between sphingosine-1-phosphate-induced signal transduction via mitogen-activated protein kinase pathways and keloid formation. ( Chung, H; Jo, DI; Jung, SH; Kim, B; Kim, SH; Ko, HM; Lee, DH; Lee, SH; Song, YK, 2019) |
| "To create three-dimensional poly lactic-co-glycolic acid (PLGA) scaffolds containing autologous platelet-rich plasma (PRP) as an in vitro culture environment for keloid fibroblasts (KL), and to study their implantation into nude mice to mimic the process of keloid formation." | 3.88 | Three-dimensional poly lactic-co-glycolic acid scaffold containing autologous platelet-rich plasma supports keloid fibroblast growth and contributes to keloid formation in a nude mouse model. ( Chen, C; Li, F; Luo, S; Sun, Z; Wang, H; Xu, X; Zhu, G, 2018) |
| "Fifteen patients with keloids were treated with cryotherapy and intralesional injections of triamcinolone acetonide for a total of 4 times at intervals of 4 weeks." | 3.88 | Evaluating the Therapeutic Success of Keloids Treated With Cryotherapy and Intralesional Corticosteroids Using Noninvasive Objective Measures. ( Gauglitz, G; Poetschke, J; Reinholz, M; Ruzicka, T; Schwaiger, H, 2018) |
| "The aim of this study was to evaluate the effect of intralesional tamoxifen on keloids, particularly on the concentration of fibroblasts, dermal inflammatory infiltrate, and collagen degeneration." | 3.85 | Morphological and morphometric analysis of the effects of intralesional tamoxifen on keloids. ( Alencar, AP; da Silva, BB; Filho, LL; Soares-Lopes, IM; Soares-Lopes, LR, 2017) |
| " Moreover, Diprotin A significantly suppressed proliferation and extracellular matrix secretion of CD26+ fibroblasts isolated from keloid tissues." | 3.85 | Expansion of CD26 positive fibroblast population promotes keloid progression. ( Bogari, M; Chai, G; Chen, W; Chen, X; Lin, L; Mar Aung, Z; Qu, M; Wang, X; Xin, Y; Zhang, Y; Zhu, M, 2017) |
| "The authors recruited 40 patients with 58 keloids who were scheduled to undergo intralesional triamcinolone acetonide (TA) injections." | 3.85 | Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment. ( Chung, WS; Hong, JY; Kim, BJ; Kim, MN; Lee, Y; Park, KY, 2017) |
| "To explore the effect of simvastatin on the proliferation, apoptosis and protein expressions of keloid fibroblasts under normoxia,hypoxia or TGF-β1 treatment." | 3.83 | [Different effects of simvastatin on keloid fibroblasts under hypoxia and TGF-β1 treatment]. ( An, Y; Chen, B; Kang, C; Qin, Z; Yu, D; Zhao, X, 2016) |
| "The aim of this study was to analyse the effect of captopril on collagen metabolisms in keloid fibroblast cells, and to provide information for the mechanism and therapy of keloid." | 3.83 | Effect of captopril on collagen metabolisms in keloid fibroblast cells. ( Cen, Y; Chen, J; Liu, Y; Nicolas, C; Zhao, S, 2016) |
| "The aim of this study was to investigate the prevalences of hypertrophic scars and keloids in acne patients treated with oral isotretinoin." | 3.83 | Observational retrospective study evaluating the effects of oral isotretinoin in keloids and hypertrophic scars. ( Bagatin, E; Gonçalves, RG; Guadanhim, LR, 2016) |
| "The authors evaluated the recurrence rate of therapy-resistant keloids treated with excision followed by radiotherapy (1200 Gy in three or four fractions)." | 3.82 | The results of surgical excision and adjuvant irradiation for therapy-resistant keloids: a prospective clinical outcome study. ( Kreulen, M; Oldenburger, F; van de Kar, AL; van Zuijlen, PPM, 2007) |
| "To investigate the effect of 8-aminolevulinic acid (ALA) photodynamic therapy (PDT) on the cell proliferation, apoptosis and collagen secretion in keloid fibroblasts and to provide the theoretical base for ALA-PDT treatment of keloids." | 3.81 | [Effect of photodynamic therapy on the cell proliferation and collagen secretion of keloid fibroblasts]. ( Fan, Y; Jiao, J, 2015) |
| "We compared the expression and activity of chymase in keloids and normal skin tissues using Western blotting and radioimmunoassay, and studied the expression of TGF-β1, interleukin-1β, collagen I, hydroxyproline, and angiotensin II in KFs after chymase and inhibitors' treatment." | 3.81 | Role of chymase in the local renin-angiotensin system in keloids: inhibition of chymase may be an effective therapeutic approach to treat keloids. ( Cen, Y; Chen, J; Wang, R; Zhang, Z, 2015) |
| " In the present study, PDT involving hematoporphyrin monomethyl ether (HMME) was applied to keloid fibroblasts (KFB), and the effects and the mechanism of action were explored." | 3.81 | Photodynamic Therapy-Induced Apoptosis of Keloid Fibroblasts is Mediated by Radical Oxygen Species In Vitro. ( Li, J; Li, L; Li, X; Wang, X, 2015) |
| "To investigate the effect of Metformin on the proliferation and collagen synthesis of the human keloids fibroblasts as well as the effect on phosphorylation of Akt/FoxO1 signal transduction pathway." | 3.81 | [The effect of Metformin on the proliferation and collagen synthesis of human keloids fibroblasts]. ( Weiyuan, M; Yi, S, 2015) |
| "To determine and compare the effectiveness of silicone gel and tretinoin cream for the prevention of hypertrophic scars and keloids resulting from postoperative wounds and for scar improvement." | 3.80 | Comparative effect of topical silicone gel and topical tretinoin cream for the prevention of hypertrophic scar and keloid formation and the improvement of scars. ( Kwon, SY; Park, K; Park, SD, 2014) |
| "To investigate the treatment of auricular keloid with dinuclear surgery and intralesional injection of compound Betamethasone." | 3.80 | [Treatment of auricular keloids with surgery and intralesional injection of compound betamethasone]. ( Li, W; Liao, H; Liu, W; Wang, F; Yang, H, 2014) |
| "Present studies explored whether and how the L-ascorbic acid derivative (+) sodium L-ascorbate (SA) would affect production of collagen and elastic fibers in cultures of fibroblasts derived from normal human skin and dermal fat, as well as in explants of normal human skin, stretch-marked skin and keloids." | 3.80 | Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. ( Hinek, A; Kim, HJ; Mitts, TF; Wang, A; Wang, Y, 2014) |
| "This study designs an alternative transdermal delivery system for 10,11-methylenedioxycamptothecin(MD-CPT) to inhibit keloid." | 3.80 | Transdermal delivery of 10,11-methylenedioxycamptothecin by hyaluronic acid based nanoemulsion for inhibition of keloid fibroblast. ( Chen, X; Cheng, X; Gao, T; Gao, Y; Kong, M; Li, P; Wang, J; Wang, Z, 2014) |
| "Keloids are managed using a variety of treatments, primarily triamcinolone and excision or destruction of a lesion." | 3.79 | Management of keloids in the United States, 1990-2009: an analysis of the National Ambulatory Medical Care Survey. ( Davis, SA; Feldman, SR; McMichael, AJ, 2013) |
| "The purpose of this study was to investigate the effects of tacrolimus on human fibroblasts derived from unwounded skin, hypertrophic scars (HTS), and keloids." | 3.79 | Tacrolimus fails to regulate collagen expression in dermal fibroblasts. ( Januszyk, M; Kuang, AA; Wong, VW; You, F, 2013) |
| "Preliminary clinical trials suggest a superior effect when steroids and 5-fluorouracil are injected together for the intralesional therapy of keloids." | 3.79 | A study of the combination of triamcinolone and 5-fluorouracil in modulating keloid fibroblasts in vitro. ( Burd, A; Cai, YJ; Huang, L; Leung, BC; Lung, I, 2013) |
| "The effects of locally produced chitosan (CPSRT-NC-bicarbonate) in the intervention of keloid pathogenesis were investigated in vitro." | 3.79 | Keloid pathogenesis via Drosophila similar to mothers against decapentaplegic (SMAD) signaling in a primary epithelial-mesenchymal in vitro model treated with biomedical-grade chitosan porous skin regenerating template. ( Halim, AS; Lim, CK; Noorsal, K; Yaacob, NS; Zainol, I, 2013) |
| "To describe a 1-year follow-up of 12 patients with earlobe keloids treated by shaving followed by cryosurgery and intralesional injection of triamcinolone." | 3.79 | Combined treatment of earlobe keloids with shaving, cryosurgery, and intralesional steroid injection: a 1-year follow-up. ( Careta, MF; Fortes, AC; Maruta, CW; Messina, MC, 2013) |
| "To investigate the efficacy of topical and intralesional mitomycin C for the treatment of keloids and HTS." | 3.78 | Treatment of keloids and hypertrophic scars using topical and intralesional mitomycin C. ( Seo, SH; Sung, HW, 2012) |
| "To study the effects of oxymatrine (OM) on the expressions of pro-collagen I (PC I), pro-collagen II (PC III), fibronectin (FN), matrix metalloproteinase-1 (MMP-1) mRNA of fibroblasts from keloid (KFb), hyperplastic scar (HFb), and normal skin (NFb), and to compare with hydrocortisone (HC)." | 3.78 | [Effects of oxymatrine on the expressions of pro-collagen and fibronectin of fibroblasts derived from human hyperplastic scars]. ( Bian, X; Nie, XJ; Wu, JQ, 2012) |
| "Methanolic extraction of honey has positive anti proliferative effect on keloid fibroblasts in a dose-dependent manner." | 3.77 | Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts. ( Gan, SH; Halim, AS; Nurul Syazana, MS; Shamsuddin, S, 2011) |
| "In this study, we evaluated the in vitro cytotoxic effect of PDT at 5J/cm(2) and 10J/cm(2) of red light (633 ± 3nm) using 5-aminolevulinic acid (ALA) and methyl aminolevulinate (MAL) with and without DW, on keloid fibroblasts compared to normal skin fibroblasts." | 3.77 | Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy. ( Allan, D; Allan, E; Bayat, A; Colthurst, J; Sebastian, A, 2011) |
| "A 2-year-old boy with bilateral corneal keloid was treated with lamellar keratoplasty and tranilast eye drops." | 3.77 | Long-term follow-up after lamellar keratoplasty in a patient with bilateral idiopathic corneal keloid. ( Chikama, T; Fukuda, K; Nishida, T; Takahashi, M, 2011) |
| "The optimal treatment for keloids remains undefined." | 3.77 | In search of the optimal treatment of keloids: report of a series and a review of the literature. ( Lawrence, WT, 1991) |
| " Five and 2 months before presentation, she was treated with intradermal triamcinolone acetonide for keloid scars." | 3.76 | Cushing's syndrome and adrenal insufficiency after intradermal triamcinolone acetonide for keloid scars. ( Finken, MJ; Mul, D, 2010) |
| "Intralesional injection of low-dose 5-fluorouracil (5-FU) has recently been used as an experimental modality for treating keloid scarring and has shown promising efficacy in improving scar appearance and preventing recurrence of the keloid." | 3.76 | Low-dose 5-fluorouracil induces cell cycle G2 arrest and apoptosis in keloid fibroblasts. ( Burd, A; Cai, YJ; Huang, L; Leung, CS; Lung, I; Wong, YP, 2010) |
| "To investigate the effect of the PPAR-gamma agonist troglitazone on transforming growth factor (TGF)-beta1-induced collagen type I expression in keloid fibroblasts." | 3.75 | Troglitazone suppresses transforming growth factor-beta1-induced collagen type I expression in keloid fibroblasts. ( Chen, XL; Gao, WY; Guo, SZ; Li, X; Li, ZJ; Ma, B; Yi, CG; Zhang, GY, 2009) |
| "Pretreatment with 60% lidocaine tape significantly reduces the pain associated with intralesional injection of TA." | 3.75 | Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid. ( Hyakusoku, H; Murakami, M; Tosa, M, 2009) |
| "To evaluate the efficacy of topical imiquimod 5% cream applied after surgical excision and primary closure of trunk keloids in the prevention of recurrence." | 3.75 | Failure of imiquimod 5% cream to prevent recurrence of surgically excised trunk keloids. ( Cação, FM; Messina, MC; Tanaka, V, 2009) |
| "To study the expression and function of sphingosine kinase (SphK) 1 and SphK2 in human keloid fibroblasts." | 3.75 | [Expression and function of sphingosine kinases 1 and 2 in human keloid fibroblasts]. ( Cai, JL; Liu, ZZ; Wang, LX; Wang, W; Xu, B; Zhang, J; Zhang, JX, 2009) |
| "The purpose of this study was to report severe keloids caused by hydrogen cyanide injury." | 3.74 | Severe keloids caused by hydrogen cyanide injury: a case report. ( Guo, G; Jian, X; Lin, D; Ruan, Y; Zhao, B, 2008) |
| "To determine whether application of mitomycin C to the base of shave-removed keloids would prevent their recurrence." | 3.74 | Application of topical mitomycin C to the base of shave-removed keloid scars to prevent their recurrence. ( Bailey, JN; Clayton, WJ; Rustin, MH; Waite, AE, 2007) |
| "To examine the effect of aspirin on the tumor necrosis factor (TNF)-alpha-induced NF-kappaB activation in keloid fibroblasts." | 3.74 | Abnormal nuclear factor (NF)-kappaB signal pathway and aspirin inhibits tumor necrosis factor alpha-induced NF-kappaB activation in keloid fibroblasts. ( Cai, J; Xu, B; Zhang, J; Zhao, Y; Zhu, G, 2007) |
| "Imiquimod 5% cream has been found to be effective and safe in preventing recurrence of keloids on earlobes after excision." | 3.74 | Imiquimod 5% cream for the prevention of recurrence after excision of presternal keloids. ( Gupta, S; Khaitan, BK; Malhotra, AK; Sharma, VK, 2007) |
| "This study was set out to investigate the effects of a novel selective NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), on keloid fibroblasts." | 3.74 | DHMEQ, a novel NF-kappaB inhibitor, suppresses growth and type I collagen accumulation in keloid fibroblasts. ( Hirano, A; Makino, S; Mitsutake, N; Nakashima, M; Ohtsuru, A; Saenko, VA; Tanaka, K; Umezawa, K; Yamashita, S, 2008) |
| "To investigate the relations between thymosin beta 4 and pathologic scars by comparing the mRNA levels of thymosin beta 4 in keloid, hypertrophic scar and normal skin." | 3.73 | [Expression of thymosin beta 4 mRNA expression in keloid tissues and fibroblasts cultured from keloid and its significance]. ( Nie, FF; Qin, ZL; Wu, JQ, 2005) |
| "83 keloids of 66 patients had been irradiated after excision by a uniform protocol with 4 x 5 Gy (strontium- 90 [(90)Sr] surface applicator)." | 3.73 | Results of postoperative (90)Sr radiotherapy of keloids in view of patients' subjective assessment. ( Böttcher, HD; Fraunholz, IB; Gerstenhauer, A, 2005) |
| "To establish the safety and efficacy of imiquimod 5% cream in the prevention of recurrences of excised earlobe keloids." | 3.73 | Postsurgical use of imiquimod 5% cream in the prevention of earlobe keloid recurrences: results of an open-label, pilot study. ( Busquets, AC; Martin-García, RF, 2005) |
| "Transforming growth factor beta 1 (TGF-beta1) upregulation has been implicated in hypertrophic scars and keloids, but it is unclear if it is the cause or an effect of excessive scar formation." | 3.73 | Upregulation of TGF-beta1 expression may be necessary but is not sufficient for excessive scarring. ( Bruder, JM; Campaner, AB; Cusick, JL; Ferreira, LM; Gragnani, A; Morgan, JR, 2006) |
| "We studied the long-term outcome of injection of triamcinolone acetonide into keloid scars in Asian patients." | 3.73 | Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients. ( Hata, Y; Igawa, HH; Ito, O; Muneuchi, G; Onodera, M; Suzuki, S, 2006) |
| "Isotretinoin-induced keloid formation has occasionally been reported in patients who have undergone dermabrasion or laser treatment." | 3.73 | Possible isotretinoin-induced keloids in a patient with Behçet's disease. ( Dogan, G, 2006) |
| "To investigate the effects of quercetin and X-ray on collagen synthesis of cultured human keloid-derived fibroblast and the mechanism." | 3.73 | Influence of quercetin and x-ray on collagen synthesis of cultured human keloid-derived fibroblasts. ( Long, X; Wang, XJ; Zeng, X; Zhang, FQ, 2006) |
| "We have assessed the in vitro effects of quercetin on proliferation, collagen synthesis and the expression of the IGF system in keloid-derived fibroblasts." | 3.72 | Suppression of insulin-like growth factor signalling pathway and collagen expression in keloid-derived fibroblasts by quercetin: its therapeutic potential use in the treatment and/or prevention of keloids. ( Chan, SY; Huynh, H; Lee, ST; Nguyen, TT; Phan, TT; See, P; Tran, E, 2003) |
| "The content of hydroxyproline was determined and the expression of connective tissue growth factor gene was detected by the reverse transcription-polymerase chain reaction and image analysis technique in 5 normal skins, 15 hypertrophic scars and 7 keloid tissues." | 3.72 | [Expression of connective tissue growth factor gene in the hypertrophic scar and keloid tissue]. ( Ji, SX; Li, SR; Liu, JY, 2003) |
| "The purpose of this study is 3-fold: to review our cases of keloid formation after syndactyly release, to report a clinical association between primary enlargement of the digits and risk of keloid formation, and to report treatment using low-dose, short-term methotrexate as an adjunct to revision surgery." | 3.72 | Keloid formation after syndactyly reconstruction: associated conditions, prevalence, and preliminary report of a treatment method. ( Carter, PR; Ezaki, M; Masson, J; Muzaffar, AR; Rafols, F, 2004) |
| " In this study, the effects of glucose, fructose, galactose and mannose on type I and type III collagen gene expression and synthesis were studied in granulation tissue, hypertrophic scar and keloid fibroblast cultures." | 3.72 | Hexose sugars differentially alter collagen gene expression and synthesis in fibroblasts derived from granulation tissue, hypertrophic scar and keloid. ( Kössi, J; Laato, M; Peltonen, J; Risteli, J; Vähä-Kreula, M, 2004) |
| "We performed a retrospective chart review of 3 pediatric patients who developed Cushing's syndrome after local administration of triamcinolone acetonide (TCA)." | 3.72 | Cushing's syndrome after intra-articular and intradermal administration of triamcinolone acetonide in three pediatric patients. ( Kumar, S; Lteif, AN; Reed, AM; Singh, RJ, 2004) |
| "Fibrosis is characterized by an excessive accumulation of collagen which contains increased levels of pyridinoline cross-links." | 3.72 | Increased formation of pyridinoline cross-links due to higher telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon. ( Bank, RA; Boers, W; DeGroot, J; Huizinga, TW; Karel Ronday, H; Middelkoop, E; Ulrich, MM; van den Bogaerdt, AJ; van der Slot, AJ; Zuurmond, AM, 2004) |
| "Quercetin significantly inhibited the expression of TGF-beta receptors 1 and 2 in keloid fibroblasts at three concentrations (low, medium, and high)." | 3.72 | Suppression of transforming growth factor beta/smad signaling in keloid-derived fibroblasts by quercetin: implications for the treatment of excessive scars. ( Chan, SY; Lee, ST; Lim, IJ; Longaker, MT; Phan, TT; Tan, EK, 2004) |
| "Human normal and keloid dermal fibroblasts were propagated in a serum-free in vitro model with exposure to 0, 5, 10, or 20 microm triamcinolone acetonide for 0, 24, 72, or 96 hours." | 3.71 | Triamcinolone stimulates bFGF production and inhibits TGF-beta1 production by human dermal fibroblasts. ( Carroll, LA; Hanasono, MM; Kita, M; Koch, RJ; Mikulec, AA, 2002) |
| "In this study, different molecular weight CM-chitosans were prepared and the effects on the growth and collagen secretion of normal skin fibroblasts and keloid fibroblasts were investigated in vitro." | 3.71 | The effect of carboxymethyl-chitosan on proliferation and collagen secretion of normal and keloid skin fibroblasts. ( Chen, XG; Liu, WS; Park, HJ; Wang, Z, 2002) |
| " In the present study the effects of biomedically relevant hexose sugars (glucose, fructose, galactose, mannose) and sucrose disaccharide on the expression of COX-1 and COX-2 genes were evaluated in granulation tissue fibroblasts, hypertrophic scar fibroblasts and keloid fibroblasts." | 3.71 | Differential effects of hexoses and sucrose, and platelet-derived growth factor isoforms on cyclooxygenase-1 and -2 mRNA expression in keloid, hypertrophic scar and granulation tissue fibroblasts. ( Kössi, J; Laato, M; Peltonen, J; Uotila, P, 2001) |
| "It has been found that infections, inappropriate supporter, allergy to nickel and gold, local delayed allergy are the chief factors to form keloides of the earlobes." | 3.70 | [Prevention of keloids of the earlobes]. ( Li, B; Liu, D; Tian, J; Zhou, C, 1999) |
| " A mutation in exon 5 resulting in amino acid substitution was found in 1 of the patients in keloid tissue and cultured keloid fibroblasts (codon 156, CGC-->CCC, arginine-->proline)." | 3.70 | Analysis of p53 gene mutations in keloids using polymerase chain reaction-based single-strand conformational polymorphism and DNA sequencing. ( Fivenson, D; Han, X; Hou, Z; Ladin, D; Olson, J; Saed, GM, 1998) |
| "The experimental drug pirfenidone (PFD) has been evaluated as an inhibitor of keloid proliferation and compared with triamcinolone (TAC) injections by studying the involution of active human keloid implants in athymic nude mice (nu-nu)." | 3.70 | Involution of keloid implants in athymic mice treated with pirfenidone or with triamcinolone. ( Bloom, RF; Margolin, SB; Shetlar, CL; Shetlar, DJ; Shetlar, MR, 1998) |
| "Intralesional injection of triamcinolone acetonide (TA) for the treatment of keloid is painful, and lidocaine-mixed preparations are much the same." | 3.70 | Pain-free intralesional injection of triamcinolone for the treatment of keloid. ( Ono, N, 1999) |
| "We have previously reported that tranilast, an anti-allergic agent, specifically suppresses collagen synthesis in normal skin fibroblasts and to a greater extent in keloid fibroblasts." | 3.69 | Tranilast inhibits collagen synthesis in normal, scleroderma and keloid fibroblasts at a late passage culture but not at an early passage culture. ( Nishikawa, T; Tajima, S; Yamada, H, 1995) |
| "The mechanical properties of 17 keloids in 9 patients before and during treatment with intralesional triamcinolone acetonide were studied using a recently developed noninvasive suction device for measuring skin elasticity in vivo." | 3.69 | Mechanical properties of keloids in vivo during treatment with intralesional triamcinolone acetonide. ( Krusche, T; Worret, WI, 1995) |
| "In this study, we evaluated the effects of isotretinoin and triamcinolone acetonide on the growth of keloid and embryonal human skin fibroblasts in vitro." | 3.69 | Inhibition of human keloid fibroblast growth by isotretinoin and triamcinolone acetonide in vitro. ( Cruz, NI; Korchin, L, 1994) |
| "Six fibroblast cell strains, derived from keloid or normal skin, exhibited similar growth responses to platelet-derived growth factor, transforming growth factor beta 1 (TGF-beta 1), gamma-interferon (gamma-IFN) and histamine." | 3.69 | Effects of various growth factors and histamine on cultured keloid fibroblasts. ( Kadono, T; Kikuchi, K; Takehara, K, 1995) |
| "Using a 3-dimensional fibrin gel model system simulating fibroplasia of wound repair, we investigated the interaction between keloid fibroblasts and fibrin matrix and compared it with that of normal fibroblasts." | 3.69 | Elevated levels of plasminogen activator inhibitor-1 may account for the altered fibrinolysis by keloid fibroblasts. ( Laug, WE; Nichter, LS; Nimni, ME; Sun, B; Tuan, TL; Zhu, JY, 1996) |
| "The feasibility of iontophoretic transdermal delivery of tranilast (N-(3,4-dimethoxycinnamoyl) anthranilic acid) for the treatment of keloid and hypertrophic scars was evaluated in hairless rats and humans." | 3.69 | Treatment of keloid and hypertrophic scars by iontophoretic transdermal delivery of tranilast. ( Ikuta, Y; Murakami, T; Shigeki, S; Yata, N, 1997) |
| " After surgery, 40 patients received 5 mg/kg/day of tranilast, which inhibits the collagen synthesis of keloid fibroblasts." | 3.69 | Factors affecting hypertrophic scar development in median sternotomy incisions for congenital cardiac surgery. ( Inoue, M; Irie, H; Mitani, H; Nakamura, K; Sano, S; Sunami, H, 1997) |
| "We studied the inhibitory effects of tranilast, an anti-allergic drug, on the human keloid tissues implanted into the dorsal skin of athymic nude mice and on the growth of keloid fibroblast in vitro." | 3.68 | [Effect of tranilast, an anti-allergic drug, on the human keloid tissues]. ( Arai, N; Hamano, S; Ichikawa, K; Kikuchi, S; Momose, Y; Shibata, N; Sugimoto, C; Suzawa, H; Tazawa, S; Tsuchiya, O, 1992) |
| "Treatment with transforming growth factor beta 1 (TGF-beta 1) results in stimulation of total protein synthesis in normal dermal fibroblasts but not in keloid fibroblasts, suggesting that the TGF-beta regulatory program is altered in keloid fibroblasts." | 3.68 | Keloid fibroblasts exhibit an altered response to TGF-beta. ( Babu, M; Diegelmann, R; Oliver, N, 1992) |
| "An attempt was made to assess the value of beta radiation alone or in combination with surgery, and of intralesional triamcinolone acetonide in treating 100 keloids and hypertrophic scars in 65 patients." | 3.68 | Evaluation of various methods of treating keloids and hypertrophic scars: a 10-year follow-up study. ( Chowdri, NA; Darzi, MA; Kaul, SK; Khan, M, 1992) |
| "Small proteoglycans (PGs), extracted from human keloid scar tissue with 4M guanidinium chloride and fractionated by DEAE-cellulose chromatography, were separated by ethanol precipitation into one L-iduronic acid-rich and one D-glucuronic acid-rich fraction." | 3.68 | Purification and characterization of iduronic acid-rich and glucuronic acid-rich proteoglycans implicated in human post-burn keloid scar. ( Burd, DA; Garg, HG; Lippay, EW; Neame, PJ, 1990) |
| "A potential therapeutic role of minoxidil in fibrotic or sclerotic conditions, such as keloids, has been suggested on the basis of its reported ability to inhibit the proliferation of human dermal fibroblasts." | 3.68 | [Effect of minoxidil on DNA synthesis in cultured fibroblasts from healthy skin or keloids]. ( De Moragas, JM; Martí, F; Piñol, G; Puig, L; Rueda, F, 1990) |
| "Argon and CO2 lasers have been used to treat 13 patients with well-established keloid scars of the trunk or earlobe." | 3.67 | Preliminary results of argon and carbon dioxide laser treatment of keloid scars. ( Apfelberg, DB; Lash, H; Maser, MR; Weston, J; White, D, 1984) |
| "Keloid fibroblasts were propagated in culture and their proliferative behaviour and response to the Epidermal Growth Factor (EGF) were studied." | 3.67 | Keloid fibroblasts in culture: abnormal growth behaviour and altered response to the epidermal growth factor. ( Harper, RA, 1989) |
| "We report the observation of delayed wound healing and keloid formation in three patients, following dermabrasion or Argon laser treatment administered while they were receiving isotretinoin for acne or rosacea." | 3.67 | Delayed wound healing and keloid formation following argon laser treatment or dermabrasion during isotretinoin treatment. ( Zachariae, H, 1988) |
| "The effects of ascorbic acid and hydrocortisone on activity of prolyl hydroxylase in fibroblasts from keloid and normal human dermis were investigated and compared to the effects of these agents on collagen synthesis." | 3.66 | Variation in prolyl hydroxylase activity of keloid-derived and normal human fibroblasts in response to hydrocortisone and ascorbic acid. ( Russell, JD; Russell, SB; Trupin, JS, 1983) |
| " Ten patients with massive keloids, resistant to conventional therapy by excision, grafting, and/or intralesional injection of steroids, have been treated by excising the keloid, grafting the defect, inducing lathyrism with Beta aminopropionitrile fumurate or penicillamine and administering colchicine." | 3.66 | Pharmacologic control of surface scarring in human beings. ( Peacock, EE, 1981) |
| " In the established hypertrophic scar or keloid, lesions of resonable size on the trunk can be treated with intralesional injections of triamcinolone only; lesions larger than 75 sq cm or facial lesions can be excised and closed or shaved and grafted, again with one or all of the above mentioned modalities being the control factor that modifies healing and prevents recurrence." | 3.65 | Hypertrophic scars and keloids. ( Ketchum, LD, 1977) |
| "A case of long-term Cushing's syndrome after intradermal injection of 160 mg of triamcinolone diacetate has been presented." | 3.65 | Cushing's syndrome associated with the intradermal injection of triamcinolone diacetate. ( Kolodny, SC; Langston, JR, 1976) |
| "A comparison of the rates of synthesis of collagen in normal skin, normal and hypertrophic scars, and keloids has been made by measuring the rate of incorporation of [14-C]-proline into peptide-bound [14-C]-hydroxyproline by tissue minces in vitro." | 3.65 | Collagen biosynthesis in normal human skin, normal and hypertrophic scar and keloid. ( Craig, RD, 1975) |
| "A method is described for the treatment of the linear keloid scar, by surgical excision and post-operative irradiation delivered locally to the base of the sutured edges of the scar, by an iridium-192 wire." | 3.65 | Keloid scars: a new method of treatment combining surgery with interstitial radiotherapy. ( Ellis, F; Malaker, A; Paine, CH, 1976) |
| " Increasing the dosage and duration of keloid scar treatment is required in future studies to determine whether it would result in a significant therapeutic outcome." | 3.30 | Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study. ( Disphanurat, W; Leelawattanachai, J; Sivapornpan, N; Srisantithum, B, 2023) |
| "This study aimed to investigate the efficacy and safety of punch excision combined with intralesional steroid injection for keloid treatment." | 3.30 | The Clinical Efficacy of Punch Excision Combined With Intralesional Steroid Injection for Keloid Treatment. ( Chen, Q; Chen, XD; Hou, S, 2023) |
| "Cryoanesthesia is ideally intended to cool only the epidermis during treatment and has advantage which did not require application time." | 3.30 | Cold anesthesia for pain reduction during intralesional steroid injection for nodulocystic acne. ( Kim, GH; Koh, YG; Park, KY; Park, SJ; Rho, NK; Shin, SH, 2023) |
| " Patient self-assessment, VAS scores, and adverse effects were also evaluated." | 3.11 | Efficacy and safety of thermomechanical fractional injury-assisted corticosteroid delivery versus intralesional corticosteroid injection for the treatment of hypertrophic scars: A randomized split-scar trial. ( Artzi, O; Gervasio, MKR; Manuskiatti, W; Wanitphakdeedecha, R; Yan, C, 2022) |
| " The safety assessment using VAS and adverse effects monitoring was completed." | 3.11 | Efficacy and safety of the innovative cold atmospheric-pressure plasma technology in the treatment of keloid: A randomized controlled trial. ( Nararatwanchai, T; Suwanchinda, A, 2022) |
| "Keloids are benign fibro-proliferative growths occurring after skin injury or spontaneously." | 3.11 | Combined intralesional triamcinolone acetonide and platelet rich plasma versus intralesional triamcinolone acetonide alone in treatment of keloids. ( Hegab, DS; Hewedy, ES; Mohamed, WS; Sabaa, BEI, 2022) |
| "Kynurenine shows promise as a topical treatment for keloids and hypertrophic scars." | 3.01 | A Randomized, Double-Blind, Active- and Placebo-Controlled Trial Evaluating a Novel Topical Treatment for Keloid Scars. ( Arnold, D; Berman, B; Fischer, DL; Gade, A; Han, H; Lawson, A; Nestor, MS, 2021) |
| "Long-pulsed Nd-YAG laser combined with intralesional bleomycin could be a promising way for treatment of keloids or hypertrophic scars." | 3.01 | The effectiveness of long Pulsed Nd:YAG Laser alone for treatment of keloids and hypertrophic scars versus its combination with bleomycin. ( Ramadan, H; Saber, M; Salah, M; Samy, N, 2021) |
| "Keloids are chronic progressive dermal pseudo-tumors that can grow considerably in volume and surface area but do not invade other tissues." | 3.01 | Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis. ( Charvet, E; Delaleu, J; Petit, A, 2023) |
| " Reported corticosteroid dosing that one would inject in one specific keloid differed by a factor of 40." | 3.01 | Intralesional corticosteroid administration in the treatment of keloids: a survey among Dutch dermatologists and plastic surgeons. ( Gibbs, S; Lapid, O; Louter, JMI; Niessen, FB; van Zuijlen, PPM; Wolkerstorfer, A; Yin, Q, 2023) |
| "Triamcinolone acetonide was used in 37 (97." | 3.01 | Intralesional Corticosteroid Administration in the Treatment of Keloids: A Scoping Review on Injection Methods. ( Gibbs, S; Lapid, O; Louter, JMI; Niessen, FB; Tasdemir-Kilic, G; van Zuijlen, PPM; Wolkerstorfer, A; Yin, Q, 2023) |
| "Keloids are defined as overrepairing products that develop after skin lesions." | 3.01 | Role of HIF-1α in pathogenic mechanisms of keloids. ( Li, ZJ; Long, X; Qiu, ZK; Si, LB; Wang, XJ; Yu, NZ; Zhang, MZ; Zhang, WC, 2023) |
| "Intralesional treatments for keloid and hypertrophic scars may be the most reliable treatment option to improve pathologic scars, while laser treatment may have specific benefits for Fitzpatrick skin types I-III over types IV-VI." | 3.01 | Treatment of traumatic hypertrophic scars and keloids: a systematic review of randomized control trials. ( Alam, M; Anvery, N; Asadbeigi, SN; Christensen, RE; Dirr, MA; Hisham, FI; Ibrahim, SA; Jain-Poster, K; Kang, BY; Kim, K; Merkel, EA; Poon, E; Reynolds, KA; Worley, B, 2023) |
| " No serious adverse reactions and good tolerability were reported in the included studies." | 3.01 | Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology-a systematic review. ( Bekkers, VZ; Bik, L; Prens, EP; van Doorn, MBA; van Huijstee, JC; Wolkerstorfer, A, 2023) |
| "Keloids are pathologic scars that pose a significant functional and cosmetic burden." | 3.01 | Keloid treatments: an evidence-based systematic review of recent advances. ( Kundu, RV; Kwan, KR; Miller, CH; Pontes, D; Poondru, S; Walsh, LA; Wu, E, 2023) |
| "Keloid is a type of disfiguring pathological scarring unique to human skin." | 3.01 | An updated review of the immunological mechanisms of keloid scars. ( Chen, CB; Chen, CH; Chung, WH; Lee, CC; Tsai, CH; Yeh, YC, 2023) |
| "Keloids and hypertrophic scars are the result of excessive fibroblast proliferation and collagen deposition in the wound healing process, leaving patients with irritating and cosmetically displeasing lesions." | 3.01 | Pediatric Keloids and Review of the Efficacy of Current Treatment Modalities. ( Haber, R; Hirsch, Y; Waterman, CL, 2023) |
| "Keloids are an exuberant response to skin wound healing in which abundant scar tissue grows beyond the boundaries of the inciting insult." | 3.01 | Keloids and Hypertrophic Scars. ( Glass, DA; Knowles, A, 2023) |
| " This review assesses recurrence and the reporting of recurrence in pathologic scar after treatment with intralesional triamcinolone (TAC) in combination with another intralesional agent." | 3.01 | Recurrence rates in the treatment of keloids and hypertrophic scars with intralesional triamcinolone combined with other intralesional agents. ( Chandy, RJ; Feldman, SR; Khan, D; Rimmer, SN, 2023) |
| "Keloids are a fibroproliferative skin disorder that develops in people of all ages." | 3.01 | Characterization of the skin keloid microenvironment. ( Chen, H; Qian, H; Wang, C; Zhang, M, 2023) |
| "Diseases such as uterine leiomyomata (fibroids and benign tumors of the uterus) and keloids (raised scars) may share common etiology." | 3.01 | Uterine leiomyomata and keloids fibrosis origins: a mini-review of fibroproliferative diseases. ( Edwards, TL; Hampton, G; Hellwege, JN; Kim, J; Velez Edwards, DR, 2023) |
| "Keloids are fibroproliferative disorders described by excessive growth of fibrotic tissue, which also invades adjacent areas (beyond the original wound borders)." | 3.01 | Modelling Keloids Dynamics: A Brief Review and New Mathematical Perspectives. ( Adebayo, OE; Bordas, SPA; Chouly, F; Eftimie, R; Rolin, G; Urcun, S, 2023) |
| "Keloids are a type of fibrotic disease characterized by excessive collagen production and extracellular matrix (ECM) deposition." | 3.01 | The Communication from Immune Cells to the Fibroblasts in Keloids: Implications for Immunotherapy. ( Li, D; Wu, X; Zhang, X, 2023) |
| "This prospective randomized study compared efficacy and tolerability as well as histological/immunohistochemical effects of liquid nitrogen contact cryosurgery as a single regimen (group A) and combined with intralesional corticosteroids (group B) on young (<2 years old), small (≤10 cm2) keloids in 40 patients (2-sided effect, α-error 1%, power 95%)." | 3.01 | Cryosurgery as a Single Agent and in Combination with Intralesional Corticosteroids Is Effective on Young, Small Keloids and Induces Characteristic Histological and Immunohistological Changes: A Prospective Randomized Trial. ( Zouboulis, CC; Zouridaki, E, 2021) |
| "Keloids are a type of disordered scar formation which not only show heterogeneity between individuals and within the scar itself, but also share common features of hyperproliferation, abnormal extra-cellular matrix deposition and degradation, as well as altered expression of the molecular markers of wound healing." | 3.01 | Differential responses to folic acid in an established keloid fibroblast cell line are mediated by JAK1/2 and STAT3. ( Alishahedani, ME; Freeman, AF; McCann, KJ; Myles, IA; Yadav, M, 2021) |
| "Stiffness in post-treated keloids and normal skins was significantly different (P < 0." | 2.94 | Quantitative assessment of treatment efficacy in keloids using high-frequency ultrasound and shear wave elastography: a preliminary study. ( Cheng, S; Guo, RQ; Huang, SY; Qiu, L; Wang, LY; Xiang, X, 2020) |
| "Keloids are a major complication related to surgical wound healing and very challenging condition to treat." | 2.94 | Histopathology and immunohistochemical analysis of 5-fluorouracil and triamcinolone treated keloids in double-blinded randomized controlled trial. ( Hietanen, KE; Huhtala, H; Järvinen, TAH; Kaartinen, IS; Tolonen, TT, 2020) |
| "Keloids and hypertrophic scars are challenging to both patients and physicians." | 2.94 | Evaluation of Fractional CO ( El-Tawdy, A; Foad, A; Metwally, D; Sayed, SS; Shaker, O; Shalaby, S; Tawfic, SO, 2020) |
| "Keloids are fibroproliferative skin disorders characterized by the progressive deposition of collagen." | 2.94 | Benefits of extracorporeal shock waves for keloid treatment: A pilot study. ( Choi, YS; Han, SH; Kim, DH; Suh, HS, 2020) |
| " Herein, we conducted a study to compare the efficacy of intralesional triamcinolone used alone, or in combination with BTA, in the treatment of formed keloid scars." | 2.90 | Intralesional triamcinolone alone or in combination with botulinium toxin A is ineffective for the treatment of formed keloid scar: A double blind controlled pilot study. ( Bakhshaeekia, A; Feily, A; Gianfaldoni, S; Hadibarhaghtalab, M; Lange, CS; Lotti, T; Matta, J; Pazyar, N; Ramirez-Fort, MK; Ramirez-Pacheco, LA; Rasaii, S; Seifi, V; Sohrabian, N, 2019) |
| "Keloids have high recurrence rates." | 2.90 | Treatment of keloid scars with intralesional triamcinolone and 5-fluorouracil injections - a randomized controlled trial. ( Hietanen, KE; Huhtala, H; Järvinen, TA; Kaartinen, IS; Kuokkanen, HO; Tolonen, TT, 2019) |
| "One of the first-line options to treat keloid scars is corticosteroid injection after excision of the existing scar." | 2.90 | Efficacy of surgical excision and sub-dermal injection of triamcinolone acetonide for treatment of keloid scars after caesarean section: a single blind randomised controlled trial protocol. ( Chua, SC; Gidaszewski, B; Khajehei, M, 2019) |
| "Keloid is characterized by benign overgrowth of dermal collagen in response to skin injury in genetically predisposed individuals." | 2.90 | Comparison of the efficacy of intralesional bleomycin versus intralesional triamcinolone acetonide in the treatment of keloids. ( Khan, HA; Paracha, MM; Sahibzada, MN, 2019) |
| "Keloids are a burden for patients due to physical, aesthetic and social consequences." | 2.87 | Intralesional cryotherapy versus excision with corticosteroid injections or brachytherapy for keloid treatment: Randomised controlled trials. ( Bijlard, E; Hovius, SER; Mureau, MAM; Niessen, FB; Timman, R; Verduijn, GM, 2018) |
| "After conventional treatments, keloid scars show varying degrees of recurrence." | 2.87 | Efficacy of Autologous Platelet Concentrates as Adjuvant Therapy to Surgical Excision in the Treatment of Keloid Scars Refractory to Conventional Treatments: A Pilot Prospective Study. ( Ezzedine, K; Hermeziu, O; Hersant, B; Meningaud, JP; Picard, F; Rodriguez, AM; SidAhmed-Mezi, M, 2018) |
| "Keloids have been one of the most concerning problems in cosmetic surgery." | 2.84 | Efficacy of Botulinum Toxin A in Preventing Recurrence Keloids: Double Blinded Randomized Controlled Trial Study: Intraindividual Subject. ( Burusapat, C; Pruksapong, C; Yingtaweesittikul, S, 2017) |
| "Keloids are the result of aberrant tissue scarring typically occurring in injured skin, and are caused by the overgrowth of granulation tissue or collagen type III during the healing process." | 2.82 | Novel targets and therapies for keloid. ( Naik, PP, 2022) |
| "Keloids are pathological wound healing responses to dermal injuries." | 2.82 | The Role of Interleukin 10 in Keloid Therapy: A Literature Review. ( Dilogo, IH; Harsono, AD; Prasetyono, TOH, 2022) |
| "Keloid and hypertrophic scars are the most common types of pathological scars." | 2.82 | Efficacy of the Neodymium-Doped Yttrium Aluminum Garnet Laser in the Treatment of Keloid and Hypertrophic Scars: A Systematic Review and Meta-analysis. ( Li, C; Pan, L; Qin, H; Yang, L; Zhang, G; Zhang, L, 2022) |
| "Keloids and hypertrophic scars are pathological cutaneous scars." | 2.82 | Role of Inflammasomes in Keloids and Hypertrophic Scars-Lessons Learned from Chronic Diabetic Wounds and Skin Fibrosis. ( Huang, C; Ogawa, R, 2022) |
| "Keloids are pathological scars extending beyond the initial wound's natural borders." | 2.82 | [Prevention and treatment of keloids]. ( Andersen, PS; Schønfeldt, T, 2022) |
| "Different approaches are used aiming to improve these scars, including intralesional corticosteroids, surgery and more recently, laser therapy." | 2.82 | Laser therapy for treating hypertrophic and keloid scars. ( da Silva, CA; da Silva, EM; Kuczynski, U; Leszczynski, R; Pinto, ACPN, 2022) |
| "PDL and long-pulsed Nd:YAG laser treatments for keloid and hypertrophic scar provide significant improvement with insignificant difference between both modalities." | 2.82 | Pulsed dye laser versus long-pulsed Nd:YAG laser in the treatment of hypertrophic scars and keloid: A comparative randomized split-scar trial. ( Al-Mohamady, Ael-S; Ibrahim, SM; Muhammad, MM, 2016) |
| "Keloids are common abnormally raised fibroproliferative lesions that can occur following even minor cutaneous trauma." | 2.80 | Clinical and epidemiological analysis of keloids in Chinese patients. ( Lu, WS; Yao, XH; Zhang, LF; Zheng, XD, 2015) |
| "Intralesional cryotherapy is a novel treatment for keloid scars in which the scar is frozen from inside." | 2.80 | Intralesional cryotherapy for treatment of keloid scars: a prospective study. ( Bulstra, AJ; Galindo-Garre, F; Molier, J; Niessen, FB; van der Wal, MBA; van Leeuwen, MCE; van Leeuwen, PAM; van Zuijlen, PPM, 2015) |
| " Severe adverse effects were not observed." | 2.79 | Adjuvant single-fraction radiotherapy is safe and effective for intractable keloids. ( Chang, H; Ha, SW; Kim, IH; Song, C; Wu, HG, 2014) |
| " At their institution, the authors have been treating keloids with a high-dose-rate brachytherapy procedure for over 10 years, using a protocol with the lowest total radiation dosage known in the literature." | 2.79 | High-dose-rate brachytherapy for the treatment of recalcitrant keloids: a unique, effective treatment protocol. ( Bulstra, AJ; Meijer, OWM; Niessen, FB; Stokmans, SC; van Leeuwen, MCE; van Leeuwen, PAM, 2014) |
| "Keloids and hypertrophic scars are the result of abnormal healing responses and dermal tissue proliferation; current surgical procedures can give rise to exuberant scarring and permanent functional loss or disfigurement." | 2.78 | Treatment of keloids and hypertrophic scars with bleomycin and electroporation. ( Cadossi, M; de Terlizzi, F; Gregorelli, C; Manca, G; Pandolfi, P, 2013) |
| "Keloids are a burden for patients due to physical, aesthetic and social complaints and treatment remains a challenge because of therapy resistance and high recurrence rates." | 2.78 | Intralesional cryotherapy versus excision and corticosteroids or brachytherapy for keloid treatment: study protocol for a randomised controlled trial. ( Bijlard, E; Busschbach, JJ; Mureau, MA; Niessen, FB; Timman, R; van Neck, JW; Verduijn, GM, 2013) |
| "Keloid was not statistically significant diferent in both groups (p = 0." | 2.78 | A prospective placebo-controlled study on the efficacy of onion extract in silicone derivative gel for the prevention of hypertrophic scar and keloid in median sternotomy wound in pediatric patients. ( Chatpreodprai, S; Lertsapcharoen, P; Peongsujarit, D; Wananukul, S, 2013) |
| "Intralesional cryosurgery effectively treats hypertrophic scars and keloids (HSK), but pain experienced by the patient during treatment can limit the application of cryosurgery." | 2.77 | Pain evaluation and control during and following the treatment of hypertrophic scars and keloids by contact and intralesional cryosurgery--a preliminary study. ( Gil, T; Goldin, I; Har-Shai, Y; Lavi, I; Mettanes, I; Mirmovich, O, 2012) |
| "Pulsed dye laser treatment of keloids significantly down-regulates the expression of CTGF in most cases." | 2.77 | The effect of flashlamp pulsed dye laser on the expression of connective tissue growth factor in keloids. ( Avram, MM; Guan, M; Huang, G; Lu, Z; Ma, Y; Yang, Q; Zhu, R, 2012) |
| "Keloids are aesthetically disfiguring and severely disabling." | 2.76 | Effects of combined intralesional 5-Fluorouracil and topical silicone in prevention of keloids: a double blind randomized clinical trial study. ( Ghafarian Shirazi, HR; Hatamipour, E; Hatamipour, M; Mehrabi, S, 2011) |
| "The remaining scar section was designated as control (no treatment)." | 2.75 | Comparison of the effects of short- and long-pulse durations when using a 585-nm pulsed dye laser in the treatment of new surgical scars. ( Caperton, C; Elgart, G; Elsaie, ML; Nouri, K; Patel, SS; Stevens, M; Vejjabhinanta, V, 2010) |
| "Ten points per scar were irradiated." | 2.75 | Effects of low-level laser therapy on pain and scar formation after inguinal herniation surgery: a randomized controlled single-blind study. ( Alcântara, PS; Carvalho, RL; Casarotto, RA; Cressoni, MD; Kamamoto, F, 2010) |
| "In both treatment groups, keloids responded well without any major side effect." | 2.75 | Surgical excision and immediate postoperative radiotherapy versus cryotherapy and intralesional steroids in the management of keloids: a prospective clinical trial. ( Dastgheib, L; Emad, M; Ghaem, H; Mortazavi, A; Omidvari, S, 2010) |
| "Keloids and hypertrophic scars are benign growths of dermal collagen that can cause physical and psychological (cosmetic) problems for patients." | 2.74 | Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2009) |
| "Keloids are distinguished by substantial deposition of collagen in the dermis, resulting in an imbalanced production and aggregation of extra cellular matrix." | 2.74 | Effect of camptothecin on collagen synthesis in fibroblasts from patients with keloid. ( Gao, WY; Guo, SZ; Han, Y; Li, X; Li, Y; Lu, KH; Ma, XJ; Xiao, B; Yan, L; Yi, CG; Zhang, GY; Zheng, Y, 2009) |
| "No reports of keloid formation, hypertrophic scarring, hypo- or hyperpigmentation, or other clinically significant adverse events were recorded." | 2.74 | Six-month safety results of calcium hydroxylapatite for treatment of nasolabial folds in Fitzpatrick skin types IV to VI. ( Boyd, CM; Grimes, PE; Marmur, ES; Porter, JP; Taylor, SC; Yoo, JY, 2009) |
| "A 595-nm PDL was safe and effective in treatment of hypertrophic scars and keloids in dark-skinned individuals." | 2.73 | Effect of pulse width of a 595-nm flashlamp-pumped pulsed dye laser on the treatment response of keloidal and hypertrophic sternotomy scars. ( Fitzpatrick, RE; Manuskiatti, W; Wanitphakdeedecha, R, 2007) |
| "Keloids are well-defined fibrous tissue overgrowths extending beyond the original defects." | 2.73 | Role of liquid nitrogen alone compared with combination of liquid nitrogen and intralesional triamcinolone acetonide in treatment of small keloids. ( Bhanot, A; Dewan, SP; Kaur, A; Sharma, S, 2007) |
| "Pruritus was relieved completely in 40 patients (88." | 2.73 | Treatment of keloids and hypertrophic scars using bleom. ( Aggarwal, H; Jain, DK; Lubana, PS; Mathur, RK; Saxena, A, 2008) |
| "Keloids are scars that extend beyond the margins of an insulting cutaneous injury." | 2.72 | Pruritus in Keloid Scars: Mechanisms and Treatments. ( Hawash, AA; Ingrasci, G; Nouri, K; Yosipovitch, G, 2021) |
| "Coupled with few effective treatments in keloid at present, we have focused on the immunological mechanisms of keloids with an aim to unravel some new therapeutic approaches in the future." | 2.72 | Emerging insights into the immunological aspects of keloids. ( Fu, S; Ogawa, R; Wu, H; Yu, Y; Zhang, Q, 2021) |
| "There are numerous strategies to treat keloid." | 2.72 | Drug delivery to optimize angiogenesis imbalance in keloid: A review. ( Kamalasanan, K; Kumar, AS, 2021) |
| "Chest keloids are a difficult sub-group of scars to treat, likely secondary to the high wound tension in the area that promotes excessive fibroblast proliferation and collagen deposition." | 2.72 | Chest keloids: effect of surgical excision and adjuvant radiotherapy on recurrence, a systematic review and meta-analysis. ( Fua, T; Miles, OJ; Paleri, S; Ramakrishnan, A; Zhou, J, 2021) |
| "Keloids are abnormal fibroproliferative scars with aggressive dermal growth expanding beyond the borders of the original injury." | 2.72 | Emerging and Novel Therapies for Keloids: A compendious review. ( Memariani, H; Memariani, M; Moravvej, H; Shahidi-Dadras, M, 2021) |
| " Intralesional corticosteroid injection alone and corticosteroid combined with botulinum toxin type A has been gradually found to be useful for the treatment of keloid and hypertrophic scars, but the difference in efficacy between the two is controversial." | 2.72 | Evaluation of Efficacy of Corticosteroid and Corticosteroid Combined with Botulinum Toxin Type A in the Treatment of Keloid and Hypertrophic Scars: A Meta-Analysis. ( Liu, XG; Zhang, D, 2021) |
| "Keloids and hypertrophic scars are harmful to physical and psychological health." | 2.72 | Comparative efficacy and safety of verapamil and triamcinolone in keloid and hypertrophic scar treatment: a meta-analysis. ( An, P; Kuang, J; Li, W, 2021) |
| "Keloids are a benign fibroproliferative disease with a high tendency of recurrence." | 2.72 | Adjuvant Radiotherapy after Surgical Excision in Keloids. ( Lee, JW; Seol, KH, 2021) |
| "Keloids are exuberant, disfiguring scars that result from an abnormal healing process." | 2.72 | Ineffective treatment of keloids with interferon alpha-2b. ( Al-Attar, A; Davison, SP; Kauffman, LC; Mess, S, 2006) |
| "Keloids and hypertrophic scars are benign growths of dermal collagen that usually cause major physical, psychological, and cosmetic problems." | 2.72 | New combination of triamcinolone, 5-Fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2006) |
| "HDR brachytherapy is an effective treatment for keloid scars." | 2.70 | Treatment of keloids by high-dose-rate brachytherapy: A seven-year study. ( Andrés, A; Finestres, F; Guix, B; Henríquez, I; Martínez, A; Tello, JI, 2001) |
| "Silicone gel dressings decrease scar volume and soften hypertrophic tissue, allowing it to be more easily controlled by other methods." | 2.70 | Silicone versus nonsilicone gel dressings: a controlled trial. ( Cintra, ML; de Oliveira, GV; Kitten, GT; Magna, LA; Nunes, TA; Raposo Do Amaral, CM; Zarpellon, S, 2001) |
| " Cryosurgery and intralesional corticosteroids have been considered as the mainstream of therapy; however, the long-term use of corticosteroids has been found to be associated with serious side effects." | 2.70 | Efficacy and safety of intralesional 5-fluorouracil in the treatment of keloids. ( Gupta, S; Kalra, A, 2002) |
| "No keloids were seen." | 2.69 | The use of silicone occlusive sheeting (Sil-K) and silicone occlusive gel (Epiderm) in the prevention of hypertrophic scar formation. ( Fidler, V; Kon, M; Niessen, FB; Robinson, PH; Spauwen, PH, 1998) |
| "Hypertrophic scars and keloids may complicate wound healing secondary to trauma or surgery." | 2.69 | Treatment of inflamed hypertrophic scars using intralesional 5-FU. ( Fitzpatrick, RE, 1999) |
| "Keloids are an abnormal response to wound healing distinguished by an overproduction of collagen." | 2.68 | Keloid excision and recurrence prophylaxis via intradermal interferon-gamma injections: a pilot study. ( Amsberry, J; Broker, BJ; Keane, WM; Pribitkin, EA; Rosen, D; Sailor, L; Schmidt, R, 1996) |
| "Keloids were measured and photographed before beginning therapy and weekly thereafter." | 2.67 | A controlled trial of intralesional recombinant interferon-gamma in the treatment of keloidal scarring. Clinical and histologic findings. ( Amento, EP; Flotte, TJ; Gallo, RL; Granstein, RD; Haas, A; Jaffe, HS; Rook, A, 1990) |
| "Meta-analysis revealed a recurrence rate of 39% (95% CI = 8." | 2.66 | Imiquimod to prevent keloid recurrence postexcision: A systematic review and meta-analysis. ( Aromataris, EC; Greenwood, JE; Klotz, T; Munn, Z, 2020) |
| " The outcome indicators were the numbers of patients with good-to-excellent effect, Vancouver Scar Scale (VSS) and adverse events." | 2.66 | Comparative Efficacy and Safety of Common Therapies in Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis. ( Bao, Y; Deng, J; Li, X; Pan, F; Pan, Z; Xu, S, 2020) |
| "Keloids are benign fibroproliferative dermal scars of unknown etiopathogenesis resulting in an exophytic protuberant growth with persistent and progressive peri-lesional expansile behavior." | 2.66 | Keloid scarring or disease: Unresolved quasi-neoplastic tendencies in the human skin. ( Bayat, A; Ud-Din, S, 2020) |
| "Keloid and hypertrophic scar formation after orthopaedic surgical closure is a complex issue." | 2.66 | Keloid and Hypertrophic Scar Formation, Prevention, and Management: Standard Review of Abnormal Scarring in Orthopaedic Surgery. ( Chen, E; Grabowski, G; Pacana, MJ, 2020) |
| "Keloidal morphea is a rare variant of scleroderma, which often can be clinically confused with keloid or scar formation." | 2.66 | Morphea With Keloidal Features: A Case Report and Review of the Literature. ( Ahn, C; Akkurt, ZM; Ibarra, BS; Sangüeza, OP; Yu, D, 2020) |
| "To compare recurrence rates for keloids treated with surgery plus one adjuvant intervention (dual therapy) versus surgery plus 2 or more adjuvant interventions (triple therapy)." | 2.66 | The Efficacy of Surgical Excision Plus Adjuvant Multimodal Therapies in the Treatment of Keloids: A Systematic Review and Meta-Analysis. ( Ellis, MM; Jones, LR; Ozog, DM; Siddiqui, F; Sunkara, PR, 2020) |
| " Although triamcinolone acetonide (TAC) is one of the most common and effective treatments for keloids and hypertrophic scars, TAC is not effective in some patients, and some may even experience adverse outcomes." | 2.66 | Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Deng, Z; Liu, L; Liu, R; Yang, B; Zhao, X, 2020) |
| "Hypertrophic scars are among the most common and frustrating problems after injury." | 2.66 | Nonsurgical Management of Hypertrophic Scars: Evidence-Based Therapies, Standard Practices, and Emerging Methods. ( Atiyeh, BS, 2020) |
| "Keloids and hypertrophic scars are pathological scars that result from aberrant wound healing." | 2.66 | The Roles of Inflammation in Keloid and Hypertrophic Scars. ( Cai, JQ; Cao, Y; Liu, YQ; Shen, XZ; Shi, P; Sun, Q; Tan, WQ; Wang, ZC; Zhao, WY, 2020) |
| "Abnormal scars, such as hypertrophic scars and keloids, and cutaneous fibrosis that develops in diseases such as systemic sclerosis and graft-versus-host disease can be even more challenging for patients." | 2.66 | A Review of the Evidence for and against a Role for Mast Cells in Cutaneous Scarring and Fibrosis. ( Bayat, A; Ud-Din, S; Wilgus, TA, 2020) |
| "There were recurrences in both groups." | 2.66 | Carbon dioxide laser excision of earlobe keloids. A prospective study and critical analysis of existing data. ( Lucente, FE; Stern, JC, 1989) |
| "Keloids are considered as benign fibroproliferative skin tumors growing beyond the site of the original dermal injury." | 2.61 | Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies. ( Bayat, A; Khumalo, N; Tan, S, 2019) |
| "Keloids have been assessed by numerous methods and severity indices resulting in a lack of standardization across published research." | 2.61 | Disease Severity and Quality of Life Outcome Measurements in Patients With Keloids: A Systematic Review. ( Braunberger, TL; Lyons, AB; Ozog, DM; Peacock, A; Viola, KV, 2019) |
| "Climate change may result in spreading lobomycosis to currently disease-free areas of the world." | 2.61 | An atypical keloid in a Brazilian man. ( Blaizot, R; Blanchet, D; Chanlin, R; Couppie, P; Demar, M; Garcia, M, 2019) |
| "Keloids are exuberant responses to cutaneous wound healing." | 2.61 | Patient-reported outcomes for keloids: a systematic review. ( Glass, DA; Tan, A, 2019) |
| "A keloid is a type of unusually raised scar." | 2.61 | Advances in diagnostic methods for keloids and biomarker-targeted fluorescent probes. ( Hur, JK; Kang, S; Kim, D, 2019) |
| "The aetiology of keloids is becoming clearer, but many questions remain, including about the most optimal treatment." | 2.61 | Managing keloid scars: From radiation therapy to actual and potential drug deliveries. ( Du, Y; Huang, C; Liu, L; Ogawa, R; You, Z, 2019) |
| "Cellular mechanisms of scarring and possible ways for its prevention are highlighted." | 2.61 | Regeneration of Dermis: Scarring and Cells Involved. ( Kalabusheva, EP; Rippa, AL; Vorotelyak, EA, 2019) |
| "Keloids and hypertrophic scars are often associated with itching, pain, tautness of the skin, and functional impairments, thus, leading to significantly reduced quality of life in some patients." | 2.58 | [Therapy of scars with lasers]. ( Clementoni, MT; Gauglitz, GG; Pötschke, J, 2018) |
| "Keloids and hypertrophic scars are conditions of pathologic scarring characterized by fibroblast hyperproliferation and excess collagen deposition." | 2.58 | The Cellular Response of Keloids and Hypertrophic Scars to Botulinum Toxin A: A Comprehensive Literature Review. ( Austin, E; Jagdeo, J; Koo, E, 2018) |
| "Previous treatments for keloids include surgery, drugs, lasers and so on." | 2.58 | [Advances in the research of drug intralesional injection therapy in keloid]. ( Guo, QG; Yao, M, 2018) |
| "Keloids are benign fibroproliferative tumors that extend beyond the original wound." | 2.58 | Spontaneous Keloids: A Literature Review. ( Alajmi, A; Jfri, A, 2018) |
| "Keloids and hypertrophic scars are fibroproliferative disorders of dermal tissue after skin injury." | 2.55 | Review of Silicone Gel Sheeting and Silicone Gel for the Prevention of Hypertrophic Scars and Keloids. ( Hsu, KC; Luan, CW; Tsai, YW, 2017) |
| "Skin fibrosis is a common pathological process characterized by fibroblast proliferation and excessive deposition of extracellular matrix." | 2.55 | MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment. ( Chen, T; Lei, Y; Li, Y; Lyu, L; Zhang, J; Zuo, R, 2017) |
| "Keloids are an exuberant response to cutaneous wound healing." | 2.55 | Current Understanding of the Genetic Causes of Keloid Formation. ( Glass, DA, 2017) |
| "Therefore, tailor made manipulation of cancer stroma can have important therapeutic consequences." | 2.55 | How Signaling Molecules Regulate Tumor Microenvironment: Parallels to Wound Repair. ( Fáber, L; Gál, P; Mirossay, A; Mitrengová, P; Mučaji, P; Novák, Š; Smetana, K; Szabo, P; Varinská, L, 2017) |
| " We aimed to compare the efficacy and safety of TAC alone and in combination with 5-FU for the treatment of hypertrophic scars and keloids." | 2.55 | Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis. ( Fan, B; Feng, S; Lin, W; Ren, Y; Wei, Z; Zhou, X, 2017) |
| "Fibrosis is a common pathological state characterized by the excessive accumulation of extracellular matrix components, but the pathogenesis of the disease is still not clear." | 2.55 | MicroRNA-29: A Crucial Player in Fibrotic Disease. ( Deng, Z; He, L; He, Y; Lu, L; Shi, A; Shi, H; Yang, X, 2017) |
| "The high recurrence rate of keloids has lead to the use of multiple treatment adjuncts to improve cosmetic outcomes after surgery." | 2.55 | Optimizing Radiotherapy for Keloids: A Meta-Analysis Systematic Review Comparing Recurrence Rates Between Different Radiation Modalities. ( Dyachenko, A; Kanevsky, J; Luc, M; Mankowski, P; Tomlinson, J, 2017) |
| "Keloids and hypertrophic scars are caused by cutaneous injury and irritation, including trauma, insect bite, burn, surgery, vaccination, skin piercing, acne, folliculitis, chicken pox, and herpes zoster infection." | 2.55 | Keloid and Hypertrophic Scars Are the Result of Chronic Inflammation in the Reticular Dermis. ( Ogawa, R, 2017) |
| "Random individual scarring may be minimized by a dynamic personalized accompanying scarring." | 2.53 | [How to optimize scarring in dermatologic surgery?] ( Amici, JM; Chaussade, V, 2016) |
| "The etiology of keloids is unknown but they occur after dermal injury in genetically susceptible individuals, and they cause both physical and psychological distress for the affected individuals." | 2.53 | Keloids: The paradigm of skin fibrosis - Pathomechanisms and treatment. ( Andrews, JP; Macarak, E; Marttala, J; Rosenbloom, J; Uitto, J, 2016) |
| "Acne scarring can be classified into atrophic icepick, boxcar, and rolling scars in addition to keloidal and hypertrophic scars." | 2.53 | Acne Scar Treatment: A Multimodality Approach Tailored to Scar Type. ( Fabi, SG; McGraw, T; Taylor, M; Zaleski-Larsen, LA, 2016) |
| "A stepwise algorithm for the treatment of hypertrophic scars or keloids based on the characteristics and responsiveness of the scar presents the best management strategy." | 2.53 | Advances in scar management: prevention and management of hypertrophic scars and keloids. ( Dedhia, R; Del Toro, D; Tollefson, TT, 2016) |
| "Keloids and hypertrophic scars are fibroproliferative disorders of the skin that are caused by abnormal healing of injured or irritated skin." | 2.53 | Keloids and Hypertrophic Scars Can Now Be Cured Completely: Recent Progress in Our Understanding of the Pathogenesis of Keloids and Hypertrophic Scars and the Most Promising Current Therapeutic Strategy. ( Akaishi, S; Kuribayashi, S; Miyashita, T; Ogawa, R, 2016) |
| "Pathological skin scars, such as keloids, aesthetically and psychosocially affect patients." | 2.53 | Will stem cells bring hope to pathological skin scar treatment? ( Fu, X; Li, Q; Zhang, C, 2016) |
| "Auricularis keloids are the keloids locating on the earlobe and helix which often caused by ear piercing, burn wound and skin injury." | 2.53 | [Advances in therapy of auricular keloid]. ( Liu, K; Wang, PH; Wu, XL, 2016) |
| "Keloid is an excessive dermal scar occurring in response to skin injuries." | 2.52 | Molecular signalings in keloid disease and current therapeutic approaches from natural based compounds. ( Chanvorachote, P; Nimmannit, U; Pongrakhananon, V; Sucontphunt, A; Unahabhokha, T; Yongsanguanchai, N, 2015) |
| "Many different algorithms for scar prophylaxis and treatment have been presented in the literature." | 2.52 | [Scar prophylaxis and treatment]. ( Damsgaard, TE; Hammer-Hansen, N; Rødgaard, JC, 2015) |
| "Keloids are defined as benign dermal scars invading adjacent healthy tissue, characterized by aberrant fibroblast dynamics and overproduction of extracellular matrix." | 2.52 | microRNA deregulation in keloids: an opportunity for clinical intervention? ( Chan, MT; Li, Z; Wu, WK; Yu, X, 2015) |
| "To provide a comprehensive evidence-based review of current evidence on mechanism of action, efficacy, and adverse events of calcium antagonists in treatment of hypertrophic scars and keloids." | 2.52 | Mechanism of Action, Efficacy, and Adverse Events of Calcium Antagonists in Hypertrophic Scars and Keloids: A Systematic Review. ( Piatkowski de Grzymala, A; van der Hulst, R; Verhiel, S, 2015) |
| "Keloids are an overgrowth of fibrotic tissue outside the original boundaries of an injury and occur secondary to defective wound healing." | 2.50 | Laser and light-based treatment of Keloids--a review. ( Jagdeo, JR; Lev-Tov, H; Mamalis, AD; Nguyen, DH, 2014) |
| "Keloids and hypertrophic scars are prevalent disabling conditions with still suboptimal treatments." | 2.50 | New molecular medicine-based scar management strategies. ( Arno, AI; Barret, JP; Gauglitz, GG; Jeschke, MG, 2014) |
| "Keloids are fibroproliferative extreme variants of an impaired wound healing, developing a tumour-like growth." | 2.50 | [Functional and aesthetic therapy concepts of keloids in the head- and neck area]. ( Brom, J; Freuschle, A; Hörmann, K; Schultz, JD, 2014) |
| "Management of incisional scar is intimately connected to stages of wound healing." | 2.50 | Overview of surgical scar prevention and management. ( Harijan, A; Son, D, 2014) |
| "Keloids are proliferative fibrous growths resulting from excessive tissue response to skin trauma." | 2.50 | Keloids in Rubinstein-Taybi syndrome: a clinical study. ( de Jong, D; Hennekam, RC; Houge, G; Peters, DJ; Shaw, AC; van Belzen, MJ; van de Kar, AL, 2014) |
| "Keloids are common cutaneous pathological scars that are characterised by the histological accumulation of fibroblasts, collagen fibres, and clinically significant invasive growth." | 2.49 | Roles of lipid metabolism in keloid development. ( Huang, C; Ogawa, R, 2013) |
| "At present, to treat or prevent keloids, new drugs are currently being designed and the pharmaceutical indications of known drugs are being expanded." | 2.49 | Pharmacological treatment for keloids. ( Huang, C; Ogawa, R, 2013) |
| "Keloid and hypertrophic scars are common and are caused by a proliferation of dermal tissue following skin injury." | 2.49 | Silicone gel sheeting for preventing and treating hypertrophic and keloid scars. ( Jones, DJ; O'Brien, L, 2013) |
| "Keloid is a disease that is difficult to cure because of its high recurrence rate after chemotherapy or radiotherapy, therefore it is considered as a benign skin tumor." | 2.49 | Pathological niche environment transforms dermal stem cells to keloid stem cells: a hypothesis of keloid formation and development. ( Chai, G; Liu, W; Qu, M; Song, N; Wu, X, 2013) |
| "Keloid is a kind of pathological scar of skin, which would seriously impair patient's quality of life." | 2.49 | [Advances in the research of the effect of toll-like receptor in the formation of keloid]. ( Wang, HM; Xu, JH; Xu, X, 2013) |
| "The medical subject headings ''scarring'' were combined with ''mechanisms''." | 2.48 | An overview of biological basis of pathologic scarring. ( Adeyemo, WL; Mofikoya, BO; Ugburo, AO, 2012) |
| "A keloid scar is a benign proliferative lesion of dermic collagen." | 2.48 | [Keloid scars of the head and neck]. ( Beogo, R; Guiébré, YM; Ouoba, K; Sérémé, M; Zwetyenga, N, 2012) |
| "Although there is evidence suggesting genetic susceptibility for keloids, studies investigating the association between Arg72Pro polymorphism in the P53 gene and tendency to form keloids have given variable results." | 2.48 | Meta-analysis demonstrates association between Arg72Pro polymorphism in the P53 gene and susceptibility to keloids in the Chinese population. ( Chen, HD; Chen, JZ; Gao, XH; Li, YH; Luo, YJ; Wang, B; Wei, HC; Wu, Y; Xu, XG, 2012) |
| "Over the past two decades the treatment of hypertrophic scars and keloids has seen substantial changes due to the evolution of current and establishment of new conservative and surgical methods." | 2.48 | [Keloid and hypertrophic scar treatment modalities. An update]. ( Branski, LK; Rennekampff, HO; Vogt, PM, 2012) |
| "Fibrosis is initiated by a variety of pathological, physiological, biochemical, and physical factors." | 2.48 | Organ fibrosis inhibited by blocking transforming growth factor-β signaling via peroxisome proliferator-activated receptor γ agonists. ( Cheng, NS; Deng, YL; Xiong, XZ, 2012) |
| "Keloids and hypertrophic scars affect millions of patients." | 2.48 | Pulsed dye laser for the treatment of keloid and hypertrophic scars: a systematic review. ( de las Alas, JM; Dofitas, BL; Siripunvarapon, AH, 2012) |
| "Of course, the best treatment for keloids remains prevention." | 2.47 | Advances in the treatment of keloids. ( Berman, B; Caperton, CV; Viera, MH, 2011) |
| "Large and multiple keloids are difficult to treat radically and are currently only treatable by multimodal therapies that aim to relieve symptoms." | 2.47 | Are there any good treatments for keloid scarring after sternotomy? ( Cummings, I; Pai, VB, 2011) |
| "New approaches to wound/scar therapy are discussed." | 2.47 | Mechanisms of pathological scarring: role of myofibroblasts and current developments. ( Billet, F; Coulomb, B; Desmoulière, A; Micallef, L; Sarrazy, V, 2011) |
| "There is strong evidence suggesting a genetic susceptibility in individuals affected by KD, including familial heritability, common occurrence in twins and high prevalence in certain ethnic populations." | 2.46 | Genetics of keloid scarring. ( Bayat, A; Shih, B, 2010) |
| "Though both forms of pathologic scarring are distinct entities at the macro and microscopic level, their etiologies and treatment are often similar." | 2.46 | The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review. ( Basdag, B; Magarakis, M; Manson, PN; Rosson, GD; Shridharani, SM; Singh, NK, 2010) |
| "Acne scarring is common but difficult to treat." | 2.46 | [Therapy of acne scars]. ( Jansen, T; Podda, M, 2010) |
| "Keloids are the result of a dysfunctional scarring process that leads to excessive deposition of extracellular matrix in susceptible individuals, causing them physical, psychological, and social discomfort." | 2.46 | Keloids: a new challenge for nutrition. ( Bonatti, S; Ferreira, AC; Ferreira, LM; Furtado, F; Hochman, B, 2010) |
| "Once pseudofolliculitis has become established, treatment consists of avoiding shaving and the use of medical treatment similar to that used in acne." | 2.46 | [Pseudofolliculitis barbae]. ( Casals, M; Fernández-Chico, N; Ribera, M, 2010) |
| "Keloids are a common presenting complaint in the primary care clinic." | 2.45 | A primary care perspective on keloids. ( Aziz, N; Davidson, S; Khachemoune, A; Rashid, RM, 2009) |
| "While, fetal wounds heal without scarring, a normal "fine line" scar is the clinical outcome of an undisturbed wound healing in adults." | 2.45 | Keloid scarring: bench and bedside. ( Mrowietz, U; Seifert, O, 2009) |
| "To show radiation dose-response relationships for recurrence of keloid and pterygium after radiotherapy following surgery." | 2.45 | Dose-effect relationships for recurrence of keloid and pterygium after surgery and radiotherapy. ( Jürgenliemk-Schulz, IM; Kal, HB; Veen, RE, 2009) |
| "Keloid and hypertrophic scars are multifaceted aberrations of the healing process with as yet incompletely understood aetiologies." | 2.45 | Genetic susceptibility to raised dermal scarring. ( Bayat, A; Brown, JJ, 2009) |
| "Keloids are scars, unique to humans, that grow beyond the boundaries of a cutaneous injury, inflammation, burn, or surgical incision." | 2.45 | Update on the management of keloids. ( Kelly, AP, 2009) |
| "Excess scar formation occurs after dermal injury as a result of abnormal wound healing." | 2.45 | Keloids: current concepts of pathogenesis (review). ( Bran, GM; Goessler, UR; Hormann, K; Riedel, F; Sadick, H, 2009) |
| "Keloids are benign fibroproliferative tumors but often cause serious cosmetic problems." | 2.45 | [Keloids: pathogenic and therapeutic advances]. ( Adam, S; Lari, N; Morand, JJ; Salles, F; Thiéry, G, 2009) |
| "Keloids have been treated by using radiation for over a century, and it is currently suggested that keloids are best treated by a combination of surgery and postoperative radiation therapy, although randomized controlled trials testing this are still lacking." | 2.45 | Is radiation therapy for keloids acceptable? The risk of radiation-induced carcinogenesis. ( Miyashita, T; Ogawa, R; Yoshida, K; Yoshitatsu, S, 2009) |
| "Reports of corneal keloids are rare, with fewer than 80 cases published since the first case was documented in 1865." | 2.44 | Corneal keloid. ( Kai, S; Panda, A; Sen, S; Vanathi, M, 2008) |
| "For centuries, keloids have been an enigma and despite considerable research to unravel this phenomenon no universally accepted treatment protocol currently exists." | 2.44 | The keloid phenomenon: progress toward a solution. ( Louw, L, 2007) |
| "Lasers have been used in the treatment of hypertrophic scars and keloids for more than 20 years." | 2.44 | Laser treatment of keloids and hypertrophic scars. ( Bouzari, N; Davis, SC; Nouri, K, 2007) |
| "Keloids are abnormal wound reactions of connective tissue." | 2.44 | Therapy of auricular keloids: review of different treatment modalities and proposal for a therapeutic algorithm. ( Froelich, K; Hagen, R; Kleinsasser, N; Staudenmaier, R, 2007) |
| "The basic treatment of keloids changed, radiotherapy was combined with the above mentioned methods because of its high recurrence rate." | 2.44 | [Current methods of treatment and prevention of pathologic scars]. ( Kelemen, O; Kollár, L, 2007) |
| "Keloids are benign fibroproliferative diseases of unknown aetiology." | 2.44 | Transforming growth factor beta (TGFbeta) and keloid disease. ( Bayat, A; Jagadeesan, J, 2007) |
| "Keloids are benign fibrous growths that appear after surgery, trauma or "spontaneously" as a consequence of microtrauma in predisposed patients." | 2.44 | [Therapy of keloids]. ( Karrer, S, 2007) |
| " The precise mechanism of action of silicone elastomer sheeting has not been defined, but clinical trials report that this device is safe and effective for the treatment and prevention of hypertrophic and keloid scars if worn over the scar for 12 to 24 hours per day for at least 2 to 3 months." | 2.44 | A review of the biologic effects, clinical efficacy, and safety of silicone elastomer sheeting for hypertrophic and keloid scar treatment and management. ( Berman, B; Delgado, S; Kohut, BE; Konda, S; Li, Q; Perez, OA; Viera, MH; Zell, D, 2007) |
| "Keloids and hypertrophic scars are different forms of excessive dermal fibrosis thought to be caused by regulation of cellularity increase and decrease during the wound-healing process in predisposed individuals." | 2.44 | Keloids and hypertrophic scars: are they two different sides of the same coin? ( Köse, O; Waseem, A, 2008) |
| "Keloid and hypertrophic scars are 2 types of excessive scarring observed clinically that require different therapeutic approaches." | 2.43 | Keloid or hypertrophic scar: the controversy: review of the literature. ( Atiyeh, BS; Costagliola, M; Hayek, SN, 2005) |
| "To review the recurrence rates of keloids after surgical excision followed by radiotherapy, and to answer the question whether after normalization of the dose, a dose-effect relationship could be derived." | 2.43 | Biologically effective doses of postoperative radiotherapy in the prevention of keloids. Dose-effect relationship. ( Kal, HB; Veen, RE, 2005) |
| "Keloid and hypertrophic scars are common and are caused by a proliferation of dermal tissue following skin injury." | 2.43 | Silicon gel sheeting for preventing and treating hypertrophic and keloid scars. ( O'Brien, L; Pandit, A, 2006) |
| "Keloids are benign and occur secondary to an imbalance between the synthesis of extracellular matrix and its degradation." | 2.43 | [How I treat...fibroproliferative scars]. ( Deleuze, JP; Grandjean, FX; Heymans, O; Nickers, P; Schmitz, C; Smeets, L, 2006) |
| "Keloids are common benign tumors of the dermis, typically arising after insult to the skin." | 2.43 | Case report and summary of literature: giant perineal keloids treated with post-excisional radiotherapy. ( Childs, CC; Fuller, CD; Herman, TS; Jones, K; Luh, JY; Miller, AR; Thomas, CR; Tolcher, AW, 2006) |
| "Keloid and hypertrophic scars are the result of abnormal processes in scar formation." | 2.43 | Epidemiology, aetiology and management of abnormal scarring: a review of the literature. ( Pellard, S, 2006) |
| "Keloids are special type of skin lesions arising from sites of previous trauma." | 2.43 | [Therapeutic problems connected with keloid treatment--new treatment possibilities]. ( Brudnik, U; Podolec-Rubiś, M; Wojas-Pelc, A, 2006) |
| "Fibroproliferative scars remain an ongoing clinical challenge." | 2.42 | Fibroproliferative scars. ( Garner, WL; Rahban, SR, 2003) |
| "Keloids are benign fibrous growths with characteristic clinical features, whose underlying pathogenic mechanisms are not fully understood." | 2.42 | [The treatment of keloids]. ( Aschoff, R; Hackert, I; Sebastian, G, 2003) |
| "Keloids were thought to be prevalent in TS, but recent data suggest otherwise." | 2.42 | Turner's syndrome in dermatology. ( Glick, SA; Kim, KH; Lowenstein, EJ, 2004) |
| "Keloids are benign, but sometimes painful and/or pruritic, proliferative growths of dermal collagen, usually resulting from excessive tissue response to trauma." | 2.42 | Medical and surgical therapies for keloids. ( Kelly, AP, 2004) |
| "Earlobe keloids are commonly encountered in dermatological practice and often prove to be recurrent, despite a variety of treatment options." | 2.42 | Role of adjuvant radiotherapy in recurrent earlobe keloids. ( Dinh, Q; Richards, S; Veness, M, 2004) |
| "Keloids are defined as excessive scar tissue formation extending beyond the area of the original skin injury and occurring in predisposed individuals." | 2.42 | Keloids--clinical diagnosis, pathogenesis, and treatment options. ( Krieg, T; Marneros, AG, 2004) |
| "Successful treatment of keloids is difficult." | 2.41 | [Keloids. A fibroproliferative disorder of unknown etiology]. ( Bock, O; Mrowietz, U, 2002) |
| "A scar contracture is the result of a contractile wound-healing process occurring in a scar that has already been reepithelialized and adequately healed." | 2.41 | Scar contractures, hypertrophic scars, and keloids. ( Brissett, AE; Sherris, DA, 2001) |
| "Excess scarring caused by pathologically overabundant collagen deposition is a problem known by all surgeons." | 2.40 | Hypertrophic scars and keloids: a recurrent problem revisited. ( Ellitsgaard, N; Ellitsgaard, V, 1997) |
| "Vascular restenosis is currently one of the new frontiers of radiation therapy and offers opportunities to explore the role of inflammatory or immune cell responses in benign conditions that lead to excessive fibrogenesis and require treatment." | 2.40 | The molecular and cellular biologic basis for the radiation treatment of benign proliferative diseases. ( Rubin, P; Soni, A; Williams, JP, 1999) |
| "Although optimal treatment for keloids remains undefined, successful treatment can be obtained through a multimodality approach." | 2.40 | Keloids and hypertrophic scars. ( English, RS; Shenefelt, PD, 1999) |
| "The treatment of keloids has always been a formidable task and no definitive treatment method has yet been established." | 2.40 | [Keloids]. ( Arai, K, 1999) |
| "Earlobe keloids are a challenging management problem." | 2.39 | Earlobe keloids. ( DeWitt, DE; Zuber, TJ, 1994) |
| " Other elastin deficiencies may be due to excess elastolysis or gene dosage effects." | 2.39 | Regulation of elastin synthesis in pathological states. ( Davidson, JM; Giro, MG; Zang, MC; Zoia, O, 1995) |
| "A review of the surgical treatment of keloids with emphasis on surgery combined with nonsurgical therapies is presented." | 2.39 | Adjunct therapies to surgical management of keloids. ( Berman, B; Bieley, HC, 1996) |
| "Keloids and hypertrophic scars in children are effectively treated with silicone gel sheeting." | 2.39 | Skin disorders in black children. ( Laude, TA, 1996) |
| "There is no one right way to treat all keloids and hypertrophic scars." | 2.38 | Keloids and hypertrophic scars. ( Nemeth, AJ, 1993) |
| "Hypertrophic scars and keloids may be resolved through light topical pressure maintained over time." | 2.38 | The microvessels in hypertrophic scars, keloids and related lesions: a review. ( Kischer, CW, 1992) |
| "Keloids are a benign proliferative growth of dermal collagen usually resulting from an excessive tissue response to skin trauma in predisposed individuals." | 2.38 | Keloids. ( Doyle-Lloyd, DJ; White, JA, 1991) |
| "Keloids and hypertrophic scars may complicate elective foot surgery." | 2.38 | Management of keloids and hypertrophic scars. ( Kanat, IO; Tritto, M, 1991) |
| "The use of radiations for the treatment of keloids was the topic of debate for years." | 2.38 | Treatment of keloids by 90Sr-90Y beta-rays. ( Deka, AC; Deka, BC; Rao, SM; Supe, SJ; Supe, SS, 1991) |
| "Wound dehiscence, hypertrophic scars, and keloids are three complications that can prove to be a nighmore to any surgeon." | 2.38 | Complications of foot surgery. Wound dehiscence, hypertrophic scars, and keloids. ( Wilczynski, RJ, 1991) |
| "Keloid is a disease principally of the human dermis, and occasionally the cornea, appearing as thick scar tissue invading normal skin or cornea and produced by the deposition of excessive amounts of collagen over prolonged periods." | 2.38 | Keloids: a review of the literature. ( Datubo-Brown, DD, 1990) |
| "Patients with facial scars are vulnerable in a way that few others are, and it is the responsibility of the facial plastic surgeon to evaluate these patients properly and realistically, to prepare them for a process that may involve multiple procedures, and to see them through this process with all the expertise and compassion possible." | 2.38 | Scar revision and camouflage. ( Ehlert, TK; Thomas, JR, 1990) |
| "Keloids are benign fibrous growths that result from an abnormal connective tissue response in certain predisposed individuals." | 2.37 | Keloids. ( Kelly, AP, 1988) |
| " Definite dosage reductions can be achieved by suitable radioprotective measures." | 2.37 | [Radiation treatment of benign diseases--indications, results and technic]. ( Hassenstein, E, 1986) |
| "The use of several modalities for the treatment of acne scarring is advocated; these include dermabrasion, punch-transplant replacement techniques, and collagen implants." | 2.36 | Cosmetic dermatologic surgery. ( Stegman, SJ; Tromovitch, TA, 1982) |
| "Keloids are predominantly fibrous tumors which appear as firm, variably pruritic or tender growths near a site of injury." | 2.36 | Keloids: a review. ( Murray, JC; Pinnell, SR; Pollack, SV, 1981) |
| "Keloids are laterally growing fibroproliferative skin disorders." | 1.91 | Combination Therapy for a Severe Axillary Keloid with Abscesses: A Case Report. ( Cho, H; Dohi, T; Fukumitsu, K; Hayakawa, S; Kamegai, M; Karasawa, K; Ogawa, R; Shimizuguchi, T, 2023) |
| "Keloid is a common dermis tumor, occurring repeatedly, affecting the quality of patients' life." | 1.91 | LncRNA GNAS-AS1 knockdown inhibits keloid cells growth by mediating the miR-188-5p/RUNX2 axis. ( Gao, F; Li, L; Liang, ZH; Lin, SS; Lin, X; Liu, Y; Qiu, ZY; Wang, JY, 2023) |
| "Keloids are benign dermal tumors that arise from abnormal wound healing processes following skin lesions." | 1.91 | Molecular response of keloids to ionizing radiation: targeting FOXO1 radiosensitizes keloids. ( Chen, S; Hong, M; Li, X; Liu, Y; Mo, W; Shi, B; Shi, Y; Yan, T; Yu, D; Zhang, S, 2023) |
| "Keloids are pathological scars that invade normal surrounding tissue without self-limitation, causing pain, itching, cosmetic disfigurement, etc." | 1.91 | Invariant chain of the MAIT-TCR vα7.2-Jα33 as a novel diagnostic biomarker for keloids. ( Nurzat, Y; Xu, H; Zhang, Y; Zhu, Z, 2023) |
| "Treatment of chest keloids is challenging." | 1.91 | Early outcomes of complete excision followed by immediate postoperative single fractional 10 Gy for anterior chest keloids: A preliminary results. ( Ha, B; Im, S; Kim, SJ; Lee, YJ; Park, TH, 2023) |
| "Since keloids are driven by skin injuries, the existence of keloidal dermatofibroma has been suggested to support the injury hypothesis of dermatofibroma etiology." | 1.91 | Keloidal dermatofibroma: Clinicopathological comparison of 52 cases with a series of 2077 other dermatofibromas. ( Akaishi, S; Ansai, SI; Dohi, T; Nishimoto, A; Ogawa, R, 2023) |
| "A keloid is a benign fibroproliferative skin tumor whose formation is regulated by circular RNAs (circRNAs)." | 1.91 | hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940. ( Cai, M; Hu, Z; Liu, L; Su, J, 2023) |
| "The KAAS can predict recurrence in patients with chest keloids after surgery and radiotherapy." | 1.91 | A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy. ( Hao, Y; Liang, Z; Liu, H; Shan, M; Song, K; Wang, Y; Xia, Y, 2023) |
| "Keloid is a benign fibro-proliferative dermal tumour formed by an abnormal scarring response to injury and characterised by excessive collagen accumulation and invasive growth." | 1.91 | Bioinformatics analysis and identification of dysregulated POSTN in the pathogenesis of keloid. ( Hu, Z; Wang, Z; Xu, H; Yang, H; Zhu, J, 2023) |
| "A standardized and sequential treatment plan for keloids with different morphology and anatomical locations can achieve remodeling of the auricular morphology and maintain long-term results." | 1.91 | Contour first-retrospective study of an algorithmic approach of auricular keloids. ( Dong, G; Hu, J; Jin, Q; Liu, Y; Qu, C; Wang, L; Wang, M; Wu, H, 2023) |
| "The association with uterine leiomyoma was borderline significant in Black women (OR, 1." | 1.91 | Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank. ( Barker, JN; Dand, N; McGrath, JA; Onoufriadis, A; Parsons, M; Shaw, TJ; Ung, CY; Warwick, A, 2023) |
| "Standard treatment for keloids includes combination intralesional therapy with triamcinolone and fluorouracil." | 1.91 | Common Dermatologic Conditions in Skin of Color. ( Frazier, WT; Proddutur, S; Swope, K, 2023) |
| "The incidence of keloids is higher in the case of darker skin." | 1.91 | Cyclical Stretching Induces Excess Intracellular Ca2+ Influx in Human Keloid-Derived Fibroblasts In Vitro. ( Abe, Y; Hashimoto, I; Ishida, S; Minami, K; Mineda, K; Nakahara, T; Sato, K; Yamashita, Y, 2023) |
| "Keloid is a pathological dermatological condition that manifests as an overgrowth scar secondary to skin trauma." | 1.91 | Integration of single-cell and bulk transcriptomics reveals immune-related signatures in keloid. ( Qi, S; Tang, J; Wang, H; Xie, J; Zhou, Z, 2023) |
| "Keloids are considered the manifestation of a fibroproliferative disease characterized by chronic inflammation that is induced following skin injury." | 1.91 | IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation. ( Chao, H; He, J; Hsu, P; Liu, H; Ma, H; Tang, Q; Wu, R; Xu, S; Zeng, R; Zheng, L; Zhou, Y, 2023) |
| "The quality of scars has become an important outcome of burn care." | 1.91 | A clinimetric assessment of the validity and reliability of 3D technology for scar surface area measurement. ( de Vet, HCW; Doomen, MCHA; Gevers, T; Karaoglu, S; Meij-de Vries, A; Niessen, FB; Pijpe, A; Rijpma, D; van Zuijlen, PPM, 2023) |
| "This abnormal hyperplasia is due to the chronic inflammatory reaction in the dermis caused by injury." | 1.91 | [Status of diagnosis and treatment of hypertrophic scar and keloid]. ( Zang, MQ, 2023) |
| "Laser combined with radiotherapy is a new comprehensive therapy comprising ablative lasers and radiotherapy for keloids." | 1.91 | Laser Combined with Radiotherapy for Keloid Treatment: A Novel and Efficient Comprehensive Therapy with a Lower Recurrence Rate. ( Chen, ZA; Gao, Z; Lin, X; Ma, QY; Wang, WB; Wu, XL; Xia, LL; Xie, CH; Yang, YT; Zhao, Q, 2023) |
| "Keloids are formed due to abnormal hyperplasia of the skin connective tissue." | 1.91 | Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model. ( Chen, W; Chen, X; Gan, W; Huang, J; Qin, X; Wang, X; Yang, R; Zheng, W; Zhou, S, 2023) |
| "Keloids are pathological scars from exuberant fibroproliferative collagen response and excessive extracellular matrix production usually extending beyond the original wound margins." | 1.91 | Chest Wall Keloids Depicted by 18 F-Piflufolastat PET/CT Imaging. ( Martinez, F; Nguyen, A; Nguyen, BD, 2023) |
| "Manual scar treatment includes various techniques of therapy." | 1.91 | Effectiveness of various methods of manual scar therapy. ( Garncarczyk, A; Lubczyńska, A; Wcisło-Dziadecka, D, 2023) |
| "A keloid is a classic fibrotic skin disease characterized by excessive deposition of extracellular matrix (ECM)." | 1.91 | Osteomodulin contributes to keloid development by regulating p38 MAPK signaling. ( Bi, J; Chen, H; Li, Q; Liu, Y, 2023) |
| "In addition, dasatinib-treated keloid fibroblasts conditioned medium reduced procollagen and p16 expression in cultured keloid fibroblasts." | 1.91 | Dasatinib Attenuates Fibrosis in Keloids by Decreasing Senescent Cell Burden. ( Chung, JH; Darmawan, CC; Hur, K; Kusumaningrum, N; Lee, SH; Mun, JH, 2023) |
| "Both keloids and fibroids are fibroproliferative conditions that have been reported to be more prevalent among Blacks than Whites, and they share similar fibrotic tissue structures, including extracellular matrix composition, gene expression, and protein profiles." | 1.91 | Keloids, hypertrophic scars, and uterine fibroid development: a prospective ultrasound study of Black and African American women. ( Baird, DD; Gerety, M; Harmon, QE; Langton, CR, 2023) |
| "Keloid is a type of benign fibrous proliferative tumor characterized by excessive scarring." | 1.91 | Keloid Core Factor CTRP3 Overexpression Significantly Controlled TGF- ( Dou, H; He, L; Jia, J; Shu, M; Yu, X; Zhu, C, 2023) |
| "No keloid recurrence was observed during the follow-up period." | 1.91 | Surgical Treatment for Chest "Lock" Keloid Using Autologous Split-Thickness Skin Grafting and Postoperative Radiotherapy. ( Chen, XD; Cui, XM; Fu, ML; Pachuau, L; Wu, XY, 2023) |
| "Ear keloids are disfiguring disorders resistant to various treatments." | 1.91 | Surgical Core Excision With Tongue Flap Closure in Combination With Electron Beam Radiotherapy in the Treatment of Ear Keloids. ( Ahmednaji, NM; Chen, XD; Wang, YX; Wu, XY, 2023) |
| "Usually, keloids are considered and treated as a single entity but clinical observations suggest heterogeneity in keloid morphologies with distinction of superficial/extensive and nodular entities." | 1.91 | Evidence of inter- and intra-keloid heterogeneity through analysis of dermal fibroblasts: A new insight in deciphering keloid physiopathology. ( Benssussan, A; Boccara, D; Boismal, F; Bouaziz, JD; DE LA Grange, P; Ferrero, L; Gentien, D; Henry, E; Michel, L; Mimoun, M; Serror, K; Sintes, M; Thery, M; Vianay, B, 2023) |
| "Keloid is a pathological scar formed by abnormal wound healing, characterized by the persistence of local inflammation and excessive collagen deposition, where the intensity of inflammation is positively correlated with the size of the scar formation." | 1.91 | Revealing the roles of glycosphingolipid metabolism pathway in the development of keloid: a conjoint analysis of single-cell and machine learning. ( Chen, G; Chen, L; Chi, H; Cui, Z; Du, Y; Gao, B; Song, B; Yu, Z; Zheng, Y; Zhu, Y, 2023) |
| "Skin fibrosis is a common pathological manifestation in systemic sclerosis (SSc), keloid, and localized scleroderma (LS) characterized by fibroblast activation and excessive extracellular matrix (ECM) deposition." | 1.91 | Enhancement of Zyxin Promotes Skin Fibrosis by Regulating FAK/PI3K/AKT and TGF-β Signaling Pathways via Integrins. ( Gong, Y; Huang, Y; Jiang, S; Lin, J; Liu, J; Liu, Q; Ma, Y; Pu, W; Shi, X; Tang, Y; Wang, J; Wu, W; Zhang, Y; Zhao, H, 2023) |
| "Keloid is a heterogeneous disease featured by the excessive production of extracellular matrix." | 1.91 | UCHL1 aggravates skin fibrosis through an IGF-1-induced Akt/mTOR/HIF-1α pathway in keloid. ( Guo, C; Huang, J; Liang, L; Qiu, X; Tan, G; Wang, L; Xie, Y; Zheng, J, 2023) |
| " Combined with knowledge of the relevant literature, the mechanisms, types, and timing and dose, and reflect on balancing of recurrence rates and complications to deepen our understanding of the disease." | 1.91 | Rare Complication of Massive Depigmentation After Postoperative Treatment of Giant Keloid Combined With Strontium-90. ( Li, J; Liu, J; Wang, X; Wang, Y; Zhang, W; Zhang, Z, 2023) |
| " Intra-lesional injection of triamcinolone acetonide (TAC) in combination with 5-fluorouracil (5-FU) is a commonly used pharmacological regimen and long-term repeated injections can achieve sustained inhibition of keloid proliferation." | 1.91 | Deciphering the single-cell transcriptome network in keloids with intra-lesional injection of triamcinolone acetonide combined with 5-fluorouracil. ( Hao, Y; Kuang, X; Liang, Z; Liu, H; Shan, M; Wang, Y; Xia, Y, 2023) |
| "Keloids are known to recur and can cause severe cosmetic, functional, and psychological impairments." | 1.91 | Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation. ( Datema, FR; Rothuizen, LT; Saridin, J; Timmer, FCA; van Zijl, FVWJ, 2023) |
| "Keloids are benign skin lesions that gradually invade the surrounding normal tissue, and no treatment has proven curative." | 1.91 | Preliminary clinical observations on autologous cultured skin fibroblasts transplantation in the treatment of keloids: a case report. ( Han, X; Hu, SD; Ji, DS; Liu, Y; Zhao, YM, 2023) |
| "Keloids are benign skin tumors resulting from the excessive proliferation of connective tissue in wound skin." | 1.91 | [Keloid nomogram prediction model based on weighted gene co-expression network analysis and machine learning]. ( Li, Z; Liang, H; Tian, B, 2023) |
| "Enalapril and TAA were injected intralesionally in one session per month for three sessions." | 1.91 | Safety and efficacy of intralesional injection of enalapril versus triamcinolone acetonide in the treatment of keloids. ( Eltahlawy, S; Hamada Mohamed, B; Marzouk, WA; Mohamad, NE, 2023) |
| "Twenty-six recurrences were observed, and the 1-, 3-, and 5-year local control rates were 93%, 81%, and 73%, respectively." | 1.91 | Risk factors for recurrence after keloid surgery with electron radiotherapy. ( Liu, C, 2023) |
| "Keloid-associated pruritus is a common manifestation and has negative impacts on quality of life." | 1.91 | Pruritus in keloid scars: mechanisms and treatments. ( Biazus Soares, G; Mahmoud, O; Yosipovitch, G, 2023) |
| "First-line treatment of keloids consists of intralesional needle injections with corticosteroids, but generally entails multiple painful sessions, resulting in variable clinical outcomes." | 1.91 | Needle-free electronically controlled jet injection with corticosteroids in recalcitrant keloid scars: a retrospective study and patient survey. ( Bik, L; Elmzoon, I; Prens, EP; van Doorn, MBA; Wolkerstorfer, A, 2023) |
| "Patients with keloids are often younger than 30 years old and have darker skin." | 1.91 | Efficacy of a multimodal approach of laser therapy for earlobe keloids management in dark population. ( Bonan, P; Conforti, C; Crisman, G; Fusco, I; Piccolo, D, 2023) |
| "Among 56 treated keloids, 89." | 1.91 | Ear keloids: An innovative 3-steps combined treatment. ( Alessandro, G; Bruno, B; Claudio, C; Daniele, B; Domenico, P; Fabrizio, M; Giuliana, C; Matteo, TC, 2023) |
| "Dermatologists may want to consider treating keloids that cover a large area with systemic dupilumab, a therapy with an established, reassuring safety profile." | 1.91 | Successful Treatment of Keloids and Hypertrophic Scars With Systemic and Intralesional Dupilumab. ( Cobos, G; LaChance, AH; Lee, MS; Mazori, DR; Merola, JF; Min, MS; Vleugels, RA, 2023) |
| "Keloid is considered as a tumor-like skin disease with multiple aetiologies including immunological factors and mechanical microenvironment." | 1.72 | Important role of mechanical microenvironment on macrophage dysfunction during keloid pathogenesis. ( Gao, Z; Liu, W; Wang, W; Wu, X; Zhou, B, 2022) |
| "Of the 40 patients for a total of 41 treated keloids in the first group, 85." | 1.72 | Combined laser treatment for ear keloids: Case series: Comparison between two mini-invasive protocols: Comparison between two mini-invasive protocols. ( Bovani, B; Clementoni, MT; Conforti, C; Crisman, G; Gennai, A; Melfa, F; Piccolo, D, 2022) |
| "Keloids are skin lesions which result from an aberration in the physiological healing process marked with overgrowth of collagen fibers." | 1.72 | Fully Digital Workflow for Fabrication of A 3D Printed Ear Stent for Auricular Keloids: A Technique Article. ( Abrego, I; Hamdan, S; Lindsey, JT; Nejat, AH; Vitter, R, 2022) |
| "Keloids are intractable scar diseases and sometimes undergo hospitalization." | 1.72 | Clinical status of hospitalized keloid cases from 2013 to 2018. ( Gan, L; Kong, W; Shi, Y; Sun, Y; Tang, H; Wang, H; Xia, Z; Xiao, Y; Zhu, Z, 2022) |
| "Keloid is a benign dermal tumor characterized by abnormal proliferation and invasion of fibroblasts." | 1.72 | Identification of Hub Genes of Keloid Fibroblasts by Coexpression Network Analysis and Degree Algorithm. ( Huang, Z; Jiang, R; Jin, H; Li, X, 2022) |
| "Ear keloids are abnormal continuously growing healing process following cutaneous injury." | 1.72 | The outcome of postoperative radiation therapy following plastic surgical resection of recurrent ear keloid: a single institution experience. ( Al-Gendi, R; Al-Mohsen, S; Elawadi, AA; Mohamed, R; Wafa, A; Wani, S, 2022) |
| "Keloid is a skin disease marked by fibroplasia, and fibroblasts viability plays a considerable part in keloid." | 1.72 | Silencing circular RNAPTPN12 promoted the growth of keloid fibroblasts by activating Wnt signaling pathway via targeting microRNA-21-5p. ( Li, T; Liu, F; Zhan, X, 2022) |
| "Keloid is a skin fibroproliferative disease currently having no uniformly successful treatment." | 1.72 | LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen. ( Chen, L; Cheng, X; He, Y; Jia, C; Li, S; Su, Y; Yin, B, 2022) |
| " The average radiation dosage was 1578." | 1.72 | Optimizing surgical outcome of auricular keloid with a novel multimodal approach. ( Hung, YT; Lin, SM; Ng, CY; Tzeng, IS, 2022) |
| "Keloids are disfiguring, hypertrophic scars with yet poorly understood pathomechanisms, which could lead to severe functional impairments." | 1.72 | Schwann cells contribute to keloid formation. ( Ankersmit, HJ; Bormann, D; Copic, D; Direder, M; Farlik, M; Golabi, B; Haslik, W; Hoetzenecker, K; Klas, K; Laggner, M; Mildner, CS; Mildner, M; Pfisterer, K; Radtke, C; Shaw, L; Tschachler, E; Vorstandlechner, V; Weiss, T, 2022) |
| "Keloids are benign fibrous growths that are caused by excessive tissue build-up." | 1.72 | Risk factors associated with the progression from keloids to severe keloids. ( Cen, Y; Deng, K; Li, W; Liu, R; Wang, R; Xiao, H; Xu, X, 2022) |
| "Keloid is commonly regarded as a benign skin tumour." | 1.72 | Tissue chondrification and ossification in keloids with primary report of five cases. ( Gao, Z; Li, Q; Liu, W; Tu, T; Wang, W; Wu, X, 2022) |
| "Keloids are an excessive tissue response to dermal damage, characterized by uncontrolled growth and a high recurrence rate after various treatments." | 1.72 | Exosomes from human adipose-derived mesenchymal stem cells inhibit production of extracellular matrix in keloid fibroblasts via downregulating transforming growth factor-β2 and Notch-1 expression. ( Bi, J; Huo, R; Li, J; Li, Z; Wang, S, 2022) |
| "Keloids are benign fibroproliferative skin disorders characterized by chronic inflammation." | 1.72 | Secondary Cutaneous Ossification in Keloids of the Lower Abdomen: A Report of Two Cases. ( Ansai, SI; Ogawa, R; Tosa, M, 2022) |
| "Keloid is a pathological skin scar formation with complex and unclear molecular pathology mechanism." | 1.72 | Quantitative proteomics approach reveals novel biomarkers and pathological mechanism of keloid. ( Bergquist, J; Chi, X; Deng, T; Hu, W; Liu, J; Mi, J; Wang, H; Wang, Y; Yang, C; Yang, X; Zhang, C; Zhang, H; Zhu, Y, 2022) |
| "Keloids are "tumor-like" scars that grow beyond the boundary of injury." | 1.72 | TRAF3IP2 regulated by FOXO4 affects fibroblast proliferation, migration, and extracellular matrix deposition in keloid through the TGF-β1/Smad pathway. ( Li, B; Yan, Q, 2022) |
| "Results of recurrence rate varied by specific treatment modality; keloid excision yielded a rate of only 54%, keloid excision with postoperative radiation yielded a rate of 83%, keloid excision with intraoperative triamcinolone injection yielded a rate of 33%, and keloid excision with a combination of intraoperative triamcinolone injection and postoperative radiation yielded a rate of 33%." | 1.72 | Recurrence of Primary and Secondary Keloids in a Select African American and Afro-Caribbean Population. ( Margiotta, E; Ramras, S; Shteynberg, A, 2022) |
| "Keloids have always been a difficult problem in the clinic." | 1.72 | Inhibiting Warburg Effect Can Suppress the Biological Activity and Secretion Function of Keloid Fibroblasts. ( Fan, J; Gan, C; Huang, R; Jiao, H; Liu, L; Su, Z; Tian, J; Yang, Z, 2022) |
| "Keloids are a fibrotic skin disorder caused by abnormal wound healing and featuring the activation and expansion of fibroblasts beyond the original wound margin." | 1.72 | ASC-J9 Blocks Cell Proliferation and Extracellular Matrix Production of Keloid Fibroblasts through Inhibiting STAT3 Signaling. ( Chan, H; Chen, TC; Hong, YK; Hsu, CK; Huang, YL; Hung, KS; Lin, YC; Liu, YT; Pai, TP; Wu, CH, 2022) |
| "The pathogenesis of keloids has not been definitively clarified and treatment is often protracted and less than satisfactory." | 1.72 | [Treatment of keloids]. ( Haubner, F; Oettgen, F, 2022) |
| "A total of 7 DFSPs, nine dermatofibromas (DF, including four cases of cellular variant [CDF]), 12 keloids, and one nodular fasciitis were enrolled." | 1.72 | Diagnosis and differential diagnosis of dermatofibrosarcoma protuberans: Utility of high-resolution dynamic contrast-enhanced (DCE) MRI. ( Gu, Q; Huang, R; Li, P; Li, Y; Song, L; Tang, M; Yu, Q; Zhang, X; Zhou, N; Zhu, Y, 2022) |
| "Keloids are a chronic disease and cause pain, pruritus, and limitation of motion." | 1.72 | A Novel Method of Steroid Delivery to Improve the Efficacy of Intralesional Injection in Keloid Treatment. ( Cho, MY; Chung, KY; Roh, MR; Song, A, 2022) |
| "Keloids are benign fibroproliferative diseases with abnormally proliferated bulges beyond the edge of the skin lesions, and they are characterized by uncontrolled fibroblast proliferation and excessive extracellular matrix deposition in the dermis." | 1.72 | TSP1 promotes fibroblast proliferation and extracellular matrix deposition via the IL6/JAK2/STAT3 signalling pathway in keloids. ( Chen, JY; Deng, CC; Feng, QL; Gu, JJ; Pan, HH; Xu, XY; Yang, B; Zheng, WY, 2022) |
| "Keloids are benign fibroproliferative tumors that display many cancer-like characteristics, such as progressive uncontrolled growth, lack of spontaneous regression, and extremely high rates of recurrence." | 1.72 | Downregulation of PLK4 expression induces apoptosis and G0/G1-phase cell cycle arrest in keloid fibroblasts. ( Fu, R; Huang, RL; Li, Q; Liu, C; Wang, X; Yan, Y; Yang, J, 2022) |
| "Keloid is a benign proliferative disease characterized by excessive deposition of extracellular matrix collagen during skin wound healing." | 1.72 | Identification and validation of HOXD3 and UNC5C as molecular signatures in keloid based on weighted gene co-expression network analysis. ( Chen, L; Liu, Y; Qi, S; Tang, J; Wang, H; Wang, P; Xie, J; Zhou, Z, 2022) |
| "BACKGROUND A keloid is a pathological scar hyperplasia that is affected by genetic and environmental factors." | 1.72 | Expression of the GZMB Gene Polymorphism, SNP rs8192917, in 990 Han Chinese Patients with Postoperative Keloids. ( Du, H; Guo, Y; Hao, X; Wang, J; Wen, X, 2022) |
| "Keloids are benign fibroproliferative skin tumors." | 1.72 | Circular RNA hsa_circ_0043688 serves as a competing endogenous RNA for microRNA-145-5p to promote the progression of Keloids via Fibroblast growth factor-2. ( Li, X; Li, Y; Liu, Y; Ni, Z; Song, J; Wang, X; Zhu, F, 2022) |
| "Although chronic inflammation is known to be associated with the excessive inflammation in keloid tissue, there are few studies on the role of autophagy in the pathogenesis of keloid." | 1.72 | IL-17 Induces Autophagy Dysfunction to Promote Inflammatory Cell Death and Fibrosis in Keloid Fibroblasts ( Cho, KH; Cho, ML; Choi, JW; Lee, AR; Lee, CR; Lee, JH; Lee, SY, 2022) |
| "We present a case of ectopic breast carcinoma (EBC) in middle aged man mimicking keloid." | 1.72 | Primary Ectopic Breast Carcinoma in Man Mimicking Keloid. ( Alakloby, G; Alakloby, O; Algamdi, B; Alharbi, N; Alqahtani, J; Alzoabi, N; Busbait, S; Hajla, M, 2022) |
| "Relapse of keloids is common after corticosteroid injection in patients with oily skin." | 1.72 | Microneedle delivery of botulinum toxin type A combined with hyaluronic acid for the synergetic management of multiple sternal keloids with oily skin: A retrospective clinical investigation. ( Fan, H; Min, P; Peng, Y; Zhang, S; Zhang, Y, 2022) |
| "Keloids are the result of abnormal wound healing, and they differ from the normal skin of the patient in the level of blood perfusion and the degrees of inflammation, hypoxia, regeneration of vessels, and expression of sensory receptors." | 1.72 | Relative perfusion index: An objective, quantitative and noninvasive method for evaluating the severity of keloids. ( Li, S; Long, X; Wang, X; Zhang, M, 2022) |
| "Keloids are considered disorders of fibroproliferation characterized by accumulation of collagen fibers in hypodermis and dermis, caused by inflammation, surgery, and trauma." | 1.72 | Keloid therapy: A neoteric comparative study. ( Bessar, H; Khater, EM; Khattab, FM, 2022) |
| "Keloid has brought great trouble to people and currently has no uniformly successful treatment." | 1.72 | Identifying miRNAs Associated with the Progression of Keloid through mRNA-miRNA Network Analysis and Validating the Targets of miR-29a-3p in Keloid Fibroblasts. ( He, Y; Jia, C; Lan, J; Li, S; Lian, W; Wang, P; Yin, B; Zhang, Z, 2022) |
| "Keloids are a common type of pathological scar as a result of skin healing, which are extremely difficult to prevent and treat without recurrence." | 1.72 | Exosomes released by melanocytes modulate fibroblasts to promote keloid formation: a pilot study. ( Shao, J; Shen, Z; Sun, J; Xu, J, 2022) |
| "A keloid is a fibroproliferative disorder of unknown etiopathogenesis that requires ill-defined treatment." | 1.72 | Identification and characterization of four immune-related signatures in keloid. ( Chen, X; Li, J; Liang, B; Pi, X; Wang, X; Yang, R; Zhang, P; Zhou, S; Zhou, X, 2022) |
| "The pathogenesis of keloids has not been definitively clarified and treatment is often protracted and less than satisfactory." | 1.72 | [Treatment of keloids at the ear]. ( Haubner, F; Oettgen, F, 2022) |
| "Background: A keloid is a benign skin tumor that extends beyond the initial injury area, and its pathologic mechanism remains unclear." | 1.72 | The Role of CD28 and CD8 ( Feng, C; Hao, Y; Liu, H; Shan, M; Song, K; Wang, Y, 2022) |
| "Psoriasis is a papulosquamous disorder that causes significant social and psychological trauma to the patient." | 1.72 | Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis. ( Attwa, E; Essam, R; Khater, MH; Selim, HM, 2022) |
| "Keloids affects predominantly young adults with single anatomical site being the commonest presentation, with the chest mostly affected and the flat pattern commonly observed." | 1.72 | Keloids in Darkly Pigmented Skin: Clinical Pattern and Presentation at a Tertiary Health Facility, Southwest Nigeria. ( Ajani, AA; Akinboro, AO; Alo, AG; Olanrewaju, FO; Olasode, OA; Oripelaye, MM, 2022) |
| "Cryosurgery, the most common treatment for keloids, causes skin traumas." | 1.72 | Ulvan-Based Nanofibrous Patches Enhance Wound Healing of Skin Trauma Resulting from Cryosurgical Treatment of Keloids. ( Ioannou, E; Karalis, V; Kikionis, S; Koromvoki, M; Kyritsi, A; Panagiotopoulos, A; Polichronaki, E; Rallis, M; Roussis, V; Stratigos, A; Tagka, A; Vitsos, A, 2022) |
| "The present study aims to investigate the effectiveness, recurrence, and adverse reaction rates of isotope phosphorus-32 dressings combined with diprospan and mucopolysaccharide polysulphate cream in the treatment of keloids." | 1.72 | Observation of the clinical efficacy of isotope phosphorus-32 dressing combined with diprospan and mucopolysaccharide polysulphate cream in the treatment of keloids. ( Hu, FC; You, Y; Zhang, L; Zhuang, BY, 2022) |
| "Fibrosis is a common pathophysiological response of many tissues and organs subjected to chronic injury." | 1.72 | Skin fibrosis associated with keloid, scleroderma and Jorge Lobo's disease (lacaziosis): An immuno-histochemical study. ( Kanashiro-Galo, L; Mosser, DM; Pagliari, C; Quaresma, JAS; Silva, AMG; Sotto, MN; Tafuri, WL; Tomokane, TY, 2022) |
| "Keloids and hypertrophic scars are cosmetic problems with significant morbidity." | 1.72 | Assessment of intralesional injection of botulinum toxin type A in hypertrophic scars and keloids: Clinical and pathological study. ( Abd-El-Raheem, TA; El Hanbuli, HM; Hussein, HA; Khatery, BHM; Yassen, NN, 2022) |
| "Pyoderma gangrenosum is a rare neutrophilic inflammatory skin disorder commonly seen over lower limbs." | 1.72 | Brocq's geometric phagedena over penis with keloidal scars. ( A, S; Bhat, RM; Dandakeri, S; Fernandes, MS; Jayaraman, J, 2022) |
| "Six patients with recurred keloid were treated with keloid surgery and radiotherapy for the second time." | 1.72 | Skin endothelial cell and microcirculation function study in recurred keloids patients after keloid surgery and radiotherapy. ( Hao, Y; Li, W; Liu, H; Qiu, J; Shan, M; Wang, Y, 2022) |
| "Keloids and hypertrophic scars are characterized by abnormal fibroblast activation and proliferation." | 1.72 | The Role of Hippo Signaling Pathway and ILK in the Pathophysiology of Human Hypertrophic Scars and Keloids: An Immunohistochemical Investigation. ( Bravou, V; Kalbermatten, DF; Madduri, S; Nifora, M; Nikou, S; Petrou, IG, 2022) |
| "Keloid is a common pathological scar, which involves the regulation of immune microenvironment." | 1.72 | tRNA derived fragment tsRNA-14783 promotes M2 polarization of macrophages in keloid. ( Hu, Z; Wang, X, 2022) |
| "Keloid is a benign tumor with high recurrence rate; accordingly, complete surgical excision with adjuvant radiotherapy is one of the most effective treatments." | 1.72 | Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy. ( Chen, F; Chiang, CH; Huang, CJ; Huang, MY; Kuo, YR; Tang, JY, 2022) |
| "Acne vulgaris is a troubling skin disease known to have both physiologic and psychological effects on patients." | 1.72 | Acne Scars: An Update on Management ( Alajmi, A; Alazemi, M; Jfri, A; Ladha, MA, 2022) |
| "Skin fibrosis is a hallmark of a wide array of dermatological diseases which can greatly impact the patients' quality of life." | 1.72 | Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies. ( Almudéver, P; Alonso-Carpio, M; Cortijo, J; Marín, S; Milara, J; Montero, P; Peiró, T; Ribera, P; Roger, I, 2022) |
| "Keloids are fibroproliferative disorders, which seriously affect the quality of life of patients with keloids." | 1.72 | Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling. ( Guo, F; Hu, H; Mao, G; Zheng, J, 2022) |
| "Keloids and hypertrophic scars are abnormal responses to wound-healing." | 1.72 | Keloids and Hypertrophic Scars. ( Alvarenga, LRMG; Oliveira, GV; Ramos-e-Silva, M, 2022) |
| "Nodular scleroderma or keloidal morphea presenting in a linear distribution is even more uncommon." | 1.72 | Questions raised by a case of adult-onset linear nodular scleroderma. ( Hansen, CB; Jimenez, A; Marcelus, C; Sontheimer, RD; Zussman, J, 2022) |
| "Both keloids and migraines can cause physical exhaustion and discomfort in patients; they have similar pathophysiological pathways, that is, the transforming growth factor-β1 gene and neurogenic inflammation." | 1.72 | Migraines and keloids: a 15-year Taiwan claim database analysis. ( Lu, CC; Lu, YY; Qin, H; Wu, CH; Wu, MK; Zhang, CL, 2022) |
| "Keloid is a benign well-demarcated overgrowth of fibrotic tissue which extends beyond the original boundaries of a defect." | 1.72 | Role of vitamin D in treatment of keloid. ( Ali, SM; Hafiz, HSA; Mamdouh, M; Omar, GA, 2022) |
| "Keloids are essentially different from other types of scars in terms of energy metabolism." | 1.72 | Warburg effect in keloids: A unique feature different from other types of scars. ( Chen, Y; Fan, J; Gan, C; Jiao, H; Liu, L; Su, Z; Tian, J; Yang, Z; Zhang, T, 2022) |
| "Recently, pulsed dye laser (PDL) combined with triamcinolone intralesional injection (TAILI) has been introduced for surgical scar prevention." | 1.72 | Evaluating outcomes of pulsed dye laser therapy combined with intralesional triamcinolone injection after surgical removal of hypertrophic cesarean section scars. ( Hong, JS; Huh, CH; Kim, JW; Na, JI; Shin, JW; Yoon Park, J, 2022) |
| "Keloids are a benign dermal fibrotic disorder with features similar to malignant tumors." | 1.72 | Single-Cell RNA-Sequencing Reveals Lineage-Specific Regulatory Changes of Fibroblasts and Vascular Endothelial Cells in Keloids. ( Chen, J; Chen, W; Li, Z; Liu, X; Long, X; Ma, B; Meng, T; Yu, N; Zeng, Q; Zhou, Z, 2022) |
| "Keloid is a fibroproliferative disorder resulting from trauma, characterized by abnormal activation of keloid fibroblasts and excessive deposition of extracellular matrix (ECM)." | 1.72 | Protein tyrosine phosphatase 1B regulates fibroblasts proliferation, motility and extracellular matrix synthesis via the MAPK/ERK signalling pathway in keloid. ( Deng, X; Liu, J; Qi, F; Qian, L; Wang, L; Wang, Q; Wei, C; Yang, Y, 2022) |
| "Keloids are benign skin tumors characterized by aggressive growth." | 1.62 | Kindlin-2 promoted the progression of keloids through the Smad pathway and Fas/FasL pathway. ( Huang, S; Liao, J; Liu, F; Luo, X; Shi, G; Wen, W, 2021) |
| "Keloid is an aberrant scarring process of the skin, characterized by excessive extracellular matrix synthesis and deposition." | 1.62 | Multi-Antigen Imaging Reveals Inflammatory DC, ADAM17 and Neprilysin as Effectors in Keloid Formation. ( Bauerschmitz, J; Baur, AS; Fröhlich, W; Kirr, M; Ostalecki, C; Pitiot, A; Plosnita, B; Rath, M; Schliep, S, 2021) |
| "Keloid is a type of unusually raised scar." | 1.62 | Botulinum toxin A promotes the transdifferentiation of primary keloid myofibroblasts into adipocyte-like cells. ( Dai, X; Lei, TC, 2021) |
| "Keloid is a benign fibro-proliferative dermal tumor formed by an abnormal scarring response to injury and characterized by excessive collagen accumulation and invasive growth." | 1.62 | Integrated bioinformatics analysis of core regulatory elements involved in keloid formation. ( Jin, M; Jin, Z; Li, C; Luo, Y; Pi, L, 2021) |
| "Keloids are a common form of pathologic wound healing and are characterized by an excessive production of extracellular matrix." | 1.62 | Tauroursodeoxycholic Acid Decreases Keloid Formation by Reducing Endoplasmic Reticulum Stress as Implicated in the Pathogenesis of Keloid. ( Jun, S; Kang, YE; Kim, CS; Kim, S; Lee, SE; Nagar, H; Oh, SH; Shin, C; Yeo, MK; Yi, S; Yi, YS, 2021) |
| " Contact cryosurgery is a safe technique for the management of earlobe keloids with tolerable side effects." | 1.62 | Efficacy and Safety of Contact Cryosurgery in the Treatment of Earlobe Keloids. ( Benmously, R; Fenniche, S; Hammami, H; Jannet, SB; Zaouak, A, 2021) |
| "The etiology of keloid is largely unknown; however, AD and keloid share inflammatory pathways characterized by T-helper cell 2 cytokines and increased dermal fibroblast activity." | 1.62 | The increased prevalence of keloids in atopic dermatitis patients with allergic comorbidities: a nationwide retrospective cohort study. ( Ahn, HJ; Jeong, SJ; Kwon, HE; Shin, MK, 2021) |
| "Keloid is a benign fibroproliferative skin tumor." | 1.62 | Bioinformatics study on different gene expression profiles of fibroblasts and vascular endothelial cells in keloids. ( Lin, G; Wang, Z; Zheng, W, 2021) |
| "However, the clinical treatment of keloid, such as drug injection treatment, surgical resection, cryotherapy, laser treatment and other therapeutic effects are poor." | 1.62 | Targeting of keloid with TRAIL and TRAIL-R2/DR5. ( Hu, Z; Lu, X; Pan, B; Sun, P, 2021) |
| "We used microneedles to treat keloid because this method has the feasibility of self-administration without pain." | 1.62 | Topical delivery of 5-fluorouracil-loaded carboxymethyl chitosan nanoparticles using microneedles for keloid treatment. ( Kim, YC; Park, J, 2021) |
| "After treatment, the mean keloid VSS of the injection side became 2." | 1.62 | Laser-assisted topical steroid application versus steroid injection for treating keloids: A split side study. ( Abd El-Dayem, DH; Elsaie, ML; Hanafy, NS; Nada, HA, 2021) |
| "SE and SE + RT recurrence were 37." | 1.62 | Contemporary treatment of keloids: A 10-year institutional experience with medical management, surgical excision, and radiation therapy. ( Akinbiyi, T; Barrette, LX; Broach, RB; Butler, PD; Davis, HD; Jones, JA; Kozak, GM; Maxwell, R; Rios-Diaz, AJ; Tilahun, ED, 2021) |
| "A keloid is a type of pathological scar often caused by abnormal tissue repair after a skin injury and is more common in genetically susceptible individuals." | 1.62 | Downregulation of Epac Reduces Fibrosis and Induces Apoptosis Through Akt Signaling in Human Keloid Fibroblasts. ( Bao, X; Feng, Y; Liu, S; Lv, W; Ren, Y; Yi, Z; Zhang, Q, 2021) |
| "A total of 59 patients with 110 untreated keloids on the anterior chest were enrolled in this study." | 1.62 | Heterogeneous Features of Keloids Assessed by Laser Speckle Contrast Imaging: A Cross-Sectional Study. ( Chen, C; Long, X; Wang, X; Wang, Y; Yu, N; Zhang, M; Zhang, W, 2021) |
| "Keloids are benign tumours caused by abnormal wound healing driven by increased expression of cytokines, including activin A." | 1.62 | Potential treatment of keloid pathogenesis with follistatin 288 by blocking the activin molecular pathway. ( de Kretser, D; Ham, S; Harrison, C; Southwick, G; Temple-Smith, P; Wallace, EM, 2021) |
| "Keloid is a benign fibroproliferative tumor of the skin caused by abnormal wound healing process after skin injury." | 1.62 | NEAT1 Knockdown Inhibits Keloid Fibroblast Progression by miR-196b-5p/FGF2 Axis. ( Chen, F; Deng, P; Feng, X; Qi, Y; Wen, H; Yang, J, 2021) |
| "Keloids are characterized by fibroblast activation and altered architecture of extracellular matrix (ECM)." | 1.62 | Impaired collagen fibril assembly in keloids with enhanced expression of lumican and collagen V. ( Gao, Z; Liu, W; Tu, T; Wang, W; Wu, X; Zhou, B, 2021) |
| "Keloids are a skin fibrotic disease that cause a number of problems for reconstructive surgeons." | 1.62 | miR-194-5p serves a suppressive role in human keloid fibroblasts via targeting NR2F2. ( Jiang, S; Xu, Q, 2021) |
| "Keloids are a skin fibroproliferative condition characterized by the hyperproliferation of fibroblasts and the excessive deposition of extracellular matrix (ECM) components." | 1.62 | Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway. ( Hu, W; Luo, X; Lv, W; Ren, Y; Wu, M; Wu, Y; Zhang, Q, 2021) |
| "Recently, successful treatment of keloids has been reported using the Nd:YAG laser in conjunction with 5-fluorouracil and intralesional corticosteroids." | 1.62 | Treatment of Pain in Keloids Using Only a Long-Pulsed 1064 nm Nd:YAG Laser. ( Bakus, AD; Garden, BC; Garden, JM; Jones, VA; Lai, O; Patel, PM, 2021) |
| "Keloid is troublesome for patients' skin appearance and mental health, although it is a benign tumor." | 1.62 | LncRNA HOXA11-AS Aggravates Keloid Progression by the Regulation of HOXA11-AS-miR-205-5p-FOXM1 Pathway. ( Gao, Y; Ma, Y; Su, X; Wang, Q, 2021) |
| "Recurrence rates of keloids have generally been reported at one time point." | 1.62 | Long-term outcomes and recurrence-free interval after the treatment of keloids with a standardized protocol. ( Funayama, E; Hayashi, T; Ishikawa, K; Maeda, T; Murao, N; Osawa, M; Yamamoto, Y, 2021) |
| "The successful treatment of keloids is a great challenge in the plastic surgery field." | 1.62 | Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway. ( Chen, ZY; Liu, XM; Wang, XM; Wang, Y, 2021) |
| "Keloid is a type of skin fibroproliferative disease, characterized by excessive deposition of collagen in the extracellular matrix, myofibroblast activation and invasive growth to the surrounding normal skin tissue." | 1.62 | Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro. ( Luo, X; Lv, W; Ren, Y; Wu, M; Wu, Y; Yu, J; Zhang, Q, 2021) |
| "Keloid is a skin disease characterized by fibrous hyperplasia, which is often difficult to cure." | 1.62 | LncRNA H19 promotes keloid formation through targeting the miR-769-5p/EIF3A pathway. ( Li, G; Liu, L; Sun, N; Xu, L, 2021) |
| "Patients with keloids have increased odds risk of arthrofibrosis following primary TKA." | 1.62 | Arthrofibrosis after total knee arthroplasty: patients with keloids at risk. ( Flick, TR; Hodo, TW; Patel, AH; Sanchez, FL; Sherman, WF; Wang, CX, 2021) |
| "Keloid is a kind of pathological skin scar with unclear molecular pathology." | 1.62 | Identification of differentially expressed circular RNAs in keloid and normal skin tissue by high-throughput sequencing. ( Liu, N; Ma, J; Song, N; Wu, P; Wu, X; Zhang, J, 2021) |
| "Keloids are characterized by disturbance of fibroblast proliferation and apoptosis, deposition of collagen, and upregulation of dermal inflammation cells." | 1.62 | The association between keloid and osteoporosis: real-world evidence. ( Lu, CC; Lu, YY; Qin, H; Wu, CH; Zhang, CL; Zhang, ZH, 2021) |
| "Keloids are characterized by increased deposition of fibrous tissue in the skin and subcutaneous tissue following an abnormal wound healing process." | 1.62 | Halofuginone regulates keloid fibroblast fibrotic response to TGF-β induction. ( Chatelain, B; Dirand, Z; Humbert, P; Isidoro, C; Lihoreau, T; Marty, P; Rolin, G; Secomandi, E; Senez, C; Tissot, M, 2021) |
| "Keloids are a type of aberrant skin scarring characterized by excessive accumulation of collagen and extracellular matrix (ECM), arising from uncontrolled wound healing responses." | 1.62 | Downregulation of CR6-interacting factor 1 suppresses keloid fibroblast growth via the TGF-β/Smad signaling pathway. ( Choi, SJ; Jeon, BH; Kim, CS; Kim, S; Lee, I; Nagar, H; Oh, SH; Piao, S, 2021) |
| "Keloids are fibroproliferative disorders characterized by high recurrence rates, with few factors known to influence the same." | 1.62 | Does Keloid Histology Influence Recurrence? ( Agak, GW; Anzala, O; Nangole, FW; Ogeng'o, J; Ouyang, K; Zuriel, D, 2021) |
| " Our results showed that HA combined with red light irradiation treatment (HA-R-PDT) decreased KF viability, reduced KF collagen production and ECM accumulation, inhibited cell proliferation, suppressed cell invasion and induced cell apoptosis." | 1.62 | Antifibrotic effects of Hypocrellin A combined with LED red light irradiation on keloid fibroblasts by counteracting the TGF-β/Smad/autophagy/apoptosis signalling pathway. ( Guo, G; Niu, T; Shi, Y; Tian, Y; Tong, Y; Wang, G, 2021) |
| "At present, the consensus on the best treatment for keloids is the combination of clinical and surgical therapies, if necessary, associated with adjuvant radiotherapy like brachytherapy." | 1.62 | A retrospective study of hypofractionated radiotherapy for keloids in 100 cases. ( Wang, T; Wen, P; Wu, C; Yu, Y; Zhou, Y, 2021) |
| "Keloid and hypertrophic scars are skin fibrosis-associated disorders that exhibit an uncontrollable proliferation of fibroblasts and their subsequent contribution to the excessive accumulation of extracellular matrix (ECM) in the dermis." | 1.62 | Ameliorating Fibrotic Phenotypes of Keloid Dermal Fibroblasts through an Epidermal Growth Factor-Mediated Extracellular Matrix Remodeling. ( Anggradita, LD; Bae, J; Hur, SS; Hwang, NS; Hwang, Y; Kim, H; Lee, SJ; Nam, SM, 2021) |
| "Keloid is a benign tumor characterized by persistent inflammation, increased fibroblast proliferation, and abnormal deposition of collagen in the wound." | 1.62 | Phosphoproteome and Biological Evidence Revealed Abnormal Calcium Homeostasis in Keloid Fibroblasts and Induction of Aberrant Platelet Aggregation. ( Chen, J; Cheng, B; Guo, J; He, QY; Lin, X; Wang, T; Xu, P; Yan, Z; Zhang, W; Zheng, W; Zhong, J; Zhou, J, 2021) |
| "Keloids are fibroproliferative dermal tumors of unknown origin that are characterized by the overabundant accumulation of extracellular matrix (ECM) components." | 1.62 | The "Matrisome" reveals the characterization of skin keloid microenvironment. ( Chai, M; Gao, D; Leng, L; Li, M; Liu, B; Lv, L; Ma, J; Wang, W; Wu, Z; Zhang, S; Zhu, Y, 2021) |
| "There are few means to treat large keloid scars, as exeresis-even if partial-impedes direct closure without tension in the absence of a flap or a skin graft." | 1.62 | A new therapeutic protocol for the treatment of keloid scars: a retrospective study. ( Azoulay, L; Boccara, D; Chaouat, M; Chatelain, S; Mimoun, M; Serror, K, 2021) |
| "Keloids were assessed using the Vancouver Scar Scale (VSS) and LSCI." | 1.62 | Laser Speckle Contrast Imaging for the Objective Assessment of Blood Perfusion in Keloids Treated With Dual-Wavelength Laser Therapy. ( Long, X; Teng, Y; Ting, W; Wang, X; Xu, C, 2021) |
| "Keloids are fibroproliferative lesions resulting from an abnormal wound healing process due to pathological mechanisms that remain incompletely understood." | 1.62 | Analysis of HOX gene expression and the effects of HOXA9 overexpression in fibroblasts derived from keloid lesions and normal skin. ( Anness, MC; Combs, KA; Hahn, JM; McFarland, KL; Supp, DM, 2021) |
| "Keloid is a unique refractory syndrome characterized by a proliferation disorder of the fibroblasts." | 1.62 | Phenalen-1-one-mediated photodynamic therapy inhibits keloid graft progression by reducing vessel formation and promoting fibroblast apoptosis. ( Li, H; Li, Y; Liu, Z; Nie, Y; Shi, L; Wang, H; Wu, H; Zheng, W, 2021) |
| "Keloid is a skin disease characterized by exaggerated scar formation, excessive fibroblast proliferation, and excessive collagen deposition." | 1.62 | Risk of cancer development in patients with keloids. ( Chang, KL; Hong, CH; Lee, CH; Lu, YY; Tu, HP; Wu, CH; Yang, HJ; Yang, KC, 2021) |
| "Suppuration is a common complication of keloids occurring in patients with severe keloid disease and may arise from pilosebaceous occlusion and aseptic inflammation." | 1.62 | Suppurative keloids: a complication of severe keloid disease. ( Algain, M; Bagot, M; Delaleu, J; Duverger, L; Kourouma, S; Petit, A; Shourick, J; Tirgan, MH; Tounkara, T, 2021) |
| "Keloids are benign fibroproliferative skin tumors." | 1.62 | LINC01116 regulates proliferation, migration, and apoptosis of keloid fibroblasts by the TGF-β1/SMAD3 signaling via targeting miR-3141. ( Tan, M; Wu, D; Zhou, J; Zhou, Y, 2021) |
| "Keloids are common fibroproliferative tumors, and their treatment still represents a dilemma." | 1.62 | Intralesional pentoxifylline, triamcinolone acetonide, and their combination for treatment of keloid scars. ( Gamea, MM; Hegab, DS; Mahmoud, WH; Serag-Eldin, YMA, 2021) |
| "Keloid is a hyperplastic pathological scar of body caused by infection, trauma, and surgery or formed spontaneously for unknown reasons." | 1.62 | [Research advances on inflammatory responses involved in keloid development]. ( Lei, JA; Qin, ZL; Zhou, Y, 2021) |
| "Keloids are disfiguring pathological scars that could cause pain and pruritus." | 1.62 | Enhanced Drug Permeation into Human Keloid Tissues by Sonophoresis-Assisted Microneedling. ( Hu, T; Liu, W; Ning, X; Xia, L; Xu, C; Yang, Y, 2021) |
| "There was no recurrence in the 14 sites of pubic region." | 1.62 | Treatment of Keloid by Implantation of Tissue Expander beneath the Keloid Tissue. ( Ali, A; Xiao-Dong, C, 2021) |
| "Keloids are focal fibrotic responses to cutaneous trauma characterized by disordered collagen, which may be associated with elevated systemic fibrocyte levels and/or wound bed chemokine expression." | 1.62 | Systemic Fibrocyte Levels and Keloid Expression of the Chemoattractant CXCL12 Are Upregulated Compared With Patients With Normal Scar. ( Burdick, MD; Campbell, CA; Strieter, RM, 2021) |
| "Ear keloids are benign, fibrous proliferations due to excessive collagen synthesis and deposition." | 1.62 | Surgical approach in the management of ear keloids: our experience with 30 patients. ( Chandrashekar, BS; Madura, C; Nayak, PB; Raj, PR, 2021) |
| "Despite numerous existing treatments for keloids, the responses in the clinic have been disappointing, due to either low efficacy or side effects." | 1.62 | Evaluation of the Effects of Human Dental Pulp Stem Cells on the Biological Phenotype of Hypertrophic Keloid Fibroblasts. ( Chen, LM; Feng, HC; Friedrich, RE; Fu, LL; Gosau, M; Nada, OA; Smeets, R; Yan, M, 2021) |
| "The association between recurrence and size or CT densitometry parameters was analyzed for 64 lesions that could be followed up for 6 months or more." | 1.56 | Analyses of size and computed tomography densitometry parameters for prediction of keloid recurrence after postoperative electron beam radiation therapy. ( Arashiro, K; Ganaha, F; Iraha, S; Ishigami, K; Kusada, T; Maemoto, H; Murayama, S, 2020) |
| "Severe keloids are currently treated with surgical resection followed by radiation." | 1.56 | Geometric modeling and a retrospective cohort study on the usefulness of fascial tensile reductions in severe keloid surgery. ( Akaishi, S; Aoki, M; Dohi, T; Ogawa, R; Tsuge, T; Yamamoto, H, 2020) |
| "The pathogenesis of keloids has not been elucidated, and the disease is thought to be caused by abnormal secretion of proinflammatory mediators and irregular responses to other inflammatory signals mediated by keloid fibroblasts (KFs)." | 1.56 | IL-17 Induced Stromal Cell-Derived Factor-1 and Profibrotic Factor in Keloid-Derived Skin Fibroblasts via the STAT3 Pathway. ( Cho, ML; Choi, JW; Jung, KA; Kim, DS; Kim, EK; Lee, JH; Lee, SY; Moon, SJ; Seo, HB; Yang, SC; Yoo, JH, 2020) |
| "Keloids are caused by an imbalance between collagen matrix decomposition and production during wound repair." | 1.56 | Spontaneous symmetrical giant keloids at the bilateral labia majora: a case report. ( Dong, W; Huang, J; Long, X; Wang, X; Zhang, W, 2020) |
| "Keloids are dermal fibroproliferative disorders that characterized by over deposition of components of the extracellular matrix." | 1.56 | Correlation between serum IL 37 levels with keloid severity. ( Khattab, FM; Samir, MA, 2020) |
| " This article reports a rare successful treatment of a giant keloid in the anterior chest wall by multistage surgery combined with radiotherapy, which is why this case is meaningful." | 1.56 | Multi-stage surgery combined with radiotherapy for treatment of giant anterior chest wall keloid: A case report. ( Cheng, T; Fang, H; Li, P; Liu, Q; Meng, S; Qin, C; Qu, B; Wu, R; Yang, D; Yang, Z, 2020) |
| "Keloids are dermal fibroproliferative tumors that arise beyond the boundary of the original wound edges and invades adjacent tissue." | 1.56 | Chondroitin Sulfate Promotes the Proliferation of Keloid Fibroblasts Through Activation of the Integrin and Protein Kinase B Pathways. ( Aya, R; Ishiko, T; Katayama, Y; Kubota, H; Morimoto, N; Naitoh, M; Yamawaki, S, 2020) |
| "We present a rare case of lumbo-sacral angioleiomyoma in a 54-year-old man." | 1.56 | Angioleiomyoma of the lumbo-sacral region with unusual keloid-like collagen fibers. ( Magro, G; Salvatorelli, L; Vecchio, GM, 2020) |
| "Keloid is a benign dermal tumor with excessive hyperplasia and deposition of collagen." | 1.56 | Overexpression of miR-133a-3p inhibits fibrosis and proliferation of keloid fibroblasts by regulating IRF5 to inhibit the TGF-β/Smad2 pathway. ( Huang, Y; Jiang, L; Lin, L; Liu, J; Wang, P; Wang, X; Wang, Y, 2020) |
| "Risk of recurrence in previous reports and measures to guard against its occurrence are also discussed." | 1.56 | Are Prophylactic Measures Necessary to Prevent Recurrence of Penile Keloids? ( Abdelhalim, A; Atwa, AM; Dawaba, ME; Edwan, M; Hafez, AT; Helmy, TE; Soltan, MA, 2020) |
| "Hypertrophic scars and keloids are fibroproliferative lesions characterized by excessive collagen deposition." | 1.56 | Wnt Signaling Pathway Proteins in Scar, Hypertrophic Scar, and Keloid: Evidence for a Continuum? ( Chaudet, KM; Goyal, A; Nazarian, RM; Veprauskas, KR, 2020) |
| "Keloids are reactive or spontaneous fibroproliferative dermal tumors characterized by the exaggerated and uncontrolled accumulation of extracellular collagen." | 1.56 | Hypoxia and HIF-1α Regulate Collagen Production in Keloids. ( Kang, Y; Kumar, R; Njauw, CN; Rajadurai, A; Rajadurai, S; Roh, MR; Tsao, H; Zheng, Z, 2020) |
| "Keloids are firm, fibrous nodules that form on an individual's skin and are associated with difficult symptoms as well as high recurrence rates." | 1.56 | Combined surgical excision and electron external beam radiation improves the treatment of keloids: A descriptive study. ( Ma, J; Shen, H; Wang, Y; Zhang, Z, 2020) |
| "Three patients showed relapse and the recurrence rate was 7." | 1.56 | Continuous tension reduction to prevent keloid recurrence after surgical excision: Preliminary experience in Asian patients. ( Chen, B; Ding, J; Jin, J; Liu, Y; Song, N, 2020) |
| "Keloid is a disease that is difficult to cure and has a high recurrence rate." | 1.56 | [Examining the pathogenesis and therapeutic strategy of keloids from the perspective of systemic inflammation]. ( Cao, ZD; Liu, W, 2020) |
| "Silicone dressings have been used to treat hypertrophic scars and keloids since 1983." | 1.56 | Silicone sheets and new gels to treat hypertrophic scars and keloids: A short review. ( de Oliveira, GV; Gold, MH, 2020) |
| "A keloid is characterized by red, tickling, hard, and irregular raised tissues, and it tends to outgrow its origin." | 1.56 | Resveratrol inhibits proliferation and promotes apoptosis of keloid fibroblasts by targeting HIF-1α. ( Guan, E; Han, Q; Huang, J; Liu, Y; Liu, Z; Long, F; Long, X; Si, L; Wang, X; Zhang, H; Zhang, M; Zhao, R; Zhao, RC, 2020) |
| "Keloid is a fibrous tissue proliferative disease in which proliferative scars grow beyond the boundary of the original wound skin." | 1.56 | Long non-coding RNA CACNA1G-AS1 promotes proliferation and invasion and inhibits apoptosis by regulating expression of miR-205 in human keloid fibroblasts. ( Gao, YK; Jiang, H; Jie, X; Nie, B; Zhao, X, 2020) |
| "Keloids are considered as benign fibroproliferative skin tumors, and rare cases of malignancies have been reported." | 1.56 | Low-Grade Myofibroblastic Sarcoma Arising From Keloid Scar on the Chest Wall After Thoracic Surgery. ( Chen, A; Kuo, YR; Lin, SD; Ramachandran, S; Yang, CK, 2020) |
| "Although keloids have been empirically treated with steroids and radiation, evidence-based radiation parameters for keloid therapy are lacking." | 1.56 | Treatment of keloids with a single dose of low-energy superficial X-ray radiation to prevent recurrence after surgical excision: An in vitro and in vivo study. ( Cohen, GF; Gunjan, A; Om, A; Phillips, EON; Price, KM; Rosenberg, LZ; Shaath, TS; Son, Y; Stefanovic, B; Wolfe, CM, 2020) |
| "Management of keloid is difficult, so there is always a need for adequate and effective therapy." | 1.56 | Comparative evaluation of therapeutic efficacy and safety of intralesional triamcinolone acetonide injection vs intralesional radiofrequency with intralesional triamcinolone acetonide in treatment of keloids. ( Brar, BK; Kaushal, V; Kumar, S; Singh, A, 2020) |
| "Histologic examination of scar tissue punch biopsies (hematoxylin-eosin staining) before and after the treatment was performed as well as magnetic resonance scan with contrast." | 1.56 | Fat Injection for Cases of Severe Burn Outcomes: A New Perspective of Scar Remodeling and Reduction. ( Klinger, M; Marazzi, M; Torre, M; Vigo, D, 2020) |
| "Pilar leiomyoma is the most common subtype originating from arrector pili muscles of pilosebaceous unit." | 1.56 | Cutaneous Leiomyoma Mimicking a Keloid. ( Arık, D; Boyuk, E; Saracoğlu, ZN, 2020) |
| "All patients treated for keloids at the authors' institution were included." | 1.56 | Efficacy of Surgical Excision and Brachytherapy in the Treatment of Keloids: A Retrospective Cohort Study. ( Breton, P; Daurade, M; Ibrahim, B; Lorchel, F; Rouard, N; Sigaux, N, 2020) |
| "Cryotherapy is used to treat keloid scars; however, the molecular and pathological mechanisms are not clearly understood." | 1.56 | Tissue-remodelling M2 Macrophages Recruits Matrix Metallo-proteinase-9 for Cryotherapy-induced Fibrotic Resolution during Keloid Treatment. ( Kim, J; Kim, SM; Lee, JH; Lee, WJ; Lee, YI; Song, SY, 2020) |
| "Autophagy induction by rapamycin treatment in keloid fibroblasts effectively suppressed expression levels of Notch1 and NLRP3 inflammasome proteins." | 1.56 | Contribution of Autophagy-Notch1-Mediated NLRP3 Inflammasome Activation to Chronic Inflammation and Fibrosis in Keloid Fibroblasts. ( Kang, H; Kim, JE; Kim, SK; Lee, DG; Lee, KJ; Lee, S; Lee, YJ; Park, H; Park, SH, 2020) |
| "Median time to recurrence was 23 months, with a slightly higher recurrence rate in AA patients (32%; p = 0." | 1.56 | Pediatric earlobe keloids: Outcomes and patterns of recurrence. ( Drucker, NA; Islam, S; Khan, FA; Larson, SD; Taylor, JA, 2020) |
| "Keloid is a dermal tumor with high recurrence rate." | 1.51 | Connection between T regulatory cell enrichment and collagen deposition in keloid. ( Chen, Y; Fu, X; Jin, Q; Niu, F; Qiao, J, 2019) |
| "Keloid is a major complication of wound healing." | 1.51 | Demographic and clinical characteristics of keloids in an urban center in Sub-Sahara Africa. ( Belie, O; Mofikoya, BO; Ugburo, AO, 2019) |
| "Keloids are hard nodules or plaques formed by excessive proliferation of connective tissue." | 1.51 | A Novel Radiotherapy Approach for Keloids with Intrabeam. ( Fu, J; Li, H; Shao, Y; Sun, Y; Yang, X; Yu, W; Zhang, L; Zhang, X, 2019) |
| "Keloids are a common presenting complaint in Black Africans but remain poorly documented in these populations." | 1.51 | Epidemiology and clinical features of keloids in Black Africans: a nested case-control study from Yaoundé, Cameroon. ( Akpadjan, F; Kouotou, EA; Mendouga Menye, CR; Nansseu, JR; Ndjitoyap Ndam, EC; Omona Guissana, E; Tounkara, TM; Zoung-Kanyi Bissek, AC, 2019) |
| "Keloid is a benign fibroblastic tumor which is most often secondary to a scar, but it can occur spontaneously in a subject with black skin." | 1.51 | [Giant right post-traumatic retroauricular keloid]. ( Mallé, M; Touré, S, 2019) |
| "Keloids are benign skin tumors with a high recurrence rate following surgical excision." | 1.51 | CUDC‑907 reverses pathological phenotype of keloid fibroblasts in vitro and in vivo via dual inhibition of PI3K/Akt/mTOR signaling and HDAC2. ( Gao, Z; Huang, J; Lin, M; Liu, W; Tu, T; Wang, W; Wu, X; Zhang, W; Zhou, G, 2019) |
| "A keloid is defined as an overgrowth of the dense fibrous tissues that form around a wound." | 1.51 | HIF-1α promotes the keloid development through the activation of TGF-β/Smad and TLR4/MyD88/NF-κB pathways. ( Chu, X; Lei, R; Li, J; Li, W; Liu, F; Wang, Y; Xu, J; Zhang, S, 2019) |
| "Keloids are very resistant to treatment in dermatology and plastic surgical practice." | 1.51 | BTXA regulates the epithelial-mesenchymal transition and autophagy of keloid fibroblasts via modulating miR-1587/miR-2392 targeted ZEB2. ( Fan, F; Hou, Z; Liu, P, 2019) |
| "Keloids are a skin disorder where the skin goes beyond the original border of the wound or trauma, resulting in functional and cosmetic deformities, displeasure, itching, pain, psychological stress, and patient dissatisfaction." | 1.51 | Therapeutic effect of interleukin-10 in keloid fibroblasts by suppression of TGF-β/Smad pathway. ( Ge, P; Huang, GB; Shi, CK; Zhao, YP, 2019) |
| "Auricular keloids are common following ear piercing, infection, trauma, burns, or spontaneously, and they are highly resistant for treatment and are followed by severe cosmetic problems, especially for patients with bulky auricular keloids." | 1.51 | Combination therapy for bulky auricular keloids: a clinical experience. ( Jiang, C; Xu, Q; Yang, Y, 2019) |
| "Penile and genital keloids are uncommon despite frequent surgeries in the genital area." | 1.51 | Keloid formation after pediatric male genital surgeries: an uncommon and difficult problem to manage. ( Alyami, F; Ferandez, N; Koyle, MA; Salle, JP, 2019) |
| "Burn scar treatment persists as an unsolved problem, involving thousands of affected patients disfigured for life." | 1.51 | Combined Non-Ablative Laser and Microfat Grafting for Burn Scar Treatment. ( Agaoglu, G; Jawad, MA; Onur Erol, O, 2019) |
| "Keloid is a healing disorder that occurs exclusively in humans." | 1.51 | Keloid negatively affects body image. ( Brito, MJA; Ferreira, LM; Filho, AG; Isoldi, FC; Motoki, THC, 2019) |
| "In this series, the overall recurrence rate was 32%, reported with an average follow-up of 28 months." | 1.51 | Adjuvant Radiotherapy After Keloid Excision: Preliminary Experience in Taiwan. ( Chen, YC; Hsu, CK; Hsueh, WT; Hsueh, YY; Huang, YT; Hung, KS; Ogawa, R, 2019) |
| "Keloids are benign fibroproliferative skin tumors that can cause disfigurement and disability." | 1.51 | Analysis of Keloid Response to 5-Fluorouracil Treatment and Long-Term Prevention of Keloid Recurrence. ( Chong, T; Costa, C; Karimpour-Fard, A; LaRanger, R; Mathes, D; Wright, WE, 2019) |
| "Keloids are a dermal fibrotic disease whose etiology remains totally unknown and for which there is no successful treatment." | 1.51 | Tension enhances cell proliferation and collagen synthesis by upregulating expressions of integrin αvβ3 in human keloid-derived mesenchymal stem cells. ( Cao, T; Liu, T; Lv, Y; Ma, B; Pang, H; Song, H; Wang, W; Zhai, D; Zhang, H; Zhang, Y; Zhou, Z, 2019) |
| "Keloids are a common dermal pathological disorder characterized by the excessive deposition of extracellular matrix components; however, the exact pathogenesis of the disease is still not clear." | 1.51 | Integrated Interaction Network of MicroRNA Target Genes in Keloid Scarring. ( Guo, J; Li, X; Liu, Z; Lu, D; Lu, H; Lyu, L; Zhao, Y, 2019) |
| "Keloids are the most common pathological form of trauma healing, with features that seriously affect appearance and body function, are difficult to treat and have a high recurrence rate." | 1.51 | MicroRNA-152-5p inhibits proliferation and migration and promotes apoptosis by regulating expression of Smad3 in human keloid fibroblasts. ( Lei, R; Pang, Q; Shen, Y; Wang, Y; Xu, J; Xu, M; Xu, S, 2019) |
| "The OSI-027 treatment of keloid keratinocytes showed more effectively inhibited cell proliferation and migration compared to the mTORC1 inhibitor, rapamycin." | 1.51 | Targeting mTORC1/2 with OSI-027 inhibits proliferation and migration of keloid keratinocytes. ( Chen, J; Liu, K; Liu, Y; Wang, X; Zhang, Z, 2019) |
| "Keloids are defined histopathologically as an inflammatory disorder characterized by exhibiting numerous fibroblasts, abnormal vascularization, increased number of proinflammatory immune cells as well as uncontrolled cell proliferation, and exacerbated and disorganized deposition of extracellular matrix (ECM) molecules." | 1.51 | Galectin-1 and Galectin-3 and Their Potential Binding Partners in the Dermal Thickening of Keloid Tissues. ( Arciniegas, E; Carrillo, LM; Chopite, M; Ramírez, R; Rojas, H, 2019) |
| "Helical rim keloids are difficult to excise because of the complex, three-dimensional, cartilaginous structure of the helix and its thin and tightly adherent covering layer of skin." | 1.51 | Chondrocutaneous Bilateral Advancement Flap with Postoperative Radiation Therapy for a Helical Rim Keloid. ( Hayashi, T; Maeda, T; Murao, N; Yamamoto, Y, 2019) |
| "Paclitaxel (PTX) was an effective chemotherapeutic agent and has been reported to have anti-fibrotic effects, but the strong hydrophobicity brings a challenge for its clinical application." | 1.51 | Improving the anti-keloid outcomes through liposomes loading paclitaxel-cholesterol complexes. ( Chen, L; Gao, Z; Huang, W; Jin, M; Jin, Z; Wang, M; Wang, Q, 2019) |
| " A non-linear dose-response of cucurbitacin I, a selective JAK2/STAT3 inhibitor, in collagen type I expression of keloid-derived plasma clot-based skin equivalents implicates a likely role of STAT3 signalling in keloid pathogenesis." | 1.51 | STAT3 signalling pathway is implicated in keloid pathogenesis by preliminary transcriptome and open chromatin analyses. ( Chuong, CM; Kulber, DA; Lee, YS; Liang, YC; Tanabe, K; Tuan, TL; Widelitz, R; Wu, P, 2019) |
| "The incidence of tracheal stenosis is higher in keloid than non-keloid subjects (19." | 1.51 | Iatrogenic subglottic tracheal stenosis after tracheostomy and endotracheal intubation: A cohort observational study of more severity in keloid phenotype. ( Chang, E; Lu, J; Ma, D; Masters, J; Meng, F; Soo, CP; Sun, M; Wu, L; Zhang, J; Zhao, W; Zhou, S, 2019) |
| "Keloids are characterized by excessive proliferation of fibroblasts and invasion of surrounding healthy skin." | 1.51 | Nitric oxide: Is it the culprit for the continued expansion of keloids? ( Chang, CH; Chen, YW; Feng, CH; Hsieh, SC; Huang, SW; Lai, CS; Li, ZY; Yen, JH, 2019) |
| "Keloids are benign fibrous overgrowths that occur as a result of abnormal wound healing following cutaneous injury." | 1.51 | Trichostatin A‑induced miR‑30a‑5p regulates apoptosis and proliferation of keloid fibroblasts via targeting BCL2. ( Chen, H; Chen, S; Gao, X; He, C; Jian, X; Qu, L; Wang, Y; Zhao, Q; Zou, Q, 2019) |
| "Pathological scarring is a result of the hypertrophy of scar tissue during tissue repair following trauma." | 1.51 | Inhibition of USP4 attenuates pathological scarring by downregulation of the TGF‑β/Smad signaling pathway. ( Cao, Z; Jiang, Q; Lai, Z; Long, S; Na, S; Pan, S; Xin, Y; Yan, J; Zhang, J, 2019) |
| "A keloid is a benign fibroproliferative skin tumor that results from abnormal wound healing after injury and tends to grow beyond the boundary of the original wound; the mechanism of keloid formation is still unclear." | 1.51 | MiR-21 Regulates Keloid Formation by Downregulating Smad7 via the TGF-β/Smad Signaling Pathway. ( Cen, Y; Chen, J; Fang, L; Li, Z; Qing, Y; Wu, J, 2019) |
| "Keloids are debilitating skin lesions that develop often as a result of minor skin lesions." | 1.51 | [Keloid treatment : Where do we stand ?] ( Modarressi, A; Petrou, IG; Pittet-Cuénod, B; Rüegg, EM, 2019) |
| "Keloids are composed of stiff tissue, which displays a fibrotic phenotype with relatively low proliferation." | 1.51 | The Interplay of Mechanical Stress, Strain, and Stiffness at the Keloid Periphery Correlates with Increased Caveolin-1/ROCK Signaling and Scar Progression. ( Akaishi, S; Dohi, T; Gurtner, GC; Matsumoto, NN; Ogawa, R; Padmanabhan, J; Terashima, M; Than, PA, 2019) |
| "Keloid is characterized by overactive fibroblasts." | 1.51 | Knockdown of FOXM1 inhibits activation of keloid fibroblasts and extracellular matrix production via inhibition of TGF-β1/Smad pathway. ( Cheng, C; Wang, S; Xu, M; Zeng, W; Zhang, D; Zhang, Y, 2019) |
| "The formation of keloid is associated with accumulation of extracellular matrix (ECM) formed mainly of collagen and fibronectin." | 1.51 | Interleukin-6 serum level and gene polymorphism in keloid patients. ( Abdu Allah, AMK; Essam, M; Farag, AGA; Hagag, MM; Mohammed, KI; Tayel, NR, 2019) |
| "Keloids are pathologic scars, defined as fibroproliferative diseases resulting from abnormal wound responses, which grow beyond the original wound margins." | 1.51 | Multimodal investigation of a keloid scar by combining mechanical tests in vivo with diverse imaging techniques. ( Chambert, J; Chatelain, B; Humbert, P; Jacquet, E; Joly, S; Lihoreau, T; Rolin, G; Sandoz, P, 2019) |
| "Trichostatin A treatment also resulted in cell stiffening and decreased migratory ability in KFs." | 1.48 | Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts. ( Chen, WR; Cheng, CM; Harn, HI; Ho, YT; Hsu, CK; Lee, JY; Lee, YC; Lin, HH; McGrath, JA; Ogawa, R; Shieh, SJ; Tang, MJ; Wang, YK, 2018) |
| "Keloids are mysterious soft-tissue tumors that are characterized by excessive reparative processes composed of collagen-forming fibroblasts and inflammatory cells." | 1.48 | Complete excision of proliferating core in auricular keloids significantly reduces local recurrence: A prospective study. ( Chang, CH; Chong, Y; Kim, CW; Kim, YS; Park, TH, 2018) |
| "Patient cohorts from 3 centers treated with keloid excision followed by 2 × 9 Gy, 3 × 6 Gy, or 2 × 6 Gy high-dose-rate brachytherapy were retrospectively compared regarding recurrence (after at least 12 months' follow-up) and complications (after at least 1 month's follow-up), using logistic regression analyses." | 1.48 | Optimal High-Dose-Rate Brachytherapy Fractionation Scheme After Keloid Excision: A Retrospective Multicenter Comparison of Recurrence Rates and Complications. ( Bijlard, E; Dehnad, H; Harmeling, JX; Meijer, OWM; Mureau, MAM; Niessen, FB; Verduijn, GM, 2018) |
| "Ginsenoside Rg3 (Rg3) has been reported to exert numerous antitumor effects, thus indicating that Rg3 may be a potential therapeutic agent that targets keloids." | 1.48 | Ginsenoside Rg3 inhibits keloid fibroblast proliferation, angiogenesis and collagen synthesis in vitro via the TGF‑β/Smad and ERK signaling pathways. ( Bian, W; Cheng, L; Jin, R; Tang, M; Wang, W; Zhang, L; Zhang, Y, 2018) |
| "Keloids are characterized by abnormal fibrosis, caused by fibroblasts in response to inflammation." | 1.48 | Conditioned Medium Obtained from Amnion-Derived Mesenchymal Stem Cell Culture Prevents Activation of Keloid Fibroblasts. ( Funayama, E; Furukawa, H; Hosono, H; Kawakubo, K; Murao, N; Ohnishi, S; Oyama, A; Sakamoto, N; Sato, C; Yamamoto, Y, 2018) |
| "A 43-year-old man developed an abnormal scar 6 months following excision of a leiomyoma from his left shoulder." | 1.48 | Delayed diagnosis of dermal leiomyosarcoma mimicking keloid scar. ( Clinton, A; Herbert, K; Sleiwah, A, 2018) |
| "Effective treatment of keloids is challenging because the recurrence rate after surgical excision is high." | 1.48 | The Effects of Postoperative Intralesional Corticosteroids in the Prevention of Recurrent Earlobe Keloids: A Multispecialty Retrospective Review. ( Gold, DA; Jacobsen, G; Jones, LR; Ozog, DM; Sheinin, R, 2018) |
| "A keloid is a fibroproliferative disorder occurring in wounds characterized by an exaggerated response to injury." | 1.48 | Human adipose-derived stem cells inhibit bioactivity of keloid fibroblasts. ( Gao, Z; Ma, Y; Wang, X; Yang, J, 2018) |
| "Keloids are benign dermal tumors occurring approximately 20 times more often in individuals of African descent as compared to individuals of European descent." | 1.48 | Gene-based evaluation of low-frequency variation and genetically-predicted gene expression impacting risk of keloid formation. ( Edwards, TL; Hellwege, JN; Russell, SB; Velez Edwards, DR; Williams, SM, 2018) |
| "Keloids are benign skin tumors that develop in individuals who have a positive family history of keloid disorders." | 1.48 | miR-34 modulates apoptotic gene expression in Ingenol mebutate treated keloid fibroblasts. ( De Felice, B; Garbi, C; Manfellotto, F; Nacca, M; Santoriello, M, 2018) |
| "Formation of scars after surgical incisions requires the proper appositions of elements contributing to the scarring process." | 1.48 | Centella asiatica (Centellicum®) facilitates the regular healing of surgical scars in subjects at high risk of keloids. ( Belcaro, G; Cotellese, R; Dugall, M; Feragalli, B; Hosoi, M; Hu, S; Ippolito, E; Ledda, A, 2018) |
| "Generally, the recurrence rate of keloids is unacceptably high after surgical excision alone." | 1.48 | The fortune cookie flap for aesthetic reconstruction after chest keloid resection: a small case series. ( Kim, CW; Lee, JW; Park, TH, 2018) |
| "Lobomycosis or lacaziosis is a chronic granulomatous fungal infection caused by Lacazia loboi." | 1.48 | Lobomycosis: a therapeutic challenge. ( Aguilar, CR; Araújo, MG; Cirilo, NS; Guedes, ACM; Santos, SNMBD, 2018) |
| "Keloid is a fibro-proliferative skin disorder with tumor-like behavior and dependence on anaerobic glycolysis (the Warburg effect), but its exact pathogenesis is unknown." | 1.48 | Upregulation of autophagy and glycolysis markers in keloid hypoxic-zone fibroblasts: Morphological characteristics and implications. ( Eid, N; Ito, Y; Kondo, Y; Okuno, R; Otsuki, Y; Ueda, K, 2018) |
| "Keloids are a type of abnormal scar tissue." | 1.48 | Downregulation of miR‑637 promotes proliferation and metastasis by targeting Smad3 in keloids. ( Chang, P; Guo, B; Hui, Q; Li, W; Tao, K; Zhang, Y, 2018) |
| " The cytotoxicity and bystander effects of Dm‑dNK combined with cytotoxic nucleoside analogs were both observed in Dm‑dNK+ keloid fibroblasts." | 1.48 | Efficacy of lentivirus‑mediated Drosophila melanogaster deoxyribonucleoside kinase combined with (E)‑5‑(2‑bromovinyl)‑2'‑deoxyuridine or 1‑β‑D‑arabinofuranosylthymine therapy in human keloid fibroblasts. ( Gu, M; Jiang, H; Sun, Y; Zheng, X, 2018) |
| "Keloids are skin fibroproliferative tumors characterized by locally invasive growth of fibroblasts and excessive collagen deposition." | 1.48 | Identification of a novel mutation in the mechanoreceptor-encoding gene CXCR1 in patients with keloid. ( Cai, L; Huang, Y; Ke, X; Wang, M; Zhang, Q; Zhao, X, 2018) |
| "Keloids were located on the ear (34%), neck/shoulder (19%), abdomen (13%), chest (10%), face (9%), breast (7%), extremities (4%), and back (3%)." | 1.48 | Dose Effect in Adjuvant Radiation Therapy for the Treatment of Resected Keloids. ( Fontanesi, J; Gresswell, S; Hajjar, RT; Hasan, S; Renz, P; Trombetta, M, 2018) |
| "Because keloid and atopic dermatitis have overlapping pathophysiological mechanisms, we aimed to evaluate keloid risk in patients with atopic dermatitis." | 1.48 | Keloid risk in patients with atopic dermatitis: a nationwide retrospective cohort study in Taiwan. ( Lu, CC; Lu, YY; Wang, QR; Wu, CH; Yu, WW; Zhang, CL; Zhang, L, 2018) |
| "Keloid is a common abnormal cutaneous fibroproliferative disorder." | 1.48 | Identification and integrated analysis of microRNA expression profiles in keloid. ( Bian, L; Jin, H; Liu, Z; Lu, D; Lyu, J; Lyu, L; Zhong, L, 2018) |
| "To investigate the effectiveness of internal mammary artery perforator (IMAP) propeller flap repair combined with radiotherapy for chest keloid in female patients." | 1.48 | [Effectiveness of internal mammary artery perforator propeller flap repair combined with radiotherapy for chest keloid in female patients]. ( Cao, C; Chen, Y; Liu, X; Liu, Y; Wu, J; Xiao, H; Xu, X; Yao, B, 2018) |
| "Keloids are defined as highly inflamed, hyperproliferative pathological scars." | 1.48 | High in situ mRNA levels of IL-22, TFG-β, and ARG-1 in keloid scars. ( da Cunha Colombo Tiveron, LR; da Silva, IR; da Silva, MV; Peixoto, AB; Rodrigues, DBR; Rodrigues, V, 2018) |
| "Few reports have described epidermal cysts (ECs) arising from scar tissues, and the standard course of treatment has not been established." | 1.48 | Management of epidermal cysts arising from scar tissues: A retrospective clinical study. ( Kim, CG; Kim, H; Kim, KN; Koh, IC; Lee, HW; Song, JS, 2018) |
| "Keloids are a fibroproliferative disorder of the skin resulted from abnormal healing of injured or irritated skin and are characterized by the ability to spread beyond the original boundary of the wound." | 1.48 | Gallic acid inhibits fibroblast growth and migration in keloids through the AKT/ERK signaling pathway. ( Gao, Z; Liu, K; Ruan, M; Wang, X; Yang, J, 2018) |
| "Keloid is a fibrous benign tumor of the skin caused by increased fibroblast proliferation and overproduction of extracellular matrix (ECM) in the dermis." | 1.48 | MiR-203 regulates keloid fibroblast proliferation, invasion, and extracellular matrix expression by targeting EGR1 and FGF2. ( Peng, W; Qiu, X; Shi, K; Yan, D; Zheng, W, 2018) |
| "Keloid is characterized by excessive proliferation of scar tissue following trauma." | 1.48 | Detection and Analysis of the Hedgehog Signaling Pathway-Related Long Non-Coding RNA (lncRNA) Expression Profiles in Keloid. ( Fu, S; Huang, H; Liu, D, 2018) |
| " Our work was aim to prepare N-(4-hydroxyphenyl) retinamide-loaded lipid microbubbles (4HPR-LM) combined with ultrasound for anti-keloid therapy." | 1.48 | Lipid nano-bubble combined with ultrasound for anti-keloids therapy. ( Gao, Z; Jin, HY; Jin, ZH; Li, ZN; Wang, QM; Wang, XQ, 2018) |
| "Hypocrellin B (HB) is a natural perylene quinone photosensitizer." | 1.46 | Effects of Photodynamic Therapy Using Yellow LED-light with Concomitant Hypocrellin B on Apoptotic Signaling in Keloid Fibroblasts. ( Han, G; Hu, Y; Jiao, Y; Li, S; Qi, T; Wei, G; Zhang, C, 2017) |
| " Radiation protocol consisted of 1 to 3 fractions, with cumulative dosage ranging from 1,300 to 1,800 cGy." | 1.46 | Advancing Keloid Treatment: A Novel Multimodal Approach to Ear Keloids. ( Adenegan, R; Ganzer, CA; Jones, ME; Lee, J; McLane, J, 2017) |
| "Keloid is a benign fibroproliferative growths resulting from an overexuberant healing response." | 1.46 | FDG-Avid Keloid on PET/CT Imaging. ( Li, ZG, 2017) |
| "Keloids are benign dermal fibroproliferative tumors that develop as a result of several dysregulated processes." | 1.46 | miR-141-3p inhibits fibroblast proliferation and migration by targeting GAB1 in keloids. ( Cui, F; Feng, J; Pang, Q; Rang, Z; Xue, S, 2017) |
| "The radioactive patch treatment of keloids is noninvasive, painless and safe with prolonged outcome." | 1.46 | Noninvasive treatment of keloid using customized Re-188 skin patch. ( Bhusari, P; Chhabra, A; De, D; Handa, S; Kumar, M; Kumaran, S; Mittal, BR; Palarwar, K; Rathore, Y; Shukla, J; Vatsa, R, 2017) |
| "Keloids are characterized by excessive collagen deposition and growth beyond the edges of the initial injury, and cytokines may be related to their formation." | 1.46 | In Situ Cytokine Expression and Morphometric Evaluation of Total Collagen and Collagens Type I and Type III in Keloid Scars. ( Carneiro, CAX; da Silva, IR; da Silva, MV; Dos Reis, MA; Furtado, PC; Peixoto, AB; Rodrigues, BR; Rodrigues, DBR; Rodrigues, V; Tiveron, LCRDC, 2017) |
| "Keloid is a disorder of fibroproliferative diseases that occurs in wounds, characterized by an exaggerated response to injury." | 1.46 | Downregulation of β-catenin blocks fibrosis via Wnt2 signaling in human keloid fibroblasts. ( Cai, Y; Pan, M; Wang, C; Wu, W; Yang, W; Zhu, S, 2017) |
| "Keloid is one kind of benign skin disease caused by hyperplasia of fibroblasts and collagen fibrils." | 1.46 | Inhibiting function of human fetal dermal mesenchymal stem cells on bioactivities of keloid fibroblasts. ( Gong, H; Jiang, D; Jiao, Y; Qi, Y; Wang, X; Zhang, J, 2017) |
| "Keloids are abnormal fibroproliferative scars that pose a significant challenge to patients and clinicians." | 1.46 | Abnormal expression of the vitamin D receptor in keloid scars. ( Hahn, JM; Supp, DM, 2017) |
| "Keloids are benign cutaneous lesions, arising from proliferating fibroblasts." | 1.46 | Treatment of ear keloids: algorithm for a multimodal therapy regimen. ( Hoffmann, TK; Rotter, N; Scheithauer, MO; Thierauf, J; Veit, JA; Walther, M, 2017) |
| "The etiology of keloids has not been resolved but previous studies suggest that keloids are a genetically heterogeneous disorder." | 1.46 | Identification of ASAH1 as a susceptibility gene for familial keloids. ( Ademola, S; Bamshad, MJ; Benahmed-Miniuk, F; Fadiora, S; Hu, Y; Kanaujiya, JK; Leal, SM; Nickerson, DA; Odesina, V; Olaitan, PB; Oluwatosin, OM; Reichenberger, EJ; Santos-Cortez, RLP; Sun, F; Tao, J, 2017) |
| "Keloids are fibrous growths that occur as a result of abnormal response to dermal injury." | 1.46 | Successful Treatment of Keloid With Fractionated Carbon Dioxide (CO2) Laser and Laser-Assisted Drug Delivery of Triamcinolone Acetonide Ointment in an African-American Man. ( Ho, D; Jagdeo, J; Kraeva, E, 2017) |
| "Keloid is characterized by hyper-proliferation of fibroblasts and excess extracellular matrix (ECM) deposition." | 1.46 | TMEM88 inhibits extracellular matrix expression in keloid fibroblasts. ( Cui, S; Lu, F; Si, E; Wang, W; Yuan, Z; Zhang, X; Zhao, H, 2017) |
| "Keloids are reportedly rare at the extremes of life." | 1.46 | Pediatric keloids: A 6-year retrospective review. ( Adebayo, W; Ademola, SA; Iyun, AO; Michael, AI; Olawoye, OA; Oluwatosin, OM, 2017) |
| "Keloid is a cutaneous fibroproliferative disorder." | 1.46 | Endothelial dysfunction may promote keloid growth. ( Kubota, Y; Noishiki, C; Ogawa, R; Takagi, G, 2017) |
| "The toe keloids were effectively cured by surgical excision and skin flap transplantation combined with postoperative irradiation and hyperbaric oxygen (HBO) treatment." | 1.46 | Toe keloid after nail extraction treated with surgical excision: A case report. ( Dong, X; Liu, H; Liu, S; Song, K; Wang, Y; Zhang, M, 2017) |
| "Keloid and hypertrophic scars represent an aberrant response to the wound healing process." | 1.46 | Keloids and Hypertrophic Scars: Pathophysiology, Classification, and Treatment. ( Berman, B; Maderal, A; Raphael, B, 2017) |
| "Involucrin was restricted to the granular layer in healthy skin, but showed panepidermal expression in keloids." | 1.46 | Increased epidermal thickness and abnormal epidermal differentiation in keloid scars. ( Everts, V; Gibbs, S; Limandjaja, GC; Monstrey, S; Niessen, FB; Scheper, RJ; van den Broek, LJ; van Veen, HA; Waaijman, T, 2017) |
| "Patient and keloid recurrence data were analyzed using mixed effect Cox regression modeling with a statistical threshold of P < ." | 1.46 | Surgical Excision and Adjuvant Brachytherapy vs External Beam Radiation for the Effective Treatment of Keloids: 10-Year Institutional Retrospective Analysis. ( Hoang, D; Kulber, DA; Li, Q; Mirhadi, A; Orgel, M; Reznik, R, 2017) |
| "Keloid is one of the most frustrating problems related to wounding healing and presents a great challenge in clinic." | 1.46 | Upregulation of microRNA-205 suppresses vascular endothelial growth factor expression-mediated PI3K/Akt signaling transduction in human keloid fibroblasts. ( An, G; Liang, S; Liu, Y; Sheng, C; Yao, W, 2017) |
| "Management of keloids has remained a conundrum, because an optimum treatment regimen has yet to be elucidated." | 1.46 | Treatment of Keloids With Excision and Adjuvant Radiation: A Single Center Experience and Review of the Literature. ( Bennett, KG; Brown, DL; Hayman, JA; Kung, TA, 2017) |
| "Keloid is a benign tumor that is characterized by the hyperproliferation of dermal fibroblasts and excessive deposition of extracellular matrix (ECM) especially the collagen." | 1.46 | Inhibition of collagen synthesis by IWR-1 in normal and keloid-derived skin fibroblasts. ( Jiang, RH; Kim, CD; Lee, JH; Yin, WT; Yoon, TJ; Zhou, MW; Zhu, MJ, 2017) |
| "Keloids are pathologic scars defined as dermal fibrotic tumors resulting from a disturbance of skin wound healing process." | 1.46 | 3D modeling of keloid scars in vitro by cell and tissue engineering. ( Binda, D; Humbert, P; Mankhetkorn, S; Pazart, L; Rolin, G; Suttho, D, 2017) |
| "Keloids are benign fibroproliferative tumors more frequently found among African Americans." | 1.46 | Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans. ( Bonifacio, KM; Cruz, T; Fuentes-Duculan, J; Garcet, S; Gilleadeau, P; Krueger, JG; Kunjravia, N; Suárez-Fariñas, M; Sullivan-Whalen, M; Tirgan, MH; Wang, CQF; Xu, H, 2017) |
| "Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal progression and post-surgical recurrence and histologically by the accumulation of collagen and fibroblast ingredients." | 1.46 | Keloid progression: a stiffness gap hypothesis. ( Du, Y; Huang, C; Liu, L; Ogawa, R; Wang, B; You, Z, 2017) |
| "The formation of hypertrophic scaring (HSc) is an abnormal wound-healing response." | 1.46 | A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study. ( Chuang, SS; Hsiao, YC; Yang, JY; Yang, SY, 2017) |
| "Keloids and hypertrophic scars are characterized by excessive proliferation of fibroblasts; abnormal accumulation of extracellular matrix; and clinical findings of raised, red, itchy, and painful lesions." | 1.46 | β-Adrenergic Receptor Blockers Reduce the Occurrence of Keloids and Hypertrophic Scars after Cardiac Device Implantation: A Single-Institution Case-Control Study. ( Aya, R; Doi, T; Enoshiri, T; Katayama, Y; Kawaguchi, A; Kawaji, T; Naitoh, M; Noda, K; Suzuki, S; Yamawaki, S, 2017) |
| " Few reports describe the adverse effects and complications of VNS." | 1.46 | Adverse Effects and Surgical Complications in Pediatric Patients Undergoing Vagal Nerve Stimulation for Drug-Resistant Epilepsy. ( Fiori, L; Giussani, C; Grioni, D; Landi, A; Pirillo, D; Sganzerla, EP; Trezza, A, 2017) |
| "Keloids are fibroproliferative diseases characterized by the accumulation of an extracellular matrix including collagen." | 1.46 | Sulforaphane suppresses cell growth and collagen expression of keloid fibroblasts. ( Horinaka, M; Kawarazaki, A; Nishino, K; Numajiri, T; Sakai, T; Yasuda, S, 2017) |
| "After treatment, the mean keloid VSS score was decreased on both sides (4." | 1.46 | Laser-assisted topical corticosteroid delivery for the treatment of keloids. ( Chun, JY; Lee, JH; Park, JH, 2017) |
| "Keloid is a pathologic fibro-proliferative disorder and is characterized by hyper-proliferation of fibroblasts and excess extracellular matrix (ECM) deposition." | 1.46 | Knockdown of IRF3 inhibits extracellular matrix expression in keloid fibroblasts. ( Li, ZM; Lin, XH; Zhang, L; Zhang, QY; Zhang, Y, 2017) |
| "Keloids were considered active when CDU detected vascularity within the lesion." | 1.46 | Color Doppler Ultrasound Assessment of Activity in Keloids. ( Alonso, F; Lobos, N; Valenzuela, F; Wortsman, X, 2017) |
| "Keloids were biopsied before starting cryosurgery and after two treatment sessions for the immunohistochemical evaluation of TGF-β1 expression." | 1.46 | Suppression of transforming growth factor-beta1 expression in keloids after cryosurgery. ( Awad, SM; Ismail, SA; Makboul, R; Refaiy, AE; Sayed, DS, 2017) |
| "Radiation therapy is considered to be a treatment for keloid scarring; however, radioresistance has been shown to be a serious impediment to treatment efficacy." | 1.43 | 2ME2 increase radiation-induced apoptosis of keloid fibroblasts by targeting HIF-1α in vitro. ( Long, F; Long, X; Si, L; Wang, X; Yang, B; Zhang, F, 2016) |
| "Verapamil has shown a great potential in the management of keloid and hypertrophic scars." | 1.43 | Role of verapamil in preventing and treating hypertrophic scars and keloids. ( Cen, Y; Chen, J; Li, Z; Mao, Y; Wang, R; Zhang, Z, 2016) |
| "Keloids are considered benign dermal fibroproliferative tumors." | 1.43 | Tanshinone IIA Inhibits Proliferation and Induces Apoptosis Through the Downregulation of Survivin in Keloid Fibroblasts. ( Chen, G; Li, Q; Liang, X; Liang, Y; Liu, D, 2016) |
| "Keloids are marked by an overabundance of extracellular matrix." | 1.43 | Hepatocyte growth factor-expressing adenovirus upregulates matrix metalloproteinase-1 expression in keloid fibroblasts. ( Ahn, HM; Choi, IK; Jeon, YR; Lee, WJ; Lew, DH; Rah, DK; Yun, CO, 2016) |
| "Leptin has been recognized as an important factor for promoting normal cutaneous wound healing." | 1.43 | Immunohistochemical Evaluation of Leptin Expression in Wound Healing: A Clue to Exuberant Scar Formation. ( Bakry, OA; Samaka, RM; Seleit, I; Tawfik, AS, 2016) |
| "To compare any differences of recurrence rate between categorical variables (the presence/absence of foreign body reactions), Fisher's exact tests were used." | 1.43 | Foreign body reactions may not influence the keloid recurrence. ( Lee, B; Park, JH; Park, TH; Rah, DK, 2016) |
| "Keloids are progressively expanding scars, mostly prevalent in individuals of African descent." | 1.43 | The role of aldo-keto reductase 1C3 (AKR1C3)-mediated prostaglandin D2 (PGD2) metabolism in keloids. ( Frazier, R; Katdare, M; Mantel, A; Newsome, A; Thekkudan, T, 2016) |
| "Keloids are wounding-induced tumor-like human scars." | 1.43 | Keloid-derived, plasma/fibrin-based skin equivalents generate de novo dermal and epidermal pathology of keloid fibrosis in a mouse model. ( Benya, PD; Chiu, WC; Choi, A; Hsu, T; Kim, EW; Kulber, DA; Lee, YS; Sarkozy, H; Tuan, TL, 2016) |
| "Twenty-one patients with 61 untreated keloids were enrolled into this study." | 1.43 | Increased blood flow in keloids and adjacent skin revealed by laser speckle contrast imaging. ( Chen, B; Jia, Y; Liu, Q; Long, X; Wang, X; Wang, Y; Yu, N, 2016) |
| "Scar pruritus is frequently encountered in clinical practice (particularly in burn patients) owing to its poorly known pathogenesis and difficult treatment." | 1.43 | Solanidine and tomatidine trigger scar pruritus. ( Alonso, PE; Rioja, LF, 2016) |
| "Keloids are scars that grow beyond the boundaries of a cutaneous injury, inflammation, surgical incision, or burn." | 1.43 | A New Approach in the Treatment of Keloids: UVA-1 Laser. ( Kaya, H; Polat, M; Şahin, A, 2016) |
| "Five patients underwent treatment; two had keloids involving the superior helix of the ear (average area, 2." | 1.43 | A Novel Approach to Keloid Reconstruction with Bilaminar Dermal Substitute and Epidermal Skin Grafting. ( Bastidas, N; Kasabian, AK; Nguyen, KT; Shikowitz, L, 2016) |
| "Sorafenib is a promising agent for the treatment of keloids and hypertrophic scars." | 1.43 | Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways. ( Chen, YL; Ding, X; Gao, Z; Gu, T; Liu, W; Qu, M; Wang, W; Wu, X; Xu, L; Zhang, W, 2016) |
| "Keloid is an abnormal hyperproliferative scarring process with involvement of complex genetic and triggering environmental factors." | 1.43 | Pleiotrophin is downregulated in human keloids. ( Cho, S; Jin, CL; Kim, JE; Kim, M; Kim, Y; Lee, DH; Lee, MJ; Shin, MH, 2016) |
| "It is difficult to find an ideal treatment for keloids in this area due to the limit of local soft tissues and higher recurrence rate." | 1.43 | Algorithm of chest wall keloid treatment. ( Long, X; Wang, X; Wang, Y; Zhang, M; Zhao, R, 2016) |
| "Keloid is the abnormal wound healing puzzled by the aggressive growth and high recurrence rate due to its unrevealed key pathogenic mechanism." | 1.43 | MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes. ( Cao, R; Jiao, H; Liu, Y; Lv, X; Pan, B; Sun, X; Wang, L; Xiao, R; Yan, L; Zhuang, Q, 2016) |
| "Keloid is a benign fibrous growth, which presents in scar tissue of predisposed individuals." | 1.43 | Risk factors of keloids in Syrians. ( Kesh, F; Khaddam, J; Shaheen, A, 2016) |
| "The color of 33 untreated keloids from 30 patients was measured with a narrow-band reflectance colorimeter." | 1.43 | Objective Spectrometric Measurement of Keloid Color in the East Asian Population: Pitfalls of Subjective Color Measurements. ( Akaishi, S; Aoki, M; Dohi, T; Hyakusoku, H; Nakao, J; Ogawa, R, 2016) |
| "The recurrence is common after surgical excision, and the lesion can be exacerbated by surgery." | 1.43 | Corneal keloid: four case reports of clinicopathological features and surgical outcome. ( Choi, HJ; Kim, MK; Lee, HK; Oh, JY; Wee, WR, 2016) |
| "Keloids are fibroproliferative scars that develop as a result of a dysregulated wound healing process; however, the molecular mechanisms of keloid pathogenesis remain unclear." | 1.43 | Growth Differentiation Factor-9 Promotes Fibroblast Proliferation and Migration in Keloids through the Smad2/3 Pathway. ( Gao, Z; Jiang, Z; Wang, X; Wu, X; Xia, L; Yu, Q; Zhang, Y, 2016) |
| "Keloids are fibrous overgrowths induced by cutaneous injury." | 1.43 | MiR-181a Targets PHLPP2 to Augment AKT Signaling and Regulate Proliferation and Apoptosis in Human Keloid Fibroblasts. ( Cui, F; Pang, QY; Rang, Z; Wang, YW; Wang, ZY; Yang, G, 2016) |
| "At present, keloids are classified as strongly inflammatory scars, while hypertrophic scars are considered to be mildly inflammatory scars." | 1.43 | Endothelial dysfunction may play a key role in keloid and hypertrophic scar pathogenesis - Keloids and hypertrophic scars may be vascular disorders. ( Akaishi, S; Ogawa, R, 2016) |
| "The literature on keloids is replete with authors expressing frustration with treatment results." | 1.43 | Strategy for Successful Management of Facial Keloid Using Triamcinolone Injection as Adjunct to Surgery. ( Aluko-Olokun, B; Olaitan, AA, 2016) |
| "There is strong evidence of genetic susceptibility in individuals with keloid disorder." | 1.42 | Clinical implications of single- versus multiple-site keloid disorder: a retrospective study in an Asian population. ( Chang, CH; Halim, AS; Park, JH; Park, TH; Tirgan, MH, 2015) |
| "Keloids are benign fibro-proliferative skin lesions that very rarely occur on the soles." | 1.42 | Plantar keloids: diagnostic and therapeutic issues in six patients. ( Bagot, M; Battistella, M; Cavelier-Balloy, B; Duron, JB; Gorj, M; Hickman, G; Masson, V; May, P; Petit, A; Schneider, P; Vanhaecke, C; Vilmer, C, 2015) |
| "Keloids are fibroproliferative dermal lesions characterized by the proliferation of fibroblasts." | 1.42 | The ultraviolet A-activated photosensitizer 2-(4-aminophenyl)-7-methoxybenzothiazole suppresses proliferation and induces apoptosis of keloid fibroblasts: a potential adjunctive therapy for keloids. ( Fang, AH; Hu, WP; Kuo, HY; Tien, LY; Wang, JJ; Wu, CS, 2015) |
| "Keloids are one of the common refractory conditions in dermatology and aesthetic plastic surgery." | 1.42 | Ionizing irradiation inhibits keloid fibroblast cell proliferation and induces premature cellular senescence. ( Cao, JP; Huan, J; Ji, J; Ji, SJ; Tian, Y; Zhang, LY; Zhou, XZ; Zhu, YQ, 2015) |
| "Cryosurgery is a safe and effective treatment of keloids." | 1.42 | Intralesional vs. contact cryosurgery in treatment of keloids: a clinical and immunohistochemical study. ( Abdel-Meguid, AM; Awad, SM; Refaiy, AE; Sayed, DS; Weshahy, AH, 2015) |
| "Keloids are benign hyper-proliferative growths of fibrous tissue where increased fibroblast activity results in abnormal collagen deposition." | 1.42 | Premature collagen fibril formation, fibroblast-mast cell interactions and mast cell-mediated phagocytosis of collagen in keloids. ( Arbi, S; Bester, MJ; Eksteen, EC; Oberholzer, HM; Taute, H, 2015) |
| "Glucocorticoids (GCs) are first-line treatment for keloid disease (KD) but are limited by high incidence of resistance, recurrence and undesirable side-effects." | 1.42 | An abnormality in glucocorticoid receptor expression differentiates steroid responders from nonresponders in keloid disease. ( Bayat, A; Matthews, LC; McGrouther, DA; Ray, DW; Rutkowski, D; Syed, F; Watson, RE, 2015) |
| "The untreated cultured keloid fibroblasts served as controls." | 1.42 | The effect of 595 nm pulsed dye laser on connective tissue growth factor (CTGF) expression in cultured keloid fibroblasts. ( Avram, MM; Guan, M; Huang, G; Lu, Z; Ma, Y; Yang, Q; Yue, B; Zhu, R, 2015) |
| "Keloids are a pathologic condition of the reparative process, which present as excessive scar formation that involves various cells and cytokines." | 1.42 | Histomorphometric analysis of collagen architecture of auricular keloids in an Asian population. ( Chang, CH; Chong, Y; Park, TH; Seo, Sw, 2015) |
| "Keloids and hypertrophic scars are prevalent and psychologically distressful dermatologic conditions." | 1.42 | Efficacy of IPL device combined with intralesional corticosteroid injection for the treatment of keloids and hypertrophic scars with regards to the recovery of skin barrier function: A pilot study. ( Cho, S; Kim, DY; Park, HS; Yoon, HS, 2015) |
| "Physiological scars were established as a baseline for further comparison between groups." | 1.42 | The dermatology life quality index as a means to assess life quality in patients with different scar types. ( Epple, A; Gauglitz, GG; Poetschke, J; Reinholz, M; Ruzicka, T; Schwaiger, H, 2015) |
| "None of therapeutic options for the treatment of keloids has been found completely effective and satisfactory." | 1.42 | Combination of radiofrequency and intralesional steroids in the treatment of keloids: a pilot study. ( Abdel Hay, RM; El Hawary, MS; Nour-Edin, F; Sayed, K; Weshay, AH, 2015) |
| "Keloid is an overgrowth of scar tissue that develops around a wound." | 1.42 | Aspidin PB, a novel natural anti-fibrotic compound, inhibited fibrogenesis in TGF-β1-stimulated keloid fibroblasts via PI-3K/Akt and Smad signaling pathways. ( Li, G; Li, S; Song, R, 2015) |
| "Keloids are benign fibroproliferative tumors of the skin which commonly occur after injury mainly in darker skinned patients." | 1.42 | Genome-Wide Scan for Methylation Profiles in Keloids. ( Chen, KM; Datta, I; Divine, G; Jones, LR; Ozog, D; Worsham, MJ; Young, W, 2015) |
| "Of these patients, 88." | 1.42 | Location of Keloids and Its Treatment Modality May Influence the Keloid Recurrence in Children. ( Chang, CH; Park, TH, 2015) |
| "The 17-AAG-treated keloid fibroblasts showed significantly decreased proliferation, promotion of apoptosis, and decreased expression of Akt." | 1.42 | Heat Shock Protein 90 Inhibitor (17-AAG) Induces Apoptosis and Decreases Cell Migration/Motility of Keloid Fibroblasts. ( Lee, MH; Lee, WJ; Lew, DH; Park, JC; Rah, DK; Yun, IS, 2015) |
| "Effective treatment of keloid scars is important because patients are often confronted with major cosmetic, psychological, and social consequences." | 1.42 | A simplified three-dimensional volume measurement technique in keloid scars: Validity and reliability. ( Colla, C; Erends, M; Piatkowski de Grzymala, AA; Van den Kerckhove, E; van der Aa, T; van der Hulst, RR; Verhiel, SH, 2015) |
| "Keloid is a fibrotic skin disease for which immune cell infiltration is a primary pathological hallmark." | 1.42 | Analysis of Characteristics Similar to Autoimmune Disease in Keloid Patients. ( Cai, J; Dong, P; Fan, J; Gan, C; Jiao, H; Pan, B; Xiao, R; Yan, L; Zong, X, 2015) |
| "In addition, in 17-AAG-treated keloid spheroids, the collagen deposition and expression of major extracellular matrix proteins were investigated by means of Masson trichrome staining and immunohistochemistry." | 1.42 | Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model. ( Ahn, HM; Kim, YO; Lee, JH; Lee, WJ; Lew, DH; Song, SY; Yun, CO, 2015) |
| "Currently, the treatment of keloids remains a challenge for high recurrence rates." | 1.42 | Ingenol mebutate treatment in keloids. ( Boccia, L; De Felice, B; Guida, M; Nacca, M, 2015) |
| "Keloid is a type of pathological skin scar." | 1.42 | LncRNA expression profiles and validation in keloid and normal skin tissue. ( Liang, X; Long, X; Ma, L; Wang, X, 2015) |
| "Since keloids are a dysfunction of collagen fiber synthesis and organization, this study aimed to evaluate if a 1,210 nm diode laser could have effects in a new animal model of keloid scars." | 1.42 | Treatment of keloid scars with a 1210-nm diode laser in an animal model. ( Andrac-Meyer, L; Bertrand, B; Casanova, D; Kerfant, N; Magalon, G; Mordon, S; Philandrianos, C, 2015) |
| "Recurrence was defined as any elevation of the scar or extension beyond the original surgical field." | 1.42 | Do Histopathologic Parameters Affect the Rate of Recurrence in Auricular Keloid Patients? ( Lee, B; Park, JH; Park, TH, 2015) |
| "His keloids were treated with intralesional corticosteroids with some improvement." | 1.42 | Extensive keloid formation after pemphigus vulgaris. ( Sako, EY; Workwick, S, 2015) |
| "Keloids are defined as overgrowths of scar tissue resulting from abnormal wound healing." | 1.40 | siRNA knockdown of tissue inhibitor of metalloproteinase-1 in keloid fibroblasts leads to degradation of collagen type I. ( Akaishi, S; Aoki, M; Dohi, T; Hyakusoku, H; Miyake, K; Ogawa, R; Shimada, T, 2014) |
| "In the prevention and treatment of keloids and hypertrophic scars, ointments containing heparin and onion extract are very popular." | 1.40 | Effect of enoxaparin and onion extract on human skin fibroblast cell line - therapeutic implications for the treatment of keloids. ( Krauze-Baranowska, M; Pikuła, M; Pobłocka-Olech, L; Sznitowska, M; Trzonkowski, P; Żebrowska, ME, 2014) |
| "All patients referred for treatment of an ear keloid and undergoing subsequent surgical excision followed by immediate freezing of the postoperative wound using cryosurgery were included." | 1.40 | Treatment of earlobe keloids by surgical excision and cryosurgery. ( Boullie, MC; De Barros, A; Dehesdin, D; Joly, P; Litrowski, N, 2014) |
| "Keloids are scars that extend beyond the borders of the original wound." | 1.40 | A keloid edge precut, preradiotherapy method in large keloid skin graft treatment. ( Li, W; Liu, Z; Wang, X; Wang, Y, 2014) |
| "On Days 3, 6, and 9 treated keloid cells showed linear decreases in cell proliferation (BrdU), increases in Annexin V-FITC and TUNEL-positive cells, interruptions of the cell cycle and inhibition of migration in scratch-wound assays." | 1.40 | Human keloid cell characterization and inhibition of growth with human Wharton's jelly stem cell extracts. ( Biswas, A; Bongso, A; Choolani, M; Fong, CY; Srinivasan, A; Subramanian, A, 2014) |
| "Keloid is induced by a pathological wound healing response, and hepatocyte growth factor (HGF) is known to be involved in tissue repair via the activation of its primary receptor, c-Met." | 1.40 | Increased c-Met phosphorylation is related to keloid pathogenesis: implications for the biological behaviour of keloid fibroblasts. ( Jin, Z, 2014) |
| "Keloids are slow growing neoplasms characterized by benign proliferation of fibroblasts that is due, at least in part, to altered cytokine profiles." | 1.40 | Hematopoietic stem cells: do they have a role in keloid pathogenesis? ( Bakry, OA; Basha, MA; El Meadawy, I; Samaka, RM; Tharwat, A, 2014) |
| "The WJ-MSC-CM-treated keloid fibroblasts showed higher proliferation rates than their control keloid fibroblasts with no significant change in apoptosis rate or migration ability." | 1.40 | Effect of human Wharton's jelly mesenchymal stem cell paracrine signaling on keloid fibroblasts. ( Al-Shehab, M; Amini-Nik, S; Arno, AI; Belo, C; Blit, PH; Herer, E; Jeschke, MG, 2014) |
| "Keloid is an inflammatory and fibrotic disease with an unknown pathogenesis." | 1.40 | Treg-enriched CD4+ T cells attenuate collagen synthesis in keloid fibroblasts. ( Funayama, E; Furukawa, H; Hayashi, T; Ikeda, M; Murao, N; Oyama, A; Seino, K; Yamamoto, Y, 2014) |
| "Keloids are locally exuberant dermal scars characterized by excessive fibroblast proliferation and matrix accumulation." | 1.40 | Effect of collagen nanotopography on keloid fibroblast proliferation and matrix synthesis: implications for dermal wound healing. ( Desai, T; Martin, G; Muthusubramaniam, L; Paukshto, M; Zaitseva, T, 2014) |
| "The link between FOXO1 and scarring extends to patients, in particular keloid scars, where we see FOXO1 expression markedly increased in fibroblasts and inflammatory cells within the otherwise normal dermis." | 1.40 | Reduced FOXO1 expression accelerates skin wound healing and attenuates scarring. ( de Kerckhove, M; Hirano, A; Ikematsu, K; Kashiyama, K; Kawata, T; Kim, S; Komatsu, T; Martin, P; Mori, R; Okamoto, M; Park, S; Shimokawa, I; Tanaka, K, 2014) |
| " Twenty-five lesions were treated with intralesional cryotherapy combined with postoperative silicone gel sheeting (the cryotherapy + silicone group), and 7 keloids were treated with intralesional cryotherapy alone (the cryotherapy group)." | 1.40 | Intralesional cryosurgery combined with topical silicone gel sheeting for the treatment of refractory keloids. ( Babic, D; Dunda, S; Eppstein, RJ; Har-Shai, Y; Pallua, N; Stromps, JP, 2014) |
| "Keloids is a fibroproliferative disease." | 1.40 | Keloid incidence in Asian people and its comorbidity with other fibrosis-related diseases: a nationwide population-based study. ( Lee, YC; Sun, LM; Wang, KH, 2014) |
| "A total of 10 patients with 14 keloid scars resistant to conventional treatments were enrolled in a retrospective study between October 2007 and October 2013." | 1.40 | Intralesional cryosurgery to treat keloid scars: results from a retrospective study. ( Bénateau, H; Chopinaud, M; Dompmartin, A; Gourio, C; Labbé, D; Pham, AD; Verneuil, L, 2014) |
| "Keloids are benign dermal tumors that occur ~20 times more often in African versus Caucasian descent individuals." | 1.40 | Admixture mapping identifies a locus at 15q21.2-22.3 associated with keloid formation in African Americans. ( Edwards, TL; Russell, SB; Tsosie, KS; Velez Edwards, DR; Williams, SM, 2014) |
| "A keloid is pathological scar caused by aberrant response to skin injuries, characterized by excessive accumulation of histological extracellular matrix, and occurs in genetically susceptible individuals." | 1.40 | Association of the plasminogen activator inhibitor-1 (PAI-1) Gene -675 4G/5G and -844 A/G promoter polymorphism with risk of keloid in a Chinese Han population. ( Long, J; Sun, Y; Wang, X; Wang, Y, 2014) |
| "A keloid is considered to be a type of benign tumor." | 1.40 | MicroRNA-21 affects proliferation and apoptosis by regulating expression of PTEN in human keloid fibroblasts. ( Chen, X; Liu, Y; Wang, X; Xiao, Z; Yang, D, 2014) |
| "The use of subcutaneous super-tension-reduction suture after chest keloids excision can greatly decrease tension on the dermis and the subcutaneous tissue and can, in combination with postoperative electron-beam irradiation, decrease the rate of relapse." | 1.40 | Forty-five cases of chest keloids treated with subcutaneous super-tension-reduction suture combined with postoperative electron-beam irradiation. ( Chen, B; Ding, JP; Wang, LZ; Yang, MY, 2014) |
| "Keloid is a protruding hypertrophic fibrous formation of the dermis." | 1.40 | [Diagnosis and evolution of a keloid]. ( Hermanns-Lê, T; Nizet, JL; Piérard, GE; Piérard-Franchimont, C, 2014) |
| "Keloids are a proliferative fibrotic disease characterized by abnormal accumulation of extracellular matrix in the dermis." | 1.39 | Chondroitinase injection improves keloid pathology by reorganizing the extracellular matrix with regenerated elastic fibers. ( Fujita, H; Ikeda, M; Ishiko, T; Kubota, H; Kurahashi, Y; Naitoh, M; Suzuki, S; Yamaguchi, H; Yamawaki, S; Yoshikawa, K, 2013) |
| "Keloids and hypertrophic scars are common lesions, which typically present as a cosmetic concern; however, they also can cause significant pruritus and pain." | 1.39 | Combination treatment of CO2 fractional laser, pulsed dye laser, and triamcinolone acetonide injection for refractory keloid scars on the upper back. ( Collawn, SS; Martin, MS, 2013) |
| "Treatment of keloids is a therapeutic challenge." | 1.39 | Retrospective analysis of earlobe keloids treated with the carbon dioxide laser ablation or cold steel debulking surgery. ( Ang, CC; Kwok, C; Tay, YK, 2013) |
| "Keloid is characterized by fibroblastic cell proliferation and abundant collagen synthesis." | 1.39 | Identification and characterization of Wnt signaling pathway in keloid pathogenesis. ( Egawa, S; Ghazizadeh, M; Hyakusoku, H; Igota, S; Murakami, M; Shimizu, H; Tosa, M, 2013) |
| "Keloids are characterized by the vigorously continuous production of extracellular matrix protein and aberrant cytokine activity in the dermis." | 1.39 | Thalidomide inhibits fibronectin production in TGF-β1-treated normal and keloid fibroblasts via inhibition of the p38/Smad3 pathway. ( Chen, YL; Chien, HF; Hung, LY; Lee, CW; Liang, CJ; Pu, CM; Tsai, JS; Wang, SH; Yen, FL; Yen, YH, 2013) |
| "Keloid is a clinically intractable fibro-proliferative disease that spreads beyond the original scar or lesion." | 1.39 | Keloid formation on the great toe after chronic paronychia secondary to ingrown nail. ( Burm, JS; Lee, KW; Yang, WY, 2013) |
| "Keloids are considered aberrations of the wound healing process, and various treatment regimens are described depending on the morphology and size of the lesion." | 1.39 | Reverse activated hyrax pressure appliance for treatment of a keloid located at auricula helix. ( Yüzbaşıoğlu, E, 2013) |
| "Polyfibromatosis is a rare fibrosing condition characterized by fibromatosis in different body areas and by keloid formation, and which can be associated with arthropathy and osteolysis." | 1.39 | Arthropathy, osteolysis, keloids, relapsing conjunctival pannus and gingival overgrowth: a variant of polyfibromatosis? ( Cinotti, E; Di Maria, E; Faravelli, F; Ferrero, G; Papadia, M; Paparo, F; Rongioletti, F; Traverso, C, 2013) |
| "Keloids are the result of an overgrowth of dense fibrous tissue that usually develops after healing of a skin injury." | 1.39 | Keloids: an update on medical and surgical treatments. ( Kundu, RV; Love, PB, 2013) |
| "Keloid is benign fibroproliferative dermal tumors with unknown etiology." | 1.39 | Association study confirmed susceptibility loci with keloid in the Chinese Han population. ( Cheng, H; Ding, Y; Gao, J; Ha, W; Hou, J; Li, P; Liu, J; Liu, Y; Qian, F; Sheng, Y; Sun, L; Tang, H; Wang, J; Wang, W; Wang, Y; Wu, B; Yang, S; Yuan, X; Zhai, Y; Zhang, X; Zhou, F; Zhu, F; Zuo, X, 2013) |
| "Keloids are tumor-like skin scars that grow as a result of the aberrant healing of skin injuries, with no effective treatment." | 1.39 | Comparative study of microRNA profiling in keloid fibroblast and annotation of differential expressed microRNAs. ( Bai, Y; Cao, M; Li, C; Liu, H; Xu, Y; Yao, H; Zuo, X, 2013) |
| "The keloids were grouped according to formation time." | 1.39 | [Expression and significance of DNMT1 in human keloid fibroblast]. ( Yang, E; Zhang, HS; Zou, QP, 2013) |
| "Immediate recurrence was 9." | 1.39 | Earlobe keloids: a pilot study of the efficacy of keloidectomy with core fillet flap and adjuvant intralesional corticosteroids. ( Al Aradi, IK; Alaradi, I; Alawadhi, SA; Alkhawaja, FA, 2013) |
| "Fb of keloid were stimulated with artesunate in various concentration for different time, and the median inhibitory concentration (IC50) was determined with the MTT colorimetric assay, which served as the intervention concentration of artesunate." | 1.39 | [Expressions of the related genes in fibroblasts of human keloid and the effect of artesunate]. ( He, GZ; Ren, YH; Tang, XQ; Xiao, L; Yu, ZH, 2013) |
| "Keloids are tumour-like scars that appear some years after the original wound, and which spread beyond the limits of the scar." | 1.39 | [Bilateral keloids secondary to otoplasty treated by excision and keloids flaps]. ( Escudero Nafs, FJ; Pérez-Espadero, A, 2013) |
| "Only mild and transient post treatment erythema was noted as an adverse effect." | 1.39 | The use of the 300 microsecond 1064 nm Nd:YAG laser in the treatment of keloids. ( Frey, MK; Kubota, T; Lu, R; Perez, M; Rossi, A; Smith, LA, 2013) |
| "Keloids are fibroproliferative disorders characterized by exuberant extracellular matrix deposition and transforming growth factor (TGF)-β/Smad pathway plays a pivotal role in keloid pathogenesis." | 1.39 | Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation. ( Bian, D; Dai, Y; Dou, Y; Gong, Z; Tan, Q; Wu, X; Xia, Y; Yang, Y; Zhang, J, 2013) |
| "Morbidity of the keloid is high, given the frequent recurrences and unpredictable." | 1.39 | [Keloid scars on black skin: myth or reality]. ( Allah, KC; Assi Djè Bi Djè, V; Kossoko, H; Richard Kadio, M; Yéo, S, 2013) |
| "Keloid is the result of excessive deposition of collagen in the dermis and subcutaneous tissues." | 1.39 | Keloid formation after circumcision and its treatment. ( Demirdover, C; Oztan, HY; Sahin, B; Vayvada, H, 2013) |
| "There are no set guidelines for the treatment of keloids and the most common treatments are individualized and depended on the distribution, size, thickness, and consistency of lesions." | 1.39 | Clinical and histologic effects from CO2 laser treatment of keloids. ( Accardo, M; Brongo, S; Cataldo, C; D'Andrea, F; De Francesco, F; Ferraro, GA; Grella, R; Mele, CM; Nicoletti, G, 2013) |
| "Auricular keloids were successfully treated in 93." | 1.39 | Analysis of 15 cases of auricular keloids following conchal cartilage grafts in an asian population. ( Chang, CH; Kim, JK; Park, JH; Park, TH; Rah, DK; Seo, SW, 2013) |
| "Keloids are characterised by the excessive accumulation of extracellular matrix (ECM), especially overabundant collagen formation." | 1.39 | Extract of Aneilema keisak inhibits transforming growth factor-β-dependent signalling by inducing Smad2 downregulation in keloid fibroblasts. ( Bae, GY; Bahk, YY; Cha, HJ; Chin, YW; Kim, JJ; Kim, WS; Lee, JS; Min, HG, 2013) |
| "Evaluation of perioperative treatment of keloid scars with electron beam therapy or iridium 192 low dose rate brachytherapy." | 1.39 | [Adjuvant treatment of keloid scars: electrons or brachytherapy?]. ( Autret, D; Cellier, P; Fernandez, L; Jadaud, E; Krhili, S; Mahé, MA; Mesgouez-Nebout, N; Paumier, A; Poirier, AL; Rio, E; Tuchais, C; Vinchon-Petit, S; Yossi, S, 2013) |
| " This study aimed to compare keloid recurrence rates in patients whose keloids were dressed using conventional methods (plain gauze or a polyvinyl alcohol sponge) with those of a matched cohort of patients whose keloids were dressed using magnets combined with hydrocolloid materials." | 1.39 | Early postoperative magnet application combined with hydrocolloid dressing for the treatment of earlobe keloids. ( Chang, CH; Park, TH, 2013) |
| "Children accounted for 78." | 1.38 | Plastic and reconstructive surgery in Zambia: epidemiology of 16 years of practice. ( Bowman, KG; Corlew, DS; Jovic, G, 2012) |
| "Patients with a history of previous treatment and keloids in the perioral region should be monitored closely for signs of recurrence and managed cautiously during treatment." | 1.38 | Clinical characteristics of facial keloids treated with surgical excision followed by intra- and postoperative intralesional steroid injections. ( Chang, CH; Kim, JK; Park, TH; Seo, SW, 2012) |
| "An established treatment for keloids is surgery and radiotherapy, using a single applied field." | 1.38 | Radiotherapy treatment of keloid scars with a kilovoltage X-ray parallel pair. ( Barber, E; Collis, CH; Eaton, DJ; Ferguson, L; Mark Simpson, G, 2012) |
| "Pirfenidone is a novel anti-fibrotic agent that inhibits the progression of fibrosis occurring in the keloid lesions of the lung and kidney." | 1.38 | Pirfenidone suppresses keloid fibroblast-embedded collagen gel contraction. ( Maeda, T; Matsumura, H; Saito, M; Setoguchi, Y; Tsuboi, R; Yamazaki, M, 2012) |
| "We analyzed the presence of mild cognitive impairment (CI) by using the PHES battery of psychometric tests and measured the levels of ammonia and of the inflammatory cytokines IL-6 and IL-18 in blood of patients with different types of liver or dermatological diseases resulting in different grades of hyperammonemia and/or inflammation." | 1.38 | Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy. ( Cassinello, N; Civera, M; Felipo, V; Garcia-Torres, ML; Jordá, E; Martinez-Valls, J; Molina, I; Montesinos, E; Montoliu, C; Olmo, JA; Ortega, J; Serra, MA; Urios, A; Wassel, A, 2012) |
| "Keloids are benign tumours composed of fibrous tissue produced during excessive tissue repair triggered by minor injury, trauma or surgical incision." | 1.38 | Involvement of upper torso stress amplification, tissue compression and distortion in the pathogenesis of keloids. ( Bux, S; Madaree, A, 2012) |
| "Our analysis indicates that uterine fibroids and keloid scars contain higher amounts of glycosaminoglycans relative to normal myometrium and normal adult skin respectively." | 1.38 | Proteoglycans of uterine fibroids and keloid scars: similarity in their proteoglycan composition. ( Barker, NM; Caplan, AI; Carrino, DA; Hurd, WW; Mesiano, S, 2012) |
| "Keloids are manifestations of abnormal wound repair with unresolved clinical complications." | 1.38 | Altered angiogenic balance in keloids: a key to therapeutic intervention. ( Jayaraman, M; Korrapati, PS; Krishnaswamy, VR; Mogili, NS; Rajaram, R; Venkatraman, A, 2012) |
| "Keloids are a fibroproliferative disease due to abnormal wound healing process after skin injury." | 1.38 | miR-196a downregulation increases the expression of type I and III collagens in keloid fibroblasts. ( Hirano, A; Kashiyama, K; Matsuse, M; Mitsutake, N; Ogi, T; Saenko, VA; Ujifuku, K; Utani, A; Yamashita, S, 2012) |
| "Keloid is a specific skin scar that expands beyond the boundaries of the original injury as it heals." | 1.38 | Madecassoside suppresses migration of fibroblasts from keloids: involvement of p38 kinase and PI3K signaling pathways. ( Bian, D; Dai, Y; Gong, Z; Lu, Q; Song, J; Wei, Z; Xia, Y; Xu, H; Xu, Z, 2012) |
| "Recurrence was defined as return of a raised scar consistent with a keloid scar." | 1.38 | Treatment outcomes for keloid scar management in the pediatric burn population. ( Bailey, JK; Patel, PA; Yakuboff, KP, 2012) |
| "It is necessary to establish the recurrence cut-off scores for each of the scales according to the treatment used." | 1.38 | Evaluating keloid recurrence after surgical excision with prospective longitudinal scar assessment scales. ( Ferreira, LM; Furtado, F; Hochman, B, 2012) |
| "The chance of recurrence increased by 34% at each increase of 1000 arbitrary units in maximum GSR during stress." | 1.38 | Psychological stress as a risk factor for postoperative keloid recurrence. ( Farber, PL; Ferreira, LM; Furtado, F; Hayashi, LF; Hochman, B; Muller, MC, 2012) |
| "Clinically, keloids are defined as scars that invade adjacent healthy tissue and are caused by tissue injury; however, the clear distinction relating keloids to wound healing or to cancer remains elusive." | 1.38 | Protein profiling of keloidal scar tissue. ( Day, PJ; Javad, F, 2012) |
| "Keloids are characterized by extreme fibroblastic overgrowth of unknown pathogenesis after skin injury." | 1.38 | Infrequent p53 gene mutation but UV gradient-like p53 protein positivity in keloids. ( Bambach, I; Cerroni, L; Heitzer, E; Schmidbauer, U; Seidl, H; Wolf, P, 2012) |
| "Keloids are benign dermal tumors characterized by fibroblastic proliferation and excessive accumulation of collagen." | 1.38 | Oxymatrine inhibits collagen synthesis in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway. ( Fan, DL; Guo, S; Han, SY; Wang, YX; Zhao, WJ, 2012) |
| "As tacrolimus (FK506) has been reported to inhibit the effects of TGF-β1 on cultured fibroblasts, we hypothesized that FK506 may be useful in treating keloids." | 1.38 | FK506 inhibits the enhancing effects of transforming growth factor (TGF)-β1 on collagen expression and TGF-β/Smad signalling in keloid fibroblasts: implication for new therapeutic approach. ( Fang, AH; Lan, CC; Wu, CS; Wu, PH, 2012) |
| "Here, we present a distinct dermatofibroma variant henceforth known as collapsing angiokeloidal dermatofibroma identified in 2 patients with slowly growing nodules of the buttock and the arm." | 1.38 | Collapsing angiokeloidal dermatofibroma. ( Brown, JA; Cheung, WL; Hiatt, KM; Schnebelen, AM; Smoller, BR, 2012) |
| "The percentage of after-treatment keloids and hypertrophic scars observed was very low (~1%) especially upon the usage of lower parameters." | 1.38 | Highlights of thirty-year experience of CO2 laser use at the Florence (Italy) department of dermatology. ( Arunachalam, M; Bassi, A; Bonan, P; Bruscino, N; Campolmi, P; Cannarozzo, G; Lotti, T; Moretti, S; Troiano, M, 2012) |
| "Keloids are thick fibrous scars that are refractory to treatment and unique to humans." | 1.38 | Deep and superficial keloid fibroblasts contribute differentially to tissue phenotype in a novel in vivo model of keloid scar. ( Boyce, ST; Glaser, K; Hahn, JM; McFarland, KL; Supp, DM, 2012) |
| "Oral ulcers are relatively common and these lesions cause strong pain and discomfort." | 1.38 | Characterization of oral ulcer and pathological scar in nude mice model. ( Amiranashvili, I; Gogilashvili, Q; Imnadze, I; Sukhitashvili, N; Tabaghua, G, 2012) |
| "Keloid is a complex condition with environmental and genetic risk-contributing factors." | 1.38 | Association of TGFβ1 and SMAD4 variants in the etiology of keloid scar in the Malay population. ( Emami, A; Halim, AS; Kannan, TP; Khoo, TL; Salahshourifar, I; Yussof, SJ, 2012) |
| "Keloids are the result of excessive scar tissue formation." | 1.38 | Botulinum toxin A for the treatment of keloids. ( Bureik, D; Dombrowski, Y; Gauglitz, GG; Pavicic, T; Ruzicka, T; Schauber, J, 2012) |
| "Keloids are benign, fibroproliferative growths that occur as a result of dermal injury in ~15% of the population." | 1.38 | Current concepts in the etiology and treatment of keloids. ( Brissett, AE; Naylor, MC, 2012) |
| "There was no recurrence in a series of average 3." | 1.38 | Are auricular keloids and persistent hypertrophic scars resectable? The role of intrascar excision. ( Yang, JY; Yang, SY, 2012) |
| "To investigate the efficacy of CO2 laser combined with 32P-patch contact brachyradiotherapy for the treatment of keloids." | 1.38 | [Efficacy of CO2 laser combined with 32P-patch contact brachyradiotherapy for the treatment of keloids]. ( Yan, DJ; Yang, HP, 2012) |
| "In pathological scar, mRNA and protein of eIF4E and Mcl-1 showed a strong positive correlation." | 1.38 | [Expression and significance of mRNA and protein of eIF4E, p-eIF4E and MCl-1 in pathological scar]. ( Wang, ZY; Wu, WY; Zhang, LT; Zheng, ZF; Zhu, SZ, 2012) |
| "Keloids are a common form of pathologic wound healing characterized by excessive production of extracellular matrix." | 1.37 | Unfolded protein response regulation in keloid cells. ( Butler, PD; Koong, AC; Longaker, MT; Ly, DP; Wang, Z; Yang, GP, 2011) |
| "TSG-6 is expressed in unscarred skin, where its close association with HA and IαI could give rise to TSG-6-mediated HC•HA formation within this tissue." | 1.37 | Characterization of hyaluronan and TSG-6 in skin scarring: differential distribution in keloid scars, normal scars and unscarred skin. ( Bayat, A; Day, AJ; McGrouther, DA; Milner, CM; Tan, KT, 2011) |
| "Auricular keloids are very frequent and often have a peculiar response to therapy." | 1.37 | Postoperative radiotherapy of auricular keloids: a 26-year experience. ( Caccialanza, M; Piccinno, R; Recalcati, S, 2011) |
| "The spontaneous keloids are lesions rarely described in caucasoid subjects." | 1.37 | [Spontaneous keloids: about a rare case]. ( Boloorchi, A; Gasnier, P; Hu, W; Kerfant, N; Uguen, A, 2011) |
| "Keloids are fibroproliferative disorders characterized by increased deposition of extracellular matrix components." | 1.37 | The role of stem cell factor and c-KIT in keloid pathogenesis: do tyrosine kinase inhibitors have a potential therapeutic role? ( Cao, X; Chan, SY; Do, DV; Khoo, YT; Lim, CP; Lim, IJ; Masilamani, J; Mukhopadhyay, A; Ong, CT; Phan, TT; Vincent, AS; Wong, PK, 2011) |
| "Keloid is a common complication of the wound healing process." | 1.37 | Cell talk: a phenomenon observed in the keloid scar by immunohistochemical study. ( Ayuob, NN; Hajrah, NH; Shaker, SA, 2011) |
| "We sought to evaluate postsurgical adhesions in women of different races with or without keloids." | 1.37 | Prospective study of intraabdominal adhesions among women of different races with or without keloids. ( Akbar, G; Al-Sannan, B; Miner, L; Tulandi, T; Ziegler, C, 2011) |
| "Keloids are fibroproliferative dermal lesions characterized by the proliferation of fibroblasts and the formation of excess scar tissue, for which no effective treatment exists." | 1.37 | Adenovirus-mediated human interleukin 24 (MDA-7/IL-24) selectively suppresses proliferation and induces apoptosis in keloid fibroblasts. ( Huang, Q; Huang, RL; Liang, J; Peng, Z; Wu, ZX; Zhang, PH, 2011) |
| "Keloids are found only in humans and the underlying biochemical mechanisms of their pathogenesis remain unknown." | 1.37 | The role of R-spondin2 in keratinocyte proliferation and epidermal thickening in keloid scarring. ( Chua, AW; Fu, Z; Gan, SU; Han, HC; Ma, D; Phan, TT; Sabapathy, K; Song, C, 2011) |
| "Keloids and hypertrophic scars are significant symptomatic clinical problems characterized by the excessive and abnormal deposition of collagen-based extracellular matrix (ECM) components." | 1.37 | Smad interacting protein 1 as a regulator of skin fibrosis in pathological scars. ( Bai, XZ; Cai, WX; Hu, DH; Liu, JQ; Shi, JH; Tang, CW; Wang, HT; Zhang, YG; Zhang, ZF; Zhao, ZT; Zhu, HY, 2011) |
| "Tacrolimus is an immunomodulator that could be useful in treating keloid." | 1.37 | Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis. ( Blondel, WC; Chassagne, JF; Gisquet, H; Guillemin, F; Latarche, C; Leroux, A; Liu, H; Merlin, JL; Peiffert, D, 2011) |
| "Keloids are common abnormal raised fibroproliferative lesions that can occur following even minor cutaneous trauma." | 1.37 | Association of HLA haplotype with keloids in Chinese Hans. ( Cai, LQ; Li, Y; Lu, WS; Sun, LD; Wang, ZX; Yang, S; Zhang, XJ; Zheng, HF; Zhu, F; Zuo, XB, 2011) |
| "We have treated keloids using a combination of surgical excision and postoperative irradiation." | 1.37 | Keloids can be forced into remission with surgical excision and radiation, followed by adjuvant therapy. ( Ishiko, T; Muneuchi, G; Naitoh, M; Suzuki, S; Yamawaki, S, 2011) |
| "The authors treated 58 chest keloid patients with surgical excision followed by intraoperative and postoperative intralesional steroid injection." | 1.37 | Management of chest keloids. ( Chang, CH; Kim, JK; Park, TH; Seo, SW, 2011) |
| "Keloids are protrusive claw-like scars that have a propensity to recur even after surgery, and its molecular etiology remains elusive." | 1.37 | Insights gained from the reverse engineering of gene networks in keloid fibroblasts. ( Ooi, BN; Phan, TT, 2011) |
| "Keloids are often refractive to treatment, and recurrences occur quite frequently." | 1.37 | Radiofrequency tissue volume reduction for treatment of auricle keloids. ( Fruth, K; Gouveris, H; Kuelkens, C; Mann, WJ, 2011) |
| " Ultraviolet B irradiation with a minimal dosage of 150 mJ/cm(2) is a promising method of keloid prevention and treatment." | 1.37 | Cellular viability, collagen deposition, and transforming growth factor β1 production among ultraviolet B-irradiated keloid fibroblasts. ( Budiyanto, A; Radiono, S; Soebono, H; Wirohadidjojo, YW, 2011) |
| "Hypertrophic scars were created dorsally in rats by incisions." | 1.37 | Transcriptional inhibition of hypertrophic scars by a gene silencer, pyrrole-imidazole polyamide, targeting the TGF-β1 promoter. ( Fukuda, N; Matsuda, H; Matsumoto, Y; Nagase, H; Terui, T; Washio, H; Watanabe, T, 2011) |
| "Keloids are benign skin tumours occurring during wound healing in genetically predisposed patients." | 1.37 | Collagen triple helix repeat containing-1 inhibits transforming growth factor-b1-induced collagen type I expression in keloid. ( Cao, J; Chen, H; Li, J; Li, M; Tu, Y; Wang, L; Wu, Z; Xiao, X; Yang, Y; Yu, Y, 2011) |
| "The authors treated 1436 ear keloids in 883 patients with surgical excision followed by pressure therapy using magnets at Kangbuk Samsung Hospital over the 7." | 1.37 | Outcomes of surgical excision with pressure therapy using magnets and identification of risk factors for recurrent keloids. ( Chang, CH; Kim, JK; Park, TH; Seo, SW, 2011) |
| "It is important that scar mechanobiology be understood from the perspective of the extracellular matrix and extracellular fluid, in order to analyze mechanotransduction pathways and develop new strategies for scar prevention and treatment." | 1.37 | Mechanobiology of scarring. ( Ogawa, R, 2011) |
| "Keloids are pathologic proliferations of the dermal layer of the skin resulting from excessive collagen production and deposition." | 1.37 | Effects of hepatocyte growth factor on collagen synthesis and matrix metalloproteinase production in keloids. ( Lee, WJ; Park, SE; Rah, DK, 2011) |
| "Scars are usually classified into atrophic scars, hypertrophic scars, or keloids." | 1.37 | Scars. ( Choudhary, S; Elsaie, ML; McLeod, M; Nouri, K, 2011) |
| "In the event that a keloid is presented in isolation, chronic osteomyelitis should be considered as a differential diagnosis, and a high index of suspicion is required in order to establish the diagnosis." | 1.37 | Chronic osteomyelitis in the lower extremity predisposing to the unusual formation of keloids. ( Olabanji, JK; Oladele, AO; Orimolade, EA; Yusuf, MB, 2011) |
| "Keloid is a common skin condition, especially in people of Asian and African decent." | 1.37 | Is photodynamic therapy a solution for keloid? ( Nie, Z, 2011) |
| "Keloid is regarded as a fibroproliferative disorder with excessive accumulation of extracellular matrix." | 1.37 | Effect of heat shock protein 47 on collagen synthesis of keloid in vivo. ( Cen, Y; Chen, JJ; Duan, WQ; Jin, PS; Liu, Y; Wang, HS; Xu, XW; Zhao, S, 2011) |
| "Keloids are defined as excessive scar tissue formation extending beyond the area of the original skin injury and occurring in predisposed individuals." | 1.37 | Giant keloid of left buttock treated with post-excisional radiotherapy. ( Guglielmi, G; Parisi, S; Scaramuzzi, G; Simeone, A; Troiano, M, 2011) |
| "Atypical fibroxanthoma (AFX) with prominent fibrosis, sclerosis and hyalinization, and near-total tumor regression is rare." | 1.36 | The histopathologic spectrum of regression in atypical fibroxanthoma. ( Calonje, JE; Robson, A; Stefanato, CM, 2010) |
| "Keloids are recognized as benign tumours characterized by fibroblastic proliferation and accumulation of extracellular matrix, especially collagen deposition." | 1.36 | Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts. ( He, S; Huang, W; Liu, X; Roberts, MS; Xu, S; Yang, S; Yang, Y; Zhang, X, 2010) |
| "Keloids are associated with small-fiber neuropathy and typically present with itching, pain, and allodynia." | 1.36 | Treatment of a painful keloid with botulinum toxin type A. ( Dave, S; Lippincott, B; Uyesugi, B, 2010) |
| "Keloids are benign fibroproliferative dermal tumors of unknown etiology." | 1.36 | Association of HLA class I alleles with keloids in Chinese Han individuals. ( Cai, LQ; He, SM; Li, Y; Lu, WS; Quan, C; Wang, JF; Wang, ZX; Xiao, FL; Yang, S; Zhang, XJ, 2010) |
| "The authors present their experience of treating earlobe keloids using the "sandwich" technique protocol; extralesional excision and external-beam radiotherapy are given a day before and a day after the operation." | 1.36 | Treatment of earlobe keloids by extralesional excision combined with preoperative and postoperative "sandwich" radiotherapy. ( Amir, A; Barnea, Y; Ben-Yosef, R; Gur, E; Leshem, D; Miller, E; Shafir, R; Stahl, S; Weiss, J; Zaretski, A, 2010) |
| "Keloids are fibrous overgrowth induced by cutaneous injury." | 1.36 | Enhanced MCP-1 release by keloid CD14+ cells augments fibroblast proliferation: role of MCP-1 and Akt pathway in keloids. ( Arbiser, JL; Chai, CY; Chen, GS; Govindarajan, B; Hong, CH; Lee, CH; Liao, WT; Lin, YF; Shan, WJ; Yu, HS, 2010) |
| "They all end up with a scar unless there is an unusual situation where we are operating on an early gestation fetus." | 1.36 | Regenerative medicine: a surgeon's perspective. ( Longaker, MT, 2010) |
| "Large and multiple keloids are difficult to treat radically and are currently only treatable by multimodal therapies that aim to relieve symptoms." | 1.36 | The most current algorithms for the treatment and prevention of hypertrophic scars and keloids. ( Ogawa, R, 2010) |
| "Keloids are pathological scars and, despite numerous available treatment modalities, continue to plague physicians and patients." | 1.36 | Comparative proteomic analysis between normal skin and keloid scar. ( Do, DV; Khoo, YT; Lim, IJ; Masilamani, J; Mukhopadhyay, A; Ong, CT; Phan, TT, 2010) |
| "Keloids are a response to wound healing that occurs due to hyperproliferation of dermal collagen in response to skin injury (Olabanji et al, Surg Pract." | 1.36 | The role of full-thickness skin grafting and steroid injection in the treatment of auricular keloids. ( Brown, NA; Ortega, FR, 2010) |
| "Keloids are common abnormal raised fibroproliferative lesions that can occur following even minor cutaneous trauma." | 1.36 | Association of HLA-DRB1 alleles with keloids in Chinese Han individuals. ( Cai, LQ; Li, Y; Lu, WS; Sun, LD; Wang, JF; Wang, ZX; Yang, S; Zhang, WY; Zhang, XJ; Zhu, F; Zuo, XB, 2010) |
| "Keloids are benign dermal tumors that form during wound healing in genetically susceptible individuals." | 1.36 | Epigenetically altered wound healing in keloid fibroblasts. ( Broquist, AH; Gayden, AE; Nanney, LB; Opalenik, SR; Raju, L; Russell, JD; Russell, SB; Trupin, KM; Williams, SM, 2010) |
| "A deep core biopsy of the treated keloid performed three months following the last electrochemotherapy session showed no evidence of chronic lymphocytic leukaemia." | 1.36 | Electrochemotherapy treatment of a recalcitrant earlobe keloid scar with chronic lymphocytic leukaemia infiltration. ( Allison, KP; Muir, T; Sainsbury, DC, 2010) |
| "A case is presented with fourth recurrence of keloids after surgical treatment of lop ears with final satisfactory outcome after combined therapy that included surgical excision, skin flap transposition and radiotherapy." | 1.36 | [Surgical and radiotherapy in treatment of postauricular keloids--case report]. ( Ahmetasević, SG; Barisić, J; Grah, J; Gverić, T; Huljev, D; Ivkosić, A; Trajbar, D; Zdilar, B, 2010) |
| "Hypertrophic and keloid scars result from alterations in the wound healing process." | 1.36 | Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: a case series. ( Barolet, D; Boucher, A, 2010) |
| "Keloid is a dermal fibroproliferative growth that results from dysfunction of the wound healing processes." | 1.36 | A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population. ( Chung, S; Hosono, N; Kamatani, N; Kawaguchi, T; Kubo, M; Nakamura, Y; Nakashima, M; Takahashi, A; Tsunoda, T; Zembutsu, H, 2010) |
| "Curcuminoids have been found to inhibit fibrosis." | 1.36 | Suppression of TGF-β1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid. ( Chang, CC; Chen, MJ; Hsu, YC; Ko, SY; Yu, YM, 2010) |
| "Keloids and hypertrophic scars are both abnormal wound responses in predisposed individuals but they differ in that keloids extend beyond the original wound and almost never regress, while hypertrophic scars remain within the original wound and tend to regress." | 1.36 | Treatment of hypertrophic scars and keloids with a fractional CO2 laser: a personal experience. ( Catalani, A; Lomeo, G; Nolfo, C; Perrotta, RE; Pompili, G; Scrimali, L; Siragò, P; Tamburino, S, 2010) |
| "A silicone gel sheet is effective for treating keloid scars following median sternotomy." | 1.36 | Experience of silicone gel sheets for patients with keloid scars after median sternotomy. ( Akahoshi, T; Miyasaka, Y; Sakuraba, M; Suzuki, K; Takahashi, N, 2010) |
| "The progression of keloids is characterized by increased deposition of extracellular matrix proteins, invasion into the surrounding healthy skin and inflammation." | 1.36 | Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option. ( Bayat, A; Dienus, K; Gilmore, BF; Seifert, O, 2010) |
| "Keloids and hypertrophic scars are extremely disturbing to patients, both physically and psychologically." | 1.35 | Treatment of hypertrophic scars and keloids using intense pulsed light (IPL). ( Agaoglu, G; Erol, OO; Gurlek, A; Oz, H; Topcuoglu, E, 2008) |
| "Excessive scar formation in keloids points to altered tissue modeling and repair mechanisms." | 1.35 | Gene expression profiling reveals alteration of caspase 6 and 14 transcripts in normal skin of keloid-prone patients. ( Berman, B; Elgart, G; Gugic, D; Jacob, SE; Nassiri, M; Ramos, S; Romanelli, P; Viciana, A; Vincek, V; Woolery-Lloyd, H, 2009) |
| "Keloids are tumor-like skin scars that grow as a result of the aberrant healing of skin injuries, with no effective treatment." | 1.35 | Adenoviral overexpression and small interfering RNA suppression demonstrate that plasminogen activator inhibitor-1 produces elevated collagen accumulation in normal and keloid fibroblasts. ( Benya, PD; Chang, R; Ho, W; Hwu, P; Tuan, TL; Wysocki, A; Yiu, P, 2008) |
| "Keloids are considered to be benign hyperproliferative growths of dense fibrous tissue and overabundant deposition of disorganized, thick, hyalinized collagen that result from an abnormal tissue response to cutaneous injury." | 1.35 | Surgical treatment of earlobe keloid with CO2 laser radiation: case report and clinical standpoints. ( De Oliveira Moura Cardoso, G; Morosolli, AR; Murilo-Santos, L; Niccoli-Filho, W, 2008) |
| "The pathogenesis of keloid is poorly understood." | 1.35 | Human mesenchymal stem cells may be involved in keloid pathogenesis. ( Akino, K; Akita, S; Hayashi, T; Hirano, A; Mineda, T; Yakabe, A, 2008) |
| "Acute pain was evaluated in all 21 patients." | 1.35 | Reduction of pain in the treatment of vascular lesions with a pulsed dye laser and pneumatic skin flattening. ( Lanigan, S, 2009) |
| "The term cutaneous pseudolymphoma has been coined to describe the accumulation of either T or B cell lymphocytes in the skin that is caused by a nonmalignant stimulus and encompasses several different terms depending on etiology." | 1.35 | Plasma-cell-predominant B-cell pseudolymphoma. ( Nervi, SJ; Schwartz, RA, 2008) |
| "Keloids are benign skin tumors and are the effect of a dysregulated wound-healing process in genetically predisposed patients." | 1.35 | Differential apoptosis markers in human keloids and hypertrophic scars fibroblasts. ( De Felice, B; Garbi, C; Santillo, A; Santoriello, M; Wilson, RR, 2009) |
| "Keloids are raised reddish nodules that develop at the site of an injury." | 1.35 | A custom-made silicon mold for pressure therapy to ear keloids. ( Alyanak, A; Guven, E; Yazar, M; Yigit, B, 2009) |
| "Keloid is characterized by excessive deposition of collagen, resulting from aberrant extracellular matrix (ECM) production and degradation." | 1.35 | Promoted activation of matrix metalloproteinase (MMP)-2 in keloid fibroblasts and increased expression of MMP-2 in collagen bundle regions: implications for mechanisms of keloid progression. ( Akasaka, Y; Imaizumi, R; Inomata, N; Ishikawa, Y; Ito, K; Maruyama, Y; Okada, E, 2009) |
| "We observed 23." | 1.35 | Keloids treated with postoperative Iridium 192* brachytherapy: a retrospective study. ( Arnault, JP; Barbaud, A; Chassagne, JF; Latarche, C; Peiffert, D; Schmutz, JL, 2009) |
| "Keloids and other scars are different manifestations of the normal wound healing process." | 1.35 | Do postsurgical interventions optimize ultimate scar cosmesis. ( Amini, S; Berman, B; Konda, S; Viera, MH, 2009) |
| "Familial keloids have been reported, having either autosomal dominant or autosomal recessive inheritance." | 1.35 | Description of familial keloids in five pedigrees: evidence for autosomal dominant inheritance and phenotypic heterogeneity. ( Clark, JA; Howard, L; Kleta, R; Kopp, JB; Stanescu, H; Turner, ML, 2009) |
| "Keloids are benign skin tumors that are the effect of a dysregulated wound-healing process in genetically predisposed patients." | 1.35 | Telomere shortening may be associated with human keloids. ( De Felice, B; Nacca, M; Wilson, RR, 2009) |
| "Keloid is a fibrotic disease characterized by abnormal accumulation of extracellular matrix in the dermis." | 1.35 | Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid. ( Ikeda, M; Ishiko, T; Kubota, H; Kurokawa, M; Nagata, K; Naitoh, M; Nakamura, T; Suzuki, S; Utani, A; Yamawaki, S; Yoshikawa, K, 2009) |
| "Keloids have a predilection for the aural region because of the special shape of the pinna." | 1.35 | Clinical improvement in the therapy of aural keloids. ( Cen, Y; Liu, XX; Xu, XW; Yu, R; Zhang, YG, 2009) |
| "Keloids are benign tumors of the dermis that form during a protracted wound healing process." | 1.35 | Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways. ( Boone, BE; Opalenik, SR; Russell, SB; Smith, JC; Williams, SM, 2008) |
| "Keloids are pathologic scars afflicting a large segment of our population and for which there is no definitive therapy." | 1.35 | Use of organotypic coculture to study keloid biology. ( Butler, PD; Longaker, MT; Ly, DP; Yang, GP, 2008) |
| "Keloids are a frequent finding after physical trauma." | 1.35 | Management of external ear keloids using form-pressure therapy. ( Chrisostomidis, C; Chrisostomidis, G; Dimitroulis, D; Frangoulis, M; Konofaos, P; Papadopoulos, O; Vasilopoulou, A, 2008) |
| "We present a case of acquired syndactyly secondary to keloid formation in a previously normal web space following release of syndactyly in the adjacent web space." | 1.35 | Keloid formation resulting in acquired syndactyly of an initially normal web space following syndactyly release of an adjacent web space. ( Lawson, RD; Tonkin, MA; Willis, KR, 2008) |
| "Transforming growth factor beta (TGF-beta) has been implicated in scar formation through the activation of fibroblasts and the acceleration of collagen deposition." | 1.35 | A novel truncated TGF-beta receptor II downregulates collagen synthesis and TGF-beta I secretion of keloid fibroblasts. ( Chu, Y; Guo, F; Guo, Y; Li, X; Li, Y; Zhou, T, 2008) |
| "The etiology and formation pattern of heterotopic ossifications (HO) are still unknown." | 1.35 | Two peculiar conditions following a coma: a clinical case of heterotopic ossification concomitant with keloid formation. ( Bertoni, L; Bonucci, P; Cavani, F; Celli, A; Ferretti, M; Palumbo, C; Rovesta, C; Sena, P, 2008) |
| "Keloids are benign skin tumors characterized by collagen accumulation and hyperproliferation of fibroblasts." | 1.35 | Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway. ( Jun, EK; Kim, B; Kim, H; Moon, JH; Noh, JY; Oh, C; Oh, S; Park, G; Song, HJ; Yoon, BS; You, S, 2008) |
| "Fibrosis is a major cause of human death and disability." | 1.34 | Does transformation of microvascular endothelial cells into myofibroblasts play a key role in the etiology and pathology of fibrotic disease? ( Karasek, MA, 2007) |
| "Keloids are cosmetically devastating lesions with considerable morbidity." | 1.34 | IL-6 signaling pathway in keloids: a target for pharmacologic intervention? ( Uitto, J, 2007) |
| "Several options are described to treat keloid scars, none of them being 100% successful." | 1.34 | Is the treatment of keloid scars still a challenge in 2006? ( Boeckx, WD; De Lorenzi, F; Lutgens, LC; Nieman, FH; Rhemrev, R; Tielemans, HJ; van der Hulst, RR, 2007) |
| "Keloids are defined as dermal fibrotic lesions which are considered an aberration of the wound healing process." | 1.34 | Combination of surgical excision and custom designed silicon pressure splint therapy for keloids on the helical rim. ( Altmeyer, P; Bechara, FG; Boorboor, P; Hoffmann, K; Mann, B; Sand, D; Sand, M, 2007) |
| "Keloid is a dermal fibroproliferative disorder characterized by excessive deposition of extracellular matrix (ECM) components such as collagen, glycoproteins and fibronectin." | 1.34 | mTOR as a potential therapeutic target for treatment of keloids and excessive scars. ( Aalami, O; Do, DV; Khoo, YT; Lim, IJ; Mukhopadhyay, A; Ong, CT; Phan, TT, 2007) |
| "Keloid was identified in 13 boys and 10 girls, accounting for 0." | 1.34 | Prevalence of childhood acne, ephelides, warts, atopic dermatitis, psoriasis, alopecia areata and keloid in Kaohsiung County, Taiwan: a community-based clinical survey. ( Chen, W; Cheng, YW; Lai, CS; Yang, YC, 2007) |
| "Keloid is characterized by excessive collagen accumulation, but the mechanism of keloid formation remains unknown, and none of the treatment modalities are consistently effective." | 1.34 | Effect of heat shock protein 47 on collagen accumulation in keloid fibroblast cells. ( Cen, Y; Chen, JJ; Liu, XX; Wu, DM; Yu, R; Zhao, S, 2007) |
| "Keloids and hypertrophic scars have several common features." | 1.34 | Factor XIIIa-positive dermal dendritic cells in keloids and hypertrophic and mature scars. ( Igawa, HH; Ito, O; Onodera, M; Sakamoto, H; Suzuki, S; Ueno, M, 2007) |
| "Trichilemmal carcinoma is a rare cutaneous adnexal malignant tumor deriving from the outer root sheath of hair follicles." | 1.34 | Trichilemmal carcinoma of the skin mimicking a keloid in a heart transplant recipient. ( Claudy, A; Euvrard, S; Kanitakis, J; Sebbag, L, 2007) |
| "Leiomyoma have often been compared to keloids because of their fibrotic characteristic and higher rate of occurrence among African Americans as compared to other ethnic groups." | 1.34 | Genomic and proteomic profiling II: comparative assessment of gene expression profiles in leiomyomas, keloids, and surgically-induced scars. ( Chegini, N; Liu, L; Luo, X; Pan, Q, 2007) |
| "Transforming growth factor beta (TGF-beta) plays a central role in the pathogenesis of fibrosis by inducing and sustaining activation of keloid fibroblasts." | 1.34 | Inhibition of Smad3 expression decreases collagen synthesis in keloid disease fibroblasts. ( Gao, Z; Hou, T; Jiang, H; Jin, Y; Lin, Z; Shi, Y; Sun, Y; Wang, Q; Wang, Z; Wu, H; Yuan, X; Zhu, X, 2007) |
| "The primary protocol presented for the treatment of ear keloids produces durable results, with an acceptably low recurrence rate." | 1.34 | A primary protocol for the management of ear keloids: results of excision combined with intraoperative and postoperative steroid injections. ( Freeman, K; Patel, MK; Rosen, DJ; Weiss, PR, 2007) |
| "Patients with neurofibromatosis/solitary neurofibroma, who were operated on from 1990 to 2000, were evaluated by reviewing their medical charts and photographs retrospectively." | 1.34 | Multicenter study of wound healing in neurofibromatosis and neurofibroma. ( Agbenorku, P; Billings, B; Har-Shai, Y; Jackson, IT; Kokuba, E; Kurihara, K; Miyawaki, T; Moreira-Gonzalez, A; Tsukuno, M, 2007) |
| "Keloid is a hypertrophic scar that may arise within 6 months after injury in susceptible individuals." | 1.34 | Unilateral keloid formation after bilateral breast surgery and unilateral radiation. ( Bölke, E; Budach, W; Gripp, S; Matuschek, C; Orth, K; Peiper, M; Schwarz, A, 2007) |
| "Seven keloids were treated postoperatively with three fractions of 6 Gy." | 1.34 | Postoperative high-dose-rate brachytherapy in the prevention of keloids. ( Kal, HB; Veen, RE, 2007) |
| "Keloids are proliferative dermal growths representing a pathologic wound healing response." | 1.34 | Increased CCN2 transcription in keloid fibroblasts requires cooperativity between AP-1 and SMAD binding sites. ( Kong, W; Lim, IJ; Longaker, MT; Phan, TT; Wang, Z; Xia, W; Yang, GP, 2007) |
| "Mitomycin C (MC) is an anti-neoplastic agent with an anti-proliferative effect on fibroblasts." | 1.33 | Use of mitomycin C for treatment of keloid: a preliminary report. ( Kronenberg, J; Orenstein, A; Talmi, YP; Wolf, M, 2005) |
| "Keloid is a dermal fibroproliferative lesion of unknown etiology that commonly recurs after surgical excision." | 1.33 | Global gene expression analysis of keloid fibroblasts in response to electron beam irradiation reveals the involvement of interleukin-6 pathway. ( Ghazizadeh, M; Hirai, T; Hyakusoku, H; Kawanami, O; Shimizu, H; Tosa, M, 2005) |
| "Given the difficulty and cost of treating keloids, prevention remains the best approach." | 1.33 | Relationship between age of ear piercing and keloid formation. ( Davis, LS; Lane, JE; Waller, JL, 2005) |
| "Most of the foreign bodies were very fine or sand-like." | 1.33 | Treatment of scattered glass foreign bodies in both the superficial and deep neck: a case report. ( Fujieda, S; Imoto, Y; Ito, Y; Kouraba, S; Narita, N; Ogi, K; Sakashita, M; Tsuzuki, H; Yamada, T; Yasuta, M, 2005) |
| "Keloids are common lesions arising from sites of a previous trauma, and are distinguishable from scars by the presence of continuous growth over the borders of the original injury." | 1.33 | Comparative study of keloid formation in humans and laboratory animals. ( Khorshid, FA, 2005) |
| "Keloids are benign skin tumours occurring during wound healing in genetically predisposed patients." | 1.33 | Studies of transforming growth factors beta 1-3 and their receptors I and II in fibroblast of keloids and hypertrophic scars. ( Bayat, A; Bock, O; Ferguson, MW; Mrowietz, U; Yu, H; Zitron, S, 2005) |
| "The vessel count of hypertrophic scar, keloid was significantly abundant compared with surgical scar or normal skin (P < 0." | 1.33 | [Relationship between angiogenesis and expression of HO-1 of scar]. ( He, QY; Li, P; Luo, CQ; Peng, H; Zhou, JD; Zhu, J, 2005) |
| "A keloid is a specific skin lesion that expands beyond the boundaries of the original injury as it heals." | 1.33 | Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration. ( Fujiwara, M; Muragaki, Y; Ooshima, A, 2005) |
| "Keloids are disfiguring, proliferative scars that are a pathologic response to cutaneous injury." | 1.33 | Photodynamic therapy on keloid fibroblasts in tissue-engineered keratinocyte-fibroblast co-culture. ( Chiu, LL; Karamzadeh, A; Sun, CH; Torkian, B; Tromberg, B; Wong, BJ; Yeh, AT, 2005) |
| "Keloids are tumor-like lesions that result from excessive scar formation during healing of wounds." | 1.33 | Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity. ( Fujiwara, M; Muragaki, Y; Ooshima, A, 2005) |
| "Keloids are a dermal fibrotic disease whose etiology remains totally unknown and for which there is no successful treatment." | 1.33 | Gene expression in human keloids is altered from dermal to chondrocytic and osteogenic lineage. ( Ikeda, M; Kubota, H; Nagata, K; Naitoh, M; Shirane, H; Suzuki, S; Tanaka, T, 2005) |
| "Keloids are a hyperproliferative response of connective tissue in response to trauma." | 1.33 | Defective induction of senescence during wound healing is a possible mechanism of keloid formation. ( Blazić, TM; Brajac, I, 2006) |
| "Keloids are benign cutaneous lesions that result from excessive collagen synthesis and deposition." | 1.33 | Cryosurgery in the treatment of earlobe keloids: report of seven cases. ( Fikrle, T; Pizinger, K, 2005) |
| "Keloids are proliferative growths of dermal collagen, usually resulting from excessive tissue response during wound healing." | 1.33 | Up-regulation of metallothionein isoforms in keloid keratinocytes. ( Bay, BH; Lim, D; Phan, TT; Yip, GW, 2006) |
| "Keloids are abnormal fibrous growths of the dermis that develop only in response to wounding and represent a form of benign skin tumor." | 1.33 | P38 MAP kinase mediates transforming growth factor-beta2 transcription in human keloid fibroblasts. ( Longaker, MT; Xia, W; Yang, GP, 2006) |
| "In addition, primary keloid and normal scar skin fibroblast cultures were set up to investigate the effects of NO in inducing collagen type I expression." | 1.33 | Nitric oxide produced by iNOS is associated with collagen synthesis in keloid scar formation. ( Chien, YW; Hsiao, M; Hsu, YC; Lee, WR; Wang, LF, 2006) |
| "Keloids are benign tumors that occur only in response to injury, for which there is no effective treatment." | 1.33 | Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation. ( Lim, IJ; Longaker, MT; Phan, TT; Xia, W; Yang, GP, 2006) |
| "Keloids are benign skin tumours occurring during wound healing in genetically predisposed patients." | 1.33 | Decreased expression of inhibitory SMAD6 and SMAD7 in keloid scarring. ( Bayat, A; Bock, O; Ferguson, MW; Mrowietz, U; Yu, H, 2006) |
| "This pilot study suggests that treatment of keloid and hypertrophic scars with intra-lesional injections of collagenase is ineffective." | 1.33 | Intra-lesional injections of collagenase are ineffective in the treatment of keloid and hypertrophic scars. ( Gault, D; Kang, N; Nduka, C; Sanders, R; Sivakumar, B, 2006) |
| "Keloids were localised on the lower lobe of the ear (n=10), on the ear lobe (n=3), on the neck (n=1), on the pubis (n=1), and on the presternal area (n=1)." | 1.33 | [Treatment of keloids with shaving and cryosurgery: preliminary reports]. ( Boullie, MC; Dehesdin, D; Joly, P; Sellier, S, 2006) |
| "Keloids are benign hyperproliferative growths of dermal collagen that usually result from excessive tissue response to skin trauma." | 1.33 | A rare complication after circumcision: keloid of the penis. ( Erdemir, F; Gokce, O; Kadioglu, A; Kilicaslan, I; Parlaktas, BS; Sanli, O; Uluocak, N, 2006) |
| "Mitomycin-C is a chemotherapeutic agent that inhibits DNA synthesis and fibroblast proliferation." | 1.33 | Application of mitomycin-C for head and neck keloids. ( Kim, JY; Stewart, CE, 2006) |
| "Keloids are benign tumors that usually develop as an excessive healing response to injury." | 1.33 | Different therapeutic modalities in a patient with multiple spontaneously developed keloids--a case report. ( Bukvić-Mokos, Z; Lipozencić, J; Marinović, B, 2006) |
| "Plantar keloids are a management problem as a result of the pain and mechanic restriction with ambulation." | 1.32 | Giant right plantar keloid treated with excision and tissue-engineered allograft. ( Elston, DM; Osswald, SS; Vogel, PS, 2003) |
| "Keloids are benign diseases of the skin." | 1.32 | [Radiotherapy of keloids. Patterns of care study -- results]. ( Kutzner, J; Schneider, L; Seegenschmiedt, MH, 2003) |
| "Keloids are the result of aberrant wound healing of human skin after dermal injury." | 1.32 | Effect of mitomycin C on keloid fibroblasts: an in vitro study. ( Alani, H; Simman, R; Williams, F, 2003) |
| "Transforming growth factor beta1 (TGF-beta1) plays a central role in wound healing and fibrosis and has been implicated in the pathogenesis of keloid disease and hypertrophic scar." | 1.32 | Genetic susceptibility to keloid disease and hypertrophic scarring: transforming growth factor beta1 common polymorphisms and plasma levels. ( Bayat, A; Bock, O; Ferguson, MW; Mrowietz, U; Ollier, WE, 2003) |
| "Those keloids were surgically removed, and the patients were treated postoperatively with 15-Gy electron-beam irradiation and followed for more than 18 months." | 1.32 | Postoperative electron-beam irradiation therapy for keloids and hypertrophic scars: retrospective study of 147 cases followed for more than 18 months. ( Hyakusoku, H; Mitsuhashi, K; Miyashita, T; Ogawa, R, 2003) |
| " The bioavailability of IGF-I may be related to the levels of IGFBP-3 produced, which in turn influences KF proliferation, suggesting that modulation of IGF-I, IGF-IR, and IGFBP-3, individually or in combination, may represent novel approaches to the treatment of keloids." | 1.32 | Role of IGF system of mitogens in the induction of fibroblast proliferation by keloid-derived keratinocytes in vitro. ( Bay, BH; Huynh, H; Lee, ST; Lim, IJ; Longaker, MT; Phan, TT; Qi, R, 2003) |
| "A 53-year-old woman with systemic sclerosis developed numerous cutaneous nodules, resembling keloids, on her anterior chest wall." | 1.32 | Keloidal scleroderma. ( Andrew, SM; Brammah, T; Griffiths, CE; Herrick, AL; Ling, TC, 2003) |
| "Participants (n = 80) were treated for 80 keloid scars (59 percent female patients, 76 percent nonwhite), and 44 percent of keloids were located on earlobes." | 1.32 | Treatment of keloids by surgical excision and immediate postoperative single-fraction radiotherapy. ( Cornes, PG; Glees, JP; Moss, AL; Ragoowansi, R, 2003) |
| "Keloids are benign dermal tumors, characterized by invasive growth of fibroblasts and concomitant increased biosynthesis of extracellular matrix components, with unclear etiology." | 1.32 | Insulin-like growth factor-I enhances transforming growth factor-beta-induced extracellular matrix protein production through the P38/activating transcription factor-2 signaling pathway in keloid fibroblasts. ( Akiyama-Uchida, Y; Daian, T; Fujii, T; Hirano, A; Ishihara, H; Ohtsuru, A; Rogounovitch, T; Saenko, V; Yamashita, S, 2003) |
| "Keloid is a fibrotic skin disorder that results in an excessive deposition of extracellular matrix, which is associated with altered-expression of or -responses to TGF-beta in dermal fibroblasts." | 1.32 | IFN-gamma fails to antagonize fibrotic effect of TGF-beta on keloid-derived dermal fibroblasts. ( Hasegawa, T; Nakao, A; Ogawa, H; Sumiyoshi, K; Tsuboi, R, 2003) |
| "Fibroblasts were cultured from nontreated earlobe keloids and burn hypertrophic scars." | 1.32 | Dietary compounds inhibit proliferation and contraction of keloid and hypertrophic scar-derived fibroblasts in vitro: therapeutic implication for excessive scarring. ( Bay, BH; Chan, SY; Lee, ST; Phan, TT; Sun, L, 2003) |
| "Keloid is a benign, well-demarcated area of fibrous tissue overgrowth that extends beyond the original defect." | 1.32 | Keloid in Iraqi patients: a clinicohistopathologic study. ( Al-Dhalimi, MA; Sharquie, KE, 2003) |
| "Keloid is an intricate lesion that is probably modulated by interplay of many genes." | 1.32 | Analysis of differentially expressed genes in keloids and normal skin with cDNA microarray. ( Chen, W; Fu, X; Sheng, Z; Sun, T; Sun, X; Zhao, Z, 2003) |
| "Keloids are benign mesenchymal tumours, usually present at and extending beyond the margins of sites of previous injury." | 1.32 | Topical application of imiquimod 5% cream to keloids alters expression genes associated with apoptosis. ( Berman, B; Jacob, SE; Nassiri, M; Vincek, V, 2003) |
| "Keloids are characterized as an "overexuberant" healing response in which disequilibrium between production and catabolism of extracellular matrix (ECM) occurs." | 1.32 | Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts. ( Akhondzadeh, A; Ann, DK; Duong, HS; Le, AD; Messadi, DV; Wu, Y; Zhang, Q, 2004) |
| "More than half of the normal scars stained minimally for uPAR (<5% staining)." | 1.32 | Expression of urokinase-type plasminogen activator and its receptor in keloids. ( Doerr, TD; Leake, D; Scott, G, 2003) |
| "Keloids are an excessive accumulation of extracellular matrix." | 1.32 | Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts. ( Ann, DK; Bertolami, CN; Kelly, AP; Le, AD; Messadi, DV; Tuan, TL; Wu, Y; Zhang, Q, 2003) |
| "Sphingosine (Sph) is a metabolite product of ceramide that has some different biochemical properties." | 1.32 | Sphingosine may have cytotoxic effects via apoptosis on the growth of keloid fibroblasts. ( Chang, SE; Choi, JH; Kim, KJ; Lim, YJ; Moon, KC; Ro, KH; Sung, KJ, 2004) |
| "Keloids are skin abnormalities that are characterized by excessive deposition of collagen bundles in the dermis." | 1.32 | Tretinoin reverses upregulation of matrix metalloproteinase-13 in human keloid-derived fibroblasts. ( Harii, K; Kitano, Y; Okazaki, M; Uchida, G; Yoshimura, K, 2003) |
| "Biopsy revealed a pattern of breast carcinoma in the skin." | 1.32 | Carcinoma en cuirasse presenting as keloids of the chest. ( Cohen, JB; Mullinax, K, 2004) |
| "Keloids are skin fibrotic conditions characterized by an excess accumulation of extracellular matrix (ECM) components secondary to trauma or surgical injuries." | 1.32 | Crosstalk of hypoxia-mediated signaling pathways in upregulating plasminogen activator inhibitor-1 expression in keloid fibroblasts. ( Ann, DK; Bertolami, CN; Chau, CH; Le, AD; Wu, Y; Zhang, Q, 2004) |
| "We investigated whether PDL treatments induced keloid regression by decreasing growth factor-beta(1) (TGF-beta(1)) induction, thereby reducing fibroblast proliferation and collagen deposition." | 1.32 | Flashlamp pulsed dye laser (PDL) suppression of keloid proliferation through down-regulation of TGF-beta1 expression and extracellular matrix expression. ( Chang, PR; Chen, TH; Huang, HC; Jeng, SF; Kuo, YR; Wang, FS; Yang, KD, 2004) |
| "The appearance of such a scar is more frequent in injuries which have followed a scar process caused as the consequence of a second operation and a disgraceful healing process." | 1.32 | [Prevention and treatment of pathological scars]. ( Cuixart Llopis, S; Magrans Abril, A; Petit Jornet, JM; Teixidó Vidal, X, 2004) |
| "The overall recurrence rate was 26%." | 1.32 | [Postoperative electron beam irradiation therapy for keloid:a follow-up study of 48 patients]. ( Han, CM; He, XJ; Shao, HW; Wang, LC, 2004) |
| "By use of integrated methods to treat keloid, if the wound can be sutured directly, skin grafting should not be adopted." | 1.32 | [Analysis of curative result for keloid with integrated methods]. ( Cen, Y; Cui, ZJ; Liu, XX, 2004) |
| "There were four cases of recurrence." | 1.32 | A surgical approach for earlobe keloid: keloid fillet flap. ( Cho, BH; Eo, SR; Kim, DY; Kim, ES; Kim, KS; Lee, SY, 2004) |
| "Uterine leiomyomas are prevalent estrogen-responsive clonal tumors, but the specific genetic alterations that contribute to their development have not been elucidated." | 1.32 | Reduced dermatopontin expression is a molecular link between uterine leiomyomas and keloids. ( Catherino, WH; Leppert, PC; Nieman, LK; Payson, M; Potlog-Nahari, C; Segars, JH; Stenmark, MH, 2004) |
| "Keloids are proliferative fibrous growths that result from an excessive tissue response to skin trauma." | 1.32 | Genome scans provide evidence for keloid susceptibility loci on chromosomes 2q23 and 7p11. ( Marneros, AG; Norris, JE; Olsen, BR; Reichenberger, E; Watanabe, S, 2004) |
| "Keloids are a major cause of morbidity, and arise after operation, injury, or cutaneous infection." | 1.32 | Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor. ( Arbiser, JL; Brown, LF; Cohen, C; Gira, AK; Washington, CV, 2004) |
| "The umbilical hernia was repaired using a synthetic mesh." | 1.32 | Scar endometriosis developing after an umbilical hernia repair with mesh. ( Craggie, J; Majeski, J, 2004) |
| "Keloid is an intricate lesion that is probably regulated by many genes." | 1.32 | Development of gene microarray in screening differently expressed genes in keloid and normal-control skin. ( Chen, W; Fu, XB; Ge, SL; Sheng, ZY; Sun, XQ; Zhao, ZL; Zhou, G, 2004) |
| "Keloids are benign skin tumors that develop following wounding." | 1.32 | Molecular characterization and expression of p63 isoforms in human keloids. ( Ciarmiello, LF; De Felice, B; Nacca, M; Pinelli, C; Wilson, RR, 2004) |
| "Keloids are characterized as an "over-exuberant" healing response resulting in a disproportionate extracellular matrix (ECM) accumulation and tissue fibrosis." | 1.32 | Activation of NFkappaB signal pathways in keloid fibroblasts. ( Doung, HS; Kelly, AP; Le, AD; Messadi, DV; Reichenberger, E; Tuan, TL; Zhang, Q, 2004) |
| "Biopsies from ten untreated keloids (duration of disease 3 - 30 years) and ten hypertrophic scars (duration of disease 6 - 10 months) and five normal adult skin specimens." | 1.32 | [A study of the abnormalities of human epiderm in keloids and hypertrophic scars]. ( Han, CM; He, XJ; Peng, JP, 2004) |
| "The blood supply to keloids is inadequate, and this persists." | 1.32 | Inadequate blood supply persists in keloids. ( Furuya, E; Oba, S; Ueda, K; Yasuda, Y, 2004) |
| "Because itch and pain are carried by small nerve fibers, abnormal function of these fibers could be an explanation for such phenomena." | 1.32 | Pruritus, pain, and small nerve fiber function in keloids: a controlled study. ( Chan, YH; Goh, CL; Lee, SS; Yosipovitch, G, 2004) |
| "Transforming growth factor beta (TGF beta) is a family of multifunctional cytokines, which play a central role in wound healing and fibrosis." | 1.31 | Genetic susceptibility to keloid disease and transforming growth factor beta 2 polymorphisms. ( Bayat, A; Bock, O; Ferguson, MW; Mrowietz, U; Ollier, WE, 2002) |
| "At 24 weeks, the recurrence rate of excised keloids treated with postoperative imiquimod 5% cream was lower than recurrence rates previously reported in the literature." | 1.31 | Pilot study of the effect of postoperative imiquimod 5% cream on the recurrence rate of excised keloids. ( Berman, B; Kaufman, J, 2002) |
| "An 11-year-old boy with fibrodysplasia ossificans progressiva presented with progressive development of a growing white scar in the central part of the left cornea after excision of a pterygium-like lesion." | 1.31 | Fibrodysplasia ossificans progressiva and corneal keloid. ( Dhooge, MR; Idema, AJ, 2002) |
| "Keloids are typically excluded from palms and soles." | 1.31 | Myofibroblast phenotype and apoptosis in keloid and palmar fibroblasts in vitro. ( Chipev, CC; Hatch, G; Katz, AE; Siegel, DM; Simman, R; Simon, M, 2000) |
| "Keloids are characterized by a net accumulation of collagen." | 1.31 | Elevated interleukin-6 expression in keloid fibroblasts. ( McCauley, RL; Xue, H; Zhang, W, 2000) |
| "The overall recurrence-free response rate was calculated to be 80% for all keloids." | 1.31 | Results of prophylactic irradiation in patients with resected keloids--a retrospective analysis. ( Alfrink, M; Micke, O; Schäfer, U; Schüller, P; Wagner, W; Willich, N, 2000) |
| "Clinically, keloids are most commonly observed in subjects at ages between 10 and 30 years." | 1.31 | Insulin-like growth factor-I (IGF-I)/IGF-I receptor axis and increased invasion activity of fibroblasts in keloid. ( Ishihara, H; Namba, H; Ohtsuru, A; Yamashita, S; Yoshimoto, H, 2000) |
| "Sixteen percent of wounds were repaired with 2-OCA." | 1.31 | Preliminary experience with 2-octylcyanoacrylate in a pediatric emergency department. ( Hick, JL; Resch, KL, 2000) |
| "Hence, it becomes important to treat keloids as a separate entity different from hypertrophic scars and enhancement of Fas-sensitivity could be a promising therapeutic target." | 1.31 | Keloid-derived fibroblasts are refractory to Fas-mediated apoptosis and neutralization of autocrine transforming growth factor-beta1 can abrogate this resistance. ( Chodon, T; Funayama, E; Furukawa, H; Igawa, HH; Sugihara, T, 2000) |
| "Keloids are benign dermal tumors, characterized by overgrowth of lesions, invasiveness beyond the original boundary of the insult, and recurrence of lesions." | 1.31 | Keloid fibroblasts resist ceramide-induced apoptosis by overexpression of insulin-like growth factor I receptor. ( Fujii, T; Fujioka, M; Hirano, A; Ishihara, H; Murakami, R; Namba, H; Ohtsuru, A; Yamashita, S; Yoshimoto, H, 2000) |
| "Unique to humans, keloids are characterized by an accumulation of extracellular matrix components." | 1.31 | Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblasts. ( Chin, GS; Hsu, M; Levinson, H; Liu, W; Longaker, MT; Steinbrech, D, 2000) |
| "Keloid is a dermal fibrotic disease characterized by excessive accumulation of mainly type I collagen in extracellular matrix of the dermis." | 1.31 | Upregulation of HSP47 and collagen type III in the dermal fibrotic disease, keloid. ( Hosokawa, N; Kubota, H; Nagata, K; Naitoh, M; Nishimura, Y; Sawada, M; Shirane, H; Tanaka, T, 2001) |
| "The authors treated 24 keloids of the ear, trunk, face, and genitalia with keloid core excision." | 1.31 | A new surgical treatment of keloid: keloid core excision. ( Baek, RM; Hong, JJ; Lee, Y; Minn, KW, 2001) |
| "Keloids and hypertrophic scars are a result of aberrations of the normal wound healing processes of the skin." | 1.31 | Altered expression of keratins during abnormal wound healing in human skin. ( Gupta, PD; Prathiba, V; Rao, KS, 2001) |
| "Verneuil's disease (hidradenitis suppurativa) is a chronic inflammatory, suppurating and fistulizing disease of apocrine sweat gland-bearing skin." | 1.31 | [Surgical treatment of Verneuil's disease (hidradenitis suppurativa): 15 cases]. ( Destrumelle, N; Dupond, AS; Humbert, P; Lamfichekh, N; Mantion, G; Runser, C, 2001) |
| "Keloids are disfiguring, proliferative scars that represent a pathological response to cutaneous injury." | 1.31 | Investigation of the influence of keloid-derived keratinocytes on fibroblast growth and proliferation in vitro. ( Lim, IJ; Longaker, MT; Phan, TT; Song, C; Tan, WT, 2001) |
| "The keloids were excised extralesionally and the defects were closed with interrupted prolene sutures." | 1.31 | Ear-lobe keloids: treatment by a protocol of surgical excision and immediate postoperative adjuvant radiotherapy. ( Cornes, PG; Glees, JP; Moss, AL; Powell, BW; Ragoowansi, R, 2001) |
| "Keloids are notoriously difficult to treat." | 1.31 | Intralesional cryosurgery using lumbar puncture and/or hypodermic needles for large, bulky, recalcitrant keloids. ( Gupta, S; Kumar, B, 2001) |
| "Keloid and hypertrophic scars are a type of scarring pathology which is characterised by excess collagen deposition produced during the wound healing process." | 1.31 | The role of nitric oxide in the formation of keloid and hypertrophic lesions. ( Cobbold, CA, 2001) |
| "Keloids are a common lesion arising from sites of previous trauma and are a considerable source of morbidity because of continued growth of lesions, pruritus, and physical appearance." | 1.31 | Are keloids really "gli-loids"?: High-level expression of gli-1 oncogene in keloids. ( Arbiser, JL; Cohen, C; DiCarlo, J; Johnson, D; Kim, A; McAlpine, B; McCall, C; McLaughlin, ER; Quinn, AG, 2001) |
| "Keloids are proliferative fibrous growths that result from an excessive tissue response to skin trauma." | 1.31 | Clinical genetics of familial keloids. ( Marneros, AG; Norris, JE; Olsen, BR; Reichenberger, E, 2001) |
| "Proteus syndrome is a rare, congenital hamartomatous syndrome that presents with a wide range of abnormalities." | 1.31 | Cerebriform fibrous proliferation vs. proteus syndrome. ( Boyacioğlu, M; Celebi, MC; Latifoğlu, O; Sari, A; Sarigüney, Y; Uluoğlu, O; Yavuzer, R, 2001) |
| "Keloids are benign lesions that represent an exuberant collagen response to injury." | 1.31 | Treatment of the keloid: what is new? ( Porter, JP, 2002) |
| "Although specific histologic aspects of scars have been well studied, a complete histochemical profile of scars, especially at various stages of evolution, has not been described." | 1.31 | A light microscopic and immunohistochemical evaluation of scars. ( Bergfeld, WF; House, NS; Kamath, NV; Ormsby, A, 2002) |
| "Keloids and hypertrophic scars are significant symptomatic clinical problems characterized by excess collagen." | 1.31 | Alterations in fibroblast alpha1beta1 integrin collagen receptor expression in keloids and hypertrophic scars. ( Gardner, H; Panos, R; Rudolph, R; Szulgit, G; Tenenhaus, M; Wandel, A, 2002) |
| "Keloids are characterized by the deposition of excessive extracellular-matrix collagen by abnormal fibroblasts in response to cutaneous injury." | 1.31 | Differences in collagen production between normal and keloid-derived fibroblasts in serum-media co-culture with keloid-derived keratinocytes. ( Bay, BH; Huynh, HT; Lee, ST; Lim, IJ; Longaker, MT; Phan, TT; Qi, R, 2002) |
| "Hypertrophic scar derived fibroblasts showed no change." | 1.31 | The effects of sialic acid on the gene expression of fibrillar collagens: different changes in normal and fibrotic scar derived fibroblasts. ( Aalto, J; Haataja, S; Kössi, J; Laato, M; Niinikoski, J; Peltonen, J, 2001) |
| "Earlobe keloids are benign, fibrous proliferations that show a high rate of recurrence of up to 80% following surgical excision." | 1.31 | [Keloid of the earlobe after ear piercing. Not only a surgical problem]. ( Büttemeyer, R; Mall, JW; Müller, JM; Pollmann, C, 2002) |
| "Keloids are relatively common sequelae of trauma to the skin of the head and neck." | 1.30 | Facial keloids. A 15-year experience. ( Davis, PT; Lindsey, WH, 1997) |
| "Severe cases of nuchal AM may precede acne keloidalis nuchae (AKN)." | 1.30 | Prevalence of acne keloidalis nuchae in football players. ( Gonin, R; Hanke, CW; Knable, AL, 1997) |
| "Six patients with previously untreated keloids were studied." | 1.30 | Major suppression of pro-alpha1(I) type I collagen gene expression in the dermis after keloid excision and immediate intrawound injection of triamcinolone acetonide. ( diLeonardo, M; Kauh, YC; Mondragon, G; Rouda, S; Tan, EM; Tokarek, R; Tuan, RS, 1997) |
| "We determined the rate of recurrence after excision alone (n = 43) and postoperative injection with triamcinolone acetonide (TAC; n = 65) or interferon alfa-2b (IFN-alpha 2b; n = 16)." | 1.30 | Recurrence rates of excised keloids treated with postoperative triamcinolone acetonide injections or interferon alfa-2b injections. ( Berman, B; Flores, F, 1997) |
| "Keloids are clinically vexacious scars characterized by a high recurrence rate after excision alone (50-100%)." | 1.30 | Postoperative interstitial radiotherapy of keloids by iridium 192: a retrospective study of 46 treated scars. ( Bedane, C; Bonnafoux-Clavere, A; Bonnetblanc, JM; Clavere, P; Rousseau, J, 1997) |
| "Ideal conditions for best scarring include: accurate apposition of wound edges; sutures under minimal tension; everted skin edges; placing the wound in 'Langer's lines' or lines of election; adequately supporting the wound; ensuring the wound is free from infection or haematoma." | 1.30 | Scars. Can they be minimised? ( Burke, M, 1998) |
| "Unusual variants of dermatofibroma that exhibit various epidermal changes or different cellular composition have been described." | 1.30 | Keloidal dermatofibroma: report of 10 cases of a new variant. ( Chan, HL; Hu, S; Kuo, TT, 1998) |
| "Cutaneous leiomyosarcoma is a rare tumour, accounting for 2." | 1.30 | Recurrent cutaneous leiomyosarcoma. ( Balducci, A; Innocenzi, D; Ribuffo, D; Scuderi, N; Valeriani, M, 1998) |
| "Keloid is a tissue with an excessive accumulation of collagen." | 1.30 | Altered posttranslational modifications of collagen in keloid. ( Katz, EP; Marshall, MK; Tanzawa, H; Uzawa, K; Yamauchi, M; Yeowell, HN, 1998) |
| "In monolayer culture, both normal and scar fibroblasts continued to express high levels of mRNA for pro alpha 1(I) and pro alpha 1(III) collagens." | 1.30 | Distinct patterns of collagen gene expression are seen in normal and keloid fibroblasts grown in three-dimensional culture. ( Ishikawa, O; Miyachi, Y; Sato, M, 1998) |
| "Surgical scars and pathological scar reactions were stained immunohistochemically for tryptase to identify mast cells." | 1.30 | Mast cells in pathological and surgical scars. ( Baldwin, H; Beer, TW; Gallagher, PJ; West, L; Wright, DH, 1998) |
| "Keloid is a dermal fibroproliferative tissue of unknown etiology." | 1.30 | Overexpression of insulin-like growth factor-1 (IGF-I) receptor and the invasiveness of cultured keloid fibroblasts. ( Akino, K; Fujii, T; Ishihara, H; Ito, M; Kuroda, H; Murakami, R; Namba, H; Ohtsuru, A; Yamashita, S; Yoshimoto, H, 1999) |
| "Histologically, keloids are composed of excessive collagen with an abnormally large number of partially or totally occluded microvessels." | 1.30 | Hypoxia upregulates VEGF production in keloid fibroblasts. ( Chau, D; Chin, G; Gittes, GK; Lee, T; Longaker, MT; Mehrara, BJ; Rowe, NM; Saadeh, PB; Steinbrech, DS, 1999) |
| "Transforming growth factor beta (TGF-beta) has been implicated in the pathogenesis of keloids." | 1.30 | Expression of transforming growth factor beta 1, 2, and 3 proteins in keloids. ( Chau, D; Chin, GS; Gittes, GK; Kim, WJ; Lee, TY; Longaker, MT, 1999) |
| "As a surgical treatment for keloids, we have been using the intralesional technique which we think gives better results." | 1.30 | [Hypertrophic scars and keloids: which therapeutic options today?]. ( Egloff, DV; Gailloud-Matthieu, MC; Raffoul, W, 1999) |
| "Keloid formation and endometrial carcinoma are both associated with similar cytokine abnormalities and as such, we hypothesize that this is a previously unreported paraneoplastic phenomenon." | 1.30 | Eruptive paraneoplastic keloids. ( Alam, M; Coppa, LM; Longley, BJ; Stiller, MJ, 1999) |
| "In the childhood population, atopic eczema and tinea capitis were the most frequent dermatoses, comprising 63% of diagnoses recorded." | 1.30 | A study of the spectrum of skin disease occurring in a black population in south-east London. ( Child, FJ; Du Vivier, AW; Fuller, LC; Higgins, EM, 1999) |
| "Keloids are exuberant scars, in which collagen, fibronectin and glycosaminoglycans are overdeposited." | 1.30 | Biochemical and dynamic studies of collagen from human normal skin and keloid tissue. ( Prathiba, V; Suryanarayanan, M, 1999) |
| "Keloid and hypertrophic scars are relatively frequent not wanted consequences of surgical treatment." | 1.30 | [Treatment of keloids and hypertrophic scars with cryotherapy]. ( Jaros, E; Klein, L; Príborský, J, 1999) |
| "The surgery and management of scars is a protracted and staged process that includes preparation of the skin through hygienic measures, scar softening (if indicated) with steroids, massage and pressure dressings, skilled execution of the surgical plan, and thorough postoperative wound care." | 1.30 | Scar modification. Techniques for revision and camouflage. ( Horswell, BB, 1998) |
| "In mature scar tissue the distribution of HA resembled that of normal uninjured tissue, but the layer of HA was thinner." | 1.29 | The distribution of hyaluronan in human skin and mature, hypertrophic and keloid scars. ( Bertheim, U; Hellström, S, 1994) |
| "Tranilast was found to inhibit collagen synthesis in a dose-dependent manner to a maximum of 55% at 300 microM during 48 h of treatment; the synthesis of type I and type III collagens was equally affected." | 1.29 | Tranilast, a selective inhibitor of collagen synthesis in human skin fibroblasts. ( Murad, S; Nishikawa, T; Pinnell, SR; Tajima, S; Yamada, H, 1994) |
| "To investigate dermatography as a treatment for cleft lip and palate." | 1.29 | Dermatography as an adjunctive treatment for cleft lip and palate patients. ( van der Dussen, MF; van der Velden, EM, 1995) |
| "Morphologic changes in steroid-treated keloids were established using light and electron microscopy." | 1.29 | Histomorphologic changes in keloids treated with Kenacort. ( Boyadjiev, C; Mazgalova, J; Popchristova, E, 1995) |
| " As the dosage of radiation increased, the numbers of viable cells in irradiated groups were remarkably decreased exponentially, with no significant difference between normal and keloid cell lines." | 1.29 | Effects of x-irradiation on survival and extracellular matrix gene expression of cultured keloid fibroblasts. ( Jung, JB; Kim, OB; Lee, KS; Ro, YJ; Ryoo, YW; Song, JY, 1994) |
| "Kaposi's sarcoma is a unique neoplasm which has emerged as an important element of AIDS in homosexuals but not in others at high risk for AIDS." | 1.29 | Keloidal Kaposi's sarcoma: report of three patients. ( Cohen, PJ; Janniger, CK; Lambert, WC; Melczer, MM; Schwartz, RA; Spicer, MS, 1994) |
| "Keloid and hypertrophic scars are fibrous growths characterized by overabundant collagen deposition." | 1.29 | Modulation of collagen synthesis by transforming growth factor-beta in keloid and hypertrophic scar fibroblasts. ( Nichter, LS; Nimni, ME; Reinisch, J; Tuan, TL; Wellisz, T; Younai, S, 1994) |
| "In the treatment of keloids surgical excision followed by radiation therapy provides the highest reported control rates of 72% to 92%." | 1.29 | Keloids treated with excision followed by radiation therapy. ( Anscher, M; Klumpar, DI; Murray, JC, 1994) |
| "Linear keloids are an unusual manifestation." | 1.29 | Linear keloids resulting from abuse of anabolic androgenic steroid drugs. ( Scott, AM; Scott, MJ, 1994) |
| "Thirteen patients with 17 scars and keloids were admitted to the study." | 1.29 | [Treatment of keloids and hypertrophic scars. Pilot study with intralesional Lipotalon injections]. ( Stark, GB, 1994) |
| "Severe tricuspid regurgitation was demonstrated by echocardiography with a certain calcification in the cardiac shadow on chest radiogram." | 1.29 | [Heart failure due to severe myocardial calcification--a rare complication after irradiation on the chest wall]. ( Maida, K; Takahashi, S; Tanaka, S; Yokoyama, H, 1993) |
| "Traditional treatment of keloids by surgery or surgery combined with other techniques has met with limited success." | 1.29 | Sternal keloids: successful treatment employing surgery and adjunctive radiation. ( Mincer, FR; Ship, AG; Weiss, PR; Wolkstein, W, 1993) |
| "Keloids are disfiguring deformities that occur after trauma or wounding of the skin, most commonly among blacks." | 1.29 | Exuberant keloidal formation. ( Abrams, BJ; Benedetto, AV; Humeniuk, HM, 1993) |
| "This recurrence rate is about the same as for external radiotherapy, but we prefer our method for practical reasons (cost, equipment, radiobiology, technique)." | 1.29 | The treatment of 783 keloid scars by iridium 192 interstitial irradiation after surgical excision. ( Amar, A; Azaloux, H; Escarmant, P; Francois, H; G'Baguidi, R; Gosserez, O; Michel, M; Moris, A; Ratoanina, JL; Zimmermann, S, 1993) |
| "Numerous approaches are used to treat keloids, but none is ideal for all scars and recurrence after treatment is frequent." | 1.29 | Use of cryotherapy in the treatment of keloids. ( Bono, R; Rossi, G; Rusciani, L, 1993) |
| "The treatments did not result in scarring or permanent pigment changes other than the ones intended." | 1.29 | Laser treatment of tattoos in darkly pigmented patients: efficacy and side effects. ( Anderson, RR; DeCoste, SD; Duke, D; Gonzalez, E; Grevelink, JM; van Leeuwen, RL, 1996) |
| "A keloid is a pathological overgrowth of scar expanding beyond the boundaries of the initiating skin wound." | 1.29 | Increased proliferation in keloid fibroblasts wounded in vitro. ( Banes, AJ; Calderon, M; Lawrence, WT, 1996) |
| "Basal cell carcinoma is the commonest malignant neoplasm of the skin." | 1.29 | Keloidal basal cell carcinoma. A new clinicopathological variant of basal cell carcinoma. ( Escalonilla, P; Fariña, MC; Martín, L; Piqué, E; Requena, L, 1996) |
| "Excessive scar contracture by wound fibroblasts can have devastating consequences, ranging from body disfigurement to joint immobility." | 1.29 | Role of growth factors in scar contraction: an in vitro analysis. ( Nichter, L; Nimni, ME; Tuan, TL; Venters, G; Vu, S; Younai, S, 1996) |
| "Keloids are characterized by an overabundant deposition of collagen, and they recur frequently following excision." | 1.29 | The effect of TGF-beta on keloid fibroblast proliferation and collagen synthesis. ( Bettinger, DA; Cohen, IK; Diegelmann, RF; Yager, DR, 1996) |
| "Keloids are pathological lesions characterized by enhanced expression of extracellular matrix molecules including fibronectin." | 1.29 | DNA binding proteins from keloid fibroblasts form unique complexes with the human fibronectin promoter. ( Eriksson, E; Oliver, N; Sible, JC, 1996) |
| "However, the results in treating keloid are variable." | 1.29 | Silicone cream occlusive dressing--a novel noninvasive regimen in the treatment of keloid. ( Chang, CH; Chen, JS; Chiu, HC; Lin, LJ; Liu, CC; Wong, TW, 1996) |
| "Keloids are collagenous lesions acquired as a result of abnormal wound heating." | 1.29 | Apoptosis, necrosis, and proliferation: possible implications in the etiology of keloids. ( Appleton, I; Brown, NJ; Willoughby, DA, 1996) |
| "18 keloids were completely cured, 9 improved, 2 showed only minimum change, the treatment had to be given up in two patients." | 1.29 | [Treatment of keloids (review of the literature, therapeutic suggestions)]. ( Bánfalvi, T; Boér, A; Oberna, F; Remenár, E, 1996) |
| "In general, the SC on the scars of deeper wounds in the dermis took longer to normalize functionally than the SC on the scars of superficial wounds, especially on the high compared with the abdomen." | 1.29 | Functional analyses of the stratum corneum in scars. Sequential studies after injury and comparison among keloids, hypertrophic scars, and atrophic scars. ( Ohi, T; Sasai, S; Suetake, T; Tagami, H; Zhen, YX, 1996) |
| "Treatment of keloids is often disappointing and sometime quite difficult to manage." | 1.29 | [Treatment of keloid with intralesional bleomycin]. ( Bodokh, I; Brun, P, 1996) |
| "Considering that hypertrophic scar and keloid are conditions characterized by abnormal cell proliferation and excessive collagen accumulation accompanied with itch and pain, these results suggest that tranilast is useful as a therapeutic drug for hypertrophic scars and keloids." | 1.28 | [Effect of tranilast, an anti-allergic drug, on carrageenin-induced granulation and capillary permeability in rats]. ( Hamano, S; Ichikawa, K; Kikuchi, S; Komatsu, H; Miyata, H; Suzawa, H; Tsuchiya, O; Yamada, K, 1992) |
| " The possibility of altered gene dosage was eliminated because chromosome content, G-banding patterns, and fibronectin gene content of keloid fibroblasts were all found to be normal." | 1.28 | Fibronectin gene transcription is enhanced in abnormal wound healing. ( Babu, M; Diegelmann, R; Oliver, N, 1992) |
| "Normal scar fibroblasts showed greater capacity for generating hyaluronate-derived partial degradation products." | 1.28 | Binding and internalization of hyaluronate by human cutaneous fibroblasts. ( Berg, S; Bertolami, CN; Messadi, DV, 1992) |
| "When indomethacin was added with PMA the delayed peak appeared in normal fibroblasts." | 1.28 | Keloid fibroblasts are refractory to inhibition of DNA synthesis by phorbol esters. Altered response is accompanied by reduced sensitivity to prostaglandin E2 and altered down-regulation of phorbol ester binding sites. ( Myles, ME; Russell, JD; Russell, SB; Smith, JC; Trupin, JS, 1992) |
| "Here we report our method of treating recurrent keloid and hypertrophic scars." | 1.28 | Intra- and postoperative steroid injections for keloids and hypertrophic scars. ( Tang, YW, 1992) |
| "No keloid has ever been noted to recur before epithelial migration is complete." | 1.28 | An approach to management of keloids. ( Shaw, GY; Stucker, FJ, 1992) |
| "Keloids are benign cutaneous tumours characterized by excess deposition of collagen, specifically type I collagen." | 1.28 | Endothelial cell growth factor and heparin regulate collagen gene expression in keloid fibroblasts. ( Peltonen, J; Tan, EM, 1991) |
| "One patient had no recurrence of her keloid after carbon dioxide laser excision, 9 patients required steroids to suppress recurrences, and 13 patients were considered failures." | 1.28 | The effect of carbon dioxide laser surgery on the recurrence of keloids. ( Norris, JE, 1991) |
| "Pieces of keloid, hypertrophic scar or normal human skin were placed in subcutaneous pockets of athymic nude mice and left for various times up to 246 days." | 1.28 | Implants of keloid and hypertrophic scars into the athymic nude mouse: changes in the glycosaminoglycans of the implants. ( Kischer, CW; Pindur, J; Shetlar, CL; Shetlar, MR, 1991) |
| " We believe the TT route is a relatively safe approach for oxygen administration and a promising method of improving patient compliance." | 1.28 | Transtracheal delivery of oxygen: efficacy and safety for long-term continuous therapy. ( Dauber, JH; Ferson, PF; Hoffman, LA; Johnson, JT; Mazzocco, MC; Sciurba, FC; Wesmiller, SW, 1991) |
| "Keloids are rapidly resolved with the use of flurandrenolide tape covered with positive-pressure chin-strap dressings." | 1.28 | The prevention and management of postdermabrasion complications. ( Fulton, JE, 1991) |
| "The treatment of hypertrophic scars and keloids is a problem that has not yet been satisfactorily solved." | 1.28 | [Cryosurgical treatment of hypertrophic scars and keloids]. ( Orfanos, CE; Zouboulis, CC, 1990) |
| " Interferon gamma can safely be administered intralesionally once per week up to a dosage of 0." | 1.28 | Intralesional interferon gamma treatment for keloids and hypertrophic scars. ( East, CA; Jaffe, HS; Larrabee, WF; Peterson, KE; Stephenson, C, 1990) |
| "Eight of the nine keloids have recurred to their original or close to original size as early as 10 months following treatment and as late as 22 months." | 1.28 | Failure of carbon dioxide laser excision of keloids. ( Apfelberg, DB; Lash, H; Maser, MR; White, DN, 1989) |
| "The array of malignant neoplasms does not suggest an etiology or pathogenesis in common." | 1.28 | Keloids and neoplasms in the Rubinstein-Taybi syndrome. ( Miller, RW; Rubinstein, JH; Siraganian, PA, 1989) |
| "A case of extensive scarring of the floor of the mouth mucosa is reported." | 1.28 | A keloidal scar of the floor of the mouth and its associations. Case report. ( Ow, RK, 1989) |
| "Two hypertrophic scars and their adjacent skin cell lines were evaluated by the ELISA method for FN and a micro Lowry assay for PR." | 1.28 | Increased fibronectin production by cell lines from hypertrophic scar and keloid. ( Holubec, H; Jones, M; Kischer, CW; Pindur, J; Scuderi, P; Ulreich, JB; Wagner, HN, 1989) |
| "Pieces of hypertrophic scars and keloids were implanted into subcutaneous pockets of nude (athymic) mice and carried for varying times up to 246 days." | 1.28 | Implants of hypertrophic scars and keloids into the nude (athymic) mouse: viability and morphology. ( Kischer, CW; Pindur, J; Shetlar, CL; Shetlar, MR, 1989) |
| "The mean time to recurrence was 12." | 1.28 | Radiation therapy following keloidectomy: a 20-year experience. ( Kovalic, JJ; Perez, CA, 1989) |
| "Hypertrophic scars and keloids appear to be unique to humans since animals are not known to form these lesions." | 1.28 | Use of nude (athymic) mice for the study of hypertrophic scars and keloids: vascular continuity between mouse and implants. ( Kischer, CW; Pindur, J; Sheridan, D, 1989) |
| "Hypertrophic scar and keloid are diagnoses based on clinical symptoms." | 1.28 | [Treatment methods of keloid and hypertrophic scar formation]. ( Hahn, T; Pilegaard, J; Wester, JU, 1989) |
| "Silicone gel is effective in the treatment of keloid scars." | 1.28 | Silicone gel in the treatment of keloid scars. ( Mercer, NS, 1989) |
| "Hypertrophic scar and keloid demonstrated heavy deposition of FN, which conformed to the nodular characteristics of the lesions." | 1.27 | Fibronectin (FN) in hypertrophic scars and keloids. ( Hendrix, MJ; Kischer, CW, 1983) |
| "These scars have been treated in a variety of ways with the laser, and the results, which have been good, are reported." | 1.27 | Argon and carbon dioxide laser treatment of hypertrophic and keloid scars. ( Cromwell, TA; Henderson, DL; Mes, LG, 1984) |
| "Two patients with progressive systemic sclerosis (PSS) developed keloidal-like nodules within areas of thickened skin." | 1.27 | Nodular (keloidal) scleroderma. ( Berger, TG; Butler, DF; James, WD; Tuffanelli, DL, 1984) |
| "Hypertrophic scarring and keloids are frequent sequelae following trauma." | 1.27 | Pressure garments in the prevention and treatment of keloids. ( Lee, ST; Ng, CL; Wong, KL, 1983) |
| "One hundred and eighty cases of uterine fibroids out of the two hundred treated in a gynaecological unit in a 7-year period are reviewed." | 1.27 | Management of uterine fibroids at the University of Benin Teaching Hospital. ( Ihejerika, IJ; Omu, AE; Tabowei, G, 1984) |
| "Only 1 recurrence developed in a follow-up of twelve to sixty-two months." | 1.27 | The treatment of earlobe keloids by surgical excision and postoperative triamcinolone injection. ( Press, BH; Shons, AR, 1983) |
| "Significant scarring is a potential sequela of the second degree burns produced by argon or carbon dioxide laser surgery, and is particularly a risk for children." | 1.27 | Laser surgery for children. ( Brauner, GJ; Schliftman, A, 1987) |
| "Several methods for the treatment of scar keloids have been reported." | 1.27 | Effectiveness of silastic sheet coverage in the treatment of scar keloid (hypertrophic scar) ( Ohmori, S, 1988) |
| "Keloids are benign dermal tumors that form during an abnormal wound-healing process in genetically susceptible individuals." | 1.27 | Reduced growth-factor requirement of keloid-derived fibroblasts may account for tumor growth. ( Rodríguez-Eaton, S; Russell, JD; Russell, SB; Trupin, JS; Trupin, KM, 1988) |
| "Hypertrophic scars and keloids still present problems in both white and pigmented skin." | 1.27 | A protocol for the treatment of hypertrophic scars and keloids. ( Bos, MY; Bronkhorst, FB; Nicolai, JP; Smale, CE, 1987) |
| "Patients with a wide scar may complain of having a "keloid," yet have a hypertrophic or a wide spread scar." | 1.27 | Wide spread scars, hypertrophic scars, and keloids. ( Rudolph, R, 1987) |
| "We report on the treatment of keloids and scars by means of topical application and injection of active substances." | 1.27 | [Conservative therapy of scars and wrinkles]. ( Landes, E, 1987) |
| "Molluscum contagiosum is an infectious disease of the skin, found primarily on the thighs and genitalia." | 1.27 | Keloid scars as a result of CO2 laser for molluscum contagiosum. ( Friedman, M; Gal, D, 1987) |
| "Atrophic scars resulted after 1 to 8 treatments." | 1.27 | [Treatment of keloids by cryotherapy]. ( Mende, B, 1987) |
| "The development of suppuration and sinus tract formation within previously well developed keloidal scars is a rare event, predominantly occurring in the beard, neck, and presternal areas of black men." | 1.27 | Suppurative keloidosis in a black woman. ( Lawson, W; Novick, NL; Schwartz, IS, 1986) |
| "Free grafts." | 1.27 | [Indications for free transplants for scar correction in the area of the head and neck]. ( Staindl, O, 1986) |
| "A report is given on the treatment of keloids and hypertrofic scars using an argon laser." | 1.27 | Treatment of keloids and hypertrophic scars with an argon laser. ( Hulsbergen Henning, JP; Roskam, Y; van Gemert, MJ, 1986) |
| "Keloids are histologically characterized by an abundance of the extracellular matrix of connective tissue." | 1.27 | Biochemical composition of the connective tissue in keloids and analysis of collagen metabolism in keloid fibroblast cultures. ( Abergel, RP; Chu, ML; Lask, G; Matsuoka, LY; Meeker, CA; Minor, RR; Pizzurro, D; Uitto, J, 1985) |
| "Hypertrophic scars contain highly pleomorphic cells, including many from the erythrocytic series which have been extravasated." | 1.27 | Wave-length dispersive microprobe analysis of coated samples of bulk tissues. ( Kischer, CW; Teska, TM, 1985) |
| "Scar hypertrophy is most likely in that part of the scar overlying the body of the sternum and particularly in the female." | 1.27 | The behaviour of presternal scars in a fair-skinned population. ( Cory-Pearce, R; Elliot, D; Rees, GM, 1985) |
| "The syndrome of torticollis, keloids, cryptorchidism and renal dysplasia was described by Goeminne (1968) in a large family, and listed as X-linked incomplete dominant by McKusick (1978; No." | 1.26 | Gene mapping and serendipity. The locus for torticollis, keloids, cryptorchidism and renal dysplasia (31430, Mckusick) is at Xq28, distal to the G6PD locus. ( Fraccaro, M; Zuffardi, O, 1982) |
| "In other situations, as in the treatment of keloids, physicians may wish to introduce drugs known to reduce scar formation into the biologic environment in which wound healing ensues." | 1.26 | Wound healing: a review. IV. Systemic medications affecting wound healing. ( Pollack, SV, 1982) |
| "A cystic parathyroid adenoma was identified during surgery and was, on microscopic examination, composed of oxyphil cells rich in mitochondria." | 1.26 | Hyperparathyroidism due to a cystic parathyroid adenoma after irradiation of the neck. ( Eisenberg, H; Elias, AN; Fishman, A; Gordon, M; Pezzlo, F; Valenta, LJ, 1982) |
| "A report is given on the treatment of keloids and hypertrophic scars using ordinary zinc tape." | 1.26 | Treatment of keloids and hypertrophic scars with adhesive zinc tape. ( Bartholdson, L; Hallmans, G; Söderberg, T, 1982) |
| "Hypertrophic scars and keloids are often the sequelae of deep injury to the skin of man." | 1.26 | Hypertrophic scars and keloids: a review and new concept concerning their origin. ( Chvapil, M; Kischer, CW; Shetlar, MR, 1982) |
| "The results of treating hypertrophic scars with urea preparations are also to be evaluated optimistically." | 1.26 | [Formation and treatment of pathologic scars--clinical and micromorphologic investigations (author's transl)]. ( Auböck, L; Bayer, U; Kerl, H, 1981) |
| "Earlobe keloids had recurrence rates similar to those noted for the series of a whole." | 1.26 | Treatment of keloids by combined surgical excision and immediate postoperative X-ray therapy. ( Barsa, JM; Gillooley, JF; Ollstein, RN; Siegel, HW, 1981) |
| "It is never found in the fully mature scars." | 1.26 | Structure of the collagen nodule from hypertrophic scars and keloids. ( Brody, GS; Kischer, CW, 1981) |
| "Elastin fibers were noted at sites where they must have been formed de novo." | 1.26 | Elastin fibers in scar tissue. ( Bhangoo, KS; Connelly, JR; Quinlivan, JK, 1976) |
| "Indications for radiotherapy of benign dermatoses have decreased markedly during the past decades." | 1.26 | [Roentgen therapy of dermatoses: indications and hazards]. ( Goldschmidt, H, 1978) |
| "2) Raised and widened scars were few at the site of the incision parallel to the cleavage lines but there were seen often at the site of the perpendicular incision." | 1.26 | Postoperative scars and cleavage lines. ( Azumi, Y; Motegi, K; Ueno, T, 1977) |
| "A treatment for keloid overgrowth of a scar and a simple technique for rapid but careful closure of the skin have also been presented." | 1.26 | Basic Operative technique. ( Monroe, CW, 1977) |
| "There is a type of keloid that tends to suppuration." | 1.26 | The suppurative keloid. ( Onwukwe, MF, 1978) |
| "Particular care was taken to separate scar tissue from adjacent normal dermis." | 1.26 | Collagen polymorphism in pathologic human scars. ( Meigel, WN; Spier, W; Weber, L, 1978) |
| "Keloids are medically benign, but often psychologically and cosmetically malignant lesions." | 1.26 | Surgical treatment of keloids secondary to ear piercing. ( Kelly, AP, 1978) |
| " Collagen synthesis was suppressed only by long-term administration of massive systemic doses of a sustained release form of methylprednisolone (Depo-Medrol)." | 1.26 | Effect of corticosteroids on collagen synthesis. ( Cohen, IK; Diegelmann, RF; Johnson, ML, 1977) |
| "Four mucous cysts of the lip were treated successfully by the cryoprobe without any visible or palpable scar." | 1.25 | Cryosurgery in dermatologic office practice: special reference to dermatofibroma and mucous cyst of the lip. ( Spiller, RF; Spiller, WF, 1975) |
| "As hypertrophic and keloid scars are formed essentially by fibrous connective tissue, the therapeutic response of an enzyme with specific action on mucopolysaccharides of the fundamental connective tissue substance (Thiomucase) was studied." | 1.25 | [Treatment of hypertrophic and keloid cicatrices with thiomucase]. ( Donati, L; Taidelli Palmizi, GA, 1975) |
| "The results of treatment of keloids are still very disappointing." | 1.25 | Keloids in Ibadan. ( Oluwasanmi, JO, 1974) |
| "Hypothyroidism was present in eight (6." | 1.25 | Long-term follow-up of surgically treated thyrotoxic patients. ( McNeill, AD; Thomson, JA, 1968) |
| "A hypertrophic scar results from the removal or destruction of the cutaneous appendages (hair follicles, oil and sweat glands and ducts); whereas a keloid is an idiosyncratic response without regard to damage of the appendages." | 1.24 | Surgical planing of the skin; dichlorotetrafluoro-ethane as a freezing agent. ( AYRES, S; LUIKART, R; WILSON, JW, 1956) |
Research
Studies (3,808)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 921 (24.19) | 18.7374 |
| 1990's | 397 (10.43) | 18.2507 |
| 2000's | 728 (19.12) | 29.6817 |
| 2010's | 1097 (28.81) | 24.3611 |
| 2020's | 665 (17.46) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Yue, S | 1 |
| Ju, M | 2 |
| Naval, S | 1 |
| Nien, MS | 1 |
| Cheng, WP | 1 |
| Feng, J | 2 |
| Cui, YY | 1 |
| Yuan, R | 3 |
| Dai, X | 2 |
| Li, Y | 21 |
| Li, C | 10 |
| Liu, L | 17 |
| Naik, PP | 1 |
| Wan, J | 1 |
| He, XL | 1 |
| Jian, QC | 1 |
| Fan, ZF | 1 |
| Shi, Y | 8 |
| Luo, LF | 2 |
| Nestor, MS | 1 |
| Berman, B | 28 |
| Fischer, DL | 1 |
| Han, H | 1 |
| Gade, A | 1 |
| Arnold, D | 1 |
| Lawson, A | 1 |
| Huang, S | 2 |
| Liao, J | 1 |
| Luo, X | 4 |
| Liu, F | 4 |
| Shi, G | 1 |
| Wen, W | 1 |
| Nyika, DT | 1 |
| Khumalo, NP | 2 |
| Bayat, A | 65 |
| Rath, M | 1 |
| Pitiot, A | 1 |
| Kirr, M | 1 |
| Fröhlich, W | 1 |
| Plosnita, B | 1 |
| Schliep, S | 1 |
| Bauerschmitz, J | 2 |
| Baur, AS | 1 |
| Ostalecki, C | 1 |
| Moravvej, H | 4 |
| Memariani, H | 3 |
| Memariani, M | 3 |
| Hawash, AA | 1 |
| Ingrasci, G | 1 |
| Nouri, K | 7 |
| Yosipovitch, G | 5 |
| Tolkachjov, SN | 1 |
| Tirgan, MH | 7 |
| Uitto, J | 27 |
| Deng, Z | 6 |
| Subilia, M | 1 |
| Chin, IL | 1 |
| Hortin, N | 2 |
| Stevenson, AW | 4 |
| Wood, FM | 7 |
| Prêle, CM | 2 |
| Choi, YS | 2 |
| Fear, MW | 6 |
| Yu, Y | 8 |
| Wu, H | 8 |
| Zhang, Q | 19 |
| Ogawa, R | 67 |
| Fu, S | 2 |
| Searle, T | 1 |
| Al-Niaimi, F | 2 |
| Ali, FR | 2 |
| Guttman-Yassky, E | 3 |
| Diaz, A | 3 |
| Pavel, AB | 3 |
| Tan, K | 2 |
| He, H | 3 |
| Xu, H | 9 |
| Cueto, I | 3 |
| Krueger, JG | 4 |
| Wang, CH | 1 |
| Shan, MJ | 1 |
| Liu, H | 24 |
| Hao, Y | 14 |
| Song, KX | 2 |
| Wu, HW | 1 |
| Meng, T | 4 |
| Feng, C | 6 |
| Qi, Z | 6 |
| Wang, Z | 18 |
| Wang, YB | 3 |
| Goodman, GJ | 1 |
| Lei, TC | 2 |
| Reddy, DN | 1 |
| Rossi, NA | 1 |
| Ohlstein, JF | 1 |
| Coblens, O | 1 |
| Jin, M | 2 |
| Luo, Y | 4 |
| Jin, Z | 9 |
| Pi, L | 2 |
| Hua, Z | 1 |
| Wei, P | 1 |
| Jiang, L | 3 |
| Shi, X | 4 |
| Wang, M | 13 |
| Chen, H | 11 |
| Gao, N | 1 |
| Lu, L | 7 |
| Ma, X | 8 |
| Liu, Z | 15 |
| Yang, S | 10 |
| Han, G | 2 |
| Kim, S | 6 |
| Lee, SE | 1 |
| Yi, S | 2 |
| Jun, S | 1 |
| Yi, YS | 1 |
| Nagar, H | 2 |
| Kim, CS | 2 |
| Shin, C | 1 |
| Yeo, MK | 1 |
| Kang, YE | 1 |
| Oh, SH | 2 |
| Wanjala, NF | 1 |
| Joseph, G | 1 |
| Anthony, M | 1 |
| Primus, O | 1 |
| Ogeng'o, JJ | 1 |
| Anzala, O | 2 |
| Dohil, I | 1 |
| Agak, GW | 2 |
| Wang, J | 19 |
| Shen, J | 2 |
| Ramadan, H | 1 |
| Saber, M | 1 |
| Salah, M | 1 |
| Samy, N | 1 |
| Schaffrick, L | 1 |
| Ding, J | 4 |
| Kwan, P | 1 |
| Tredget, EE | 4 |
| Zhou, B | 3 |
| Gao, Z | 21 |
| Liu, W | 30 |
| Wu, X | 25 |
| Wang, W | 19 |
| Onoufriadis, A | 3 |
| Hsu, CK | 9 |
| Hong, YK | 3 |
| Lin, YC | 3 |
| McGrath, JA | 4 |
| Dong, X | 8 |
| Jin, X | 3 |
| Melton, PE | 1 |
| Moses, EK | 1 |
| Wallace, HJ | 3 |
| Rea, S | 1 |
| Danielsen, PL | 2 |
| Alghamdi, M | 3 |
| Borowczyk, J | 1 |
| Manzur, M | 2 |
| Seong, YW | 1 |
| Kim, JH | 3 |
| Ok, YJ | 1 |
| Oh, SJ | 2 |
| Choi, JS | 1 |
| Lee, JS | 5 |
| Moon, HJ | 1 |
| Harsono, AD | 1 |
| Prasetyono, TOH | 1 |
| Dilogo, IH | 1 |
| Piccolo, D | 2 |
| Crisman, G | 2 |
| Bovani, B | 1 |
| Gennai, A | 1 |
| Melfa, F | 1 |
| Clementoni, MT | 2 |
| Conforti, C | 2 |
| Liu, Y | 44 |
| Li, Z | 15 |
| Hu, J | 6 |
| Zhan, S | 2 |
| Wang, L | 13 |
| Su, X | 3 |
| Nejat, AH | 1 |
| Hamdan, S | 1 |
| Abrego, I | 1 |
| Lindsey, JT | 1 |
| Vitter, R | 1 |
| Dohi, T | 11 |
| Cho, H | 1 |
| Kamegai, M | 1 |
| Fukumitsu, K | 1 |
| Shimizuguchi, T | 1 |
| Hayakawa, S | 1 |
| Karasawa, K | 1 |
| Hang, J | 1 |
| Chen, J | 20 |
| Zhang, W | 15 |
| Yuan, T | 1 |
| Xu, Y | 4 |
| Zaouak, A | 2 |
| Benmously, R | 1 |
| Jannet, SB | 1 |
| Hammami, H | 1 |
| Fenniche, S | 1 |
| Kwon, HE | 1 |
| Ahn, HJ | 1 |
| Jeong, SJ | 1 |
| Shin, MK | 2 |
| Katarzyna, A | 1 |
| Agnieszka, G | 1 |
| Paweł, A | 1 |
| Magdalena, KD | 1 |
| Agnieszka, SW | 1 |
| Małgorzata, D | 1 |
| Agnieszka, L | 1 |
| Dominika, WD | 1 |
| Manuskiatti, W | 4 |
| Yan, C | 1 |
| Artzi, O | 3 |
| Gervasio, MKR | 1 |
| Wanitphakdeedecha, R | 2 |
| Neves, LMG | 1 |
| Wilgus, TA | 3 |
| Chobpenthai, T | 1 |
| Poosiripinyo, T | 1 |
| Tuntarattanapong, P | 1 |
| Thanindratarn, P | 1 |
| Trathitephun, W | 1 |
| Yu, L | 5 |
| Yang, YT | 2 |
| Zheng, W | 5 |
| Lin, G | 1 |
| Gong, C | 1 |
| Wei, H | 1 |
| Zhu, Z | 6 |
| Kong, W | 4 |
| Wang, H | 15 |
| Xiao, Y | 4 |
| Gan, L | 2 |
| Sun, Y | 10 |
| Tang, H | 3 |
| Xia, Z | 1 |
| Li, J | 13 |
| Zou, Y | 1 |
| Wang, S | 7 |
| Guo, S | 5 |
| Huang, Z | 3 |
| Huo, R | 7 |
| Xie, J | 6 |
| Chen, L | 9 |
| Cao, Y | 8 |
| Wu, D | 4 |
| Xiong, W | 1 |
| Zhang, K | 3 |
| Shi, J | 3 |
| Chen, Z | 4 |
| Chu, X | 2 |
| Xu, J | 11 |
| Amavi, AKA | 1 |
| Dossouvi, T | 1 |
| Adabra, K | 1 |
| Sakiye, KA | 1 |
| Tengue, K | 1 |
| Sun, J | 7 |
| Wo, Y | 1 |
| Wang, X | 48 |
| Zou, H | 1 |
| Li, B | 7 |
| Zhang, Y | 24 |
| Li, X | 27 |
| Jiang, R | 2 |
| Jin, H | 2 |
| Pan, L | 1 |
| Qin, H | 8 |
| Zhang, G | 13 |
| Yang, L | 2 |
| Zhang, L | 11 |
| Mohamed, R | 1 |
| Elawadi, AA | 1 |
| Al-Gendi, R | 1 |
| Al-Mohsen, S | 1 |
| Wani, S | 1 |
| Wafa, A | 1 |
| Li, T | 2 |
| Zhan, X | 1 |
| Mukherjee, A | 4 |
| Pandey, U | 1 |
| Shaikh, SH | 1 |
| Kumar, M | 2 |
| Kaushik, V | 1 |
| Jagasia, P | 1 |
| Kumar, SA | 1 |
| Dhami, PS | 1 |
| Wu, F | 1 |
| Chen, Y | 20 |
| Zhu, D | 1 |
| Jiang, T | 1 |
| Li, M | 6 |
| Qu, C | 3 |
| Tang, Z | 4 |
| Zhou, Z | 8 |
| Yu, Z | 3 |
| Xin, L | 1 |
| Shi, T | 1 |
| Choi, C | 1 |
| Mukovozov, I | 1 |
| Jazdarehee, A | 1 |
| Rai, R | 1 |
| Sachdeva, M | 1 |
| Shunmugam, M | 1 |
| Zaslavsky, K | 1 |
| Byun, S | 1 |
| Barankin, B | 2 |
| Cheong, KW | 1 |
| Yew, YW | 1 |
| Shim, J | 1 |
| Yeo, E | 1 |
| Park, JH | 11 |
| Bae, JH | 1 |
| Kim, SH | 4 |
| Lee, D | 1 |
| Lee, JH | 26 |
| Newman, R | 1 |
| Clebak, KT | 1 |
| Croad, J | 1 |
| Wile, K | 1 |
| Cathcart, E | 1 |
| Hwang, NH | 1 |
| Lee, NK | 1 |
| Chae, JH | 1 |
| Park, SH | 3 |
| Yoon, ES | 2 |
| Luk, K | 1 |
| Fakhoury, J | 1 |
| Ozog, D | 2 |
| Román-Sainz, J | 1 |
| Romero-Jiménez, B | 1 |
| Gruber-Velasco, F | 1 |
| Silvestre-Torner, N | 1 |
| Imbernón-Moya, A | 1 |
| Shan, M | 10 |
| Song, K | 11 |
| Chen, Q | 5 |
| Xia, Y | 12 |
| Wang, Y | 47 |
| Bacci, S | 2 |
| Tawaranurak, N | 1 |
| Pliensiri, P | 1 |
| Tawaranurak, K | 1 |
| Pires, JA | 1 |
| Bragato, EF | 1 |
| Momolli, M | 1 |
| Guerra, MB | 1 |
| Neves, LM | 1 |
| de Oliveira Bruscagnin, MA | 1 |
| Ratto Tempestini Horliana, AC | 1 |
| Porta Santos Fernandes, K | 1 |
| Kalil Bussadori, S | 1 |
| Agnelli Mesquita Ferrari, R | 1 |
| Teng, Y | 2 |
| Su, Y | 1 |
| Yin, B | 3 |
| Li, S | 7 |
| Cheng, X | 4 |
| He, Y | 7 |
| Jia, C | 3 |
| Jiao, H | 11 |
| Ji, G | 1 |
| Luo, B | 1 |
| Chen, C | 4 |
| Obi, EE | 1 |
| Kim, M | 2 |
| Mirsky, N | 1 |
| Spielman, A | 1 |
| Mathew, P | 1 |
| Yechieli, R | 1 |
| Tang, JC | 1 |
| Thaller, SR | 1 |
| Hung, YT | 1 |
| Lin, SM | 1 |
| Tzeng, IS | 1 |
| Ng, CY | 1 |
| Vanhooteghem, O | 2 |
| Erlendsson, AM | 1 |
| Rosenberg, LK | 1 |
| Lerche, CM | 1 |
| Togsverd-Bo, K | 1 |
| Wiegell, SR | 1 |
| Karmisholt, K | 1 |
| Philipsen, PA | 1 |
| Hansen, ACN | 1 |
| Janfelt, C | 1 |
| Holmes, J | 1 |
| Rossi, A | 3 |
| Haedersdal, M | 2 |
| Direder, M | 2 |
| Weiss, T | 2 |
| Copic, D | 2 |
| Vorstandlechner, V | 2 |
| Laggner, M | 2 |
| Pfisterer, K | 1 |
| Mildner, CS | 1 |
| Klas, K | 2 |
| Bormann, D | 2 |
| Haslik, W | 1 |
| Radtke, C | 1 |
| Farlik, M | 1 |
| Shaw, L | 1 |
| Golabi, B | 1 |
| Tschachler, E | 2 |
| Hoetzenecker, K | 1 |
| Ankersmit, HJ | 1 |
| Mildner, M | 2 |
| Liu, R | 4 |
| Xiao, H | 7 |
| Wang, R | 4 |
| Li, W | 12 |
| Deng, K | 3 |
| Cen, Y | 23 |
| Xu, X | 9 |
| Azarcon, CP | 1 |
| Wells, JR | 1 |
| Grossniklaus, HE | 2 |
| Li, Q | 19 |
| Tu, T | 4 |
| Bi, J | 2 |
| Yuan, C | 2 |
| Zhang, X | 19 |
| Yan, Y | 4 |
| Wang, B | 9 |
| Li, L | 7 |
| Fakhraei, S | 1 |
| Sazgarnia, A | 1 |
| Taheri, AR | 1 |
| Rajabi, O | 1 |
| Hoseininezhad, M | 1 |
| Zamiri, F | 1 |
| Ahmadpour, F | 1 |
| Park, JW | 1 |
| Shin, SH | 2 |
| Koh, YG | 2 |
| Seok, J | 1 |
| Choi, SY | 1 |
| Li, K | 2 |
| Kim, BJ | 3 |
| Yoo, KH | 1 |
| Mehta, H | 1 |
| Goyal, A | 3 |
| Narang, T | 2 |
| Chhabra, A | 2 |
| Pandey, S | 1 |
| Rathore, Y | 2 |
| Kaur, G | 1 |
| Lakhanpal, T | 1 |
| Singh Tanwar, K | 1 |
| Kumaran, MS | 1 |
| De, D | 3 |
| Shukla, J | 2 |
| De Decker, I | 1 |
| Hoeksema, H | 1 |
| Verbelen, J | 1 |
| Vanlerberghe, E | 1 |
| De Coninck, P | 1 |
| Speeckaert, MM | 1 |
| Blondeel, P | 1 |
| Monstrey, S | 6 |
| Claes, KEY | 1 |
| Sitaniya, S | 1 |
| Subramani, D | 1 |
| Jadhav, A | 1 |
| Sharma, YK | 1 |
| Deora, MS | 1 |
| Gupta, A | 1 |
| Akimoto, N | 1 |
| Väyrynen, JP | 1 |
| Zhao, M | 3 |
| Ugai, T | 1 |
| Fujiyoshi, K | 1 |
| Borowsky, J | 1 |
| Zhong, R | 1 |
| Haruki, K | 1 |
| Arima, K | 1 |
| Lau, MC | 1 |
| Kishikawa, J | 1 |
| Twombly, TS | 1 |
| Takashima, Y | 1 |
| Song, M | 9 |
| Wu, K | 1 |
| Chan, AT | 1 |
| Meyerhardt, JA | 1 |
| Giannakis, M | 1 |
| Nowak, JA | 1 |
| Ogino, S | 1 |
| Tosa, M | 10 |
| Ansai, SI | 4 |
| Bakry, OA | 3 |
| Samaka, RM | 4 |
| Fayez, N | 1 |
| Seleit, I | 3 |
| Liu, J | 21 |
| Yang, C | 3 |
| Zhang, H | 8 |
| Hu, W | 5 |
| Bergquist, J | 1 |
| Deng, T | 1 |
| Yang, X | 12 |
| Zhang, C | 5 |
| Zhu, Y | 6 |
| Chi, X | 1 |
| Mi, J | 1 |
| Yan, Q | 1 |
| Xu, Q | 3 |
| Yang, JX | 1 |
| Li, SY | 1 |
| Chen, ML | 1 |
| He, LR | 1 |
| Zhou, X | 6 |
| Lu, J | 3 |
| Wu, B | 3 |
| Guo, Z | 1 |
| Hengy, M | 1 |
| Veenstra, J | 1 |
| Perry, K | 1 |
| Ozog, DM | 5 |
| Friedman, BJ | 1 |
| Margiotta, E | 1 |
| Ramras, S | 1 |
| Shteynberg, A | 1 |
| Sun, H | 4 |
| Su, Z | 4 |
| Bazid, HAS | 1 |
| Mousa, MEA | 1 |
| Fan, J | 7 |
| Tian, J | 5 |
| Gan, C | 4 |
| Yang, Z | 8 |
| Huang, R | 3 |
| Martin, GC | 1 |
| Putterman, M | 1 |
| Dureau, P | 1 |
| Shinnawi, S | 1 |
| Gordin, A | 1 |
| Zaroura, I | 1 |
| Rafoul, B | 1 |
| Khoury, M | 1 |
| Cohen-Vaizer, M | 1 |
| Seoudy, WM | 1 |
| Mohy El Dien, SM | 1 |
| Abdel Reheem, TA | 1 |
| Elfangary, MM | 1 |
| Erfan, MA | 1 |
| Feng, G | 2 |
| Piao, M | 2 |
| Yuan, X | 6 |
| Chen, B | 15 |
| Wu, CH | 6 |
| Huang, YL | 1 |
| Hung, KS | 3 |
| Pai, TP | 1 |
| Liu, YT | 1 |
| Chen, TC | 1 |
| Chan, H | 1 |
| Hermenean, A | 1 |
| Oatis, D | 1 |
| Herman, H | 1 |
| Ciceu, A | 1 |
| D'Amico, G | 1 |
| Trotta, MC | 1 |
| Lewandowski, M | 1 |
| Świerczewska, Z | 1 |
| Barańska-Rybak, W | 1 |
| Oettgen, F | 2 |
| Haubner, F | 3 |
| Yu, Q | 6 |
| Song, L | 2 |
| Tang, M | 2 |
| Gu, Q | 1 |
| Li, P | 5 |
| Zhou, N | 1 |
| Cho, MY | 2 |
| Song, A | 1 |
| Chung, KY | 3 |
| Roh, MR | 5 |
| Feng, QL | 4 |
| Gu, JJ | 3 |
| Chen, JY | 2 |
| Zheng, WY | 1 |
| Pan, HH | 2 |
| Xu, XY | 2 |
| Deng, CC | 7 |
| Yang, B | 11 |
| Huang, RL | 3 |
| Liu, C | 7 |
| Fu, R | 2 |
| Yang, J | 6 |
| Ito, H | 1 |
| Nakamura, Y | 4 |
| Takanari, K | 1 |
| Oishi, M | 1 |
| Matsuo, K | 1 |
| Kanbe, M | 1 |
| Uchibori, T | 1 |
| Ebisawa, K | 1 |
| Kamei, Y | 1 |
| Limmer, EE | 3 |
| Kerby, E | 2 |
| Lies, S | 1 |
| Limmer, B | 1 |
| Limmer, R | 1 |
| Teske, N | 1 |
| Savory, S | 1 |
| Reisch, JS | 1 |
| Glass, DA | 11 |
| Gao, H | 2 |
| Hu, Z | 12 |
| Huang, J | 14 |
| Zhou, G | 5 |
| Wang, P | 10 |
| Qi, S | 2 |
| Tang, J | 2 |
| Ud-Din, S | 7 |
| Wang, HC | 2 |
| Zhang, Z | 17 |
| Long, X | 20 |
| Xing, B | 1 |
| Lubov, JE | 1 |
| Rohan, CA | 1 |
| Travers, JB | 1 |
| Hill, MJ | 1 |
| Aranda, A | 1 |
| Lin, P | 3 |
| Peng, R | 2 |
| Li, H | 12 |
| Artz, M | 1 |
| Trimaille, A | 1 |
| Labouche, A | 1 |
| Kerfant, N | 5 |
| Misery, L | 1 |
| Wen, X | 2 |
| Du, H | 2 |
| Hao, X | 1 |
| Guo, Y | 4 |
| Huang, C | 10 |
| Ni, Z | 1 |
| Song, J | 4 |
| Zhu, F | 5 |
| Lee, SY | 5 |
| Lee, AR | 2 |
| Choi, JW | 4 |
| Lee, CR | 1 |
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| Rubinstein, JH | 1 |
| Miller, RW | 1 |
| Sällström, KO | 1 |
| Larson, O | 1 |
| Hedén, P | 1 |
| Eriksson, G | 1 |
| Glas, JE | 1 |
| Ringborg, U | 1 |
| Ow, RK | 1 |
| Goihman-Yahr, M | 1 |
| Cabello de Brito, I | 1 |
| Bastardo de Albornoz, MC | 1 |
| de Gomez, MH | 1 |
| Pereira, J | 1 |
| de Román, A | 1 |
| San Martín, B | 1 |
| Molina, T | 1 |
| Wagner, HN | 1 |
| Holubec, H | 1 |
| Ulreich, JB | 1 |
| Scuderi, P | 1 |
| McNutt, NS | 1 |
| Hsu, A | 1 |
| Rockwell, WB | 1 |
| Kovalic, JJ | 1 |
| Schopohl, B | 1 |
| Schnepper, E | 1 |
| Myers, JC | 1 |
| Sagher, U | 1 |
| Stern, JC | 1 |
| Harper, RA | 1 |
| Sheridan, D | 1 |
| Shirakami, A | 1 |
| Shigekiyo, T | 1 |
| Hirai, Y | 1 |
| Takeichi, T | 1 |
| Kawauchi, S | 1 |
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| Miyoshi, K | 1 |
| Wester, JU | 1 |
| Pilegaard, J | 1 |
| Hahn, T | 1 |
| Mercer, NS | 1 |
| Halber, S | 1 |
| Salfeld, K | 1 |
| Brauner, GJ | 1 |
| Schliftman, A | 1 |
| Zachariae, H | 1 |
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| Oikarinen, AI | 2 |
| Prockop, DJ | 1 |
| Rubenstein, R | 1 |
| Roenigk, HH | 1 |
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| Dunn, JF | 1 |
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| Pech, A | 1 |
| Cannoni, M | 1 |
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| Rodríguez-Eaton, S | 1 |
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| Patil, RB | 1 |
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| Daly, TJ | 1 |
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| Lawson, W | 1 |
| Schwartz, IS | 1 |
| Manikhas, MG | 1 |
| Egorova, MA | 1 |
| Orlova, EV | 1 |
| Litoux, P | 1 |
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| Blankstein, A | 1 |
| Russo, PM | 1 |
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Clinical Trials (70)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of the Combination of Photobiomodulation Therapy and the Intralesional Administration of Corticoid in the Preoperative and Postoperative Periods of Keloid Surgery: a Randomized, Controlled, Double-blind Trial[NCT04824612] | 58 participants (Anticipated) | Interventional | 2021-08-30 | Enrolling by invitation | |||
| The Effectiveness of Dry Needling in Treating Linear Hypertrophic Scar Tissue: a Randomized Sham-controlled Trial[NCT06033430] | 80 participants (Anticipated) | Interventional | 2023-10-10 | Recruiting | |||
| Self-controlled, Single-site Trial Investigation of Laser Assisted Drug Delivery of NanoDOX®[NCT05411484] | Phase 2 | 12 participants (Anticipated) | Interventional | 2023-10-23 | Recruiting | ||
| Randomized Controlled Clinical Study (RCT) Phase 3 of the Safety and Efficacy of Hypochlorous Acid in the Prophylaxis of Healthcare Personnel at High Risk of Infection by SARS-CoV2 (COVID19) Versus Placebo[NCT04684550] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2021-02-15 | Withdrawn (stopped due to The study did not achieve funding or approval by the ethics committee. Once the vaccination phase was entered, the study lost validity and was not viable) | ||
| A Prospective, Longitudinal, Intraindividual Clinical Study in Keloid With Multimodal Ultrasound Assessment[NCT06034587] | 34 participants (Actual) | Observational | 2021-07-21 | Completed | |||
| Open Label Prospective Trial of Fractional Ablative CO 2 Resurfacing With Laser- Facilitated Steroid Delivery in Patients With Mild to Moderate Hidradenitis Suppurativa.[NCT05580029] | Early Phase 1 | 10 participants (Anticipated) | Interventional | 2022-11-01 | Not yet recruiting | ||
| Metabolic Profiling of Immune Responses in Immune-Mediated Diseases[NCT04864886] | 200 participants (Anticipated) | Observational | 2021-08-10 | Recruiting | |||
| The Effect of Ethosomal Gel Bearing Losartan 5% on The Patient and Observer Scar Assessment Scale Score, Degree of Erythema and Pigmentation, Surface Area, Thickness and Pliability of Human Keloids[NCT05893108] | Phase 1/Phase 2 | 46 participants (Anticipated) | Interventional | 2024-03-30 | Not yet recruiting | ||
| Silicone Taping for the Improvement of Abdominal Donor Site Scars Following Autologous Breast Reconstruction; A Randomized, Prospective Controlled Trial[NCT04506255] | 32 participants (Anticipated) | Interventional | 2020-11-16 | Recruiting | |||
| Identification of Genetic Variants That Contribute to Keloid Formation in Families and Isolated Cases.[NCT01619553] | 7,000 participants (Anticipated) | Observational | 2009-04-30 | Recruiting | |||
| The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation: A Prospective, Controlled, Randomized, Double-blinded Study[NCT03887377] | Phase 2/Phase 3 | 22 participants (Anticipated) | Interventional | 2019-06-10 | Enrolling by invitation | ||
| Efficacy of Autologous Adipose Derived Stromal Vascular Fraction in the Treatment of Keloids[NCT04391621] | Phase 2 | 30 participants (Anticipated) | Interventional | 2021-05-01 | Recruiting | ||
| Autologous Adipose Derived Stem Cell Transplantation in the Treatment of Keloids. A Pilot Randomized Controlled Trial[NCT04553159] | Phase 2 | 8 participants (Actual) | Interventional | 2021-03-01 | Completed | ||
| Efficay of Autologous Platelet Rich Plasma Obtained With RgenKit-BCT in the Prevention and the Treatment of Keloid Scars[NCT02922972] | 15 participants (Actual) | Interventional | 2014-09-30 | Completed | |||
| Efficacy of Post-Surgical Intralesional Injection With Triamcinolone Versus Triamcinolone Plus Fluorouracil in the Treatment of Keloids[NCT04710719] | 7 participants (Actual) | Interventional | 2021-02-01 | Completed | |||
| Regenerative Effects of Human Stem Cell Media After Laser Therapy in Hypertrophic Scar Caused by Burns[NCT05004779] | 30 participants (Anticipated) | Interventional | 2021-08-10 | Not yet recruiting | |||
| Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization[NCT05478551] | Phase 2/Phase 3 | 12 participants (Anticipated) | Interventional | 2022-06-01 | Active, not recruiting | ||
| Examining the Therapeutic Potential of Botulinum Toxin Type A in the Treatment of Keloids[NCT05330078] | Early Phase 1 | 10 participants (Actual) | Interventional | 2022-03-11 | Active, not recruiting | ||
| Open, Non-comparative, Multicentre Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Janesse® (Hyaluronic Acid-dermal Filler) in the Treatment of Facial Dermal Tissue Defects[NCT05239156] | 48 participants (Actual) | Interventional | 2022-03-14 | Completed | |||
| Open, Non-comparative, Multicentre Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Plenhyage® (Polymerised Polynucleotides Dermal Filler) in the Treatment of Dermal Tissue Defects[NCT05239117] | 48 participants (Actual) | Interventional | 2022-03-30 | Active, not recruiting | |||
| Open, Non-comparative, Multicentre Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Auralya® (Hyaluronic Acid-dermal Filler) in the Treatment of Facial Dermal Tissue Defects[NCT05239130] | 48 participants (Actual) | Interventional | 2022-03-21 | Active, not recruiting | |||
| Open, Non-comparative, Multicentre Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Jalucomplex® (Hyaluronic Acid-dermal Filler) in the Treatment of Facial and Neck Dermal Tissue Defects[NCT05239351] | 48 participants (Actual) | Interventional | 2022-03-07 | Completed | |||
| Vicryl Rapide Versus Nonabsorbable Suture in Repair of Simple Traumatic Extremity and Trunk Lacerations in Adult Patients[NCT04056013] | 96 participants (Anticipated) | Interventional | 2019-09-26 | Recruiting | |||
| The Role of 5-Fluorouracil in Post-Operative Scar Formation Following Direct Brow Ptosis Repair[NCT03219580] | Phase 3 | 50 participants (Anticipated) | Interventional | 2017-05-20 | Enrolling by invitation | ||
| Randomized Comparative Open Trial of Occlusive Therapy With a Hydrocolloid or Silicone Versus Conventional Drying Treatment for the Local Care of Acute Lesions Caused by Herpes Zoster.[NCT04258930] | 36 participants (Anticipated) | Interventional | 2020-02-26 | Recruiting | |||
| The Application of Preoperative Silicone Ointment and Its Effect on Wound Healing[NCT05461157] | 60 participants (Anticipated) | Interventional | 2022-11-14 | Enrolling by invitation | |||
| Effectiveness and Tolerability of an Overnight 4-week Treatment With Patch Containing Onion Extract and Allantoin for Cesarean Section Scars[NCT04046783] | 93 participants (Actual) | Observational | 2019-03-02 | Completed | |||
| Analysis of Soluble Mediators of Inflammation and Angiogenesis in the Vitreous of Patients With Diabetic Retinopathy Treated With Curcumin/Homotaurine/Vit. D3[NCT04378972] | 25 participants (Actual) | Observational | 2019-09-16 | Completed | |||
| Effect of Cryotherpy on Hypertrophic Scar[NCT04532840] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2019-04-15 | Active, not recruiting | ||
| Evaluating the Efficacy of an Ablative Fractional Carbon Dioxide Laser on Pathologic Symptoms in Pediatric Hypertrophic Scars: a Prospective Split-scar Controlled Trial[NCT04236167] | 6 participants (Actual) | Interventional | 2020-11-01 | Terminated (stopped due to Lack of participants to enroll. Early findings not supportive of fractionated c02 laser improving scars in population studied when used alone.) | |||
| Influence of Surgical Scar Resection, Followed by Reconstruction With Integra and Split Skin Grafts on Quality of Life, Body Perception, Scar Perception and Stigmatization in Patients With Non-Suicidal Self-Inflicted Scars[NCT04420442] | 15 participants (Anticipated) | Interventional | 2018-11-06 | Recruiting | |||
| Prospective Evaluation of the Use of High-dose-rate Brachytherapy for the Treatment of Recalcitrant Keloids[NCT02005055] | 43 participants (Actual) | Observational | 2003-01-31 | Completed | |||
| Intralesional Cryotherapy With a Argon Gas Based Device for the Treatment of Keloid and Hypertrophic Scars[NCT02063243] | 33 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| Phase I Study of High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin[NCT02630303] | Phase 1 | 60 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| EBIRE: Phase 1 Study of High Fluence LED-Red Light in Fitzpatrick Skin Types I to III[NCT03433222] | Phase 1 | 60 participants (Anticipated) | Interventional | 2018-01-31 | Recruiting | ||
| Intralesional Cryotherapy for Treatment of Keloid Scars: a Prospective Evaluation[NCT01994616] | 30 participants (Actual) | Observational | 2009-01-31 | Completed | |||
| A Randomized, Placebo-Controlled, Double-Blind, Prospective Clinical Trial of Botulinum Toxin Type A in Prevention of Hypertrophic Scar Development in Median Sternotomy Wound[NCT02886988] | Phase 2/Phase 3 | 17 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| Botulinum Toxin to Improve Results in Epicanthoplasty[NCT03294382] | Phase 3 | 42 participants (Anticipated) | Interventional | 2017-04-01 | Recruiting | ||
| Intra-lesional ACE Inhibitor for Treatment of Hypertrophic Scars[NCT05259137] | Phase 2/Phase 3 | 30 participants (Anticipated) | Interventional | 2023-08-31 | Not yet recruiting | ||
| Combined Treatment With Nonablative Fractional Laser and Radiofrequency Microneedling for the Treatment of Acne Scars: A Prospective, Randomized, Split-Face Study[NCT05105334] | 20 participants (Anticipated) | Interventional | 2021-11-08 | Not yet recruiting | |||
| Investigation of the Effectiveness of Vibratory Stimulus in Trigger Finger Injections[NCT05405452] | Phase 4 | 1,000 participants (Anticipated) | Interventional | 2023-08-14 | Recruiting | ||
| Vibration Anesthesia for Pain Reduction During Trigger Point Injection to the Gastrocnemius[NCT03365674] | 60 participants (Actual) | Interventional | 2017-09-30 | Completed | |||
| Intralesional Cryosurgery for the Treatment of Basal Cell Carcinoma of the Lower Extremities in the Elderly - a Feasibility Study[NCT01633515] | 10 participants (Anticipated) | Interventional | 2012-07-31 | Recruiting | |||
| Topical Treatment With Glucocorticoids to Prevent Hypertrophic Scars and Keloid Due to Central Venous Access in Children[NCT01113125] | Phase 3 | 60 participants (Anticipated) | Interventional | 2010-03-31 | Active, not recruiting | ||
| Comparison of Safety and Efficacy of Tazarotene 0.1% Plus Clindamycin 1% Gel vs. Adapalene 0.1% Plus Clindamycin 1% Gel in the Treatment of Facial Acne Vulgaris: A Randomized Controlled Trial[NCT02721173] | Phase 4 | 60 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| Autologous Fat Cells Transfer for the Treatment of Atrophic Post Acne Scars: Clinical Trail[NCT05028283] | 69 participants (Actual) | Interventional | 2021-08-19 | Completed | |||
| A Phase 1B Dose Escalating Study of the Safety, Short-Term Engraftment and Action of a Singly-Applied NB01 in Adults With Moderate Acne[NCT03450369] | Phase 1 | 10 participants (Actual) | Interventional | 2018-01-24 | Completed | ||
| Serum apelin12 in Acne Vulgaris[NCT03480503] | 90 participants (Anticipated) | Observational | 2018-05-31 | Not yet recruiting | |||
| Assessing and Improving Patient Knowledge About Keloids[NCT01176877] | 40 participants (Actual) | Interventional | 2010-08-31 | Completed | |||
| Chemotherapy (CT) Followed by Donor Lymphocyte Infusion (DLI) Plus Interleukin 2 (IL-2) for Patients With Relapse Acute Myeloid or Lymphoid Leukemia After Allogeneic Hematopoietic Transplant[NCT00005802] | Phase 1/Phase 2 | 0 participants | Interventional | 1999-06-30 | Completed | ||
| Post-Marketing Study of Radiesse® Injectable Dermal Filler for the Treatment of Nasolabial Folds in Persons of Color[NCT01012388] | Phase 4 | 100 participants (Actual) | Interventional | 2007-03-31 | Completed | ||
| Non-Ablative Fractional Resurfacing of Total Knee Replacement Scars[NCT02166138] | 108 participants (Anticipated) | Interventional | 2013-11-30 | Recruiting | |||
| EGF-loaded Chitosan to Facilitate Epithelial Healing And Prevent Scar Formation of Cesarean Wound[NCT04211597] | 60 participants (Actual) | Interventional | 2017-09-05 | Completed | |||
| Pilot Study of Prospective Clinical Trials on Skin Wound Healing in Young and Aged Individuals[NCT01040104] | 51 participants (Actual) | Observational | 2009-07-31 | Completed | |||
| A Prospective Randomized Study Assessing Post Operative Wound Infections Along With Cosmetic Outcomes Using Silver Impregnated Dressings Compared to Conventional Dressings on Cesarean Section Incisions[NCT01697748] | 660 participants (Actual) | Interventional | 2013-09-30 | Completed | |||
| Effect of Pulse Width of a 595-nm Flashlamp-pumped Pulsed-dye Laser on the Treatment Response of Keloidal and Hypertrophic Sternotomy Scars[NCT00142441] | 19 participants | Interventional | 2003-06-30 | Completed | |||
| Evaluation of a Filming Formulation of Hydrogen Peroxide and Hyaluronic Acid (BMG0703) in Promoting the Healing of Post-extraction Sites, Compared to Placebo and 0.2% Chlorhexidine. A Randomised Controlled Clinical Trial.[NCT04438434] | Phase 3 | 57 participants (Anticipated) | Interventional | 2020-06-30 | Not yet recruiting | ||
| Comparison of the Effectiveness in Prevention of Hypertrophic Scars or Keloids Between Silicone Sheet, Silicone Gel and Paper Steri-strip-A Randomised Controlled Trial.[NCT00849004] | 75 participants (Anticipated) | Interventional | 2009-03-31 | Active, not recruiting | |||
| Pilot Study to Evaluate Clinical Outcomes With the Use of Biovance, a Dehydrated Decellularized Human Amnion Membrane Allograft, Following Keloid Revision Surgery[NCT02521402] | Phase 4 | 10 participants (Anticipated) | Interventional | 2015-08-31 | Not yet recruiting | ||
| A Prospective Intra-patient Single-blinded Randomised Trial to Examine the Mechanistic Basis of fractiOnal Ablative carbOn Dioxide Laser Therapy in Treating Adult Burns and/or Trauma Patients With Hypertrophic Scarring[NCT04736251] | 60 participants (Anticipated) | Observational | 2019-12-09 | Recruiting | |||
| The Effect of Different Intervals of 595-nm Pulsed Dye Laser Sessions on Improvement of Surgical Scars: A Double Blind Randomised Clinical Trial[NCT00506090] | 0 participants (Actual) | Interventional | 2007-07-31 | Withdrawn (stopped due to Because of unsatisfactory results of previous trial which assessed the effect of different onset times of PDL on surgical scars.) | |||
| The Effect of Different Onset Times of Treatment With 595-nm Pulsed Dye Laser on Improvement of Surgical Scars: A Double Blind Randomised Clinical Trial[NCT00506363] | 15 participants (Anticipated) | Interventional | 2008-01-31 | Terminated (stopped due to The trial was terminated on May 2008 after inclusion of 10 patients due to low recruitment and patient compliance.) | |||
| Bacillus Calmette-Guerin Against Covid-19 for Prevention and Amelioration of Severity Trial[NCT04534803] | Phase 3 | 0 participants (Actual) | Interventional | 2021-09-30 | Withdrawn (stopped due to At this time it has been decided by the study team the the study will no longer take place in the United States.) | ||
| Non-cultured Autologous Keratinocyte Suspension for Treatment of Deep Dermal Burn and Post-Burn Raw Area Versus Traditional Split Skin Graft[NCT03675568] | 0 participants (Actual) | Interventional | 2018-11-01 | Withdrawn (stopped due to Subject changed) | |||
| Non-cultured Autologous Keratinocyte Suspension Versus Adipose-Derived Stem Cell-Keratinocyte Suspension for Coverage of Post-Burn Raw Area: A Comparative Clinical Study[NCT03686449] | 33 participants (Anticipated) | Interventional | 2020-11-01 | Not yet recruiting | |||
| Fractional Ablative CO2 Laser Treatment for Acne Scars in Patients Receiving Oral Isotretinoin[NCT04870489] | Phase 2 | 30 participants (Anticipated) | Interventional | 2017-11-01 | Active, not recruiting | ||
| A Prospective, Randomized, Investigator-blinded, Placebo-controlled, Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars[NCT00754247] | Phase 4 | 30 participants (Actual) | Interventional | 2006-03-31 | Completed | ||
| 6 Month Double-Blind Randomized Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Small Particle Hyaluronic Acid to Treat Acne Scars Located on the Cheeks and Forehead[NCT02955381] | 26 participants (Actual) | Interventional | 2017-03-28 | Terminated (stopped due to Liquidation of Research Department) | |||
| Role of Bronchoscopy in Assessment of Patients With Post-intubation Tracheal Stenosis[NCT04625400] | 87 participants (Anticipated) | Interventional | 2021-01-01 | Not yet recruiting | |||
| Radiotherapy to Prevent Fibrosis After Lumbar Laminectomy[NCT00018876] | Phase 1 | 46 participants | Interventional | 2000-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Number of Participants With Successful Engraftment of Probiotic Following a Single Application.
Engraftment is defined as the percentage of bacteria recovered from hair follicles that are health-associated (NB01) as measured with proprietary quantitative polymerase chain assays. Successful follicular engraftment, defined as both deoR/PanBac >40% and Cas5/PanBac >40% in the Day 2 (24H) ) Biore Strip samples. Cas5/PanBac and deoR/PanBac are the percentages of bacteria in a sample containing the CRISPR associated protein Cas5 and a repressor of porphyrin production deoR, respectively. Pan-Bacterial (PanBac) is a loci found in nearly all bacteria found on the face and thus serves as the denominator to calculate the percentage of bacteria with any loci. (NCT03450369)
Timeframe: 2 Months
| Intervention | Participants (Count of Participants) |
|---|---|
| Low Dose | 2 |
| High Dose | 1 |
Dose Schedule Determination Based on Time to Peak deoR and Cas5
To determine longevity of the live biotherapeutic after a single application, swab samples were collected at Baseline, 6, 24 and 48 hours after application, and genotyped as above. For each participant the absolute change, from Baseline, in the percentage of the two loci present in the live biotherapeutic (deoR and Cas5) were calculated. A significant positive change is indicative of the continued presence of the live biotherapeutic. (NCT03450369)
Timeframe: From Baseline to 48 hours after application
| Intervention | % of total bacteria w/ genotype (Mean) | |||||
|---|---|---|---|---|---|---|
| Genotype 1 (deoR), 6 hours | Genotype 1 (deoR), 24 hours | Genotype 1 (deoR), 48 hours | Genotype 2 (Cas 5), 6 hours | Genotype 2 (Cas 5), 24 hours | Genotype 2 (Cas 5), 48 hours | |
| High Dose | 51.2 | 5.2 | 2.8 | 48.4 | 4.4 | 1.8 |
| Low Dose | -0.4 | -4.2 | 13.8 | 12.8 | 3.4 | 3.2 |
Number of Participants With Change in Investigator Assessment of Tolerability Score: Conjunctival Injection
Safety profile and tolerability of a singly applied NB01 using the Investigator Assessment of Tolerability Scoring (0 = None; 1 = Slight; 2 = Moderate; 3 = Intense) for Conjunctival Injection. Reference: ClinicalTrials.gov: Investigator Assessment Tolerability Scoring: A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Acne. (NCT03450369)
Timeframe: From Screening to 28 days after application, typically 2 months
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Screening, scale = 0 (none) | Day 1 (0 hours), scale = 0 (none) | Day 1 (6 hours), scale = 0 (none) | Day 2, scale = 0 (none) | Day 3, scale = 0 (none) | Day 7, scale = 0 (none) | Day 28, scale = 0 (none) | |
| High Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
| Low Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
Number of Participants With Change in Investigator Assessment of Tolerability Score: Hyperpigmentation
Safety profile and tolerability of a singly applied NB01 using the Investigator Assessment of Tolerability Scoring (0 = None; 1 = Slight; 2 = Moderate; 3 = Intense) for Hyperpigmentation. Reference: ClinicalTrials.gov: Investigator Assessment Tolerability Scoring: A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Acne. (NCT03450369)
Timeframe: From Screening to 28 days after application, typically 2 months
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Screening, scale = 0 (none) | Day 1 (0 hours), scale = 0 (none) | Day 1 (6 hours), scale = 0 (none) | Day 2, scale = 0 (none) | Day 3, scale = 0 (none) | Day 7, scale = 0 (none) | Day 28, scale = 0 (none) | |
| High Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
| Low Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
Number of Participants With Change in Investigator Assessment of Tolerability Score: Irritant/Allergic Contact Dermatitis
Safety profile and tolerability of a singly applied NB01 using the Investigator Assessment of Tolerability Scoring (0 = None; 1 = Slight; 2 = Moderate; 3 = Intense) for Irritant/Allergic Contact Dermatitis. Reference: ClinicalTrials.gov: Investigator Assessment Tolerability Scoring: A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Acne. (NCT03450369)
Timeframe: From Screening to 28 days after application, typically 2 months
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Screening, scale = 0 (none) | Day 1 (0 hours), scale = 0 (none) | Day 1 (6 hours), scale = 0 (none) | Day 2, scale = 0 (none) | Day 3, scale = 0 (none) | Day 7, scale = 0 (none) | Day 28, scale = 0 (none) | |
| High Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
| Low Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
Number of Participants With Change in Investigator Assessment of Tolerability Score: Mucosal Toxicity
Safety profile and tolerability of a singly applied NB01 using the Investigator Assessment of Tolerability Scoring (0 = None; 1 = Slight; 2 = Moderate; 3 = Intense) for Mucosal Toxicity. Reference: ClinicalTrials.gov: Investigator Assessment Tolerability Scoring: A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Acne. (NCT03450369)
Timeframe: From Screening to 28 days after application, typically 2 months
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Screening, scale = 0 (none) | Day 1 (0 hours), scale = 0 (none) | Day 1 (6 hours), scale = 0 (none) | Day 2, scale = 0 (none) | Day 3, scale = 0 (none) | Day 7, scale = 0 (none) | Day 28, scale = 0 (none) | |
| High Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
| Low Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
Number of Participants With Change in Investigator Assessment of Tolerability Score: Ocular Irritation
Safety profile and tolerability of a singly applied NB01 using the Investigator Assessment of Tolerability Scoring (0 = None; 1 = Slight; 2 = Moderate; 3 = Intense) for Ocular Irritation. Reference: ClinicalTrials.gov: Investigator Assessment Tolerability Scoring: A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Acne. (NCT03450369)
Timeframe: From Screening to 28 days after application, typically 2 months
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Screening, scale = 0 (none) | Day 1 (0 hours), scale = 0 (none) | Day 1 (6 hours), scale = 0 (none) | Day 2, scale = 0 (none) | Day 3, scale = 0 (none) | Day 7, scale = 0 (none) | Day 28, scale = 0 (none) | |
| High Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
| Low Dose | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
Number of Participants With Change in Investigator Assessment of Tolerability Score: Skin Dryness.
Safety profile and tolerability of a singly applied NB01 using the Investigator Assessment of Tolerability Scoring (0 = None; 1 = Slight; 2 = Moderate; 3 = Intense) for Skin Dryness. Reference: ClinicalTrials.gov: Investigator Assessment Tolerability Scoring: A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Acne. (NCT03450369)
Timeframe: From Screening to 28 days after application, typically 2 months
| Intervention | Participants (Count of Participants) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Screening, scale = 0 (none) | Screening, scale = 1 (slight) | Day 1 (0 hours), scale = 0 (none) | Day 1 (0 hours), scale = 1 (slight) | Day 1 (6 hours), scale = 0 (none) | Day 1 (6 hours), scale = 1 (slight) | Day 2, scale = 0 (none) | Day 2, scale = 1 (slight) | Day 3, scale = 0 (none) | Day 3, scale = 1 (slight) | Day 7, scale = 0 (none) | Day 28, scale = 0 (none) | Day 28, scale = 1 (slight) | |
| High Dose | 5 | 0 | 5 | 0 | 5 | 0 | 5 | 0 | 5 | 0 | 5 | 5 | 0 |
| Low Dose | 4 | 1 | 4 | 1 | 4 | 1 | 4 | 1 | 4 | 1 | 5 | 3 | 2 |
Number of Participants With Change in Investigator Assessment of Tolerability Score: Skin Erythema.
Safety profile and tolerability of a singly applied NB01 using the Investigator Assessment of Tolerability Scoring (0 = None; 1 = Slight; 2 = Moderate; 3 = Intense) for Skin Erythema. Reference: ClinicalTrials.gov: Investigator Assessment Tolerability Scoring: A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Acne. (NCT03450369)
Timeframe: From Screening to 28 days after application, typically 2 months
| Intervention | Participants (Count of Participants) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Screening, scale = 0 (none) | Screening, scale = 1 (slight) | Day 1 (0 hours), scale = 0 (none) | Day 1 (0 hours), scale = 1 (slight) | Day 1 (0 hours), scale = 2 (moderate) | Day 1 (6 hours), scale = 0 (none) | Day 1 (6 hours), scale = 1 (slight) | Day 1 (6 hours), scale = 2 (moderate) | Day 2, scale = 0 (none) | Day 2, scale = 1 (slight) | Day 3, scale = 0 (none) | Day 3, scale = 1 (slight) | Day 7, scale = 0 (none) | Day 7, scale = 1 (slight) | Day 28, scale = 0 (none) | |
| High Dose | 5 | 0 | 5 | 0 | 0 | 5 | 0 | 0 | 5 | 0 | 5 | 0 | 5 | 0 | 5 |
| Low Dose | 2 | 3 | 3 | 1 | 1 | 3 | 1 | 1 | 4 | 1 | 4 | 1 | 4 | 1 | 5 |
Number of Participants With Change in Investigator Assessment of Tolerability Score: Skin Peeling
Safety profile and tolerability of a singly applied NB01 using the Investigator Assessment of Tolerability Scoring (0 = None; 1 = Slight; 2 = Moderate; 3 = Intense) for Skin Peeling. Reference: ClinicalTrials.gov: Investigator Assessment Tolerability Scoring: A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Acne. (NCT03450369)
Timeframe: From Screening to 28 days after application, typically 2 months
| Intervention | Participants (Count of Participants) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Screening, scale = 0 (none) | Screening, scale = 1 (slight) | Day 1 (0 hours), scale = 0 (none) | Day 1 (0 hours), scale = 1 (slight) | Day 1 (6 hours), scale = 0 (none) | Day 1 (6 hours), scale = 1 (slight) | Day 2, scale = 0 (none) | Day 3, scale = 0 (none) | Day 7, scale = 0 (none) | Day 28, scale = 0 (none) | |
| High Dose | 5 | 0 | 5 | 0 | 5 | 0 | 5 | 5 | 5 | 5 |
| Low Dose | 3 | 2 | 4 | 1 | 4 | 1 | 5 | 5 | 5 | 5 |
Number of Participants With Change in Investigator Global Assessment (IGA) Score
"Number of participants with a changed Investigator Global Assessment (IGA) score after single application of NB01; positive number if grade is reduced (e.g. from 3 to 2) or negative number is IGA grade increased.~The Investigator Global Assessment 5-Point Score is a standard FDA acne assessment tool with scoring as follows:~Grade 0-Clear (Clear skin with no inflammatory or non-inflammatory lesions. The category of clear should represent true absence of disease) Grade1-Almost Clear (A few scattered comedones and no more than one small papule) Grade 2-Mild (Some comedones, some papules and pustules; no nodules) Grade 3-Moderate (Many comedones, papules and pustules; one nodule may be present) Grade 4-Severe (Covered with comedones, numerous papules and pustules and no more than a few nodular lesions)" (NCT03450369)
Timeframe: 28 Days
| Intervention | Participants (Count of Participants) | ||||
|---|---|---|---|---|---|
| Participants with changed IGA @ 6 hours | Participants with changed IGA @ 1 day | Participants with changed IGA @ 2 days | Participants with changed IGA @ 6 days | Participants with changed IGA @ 28 days | |
| High Dose | 0 | 0 | 0 | 0 | 0 |
| Low Dose | 0 | 0 | 0 | 0 | 2 |
Safety Profile and Tolerability of a Singly Applied NB01 Using Acne Lesion Counts.
Absolute Lesion Count: All Lesions for the Whole Face; with higher numbers of lesion representing worsening or more severe acne (NCT03450369)
Timeframe: From Screening to 28 days after application, typically 2 months
| Intervention | count of lesions (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Screening | Day 1 (0 hours) | Day 1 (6 hours) | Day 2 | Day 3 | Day 7 | Day 28 | |
| High Dose | 38.8 | 42.6 | 39.8 | 38.2 | 35.4 | 34.2 | 32.6 |
| Low Dose | 49.4 | 22.6 | 21.0 | 31.6 | 32.2 | 25.6 | 25.8 |
To Assess the Impact of an Educational Lecture on Knowledge About Keloid Scars by Comparing Mean Scores Between Knowledge Assessment Questionnaires Administered Before an Educational Lecture and Immediately After an Educational Lecture
All subjects completed a written questionnaire to assess knowledge about keloid scars before an educational lecture about keloids, immediately after the educational lecture about keloids, and 3 months after the educational lecture about keloids. This written questionnaire to assess knowledge about keloid scars contained 19 questions related to risk factors for developing keloid scars, keloid scar prevention, and keloid scar treatment. A correct response to a question was awarded 1 point and all correct responses were summed to achieve a total score. Possible total score ranged from 0 to 19. A score of 0 is associated with worse knowledge about keloid scars and a score of 19 is associated with better knowledge about keloid scars. (NCT01176877)
Timeframe: immediately before and after a 5 minute educational lecture
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Pre-educational lecture score | Immediate post-educational lecture score | |
| Keloid Scar | 12.9 | 18.3 |
To Assess the Impact of an Educational Lecture on Long-term Knowledge Retention About Keloid Scars by Comparing Mean Scores Between Knowledge Assessment Questionnaires Administered Before an Educational Lecture and 3 Months After an Educational Lecture
All subjects completed a written questionnaire to assess knowledge about keloid scars before an educational lecture about keloids, immediately after the educational lecture about keloids, and 3 months after the educational lecture about keloids. This written questionnaire to assess knowledge about keloid scars contained 19 questions related to risk factors for developing keloid scars, keloid scar prevention, and keloid scar treatment. A correct response to a question was awarded 1 point and all correct responses were summed to achieve a total score. Possible total score ranged from 0 to 19. A score of 0 is associated with worse knowledge about keloid scars and a score of 19 is associated with better knowledge about keloid scars. (NCT01176877)
Timeframe: before and 3 months after a 5 minute educational lecture
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Pre-educational lecture score | 3 months post-educational lecture score | |
| Keloid Scars | 13.2 | 16.8 |
Number Participants With Hypertropic Scarring, Keloid Formation, Hyper- or Hypopigmentation in Patients With Fitzpatrick Skin Types IV, V, and VI Receiving Nasolabial Fold Treatment
Skin type IV - Burns minimally, tans moderately and easily, Skin type V - Rarely burns, tans profusely; Skin type VI - Never burns, tans profusely (NCT01012388)
Timeframe: 3 months
| Intervention | Participants (Number) |
|---|---|
| Radiesse Injectable Dermal Filler | 0 |
Number Participants With Hypertropic Scarring, Keloid Formation, Hyper- or Hypopigmentation in Patients With Fitzpatrick Skin Types IV, V, and VI Receiving Nasolabial Fold Treatment
Skin type IV - Burns minimally, tans moderately and easily, Skin type V - Rarely burns, tans profusely; Skin type VI - Never burns, tans profusely (NCT01012388)
Timeframe: 6 months
| Intervention | participants (Number) |
|---|---|
| Radiesse Injectable Dermal Filler | 0 |
Cosmetic Outcome of the Cesarean Section Incision
"The following instruments will be used to determine the cosmetic outcome:~• The Modified Vancouver scar scale Range of scale values are from 0-12 (0 indicating a better outcome)" (NCT01697748)
Timeframe: Post operative day 7
| Intervention | score on a scale (Mean) |
|---|---|
| Telfa Pad Dressing | 3.8 |
| Silver-impregnated Dressing | 3.7 |
Cosmetic Outcome of the Cesarean Section Incision
"The following instruments will be used to determine the cosmetic outcome~• The Modified Observer Scar Assessment Scale Range of scale values is from 5 - 50 ( the lower the score the better the outcome)" (NCT01697748)
Timeframe: Six weeks post-operative
| Intervention | score on a scale (Mean) |
|---|---|
| Telfa Pad Dressing | 11.4 |
| Silver-impregnated Dressing | 11.6 |
Percentage of Patients Who Develop a Surgical Site Infection
"A surgical site infection involving the skin and subcutaneous tissue is defined as either~The presence of a purulent discharge from the wound on inspection, or~Purulent discharge obtained from the wound after exploration based on the suspicion of the provider (erythema, swelling, heat or pain), or~The presence of a seroma or hematoma discharge from the wound on inspection or after exploration that also involves isolation of an organism from an aseptically obtained culture based on suspicion of the provider (erythema, swelling, heat or pain). Seromas or hematomas with negative cultures will not be considered a surgical site infection." (NCT01697748)
Timeframe: from post operative day #1 through post operative day 30
| Intervention | Participants (Count of Participants) |
|---|---|
| Telfa Pad Dressing | 14 |
| Silver-impregnated Dressing | 15 |
Reduction of Pain After Cesarean Delivery
The amount of narcotics measured in Morphine equivalent milligrams and non opioids administered during the cesarean delivery hospitalization were recorded (NCT01697748)
Timeframe: Immediately post operatively to hospital discharge
| Intervention | Morphine milligram equivalent (Median) |
|---|---|
| Telfa Pad Dressing | 90.0 |
| Silver-impregnated Dressing | 82.5 |
The Number of Participants Noting Pain at the One Week Post Cesarean Visit
Pain response to notable pain at wound site during 7 day post operative visit Subjective self reporting pain as yes or no. (NCT01697748)
Timeframe: Post operative day 7
| Intervention | Participants (Count of Participants) |
|---|---|
| Telfa Pad Dressing | 23 |
| Silver-impregnated Dressing | 21 |
The Number of Participants Noting Pain at the Six Weeks Post Cesarean Visit
Pain response to notable pain at wound site during 6 week post operative visit Subjective self reporting of pain as yes or no. (NCT01697748)
Timeframe: 6 weeks post operative
| Intervention | Participants (Count of Participants) |
|---|---|
| Telfa Pad Dressing | 5 |
| Silver-impregnated Dressing | 8 |
Change in Lesion Cosmetic Appearance
Blinded investigator assessed the scar cosmetic appearance using a visual analog scale (VAS), ranging from 0-100 (0=best and 100=worst). (NCT00754247)
Timeframe: Assessed at Baseline visit (week 0) and week 16
| Intervention | Percent change (Mean) |
|---|---|
| 0.5% Hydrocortisone, Silicone, Vitamin E Lotion (HSE ) | 68 |
| Onion Extract Gel (OE) | 25 |
| Cetearyl Alcohol Lotion (Placebo) | 15 |
Change in Lesion Cosmetic Appearance
Subjects assessed the scar cosmetic appearance with a visual analog scale (VAS), ranging from 0-100 (0=best and 100=worst). (NCT00754247)
Timeframe: Assessed at Baseline visit (week 0) and week 16
| Intervention | Percent change (Mean) |
|---|---|
| 0.5% Hydrocortisone, Silicone, Vitamin E Lotion (HSE ) | 48 |
| Onion Extract Gel (OE) | 20 |
| Cetearyl Alcohol Lotion (Placebo) | 58 |
Change in Lesion Erythema
Blinded investigator assessed the scar erythema. Measured with a visual analog scale (VAS), ranging from 0-100 (0=best and 100=worst). (NCT00754247)
Timeframe: Assessed at Baseline visit (week 0) and week 16
| Intervention | Percent change (Mean) |
|---|---|
| 0.5% Hydrocortisone, Silicone, Vitamin E Lotion (HSE ) | 72 |
| Onion Extract Gel (OE) | 8 |
| Cetearyl Alcohol Lotion (Placebo) | 1 |
Change in Lesion Induration
Blinded investigator assessed the scar induration. Measured with a ruler at deepest point. (NCT00754247)
Timeframe: Assessed at Baseline visit (week 0) and week 16
| Intervention | Percent change (Mean) |
|---|---|
| 0.5% Hydrocortisone, Silicone, Vitamin E Lotion (HSE ) | 68 |
| Onion Extract Gel (OE) | 50 |
| Cetearyl Alcohol Lotion (Placebo) | 2 |
Change in Lesion Length
Blinded investigator assessed the scar length. Measured with ruler, from scar tip to tip. (NCT00754247)
Timeframe: Assessed at Baseline visit (week 0) and week 16
| Intervention | Percent change (Mean) |
|---|---|
| 0.5% Hydrocortisone, Silicone, Vitamin E Lotion (HSE ) | 12 |
| Onion Extract Gel (OE) | 13 |
| Cetearyl Alcohol Lotion (Placebo) | 3 |
Change in Lesion Pigmentary Alteration
Blinded investigator assessed the scar pigmentation alteration using a visual analog scale (VAS), ranging from 0-100 (0=best and 100=worst). (NCT00754247)
Timeframe: Assessed at Baseline visit (week 0) and week 16
| Intervention | Percent change (Mean) |
|---|---|
| 0.5% Hydrocortisone, Silicone, Vitamin E Lotion (HSE ) | 61 |
| Onion Extract Gel (OE) | 30 |
| Cetearyl Alcohol Lotion (Placebo) | 0 |
Change in Lesion Volume
Blinded investigator assessed the scar volume by using an alginate impression. (NCT00754247)
Timeframe: Assessed at Baseline visit (week 0) and week 16
| Intervention | Percent Change (Mean) |
|---|---|
| 0.5% Hydrocortisone, Silicone, Vitamin E Lotion (HSE ) | 40 |
| Onion Extract Gel (OE) | 42 |
| Cetearyl Alcohol Lotion (Placebo) | 32 |
Change in Lesion Width
Blinded investigator assessed the scar width. Measured with a ruler at the visually largest width. (NCT00754247)
Timeframe: Assessed at Baseline visit (week 0) and week 16
| Intervention | Percent change (Mean) |
|---|---|
| 0.5% Hydrocortisone, Silicone, Vitamin E Lotion (HSE ) | 0 |
| Onion Extract Gel (OE) | 16 |
| Cetearyl Alcohol Lotion (Placebo) | 5 |
Reviews
467 reviews available for khellin and Keloid
| Article | Year |
|---|---|
Letter to the Editor: Evaluation of Efficacy of Corticosteroid and Corticosteroid Combined with Botulinum Toxin Type A in the Treatment of Keloid and Hypertrophic Scars-A Meta-Analysis.
Topics: Adrenal Cortex Hormones; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Humans; Injections, Intra | 2022 |
Novel targets and therapies for keloid.
Topics: Esthetics; Humans; Keloid; Quality of Life; Recurrence; Stress, Psychological | 2022 |
Pruritus in Keloid Scars: Mechanisms and Treatments.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Humans; Keloid; Pain; Pruritus; Quality of Life | 2021 |
Emerging insights into the immunological aspects of keloids.
Topics: Fibroblasts; Humans; Inflammation; Keloid | 2021 |
Molecular Features of Hypertrophic Scars After Thermal Injury: Is There a Biologic Basis for Laser Therapy?
Topics: Animals; Biological Products; Burns; Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy | 2022 |
The Role of Interleukin 10 in Keloid Therapy: A Literature Review.
Topics: Animals; Cytokines; Fibroblasts; Humans; Interleukin-10; Keloid; Wound Healing | 2022 |
The Most Current Algorithms for the Treatment and Prevention of Hypertrophic Scars and Keloids: A 2020 Update of the Algorithms Published 10 Years Ago.
Topics: Aftercare; Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Humans; Keloid; Pos | 2022 |
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid; Models, Animal; Skin; Wound Healing | 2023 |
Efficacy of the Neodymium-Doped Yttrium Aluminum Garnet Laser in the Treatment of Keloid and Hypertrophic Scars: A Systematic Review and Meta-analysis.
Topics: Aluminum; Cicatrix, Hypertrophic; Humans; Keloid; Lasers, Solid-State; Neodymium; Quality of Life; T | 2022 |
Management of hypertrophic scars in adults: A systematic review and meta-analysis.
Topics: Adult; Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Silicones; Treatment Outcome; Triamcino | 2022 |
Assorted Skin Procedures: Foreign Body Removal, Cryotherapy, Electrosurgery, and Treatment of Keloids.
Topics: Cryosurgery; Cryotherapy; Electrosurgery; Foreign Bodies; Humans; Keloid | 2022 |
Fine Regulation during Wound Healing by Mast Cells, a Physiological Role Not Yet Clarified.
Topics: Cytokines; Humans; Inflammation; Keloid; Mast Cells; Wound Healing | 2022 |
Surgical considerations in skin of colour: minimizing pathological scars.
Topics: Cicatrix, Hypertrophic; Humans; Hypertrophy; Keloid; Skin; Skin Pigmentation; Wound Healing | 2022 |
Remarkable efficiency of surgical shave excision of keloids followed by intralesional injection of Bleomycin. A retrospective study of 314 cases.
Topics: Adult; Bleomycin; Humans; Injections, Intralesional; Keloid; Middle Aged; Pain; Pruritus; Retrospect | 2022 |
The use of fluid silicone gels in the prevention and treatment of hypertrophic scars: a systematic review and meta-analysis.
Topics: Burns; Cicatrix, Hypertrophic; Gels; Humans; Keloid; Silicone Gels | 2022 |
[Research advances on the influence of poor dietary habits on the development of keloids].
Topics: Diet; Feeding Behavior; Humans; Inflammation; Keloid; NF-kappa B; Tumor Necrosis Factor-alpha | 2022 |
Galectin 1-A Key Player between Tissue Repair and Fibrosis.
Topics: Fibrosis; Galectin 1; Humans; Keloid; Phosphatidylinositol 3-Kinases; Wound Healing | 2022 |
Off-Label Use of Botulinum Toxin in Dermatology-Current State of the Art.
Topics: Dermatology; Humans; Keloid; Neurotoxins; Off-Label Use; United States | 2022 |
Controlling Inflammation Pre-Emptively or at the Time of Cutaneous Injury Optimises Outcome of Skin Scarring.
Topics: Cicatrix, Hypertrophic; Humans; Inflammation; Keloid; Skin; Skin Diseases; Wound Healing | 2022 |
Role of Inflammasomes in Keloids and Hypertrophic Scars-Lessons Learned from Chronic Diabetic Wounds and Skin Fibrosis.
Topics: Cicatrix, Hypertrophic; Diabetes Mellitus; Endothelial Cells; Fibrosis; Humans; Inflammasomes; Infla | 2022 |
[Prevention and treatment of keloids].
Topics: Antacids; Collagen; Humans; Keloid; Penicillins; Recurrence | 2022 |
Radiation therapy modalities for keloid management: A critical review.
Topics: Combined Modality Therapy; Humans; Keloid; Prospective Studies; Radiotherapy, Adjuvant; Recurrence; | 2022 |
Mechanomodulatory biomaterials prospects in scar prevention and treatment.
Topics: Biocompatible Materials; Cicatrix, Hypertrophic; Humans; Keloid; Mechanotransduction, Cellular; Skin | 2022 |
Keloid: Genetic susceptibility and contributions of genetics and epigenetics to its pathogenesis.
Topics: DNA Methylation; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Keloid; Mal | 2022 |
Laser therapy for treating hypertrophic and keloid scars.
Topics: Adrenal Cortex Hormones; Adult; Aluminum; Atrophy; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Di | 2022 |
Laser-Assisted Drug Delivery in the Treatment of Scars, Rhytids, and Melasma: A Comprehensive Review of the Literature.
Topics: Administration, Cutaneous; Humans; Keloid; Lasers; Melanosis; Pharmaceutical Preparations; Treatment | 2023 |
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin.
Topics: Cell Proliferation; Collagen; Fibronectins; Fibrosis; Humans; Keloid; Skin; Transcriptome | 2023 |
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin.
Topics: Cell Proliferation; Collagen; Fibronectins; Fibrosis; Humans; Keloid; Skin; Transcriptome | 2023 |
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin.
Topics: Cell Proliferation; Collagen; Fibronectins; Fibrosis; Humans; Keloid; Skin; Transcriptome | 2023 |
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin.
Topics: Cell Proliferation; Collagen; Fibronectins; Fibrosis; Humans; Keloid; Skin; Transcriptome | 2023 |
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin.
Topics: Cell Proliferation; Collagen; Fibronectins; Fibrosis; Humans; Keloid; Skin; Transcriptome | 2023 |
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin.
Topics: Cell Proliferation; Collagen; Fibronectins; Fibrosis; Humans; Keloid; Skin; Transcriptome | 2023 |
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin.
Topics: Cell Proliferation; Collagen; Fibronectins; Fibrosis; Humans; Keloid; Skin; Transcriptome | 2023 |
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin.
Topics: Cell Proliferation; Collagen; Fibronectins; Fibrosis; Humans; Keloid; Skin; Transcriptome | 2023 |
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin.
Topics: Cell Proliferation; Collagen; Fibronectins; Fibrosis; Humans; Keloid; Skin; Transcriptome | 2023 |
Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis.
Topics: Cicatrix, Hypertrophic; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis.
Topics: Cicatrix, Hypertrophic; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis.
Topics: Cicatrix, Hypertrophic; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Keloid disease: Review with clinical atlas. Part I: Definitions, history, epidemiology, clinics and diagnosis.
Topics: Cicatrix, Hypertrophic; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Evidence-based management of keloids and hypertrophic scars in dermatology.
Topics: Cicatrix, Hypertrophic; Dermatology; Humans; Keloid; Skin; Wound Healing | 2023 |
Evidence-based management of keloids and hypertrophic scars in dermatology.
Topics: Cicatrix, Hypertrophic; Dermatology; Humans; Keloid; Skin; Wound Healing | 2023 |
Evidence-based management of keloids and hypertrophic scars in dermatology.
Topics: Cicatrix, Hypertrophic; Dermatology; Humans; Keloid; Skin; Wound Healing | 2023 |
Evidence-based management of keloids and hypertrophic scars in dermatology.
Topics: Cicatrix, Hypertrophic; Dermatology; Humans; Keloid; Skin; Wound Healing | 2023 |
Comparing the Efficacy of Multiple Drugs Injection for the Treatment of Hypertrophic Scars and Keloid: A Network Meta-Analysis.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Network Meta-Analysis; Treatment Outcome | 2023 |
Inflammation in Wound Healing and Pathological Scarring.
Topics: Cicatrix, Hypertrophic; Humans; Inflammation; Keloid; Quality of Life; Wound Healing | 2023 |
Immune cells and associated molecular markers in dermal fibrosis with focus on raised cutaneous scars.
Topics: Cicatrix, Hypertrophic; Cytokines; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Keloid | 2023 |
Efficacy and Safety of Verapamil Versus Triamcinolone Acetonide in Treating Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as T | 2023 |
[Inflammatory dermatoses in skin of color].
Topics: Acne Vulgaris; Dermatitis, Atopic; Humans; Hyperpigmentation; Keloid; Psoriasis; Rosacea; Skin Pigme | 2023 |
Silicone gel sheeting for treating keloid scars.
Topics: Bandages; Humans; Keloid; Randomized Controlled Trials as Topic; Silicone Gels; Triamcinolone Aceton | 2023 |
Intralesional corticosteroid administration in the treatment of keloids: a survey among Dutch dermatologists and plastic surgeons.
Topics: Dermatologists; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Surgeons; Treatment Outc | 2023 |
Relationship between asporin and extracellular matrix behavior: A literature review.
Topics: Animals; Extracellular Matrix; Extracellular Matrix Proteins; Humans; Keloid; Mice | 2022 |
The JAK-STAT pathway in keloid pathogenesis: a systematic review with qualitative synthesis.
Topics: Cytokines; Humans; Janus Kinases; Keloid; Signal Transduction; STAT Transcription Factors | 2023 |
[Aspects of esthetic dermatology on skin of color].
Topics: Dermatology; Esthetics; Humans; Keloid; Skin; Skin Pigmentation | 2023 |
Intralesional Corticosteroid Administration in the Treatment of Keloids: A Scoping Review on Injection Methods.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Randomized Contr | 2023 |
Hypertrophic Scars and Keloids: Advances in Treatment and Review of Established Therapies.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Humans; Keloid; Skin; Wound Healing | 2023 |
Role of HIF-1α in pathogenic mechanisms of keloids.
Topics: Collagen; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Keloid; Signal Transduction | 2023 |
Epidermal Potentiation of Dermal Fibrosis: Lessons from Occlusion and Mucosal Healing.
Topics: Cicatrix, Hypertrophic; Epidermis; Fibrosis; Humans; Keloid; Skin; Wound Healing | 2023 |
Treatment of traumatic hypertrophic scars and keloids: a systematic review of randomized control trials.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Hypertrophy; Injections, Intralesional; Keloid; Qualit | 2023 |
Evaluation of the Risk of Hypertrophic Scarring and Keloid Following Eyelid Procedures: A Systematic Review.
Topics: Blepharoplasty; Cicatrix, Hypertrophic; Eyelids; Humans; Keloid | 2023 |
Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology-a systematic review.
Topics: Acne Vulgaris; Dermatology; Fluorouracil; Humans; Keloid; Treatment Outcome; Triamcinolone Acetonide | 2023 |
Keloid treatments: an evidence-based systematic review of recent advances.
Topics: Adrenal Cortex Hormones; Fluorouracil; Humans; Keloid; Prospective Studies; Treatment Outcome; Verap | 2023 |
Reducing Risks of Facial Scarring.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Reoperation; Skin; Wound Healing | 2023 |
An updated review of the immunological mechanisms of keloid scars.
Topics: Collagen; Fibroblasts; Humans; Keloid; Skin; Wound Healing | 2023 |
The Role of Physical Therapies in Wound Healing and Assisted Scarring.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Physical Therapy Modalities; Pressure Ulcer; Wound Healing | 2023 |
The Role of Extracellular Matrix in Wound Healing.
Topics: Extracellular Matrix; Humans; Inflammation; Keloid; Skin; Wound Healing | 2023 |
Pediatric Keloids and Review of the Efficacy of Current Treatment Modalities.
Topics: Adolescent; Child; Cicatrix, Hypertrophic; Collagen; Combined Modality Therapy; Humans; Keloid; Woun | 2023 |
Sufficient mesh polyhedral intralesional injection for treatment of keloids.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Ropivacaine; Surgical Mesh; Treat | 2023 |
Keloids and Hypertrophic Scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid | 2023 |
Tattooing of Scars and Disfiguring Burn Lesions.
Topics: Burns; Humans; Keloid; Quality of Life; Skin; Tattooing | 2022 |
Scarring and Dyschromias in Fitzpatrick Skin Type IV-VI: A Review of Dermatologic Treatment Protocols.
Topics: Cicatrix, Hypertrophic; Clinical Protocols; Humans; Keloid; Pigmentation Disorders; Skin; Wound Heal | 2023 |
Recurrence rates in the treatment of keloids and hypertrophic scars with intralesional triamcinolone combined with other intralesional agents.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Treatment Outcome; Triamcinolone | 2023 |
Skin fibroblast functional heterogeneity in health and disease.
Topics: Fibroblasts; Humans; Keloid; Neoplasms; Skin; Wound Healing | 2023 |
Characterization of the skin keloid microenvironment.
Topics: Endothelial Cells; Epigenesis, Genetic; Humans; Keloid; Keratinocytes; Skin | 2023 |
Uterine leiomyomata and keloids fibrosis origins: a mini-review of fibroproliferative diseases.
Topics: Female; Fibrosis; Humans; Keloid; Leiomyoma; Uterus | 2023 |
Dark Skin Representation in Mobile Applications for Dermatology Education: A Scoping Review.
Topics: Dermatology; Humans; Keloid; Melanoma; Mobile Applications; Skin Neoplasms; Skin Pigmentation | 2023 |
[Research advances in the treatment of keloid with glucocorticoids].
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcome | 2023 |
Fibrosis in burns: an overview of mechanisms and therapies.
Topics: Burns; Fibrosis; Humans; Keloid; Quality of Life; Skin | 2023 |
Modelling Keloids Dynamics: A Brief Review and New Mathematical Perspectives.
Topics: Animals; Humans; Keloid; Mathematical Concepts; Models, Biological; Neoplasms; Wound Healing | 2023 |
Microneedle-mediated drug delivery for scar prevention and treatment.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Humans; Keloid; Laser Therapy; Wound Healing | 2023 |
Analysis of Risk Factors to Predict Occurrence and Prognosis of Postsurgical Hypertrophic Scar Development: A Review of 4238 Cases.
Topics: Body Mass Index; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; Prognosis; Risk Factors | 2023 |
The Communication from Immune Cells to the Fibroblasts in Keloids: Implications for Immunotherapy.
Topics: Cells, Cultured; Collagen; Communication; Fibroblasts; Humans; Immunotherapy; Keloid; Quality of Lif | 2023 |
A systematic review of the management of postoperative scars with silicone gel-based products in randomized controlled trials.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Quality of Life; Randomized Controlled Trials as Topic; Sili | 2023 |
Scars.
Topics: Cicatrix, Hypertrophic; Fibrosis; Humans; Keloid; Skin; Wound Healing | 2023 |
Understanding Keloid Pathobiology From a Quasi-Neoplastic Perspective: Less of a Scar and More of a Chronic Inflammatory Disease With Cancer-Like Tendencies.
Topics: Animals; Chronic Disease; Humans; Inflammation; Keloid; Neoplasms | 2019 |
Disease Severity and Quality of Life Outcome Measurements in Patients With Keloids: A Systematic Review.
Topics: Humans; Keloid; Patient Reported Outcome Measures; Quality of Life; Randomized Controlled Trials as | 2019 |
Imiquimod to prevent keloid recurrence postexcision: A systematic review and meta-analysis.
Topics: Adjuvants, Immunologic; Administration, Cutaneous; Dermatologic Surgical Procedures; Humans; Imiquim | 2020 |
Comparative Efficacy and Safety of Common Therapies in Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis.
Topics: Bayes Theorem; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Treatment Outcome | 2020 |
Radiation Therapy for Benign Disease: Keloids, Macular Degeneration, Orbital Pseudotumor, Pterygium, Peyronie Disease, Trigeminal Neuralgia.
Topics: Conjunctiva; Humans; Keloid; Macular Degeneration; Male; Orbital Pseudotumor; Penile Induration; Pte | 2020 |
An atypical keloid in a Brazilian man.
Topics: Brazil; Diagnosis, Differential; French Guiana; Humans; Keloid; Lacazia; Lobomycosis; Male; Middle A | 2019 |
Artificial Intelligence in Plastic Surgery: Applications and Challenges.
Topics: Artificial Intelligence; Evidence-Based Medicine; Humans; Keloid; Plastic Surgery Procedures; Surger | 2021 |
Topical stabilized hypochlorous acid: The future gold standard for wound care and scar management in dermatologic and plastic surgery procedures.
Topics: Administration, Cutaneous; Anti-Infective Agents, Local; Biofilms; Cicatrix, Hypertrophic; Humans; H | 2020 |
Keloid scarring or disease: Unresolved quasi-neoplastic tendencies in the human skin.
Topics: Humans; Keloid; Skin Neoplasms | 2020 |
Efficacy and tolerability of intralesional bleomycin in dermatology: A systematic review.
Topics: Bleomycin; Cicatrix, Hypertrophic; Erythema; Hemangioma; Humans; Injections, Intralesional; Keloid; | 2020 |
Keloid and Hypertrophic Scar Formation, Prevention, and Management: Standard Review of Abnormal Scarring in Orthopaedic Surgery.
Topics: Cicatrix; Glucocorticoids; Humans; Keloid; Laser Therapy; Orthopedic Procedures; Radiotherapy; Recur | 2020 |
Morphea With Keloidal Features: A Case Report and Review of the Literature.
Topics: Adult; Antibodies, Antinuclear; Biopsy; Diagnosis, Differential; Erythema; Female; Humans; Hyperpigm | 2020 |
The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis.
Topics: Calcium Channel Blockers; Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional | 2020 |
The Efficacy of Surgical Excision Plus Adjuvant Multimodal Therapies in the Treatment of Keloids: A Systematic Review and Meta-Analysis.
Topics: Anti-Inflammatory Agents; Chemotherapy, Adjuvant; Combined Modality Therapy; Dermatologic Surgical P | 2020 |
The efficacy of bleomycin for treating keloid and hypertrophic scar: A systematic review and meta-analysis.
Topics: Bleomycin; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Treatment Outcome | 2020 |
Efficacy and Safety of Intralesional Triamcinolone Versus Combination of Triamcinolone with 5-Fluorouracil in the Treatment of Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis.
Topics: Cicatrix, Hypertrophic; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intralesional; | 2020 |
Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; Verapami | 2020 |
Interplay Between Keratinocytes and Fibroblasts: A Systematic Review Providing a New Angle for Understanding Skin Fibrotic Disorders.
Topics: Animals; Cicatrix, Hypertrophic; Fibroblasts; Fibrosis; Humans; Keloid; Keratinocytes; Scleroderma, | 2020 |
Hypertrophic scars and keloids: Overview of the evidence and practical guide for differentiating between these abnormal scars.
Topics: Actins; Cicatrix, Hypertrophic; Collagen; Diagnosis, Differential; Humans; Keloid | 2021 |
IMPROVEMENT OF HYPERTROPHIC SCARS WITH INTRALESION INJECTIONS OF HYALURONIDASE.
Topics: Cicatrix, Hypertrophic; Humans; Hyaluronoglucosaminidase; Injections, Intralesional; Keloid; Wound H | 2020 |
Current potential therapeutic strategies targeting the TGF-β/Smad signaling pathway to attenuate keloid and hypertrophic scar formation.
Topics: Animals; Cell- and Tissue-Based Therapy; Cicatrix, Hypertrophic; Dermatologic Agents; Genetic Therap | 2020 |
Alternative Clinical Indications of Botulinum Toxin.
Topics: Acetylcholine Release Inhibitors; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Dermatology; Hid | 2020 |
The Latest Strategy for Keloid and Hypertrophic Scar Prevention and Treatment: The Nippon Medical School (NMS) Protocol.
Topics: Adrenal Cortex Hormones; Algorithms; Cicatrix, Hypertrophic; Combined Modality Therapy; Evidence-Bas | 2021 |
Nonsurgical Management of Hypertrophic Scars: Evidence-Based Therapies, Standard Practices, and Emerging Methods.
Topics: Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid; Recurrence; Reference Standards | 2020 |
Improvement of Burn Scars Treated With Fractional Ablative CO2 Lasers-A Systematic Review and Meta-analysis Using the Vancouver Scar Scale.
Topics: Burns; Cicatrix, Hypertrophic; Follow-Up Studies; Humans; Keloid; Lasers, Gas; Regeneration; Treatme | 2021 |
Keloids: a review of therapeutic management.
Topics: Fluorouracil; Humans; Injections, Intralesional; Keloid; Recurrence; Steroids | 2021 |
Drug delivery to optimize angiogenesis imbalance in keloid: A review.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Pharmaceutical Preparations; Skin; Wound Healing | 2021 |
Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseases.
Topics: Animals; Cell Differentiation; Cell Transdifferentiation; Extracellular Matrix; Fibroblasts; Fibrone | 2021 |
Epigenetic modification mechanisms involved in keloid: current status and prospect.
Topics: Animals; Apoptosis; Cell Proliferation; CpG Islands; DNA Methylation; Epigenesis, Genetic; Epigenomi | 2020 |
Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as T | 2021 |
The Roles of Inflammation in Keloid and Hypertrophic Scars.
Topics: Animals; Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Collagen; Cytokines; Dermatologic Agents; | 2020 |
A Review of the Evidence for and against a Role for Mast Cells in Cutaneous Scarring and Fibrosis.
Topics: Animals; Biomarkers; Cell Communication; Cicatrix; Cicatrix, Hypertrophic; Disease Models, Animal; D | 2020 |
[Meta-analysis of the effects of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating keloids].
Topics: Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2020 |
Mesenchymal stem cell therapy in hypertrophic and keloid scars.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid; Mesenchymal Stem Cell Transplantation; Treatment Ou | 2021 |
Chest keloids: effect of surgical excision and adjuvant radiotherapy on recurrence, a systematic review and meta-analysis.
Topics: Humans; Keloid; Neoplasm Recurrence, Local; Prospective Studies; Radiotherapy, Adjuvant; Randomized | 2021 |
Dermal Fibroblast Heterogeneity and Its Contribution to the Skin Repair and Regeneration.
Topics: Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid; Skin; Wound Healing | 2022 |
Laser treatment of specific scar characteristics in hypertrophic scars and keloid: A systematic review.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy | 2021 |
[Current dermatology guidelines in Germany and Europe : A selection of clinically relevant recommendations].
Topics: Dermatology; Europe; Germany; Humans; Keloid; Lichen Planus | 2021 |
A systematic review of randomised controlled trials investigating laser assisted drug delivery for the treatment of keloid and hypertrophic scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Lasers; Pharmaceutical Preparations; Randomized Controlled T | 2022 |
Emerging and Novel Therapies for Keloids: A compendious review.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy; Silicone Gels | 2021 |
The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
Topics: Atrophy; Burns; Cicatrix, Hypertrophic; Culture Media; Fluorouracil; Humans; Injections, Intralesion | 2021 |
A Scoping Review of the Methodology Used in Studies of Genetic Influences on the Development of Keloid or Hypertrophic Scarring in Adults and Children After Acute Wounding.
Topics: Burns; Cicatrix, Hypertrophic; Genome-Wide Association Study; Humans; Keloid; Polymorphism, Single N | 2021 |
A Review of Hypertrophic Scar and Keloid Treatment and Prevention in the Pediatric Population: Where Are We Now?
Topics: Animals; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Humans; Keloid; Lasers, Gas; Reproducibility | 2022 |
Therapeutic candidates for keloid scars identified by qualitative review of scratch assay research for wound healing.
Topics: Biological Assay; Cell Movement; Cell Proliferation; Humans; Keloid; Wound Healing | 2021 |
The epigenetics of keloids.
Topics: Cellular Reprogramming; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histones; | 2021 |
Update on management of keloid and hypertrophic scars: A systemic review.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Recurrence | 2021 |
Evaluation of Efficacy of Corticosteroid and Corticosteroid Combined with Botulinum Toxin Type A in the Treatment of Keloid and Hypertrophic Scars: A Meta-Analysis.
Topics: Adrenal Cortex Hormones; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Humans; Injections, Intra | 2021 |
Validation strategies for identifying drug targets in dermal fibrotic disorders.
Topics: Animals; Drug Development; Drug Discovery; Fibrosis; Humans; Keloid; Molecular Targeted Therapy; Ski | 2021 |
Treatment of keloids and hypertrophic scars. Position statement of the Brazilian expert group GREMCIQ.
Topics: Brazil; Cicatrix, Hypertrophic; Humans; Keloid | 2021 |
Comparative efficacy and safety of verapamil and triamcinolone in keloid and hypertrophic scar treatment: a meta-analysis.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone | 2021 |
Efficacy and safety of laser combination therapy and laser alone therapy for keloid: a systematic review and meta-analysis.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy; Lasers; Low-Level Light Therapy | 2022 |
Common Dermatologic Procedures and the Associated Complications Unique to Skin of Color.
Topics: Chemexfoliation; Cosmetic Techniques; Dermatologic Surgical Procedures; Dry Needling; Humans; Hyperp | 2021 |
Adjuvant Radiotherapy after Surgical Excision in Keloids.
Topics: Combined Modality Therapy; Humans; Keloid; Quality of Life; Radiotherapy, Adjuvant; Recurrence; Trea | 2021 |
Adjuvant Radiotherapy for Keloids.
Topics: Humans; Keloid; Radiotherapy, Adjuvant | 2022 |
Timing of Adjuvant Radiotherapy After Keloid Excision: A Systematic Review and Meta-Analysis.
Topics: Humans; Keloid; Radiotherapy, Adjuvant; Time Factors | 2021 |
Keloids on the ears.
Topics: Adult; Biopsy, Needle; Colombia; Cryosurgery; Disease Progression; Ear, External; Endemic Diseases; | 2017 |
Safety and Patient Satisfaction of AbobotulinumtoxinA for Aesthetic Use: A Systematic Review.
Topics: Antibodies, Neutralizing; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Clinical Trials as Topic | 2017 |
Association of surgical excision and brachytherapy for the management of keloids.
Topics: Brachytherapy; Combined Modality Therapy; Face; Humans; Keloid; Plastic Surgery Procedures; Radiothe | 2017 |
Review of Silicone Gel Sheeting and Silicone Gel for the Prevention of Hypertrophic Scars and Keloids.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2017 |
Sonodynamic therapy, a treatment developing from photodynamic therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Atherosclerosis; Dendriti | 2017 |
Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication.
Topics: Brachytherapy; Humans; Keloid; Radiotherapy; Treatment Outcome | 2017 |
MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment.
Topics: Cicatrix, Hypertrophic; Fibrosis; Gene Expression Regulation; Humans; Keloid; MicroRNAs; Molecular T | 2017 |
Advances in Mechanisms for Prevention and Treatment of Pathological Scars with Mesenchymal Stem Cells.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Mesenchymal Stem Cells; Quality of Life; Wound Healing | 2017 |
The Importance of Patient Registries in Skin of Color.
Topics: Disease Progression; Humans; Keloid; Quality of Life; Registries; Skin Pigmentation; Vitiligo | 2017 |
Current Understanding of the Genetic Causes of Keloid Formation.
Topics: Asian People; Black People; Epigenesis, Genetic; Genetic Loci; Genetic Predisposition to Disease; HL | 2017 |
Treatment of keloid scars using light-, laser- and energy-based devices: a contemporary review of the literature.
Topics: Cicatrix, Hypertrophic; Drug Delivery Systems; Ethnicity; Humans; Keloid; Lasers; Light; Skin | 2017 |
How Signaling Molecules Regulate Tumor Microenvironment: Parallels to Wound Repair.
Topics: Animals; Cellular Microenvironment; Cytokines; Galectins; Humans; Immune System; Intercellular Signa | 2017 |
[Therapy of scars with lasers].
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy; Lasers, Dye; Lasers, Solid-State | 2018 |
Advances in fractional technology for skin rejuvenation, skin tightening, drug delivery, and treating scars and skin defects.
Topics: Administration, Cutaneous; Cicatrix; Cicatrix, Hypertrophic; Cosmetic Techniques; Drug Delivery Syst | 2017 |
Insights into the Pathophysiology of Hypertrophic Scars and Keloids: How Do They Differ?
Topics: Biopsy, Needle; Cicatrix, Hypertrophic; Collagen; Combined Modality Therapy; Diagnosis, Differential | 2018 |
[Advances in the research of relationship between CD26 and hypertrophic scar and keloid].
Topics: Cicatrix, Hypertrophic; Dipeptidyl Peptidase 4; Fibrosis; Humans; Keloid | 2018 |
The Cellular Response of Keloids and Hypertrophic Scars to Botulinum Toxin A: A Comprehensive Literature Review.
Topics: Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Humans; Keloid; Neuromuscular Agents | 2018 |
[How to optimize scarring in dermatologic surgery?]
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Cicatrix; Cicatrix, Hypertrophic; Combined Modali | 2016 |
Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids.
Topics: Biomarkers; Cicatrix, Hypertrophic; Combined Modality Therapy; Cytokines; Extracellular Matrix; Huma | 2018 |
Facial Plastic Surgery Controversies: Keloids.
Topics: Face; Humans; Keloid; Plastic Surgery Procedures; Surgery, Plastic | 2018 |
[Advances in the research of drug intralesional injection therapy in keloid].
Topics: Female; Humans; Injections, Intralesional; Keloid; Pain | 2018 |
Spontaneous Keloids: A Literature Review.
Topics: Humans; Keloid | 2018 |
Current and upcoming therapies to modulate skin scarring and fibrosis.
Topics: Animals; Cicatrix, Hypertrophic; Fibrosis; Humans; Inflammation; Keloid; Skin Diseases | 2019 |
Patient-reported outcomes for keloids: a systematic review.
Topics: Brachytherapy; Combined Modality Therapy; Cryotherapy; Humans; Keloid; Patient Reported Outcome Meas | 2019 |
Botulinum toxin type A for the treatment and prevention of hypertrophic scars and keloids: Updated review.
Topics: Botulinum Toxins, Type A; Cell Cycle; Cicatrix, Hypertrophic; Fibroblasts; Gene Expression; Humans; | 2019 |
Abnormal Presentation of Aggressive Fibromatosis After Radiotherapy for Keloids: Case Report and Brief Literature Review.
Topics: Adolescent; Biopsy, Needle; Female; Fibromatosis, Aggressive; Follow-Up Studies; Humans; Immunohisto | 2019 |
Advances in diagnostic methods for keloids and biomarker-targeted fluorescent probes.
Topics: Biomarkers; Fluorescent Dyes; Humans; Keloid | 2019 |
Managing keloid scars: From radiation therapy to actual and potential drug deliveries.
Topics: Adult; Aged; Aged, 80 and over; Cicatrix, Hypertrophic; Drug Therapy; Female; Humans; Keloid; Male; | 2019 |
Skin tissue regeneration for burn injury.
Topics: Burns; Cicatrix, Hypertrophic; Epidermis; Humans; Keloid; Regeneration; Regenerative Medicine; Wound | 2019 |
Intralesional Injection of Botulinum Toxin Type A Compared with Intralesional Injection of Corticosteroid for the Treatment of Hypertrophic Scar and Keloid: A Systematic Review and Meta-Analysis.
Topics: Adrenal Cortex Hormones; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Humans; Injections, Intra | 2019 |
Dermatologic Conditions in Transgender Populations.
Topics: Acne Vulgaris; Alopecia; Hirsutism; Hormone Replacement Therapy; Humans; Keloid; Sex Reassignment Pr | 2019 |
Epithelial-mesenchymal transition in the formation of hypertrophic scars and keloids.
Topics: Animals; Cicatrix, Hypertrophic; Epithelial-Mesenchymal Transition; Humans; Keloid; Wound Healing | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Regeneration of Dermis: Scarring and Cells Involved.
Topics: Animals; Cicatrix; Dermis; Extracellular Matrix; Fibroblasts; Hair Follicle; Humans; Keloid; Myofibr | 2019 |
Toward understanding scarless skin wound healing and pathological scarring.
Topics: Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid; Skin; Wound Healing | 2019 |
Keloid Excision and Adjuvant Treatments: A Network Meta-analysis.
Topics: Bayes Theorem; Chemotherapy, Adjuvant; Humans; Keloid; Radiotherapy, Adjuvant; Recurrence | 2019 |
Roles of lipid metabolism in keloid development.
Topics: Cicatrix; Fibroblasts; Humans; Inflammation; Keloid; Lipid Metabolism; Mechanotransduction, Cellular | 2013 |
Keloids: Which treatment is best for your patient?
Topics: Humans; Keloid | 2013 |
Mast cell activity in the healing wound: more than meets the eye?
Topics: Animals; Anti-Inflammatory Agents; Humans; Immunity, Innate; Inflammation; Keloid; Mast Cells; Neova | 2013 |
Mitomycin C in the treatment of keloids: a case and review.
Topics: Adult; Alkylating Agents; Female; Follow-Up Studies; Humans; Keloid; Mitomycin; Off-Label Use | 2013 |
Pharmacological treatment for keloids.
Topics: Animals; Extracellular Matrix; Fibroblasts; Humans; Keloid | 2013 |
The role of microRNAs in skin fibrosis.
Topics: Cell Differentiation; Cell Proliferation; Humans; Keloid; MicroRNAs; Oligonucleotides; Scleroderma, | 2013 |
Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2013 |
Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2013 |
Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2013 |
Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2013 |
Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2013 |
Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2013 |
Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2013 |
Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2013 |
Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2013 |
Laser and light-based treatment of Keloids--a review.
Topics: Humans; Keloid; Laser Therapy; Phototherapy | 2014 |
Pathological niche environment transforms dermal stem cells to keloid stem cells: a hypothesis of keloid formation and development.
Topics: Humans; Keloid; Models, Biological; Neoplastic Stem Cells; Skin | 2013 |
Strategic management of keloid disease in ethnic skin: a structured approach supported by the emerging literature.
Topics: Aminoquinolines; Bleomycin; Cryosurgery; Dermatologic Agents; Electric Stimulation; Fluorouracil; Hu | 2013 |
Proliferative vitreoretinopathy after eye injuries: an overexpression of growth factors and cytokines leading to a retinal keloid.
Topics: Animals; Cytokines; Eye Injuries; Gene Expression Regulation; Humans; Intercellular Signaling Peptid | 2013 |
Laser therapy for prevention and treatment of pathologic excessive scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy; Secondary Prevention | 2013 |
Intralesional treatment for keloids and hypertrophic scars: a review.
Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Antimetabolites; Bleomycin; Calcium Channel Bl | 2013 |
[Advances in the research of the effect of toll-like receptor in the formation of keloid].
Topics: Animals; Humans; Keloid; Toll-Like Receptors; Wound Healing | 2013 |
New molecular medicine-based scar management strategies.
Topics: Cicatrix, Hypertrophic; Humans; Keloid | 2014 |
Application of intense pulsed light in the treatment of dermatologic disease: a systematic review.
Topics: Bowen's Disease; Cicatrix, Hypertrophic; Evidence-Based Medicine; Humans; Intense Pulsed Light Thera | 2014 |
[Functional and aesthetic therapy concepts of keloids in the head- and neck area].
Topics: Combined Modality Therapy; Cooperative Behavior; Esthetics; Face; Humans; Interdisciplinary Communic | 2014 |
New insights on keloids, hypertrophic scars, and striae.
Topics: Anti-Inflammatory Agents; Black People; Cicatrix, Hypertrophic; Combined Modality Therapy; Humans; K | 2014 |
Human hypertrophic and keloid scar models: principles, limitations and future challenges from a tissue engineering perspective.
Topics: Animals; Cells, Cultured; Cicatrix, Hypertrophic; Humans; In Vitro Techniques; Keloid; Mice; Models, | 2014 |
Up-to-date approach to manage keloids and hypertrophic scars: a useful guide.
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Aminoquinolines; Anti-Inflammatory Agents; Antineop | 2014 |
Updated scar management practical guidelines: non-invasive and invasive measures.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Compression Bandages; Cryotherapy; Humans; Injectio | 2014 |
Updated scar management practical guidelines: non-invasive and invasive measures.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Compression Bandages; Cryotherapy; Humans; Injectio | 2014 |
Updated scar management practical guidelines: non-invasive and invasive measures.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Compression Bandages; Cryotherapy; Humans; Injectio | 2014 |
Updated scar management practical guidelines: non-invasive and invasive measures.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Compression Bandages; Cryotherapy; Humans; Injectio | 2014 |
Overview of surgical scar prevention and management.
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Sebaceous Glands; Skin; Wound Healing | 2014 |
Scar treatment variations by skin type.
Topics: Burns; Cicatrix; Cicatrix, Hypertrophic; Health Status; Humans; Intense Pulsed Light Therapy; Keloid | 2014 |
Keloids in Rubinstein-Taybi syndrome: a clinical study.
Topics: Age of Onset; Cohort Studies; Female; Humans; Keloid; Male; Rubinstein-Taybi Syndrome; Surveys and Q | 2014 |
Update on hypertrophic scar treatment.
Topics: Adrenal Cortex Hormones; Bleomycin; Cicatrix, Hypertrophic; Gravity Suits; Humans; Injections, Intra | 2014 |
Recruitment of Yoruba families from Nigeria for genetic research: experience from a multisite keloid study.
Topics: Black People; Community-Based Participatory Research; Culture; Ethics, Research; Family; Genetic Res | 2014 |
Molecular signalings in keloid disease and current therapeutic approaches from natural based compounds.
Topics: Animals; Biological Products; Humans; Keloid; Mitogen-Activated Protein Kinases; Signal Transduction | 2015 |
[Therapy of hypertrophic scars and keloids].
Topics: Administration, Topical; Cicatrix, Hypertrophic; Combined Modality Therapy; Compression Bandages; Cr | 2014 |
Intralesional 5-fluorouracil in keloid treatment: a systematic review.
Topics: Dermatologic Agents; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Glucocor | 2015 |
Update on botulinum neurotoxin use in aesthetic dermatology.
Topics: Administration, Topical; Botulinum Toxins, Type A; Cosmetic Techniques; Hot Flashes; Humans; Injecti | 2014 |
Functional histopathology of keloid disease.
Topics: Humans; Keloid | 2015 |
[Topical Preparations for Prevention and Treatment of Hypertrophic Scars and Keloids: A Literature Review].
Topics: Administration, Cutaneous; Cicatrix, Hypertrophic; Dermatologic Agents; Drug Combinations; Esthetics | 2015 |
[Ear keloid and clinical research progress].
Topics: Cell Proliferation; Ear; Ear Diseases; Fibroblasts; Humans; Keloid | 2014 |
[Scar prophylaxis and treatment].
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Practice Guidelines as Topic | 2015 |
microRNA deregulation in keloids: an opportunity for clinical intervention?
Topics: Cell Proliferation; Extracellular Matrix; Humans; Keloid; MicroRNAs; Wound Healing | 2015 |
What is the role of intralesional corticosteroid injections for keloids before considering surgery?
Topics: Adrenal Cortex Hormones; Combined Modality Therapy; Evidence-Based Medicine; Female; Follow-Up Studi | 2016 |
Could 5-Fluorouracil or Triamcinolone Be an Effective Treatment Option for Keloid After Surgical Excision? A Meta-Analysis.
Topics: Antimetabolites; Fluorouracil; Glucocorticoids; Humans; Keloid; Treatment Outcome; Triamcinolone | 2016 |
[Keloid scars (part I): Clinical presentation, epidemiology, histology and pathogenesis].
Topics: Apoptosis; Collagen; Fibroblasts; Humans; Keloid; Risk Factors; Transforming Growth Factor beta | 2016 |
Mechanism of Action, Efficacy, and Adverse Events of Calcium Antagonists in Hypertrophic Scars and Keloids: A Systematic Review.
Topics: Calcium Channel Blockers; Cicatrix, Hypertrophic; Humans; Keloid; Verapamil | 2015 |
Keloids: Animal models and pathologic equivalents to study tissue fibrosis.
Topics: Animals; Cicatrix, Hypertrophic; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Keloid; Mice | 2016 |
Keloids: The paradigm of skin fibrosis - Pathomechanisms and treatment.
Topics: Collagen; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Keloid; Skin; Steroids; Wound Healing | 2016 |
Keloids and Hypertrophic Scars: A Spectrum of Clinical Challenges.
Topics: Adjuvants, Immunologic; Aminoquinolines; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Anti | 2016 |
Current options for the treatment of pathological scarring.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Humans; Keloid; Laser Therapy | 2016 |
Current options for the treatment of pathological scarring.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Humans; Keloid; Laser Therapy | 2016 |
Current options for the treatment of pathological scarring.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Humans; Keloid; Laser Therapy | 2016 |
Current options for the treatment of pathological scarring.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Humans; Keloid; Laser Therapy | 2016 |
Acne Scar Treatment: A Multimodality Approach Tailored to Scar Type.
Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Cicatrix, Hypertrophic; Combined Modality Therapy; High-In | 2016 |
Acne Scar Treatment: A Multimodality Approach Tailored to Scar Type.
Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Cicatrix, Hypertrophic; Combined Modality Therapy; High-In | 2016 |
Acne Scar Treatment: A Multimodality Approach Tailored to Scar Type.
Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Cicatrix, Hypertrophic; Combined Modality Therapy; High-In | 2016 |
Acne Scar Treatment: A Multimodality Approach Tailored to Scar Type.
Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Cicatrix, Hypertrophic; Combined Modality Therapy; High-In | 2016 |
Advances in scar management: prevention and management of hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Humans; Keloid | 2016 |
Keloids and Hypertrophic Scars Can Now Be Cured Completely: Recent Progress in Our Understanding of the Pathogenesis of Keloids and Hypertrophic Scars and the Most Promising Current Therapeutic Strategy.
Topics: Cicatrix, Hypertrophic; Follow-Up Studies; Humans; Keloid | 2016 |
A Comparison of the Effectiveness of Triamcinolone and Radiation Therapy for Ear Keloids after Surgical Excision: A Systematic Review and Meta-Analysis.
Topics: Ear, External; Glucocorticoids; Humans; Keloid; Triamcinolone | 2016 |
Will stem cells bring hope to pathological skin scar treatment?
Topics: Animals; Cicatrix; Humans; Keloid; Regeneration; Skin; Stem Cell Transplantation; Stem Cells; Wound | 2016 |
Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Drug Therapy, Combination; Female; Fluorouracil; H | 2017 |
Dealing with tattoos in plastic surgery. Tattoo removal.
Topics: Administration, Cutaneous; Cicatrix; Cosmetic Techniques; Dermabrasion; Dermatologic Surgical Proced | 2017 |
Efficacy of 2 Representative Topical Agents to Prevent Keloid Recurrence After Surgical Excision.
Topics: Administration, Cutaneous; Aminoquinolines; Dermatologic Agents; Humans; Imiquimod; Keloid; Mitomyci | 2017 |
Treating Scars in the Auricle Region.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Cicatrix, Hypertrophic; Combined Modality Therapy; | 2017 |
[Advances in therapy of auricular keloid].
Topics: Combined Modality Therapy; Ear Auricle; Ear Diseases; Ear, External; Humans; Keloid; Recurrence | 2016 |
Evidences of autologous fat grafting for the treatment of keloids and hypertrophic scars.
Topics: Adipose Tissue; Cicatrix, Hypertrophic; Humans; Keloid; Pain, Postoperative; Treatment Outcome | 2016 |
From genetics to epigenetics: new insights into keloid scarring.
Topics: Animals; Cells, Cultured; Collagen; DNA Methylation; Epigenesis, Genetic; Fibroblasts; Humans; Keloi | 2017 |
Comparative Results in Treatment of Keloids With Intralesional 5-FU/Kenalog, 5-FU/Verapamil, Enalapril Alone,Verapamil Alone, and Laser: A Case Report and Review of the Literature.
Topics: Adult; Drug Therapy, Combination; Enalapril; Fluorouracil; Humans; Injections, Intralesional; Keloid | 2016 |
MicroRNA-29: A Crucial Player in Fibrotic Disease.
Topics: Fibrosis; Gene Expression Regulation; Humans; Keloid; Kidney; Liver Cirrhosis; MicroRNAs; Myocardium | 2017 |
Growing trend of tattooing and its complications in Nigeria.
Topics: Humans; Hypersensitivity; Ink; Keloid; Laser Therapy; Nigeria; Pigmentation Disorders; Skin Diseases | 2017 |
Optimizing Radiotherapy for Keloids: A Meta-Analysis Systematic Review Comparing Recurrence Rates Between Different Radiation Modalities.
Topics: Brachytherapy; Esthetics; Female; Humans; Keloid; Male; Radiotherapy; Radiotherapy Dosage; Recurrenc | 2017 |
Keloid and Hypertrophic Scars Are the Result of Chronic Inflammation in the Reticular Dermis.
Topics: Animals; Cicatrix, Hypertrophic; Dermis; Humans; Interleukins; Keloid | 2017 |
The use of corticosteroids to treat keloids: a review.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Collagen; Fibroblast Grow | 2008 |
Prevention and reduction of scarring in the skin by Transforming Growth Factor beta 3 (TGFbeta3): from laboratory discovery to clinical pharmaceutical.
Topics: Animals; Biocompatible Materials; Cicatrix; Dermis; Drug Design; Humans; Keloid; Mice; Mice, Knockou | 2008 |
Prevention and management of hypertrophic scars and keloids after burns in children.
Topics: Adolescent; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Contracture; Dermatologic Surgic | 2008 |
Postburn sequelae in the pediatric patient: clinical presentations and treatment options.
Topics: Adolescent; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Contracture; Humans; Hypopigment | 2008 |
Antimitotic drug injections and radiotherapy: a review of the effectiveness of treatment for hypertrophic scars and keloids.
Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antimitotic A | 2008 |
Corneal keloid.
Topics: Corneal Diseases; Corneal Surgery, Laser; Humans; Keloid; Keratoplasty, Penetrating; Oculocerebroren | 2008 |
[Efficiency and application safety of Cepan cream. Observation of a new indication].
Topics: Allantoin; Animals; Blepharitis; Burns; Chamomile; Cicatrix; Drug Combinations; Drug Synergism; Eyel | 2008 |
A conjunctival mass in the deep superior fornix after a long retained hard contact lens in a patient with keloids.
Topics: Adrenal Cortex Hormones; Blepharitis; Blepharoptosis; Conjunctival Diseases; Contact Lenses; Device | 2008 |
Hypertrophic scars and keloids--a review of their pathophysiology, risk factors, and therapeutic management.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid; Risk Factors; Wound Healing | 2009 |
Hypertrophic scars and keloids--a review of their pathophysiology, risk factors, and therapeutic management.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid; Risk Factors; Wound Healing | 2009 |
Hypertrophic scars and keloids--a review of their pathophysiology, risk factors, and therapeutic management.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid; Risk Factors; Wound Healing | 2009 |
Hypertrophic scars and keloids--a review of their pathophysiology, risk factors, and therapeutic management.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid; Risk Factors; Wound Healing | 2009 |
A primary care perspective on keloids.
Topics: Humans; Keloid; Physician's Role; Primary Health Care; Wound Healing | 2009 |
Keloid scarring: bench and bedside.
Topics: Adult; Aminoquinolines; Cicatrix; Female; Genetic Predisposition to Disease; Humans; Imiquimod; Immu | 2009 |
Dose-effect relationships for recurrence of keloid and pterygium after surgery and radiotherapy.
Topics: Dose-Response Relationship, Radiation; Humans; Keloid; Linear Models; Pterygium; Recurrence; Relativ | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial Agents; Chr | 2009 |
Genetic susceptibility to raised dermal scarring.
Topics: Cicatrix, Hypertrophic; Genetic Linkage; Genetic Predisposition to Disease; HLA-D Antigens; Humans; | 2009 |
Update on the management of keloids.
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Aminoquinolines; Black or African American; Cryosur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Keloids: current concepts of pathogenesis (review).
Topics: Animals; Cicatrix; Humans; Hypertrophy; Keloid; Wound Healing | 2009 |
[Keloids: pathogenic and therapeutic advances].
Topics: Adrenal Cortex Hormones; Black People; Cryotherapy; Female; Humans; Keloid; Lasers; Male; Radiothera | 2009 |
Laser treatment for scars and wounds.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy | 2009 |
A review of the effectiveness of antimitotic drug injections for hypertrophic scars and keloids.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Bleomycin; Cicatrix, Hypertrophic; Colchicine; Drug Ther | 2009 |
Is radiation therapy for keloids acceptable? The risk of radiation-induced carcinogenesis.
Topics: Humans; Keloid; Neoplasms, Radiation-Induced; Risk Factors | 2009 |
Keloid scarring: new treatments ahead.
Topics: Forecasting; Humans; Keloid | 2009 |
Genetics of keloid scarring.
Topics: Apoptosis; Cicatrix; Clinical Trials as Topic; Genetic Predisposition to Disease; Genome-Wide Associ | 2010 |
The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review.
Topics: Antineoplastic Agents; Bleomycin; Cicatrix; Fluorouracil; Humans; Hypertrophy; Interferon-alpha; Kel | 2010 |
Mechanical receptor-related mechanisms in scar management: a review and hypothesis.
Topics: Animals; Cats; Cicatrix, Hypertrophic; Guinea Pigs; Humans; Keloid; Mechanoreceptors; Nociceptors; O | 2010 |
A radiobiological analysis of multicenter data for postoperative keloid radiotherapy.
Topics: Cobalt Radioisotopes; Combined Modality Therapy; Dose-Response Relationship, Radiation; Ear Diseases | 2011 |
[Therapy of acne scars].
Topics: Acne Vulgaris; Atrophy; Chemexfoliation; Cicatrix; Cicatrix, Hypertrophic; Dermabrasion; Evidence-Ba | 2010 |
Biological agents for controlling excessive scarring.
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Cicatrix, Hypertrophic; Clinical Trials as Topic; | 2010 |
Keloids: a new challenge for nutrition.
Topics: Animals; Diet; Dietary Supplements; Humans; Keloid; Phytotherapy; Stress, Psychological | 2010 |
Scar tissue.
Topics: Adjuvants, Immunologic; Aminoquinolines; Cicatrix, Hypertrophic; Dermabrasion; Esthetics; Glucocorti | 2010 |
Twenty-five years of active laser prevention of scars: what have we learned?
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Lasers, Dye; Low-Level Light Therapy; Surgical Pro | 2010 |
Giant corneal keloid: case report and review of the literature.
Topics: Aged; Blindness; Cornea; Corneal Diseases; Eye Enucleation; Female; Humans; Iris; Keloid; Lens, Crys | 2010 |
Laser treatment of dark skin: an updated review.
Topics: Adult; Cafe-au-Lait Spots; Child; Cicatrix, Hypertrophic; Hair Removal; Hemangioma; Humans; Keloid; | 2010 |
Why don't we have more effective treatment for keloids?
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy | 2010 |
Medical and surgical management of keloids: a review.
Topics: Humans; Keloid; Wound Healing | 2010 |
Role of mitomycin C in reducing keloid recurrence: patient series and literature review.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Ear Auricle; Female; Humans; Keloid; Middle Aged; Mi | 2011 |
[Pseudofolliculitis barbae].
Topics: Benzoyl Peroxide; Black People; Cicatrix; Combined Modality Therapy; Dermatologic Agents; Disease Su | 2010 |
Influence of the human leukocyte antigen complex on the development of cutaneous fibrosis: an immunogenetic perspective.
Topics: Cicatrix, Hypertrophic; Connective Tissue Diseases; Evidence-Based Medicine; Fibrosis; HLA Antigens; | 2010 |
[Management of hypertrophic scars and keloids].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antibiotics, Antineoplastic; Bleomycin; Child; Cicatrix, | 2010 |
Macrophages in skin injury and repair.
Topics: Animals; Antigen Presentation; Cell Proliferation; Cicatrix, Hypertrophic; Extracellular Matrix Prot | 2011 |
Complications of bone-anchored hearing devices.
Topics: Hearing Aids; Hearing Loss, Conductive; Hematoma; Hemorrhage; Humans; Hygiene; Keloid; Necrosis; Pai | 2011 |
Laser scar revision: A review.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy | 2011 |
The evidence for the role of transforming growth factor-beta in the formation of abnormal scarring.
Topics: Biomarkers; Cicatrix; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; Risk Factors; Transformi | 2011 |
Advances in the treatment of keloids.
Topics: Erythema; Humans; Keloid; Patient Education as Topic; Pruritus; Racial Groups; Skin Pigmentation; Ti | 2011 |
Are there any good treatments for keloid scarring after sternotomy?
Topics: Benchmarking; Cicatrix, Hypertrophic; Evidence-Based Medicine; Humans; Keloid; Reoperation; Sternoto | 2011 |
Mechanisms of pathological scarring: role of myofibroblasts and current developments.
Topics: Cicatrix; Cicatrix, Hypertrophic; Granulation Tissue; Humans; Keloid; Liver; Myofibroblasts; Neoplas | 2011 |
Keloids: prevention and management.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antineoplastic Agents; Compression Bandages; Derm | 2011 |
An association between corticosteroid use and melanoma recurrence: a case report and review of the literature.
Topics: Adrenal Cortex Hormones; Aged; Carcinoma in Situ; Carcinoma, Basal Cell; Humans; Keloid; Male; Melan | 2012 |
A review of the role of mechanical forces in cutaneous wound healing.
Topics: Animals; Humans; Keloid; Neovascularization, Physiologic; Skin; Skin Physiological Phenomena; Stress | 2011 |
Circulating fibrocytes--biology and mechanisms in wound healing and scar formation.
Topics: Animals; Biomarkers; Burns; Cell Differentiation; Cicatrix; Cicatrix, Hypertrophic; Connective Tissu | 2011 |
Clinical inquiry: What treatment is best for hypertrophic scars and keloids?
Topics: Cicatrix, Hypertrophic; Cryotherapy; Evidence-Based Medicine; Glucocorticoids; Humans; Injections, I | 2011 |
Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics Part II. Strategies to reduce scar formation after dermatologic procedures.
Topics: Bandages; Cicatrix; Cicatrix, Hypertrophic; Dermatologic Agents; Humans; Keloid; Risk Factors; Skin; | 2012 |
PET scanning in plastic and reconstructive surgery.
Topics: Breast Neoplasms; Diabetic Foot; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Ke | 2012 |
Reconstructing large keloids with neodermis: a systematic review.
Topics: Chondroitin Sulfates; Collagen; Humans; Keloid; Male; Plastic Surgery Procedures; Skin, Artificial; | 2012 |
An overview of biological basis of pathologic scarring.
Topics: Cicatrix; Cytokines; Fibrosis; Humans; Inflammation; Keloid; Skin; Skin Physiological Phenomena; Tra | 2012 |
Genome-wide association study of skin complex diseases.
Topics: Alopecia; Carcinoma, Basal Cell; Dermatitis, Atopic; Female; Genetic Predisposition to Disease; Geno | 2012 |
[Keloid scars of the head and neck].
Topics: Cicatrix; Cicatrix, Hypertrophic; Diagnosis, Differential; Disease Susceptibility; Head; Humans; Kel | 2012 |
A snapshot of gene expression signatures generated using microarray datasets associated with excessive scarring.
Topics: Cicatrix, Hypertrophic; Computational Biology; Gene Expression Profiling; Gene Expression Regulation | 2013 |
Meta-analysis demonstrates association between Arg72Pro polymorphism in the P53 gene and susceptibility to keloids in the Chinese population.
Topics: Amino Acid Substitution; Asian People; Case-Control Studies; Genetic Association Studies; Genetic Pr | 2012 |
[Keloid and hypertrophic scar treatment modalities. An update].
Topics: Adult; Burns; Cell Proliferation; Child; Chondroitin Sulfates; Cicatrix, Hypertrophic; Collagen; Com | 2012 |
[Some aspects of molecular bases of keloid formation].
Topics: Apoptosis; Cytokines; Genetic Predisposition to Disease; Humans; Keloid; Mutation; Polymorphism, Gen | 2011 |
Organ fibrosis inhibited by blocking transforming growth factor-β signaling via peroxisome proliferator-activated receptor γ agonists.
Topics: Epithelial-Mesenchymal Transition; Fibrosis; Humans; Keloid; Kidney; Liver Cirrhosis; Myocardium; PP | 2012 |
Nine-month-old patient with bilateral earlobe keloids.
Topics: Body Piercing; Cryotherapy; Ear, External; Female; Humans; Infant; Keloid | 2013 |
Pulsed dye laser for the treatment of keloid and hypertrophic scars: a systematic review.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Lasers, Dye; Quality of Life; Treatment Outcome | 2012 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
International clinical recommendations on scar management.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Critical Pathways; Evidence-Based Medicine; Human | 2002 |
[Keloids. A fibroproliferative disorder of unknown etiology].
Topics: Cell Division; Fibroblasts; Humans; Keloid; Skin | 2002 |
Optimization of cosmesis in parathyroidectomy.
Topics: Humans; Keloid; Parathyroidectomy | 2002 |
Fibroproliferative scars.
Topics: Cicatrix; Cicatrix, Hypertrophic; Fibrosis; Humans; Keloid; Wound Healing | 2003 |
Hypertrophic scars and keloids: etiology and management.
Topics: Antineoplastic Agents; Cryotherapy; Humans; Interferons; Keloid; Laser Therapy; Occlusive Dressings; | 2003 |
Imiquimod 5% cream for keloid management.
Topics: Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Chemotherapy, Adjuvant; Humans; Im | 2003 |
[SKIN LESIONS FOLLOWING VACCINATIONS].
Topics: BCG Vaccine; Dermatology; Diphtheria Toxoid; Erysipelas; Erythema; Keloid; Mycobacterium bovis; Pert | 1963 |
New therapies for the management of keloids.
Topics: Adrenal Cortex Hormones; Aminoquinolines; Chemotherapy, Adjuvant; Humans; Imiquimod; Immunosuppressi | 2003 |
[The treatment of keloids].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Bandages; Child; Child, Preschool; Clinical | 2003 |
Successful management of viral infections and other dermatoses with imiquimod 5% cream.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aged, 80 and over; Aminoquinolines; Carcinoma in Si | 2003 |
[Keloid and hypertrophic scars].
Topics: Cicatrix, Hypertrophic; Elective Surgical Procedures; Humans; Keloid; Plastic Surgery Procedures; Po | 2003 |
Lymph node involvement in Jorge Lobo's disease: report of two cases.
Topics: Blastomycosis; Diagnosis, Differential; Humans; Keloid; Leg; Lymph Nodes; Male; Middle Aged | 2003 |
Nodular scleroderma: case report and literature review.
Topics: Adult; Hip Joint; Humans; Keloid; Male; Osteoarthritis; Scleroderma, Localized | 2003 |
Elevated vascular endothelial growth factor in keloids: relevance to tissue fibrosis.
Topics: DNA-Binding Proteins; Endothelial Cells; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Hypoxi | 2004 |
Prevention and treatment of excessive dermal scarring.
Topics: Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Clinical Protocols; Humans; Keloid; Terminology as | 2004 |
Turner's syndrome in dermatology.
Topics: Female; Humans; Keloid; Lymphedema; Nevus; Skin Diseases; Skin Neoplasms; Turner Syndrome | 2004 |
Medical and surgical therapies for keloids.
Topics: Adrenal Cortex Hormones; Aminoquinolines; Fluorouracil; Humans; Imiquimod; Injections, Subcutaneous; | 2004 |
Medical and surgical therapies for keloids.
Topics: Adrenal Cortex Hormones; Aminoquinolines; Fluorouracil; Humans; Imiquimod; Injections, Subcutaneous; | 2004 |
Medical and surgical therapies for keloids.
Topics: Adrenal Cortex Hormones; Aminoquinolines; Fluorouracil; Humans; Imiquimod; Injections, Subcutaneous; | 2004 |
Medical and surgical therapies for keloids.
Topics: Adrenal Cortex Hormones; Aminoquinolines; Fluorouracil; Humans; Imiquimod; Injections, Subcutaneous; | 2004 |
Role of adjuvant radiotherapy in recurrent earlobe keloids.
Topics: Chemotherapy, Adjuvant; Dose Fractionation, Radiation; Ear, External; Humans; Keloid; Neoplasms, Rad | 2004 |
[International clinical recommendations on scar management].
Topics: Adrenal Cortex Hormones; Algorithms; Anti-Inflammatory Agents; Bleomycin; Cicatrix; Cicatrix, Hypert | 2004 |
Skin keloid.
Topics: Collagen; Extracellular Matrix; Humans; Incidence; Keloid; Prevalence | 2004 |
Outpatient adolescent surgical problems.
Topics: Adolescent; Ambulatory Surgical Procedures; Body Piercing; Hemorrhoids; Hidradenitis Suppurativa; Hu | 2004 |
Causes of and treatment options for abnormal scar tissue.
Topics: Anti-Inflammatory Agents; Causality; Cicatrix, Hypertrophic; Cryotherapy; Granulation Tissue; Growth | 2005 |
[Keloid and hypertrophic scar].
Topics: Cicatrix, Hypertrophic; Humans; Keloid | 2005 |
Keloid or hypertrophic scar: the controversy: review of the literature.
Topics: Cicatrix, Hypertrophic; Humans; Keloid | 2005 |
Distinct phenotype associated with a cryptic subtelomeric deletion of 19p13.3-pter.
Topics: Abnormalities, Multiple; Adolescent; Chromosome Deletion; Chromosomes, Human, Pair 19; Cleft Palate; | 2005 |
[The impaired healing of the wounds and methods of correction].
Topics: Animals; Cicatrix, Hypertrophic; Ehlers-Danlos Syndrome; Female; Humans; Keloid; Male; Marfan Syndro | 2005 |
Scar management: prevention and treatment strategies.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Humans; Keloid; Laser Therapy; Occlusive Dressings; Radiotherap | 2005 |
Biologically effective doses of postoperative radiotherapy in the prevention of keloids. Dose-effect relationship.
Topics: Brachytherapy; Humans; Keloid; Postoperative Complications; Radiotherapy; Radiotherapy Dosage; Recur | 2005 |
Keloids--clinical diagnosis, pathogenesis, and treatment options.
Topics: Dermatologic Agents; Humans; Keloid; Practice Guidelines as Topic; Practice Patterns, Physicians' | 2004 |
[Therapy for pathologic scars (hypertrophic scars and keloids)].
Topics: Cicatrix, Hypertrophic; Germany; Humans; Keloid; Practice Guidelines as Topic; Practice Patterns, Ph | 2004 |
Keloid pathogenesis and treatment.
Topics: Antimetabolites; Collagen; Combined Modality Therapy; Extracellular Matrix; Fibroblasts; Fluorouraci | 2006 |
Keloid pathogenesis and treatment.
Topics: Antimetabolites; Collagen; Combined Modality Therapy; Extracellular Matrix; Fibroblasts; Fluorouraci | 2006 |
Keloid pathogenesis and treatment.
Topics: Antimetabolites; Collagen; Combined Modality Therapy; Extracellular Matrix; Fibroblasts; Fluorouraci | 2006 |
Keloid pathogenesis and treatment.
Topics: Antimetabolites; Collagen; Combined Modality Therapy; Extracellular Matrix; Fibroblasts; Fluorouraci | 2006 |
Silicon gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2006 |
Silicon gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2006 |
Silicon gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2006 |
Silicon gel sheeting for preventing and treating hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Randomized Controlled Trials as Topic; | 2006 |
[How I treat...fibroproliferative scars].
Topics: Humans; Keloid; Skin; Steroids | 2006 |
Emerging new drugs for scar reduction.
Topics: Antibiotics, Antineoplastic; Bleomycin; Cell Proliferation; Cicatrix, Hypertrophic; Collagen; Cytoki | 2006 |
Case report and summary of literature: giant perineal keloids treated with post-excisional radiotherapy.
Topics: Adult; Female; Humans; Keloid; Perineum; Radiography | 2006 |
A new hypothesis about the origin of uterine fibroids based on gene expression profiling with microarrays.
Topics: Extracellular Matrix; Female; Gene Expression Profiling; Humans; Keloid; Leiomyoma; Oligonucleotide | 2006 |
Epidemiology, aetiology and management of abnormal scarring: a review of the literature.
Topics: Allantoin; Cicatrix, Hypertrophic; Collagen; Cytokines; Humans; Keloid; Tensile Strength | 2006 |
Keloids - a frustrating hurdle in wound healing.
Topics: Combined Modality Therapy; Dermatology; Female; Humans; Keloid; Male; Prognosis; Radiotherapy; Risk | 2004 |
The role of radiation therapy in benign diseases.
Topics: Brachytherapy; Eye Diseases; Graves Ophthalmopathy; Gynecomastia; Histiocytosis, Langerhans-Cell; Hu | 2006 |
[Surgical complications following BCG vaccination].
Topics: Abscess; BCG Vaccine; Humans; Keloid; Lymphadenitis; Osteomyelitis; Risk Factors; Tuberculosis | 2006 |
[Clinical applications of hyaluronic acid].
Topics: Adult; Child; Cicatrix; Humans; Hyaluronic Acid; Keloid; Osteoarthritis; Secondary Prevention; Skin | 2006 |
Keloids and scars: a review of keloids and scars, their pathogenesis, risk factors, and management.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Risk Factors; Signal Transduction; Transforming Growth Facto | 2006 |
The keloid phenomenon: progress toward a solution.
Topics: Animals; Humans; Keloid; Wound Healing | 2007 |
Review of scalp alopecia due to a clinically unapparent or minimally apparent neoplasm (SACUMAN).
Topics: Alopecia; Breast Neoplasms; Carcinoma, Basal Cell; Cicatrix; Hemangiosarcoma; Humans; Keloid; Lympho | 2006 |
[Hyperplastic scars and keloids: part II: Surgical and non-surgical treatment modalities].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Combined Modality Therapy | 2006 |
[Tattooing and piercing in teenagers].
Topics: Adolescent; Adolescent Behavior; Adult; Bacterial Infections; Body Piercing; Child; Dermatitis, Cont | 2006 |
Laser treatment of keloids and hypertrophic scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy; Treatment Outcome | 2007 |
Lobomycosis in Venezuela.
Topics: Blastomycosis; Diagnosis, Differential; Humans; Keloid; Leishmaniasis, Cutaneous; Male; Middle Aged; | 2007 |
Essential role of IL-6 signaling pathway in keloid pathogenesis.
Topics: Animals; Antibodies; Drug Design; Humans; Inflammation Mediators; Interleukin-6; Keloid; Receptors, | 2007 |
Low-dose enalapril in the treatment of surgical cutaneous hypertrophic scar and keloid--two case reports and literature review.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Cicatrix, Hypertrophic; Enalapril; Female; Humans; K | 2006 |
[Therapeutic problems connected with keloid treatment--new treatment possibilities].
Topics: Cicatrix, Hypertrophic; Dermatologic Agents; Fibroblasts; Humans; Keloid; Mitomycin; Scleroderma, Lo | 2006 |
The results of surgical excision and adjuvant irradiation for therapy-resistant keloids: a prospective clinical outcome study.
Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Keloid; Male; Middle Aged; Prospective Studies | 2007 |
Current use of steroids in management of abnormal raised skin scars.
Topics: Cicatrix, Hypertrophic; Collagen; Dexamethasone; Glucocorticoids; Humans; Hydrocortisone; Keloid; Me | 2007 |
Therapy of auricular keloids: review of different treatment modalities and proposal for a therapeutic algorithm.
Topics: Algorithms; Ear; Humans; Keloid | 2007 |
Levels of evidence for the treatment of keloid disease.
Topics: Combined Modality Therapy; Evidence-Based Medicine; Glucocorticoids; Humans; Injections, Intralesion | 2008 |
[Current methods of treatment and prevention of pathologic scars].
Topics: Adrenal Cortex Hormones; Animals; Bandages; Burns; Cicatrix, Hypertrophic; Cryosurgery; Gels; Humans | 2007 |
Transforming growth factor beta (TGFbeta) and keloid disease.
Topics: Collagen; Humans; Keloid; Signal Transduction; Transforming Growth Factor beta; Up-Regulation | 2007 |
[Therapy of keloids].
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Combined Modality Therapy; Cryosurgery; Diagnosis, | 2007 |
A review of the biologic effects, clinical efficacy, and safety of silicone elastomer sheeting for hypertrophic and keloid scar treatment and management.
Topics: Dermatitis, Irritant; Exanthema; Humans; Hypertrophy; Keloid; Occlusive Dressings; Silicone Elastome | 2007 |
Evolution of silicone therapy and mechanism of action in scar management.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Dermatologic Agents; Erythema; Female; Humans; Kelo | 2008 |
Evolution of silicone therapy and mechanism of action in scar management.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Dermatologic Agents; Erythema; Female; Humans; Kelo | 2008 |
Evolution of silicone therapy and mechanism of action in scar management.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Dermatologic Agents; Erythema; Female; Humans; Kelo | 2008 |
Evolution of silicone therapy and mechanism of action in scar management.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Dermatologic Agents; Erythema; Female; Humans; Kelo | 2008 |
Keloids and hypertrophic scars: are they two different sides of the same coin?
Topics: Cicatrix, Hypertrophic; Humans; Keloid | 2008 |
Keloids: pathophysiology and management.
Topics: Adjuvants, Immunologic; Administration, Topical; Animals; Apoptosis; Bandages; Collagen; Cryotherapy | 2007 |
Current progress in keloid research and treatment.
Topics: Humans; Keloid; Research; Wound Healing | 2008 |
Intralesional triamcinolone acetonide for keloid treatment: a systematic review.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide | 2008 |
[Treatment and prevention of the colloid and hypertrophied scars in the region of face and neck].
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Face; Humans; Keloid; Neck; Treatment Outcome | 2008 |
"Operative" use of steroids in head and neck surgery.
Topics: Animals; Cicatrix; Edema; Glucocorticoids; Head; Humans; Keloid; Neck; Pain, Postoperative; Postoper | 1983 |
Cosmetic dermatologic surgery.
Topics: Acne Vulgaris; Alopecia; Chemexfoliation; Cicatrix; Collagen; Dermabrasion; Facial Dermatoses; Femal | 1982 |
[Current problems in the pathology of burns].
Topics: Adult; Bacterial Infections; Bacterial Toxins; Burns; Child; Cicatrix; Granulation Tissue; Humans; H | 1983 |
Scar formation: physiology and pathological states.
Topics: Animals; Cicatrix; Collagen; Contracture; Humans; Inflammation; Joint Diseases; Keloid; Lipid Peroxi | 1984 |
[Diagnosis of skin diseases in Negroes in Africa].
Topics: Black People; Dermatomycoses; Diagnosis, Differential; Humans; Keloid; Leprosy; Skin Diseases; Skin | 1984 |
The therapeutic uses of topical vitamin A acid.
Topics: Acne Vulgaris; Animals; Callosities; Cocarcinogenesis; Fox-Fordyce Disease; Humans; Ichthyosis; Kelo | 1981 |
Disorders of wound healing.
Topics: Cicatrix; Collagen; Humans; Hypertrophy; Keloid; Marfan Syndrome; Metabolic Diseases; Wound Healing; | 1980 |
The biology and control of surface overhealing.
Topics: Burns; Cicatrix; Humans; Keloid; Wound Healing; Wounds and Injuries | 1980 |
Keloids: a review.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Female; Humans; Keloid; Male; Pressure; Skin | 1981 |
Does keloid pathogenesis hold the key to understanding black/white differences in hypertension severity?
Topics: Adolescent; Adult; Aged; Animals; Black People; Cells, Cultured; Cytokines; Female; Humans; Hyperten | 1995 |
Ipsilateral peroneus brevis tendon grafting in a complicated case of traumatic rupture of tibialis anterior tendon.
Topics: Adult; Bicycling; Casts, Surgical; Female; Fibula; Humans; Keloid; Orthotic Devices; Reoperation; Ru | 1995 |
[Treatment of keloids of the earlobe].
Topics: Ear, External; Female; Humans; Keloid; Male; Pressure | 1995 |
Treatment of hypertrophic and keloid scars.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy; Pressure | 1995 |
Superficial x-ray therapy in keloid management: a retrospective study of 24 cases and literature review.
Topics: Combined Modality Therapy; Humans; Keloid; Recurrence; Retrospective Studies; Treatment Outcome | 1995 |
[Surgery and curietherapy of keloids].
Topics: Brachytherapy; Combined Modality Therapy; Humans; Iridium Radioisotopes; Keloid; Postoperative Care | 1995 |
The pathogenesis of hypertrophic/keloid scarring.
Topics: Cicatrix, Hypertrophic; Collagen; Cytokines; Extracellular Matrix; Facial Injuries; Humans; Interleu | 1994 |
Deep fungal infections in the tropics.
Topics: Africa; Chromoblastomycosis; Dermatomycoses; Histoplasmosis; Humans; Keloid; Mycetoma; Paracoccidioi | 1994 |
Cutaneous scars: Part II.
Topics: Burns; Cell Transformation, Neoplastic; Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Skin Disea | 1994 |
Hypertrophic or keloid scars?
Topics: Cicatrix, Hypertrophic; Fibroblasts; Growth Substances; Humans; Keloid; Skin; Wound Healing | 1994 |
Cutaneous scars: Part I.
Topics: Atrophy; Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Skin; Wound Healing | 1994 |
Extra-abdominal desmoid fibromatosis.
Topics: Bone Neoplasms; Diagnosis, Differential; Fibroma; Fibroma, Desmoplastic; Humans; Keloid; Soft Tissue | 1994 |
Earlobe keloids.
Topics: Adrenal Cortex Hormones; Combined Modality Therapy; Ear Deformities, Acquired; Ear, External; Humans | 1994 |
Scars and keloids.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Skin; Wound Healing | 1993 |
Keloids and hypertrophic scars.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Humans; Keloid | 1993 |
Considerations for cosmetic surgery in the black population.
Topics: Black People; Chemexfoliation; Dermabrasion; Hair; Humans; Keloid; Lipectomy; Postoperative Complica | 1993 |
Management of scar contractures, hypertrophic scars, and keloids.
Topics: Cicatrix; Cicatrix, Hypertrophic; Combined Modality Therapy; Contracture; Follow-Up Studies; Humans; | 1995 |
Regulation of elastin synthesis in pathological states.
Topics: Animals; Cutis Laxa; Elastin; Fibrosis; Humans; Keloid; Progeria | 1995 |
Adjunct therapies to surgical management of keloids.
Topics: Combined Modality Therapy; Humans; Keloid; Recurrence; Skin | 1996 |
Pediatric plastic surgery.
Topics: Anesthesia; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Congenital Abnormalities; Facial | 1996 |
Plastic surgery research.
Topics: Cell Transplantation; Cicatrix, Hypertrophic; Computer Simulation; Cytokines; Fetus; Genetic Therapy | 1996 |
[Collagen metabolism in hypertrophic and keloid scars].
Topics: Cicatrix, Hypertrophic; Collagen; Fibroblasts; Humans; Keloid; Wound Healing | 1995 |
Aetiology and management of hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Humans; Keloid | 1996 |
[Pathological scars: what's new?].
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Wound Healing | 1996 |
Cutaneous applications of lasers.
Topics: Aluminum Silicates; Argon; Carbon Dioxide; Cheilitis; Dermabrasion; Equipment Design; Humans; Keloid | 1996 |
Skin disorders in black children.
Topics: Black People; Child; Cicatrix; Hair; Humans; Hypertrophy; Keloid; Nevus, Pigmented; Skin Diseases; S | 1996 |
Plastic and reconstructive surgery of the earlobe.
Topics: Ear Deformities, Acquired; Ear, External; Humans; Keloid; Rhytidoplasty; Surgery, Plastic | 1995 |
Cutaneous and cartilaginous lesions of the auricle.
Topics: Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cysts; Ear Cartilage; Ear Diseas | 1995 |
Laser treatment of hypertrophic scars, keloids, and striae.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy; Pigmentation Disorders; Postoperative Care; P | 1997 |
Hypertrophic scars, keloids, and contractures. The cellular and molecular basis for therapy.
Topics: Adult; Child; Cicatrix, Hypertrophic; Contracture; Cytokines; Female; Fibroblasts; Humans; Interfero | 1997 |
Polypeptide growth factors: targeted delivery systems.
Topics: Animals; Biocompatible Materials; Biomedical Engineering; Bone Morphogenetic Proteins; Cicatrix, Hyp | 1997 |
Treatment of scars: a review.
Topics: Acne Keloid; Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy; Surgery, Plastic | 1997 |
Eosinophilia-myalgia syndrome, eosinophilic fasciitis, and related fibrosing disorders.
Topics: Colonic Diseases; Eosinophilia; Eosinophilia-Myalgia Syndrome; Fasciitis; Fibrosis; Humans; Keloid; | 1997 |
[Soft tissue injuries, burns and scars].
Topics: Adult; Burns; Child; Cicatrix; Facial Injuries; Female; Humans; Keloid; Male; Microsurgery; Soft Tis | 1997 |
Hypertrophic scars and keloids: a recurrent problem revisited.
Topics: Cicatrix; Humans; Hypertrophy; Keloid | 1997 |
The molecular basis of keloid and hypertrophic scar formation.
Topics: Animals; Cicatrix, Hypertrophic; Extracellular Matrix; Fibroblasts; Forecasting; Growth Substances; | 1998 |
Hypertrophic scars and keloids.
Topics: Adrenal Cortex Hormones; Bandages; Burns; Cicatrix, Hypertrophic; Humans; Interferon-gamma; Keloid; | 1998 |
Hypopigmentation along subcutaneous veins following intrakeloid triamcinolone injection: a case report and review of literature.
Topics: Adolescent; Anti-Inflammatory Agents; Burns; Drug Administration Schedule; Female; Follow-Up Studies | 1998 |
[Short- and long-term results of parotidectomy, apropos of 24 cases at the Ougadougou University Hospital Center].
Topics: Adenocarcinoma; Adenoma, Pleomorphic; Adolescent; Adult; Burkina Faso; Cicatrix; Facial Nerve Injuri | 1998 |
[Hypertrophic scar and keloid].
Topics: Cicatrix, Hypertrophic; Cryosurgery; Diagnosis, Differential; Gene Expression; Humans; Keloid; Progn | 1995 |
The treatment of hypertrophic scars and keloids.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Humans; Keloid; | 1998 |
Benign neoplasms of the skin.
Topics: Adult; Child; Diagnosis, Differential; Epidermal Cyst; Family Practice; Hemangioma; Histiocytoma, Be | 1998 |
The molecular and cellular biologic basis for the radiation treatment of benign proliferative diseases.
Topics: Constriction, Pathologic; Humans; Keloid; Macrophages; Monocytes; Peripheral Vascular Diseases; Recu | 1999 |
Keloids and hypertrophic scars: review and treatment strategies.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Combined Modality Therapy; Cryosurgery; Drug Therap | 1999 |
Keloids and hypertrophic scars.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Follow-Up Studies; Humans; Keloid; Recurrence | 1999 |
On the nature of hypertrophic scars and keloids: a review.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid | 1999 |
On the nature of hypertrophic scars and keloids: a review.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid | 1999 |
On the nature of hypertrophic scars and keloids: a review.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid | 1999 |
On the nature of hypertrophic scars and keloids: a review.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid | 1999 |
[Keloids].
Topics: Humans; Keloid; Methods | 1999 |
[Keloid or Hypertrophic scar?].
Topics: Acne Vulgaris; Cicatrix, Hypertrophic; Diagnosis, Differential; Humans; Keloid; Risk Assessment; Wou | 1996 |
A case of giant keloid in the female genitalia.
Topics: Child; Female; Humans; Keloid; Vulva; Vulvar Diseases | 1999 |
Palmar fasciectomy and keloid formation.
Topics: Dupuytren Contracture; Hand; Humans; Keloid; Male; Middle Aged; Recurrence; Reoperation; Skin Transp | 1999 |
The risks of treating keloids with radiotherapy.
Topics: Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Humans; Keloid; Middle Aged; Neop | 1999 |
The body's skin frontier and the challenges of wound healing: keloids.
Topics: Growth Substances; Humans; Keloid; Skin Physiological Phenomena; Wound Healing | 2000 |
Negatively charged static electricity stimulation as a possible mechanism for enhancing the involution of hypertrophic and keloid scars.
Topics: Aged; Cicatrix, Hypertrophic; Clinical Trials as Topic; Electric Stimulation Therapy; Female; Humans | 1999 |
[Radiotherapy of non-malignant diseases: principles and recommendations].
Topics: Arteriovenous Malformations; Dose Fractionation, Radiation; Dupuytren Contracture; Female; Follow-Up | 2000 |
The use of silicone gel sheeting in the management of hypertrophic and keloid scars.
Topics: Bandages; Causality; Cicatrix; Evidence-Based Medicine; Gels; Humans; Hypertrophy; Keloid; Research | 2000 |
Pathophysiology and treatment of fibroproliferative disorders following thermal injury.
Topics: Animals; Burns; Cicatrix, Hypertrophic; Contracture; Humans; Keloid; Wound Healing | 1999 |
Aetiopathogenesis of keloids.
Topics: Age Factors; Collagen; Fibroblasts; Genetic Predisposition to Disease; Humans; Hypersensitivity, Del | 1999 |
Response to tissue injury.
Topics: Adult; Animals; Cicatrix, Hypertrophic; Cytokines; Embryonic and Fetal Development; Humans; Keloid; | 2000 |
Keloids in rural black South Africans. Part 1: general overview and essential fatty acid hypotheses for keloid formation and prevention.
Topics: Arachidonic Acid; Black People; Fatty Acids; Free Radicals; Humans; Keloid; Lipid Peroxidation; Rura | 2000 |
Laser treatment of hypertrophic scars, keloids, and striae.
Topics: Adult; Cicatrix, Hypertrophic; Dose-Response Relationship, Radiation; Humans; Keloid; Laser Therapy; | 2000 |
Cellular signaling in tissue regeneration.
Topics: Animals; Cell Physiological Phenomena; Chemokines; Chronic Disease; Growth Substances; Humans; Keloi | 2000 |
[Silicone as a therapeutic aid in the treatment of hypertrophic scars and keloids].
Topics: Cicatrix; Humans; Hypertrophy; Keloid; Occlusive Dressings; Silicones | 2001 |
New developments in wound care for infants and children.
Topics: Child; Drug Eruptions; Extravasation of Diagnostic and Therapeutic Materials; Humans; Infant; Infant | 2001 |
Hypertrophic scars and keloids.
Topics: Ankle; Cicatrix, Hypertrophic; Foot; Humans; Keloid; Postoperative Complications; Wound Healing | 2001 |
[Advances in the study of etiologic mechanism of keloid].
Topics: Animals; Collagen; Fibroblasts; Humans; Keloid; Receptor, Platelet-Derived Growth Factor alpha; Tran | 2000 |
Scar contractures, hypertrophic scars, and keloids.
Topics: Adrenal Cortex Hormones; Cicatrix; Cicatrix, Hypertrophic; Contracture; Humans; Injections, Intrales | 2001 |
Keloidal scars: a review with a critical look at therapeutic options.
Topics: Cicatrix, Hypertrophic; Cytokines; Diagnosis, Differential; Humans; Keloid; Skin; Transforming Growt | 2002 |
Keloidal scars: a review with a critical look at therapeutic options.
Topics: Cicatrix, Hypertrophic; Cytokines; Diagnosis, Differential; Humans; Keloid; Skin; Transforming Growt | 2002 |
Keloidal scars: a review with a critical look at therapeutic options.
Topics: Cicatrix, Hypertrophic; Cytokines; Diagnosis, Differential; Humans; Keloid; Skin; Transforming Growt | 2002 |
Keloidal scars: a review with a critical look at therapeutic options.
Topics: Cicatrix, Hypertrophic; Cytokines; Diagnosis, Differential; Humans; Keloid; Skin; Transforming Growt | 2002 |
Keloidal scars: a review with a critical look at therapeutic options.
Topics: Cicatrix, Hypertrophic; Cytokines; Diagnosis, Differential; Humans; Keloid; Skin; Transforming Growt | 2002 |
Keloidal scars: a review with a critical look at therapeutic options.
Topics: Cicatrix, Hypertrophic; Cytokines; Diagnosis, Differential; Humans; Keloid; Skin; Transforming Growt | 2002 |
Keloidal scars: a review with a critical look at therapeutic options.
Topics: Cicatrix, Hypertrophic; Cytokines; Diagnosis, Differential; Humans; Keloid; Skin; Transforming Growt | 2002 |
Keloidal scars: a review with a critical look at therapeutic options.
Topics: Cicatrix, Hypertrophic; Cytokines; Diagnosis, Differential; Humans; Keloid; Skin; Transforming Growt | 2002 |
Keloidal scars: a review with a critical look at therapeutic options.
Topics: Cicatrix, Hypertrophic; Cytokines; Diagnosis, Differential; Humans; Keloid; Skin; Transforming Growt | 2002 |
[Indications for radiotherapy of benign lesions: yesterday, today and tomorrow].
Topics: Angioplasty; Coronary Restenosis; Graves Disease; Humans; Intracranial Arteriovenous Malformations; | 2001 |
Scar management: keloid, hypertrophic, atrophic, and acne scars.
Topics: Acne Keloid; Cicatrix; Cicatrix, Hypertrophic; Dermabrasion; Dermatologic Agents; Esthetics; Female; | 2002 |
[Paramount problems in the rehabilitation of severely burned patients].
Topics: Adaptation, Psychological; Adrenergic alpha-Antagonists; Burns; Contracture; Expectorants; Hemodynam | 1975 |
[Indications for surgical treatment of keloids and correlation of various therapeutic methods].
Topics: Adrenal Cortex Hormones; Child; Humans; Keloid; Radiotherapy Dosage; Triamcinolone | 1976 |
[Keloid and hypertrophic scars. Clinical aspects, morphology and treatment].
Topics: Cicatrix; Diagnosis, Differential; Humans; Hypertrophy; Keloid | 1976 |
Keloids: the natural history.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Infant; Keloid; Male; Racial Groups | 1976 |
Would healing: a brief review.
Topics: Cicatrix; Climate; Glucocorticoids; Humans; Humidity; Hypertrophy; Keloid; Oxygen; Partial Pressure; | 1975 |
Skin pigmentation. Current concepts and relevance to plastic surgery.
Topics: Adolescent; Adult; Dermabrasion; Female; Ficusin; Humans; Keloid; Male; Melanins; Melanocyte-Stimula | 1975 |
Topical corticosteroids. Which drug and when?
Topics: Administration, Topical; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Bites and Stings; Burns; | 1992 |
Scar wars strategies. Target collagen.
Topics: Cicatrix, Hypertrophic; Collagen; Humans; Keloid | 1992 |
The microvessels in hypertrophic scars, keloids and related lesions: a review.
Topics: Cicatrix; Humans; Keloid; Microcirculation; Wound Healing | 1992 |
Immunologic associations of keloids.
Topics: Animals; Autoimmunity; Complement System Proteins; Cytokines; Female; Fibroblasts; Growth Substances | 1992 |
[Postoperative sclerosis of the bladder neck: pathogenic mechanisms].
Topics: Adult; Aged; Aged, 80 and over; Animals; Comorbidity; Disease Susceptibility; Dogs; Humans; Iatrogen | 1991 |
[Treatment of keloids].
Topics: Administration, Topical; Adrenal Cortex Hormones; Black People; Brachytherapy; Histocytochemistry; H | 1991 |
Keloids.
Topics: Adult; Age Factors; Diagnosis, Differential; Female; Humans; Keloid; Male; Skin | 1991 |
Management of keloids and hypertrophic scars.
Topics: Cicatrix; Combined Modality Therapy; Foot Diseases; Humans; Hypertrophy; Keloid | 1991 |
In search of the optimal treatment of keloids: report of a series and a review of the literature.
Topics: Humans; Keloid; Meta-Analysis as Topic | 1991 |
Treatment of keloids by 90Sr-90Y beta-rays.
Topics: Adolescent; Adult; Aged; Beta Particles; Child; Combined Modality Therapy; Female; Humans; Keloid; M | 1991 |
Complications of foot surgery. Wound dehiscence, hypertrophic scars, and keloids.
Topics: Cicatrix; Foot; Humans; Hypertrophy; Keloid; Skin; Surgical Wound Dehiscence; Suture Techniques | 1991 |
Keloids: a review of the literature.
Topics: Culture Techniques; Humans; Keloid | 1990 |
Wound healing in the patient with burns.
Topics: Bandages; Burns; Cicatrix; Contracture; Humans; Keloid; Nutritional Physiological Phenomena; Skin Tr | 1990 |
[The mechanism of the formation of pathological scars].
Topics: Cicatrix; Humans; Hypertrophy; Keloid | 1990 |
Scar revision and camouflage.
Topics: Cicatrix; Face; Humans; Injections, Intradermal; Keloid; Surgery, Plastic; Triamcinolone Acetonide | 1990 |
Keloids and hypertrophic scars: a comprehensive review.
Topics: Adrenal Cortex Hormones; Cicatrix; Humans; Hypertrophy; Keloid; Laser Therapy; Pressure; Radiotherap | 1989 |
Keloids and hypertrophic scars: a comprehensive review.
Topics: Adrenal Cortex Hormones; Cicatrix; Humans; Hypertrophy; Keloid; Laser Therapy; Pressure; Radiotherap | 1989 |
Keloids and hypertrophic scars: a comprehensive review.
Topics: Adrenal Cortex Hormones; Cicatrix; Humans; Hypertrophy; Keloid; Laser Therapy; Pressure; Radiotherap | 1989 |
Keloids and hypertrophic scars: a comprehensive review.
Topics: Adrenal Cortex Hormones; Cicatrix; Humans; Hypertrophy; Keloid; Laser Therapy; Pressure; Radiotherap | 1989 |
Pseudofolliculitis barbae.
Topics: Facial Dermatoses; Folliculitis; Hair Removal; Humans; Keloid; Male | 1988 |
Keloids.
Topics: Black People; Humans; Keloid | 1988 |
Perilesional linear atrophy and hypopigmentation after intralesional corticosteroid therapy. Report of two cases and review of the literature.
Topics: Atrophy; Biopsy; Child; Female; Glucocorticoids; Humans; Keloid; Male; Pigmentation Disorders; Skin; | 1988 |
Hypertrophic scars and keloids. Cause and management--current concepts.
Topics: Cicatrix; Humans; Keloid | 1988 |
The problem with scars.
Topics: Bandages; Burns; Cicatrix; Humans; Keloid; Skin Transplantation; Surgical Flaps; Sutures | 1987 |
Postoperative monitoring and treatment.
Topics: Hematoma; Humans; Hypoparathyroidism; Hypothyroidism; Keloid; Monitoring, Physiologic; Postoperative | 1987 |
Keloids: scar revision.
Topics: Adrenal Cortex Hormones; Cryosurgery; Humans; Keloid; Laser Therapy; Lasers; Postoperative Complicat | 1986 |
[Radiation treatment of benign diseases--indications, results and technic].
Topics: Arthritis; Breast Neoplasms; Dupuytren Contracture; Endocrine System Diseases; Eye Diseases; Female; | 1986 |
UCLA conference. Biochemistry of collagen in diseases.
Topics: Collagen; Connective Tissue; Connective Tissue Diseases; Ehlers-Danlos Syndrome; Gene Expression Reg | 1986 |
Sclerosing dermatoses.
Topics: Diagnosis, Differential; Eosinophilia; Fasciitis; Humans; Keloid; Lichen Planus; Radiodermatitis; Sc | 1985 |
Lasers in dermatology: a selective historical review.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatology; Humans; Keloid; Laser Therapy; Melanom | 1985 |
[Side reaction following smallpox vaccination].
Topics: Encephalomyelitis, Acute Disseminated; Exanthema; gamma-Globulins; Humans; Indoles; Keloid; Neoplasm | 1971 |
[Therapy of skin and venereal diseases. Review of the literature of 1967-68].
Topics: Acne Vulgaris; Alopecia; Balanitis; Candidiasis; Dermatitis, Occupational; Dermatomycoses; Diaper Ra | 1969 |
The molecular basis of connective tissue pathology.
Topics: Animals; Basement Membrane; Cattle; Collagen; Connective Tissue; Ehlers-Danlos Syndrome; Elastin; Ep | 1973 |
[Use of corticoids in local treatment of hypertrophic scars and keloids in children].
Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Alanine Transaminase; Black People; Calcium; Child | 1972 |
Hypertrophic scars and keloids. A collective review.
Topics: Age Factors; Cicatrix; Female; Humans; Hypertrophy; Keloid; Male; Pressure; Racial Groups; Skin; Str | 1974 |
Connective tissue responses in Negroes in realtion to disease.
Topics: Adaptation, Biological; Adrenal Cortex Hormones; Africa; Anemia, Sickle Cell; Black People; Bone and | 1974 |
Notes on esthetic surgery in the Indonesian.
Topics: Adult; Asian People; Breast; Chin; Cicatrix; Dermatologic Surgical Procedures; Ear, External; Esthet | 1974 |
[Keloids in the light of modern views and our investigations].
Topics: Humans; Keloid | 1966 |
Trials
168 trials available for khellin and Keloid
| Article | Year |
|---|---|
A Randomized, Double-Blind, Active- and Placebo-Controlled Trial Evaluating a Novel Topical Treatment for Keloid Scars.
Topics: Administration, Topical; Adult; Cicatrix, Hypertrophic; Double-Blind Method; Female; Humans; Keloid; | 2021 |
The effectiveness of long Pulsed Nd:YAG Laser alone for treatment of keloids and hypertrophic scars versus its combination with bleomycin.
Topics: Bleomycin; Cicatrix, Hypertrophic; Humans; Keloid; Lasers, Solid-State; Low-Level Light Therapy; Tre | 2021 |
Efficacy and safety of thermomechanical fractional injury-assisted corticosteroid delivery versus intralesional corticosteroid injection for the treatment of hypertrophic scars: A randomized split-scar trial.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Steroids | 2022 |
Combination of fractional carbon dioxide laser and topical triamcinolone vs intralesional triamcinolone for keloid treatment: A randomised clinical trial.
Topics: Carbon Dioxide; Combined Modality Therapy; Glucocorticoids; Humans; Injections, Intralesional; Keloi | 2022 |
Effect of the combination of photobiomodulation therapy and the intralesional administration of corticoid in the preoperative and postoperative periods of keloid surgery: A randomized, controlled, double-blind trial protocol study.
Topics: Adrenal Cortex Hormones; Adult; Combined Modality Therapy; Double-Blind Method; Female; Humans; Inje | 2022 |
A one-time pneumatic jet-injection of 5-fluorouracil and triamcinolone acetonide for treatment of hypertrophic scars-A blinded randomized controlled trial.
Topics: Cicatrix, Hypertrophic; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intralesional; | 2022 |
Efficacy and safety of the innovative cold atmospheric-pressure plasma technology in the treatment of keloid: A randomized controlled trial.
Topics: Humans; Keloid; Patient Satisfaction; Prospective Studies; Skin; Treatment Outcome | 2022 |
Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Efficacy of a triamcinolone acetonide-loaded dissolving microneedle patch for the treatment of hypertrophic scars and keloids: a randomized, double-blinded, placebo-controlled split-scar study.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Evaluation of botulinum toxin type A for treating post burn hypertrophic scars and keloid in children: An intra-patient randomized controlled study.
Topics: Botulinum Toxins, Type A; Burns; Child; Cicatrix, Hypertrophic; Dermatologic Agents; Humans; Injecti | 2023 |
Intralesional Zinc Hyaluronate Injection to Prevent Keloid Recurrence After Surgical Excision: A Prospective, Randomized Pilot Study.
Topics: Humans; Hyaluronic Acid; Injections, Intralesional; Keloid; Pilot Projects; Prospective Studies; Rec | 2023 |
Comparison of LeniScar Silicone Stick (AnsCare) With Traditional Silicone Gel (Dermatix Ultra) in Wound Scar Prevention and Removal.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Prospective Studies; Silicone Gels; Treatment Outcome | 2023 |
The Clinical Efficacy of Punch Excision Combined With Intralesional Steroid Injection for Keloid Treatment.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Prospective Studies; Steroids; Treatment | 2023 |
Cold anesthesia for pain reduction during intralesional steroid injection for nodulocystic acne.
Topics: Acne Vulgaris; Anesthesia; Humans; Injections, Intralesional; Keloid; Pain; Steroids; Treatment Outc | 2023 |
An Open-Label, Uncontrolled, Single-Arm Clinical Trial of Tofacitinib, an Oral JAK1 and JAK3 Kinase Inhibitor, in Chinese Patients with Keloid.
Topics: Collagen; East Asian People; Humans; Janus Kinase 1; Janus Kinase 3; Keloid; Skin; Treatment Outcome | 2023 |
Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2023 |
Combination therapy using non-ablative fractional laser and intralesional triamcinolone injection for hypertrophic scars and keloids treatment.
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Glucocorticoids; Human | 2019 |
THE USAGE OF RADIOFREQUENCY ABLATION FOR TREATMENT OF KELOIDS AND HYPERTROPHIC SCARS.
Topics: Adult; Catheter Ablation; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Fluorouracil; H | 2019 |
Quantitative assessment of treatment efficacy in keloids using high-frequency ultrasound and shear wave elastography: a preliminary study.
Topics: Adult; Aged; Elastic Modulus; Elasticity Imaging Techniques; Female; Humans; Keloid; Male; Middle Ag | 2020 |
Combined intralesional triamcinolone acetonide and platelet rich plasma versus intralesional triamcinolone acetonide alone in treatment of keloids.
Topics: Humans; Injections, Intralesional; Keloid; Platelet-Rich Plasma; Treatment Outcome; Triamcinolone Ac | 2022 |
Histopathology and immunohistochemical analysis of 5-fluorouracil and triamcinolone treated keloids in double-blinded randomized controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Fluorouracil; Glucocorticoi | 2020 |
Evaluation of Fractional CO
Topics: Carbon Dioxide; Cicatrix, Hypertrophic; Humans; Keloid; Lasers, Gas; Lasers, Solid-State; Treatment | 2020 |
Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.
Topics: Adult; Becaplermin; Chemokine CCL4; Female; Humans; Hyperbaric Oxygenation; Interleukin 1 Receptor A | 2020 |
Benefits of extracorporeal shock waves for keloid treatment: A pilot study.
Topics: Humans; Injections, Intralesional; Keloid; Pilot Projects; Treatment Outcome; Triamcinolone Acetonid | 2020 |
Botulinum toxin type A versus 5-Fluorouracil in treatment of keloid.
Topics: Adolescent; Adult; Botulinum Toxins, Type A; Female; Fluorouracil; Follow-Up Studies; Humans; Hyperp | 2021 |
Cryosurgery as a Single Agent and in Combination with Intralesional Corticosteroids Is Effective on Young, Small Keloids and Induces Characteristic Histological and Immunohistological Changes: A Prospective Randomized Trial.
Topics: Adolescent; Adult; Betamethasone; Combined Modality Therapy; Cryosurgery; Female; Glucocorticoids; H | 2021 |
A comparison of the efficacy of silicone gel containing onion extract and aloe vera to silicone gel sheets to prevent postoperative hypertrophic scars and keloids.
Topics: Aloe; Cicatrix, Hypertrophic; Humans; Keloid; Onions; Plant Extracts; Prospective Studies; Silicone | 2021 |
Botulinum toxin and platelet rich plasma as innovative therapeutic modalities for keloids.
Topics: Humans; Injections, Intralesional; Keloid; Platelet-Rich Plasma; Treatment Outcome; Triamcinolone Ac | 2021 |
Differential responses to folic acid in an established keloid fibroblast cell line are mediated by JAK1/2 and STAT3.
Topics: Cells, Cultured; Fibroblasts; Folic Acid; Glycolysis; Humans; Janus Kinase 1; Janus Kinase 2; Keloid | 2021 |
Strontium-90 brachytherapy following intralesional triamcinolone and 5-fluorouracil injections for keloid treatment: A randomized controlled trial.
Topics: Adult; Brachytherapy; Elastic Modulus; Elasticity Imaging Techniques; Female; Fluorouracil; Humans; | 2021 |
Calcium Electroporation for Keloids: A First-in-Man Phase I Study.
Topics: Adult; Calcium Chloride; Electrochemotherapy; Erythema; Female; Follow-Up Studies; Humans; Keloid; M | 2021 |
A comparison of intralesional verapamil and triamcinolone monotherapy in the treatment of keloids in an African population.
Topics: Glucocorticoids; Humans; Keloid; Prospective Studies; Treatment Outcome; Triamcinolone Acetonide; Ve | 2021 |
Topical cryoanesthesia for the relief of pain caused by steroid injections used to treat hypertrophic scars and keloids.
Topics: Adolescent; Adult; Anesthetics, Local; Cicatrix, Hypertrophic; Cryoanesthesia; Female; Glucocorticoi | 2017 |
Extracorporeal shockwave therapy for treatment of keloid scars.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Biopsy, Needle; Extracorporeal Shockwave Therapy; Female | 2018 |
Intralesional cryotherapy versus excision with corticosteroid injections or brachytherapy for keloid treatment: Randomised controlled trials.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Brachytherapy; Combined Modality Therapy; Cryotherapy; | 2018 |
The efficacy of excision followed by intralesional 5-fluorouracil and triamcinolone acetonide versus excision followed by radiotherapy in the treatment of ear keloids: A randomized control trial.
Topics: Adult; Body Piercing; Combined Modality Therapy; Dermatologic Surgical Procedures; Drug Therapy, Com | 2018 |
Efficacy of Autologous Platelet Concentrates as Adjuvant Therapy to Surgical Excision in the Treatment of Keloid Scars Refractory to Conventional Treatments: A Pilot Prospective Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Transfusion, Autologous; Combined Modality Therapy | 2018 |
Comparison of intralesional verapamil versus intralesional corticosteroids in treatment of keloids and hypertrophic scars: A randomized controlled trial.
Topics: Adolescent; Adult; Calcium Channel Blockers; Cicatrix, Hypertrophic; Factor Analysis, Statistical; F | 2018 |
Efficacy of Botulinum Toxin A in Preventing Recurrence Keloids: Double Blinded Randomized Controlled Trial Study: Intraindividual Subject.
Topics: Adolescent; Adult; Botulinum Toxins, Type A; Female; Follow-Up Studies; Humans; Injections, Intrader | 2017 |
A comparative study of various modalities in the treatment of keloids.
Topics: Adolescent; Adult; Antineoplastic Agents; Calcium Channel Blockers; Combined Modality Therapy; Drug | 2018 |
Hyperbaric oxygen therapy can ameliorate the EMT phenomenon in keloid tissue.
Topics: Adolescent; Adult; Blotting, Western; Cadherins; Epithelial-Mesenchymal Transition; Female; Fibronec | 2018 |
Losartan ointment relieves hypertrophic scars and keloid: A pilot study.
Topics: Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Cicatrix, Hypertrophic; Female; Humans; | 2018 |
Drug-free microneedles in the treatment of keloids: a single-blinded intraindividual controlled clinical trial.
Topics: Complementary Therapies; Female; Humans; Keloid; Male; Needles; Self Care; Single-Blind Method; Tran | 2018 |
Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial.
Topics: Adult; Body Piercing; Burns; Cicatrix, Hypertrophic; Double-Blind Method; Drug Therapy, Combination; | 2019 |
Intralesional triamcinolone alone or in combination with botulinium toxin A is ineffective for the treatment of formed keloid scar: A double blind controlled pilot study.
Topics: Botulinum Toxins, Type A; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; H | 2019 |
Treatment of keloid scars with intralesional triamcinolone and 5-fluorouracil injections - a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Dermatologic Agents; Double-Blind Metho | 2019 |
Efficacy of surgical excision and sub-dermal injection of triamcinolone acetonide for treatment of keloid scars after caesarean section: a single blind randomised controlled trial protocol.
Topics: Adolescent; Adult; Cesarean Section; Combined Modality Therapy; Humans; Injections; Keloid; Middle A | 2019 |
Comparison of the efficacy of intralesional bleomycin versus intralesional triamcinolone acetonide in the treatment of keloids.
Topics: Adult; Antibiotics, Antineoplastic; Bleomycin; Dose-Response Relationship, Drug; Female; Follow-Up S | 2019 |
A useful method to overcome the difficulties of applying silicone gel sheet on irregular surfaces.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Female; Gels; Huma | 2015 |
Comparison of cosmetic outcomes of absorbable versus nonabsorbable sutures in pediatric facial lacerations.
Topics: Absorbable Implants; Adolescent; Bandages; Black or African American; Caregivers; Child; Child, Pres | 2013 |
Generation of site-appropriate tissue by a living cellular sheet in the treatment of mucogingival defects.
Topics: Allografts; Animals; Autografts; Biopsy; Cattle; Cicatrix; Collagen; Color; Epithelial Cells; Esthet | 2014 |
Treatment of keloids and hypertrophic scars with bleomycin and electroporation.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Bleomycin; Cicatrix, Hypertrophic; Electroporation; Female | 2013 |
Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids.
Topics: Adolescent; Adult; Calcium Channel Blockers; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans | 2014 |
Proteomic profiling reveals upregulated protein expression of hsp70 in keloids.
Topics: Adult; Aged; Cells, Cultured; Female; Fibroblasts; Gene Expression Profiling; HSP70 Heat-Shock Prote | 2013 |
Intralesional cryotherapy versus excision and corticosteroids or brachytherapy for keloid treatment: study protocol for a randomised controlled trial.
Topics: Adrenal Cortex Hormones; Brachytherapy; Cicatrix; Clinical Protocols; Cryotherapy; Humans; Injection | 2013 |
Keloids and ultrasound detected fibroids in young African American women.
Topics: Adult; Black or African American; Cicatrix, Hypertrophic; Female; Humans; Keloid; Michigan; Prevalen | 2013 |
A prospective placebo-controlled study on the efficacy of onion extract in silicone derivative gel for the prevention of hypertrophic scar and keloid in median sternotomy wound in pediatric patients.
Topics: Adolescent; Child; Child, Preschool; Cicatrix, Hypertrophic; Double-Blind Method; Female; Humans; In | 2013 |
Adjuvant single-fraction radiotherapy is safe and effective for intractable keloids.
Topics: Adult; Chronic Disease; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Humans; Ke | 2014 |
High-dose-rate brachytherapy for the treatment of recalcitrant keloids: a unique, effective treatment protocol.
Topics: Adolescent; Adult; Aged; Brachytherapy; Clinical Protocols; Female; Follow-Up Studies; Humans; Keloi | 2014 |
A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Argon; Cryosurgery; Elasticity; Female; Gases; Humans; H | 2014 |
Clinical and epidemiological analysis of keloids in Chinese patients.
Topics: Adolescent; Adult; Age Distribution; Age of Onset; Aged; Asian People; Child; Child, Preschool; Chin | 2015 |
Identification of biomarkers involved in differential profiling of hypertrophic and keloid scars versus normal skin.
Topics: Biomarkers; Blotting, Western; Cicatrix, Hypertrophic; Gene Expression Profiling; Humans; Keloid; Re | 2015 |
Intralesional cryotherapy for treatment of keloid scars: a prospective study.
Topics: Adolescent; Adult; Aged; Asian People; Black People; Child; Cryosurgery; Female; Humans; Hypopigment | 2015 |
The treatment of keloids and hypertrophic scars with intralesional bleomycin in skin of color.
Topics: Adolescent; Adult; Bleomycin; Cicatrix, Hypertrophic; Dermatologic Agents; Female; Humans; Injection | 2015 |
Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Botulinum Toxins, Type A; Child; Dermatologic Agents; Do | 2015 |
Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Botulinum Toxins, Type A; Child; Dermatologic Agents; Do | 2015 |
Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Botulinum Toxins, Type A; Child; Dermatologic Agents; Do | 2015 |
Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Botulinum Toxins, Type A; Child; Dermatologic Agents; Do | 2015 |
Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Botulinum Toxins, Type A; Child; Dermatologic Agents; Do | 2015 |
Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Botulinum Toxins, Type A; Child; Dermatologic Agents; Do | 2015 |
Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Botulinum Toxins, Type A; Child; Dermatologic Agents; Do | 2015 |
Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Botulinum Toxins, Type A; Child; Dermatologic Agents; Do | 2015 |
Intralesional botulinum toxin type A equally effective and better tolerated than intralesional steroid in the treatment of keloids: a randomized controlled trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Botulinum Toxins, Type A; Child; Dermatologic Agents; Do | 2015 |
Intralesional triamcinolone alone and in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars.
Topics: Adult; Cicatrix, Hypertrophic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, | 2014 |
Comparison of two devices for the treatment of keloid scars with the use of intralesional cryotherapy: An experimental study.
Topics: Albinism, Oculocutaneous; Argon; Cryotherapy; Freezing; Humans; Hypopigmentation; Keloid; Nitrogen; | 2015 |
Comparison of single intra operative versus an intra operative and two post operative injections of the triamcinolone after wedge excision of keloids of helix.
Topics: Adolescent; Adult; Body Piercing; Dermatologic Surgical Procedures; Ear Auricle; Female; Glucocortic | 2015 |
Ablative CO2 fractional resurfacing in treatment of thermal burn scars: an open-label controlled clinical and histopathological study.
Topics: Adolescent; Adult; Burns; Cicatrix, Hypertrophic; Female; Humans; Keloid; Lasers, Gas; Male; Middle | 2015 |
Effect of triamcinolone in keloids morphological changes and cell apoptosis.
Topics: Adolescent; Adult; Apoptosis; Child; Female; Humans; Injections; Keloid; Longitudinal Studies; Male; | 2015 |
Spray versus intralesional cryotherapy for keloids.
Topics: Administration, Topical; Adolescent; Adult; Aerosols; Aged; Child; Child, Preschool; Cryosurgery; Fe | 2016 |
Treatment of hypertrophic scars and keloids by fractional carbon dioxide laser: a clinical, histological, and immunohistochemical study.
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Collagen; Female; Humans; Immunohistochemistry; Keloid; L | 2016 |
Pulsed dye laser versus long-pulsed Nd:YAG laser in the treatment of hypertrophic scars and keloid: A comparative randomized split-scar trial.
Topics: Cicatrix; Female; Humans; Keloid; Lasers, Dye; Lasers, Solid-State; Low-Level Light Therapy; Male; S | 2016 |
Verapamil is Less Effective than Triamcinolone for Prevention of Keloid Scar Recurrence After Excision in a Randomized Controlled Trial.
Topics: Adolescent; Adult; Cicatrix; Double-Blind Method; Female; Glucocorticoids; Humans; Injections, Intra | 2016 |
The Efficacy of a Silicone Sheet in Postoperative Scar Management.
Topics: Administration, Topical; Adult; Cicatrix, Hypertrophic; Dermatologic Agents; Female; Hallux Valgus; | 2016 |
Therapeutic Efficacy of Intralesional Steroid With Carbon Dioxide Laser Versus With Cryotherapy in Treatment of Keloids: A Randomized Controlled Trial.
Topics: Adult; Combined Modality Therapy; Cryotherapy; Female; Glucocorticoids; Humans; Keloid; Lasers, Gas; | 2016 |
A Randomized, Single-Blind Trial of Clobetasol Propionate 0.05% Cream Under Silicone Dressing Occlusion Versus Intra-Lesional Triamcinolone for Treatment of Keloid.
Topics: Administration, Topical; Adult; Clobetasol; Erythema; Female; Humans; Keloid; Male; Occlusive Dressi | 2017 |
A Topical Anesthetic and Lidocaine Mixture for Pain Relief During Keloid Treatment: A Double-Blind, Randomized Controlled Trial.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Do | 2017 |
An open, randomized, controlled, comparative study of the combined effect of intralesional triamcinolone acetonide and onion extract gel and intralesional triamcinolone acetonide alone in the treatment of hypertrophic scars and keloids.
Topics: Adolescent; Adult; Aged; Cicatrix, Hypertrophic; Drug Therapy, Combination; Female; Gels; Humans; In | 2008 |
Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix, Hypertrophic; Double-Blind Method; Drug | 2009 |
The use of silicone gel in the treatment of fresh surgical scars: a randomized study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cicatrix, Hypertrophic; Female; Humans; Kel | 2009 |
Treatment of keloid scars post-shave excision with imiquimod 5% cream: A prospective, double-blind, placebo-controlled pilot study.
Topics: Adjuvants, Immunologic; Administration, Topical; Adolescent; Adult; Aged; Aminoquinolines; Double-Bl | 2009 |
Effect of camptothecin on collagen synthesis in fibroblasts from patients with keloid.
Topics: Adolescent; Adult; Blotting, Western; Camptothecin; Collagen; DNA Topoisomerases, Type I; Dose-Respo | 2009 |
[Clinical study of auricular keloid treatment with both surgical excision and intralesional injection of low-dose 5-fluorouracil and corticosteroids].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Combined Modality Therapy; Ear, External; Female; Fluoro | 2009 |
Comparison of the effects of short- and long-pulse durations when using a 585-nm pulsed dye laser in the treatment of new surgical scars.
Topics: Adult; Cicatrix; Cicatrix, Hypertrophic; Female; Humans; Keloid; Lasers, Dye; Male; Prospective Stud | 2010 |
Six-month safety results of calcium hydroxylapatite for treatment of nasolabial folds in Fitzpatrick skin types IV to VI.
Topics: Adult; Aged; Biocompatible Materials; Cosmetic Techniques; Dermatologic Agents; Durapatite; Female; | 2009 |
Effects of low-level laser therapy on pain and scar formation after inguinal herniation surgery: a randomized controlled single-blind study.
Topics: Adult; Cicatrix; Hernia, Inguinal; Humans; Keloid; Low-Level Light Therapy; Middle Aged; Pain Measur | 2010 |
Intralesional botulinum toxin type A injection as a new treatment measure for keloids.
Topics: Adolescent; Adult; Apoptosis; Botulinum Toxins, Type A; Cell Proliferation; Drug Administration Sche | 2009 |
Treatment of hypertrophic scars and keloids with an LBO laser (532 nm) and silicone gel sheeting.
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Erythema; Female; Humans; Keloid; Low-Level | 2010 |
A comparative study evaluating the tolerability and efficacy of two topical therapies for the treatment of keloids and hypertrophic scars.
Topics: Administration, Cutaneous; Adult; Cicatrix, Hypertrophic; Dermatologic Agents; Drug Combinations; Fe | 2010 |
Effect of allium cepa-allantoin-pentaglycan gel on skin hypertrophic scars: clinical and video-capillaroscopic results of an open-label, controlled, nonrandomized clinical trial.
Topics: Adult; Allantoin; Cicatrix, Hypertrophic; Drug Therapy, Combination; Female; Gels; Humans; Keloid; M | 2010 |
Surgical excision and immediate postoperative radiotherapy versus cryotherapy and intralesional steroids in the management of keloids: a prospective clinical trial.
Topics: Adolescent; Adult; Cryotherapy; Female; Glucocorticoids; Humans; Injections, Intralesional; Keloid; | 2010 |
Role of mitomycin C in reducing keloid recurrence: patient series and literature review.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Ear Auricle; Female; Humans; Keloid; Middle Aged; Mi | 2011 |
Ear keloids as a primary candidate for the application of mitomycin C after shave excision: in vivo and in vitro study.
Topics: Adolescent; Adult; Body Piercing; Cell Culture Techniques; Ear, External; Female; Fibroblasts; Human | 2011 |
Post-keloidectomy irradiation using high-dose-rate superficial brachytherapy.
Topics: Adolescent; Adult; Aged; Brachytherapy; Dose Fractionation, Radiation; Female; Humans; Keloid; Male; | 2011 |
Pain evaluation and control during and following the treatment of hypertrophic scars and keloids by contact and intralesional cryosurgery--a preliminary study.
Topics: Adult; Cicatrix, Hypertrophic; Cryosurgery; Female; Humans; Keloid; Male; Pain Measurement | 2012 |
Effects of combined intralesional 5-Fluorouracil and topical silicone in prevention of keloids: a double blind randomized clinical trial study.
Topics: Administration, Topical; Adult; Double-Blind Method; Drug Therapy, Combination; Female; Fluorouracil | 2011 |
Comparison of the efficacy of intralesional triamcinolone acetonide and 5-fluorouracil tattooing for the treatment of keloids.
Topics: Administration, Topical; Adult; Double-Blind Method; Fluorouracil; Humans; Injections, Intralesional | 2012 |
The effect of flashlamp pulsed dye laser on the expression of connective tissue growth factor in keloids.
Topics: Adult; Biomarkers; Connective Tissue Growth Factor; Down-Regulation; Female; Humans; Immunohistochem | 2012 |
The treatment of keloids with pneumatic technology: a pilot study.
Topics: Adult; Female; Humans; Hyaluronic Acid; Keloid; Male; Minimally Invasive Surgical Procedures; Pilot | 2012 |
Prosthetic conformer as a pressure device in the prophylactic management of postsurgical auricular keloid formation: a clinical report.
Topics: Adult; Ear Auricle; Ear Deformities, Acquired; Humans; Keloid; Male; Postoperative Complications; Pr | 2013 |
Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments.
Topics: Adrenal Cortex Hormones; Adult; Aged; Biopsy, Needle; Cicatrix, Hypertrophic; Drug Therapy, Combinat | 2002 |
A comparison of the combined effect of cryotherapy and corticosteroid injections versus corticosteroids and cryotherapy alone on keloids: a controlled study.
Topics: Adolescent; Adult; Combined Modality Therapy; Cryotherapy; Female; Glucocorticoids; Humans; Injectio | 2001 |
Evaluation of graded strength glycolic acid (GA) facial peel: an Indian experience.
Topics: Adolescent; Adult; Chemexfoliation; Cohort Studies; Dose-Response Relationship, Drug; Esthetics; Eva | 2003 |
Intralesional 5-fluorouracil as a treatment modality of keloids.
Topics: Adolescent; Adult; Antimetabolites; Child; Fluorouracil; Humans; Keloid; Middle Aged; Prospective St | 2004 |
Modification of a device and its application for intralesional cryosurgery of old recalcitrant keloids.
Topics: Adult; Cryosurgery; Female; Humans; Keloid; Male; Middle Aged; Recurrence; Treatment Outcome | 2004 |
The mystery of the split earlobe.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Body Piercing; Copper; Dermatitis, Contact; Ear, Externa | 2004 |
Treatment of keloids and hypertrophic scars with dermojet injections of bleomycin: a preliminary study.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Bleomycin; Cicatrix, Hypertrophic; Female; Fol | 2005 |
Treatment of hypertrophic scars and keloids with a radiofrequency device: a study of collagen effects.
Topics: Adult; Aged; Biopsy, Needle; Catheter Ablation; Cicatrix, Hypertrophic; Collagen; Equipment Design; | 2005 |
Ineffective treatment of keloids with interferon alpha-2b.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Cell Proliferation; Female; Humans; Interferon alpha-2; | 2006 |
Accumulation of glucose in keloids with FDG-PET.
Topics: Adult; Aged; Female; Fluorodeoxyglucose F18; Glucose; Humans; Keloid; Male; Positron-Emission Tomogr | 2006 |
[Clinical study on keloid treatment with intralesional injection of low concentration 5-fluorouracil].
Topics: Adrenal Cortex Hormones; Adult; Combined Modality Therapy; Female; Fluorouracil; Humans; Hyperplasia | 2006 |
Successful treatment of earlobe keloids with imiquimod after tangential shave excision.
Topics: Administration, Topical; Adolescent; Adult; Aminoquinolines; Antineoplastic Agents; Chemotherapy, Ad | 2006 |
New combination of triamcinolone, 5-Fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars.
Topics: Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorou | 2006 |
Bleomycin tattooing as a promising therapeutic modality in large keloids and hypertrophic scars.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Bleomycin; Chi-Square Dist | 2006 |
Effect of pulse width of a 595-nm flashlamp-pumped pulsed dye laser on the treatment response of keloidal and hypertrophic sternotomy scars.
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Female; Humans; Keloid; Low-Level Light Ther | 2007 |
Effect of pulse width of a 595-nm flashlamp-pumped pulsed dye laser on the treatment response of keloidal and hypertrophic sternotomy scars.
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Female; Humans; Keloid; Low-Level Light Ther | 2007 |
Effect of pulse width of a 595-nm flashlamp-pumped pulsed dye laser on the treatment response of keloidal and hypertrophic sternotomy scars.
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Female; Humans; Keloid; Low-Level Light Ther | 2007 |
Effect of pulse width of a 595-nm flashlamp-pumped pulsed dye laser on the treatment response of keloidal and hypertrophic sternotomy scars.
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Female; Humans; Keloid; Low-Level Light Ther | 2007 |
The results of surgical excision and adjuvant irradiation for therapy-resistant keloids: a prospective clinical outcome study.
Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Keloid; Male; Middle Aged; Prospective Studies | 2007 |
The efficacy of 5% imiquimod cream in the prevention of recurrence of excised keloids.
Topics: Adjuvants, Immunologic; Administration, Topical; Adolescent; Adult; Aminoquinolines; Child; Female; | 2007 |
The effects of onion extract on hypertrophic and keloid scars.
Topics: Administration, Topical; Adult; Allantoin; Cicatrix, Hypertrophic; Drug Combinations; Female; Gels; | 2007 |
Postoperative radiation protocol for keloids and hypertrophic scars: statistical analysis of 370 sites followed for over 18 months.
Topics: Cicatrix, Hypertrophic; Fibroblasts; Follow-Up Studies; Guideline Adherence; Humans; Keloid; Postope | 2007 |
Role of liquid nitrogen alone compared with combination of liquid nitrogen and intralesional triamcinolone acetonide in treatment of small keloids.
Topics: Adult; Anti-Inflammatory Agents; Combined Modality Therapy; Cryosurgery; Female; Humans; Injections, | 2007 |
Effects of interferon-alpha2b on keloid treatment with triamcinolone acetonide intralesional injection.
Topics: Adolescent; Adult; Angiogenesis Inhibitors; Child; Drug Therapy, Combination; Female; Glucocorticoid | 2008 |
Treatment of keloids and hypertrophic scars using bleom.
Topics: Adolescent; Adult; Bleomycin; Child; Cicatrix, Hypertrophic; Cytotoxins; Drug Administration Schedul | 2008 |
[The problem of scars in heart surgery with special reference to the use of static magnetic fields].
Topics: Adult; Cardiac Surgical Procedures; Child; Female; Humans; Keloid; Magnetics; Male; Middle Aged; Ski | 1984 |
Laser treatment of keloids: a clinical trial and an in vitro study with Nd:YAG laser.
Topics: Adult; Cells, Cultured; Clinical Trials as Topic; Collagen; Female; Fibroblasts; Follow-Up Studies; | 1984 |
D-Penicillamine in the treatment of keloids.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Ear, External; Humans; Keloid; | 1981 |
Vitamin E added silicone gel sheets for treatment of hypertrophic scars and keloids.
Topics: Administration, Topical; Adolescent; Adult; Chi-Square Distribution; Cicatrix, Hypertrophic; Drug Th | 1995 |
Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser.
Topics: Adult; Cicatrix, Hypertrophic; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Postoperati | 1995 |
Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser.
Topics: Adult; Cicatrix, Hypertrophic; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Postoperati | 1995 |
Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser.
Topics: Adult; Cicatrix, Hypertrophic; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Postoperati | 1995 |
Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser.
Topics: Adult; Cicatrix, Hypertrophic; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Postoperati | 1995 |
[Treatment of so-called keloid with excision and postoperative electron irradiation].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Combined Modality Therapy; Electrons; Female; Hum | 1995 |
The modified buried vertical mattress suture. A new technique of buried absorbable wound closure associated with excellent cosmesis for wounds under tension.
Topics: Cicatrix, Hypertrophic; Dermatologic Surgical Procedures; Double-Blind Method; Esthetics; Humans; In | 1994 |
A controlled clinical trial of topical silicone gel sheeting in the treatment of hypertrophic scars and keloids.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Gels; Humans; Keloid; Occlusive Dressings; Recurren | 1994 |
[Treatment of keloid by intralesional injections of interferon alfa-2B].
Topics: Adolescent; Adult; Female; Humans; Injections, Intralesional; Interferon alpha-2; Interferon-alpha; | 1993 |
Outcomes of cryosurgery in keloids and hypertrophic scars. A prospective consecutive trial of case series.
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Cryosurgery; Female; Follow-Up Studies; Huma | 1993 |
Topical putrescine (Fibrostat) in treatment of hypertrophic scars: phase II study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Cicatrix, Hypertro | 1996 |
Prevention of earlobe keloid recurrence with postoperative corticosteroid injections versus radiation therapy: a randomized, prospective study and review of the literature.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Chemotherapy, Adjuvant; Combined Modality | 1996 |
Failure of interferon-alpha 2b in the treatment of mature keloids.
Topics: Adolescent; Adult; Female; Humans; Injections, Intralesional; Interferon alpha-2; Interferon-alpha; | 1996 |
A randomized controlled trial of hydrocolloid dressing in the treatment of hypertrophic scars and keloids.
Topics: Adult; Cicatrix, Hypertrophic; Colloids; Female; Humans; Keloid; Lipids; Male; Occlusive Dressings; | 1996 |
Keloid excision and recurrence prophylaxis via intradermal interferon-gamma injections: a pilot study.
Topics: Adolescent; Adult; Antineoplastic Agents; Double-Blind Method; Female; Humans; Injections, Intraderm | 1996 |
Inverse correlation between CD34 expression and proline-4-hydroxylase immunoreactivity on spindle cells noted in hypertrophic scars and keloids.
Topics: Adolescent; Adult; Aged; Antigens, CD34; Child; Child, Preschool; Cicatrix, Hypertrophic; Fluorescen | 1997 |
Static-electric field induction by a silicone cushion for the treatment of hypertrophic and keloid scars.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anions; Child, Preschool; Cicatrix, Hypertrophic; | 1998 |
The use of silicone occlusive sheeting (Sil-K) and silicone occlusive gel (Epiderm) in the prevention of hypertrophic scar formation.
Topics: Adolescent; Adult; Aged; Cicatrix; Female; Gels; Humans; Hypertrophy; Keloid; Laser-Doppler Flowmetr | 1998 |
Treatment of inflamed hypertrophic scars using intralesional 5-FU.
Topics: Acne Vulgaris; Adult; Aged; Anti-Inflammatory Agents; Antimetabolites; Cicatrix; Female; Fluorouraci | 1999 |
Lower limb surgery in Duchenne muscular dystrophy.
Topics: Adolescent; Child; Child, Preschool; Follow-Up Studies; Humans; Keloid; Leg; Muscular Dystrophies; P | 1999 |
Comparison of a silicone gel-filled cushion and silicon gel sheeting for the treatment of hypertrophic or keloid scars.
Topics: Adult; Aged; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; Middle Aged; Silicone Gels | 1999 |
UVA1 for treatment of keloids.
Topics: Adult; Female; Follow-Up Studies; Humans; Keloid; Male; Radiation Dosage; Treatment Outcome; Ultravi | 1999 |
Self-adhesive silicone gel sheet: a treatment for hypertrophic scars and keloids.
Topics: Administration, Topical; Adolescent; Adult; Child; Cicatrix, Hypertrophic; Drug Administration Sched | 2000 |
Effect of the 585 nm flashlamp-pumped pulsed dye laser for the treatment of keloids.
Topics: Adolescent; Adult; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Spectrophotometry | 2001 |
Effect of the 585 nm flashlamp-pumped pulsed dye laser for the treatment of keloids.
Topics: Adolescent; Adult; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Spectrophotometry | 2001 |
Effect of the 585 nm flashlamp-pumped pulsed dye laser for the treatment of keloids.
Topics: Adolescent; Adult; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Spectrophotometry | 2001 |
Effect of the 585 nm flashlamp-pumped pulsed dye laser for the treatment of keloids.
Topics: Adolescent; Adult; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Spectrophotometry | 2001 |
Treatment of keloids by high-dose-rate brachytherapy: A seven-year study.
Topics: Adolescent; Adult; Aged; Brachytherapy; Dose-Response Relationship, Radiation; Female; Humans; Keloi | 2001 |
Prevention of hypertrophic scars and keloids by the prophylactic use of topical silicone gel sheets following a surgical procedure in an office setting.
Topics: Adult; Ambulatory Surgical Procedures; Cicatrix, Hypertrophic; Dermatologic Surgical Procedures; Fem | 2001 |
Silicone versus nonsilicone gel dressings: a controlled trial.
Topics: Adolescent; Adult; Bandages; Child; Child, Preschool; Cicatrix; Cicatrix, Hypertrophic; Female; Huma | 2001 |
The effects of a single dose of 5-fluorouracil on keloid scars: a clinical trial of timed wound irrigation after extralesional excision.
Topics: Adult; Biopsy; Female; Fluorouracil; Humans; Keloid; Male; Pilot Projects; Sodium Chloride; Sutures; | 2001 |
Prevention and treatment of keloids with intralesional verapamil.
Topics: Administration, Topical; Adult; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Inject | 2002 |
Efficacy and safety of intralesional 5-fluorouracil in the treatment of keloids.
Topics: Female; Fluorouracil; Humans; Immunosuppressive Agents; Injections, Intralesional; Keloid; Male; Tre | 2002 |
[Contractubex used in the treatment of postburn scars and keloids].
Topics: Administration, Topical; Allantoin; Bulgaria; Burns, Chemical; Cicatrix, Hypertrophic; Dermatologic | 2001 |
Keloids treated with topical injections of triamcinolone acetonide (kenalog). Immediate and long-term results.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Injections, Int | 1977 |
Some observations on keloids and double control evaluation of intralesional treatment.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Hydrocortisone | 1978 |
Clinical study of a new antikeloid agent.
Topics: Adult; Burns; Clinical Trials as Topic; Double-Blind Method; Glycosides; Humans; Keloid; Placebos; P | 1979 |
In search of the optimal treatment of keloids: report of a series and a review of the literature.
Topics: Humans; Keloid; Meta-Analysis as Topic | 1991 |
Pressure therapy in treatment of hypertrophic scar, burn contracture and keloid: the Kenyan experience.
Topics: Adolescent; Adult; Bandages; Burns; Child; Child, Preschool; Cicatrix; Clothing; Female; Humans; Hyp | 1990 |
Treatment of scars and keloids with a cream containing silicone oil.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix; Female; Humans; Hypertrophy; Infant; Kel | 1990 |
A controlled trial of intralesional recombinant interferon-gamma in the treatment of keloidal scarring. Clinical and histologic findings.
Topics: Adolescent; Adult; Double-Blind Method; Epidermis; Female; Humans; Injections, Intralesional; Interf | 1990 |
Carbon dioxide laser excision of earlobe keloids. A prospective study and critical analysis of existing data.
Topics: Adolescent; Adult; Child; Child, Preschool; Ear Diseases; Ear, External; Follow-Up Studies; Humans; | 1989 |
Applications of laser light of low power density. Experimental and clinical investigations.
Topics: Animals; Cells, Cultured; Clinical Trials as Topic; Double-Blind Method; Fibroblasts; Granulation Ti | 1986 |
[Initial results of high-dosage hyaluromidase long-term therapy ("Hylase" Dessau) in dermatology].
Topics: Clinical Trials as Topic; Humans; Hyaluronoglucosaminidase; Keloid; Scleroderma, Localized; Sclerode | 1972 |
[Bufexamac cream and ointment for the treatment of various dermatoses].
Topics: Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Chronic Disease; Clinical Trials as Topic; | 1973 |
Fluocinolone acetonide 0.2 per cent cream--a co-operative clinical trial.
Topics: Clinical Trials as Topic; Epidermolysis Bullosa; Fluocinolone Acetonide; Folliculitis; Granuloma; Hu | 1968 |
The action of fluocinolone acetonide upon scar tissue formation.
Topics: Biomechanical Phenomena; Cicatrix; Clinical Trials as Topic; Female; Fluocinolone Acetonide; Humans; | 1970 |
Dimethyl sulfoxide (DMSO) in clinical dermatology.
Topics: Amyloidosis; Cicatrix; Clinical Trials as Topic; Dimethyl Sulfoxide; Eczema; Female; Humans; Keloid; | 1966 |
Dimethyl sulfoxide as a vehicle for corticosteroids. A comparison with the occlusive dressing technique.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatitis, Atopic; Dermatitis, Contact; Eczema; F | 1968 |
Other Studies
3176 other studies available for khellin and Keloid
| Article | Year |
|---|---|
vNOTES Lateral Window Approach to Hysterectomy in a Case with Previous History of Multiple Surgeries Resulting in Keloid Scars and Enlarged Uterus with Dense Bladder Adhesions.
Topics: Adult; Cesarean Section; Female; Humans; Hysterectomy; Keloid; Laparoscopy; Natural Orifice Endoscop | 2022 |
The molecular mechanism of GADD153 in apoptosis of keloid fibroblasts exposed to botulinum toxin type A.
Topics: Apoptosis; Botulinum Toxins, Type A; Cell Line; Cells, Cultured; Fibroblasts; Gene Expression; Gene | 2021 |
Exosomes from miR-29a-modified adipose-derived mesenchymal stem cells reduce excessive scar formation by inhibiting TGF-β2/Smad3 signaling.
Topics: Animals; Cell Line; Cicatrix, Hypertrophic; Disease Models, Animal; Down-Regulation; Exosomes; Fibro | 2021 |
LINC00937 suppresses keloid fibroblast proliferation and extracellular matrix deposition by targeting the miR-28-5p/MC1R axis.
Topics: Adolescent; Adult; Cell Proliferation; Cells, Cultured; Extracellular Matrix; Female; Fibroblasts; H | 2021 |
Kindlin-2 promoted the progression of keloids through the Smad pathway and Fas/FasL pathway.
Topics: Adult; Cell Movement; Cell Proliferation; Cells, Cultured; Extracellular Matrix; Fas Ligand Protein; | 2021 |
Genetics and Epigenetics of Keloids.
Topics: DNA Methylation; Epigenesis, Genetic; Epigenomics; Humans; Keloid; Quality of Life | 2022 |
Multi-Antigen Imaging Reveals Inflammatory DC, ADAM17 and Neprilysin as Effectors in Keloid Formation.
Topics: ADAM17 Protein; Adolescent; Adult; Case-Control Studies; Cells, Cultured; Dendritic Cells; Fibroblas | 2021 |
Vitamin D Deficiency and Keloids: Causal Factor or Bystander?
Topics: Humans; Keloid; Vitamin D; Vitamin D Deficiency | 2022 |
Commentary on the Timing of Adjuvant Radiotherapy After Keloid Excision.
Topics: Humans; Keloid; Radiotherapy, Adjuvant; Recurrence | 2021 |
Lack of efficacy of dupilumab in the treatment of keloid disorder.
Topics: Antibodies, Monoclonal, Humanized; Dermatitis, Atopic; Humans; Keloid; Treatment Outcome | 2022 |
Keloid fibroblasts have elevated and dysfunctional mechanotransduction signaling that is independent of TGF-β.
Topics: Actins; Adolescent; Adult; Aged; Cells, Cultured; Female; Fibroblasts; Humans; Keloid; Male; Mechano | 2021 |
Novel treatments for keloid scars.
Topics: Humans; Keloid | 2022 |
Response to 'Lack of efficacy of dupilumab in the treatment of keloid disorder' by MH Tirgan and J Uitto.
Topics: Antibodies, Monoclonal, Humanized; Dermatitis, Atopic; Humans; Keloid | 2022 |
Hyperbaric oxygen treatment on keloid tumor immune gene expression.
Topics: Gene Expression; Humans; Hyperbaric Oxygenation; Keloid; Neoplasms; Oxygen | 2021 |
Commentary on A Neglected Acne Scar Type: Papular Acne Scars and Their Correlations With Keloid Scars.
Topics: Acne Vulgaris; Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid | 2021 |
Botulinum toxin A promotes the transdifferentiation of primary keloid myofibroblasts into adipocyte-like cells.
Topics: Adipocytes; Bone Morphogenetic Protein 4; Botulinum Toxins, Type A; Cell Transdifferentiation; Cells | 2021 |
Invited Discussion on: Adjuvant Radiotherapy for Keloids.
Topics: Combined Modality Therapy; Humans; Keloid; Radiotherapy, Adjuvant; Recurrence | 2022 |
Infected auricular keloid secondary to attempted self-amputation of a gauge earring.
Topics: Amputation, Surgical; Humans; Keloid; Neck; Nose; Otolaryngology; Pharynx | 2021 |
Integrated bioinformatics analysis of core regulatory elements involved in keloid formation.
Topics: Case-Control Studies; Computational Biology; Gene Expression Profiling; Gene Ontology; Genes, Regula | 2021 |
Letter to the Editor: Comment on Jeon HB, et al. Metformin Inhibits Transforming Growth Factor β-Induced Fibrogenic Response of Human Dermal Fibroblasts and Suppresses Fibrosis in Keloid Spheroids ( Ann Plast Surg . 2021;86:406-411).
Topics: Cells, Cultured; Fibroblasts; Fibrosis; Humans; Keloid; Metformin; Transforming Growth Factor beta; | 2022 |
Study on the Mechanism of miR-34a Affecting the Proliferation, Migration, and Invasion of Human Keloid Fibroblasts by Regulating the Expression of SATB1.
Topics: Cell Line, Tumor; Cell Proliferation; Fibroblasts; Humans; Keloid; Matrix Attachment Region Binding | 2021 |
Targeted inhibition of YAP/TAZ alters the biological behaviours of keloid fibroblasts.
Topics: Fibroblasts; Humans; Keloid; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Mot | 2022 |
Tauroursodeoxycholic Acid Decreases Keloid Formation by Reducing Endoplasmic Reticulum Stress as Implicated in the Pathogenesis of Keloid.
Topics: Adult; Animals; Apoptosis; Case-Control Studies; Cholagogues and Choleretics; Endoplasmic Reticulum | 2021 |
Keloids: Does patients' sex influence the presentation and recurrence post-excision?
Topics: Humans; Injections, Intralesional; Keloid; Recurrence; Treatment Outcome | 2022 |
LncRNA HOXA11-AS aggravates the keloid formation by targeting miR-148b-3p/IGFBP5 axis.
Topics: Apoptosis; bcl-2-Associated X Protein; Case-Control Studies; Caspase 3; Cell Movement; Cell Prolifer | 2021 |
Important role of mechanical microenvironment on macrophage dysfunction during keloid pathogenesis.
Topics: Humans; Inflammation; Keloid; Macrophages; Wound Healing | 2022 |
Plasma metabolomic and lipidomic profiling highlights metabolic changes in keloid-prone individuals.
Topics: Humans; Keloid; Lipidomics; Metabolomics | 2022 |
Letter to the Editor: Comment on Jeon HB, et al. Metformin Inhibits Transforming Growth Factor β-Induced Fibrogenic Response of Human Dermal Fibroblasts and Suppresses Fibrosis in Keloid Spheroids ( Ann Plast Surg . 2021;86:406-411).
Topics: Cells, Cultured; Fibroblasts; Fibrosis; Humans; Keloid; Metformin; Transforming Growth Factor beta; | 2022 |
A Methylome and Transcriptome Analysis of Normal Human Scar Cells Reveals a Role for FOXF2 in Scar Maintenance.
Topics: Cicatrix, Hypertrophic; Epigenome; Fibroblasts; Forkhead Transcription Factors; Gene Expression Prof | 2022 |
Is Hypertrophic or Keloid Wound Scar a Risk Factor for Stricture at Esophagogastric Anastomosis Site after Esophageal Cancer Operation?
Topics: Anastomosis, Surgical; Constriction, Pathologic; Esophageal Neoplasms; Esophageal Stenosis; Humans; | 2021 |
Combined laser treatment for ear keloids: Case series: Comparison between two mini-invasive protocols: Comparison between two mini-invasive protocols.
Topics: Combined Modality Therapy; Ear Auricle; Humans; Keloid; Lasers, Gas; Recurrence; Treatment Outcome | 2022 |
Treatment of acne by subcutaneous injection of low-concentration 5-Fluorouracil.
Topics: Acne Vulgaris; Fluorouracil; Humans; Injections, Intralesional; Injections, Subcutaneous; Keloid | 2022 |
Treatment of sebaceous cysts in keloids: Ultrapulse mode-fractionated carbon dioxide lasers combined with injection of low-concentration triamcinolone acetonide and 5-fluorouracil.
Topics: Epidermal Cyst; Fluorouracil; Humans; Injections, Intralesional; Keloid; Lasers, Gas; Treatment Outc | 2022 |
Fully Digital Workflow for Fabrication of A 3D Printed Ear Stent for Auricular Keloids: A Technique Article.
Topics: Combined Modality Therapy; Ear Auricle; Humans; Keloid; Printing, Three-Dimensional; Stents; Workflo | 2022 |
Combination Therapy for a Severe Axillary Keloid with Abscesses: A Case Report.
Topics: Abscess; Adult; Axilla; Child; Female; Humans; Keloid; Middle Aged; Quality of Life; Steroids | 2023 |
Correlation between elastic modulus and clinical severity of pathological scars: a cross-sectional study.
Topics: Adult; Cicatrix, Hypertrophic; Cross-Sectional Studies; Elastic Modulus; Female; Humans; Keloid; Mal | 2021 |
Efficacy and Safety of Contact Cryosurgery in the Treatment of Earlobe Keloids.
Topics: Adolescent; Adult; Child; Cryosurgery; Ear Diseases; Female; Humans; Keloid; Middle Aged; Prospectiv | 2021 |
The increased prevalence of keloids in atopic dermatitis patients with allergic comorbidities: a nationwide retrospective cohort study.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Child; Child, Preschool; Comorbidity; Dermatitis, Ato | 2021 |
Analysis of the expression of FAP-α protein in 2D-keloid fibroblast cultures and in 3D models of keloid.
Topics: Cells, Cultured; Endopeptidases; Fibroblasts; Humans; Keloid; Membrane Proteins | 2022 |
Outcomes of 2-octyl cyanoacrylate skin adhesives following musculoskeletal oncology surgery: A STROBE-compliant observational study.
Topics: Administration, Topical; Adult; Aged; Cyanoacrylates; Female; Hematoma; Humans; Keloid; Male; Middle | 2021 |
[Several problems worthy of attention in non-surgical treatment of scar].
Topics: Attention; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid | 2021 |
[Differences of water barrier function between keloid and its surrounding normal skin in patients with keloids and its related mechanism].
Topics: Adult; China; Cross-Sectional Studies; Female; Humans; Keloid; Male; Middle Aged; Skin; Water; Young | 2022 |
Bioinformatics study on different gene expression profiles of fibroblasts and vascular endothelial cells in keloids.
Topics: Computational Biology; Endothelial Cells; Fibroblasts; Gene Expression Profiling; Gene Ontology; Gen | 2021 |
Long non-coding RNA H19 aggravates keloid progression by upregulating SMAD family member 5 expression via miR-196b-5p.
Topics: Cell Movement; Cell Nucleus; Cell Proliferation; Cell Survival; Cells, Cultured; Cytoplasm; Disease | 2022 |
Clinical status of hospitalized keloid cases from 2013 to 2018.
Topics: Adult; Aged; Asian People; Burns; Cicatrix, Hypertrophic; Female; Hospitalization; Humans; Keloid; M | 2022 |
Long-term explant culture: an improved method for consistently harvesting homogeneous populations of keloid fibroblasts.
Topics: Biomarkers; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Fibroblasts; Gene Expressi | 2022 |
Single-Cell Sequencing Analysis and Weighted Co-Expression Network Analysis Based on Public Databases Identified That TNC Is a Novel Biomarker for Keloid.
Topics: Biomarkers; Cell Differentiation; Datasets as Topic; Fibroblasts; Gene Regulatory Networks; Humans; | 2021 |
Detection and analysis of long noncoding RNA expression profiles related to epithelial-mesenchymal transition in keloids.
Topics: Epithelial-Mesenchymal Transition; Gene Expression Profiling; Humans; Keloid; RNA, Long Noncoding; R | 2022 |
[Gynaecomastia and adipomastia on black skin: Clinical and surgical particularity].
Topics: Adult; Cicatrix, Hypertrophic; Gynecomastia; Humans; Keloid; Male; Retrospective Studies; Skin | 2022 |
Downregulated cytotoxic CD8
Topics: Biomarkers; CD8-Positive T-Lymphocytes; Cicatrix, Hypertrophic; Down-Regulation; Histocompatibility | 2022 |
Identification of Hub Genes of Keloid Fibroblasts by Coexpression Network Analysis and Degree Algorithm.
Topics: Algorithms; Biomarkers; Fibroblasts; Gene Expression Profiling; Homeodomain Proteins; Humans; Keloid | 2022 |
The outcome of postoperative radiation therapy following plastic surgical resection of recurrent ear keloid: a single institution experience.
Topics: Humans; Keloid; Plastics; Prospective Studies; Radiotherapy, Adjuvant; Recurrence; Retrospective Stu | 2022 |
Silencing circular RNAPTPN12 promoted the growth of keloid fibroblasts by activating Wnt signaling pathway via targeting microRNA-21-5p.
Topics: Fibroblasts; Gene Silencing; HEK293 Cells; Humans; Keloid; MicroRNAs; RNA, Circular; Wnt Signaling P | 2022 |
A Facile Strategy for Preparation of Yttrium-90 Therapeutic Sources for Radionuclide Therapy.
Topics: Brachytherapy; Humans; Keloid; Radiometry; Skin Neoplasms; Yttrium Radioisotopes | 2022 |
CircPDE7B/miR-661 axis accelerates the progression of human keloid fibroblasts by upregulating fibroblast growth factor 2 (FGF2).
Topics: Cell Line; Fibroblast Growth Factor 2; Fibroblasts; Humans; Keloid; MicroRNAs; RNA, Circular; Signal | 2022 |
The Polygenic Map of Keloid Fibroblasts Reveals Fibrosis-Associated Gene Alterations in Inflammation and Immune Responses.
Topics: Computational Biology; Disease Susceptibility; Fibroblasts; Fibrosis; Gene Expression Profiling; Gen | 2021 |
An uncommon case of intermenstrual bleeding developing as a side effect of intralesional triamcinolone injection for the treatment of keloids.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Metrorrhagia; Treatment Outcome; Triamci | 2022 |
Integrated Analysis of Single-Cell and Spatial Transcriptomics in Keloids: Highlights on Fibrovascular Interactions in Keloid Pathogenesis.
Topics: Cells, Cultured; Endothelial Cells; Fibroblasts; Humans; Keloid; Skin; Transcriptome | 2022 |
The Efficacy of CT-Based Conformal Electron Beam Radiation Therapy After Keloid Excision.
Topics: Electrons; Humans; Keloid; Recurrence; Retrospective Studies; Tomography, X-Ray Computed; Treatment | 2022 |
Nonresponse and Progression of Diffuse Keloids to Dupilumab Therapy.
Topics: Adolescent; Antibodies, Monoclonal, Humanized; Cytokines; Dermatitis, Atopic; Disease Progression; F | 2022 |
A new combined surgical and medical technique for auricular keloids.
Topics: Combined Modality Therapy; Ear Auricle; Humans; Keloid; Recurrence | 2022 |
Clinical Observation of Subepidermal Vascular Network Flaps in Keloid Patients.
Topics: Animals; Keloid; Skin; Surgical Flaps | 2022 |
Histology and Vascular Architecture Study of Keloid Tissue to Outline the Possible Terminology of Keloid Skin Flaps.
Topics: Humans; Keloid; Skin; Surgical Flaps | 2022 |
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.
Topics: Autoantigens; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Collagen Type I; Fibrobla | 2022 |
CircCOL5A1 inhibits proliferation, migration, invasion, and extracellular matrix production of keloid fibroblasts by regulating the miR-877-5p/EGR1 axis.
Topics: Burns; Cell Movement; Cell Proliferation; Early Growth Response Protein 1; Extracellular Matrix; Fib | 2023 |
Evaluating Symptomatic and Psychosocial Well-being After Keloid Treatment With SCAR-Q.
Topics: Humans; Injections, Intralesional; Keloid; Pain; Pruritus; Treatment Outcome | 2022 |
Optimizing surgical outcome of auricular keloid with a novel multimodal approach.
Topics: Adrenal Cortex Hormones; Adult; Ear Auricle; Female; Humans; Injections, Intralesional; Keloid; Recu | 2022 |
Schwann cells contribute to keloid formation.
Topics: Cicatrix, Hypertrophic; Extracellular Matrix; Humans; Keloid; Schwann Cells; Wound Healing | 2022 |
Risk factors associated with the progression from keloids to severe keloids.
Topics: Case-Control Studies; Humans; Keloid; Quality of Life; Retrospective Studies; Rheumatic Diseases; Ri | 2022 |
Multimodal Imaging and Histopathology Features of a Corneal Keloid.
Topics: Connective Tissue Diseases; Corneal Diseases; Humans; Keloid; Keratoplasty, Penetrating; Multimodal | 2022 |
Tissue chondrification and ossification in keloids with primary report of five cases.
Topics: Cell Differentiation; Cells, Cultured; Chondrogenesis; Collagen; Fibroblasts; Humans; Keloid; Osteog | 2022 |
Exosomes from human adipose-derived mesenchymal stem cells inhibit production of extracellular matrix in keloid fibroblasts via downregulating transforming growth factor-β2 and Notch-1 expression.
Topics: Cell Proliferation; Cells, Cultured; Collagen; Exosomes; Extracellular Matrix; Fibroblasts; Humans; | 2022 |
Sequential therapy with intralesional injections and superficial X-ray therapy in 96 keloids.
Topics: Combined Modality Therapy; Fluorouracil; Humans; Injections, Intralesional; Keloid; Treatment Outcom | 2022 |
Evaluating the efficacy of photodynamic therapy with indocyanine green in the treatment of keloid.
Topics: Humans; Indocyanine Green; Keloid; Lasers, Gas; Photochemotherapy; Pilot Projects; Treatment Outcome | 2022 |
Keloid of earlobe treated with a combination of pneumatic injector device and CO
Topics: Carbon Dioxide; Ear Auricle; Humans; Injections; Keloid; Lasers, Gas; Treatment Outcome | 2022 |
Intralesional vitamin D injection for management of keloids.
Topics: Humans; Injections, Intralesional; Keloid; Treatment Outcome; Vitamin D | 2022 |
Nuclear medicine in the management of superficial skin abnormalities and institutional experience.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Humans; Keloid; Nuclear Medicine; Skin Abnormalities | 2022 |
Quality-of-life of people with keloids and its correlation with clinical severity and demographic profiles.
Topics: Cross-Sectional Studies; Humans; Keloid; Quality of Life; Skin; Wound Healing | 2022 |
Desmoplastic Reaction, Immune Cell Response, and Prognosis in Colorectal Cancer.
Topics: Colorectal Neoplasms; Humans; Keloid; Prognosis; Prospective Studies; Tumor Microenvironment | 2022 |
Secondary Cutaneous Ossification in Keloids of the Lower Abdomen: A Report of Two Cases.
Topics: Abdomen; Endothelial Cells; Humans; Inflammation; Keloid | 2022 |
Krox20 expression in abnormal scars: An immunohistochemical study.
Topics: Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid; Skin; Wound Healing | 2022 |
Quantitative proteomics approach reveals novel biomarkers and pathological mechanism of keloid.
Topics: Biomarkers; Gene Regulatory Networks; Humans; Keloid; Proteins; Proteomics; Skin | 2022 |
TRAF3IP2 regulated by FOXO4 affects fibroblast proliferation, migration, and extracellular matrix deposition in keloid through the TGF-β1/Smad pathway.
Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Cells, | 2022 |
Commentary: Single-Cell Sequencing Analysis and Weighted Co-Expression Network Analysis Based on Public Databases Identified That TNC Is a Novel Biomarker for Keloid.
Topics: Biomarkers; Humans; Keloid; Single-Cell Analysis | 2022 |
The role of altered fatty acid in pathological scars and their dermal fibroblasts.
Topics: Cicatrix, Hypertrophic; Fatty Acids; Fibroblasts; Humans; Inflammation; Keloid; Mechanotransduction, | 2022 |
HOXA11-AS facilitates the proliferation, cell cycle process and migration of keloid fibroblasts through sponging miR-188-5p to regulate VEGFA.
Topics: Animals; Cell Movement; Cell Proliferation; Fibroblasts; Keloid; MicroRNAs; RNA, Long Noncoding; Vas | 2022 |
ETS-related Gene (ERG) is Differentially Expressed in Dermatofibroma (Fibrous Histiocytoma) as Compared With Dermatofibrosarcoma Protuberans and Hypertrophic Scars: A Pilot Immunohistochemical Study.
Topics: Biomarkers, Tumor; Cicatrix, Hypertrophic; Dermatofibrosarcoma; Diagnosis, Differential; Histiocytom | 2022 |
Recurrence of Primary and Secondary Keloids in a Select African American and Afro-Caribbean Population.
Topics: Black or African American; Caribbean Region; Ethnicity; Humans; Keloid; Recurrence; Treatment Outcom | 2022 |
Metabolic reprogramming and Warburg effect in keloids.
Topics: Burns; Humans; Keloid; Skin; Wound Healing | 2022 |
Reply: Metabolic reprogramming and Warburg effect in keloids.
Topics: Burns; Cell Proliferation; Humans; Keloid; Neoplasms | 2022 |
Immunohistochemical expression of Axin-2, as an implication of the role of stem cell in scar pathogenesis and prognosis.
Topics: Axin Protein; Case-Control Studies; Cicatrix, Hypertrophic; Humans; Keloid; Prognosis; Stem Cells | 2022 |
Inhibiting Warburg Effect Can Suppress the Biological Activity and Secretion Function of Keloid Fibroblasts.
Topics: Cell Proliferation; Cells, Cultured; Collagen; Collagen Type I; Cyclin D1; Fibroblasts; Glycogen Syn | 2022 |
Corneal Keloid in Lowe Syndrome.
Topics: Corneal Diseases; Humans; Keloid; Keratoplasty, Penetrating; Oculocerebrorenal Syndrome; Vision Diso | 2022 |
No difference in wound complications with or without a post-operative pressure dressing: Our experience in 135 children undergoing mastoidectomy.
Topics: Bandages; Child; Humans; Keloid; Mastoidectomy; Pain, Postoperative; Retrospective Studies; Surgical | 2022 |
Macrophages of the M1 and M2 types play a role in keloids pathogenesis.
Topics: Humans; Keloid; Macrophages | 2023 |
FBXL6 is dysregulated in keloids and promotes keloid fibroblast growth by inducing c-Myc expression.
Topics: Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Collagen; Cyclin A1; Cyclin D2; Fibrobl | 2023 |
CircSLC8A1 targets miR-181a-5p/HIF1AN pathway to inhibit the growth, migration and extracellular matrix deposition of human keloid fibroblasts.
Topics: Apoptosis; Burns; Cell Proliferation; Extracellular Matrix; Fibroblasts; Humans; Keloid; MicroRNAs; | 2023 |
ASC-J9 Blocks Cell Proliferation and Extracellular Matrix Production of Keloid Fibroblasts through Inhibiting STAT3 Signaling.
Topics: Cell Proliferation; Curcumin; Extracellular Matrix; Fibroblasts; Humans; Interleukin-6; Keloid; Reac | 2022 |
[Treatment of keloids].
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Humans; Keloid | 2022 |
Diagnosis and differential diagnosis of dermatofibrosarcoma protuberans: Utility of high-resolution dynamic contrast-enhanced (DCE) MRI.
Topics: Biomarkers, Tumor; Contrast Media; Dermatofibrosarcoma; Diagnosis, Differential; Histiocytoma, Benig | 2022 |
A Novel Method of Steroid Delivery to Improve the Efficacy of Intralesional Injection in Keloid Treatment.
Topics: Adrenal Cortex Hormones; Humans; Injections, Intralesional; Keloid; Sleep Apnea, Obstructive; Steroi | 2022 |
TSP1 promotes fibroblast proliferation and extracellular matrix deposition via the IL6/JAK2/STAT3 signalling pathway in keloids.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Proliferation; Cells, Cultured; Co | 2022 |
Downregulation of PLK4 expression induces apoptosis and G0/G1-phase cell cycle arrest in keloid fibroblasts.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Down-Regulation; Fibroblasts; G1 Phase Cell C | 2022 |
Development of a Novel Scar Screening System with Machine Learning.
Topics: Algorithms; Cicatrix, Hypertrophic; Humans; Keloid; Machine Learning | 2022 |
The Keloid Area and Severity Index (KASI): an objective tool for the evaluation of keloids.
Topics: Humans; Keloid; Reproducibility of Results | 2022 |
Circular RNA hsa_circ_0057452 facilitates keloid progression by targeting the microRNA-1225-3p/AF4/FMR2 family member 4 axis.
Topics: Cell Proliferation; Family; Gene Expression Regulation, Neoplastic; Humans; Keloid; MicroRNAs; RNA, | 2022 |
Combined analyses of RNA-sequence and Hi-C along with GWAS loci-A novel approach to dissect keloid disorder genetic mechanism.
Topics: Genome-Wide Association Study; Humans; Keloid; MicroRNAs; Polymorphism, Single Nucleotide; RNA, Long | 2022 |
Identification and validation of HOXD3 and UNC5C as molecular signatures in keloid based on weighted gene co-expression network analysis.
Topics: Computational Biology; Gene Expression Regulation; Gene Ontology; Gene Regulatory Networks; Homeodom | 2022 |
Generalized keloids associated with a pituitary tumor.
Topics: Humans; Keloid; Pituitary Neoplasms | 2022 |
Stellate Hypopigmentation in a Pediatric Patient After Treatment with Intralesionally-Injected Corticosteroid.
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Glucocorticoids; Humans; Hypopigmentation; Injecti | 2022 |
Increased expression of bone/cartilage-associated genes and core transcription factors in keloids by RNA sequencing.
Topics: Carboxypeptidases; Cartilage; Collagen; Core Binding Factor Alpha 1 Subunit; Fibroblasts; Gene Expre | 2022 |
Outcomes Associated With Combination Shaving and Cryosurgery Treatment in Patients With Keloid Scars.
Topics: Cicatrix, Hypertrophic; Cryosurgery; Humans; Keloid | 2022 |
Expression of the GZMB Gene Polymorphism, SNP rs8192917, in 990 Han Chinese Patients with Postoperative Keloids.
Topics: Alleles; Case-Control Studies; China; Gene Frequency; Genetic Association Studies; Genetic Predispos | 2022 |
Circular RNA hsa_circ_0043688 serves as a competing endogenous RNA for microRNA-145-5p to promote the progression of Keloids via Fibroblast growth factor-2.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Fibroblast Growth Factor 2; Humans; Keloid; Mic | 2022 |
IL-17 Induces Autophagy Dysfunction to Promote Inflammatory Cell Death and Fibrosis in Keloid Fibroblasts
Topics: Autophagy; Cell Death; Fibroblasts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; | 2022 |
[Research advances on the characteristics of fibroblast in keloid].
Topics: Fibroblasts; Humans; Keloid | 2022 |
Primary Ectopic Breast Carcinoma in Man Mimicking Keloid.
Topics: Adult; Axilla; Breast Neoplasms; Carcinoma, Ductal, Breast; Choristoma; Humans; Keloid; Male; Middle | 2022 |
Older Patients and Patients with Severe Arteriosclerosis Are Less Likely to Develop Keloids and Hypertrophic Scars after Thoracic Midline Incision: A Survey-Based Analysis of 328 Cases.
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Carotid Intima-Media Thickness; Cicatrix, Hypertrophic; C | 2022 |
Microneedle delivery of botulinum toxin type A combined with hyaluronic acid for the synergetic management of multiple sternal keloids with oily skin: A retrospective clinical investigation.
Topics: Adrenal Cortex Hormones; Botulinum Toxins, Type A; Dermatitis, Seborrheic; Humans; Hyaluronic Acid; | 2022 |
Targeting the Akt/PI3K/mTOR signaling pathway for complete eradication of keloid disease by sunitinib.
Topics: Animals; Apoptosis; Cell Proliferation; Fibroblasts; Keloid; Mice; Mice, Nude; Phosphatidylinositol | 2022 |
Relative perfusion index: An objective, quantitative and noninvasive method for evaluating the severity of keloids.
Topics: Cross-Sectional Studies; Humans; Hypoxia; Interleukin-17; Keloid; Pain; Perfusion Index; Pruritus; S | 2022 |
Response: Commentary: Single-Cell Sequencing Analysis and Weighted CoExpression Network Analysis Based on Public Databases Identified That TNC Is a Novel Biomarker for Keloid.
Topics: Biomarkers; Gene Expression Profiling; Gene Regulatory Networks; Humans; Keloid; Single-Cell Analysi | 2022 |
Keloid therapy: A neoteric comparative study.
Topics: Bleomycin; Cicatrix, Hypertrophic; Collagen; Humans; Injections, Intralesional; Keloid; Treatment Ou | 2022 |
Intralesional bleomycin versus intralesional triamcinolone in the treatment of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Humans; Hyperpigmentation; Injections, Intralesional; Keloid; Pai | 2022 |
Identifying miRNAs Associated with the Progression of Keloid through mRNA-miRNA Network Analysis and Validating the Targets of miR-29a-3p in Keloid Fibroblasts.
Topics: Biomarkers; Fibroblasts; Gene Expression Profiling; Humans; Keloid; MicroRNAs; Reproducibility of Re | 2022 |
Circ_0057452 sponges miR-7-5p to promote keloid progression through upregulating GAB1.
Topics: Adaptor Proteins, Signal Transducing; Cell Line, Tumor; Cell Proliferation; Collagen; Gene Expressio | 2022 |
[Is it legitimate to propose surgery of the breast area before the end of puberty?]
Topics: Adolescent; Breast; Female; Humans; Hypertrophy; Keloid; Mammaplasty; Mastectomy; Puberty | 2022 |
Effect of Mortalin on Scar Formation in Human Dermal Fibroblasts and a Rat Incisional Scar Model.
Topics: Animals; Cells, Cultured; Collagen Type I; Fibroblasts; HSP70 Heat-Shock Proteins; Humans; Interleuk | 2022 |
Spontaneous keloids during isotretinoin treatment for acne.
Topics: Acne Vulgaris; Administration, Oral; Dermatologic Agents; Humans; Isotretinoin; Keloid; Treatment Ou | 2022 |
Exosomes released by melanocytes modulate fibroblasts to promote keloid formation: a pilot study.
Topics: Adolescent; Cells, Cultured; Exosomes; Fibroblasts; Humans; Keloid; Melanins; Melanocytes; Pilot Pro | 2022 |
Identification and characterization of four immune-related signatures in keloid.
Topics: CD8-Positive T-Lymphocytes; Humans; Keloid; Macrophages; Signal Transduction; Transcriptome | 2022 |
Topical treatments in the management of keloids and hypertrophic scars: a critically appraised topic.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Humans; Keloid; Skin | 2022 |
Long non-coding RNA HOXA11-AS contributes to the formation of keloid by relieving the inhibition of miR-182-5p on ZNF217.
Topics: Animals; Burns; Cell Proliferation; Down-Regulation; Keloid; Mice; MicroRNAs; RNA, Long Noncoding | 2023 |
Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.
Topics: Cells, Cultured; Endothelial Cells; Fibroblasts; Humans; Keloid; Sequence Analysis, RNA | 2022 |
[Treatment of keloids at the ear].
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Humans; Keloid | 2022 |
The Role of CD28 and CD8
Topics: B7-1 Antigen; CD28 Antigens; CD8-Positive T-Lymphocytes; Flow Cytometry; Humans; Keloid | 2022 |
LncRNA GNAS-AS1 knockdown inhibits keloid cells growth by mediating the miR-188-5p/RUNX2 axis.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromogranins; Core Binding Factor Alpha 1 Subu | 2023 |
Irradiation Methods for Accurate Dose Delivery to Postoperative Keloid Scars With Minimal Normal Tissue Exposure Using TomoTherapy: A Phantom Study.
Topics: Humans; Keloid; Phantoms, Imaging; Photons; Radiometry; Radiotherapy Dosage; Radiotherapy Planning, | 2022 |
Comparative efficacy of intralesional 5 flurouracil and intralesional triamcinolone acetonide in localized plaque psoriasis.
Topics: Drug Therapy, Combination; Fluorouracil; Humans; Hyperpigmentation; Injections, Intralesional; Keloi | 2022 |
Keloids in Darkly Pigmented Skin: Clinical Pattern and Presentation at a Tertiary Health Facility, Southwest Nigeria.
Topics: Adult; Cross-Sectional Studies; Ear, External; Female; Health Facilities; Humans; Keloid; Middle Age | 2022 |
Molecular response of keloids to ionizing radiation: targeting FOXO1 radiosensitizes keloids.
Topics: Apoptosis; Cells, Cultured; Cellular Senescence; Fibroblasts; Forkhead Box Protein O1; Humans; Keloi | 2023 |
Ulvan-Based Nanofibrous Patches Enhance Wound Healing of Skin Trauma Resulting from Cryosurgical Treatment of Keloids.
Topics: Antioxidants; Hemoglobins; Humans; Keloid; Nanofibers; Polyethylene Glycols; Polysaccharides; Skin D | 2022 |
Mast Cells Are Activated in the Giant Earlobe Keloids: A Case Series.
Topics: Cicatrix, Hypertrophic; Collagen; Ear Diseases; Fibroblasts; Humans; Keloid; Mast Cells | 2022 |
Observation of the clinical efficacy of isotope phosphorus-32 dressing combined with diprospan and mucopolysaccharide polysulphate cream in the treatment of keloids.
Topics: Bandages; Emollients; Humans; Keloid; Treatment Outcome | 2022 |
An improved explants culture method: Sustainable isolation of keloid fibroblasts with primary characteristics.
Topics: Cell Movement; Cell Proliferation; Cells, Cultured; Extracellular Matrix; Fibroblasts; Humans; Keloi | 2022 |
[Clinical effects of pulsed dye laser dynamically combined with triamcinolone acetonide in the treatment of keloids].
Topics: Female; Humans; Keloid; Lasers, Dye; Male; Quality of Life; Retrospective Studies; Treatment Outcome | 2022 |
Skin fibrosis associated with keloid, scleroderma and Jorge Lobo's disease (lacaziosis): An immuno-histochemical study.
Topics: Endothelial Cells; Fibroblasts; Fibrosis; Forkhead Transcription Factors; Humans; Keloid; Ki-67 Anti | 2022 |
Assessment of intralesional injection of botulinum toxin type A in hypertrophic scars and keloids: Clinical and pathological study.
Topics: Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Collagen; Humans; Injections, Intralesional; Keloi | 2022 |
Two Cases of Insulin-Derived Amyloidosis With Acanthosis Nigricans-Like Changes.
Topics: Acanthosis Nigricans; Amyloidosis; Amyloidosis, Familial; Humans; Insulin; Keloid | 2022 |
Surgical excision and skin grafting combined with intralesional injection of triamcinolone for the treatment of keloids after syndactyly release.
Topics: Humans; Injections, Intralesional; Keloid; Retrospective Studies; Skin Transplantation; Treatment Ou | 2023 |
Initial experience with brachytherapy treatment adjuvant to surgical resection of keloid scars in the pediatric population.
Topics: Adolescent; Brachytherapy; Child; Humans; Keloid; Recurrence; Retrospective Studies; Treatment Outco | 2022 |
Brocq's geometric phagedena over penis with keloidal scars.
Topics: Humans; Keloid; Male; Penis; Pyoderma Gangrenosum; Ulcer | 2022 |
Endothelial-mesenchymal transition as a novel mechanism for generating myofibroblasts during wound healing and scarring.
Topics: Animals; Cicatrix, Hypertrophic; Factor VII; Humans; Keloid; Mice; Myofibroblasts; Wound Healing | 2023 |
Landscape of circulating metabolic fingerprinting for keloid.
Topics: Humans; Keloid; Logistic Models; Palmitoylcarnitine; Phosphorylcholine; Sphingosine | 2022 |
Trauma-induced Adult Xanthogranuloma Mimicking Keloid on the Left Nasal Ala.
Topics: Adult; Humans; Keloid; Nose; Skin Neoplasms | 2023 |
Invariant chain of the MAIT-TCR vα7.2-Jα33 as a novel diagnostic biomarker for keloids.
Topics: Biomarkers; Cicatrix, Hypertrophic; Humans; Keloid; Receptors, Antigen, T-Cell | 2023 |
The Inhibition of Adipose-Derived Stem Cells on the Invasion of Keloid Fibroblasts.
Topics: Cells, Cultured; Fibroblasts; Humans; Keloid; Skin; Stem Cells | 2022 |
Skin endothelial cell and microcirculation function study in recurred keloids patients after keloid surgery and radiotherapy.
Topics: Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Keloid; Microcirculation; Skin | 2022 |
The Sphingolipids Metabolism Mechanism and Associated Molecular Biomarker Investigation in Keloid.
Topics: Biomarkers; Fibroblasts; Humans; Keloid; Signal Transduction; Sphingolipids | 2023 |
Early outcomes of complete excision followed by immediate postoperative single fractional 10 Gy for anterior chest keloids: A preliminary results.
Topics: Humans; Keloid; Postoperative Period; Treatment Outcome | 2023 |
The transcriptional profile of keloidal Schwann cells.
Topics: Gene Expression Profiling; Humans; Keloid; Schwann Cells; Skin; Wound Healing | 2022 |
The deubiquitinating enzyme USP37 promotes keloid fibroblasts proliferation and collagen production by regulating the c-Myc expression.
Topics: Cell Proliferation; Collagen; Deubiquitinating Enzymes; Endopeptidases; Fibroblasts; Humans; Keloid; | 2023 |
The Role of Hippo Signaling Pathway and ILK in the Pathophysiology of Human Hypertrophic Scars and Keloids: An Immunohistochemical Investigation.
Topics: Cicatrix, Hypertrophic; DNA-Binding Proteins; Hippo Signaling Pathway; Humans; Keloid; Muscle Protei | 2022 |
tRNA derived fragment tsRNA-14783 promotes M2 polarization of macrophages in keloid.
Topics: Humans; Keloid; Macrophages; Phosphatidylinositol 3-Kinases; RNA, Transfer; Wnt Signaling Pathway | 2022 |
Keloidal dermatofibroma: Clinicopathological comparison of 52 cases with a series of 2077 other dermatofibromas.
Topics: Collagen; Histiocytoma, Benign Fibrous; Humans; Keloid; Skin; Skin Neoplasms | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Cryotherapy; Humans; Injections, Intralesional; Keloid; Pain; Prospective S | 2023 |
hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Topics: Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs; Skin Neoplasms; T-Box Domain Proteins | 2023 |
hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Topics: Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs; Skin Neoplasms; T-Box Domain Proteins | 2023 |
hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Topics: Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs; Skin Neoplasms; T-Box Domain Proteins | 2023 |
hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Topics: Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs; Skin Neoplasms; T-Box Domain Proteins | 2023 |
hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Topics: Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs; Skin Neoplasms; T-Box Domain Proteins | 2023 |
hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Topics: Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs; Skin Neoplasms; T-Box Domain Proteins | 2023 |
hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Topics: Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs; Skin Neoplasms; T-Box Domain Proteins | 2023 |
hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Topics: Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs; Skin Neoplasms; T-Box Domain Proteins | 2023 |
hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940.
Topics: Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs; Skin Neoplasms; T-Box Domain Proteins | 2023 |
A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy.
Topics: Humans; Keloid; Nomograms; Radiotherapy, Adjuvant; Recurrence; Thorax; Treatment Outcome | 2023 |
A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy.
Topics: Humans; Keloid; Nomograms; Radiotherapy, Adjuvant; Recurrence; Thorax; Treatment Outcome | 2023 |
A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy.
Topics: Humans; Keloid; Nomograms; Radiotherapy, Adjuvant; Recurrence; Thorax; Treatment Outcome | 2023 |
A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy.
Topics: Humans; Keloid; Nomograms; Radiotherapy, Adjuvant; Recurrence; Thorax; Treatment Outcome | 2023 |
A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy.
Topics: Humans; Keloid; Nomograms; Radiotherapy, Adjuvant; Recurrence; Thorax; Treatment Outcome | 2023 |
A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy.
Topics: Humans; Keloid; Nomograms; Radiotherapy, Adjuvant; Recurrence; Thorax; Treatment Outcome | 2023 |
A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy.
Topics: Humans; Keloid; Nomograms; Radiotherapy, Adjuvant; Recurrence; Thorax; Treatment Outcome | 2023 |
A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy.
Topics: Humans; Keloid; Nomograms; Radiotherapy, Adjuvant; Recurrence; Thorax; Treatment Outcome | 2023 |
A Nomogram with the Keloid Activity Assessment Scale for Predicting the Recurrence of Chest Keloid after Surgery and Radiotherapy.
Topics: Humans; Keloid; Nomograms; Radiotherapy, Adjuvant; Recurrence; Thorax; Treatment Outcome | 2023 |
Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy.
Topics: Adult; Female; Humans; Keloid; Male; Prognosis; Radiotherapy, Adjuvant; Recurrence | 2022 |
Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy.
Topics: Adult; Female; Humans; Keloid; Male; Prognosis; Radiotherapy, Adjuvant; Recurrence | 2022 |
Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy.
Topics: Adult; Female; Humans; Keloid; Male; Prognosis; Radiotherapy, Adjuvant; Recurrence | 2022 |
Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy.
Topics: Adult; Female; Humans; Keloid; Male; Prognosis; Radiotherapy, Adjuvant; Recurrence | 2022 |
Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy.
Topics: Adult; Female; Humans; Keloid; Male; Prognosis; Radiotherapy, Adjuvant; Recurrence | 2022 |
Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy.
Topics: Adult; Female; Humans; Keloid; Male; Prognosis; Radiotherapy, Adjuvant; Recurrence | 2022 |
Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy.
Topics: Adult; Female; Humans; Keloid; Male; Prognosis; Radiotherapy, Adjuvant; Recurrence | 2022 |
Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy.
Topics: Adult; Female; Humans; Keloid; Male; Prognosis; Radiotherapy, Adjuvant; Recurrence | 2022 |
Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy.
Topics: Adult; Female; Humans; Keloid; Male; Prognosis; Radiotherapy, Adjuvant; Recurrence | 2022 |
The Combination of the Mini-Punch Technique and Photodynamic Therapy for the Treatment of Mandibular Keloids and Hypertrophic Scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Photochemotherapy | 2022 |
The Combination of the Mini-Punch Technique and Photodynamic Therapy for the Treatment of Mandibular Keloids and Hypertrophic Scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Photochemotherapy | 2022 |
The Combination of the Mini-Punch Technique and Photodynamic Therapy for the Treatment of Mandibular Keloids and Hypertrophic Scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Photochemotherapy | 2022 |
The Combination of the Mini-Punch Technique and Photodynamic Therapy for the Treatment of Mandibular Keloids and Hypertrophic Scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Photochemotherapy | 2022 |
sQuiz your knowledge! A strange keloid on the ear
Topics: Humans; Keloid | 2022 |
sQuiz your knowledge! A strange keloid on the ear
Topics: Humans; Keloid | 2022 |
sQuiz your knowledge! A strange keloid on the ear
Topics: Humans; Keloid | 2022 |
sQuiz your knowledge! A strange keloid on the ear
Topics: Humans; Keloid | 2022 |
Acne Scars: An Update on Management
Topics: Acne Vulgaris; Atrophy; Humans; Keloid; Quality of Life; Treatment Outcome; Wound Healing | 2022 |
Acne Scars: An Update on Management
Topics: Acne Vulgaris; Atrophy; Humans; Keloid; Quality of Life; Treatment Outcome; Wound Healing | 2022 |
Acne Scars: An Update on Management
Topics: Acne Vulgaris; Atrophy; Humans; Keloid; Quality of Life; Treatment Outcome; Wound Healing | 2022 |
Acne Scars: An Update on Management
Topics: Acne Vulgaris; Atrophy; Humans; Keloid; Quality of Life; Treatment Outcome; Wound Healing | 2022 |
[Morphogenetic and pathogenetic features of hypertrophic and keloid scars of the head and neck].
Topics: Adolescent; Adult; Aged; Cicatrix, Hypertrophic; Collagen; Humans; Keloid; Matrix Metalloproteinase | 2022 |
[Morphogenetic and pathogenetic features of hypertrophic and keloid scars of the head and neck].
Topics: Adolescent; Adult; Aged; Cicatrix, Hypertrophic; Collagen; Humans; Keloid; Matrix Metalloproteinase | 2022 |
[Morphogenetic and pathogenetic features of hypertrophic and keloid scars of the head and neck].
Topics: Adolescent; Adult; Aged; Cicatrix, Hypertrophic; Collagen; Humans; Keloid; Matrix Metalloproteinase | 2022 |
[Morphogenetic and pathogenetic features of hypertrophic and keloid scars of the head and neck].
Topics: Adolescent; Adult; Aged; Cicatrix, Hypertrophic; Collagen; Humans; Keloid; Matrix Metalloproteinase | 2022 |
CTHRC1+ fibroblasts are stimulated by macrophage-secreted SPP1 to induce excessive collagen deposition in keloids.
Topics: Collagen; Extracellular Matrix Proteins; Fibroblasts; Humans; Keloid; Macrophages; Osteopontin | 2022 |
CTHRC1+ fibroblasts are stimulated by macrophage-secreted SPP1 to induce excessive collagen deposition in keloids.
Topics: Collagen; Extracellular Matrix Proteins; Fibroblasts; Humans; Keloid; Macrophages; Osteopontin | 2022 |
CTHRC1+ fibroblasts are stimulated by macrophage-secreted SPP1 to induce excessive collagen deposition in keloids.
Topics: Collagen; Extracellular Matrix Proteins; Fibroblasts; Humans; Keloid; Macrophages; Osteopontin | 2022 |
CTHRC1+ fibroblasts are stimulated by macrophage-secreted SPP1 to induce excessive collagen deposition in keloids.
Topics: Collagen; Extracellular Matrix Proteins; Fibroblasts; Humans; Keloid; Macrophages; Osteopontin | 2022 |
Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors.
Topics: Humans; Keloid; Neoplasms; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Rubber; Tu | 2023 |
Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors.
Topics: Humans; Keloid; Neoplasms; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Rubber; Tu | 2023 |
Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors.
Topics: Humans; Keloid; Neoplasms; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Rubber; Tu | 2023 |
Double enhancement effect of a surface dose with tungsten rubber bolus in photon radiotherapy for keloids and superficial tumors.
Topics: Humans; Keloid; Neoplasms; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Rubber; Tu | 2023 |
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies.
Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Keloid; Mice; Quality of | 2022 |
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies.
Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Keloid; Mice; Quality of | 2022 |
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies.
Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Keloid; Mice; Quality of | 2022 |
Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies.
Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Keloid; Mice; Quality of | 2022 |
Bioinformatics analysis and identification of dysregulated POSTN in the pathogenesis of keloid.
Topics: Calcium-Binding Proteins; Cell Adhesion Molecules; Cell Movement; Collagen; Computational Biology; H | 2023 |
Bioinformatics analysis and identification of dysregulated POSTN in the pathogenesis of keloid.
Topics: Calcium-Binding Proteins; Cell Adhesion Molecules; Cell Movement; Collagen; Computational Biology; H | 2023 |
Bioinformatics analysis and identification of dysregulated POSTN in the pathogenesis of keloid.
Topics: Calcium-Binding Proteins; Cell Adhesion Molecules; Cell Movement; Collagen; Computational Biology; H | 2023 |
Bioinformatics analysis and identification of dysregulated POSTN in the pathogenesis of keloid.
Topics: Calcium-Binding Proteins; Cell Adhesion Molecules; Cell Movement; Collagen; Computational Biology; H | 2023 |
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Topics: Cell Proliferation; Exosomes; Fibroblasts; Humans; Keloid; MicroRNAs; Plasma; RNA, Circular; Skin; S | 2022 |
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Topics: Cell Proliferation; Exosomes; Fibroblasts; Humans; Keloid; MicroRNAs; Plasma; RNA, Circular; Skin; S | 2022 |
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Topics: Cell Proliferation; Exosomes; Fibroblasts; Humans; Keloid; MicroRNAs; Plasma; RNA, Circular; Skin; S | 2022 |
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Topics: Cell Proliferation; Exosomes; Fibroblasts; Humans; Keloid; MicroRNAs; Plasma; RNA, Circular; Skin; S | 2022 |
Atopic dermatitis is associated with an increased risk of keloids: A case-control study.
Topics: Case-Control Studies; Dermatitis, Atopic; Eczema; Hand Dermatoses; Humans; Keloid | 2023 |
Atopic dermatitis is associated with an increased risk of keloids: A case-control study.
Topics: Case-Control Studies; Dermatitis, Atopic; Eczema; Hand Dermatoses; Humans; Keloid | 2023 |
Atopic dermatitis is associated with an increased risk of keloids: A case-control study.
Topics: Case-Control Studies; Dermatitis, Atopic; Eczema; Hand Dermatoses; Humans; Keloid | 2023 |
Atopic dermatitis is associated with an increased risk of keloids: A case-control study.
Topics: Case-Control Studies; Dermatitis, Atopic; Eczema; Hand Dermatoses; Humans; Keloid | 2023 |
Keloids and Hypertrophic Scars.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Humans; Keloid; Paresthesia; Quality of Life | 2022 |
PI3K/AKT pathway promotes keloid fibroblasts proliferation by enhancing glycolysis under hypoxia.
Topics: Cell Proliferation; Fibroblasts; Glucose; Glycolysis; Humans; Hypoxia; Hypoxia-Inducible Factor 1, a | 2023 |
Contour first-retrospective study of an algorithmic approach of auricular keloids.
Topics: Ear Auricle; Ear, External; Fluorouracil; Humans; Keloid; Recurrence; Retrospective Studies; Treatme | 2023 |
Is the UVA1 phototherapy an effective option in keloids treatment?
Topics: Humans; Keloid; Phototherapy; Treatment Outcome; Ultraviolet Therapy | 2023 |
Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank.
Topics: Biological Specimen Banks; Cicatrix, Hypertrophic; Cohort Studies; Cross-Sectional Studies; Dermatit | 2023 |
EGR1/NOX4 pathway regulates oxidative stress and further facilitates fibrosis progression in keloids responses to TGF-β1.
Topics: Early Growth Response Protein 1; Fibroblasts; Humans; Keloid; NADPH Oxidase 4; Oxidative Stress; Rea | 2022 |
Prevalence, exposure and the public knowledge of keloids on four continents.
Topics: Adult; Cross-Sectional Studies; Female; Ghana; Humans; Keloid; Male; Middle Aged; Prevalence; Reprod | 2023 |
LncRNA-ZNF252P-AS1/miR-15b-5p promotes the proliferation of keloid fibroblast by regulating the BTF3-STAT3 signaling pathway.
Topics: Animals; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Cyclin D1; Fibrob | 2022 |
SPARC promotes fibroblast proliferation, migration, and collagen production in keloids by inactivation of p53.
Topics: Cell Proliferation; Cells, Cultured; Collagen; Fibroblasts; Humans; Keloid; Osteonectin; Tumor Suppr | 2023 |
Congenital glaucoma as a presenting feature of Rubinstein-Taybi syndrome in an infant with a novel pathogenic variant in the
Topics: CREB-Binding Protein; Frameshift Mutation; Glaucoma; Humans; Hydrophthalmos; Infant; Keloid; Male; M | 2023 |
Risk single-nucleotide polymorphism-mediated enhancer-promoter interaction drives keloids through long noncoding RNA down expressed in keloids.
Topics: Fibroblasts; Genome-Wide Association Study; Humans; Keloid; Polymorphism, Single Nucleotide; Promote | 2023 |
Down expressed in keloid (DEIK): a new player in the pathogenesis of keloids.
Topics: Cells, Cultured; Fibroblasts; Humans; Keloid | 2023 |
Greater understanding about genetic factors in keloid development.
Topics: Humans; Keloid | 2023 |
Common Dermatologic Conditions in Skin of Color.
Topics: Acne Keloid; Humans; Hyperpigmentation; Keloid; Quality of Life; Skin Pigmentation | 2023 |
Cyclical Stretching Induces Excess Intracellular Ca2+ Influx in Human Keloid-Derived Fibroblasts In Vitro.
Topics: Calcium; Cells, Cultured; Fibroblasts; Humans; Keloid; Skin | 2023 |
Integration of single-cell and bulk transcriptomics reveals immune-related signatures in keloid.
Topics: Drug Delivery Systems; Endothelial Cells; Gene Expression Profiling; Humans; Keloid; Transcriptome | 2023 |
TWEAK/Fn14 signaling may function as a reactive compensatory mechanism against extracellular matrix accumulation in keloid fibroblasts.
Topics: Collagen; Extracellular Matrix; Fibroblasts; Humans; Keloid; Signal Transduction | 2023 |
Relief of Extracellular Matrix Deposition Repression by Downregulation of IRF1-Mediated TWEAK/Fn14 Signaling in Keloids.
Topics: Cytokine TWEAK; Down-Regulation; Extracellular Matrix; Humans; Interferon Regulatory Factor-1; Keloi | 2023 |
Keloid scar after herpes zoster ophthalmicus.
Topics: Antiviral Agents; Herpes Zoster Ophthalmicus; Humans; Keloid | 2023 |
Mechanisms underlying pathological scarring by fibroblasts during wound healing.
Topics: Extracellular Matrix; Fibroblasts; Humans; Keloid; Quality of Life; Wound Healing | 2023 |
Targeting the Glycolytic Enzyme PGK1 to Inhibit the Warburg Effect: A New Strategy for Keloid Therapy.
Topics: Cell Proliferation; Fibroblasts; Glucose Transporter Type 1; Glycolysis; Humans; Hypoxia; Keloid; La | 2023 |
Influence of Transforming Growth Factors beta 1 and beta 3 in the Scar Formation Process.
Topics: Cicatrix, Hypertrophic; Fibroblasts; Humans; Hypertrophy; Keloid; Transforming Growth Factor beta; T | 2023 |
Giant acquired digital fibrokeratoma.
Topics: Fingers; Humans; Keloid; Keratosis; Skin Neoplasms | 2023 |
IncRNA MIAT Accelerates Keloid Formation by miR-411-5p/JAG1 Axis.
Topics: Cell Proliferation; Humans; Jagged-1 Protein; Keloid; MicroRNAs; Myocardial Infarction; RNA, Long No | 2023 |
Risk factors associated with keloid infections: A five-year retrospective study.
Topics: Adult; Humans; Keloid; Quality of Life; Recurrence; Retrospective Studies; Risk Factors | 2023 |
IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation.
Topics: Animals; Down-Regulation; Extracellular Matrix; Fibroblasts; Humans; Janus Kinases; Keloid; Mice; Ne | 2023 |
A clinimetric assessment of the validity and reliability of 3D technology for scar surface area measurement.
Topics: Burns; Cicatrix; Cicatrix, Hypertrophic; Correlation of Data; Humans; Keloid; Observer Variation; Re | 2023 |
A Pellino-2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium-digital keloid dysplasia.
Topics: Humans; Inflammasomes; Keloid; NLR Family, Pyrin Domain-Containing 3 Protein; Pterygium; Ubiquitin-P | 2023 |
Laparoscopic procedures-induced keloids: A retrospective case series study.
Topics: Female; Humans; Keloid; Laparoscopy; Male; Retrospective Studies; Skin | 2023 |
| Frequency of Keloid and Hypertrophic Scar in Post-cardiac Surgery Wounds.
Topics: Cardiac Surgical Procedures; Cicatrix, Hypertrophic; Heart; Humans; Keloid | 2023 |
[Status of diagnosis and treatment of hypertrophic scar and keloid].
Topics: Cicatrix, Hypertrophic; Humans; Hyperplasia; Inflammation; Keloid; Risk Factors | 2023 |
Questions raised by a case of adult-onset linear nodular scleroderma.
Topics: Adult; Female; Humans; Hydroxychloroquine; Keloid; Scleroderma, Localized; Scleroderma, Systemic; Sk | 2022 |
Oleanolic acid regulates the proliferation and extracellular matrix of keloid fibroblasts by mediating the TGF-β1/SMAD signaling pathway.
Topics: Cell Proliferation; Cells, Cultured; Extracellular Matrix; Fibroblasts; Humans; Keloid; Matrix Metal | 2023 |
Microtoxin for Improving Pore Size, Skin Laxity, Sebum Control, and Scars: A Roundtable on Integrating Intradermal Botulinum Toxin Type A Microdoses Into Clinical Practice.
Topics: Botulinum Toxins, Type A; Humans; Injections, Intradermal; Keloid; Sebum; Skin | 2023 |
Laser Combined with Radiotherapy for Keloid Treatment: A Novel and Efficient Comprehensive Therapy with a Lower Recurrence Rate.
Topics: Humans; Keloid; Laser Therapy; Lasers, Gas; Recurrence; Retrospective Studies; Treatment Outcome | 2023 |
Skin of Color Representation in Clinical Trials: An Analysis of Clinicaltrials.gov From 2008-2022.
Topics: Clinical Trials as Topic; Dermatitis, Seborrheic; Humans; Keloid; Skin; Skin Pigmentation | 2023 |
Validation of HDR brachytherapy doses in the treatment of keloid scars using the egs_brachy Monte Carlo application.
Topics: Brachytherapy; Computer Simulation; Humans; Keloid; Monte Carlo Method; Phantoms, Imaging; Radiometr | 2023 |
Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model.
Topics: Computational Biology; Databases, Factual; Gene Expression Profiling; Humans; Keloid; Skin | 2023 |
Retrospective study of keloid formation after CO
Topics: Carbon Dioxide; Hidradenitis Suppurativa; Humans; Keloid; Retrospective Studies | 2023 |
SUMOylation mediates the disassembly of the Smad4 nuclear export complex via RanGAP1 in KELOIDS.
Topics: Active Transport, Cell Nucleus; Cell Nucleus; GTPase-Activating Proteins; Humans; Keloid; Smad4 Prot | 2023 |
Epidemiological and clinical features of paediatric inpatients for scars: A retrospective study.
Topics: Adult; Aged; Burns; Child; Cross-Sectional Studies; Female; Humans; Inpatients; Keloid; Lower Extrem | 2023 |
Circ_0008450 regulates keloid-derived fibroblast proliferation, migration, invasion and apoptosis with increased IGFBP5 through sponging miR-1224-5p.
Topics: Apoptosis; Burns; Cell Proliferation; Humans; Insulin-Like Growth Factor Binding Protein 5; Keloid; | 2023 |
Chest Wall Keloids Depicted by 18 F-Piflufolastat PET/CT Imaging.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Male; Neoplasm Recurrence, Local; Positron Emission Tomograp | 2023 |
Effectiveness of various methods of manual scar therapy.
Topics: Cicatrix; Cicatrix, Hypertrophic; Complementary Therapies; Cupping Therapy; Dry Needling; Humans; Ke | 2023 |
PTB Regulates the Metabolic Pathways and Cell Function of Keloid Fibroblasts through Alternative Splicing of PKM.
Topics: Alternative Splicing; Cell Communication; Cell Proliferation; Fibroblasts; Glycolysis; Humans; Keloi | 2023 |
Postsurgical hypertrophic scars after nonmelanoma skin cancer surgical excision: clinical and confocal microscopy outcomes of topical 5-fluorouracil in an adjuvant setting.
Topics: Adjuvants, Immunologic; Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Microscopy, Confocal; | 2023 |
Osteomodulin contributes to keloid development by regulating p38 MAPK signaling.
Topics: Cell Proliferation; Cells, Cultured; Extracellular Matrix Proteins; Fibroblasts; Humans; Keloid; p38 | 2023 |
Dasatinib Attenuates Fibrosis in Keloids by Decreasing Senescent Cell Burden.
Topics: Animals; Cells, Cultured; Cellular Senescence; Dasatinib; Fibroblasts; Keloid; Mice; Procollagen | 2023 |
Adipose-derived mesenchymal stem cells-sourced exosomal microRNA-7846-3p suppresses proliferation and pro-angiogenic role of keloid fibroblasts by suppressing neuropilin 2.
Topics: Cell Proliferation; Endothelial Cells; Fibroblasts; Hedgehog Proteins; Humans; Keloid; Mesenchymal S | 2023 |
Comprehensive treatment of ear keloid: A case report.
Topics: Adult; Combined Modality Therapy; Ear Auricle; Female; Humans; Injections, Intralesional; Keloid; Re | 2023 |
Keloids, hypertrophic scars, and uterine fibroid development: a prospective ultrasound study of Black and African American women.
Topics: Adult; Black or African American; Cicatrix, Hypertrophic; Cohort Studies; Female; Humans; Keloid; Le | 2023 |
Mapping variation of extracellular matrix in human keloid scar by label-free multiphoton imaging and machine learning.
Topics: Collagen; Diagnostic Imaging; Extracellular Matrix; Humans; Keloid; Machine Learning | 2023 |
Intralesional Triamcinolone Acetonide Injection of Keloid Resulting in Copious Purulence.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone Acetoni | 2023 |
Keloid Core Factor CTRP3 Overexpression Significantly Controlled TGF-
Topics: Cell Proliferation; Cells, Cultured; Fibroblasts; Humans; Keloid; RNA, Small Interfering; Transformi | 2023 |
Benefits of Reducing Incision Tension in Hard-To-Close Keloid Surgery.
Topics: Humans; Keloid; Skin; Surgical Wound | 2023 |
Surgical Treatment for Chest "Lock" Keloid Using Autologous Split-Thickness Skin Grafting and Postoperative Radiotherapy.
Topics: Humans; Keloid; Recurrence; Skin Transplantation; Thorax; Treatment Outcome | 2023 |
Surgical Core Excision With Tongue Flap Closure in Combination With Electron Beam Radiotherapy in the Treatment of Ear Keloids.
Topics: Adult; Electrons; Etoposide; Humans; Keloid; Plastic Surgery Procedures; Retrospective Studies; Trea | 2023 |
Phyllodes tumour initially diagnosed as keloid.
Topics: Breast; Breast Neoplasms; Female; Humans; Keloid; Mastectomy; Phyllodes Tumor | 2023 |
Trauma-induced Adult Xanthogranuloma Mimicking Keloid on the Left Nasal Ala.
Topics: Adult; Humans; Keloid; Nose; Skin Neoplasms | 2023 |
Evidence of inter- and intra-keloid heterogeneity through analysis of dermal fibroblasts: A new insight in deciphering keloid physiopathology.
Topics: Cells, Cultured; Collagen; Dermis; Fibroblasts; Humans; Keloid; Skin | 2023 |
Revealing the roles of glycosphingolipid metabolism pathway in the development of keloid: a conjoint analysis of single-cell and machine learning.
Topics: Cell Differentiation; Collagen; Humans; Inflammation; Keloid; Lipid Metabolism; Sulfatases | 2023 |
Enhancement of Zyxin Promotes Skin Fibrosis by Regulating FAK/PI3K/AKT and TGF-β Signaling Pathways via Integrins.
Topics: Animals; Fibroblasts; Fibrosis; Humans; Integrins; Keloid; Mice; Phosphatidylinositol 3-Kinases; Pro | 2023 |
Topical Anesthetic versus Lidocaine Mixture for Pain Relief During Keloid Treatment: A Prospective, Split Study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Female; Hum | 2023 |
5-ALA-PDT induced ferroptosis in keloid fibroblasts via ROS, accompanied by downregulation of xCT, GPX4.
Topics: Aminolevulinic Acid; Down-Regulation; Ferroptosis; Fibroblasts; Humans; Keloid; Photochemotherapy; P | 2023 |
UCHL1 aggravates skin fibrosis through an IGF-1-induced Akt/mTOR/HIF-1α pathway in keloid.
Topics: Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblasts; Humans; Insulin-Like Growth Facto | 2023 |
Rare Complication of Massive Depigmentation After Postoperative Treatment of Giant Keloid Combined With Strontium-90.
Topics: Acne Vulgaris; Adolescent; Humans; Keloid; Postoperative Period; Recurrence; Strontium Radioisotopes | 2023 |
Deciphering the single-cell transcriptome network in keloids with intra-lesional injection of triamcinolone acetonide combined with 5-fluorouracil.
Topics: Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intralesional; Keloid; Transcriptome; T | 2023 |
Role and mechanism of Circ-PDE7B in the formation of keloid.
Topics: Apoptosis; Bandages; Cell Proliferation; Cyclic Nucleotide Phosphodiesterases, Type 7; Down-Regulati | 2023 |
IGFBP-7 secreted by adipose-derived stem cells inhibits keloid formation via the BRAF/MEK/ERK signaling pathway.
Topics: Cell Proliferation; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans | 2023 |
Keloid scars: Are funding criteria driving health inequalities in plastic surgery?
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Plastic Surgery Procedures; Surgery, Plastic | 2023 |
Therapy of pathological scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Lasers; Wound Healing | 2023 |
The combined application of bleomycin and triamcinolone for the treatment of keloids and hypertrophic scars: An effective therapy for treating refractory keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Retrospective Studies; | 2023 |
Glycoprotein M6A upregulation detected by transcriptome analysis controls the proliferation of keloidal fibroblasts.
Topics: Cell Proliferation; Cicatrix, Hypertrophic; Fibroblasts; Gene Expression Profiling; Glycoproteins; H | 2023 |
Current Practice in Keloid Treatment: a Survey of Dutch Dermatologists and Plastic Surgeons.
Topics: Adrenal Cortex Hormones; Dermatologists; Humans; Keloid; Surgeons; Surveys and Questionnaires; Treat | 2023 |
Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation.
Topics: Combined Modality Therapy; Humans; Keloid; Neoplasm Recurrence, Local; Prospective Studies; Recurren | 2023 |
Preliminary clinical observations on autologous cultured skin fibroblasts transplantation in the treatment of keloids: a case report.
Topics: Cells, Cultured; Fibroblasts; Humans; Keloid; Skin; Transplantation, Autologous | 2023 |
Hsa_circ_0000129 knockdown attenuates proliferation and migration in keloid fibroblasts by targeting miR-485-3p/SGMS2 pathway.
Topics: Burns; Cell Proliferation; Fibroblasts; Humans; Keloid; MicroRNAs | 2023 |
Modified Fitzpatrick Scale-Skin Color and Reactivity.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Skin; Skin Diseases; Skin Pigmentation | 2023 |
Anti-Fibrotic Effects of RF Electric Currents.
Topics: Cicatrix, Hypertrophic; Extracellular Matrix Proteins; Fibroblasts; Humans; Keloid; Matrix Metallopr | 2023 |
Rare case of corneal keloid following radial keratotomy for myopia.
Topics: Adult; Connective Tissue Diseases; Corneal Diseases; Eye Injuries; Humans; Keloid; Keratotomy, Radia | 2023 |
Successful Treatment of a Keloid With Surgical Excision Followed by Pentoxifylline, Intralesional Corticosteroid, and Intralesional 5-Fluorouracil.
Topics: Adrenal Cortex Hormones; Fluorouracil; Humans; Injections, Intralesional; Keloid; Pentoxifylline; Tr | 2023 |
Vitamin D in Keloids: An alternative to steroids?
Topics: Humans; Keloid; Steroids; Vitamin D; Vitamins | 2023 |
The Role of Radiation Therapy in Adult and Pediatric Keloid Management: A National Survey of Radiation Oncologists.
Topics: Adult; Child; Humans; Keloid; Neoplasms, Radiation-Induced; Physicians; Radiation Oncologists | 2023 |
Establishment of a humanized mouse model of keloid diseases following the migration of patient immune cells to the lesion: Patient-derived keloid xenograft (PDKX) model.
Topics: Animals; Disease Models, Animal; Fibroblasts; Heterografts; Humans; Keloid; Mice; Mice, Inbred NOD; | 2023 |
Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue.
Topics: Cells, Cultured; Fibroblasts; Humans; Keloid; Proteins | 2023 |
Quantitative study on dose distribution of Freiburg flap for keloid high-dose-rate brachytherapy based on MatriXX.
Topics: Brachytherapy; Gamma Rays; Humans; Keloid; Phantoms, Imaging; Software | 2023 |
Autocrine IL-6 drives cell and extracellular matrix anisotropy in scar fibroblasts.
Topics: Anisotropy; Cells, Cultured; Extracellular Matrix; Fibroblasts; Humans; Interleukin-6; Keloid | 2023 |
[Keloid nomogram prediction model based on weighted gene co-expression network analysis and machine learning].
Topics: Algorithms; Calibration; Humans; Keloid; Machine Learning; Nomograms | 2023 |
miR-15a-5p up-regulates TLR4 and induces the formation of hypertrophic scars and keloids.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cicatrix, Hypertrophic; Keloid; Mice; Mice, Nude; Mic | 2023 |
Safety and efficacy of intralesional injection of enalapril versus triamcinolone acetonide in the treatment of keloids.
Topics: Cicatrix, Hypertrophic; Enalapril; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonid | 2023 |
Silibinin Downregulates Types I and III Collagen Expression via Suppression of the mTOR Signaling Pathway.
Topics: Animals; Collagen; Collagen Type I; Humans; Keloid; Mammals; Signal Transduction; Silybin; TOR Serin | 2023 |
The tunneling technique of intralesional 5-fluorouracil in combination with triamcinolone injection for intractable keloids.
Topics: Fluorouracil; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone; Triamcino | 2023 |
Nodular (keloidal) scleroderma.
Topics: Humans; Keloid; Scleroderma, Localized; Scleroderma, Systemic | 2023 |
Metformin ointment may relieve hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Hypertrophy; Keloid; Ointments | 2023 |
Pemphigus vulgaris complicated with extensive keloid formation and induction of keloid regression during disease recurrence.
Topics: Humans; Keloid; Pemphigus; Recurrence | 2023 |
Risk factors for recurrence after keloid surgery with electron radiotherapy.
Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Electrons; Female; Humans; Keloid; Male; Middle | 2023 |
Placental mesenchymal stem cells-secreted proenkephalin suppresses the p38 MAPK signaling to block hyperproliferation of keloid fibroblasts.
Topics: Animals; Cell Proliferation; Cells, Cultured; Female; Fibroblasts; Keloid; Mesenchymal Stem Cells; M | 2023 |
Identification of a potential bioinformatics-based biomarker in keloids and its correlation with immune infiltration.
Topics: Algorithms; Biomarkers; Cell Proliferation; Computational Biology; Humans; Inflammation; Keloid | 2023 |
Pruritus in keloid scars: mechanisms and treatments.
Topics: Cryotherapy; Humans; Inflammation; Keloid; Pain; Pruritus; Quality of Life | 2023 |
Needle-free electronically controlled jet injection with corticosteroids in recalcitrant keloid scars: a retrospective study and patient survey.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Injections, Jet; | 2023 |
hsa_circ_0037722 Drives Keloid Formation by Interacting with miR-140-3p and NR2F2.
Topics: Cell Proliferation; COUP Transcription Factor II; Fibroblasts; Humans; Keloid; MicroRNAs; Molecular | 2024 |
Keloidal atypical fibroxanthoma of the scalp.
Topics: Aged; Biomarkers, Tumor; Carcinoma, Squamous Cell; Diagnosis, Differential; Humans; Keloid; Melanoma | 2023 |
The upregulation of circFoxp1 influences keloid by promoting cell proliferation.
Topics: Cell Proliferation; Fibroblasts; Humans; In Situ Hybridization, Fluorescence; Keloid; RNA, Circular; | 2023 |
Efficacy of a multimodal approach of laser therapy for earlobe keloids management in dark population.
Topics: Adult; Carbon Dioxide; Ear, External; Female; Humans; Keloid; Laser Therapy; Male; Recurrence; Treat | 2023 |
Ear keloids: An innovative 3-steps combined treatment.
Topics: Humans; Inflammation; Keloid; Lasers, Gas; Light; Recurrence; Treatment Outcome | 2023 |
Keloids and associated comorbidities in underrepresented populations: a cross-sectional analysis of the All of Us database.
Topics: Comorbidity; Cross-Sectional Studies; Databases, Factual; Humans; Keloid; Population Health | 2023 |
Successful Treatment of Keloids and Hypertrophic Scars With Systemic and Intralesional Dupilumab.
Topics: Adult; Antibodies, Monoclonal, Humanized; Cicatrix, Hypertrophic; Female; Humans; Injections, Intral | 2023 |
Microneedle Electroporation for Intralesional Administration of Corticosteroid Treatment of Keloid Scar.
Topics: Adrenal Cortex Hormones; Electroporation; Electroporation Therapies; Humans; Injections, Intralesion | 2023 |
Pentoxifylline for the Prevention of Postsurgical Keloid Recurrence.
Topics: Administration, Oral; Adult; Aged; Combined Modality Therapy; Dermatologic Surgical Procedures; Feas | 2020 |
Connection between T regulatory cell enrichment and collagen deposition in keloid.
Topics: Adult; Case-Control Studies; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Collagen; | 2019 |
Long non-coding RNA HOXA11-AS induces type I collagen synthesis to stimulate keloid formation via sponging miR-124-3p and activation of Smad5 signaling.
Topics: Cell Proliferation; Cells, Cultured; Collagen Type I; Homeodomain Proteins; Humans; Keloid; MicroRNA | 2019 |
Demographic and clinical characteristics of keloids in an urban center in Sub-Sahara Africa.
Topics: Adult; Demography; Female; Humans; Keloid; Male; Nigeria; Pain; Visual Analog Scale; Wound Healing | 2019 |
Combination of 5-ALA photodynamic therapy, surgery and superficial X-ray for the treatment of keloid.
Topics: Adult; Aged; Aminolevulinic Acid; Female; Humans; Keloid; Male; Middle Aged; Photochemotherapy; X-Ra | 2020 |
A Novel Radiotherapy Approach for Keloids with Intrabeam.
Topics: Adult; Female; Follow-Up Studies; Humans; Keloid; Male; Middle Aged; X-Ray Therapy | 2019 |
Epidemiology and clinical features of keloids in Black Africans: a nested case-control study from Yaoundé, Cameroon.
Topics: Adolescent; Adult; Black People; Cameroon; Case-Control Studies; Child; Child, Preschool; Female; Hu | 2019 |
MiR-152-3p regulates cell proliferation, invasion and extracellular matrix expression through by targeting FOXF1 in keloid fibroblasts.
Topics: 3' Untranslated Regions; Adolescent; Adult; Cell Movement; Cell Proliferation; Cells, Cultured; Extr | 2019 |
[Giant right post-traumatic retroauricular keloid].
Topics: Biopsy; Dermatofibrosarcoma; Diagnosis, Differential; Ear; Humans; Keloid; Male; Skin Neoplasms; Wou | 2019 |
Antifibrotic Effects of High-Mobility Group Box 1 Protein Inhibitor (Glycyrrhizin) on Keloid Fibroblasts and Keloid Spheroids through Reduction of Autophagy and Induction of Apoptosis.
Topics: Apoptosis; Autophagy; Biomarkers; Cell Survival; Collagen; Extracellular Matrix; Fibroblasts; Fibros | 2019 |
STAT3 operates as a novel transcription factor that regulates NEDD4 in Keloid.
Topics: Base Sequence; Cells, Cultured; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Keloid | 2019 |
[Secondary surgical and medical treatment of scars].
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Plastic Surgery Procedures; Reoperation | 2019 |
Comparative Analysis of KGF-2 and bFGF in Prevention of Excessive Wound Healing and Scar Formation in a Corneal Alkali Burn Model.
Topics: Alkalies; Animals; Burns, Chemical; Cell Movement; Cell Proliferation; Cells, Cultured; Cornea; Corn | 2019 |
Are hypertrophic scars and keloids the same?
Topics: Actins; Cicatrix, Hypertrophic; Humans; Keloid; Muscle, Smooth; Phenotype | 2020 |
Triamcinolone Acetonide Suppresses Keloid Formation Through Enhancing Apoptosis in a Nude Mouse Model.
Topics: Animals; Apoptosis; Disease Models, Animal; In Situ Nick-End Labeling; Injections, Intralesional; Ke | 2019 |
Analyses of size and computed tomography densitometry parameters for prediction of keloid recurrence after postoperative electron beam radiation therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Densitometry; Female; Humans; Keloid; Male; Middl | 2020 |
CUDC‑907 reverses pathological phenotype of keloid fibroblasts in vitro and in vivo via dual inhibition of PI3K/Akt/mTOR signaling and HDAC2.
Topics: Adolescent; Adult; Aged; Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Movement; Cell Prolifer | 2019 |
Inhibition of microRNA-21-5p reduces keloid fibroblast autophagy and migration by targeting PTEN after electron beam irradiation.
Topics: Adult; Apoptosis; Autophagy; Cell Movement; Down-Regulation; Electrons; Female; Fibroblasts; Humans; | 2020 |
Geometric modeling and a retrospective cohort study on the usefulness of fascial tensile reductions in severe keloid surgery.
Topics: Adult; Aged; Female; Finite Element Analysis; Humans; Keloid; Male; Middle Aged; Recurrence; Retrosp | 2020 |
Keloid scar as a complication of triple therapy laser treatment of a recalcitrant facial port wine stain.
Topics: Child; Facial Dermatoses; Female; Humans; Keloid; Laser Therapy; Port-Wine Stain; Postoperative Comp | 2020 |
The integrative regulatory network of circRNA and microRNA in keloid scarring.
Topics: Adult; Binding Sites; Case-Control Studies; Cicatrix, Hypertrophic; Computational Biology; Gene Expr | 2020 |
Use of self-adherent silicone sheets in a pediatric burn patient: A case report and instructions for use.
Topics: Burns; Child, Preschool; Cicatrix, Hypertrophic; Female; Humans; Keloid; Occlusive Dressings; Silico | 2020 |
Combined treatment of hypertrophic and keloid scars with intralesional injection of corticosteroids and laser-assisted corticosteroid delivery.
Topics: Adolescent; Aged, 80 and over; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Glucocorti | 2019 |
Clinical Challenge and Call for Research on Keloid Disorder: Meeting Report from The 3rd International Keloid Research Foundation Symposium, Beijing 2019.
Topics: Alternative Splicing; Beijing; Cell Culture Techniques; Collagen; Congresses as Topic; Extracellular | 2020 |
Reconstructive complications of thrombophilia and keloid scarring: free flap surgery in a patient with mild protein S deficiency.
Topics: Free Tissue Flaps; Humans; Keloid; Plastic Surgery Procedures; Protein S Deficiency; Thrombophilia | 2019 |
HIF-1α promotes the keloid development through the activation of TGF-β/Smad and TLR4/MyD88/NF-κB pathways.
Topics: Animals; Apoptosis; Cell Hypoxia; Cell Proliferation; Fibroblasts; Gene Expression Regulation; Heter | 2019 |
BTXA regulates the epithelial-mesenchymal transition and autophagy of keloid fibroblasts via modulating miR-1587/miR-2392 targeted ZEB2.
Topics: Autophagy; Botulinum Toxins, Type A; Cell Line; Epithelial-Mesenchymal Transition; Fibroblasts; Huma | 2019 |
Therapeutic effect of interleukin-10 in keloid fibroblasts by suppression of TGF-β/Smad pathway.
Topics: Adult; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Female; Fibroblasts; H | 2019 |
Scarring and wound healing.
Topics: Adrenal Cortex Hormones; Aftercare; Humans; Keloid; Phototherapy; Sutures; Wound Healing | 2019 |
[Use of Anterolateral Thigh Free Flap in the Treatment of a Sternal Keloid].
Topics: Epidermal Cyst; Free Tissue Flaps; Humans; Keloid; Male; Middle Aged; Photography; Postoperative Com | 2019 |
Keloid lesions show increased IL-4/IL-13 signaling and respond to Th2-targeting dupilumab therapy.
Topics: Antibodies, Monoclonal, Humanized; Black or African American; Humans; Interleukin-13; Interleukin-4; | 2020 |
Keloid as an Underrecognized Potential Risk Factor for Post-Procedural Pulmonary Vein Stenosis.
Topics: Angioplasty, Balloon; Atrial Fibrillation; Humans; Keloid; Male; Middle Aged; Pulmonary Veno-Occlusi | 2020 |
Expression of Cathepsins B, D, and G by the Embryonic Stem Cell-Like Population within Human Keloid Tissues and Keloid-Derived Primary Cell Lines.
Topics: Blotting, Western; Cathepsin A; Cathepsin B; Cathepsin G; Cathepsins; Cell Line; Embryonic Stem Cell | 2019 |
Combining micro-plasma radio-frequency with hypofractionated electron-beam radiation as a novel treatment of keloids: A case series.
Topics: Adult; Combined Modality Therapy; Electrons; Female; Humans; Keloid; Male; Middle Aged; Postoperativ | 2019 |
Patch repair of deep wounds by mobilized fascia.
Topics: Animals; Biomarkers; Cell Movement; Fascia; Fibroblasts; Keloid; Mice, Inbred C57BL; Wound Healing | 2019 |
Evaluation of the efficacy of triamcinolone acetonide in the treatment of keloids by high-frequency ultrasound.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone Acetoni | 2020 |
Comments on "A new approach in the treatment of pediatric hypertrophic burn scars: Tixel-associated topical triamcinolone acetonide and 5-fluorouracil delivery".
Topics: Burns; Child; Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Triamcinolone Acetonide | 2020 |
Surgical excision combined with fully ablative carbon dioxide laser therapy and triamcinolone injections as a potential treatment for keloids in children.
Topics: Adolescent; Child; Child, Preschool; Combined Modality Therapy; Compression Bandages; Dermatologic S | 2020 |
IL-17 Induced Stromal Cell-Derived Factor-1 and Profibrotic Factor in Keloid-Derived Skin Fibroblasts via the STAT3 Pathway.
Topics: CD4-Positive T-Lymphocytes; Cells, Cultured; Chemokine CXCL12; Fibroblasts; Humans; Interleukin-17; | 2020 |
Comparative Efficacy and Safety of Common Therapies in Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Treatment Outcome | 2021 |
Spontaneous symmetrical giant keloids at the bilateral labia majora: a case report.
Topics: Female; Humans; Keloid; Middle Aged; Radiotherapy, Adjuvant; Recurrence; Surgical Flaps; Vulva | 2020 |
Comments on"Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomisedcontrol trial".
Topics: Burns; Cicatrix, Hypertrophic; Fluorouracil; Humans; Injections, Intralesional; Keloid; Triamcinolon | 2020 |
Long non-coding RNA HOXA11-AS accelerates the progression of keloid formation via miR-124-3p/TGFβR1 axis.
Topics: Adult; Apoptosis; Base Sequence; Disease Progression; Down-Regulation; Female; Fibroblasts; Humans; | 2020 |
Quercetin: A potential treatment for keloids.
Topics: Antioxidants; Humans; Keloid; Quercetin | 2019 |
Expression profile and bioinformatics analyses of circular RNAs in keloid and normal dermal fibroblasts.
Topics: Adult; Female; Fibroblasts; Gene Regulatory Networks; Humans; Keloid; Male; RNA, Circular; Transcrip | 2020 |
Heterogeneity of human fibroblasts isolated from hypertrophic scar.
Topics: Cicatrix, Hypertrophic; Fibroblasts; Humans; Immunohistochemistry; Keloid; Skin | 2019 |
Targeting of keloid with TRAIL and TRAIL-R2/DR5.
Topics: Apoptosis; Cell Line, Tumor; Fibroblasts; Humans; Keloid; Receptors, TNF-Related Apoptosis-Inducing | 2021 |
lncRNA-H19/miR-29a axis affected the viability and apoptosis of keloid fibroblasts through acting upon COL1A1 signaling.
Topics: Cell Movement; Cell Proliferation; Collagen Type I; Collagen Type I, alpha 1 Chain; Epithelial-Mesen | 2020 |
Hematoporphyrin monomethyl ether-mediated photodynamic therapy inhibits the growth of keloid graft by promoting fibroblast apoptosis and reducing vessel formation.
Topics: Adult; Animals; Apoptosis; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Fibrob | 2020 |
Syndecan-1 regulates extracellular matrix expression in keloid fibroblasts via TGF-β1/Smad and MAPK signaling pathways.
Topics: Extracellular Matrix; Fibroblasts; Humans; Keloid; MAP Kinase Signaling System; Smad Proteins; Synde | 2020 |
Correlation between serum IL 37 levels with keloid severity.
Topics: Cell Proliferation; Cells, Cultured; Cross-Sectional Studies; Extracellular Matrix; Fibroblasts; Hum | 2020 |
Multi-stage surgery combined with radiotherapy for treatment of giant anterior chest wall keloid: A case report.
Topics: Aged; Dermatologic Surgical Procedures; Female; Humans; Keloid; Postoperative Period; Radiotherapy, | 2020 |
[A survey of Belgian practice for non-malignant diseases].
Topics: Belgium; Gynecomastia; Humans; Keloid; Ossification, Heterotopic; Practice Patterns, Physicians'; Su | 2020 |
TSG-6 Inhibits the Growth of Keloid Fibroblasts Via Mediating the TGF-β1/Smad Signaling Pathway.
Topics: Cell Adhesion Molecules; Cell Proliferation; Cells, Cultured; Fibroblasts; Humans; Keloid; Signal Tr | 2021 |
Branching hypopigmentation following intralesional corticosteroid injection: Case report and review of the literature.
Topics: Child; Glucocorticoids; Humans; Hypopigmentation; Injections, Intralesional; Keloid; Male; Triamcino | 2020 |
A novel experimental model for studying efficacy of cryosurgery in keloids.
Topics: Cryosurgery; Humans; Keloid; Models, Theoretical; Needles; Skin | 2020 |
Comparative Efficacy and Safety of Common Therapies in Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Treatment Outcome | 2021 |
Darier and Ferrand's dermatofibrosarcoma: A carcinologic and cosmetologic challenge in a low-income country.
Topics: Adult; Burkina Faso; Dermatofibrosarcoma; Dermatologic Surgical Procedures; Developing Countries; Hu | 2020 |
Are there differences between the performances of keloids and hypertrophic scars when applying non-surgical treatments?
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Skin | 2022 |
Quantitative Assessment of Keloids Using Ultrasound Shear Wave Elastography.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Elasticity Imaging Techniques; | 2020 |
Clinical features of collagen VI-related dystrophies: A large Brazilian cohort.
Topics: Adolescent; Adult; Age of Onset; Brazil; Child; Cohort Studies; Collagen Type VI; Contracture; Disea | 2020 |
Inhibition of growth of Asian keloid cells with human umbilical cord Wharton's jelly stem cell-conditioned medium.
Topics: Animals; Cell Differentiation; Cell Proliferation; Culture Media, Conditioned; Humans; Keloid; Mesen | 2020 |
Analysis of Scars and Keloids by Focused Ion Beam/Scanning Electron Microscopy: Distinguishing Between Hypertrophic Scars and Keloids.
Topics: Cell Differentiation; Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid; Microscopy, Electron, Sca | 2020 |
Critical role and potential therapeutic efficacy of interleukin-37 in the pathogenesis of keloid scarring.
Topics: Cicatrix, Hypertrophic; Humans; Interleukin-1; Interleukins; Keloid | 2020 |
Letter to the Editor Regarding: Bao Y, Xu S, Pan Z, et al. Comparative Efficacy and Safety of Common Therapies in Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis. Aesth Plast Surg, 2019.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid | 2021 |
Influence of age on scar tissue: A retrospective study on the differences in scar tissue development between children and adults.
Topics: Adult; Age Factors; Child; Cicatrix, Hypertrophic; Cohort Studies; Female; Humans; Keloid; Male; Ret | 2020 |
Treatment of keloids using 5-fluorouracil in combination with crystalline triamcinolone acetonide suspension: evaluating therapeutic effects by using non-invasive objective measures.
Topics: Fluorouracil; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone Acetonide | 2020 |
Chondroitin Sulfate Promotes the Proliferation of Keloid Fibroblasts Through Activation of the Integrin and Protein Kinase B Pathways.
Topics: Adult; Aged; Aged, 80 and over; Cell Proliferation; Cells, Cultured; Chondroitin Sulfates; Female; F | 2020 |
Angioleiomyoma of the lumbo-sacral region with unusual keloid-like collagen fibers.
Topics: Angiomyoma; Collagen; Diagnosis, Differential; Humans; Keloid; Lumbosacral Region; Male; Middle Aged | 2020 |
Overexpression of miR-133a-3p inhibits fibrosis and proliferation of keloid fibroblasts by regulating IRF5 to inhibit the TGF-β/Smad2 pathway.
Topics: Adolescent; Adult; Apoptosis; Base Sequence; Biomarkers; Cell Proliferation; Cell Survival; Extracel | 2020 |
MicroRNA-21 may be involved in the therapeutic effects of Galla chinensis ointment on keloid.
Topics: Animals; Biomarkers; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fibroblasts; Humans; Imm | 2020 |
Histopathologic and dermoscopic features of 42 cases of folliculitis decalvans: A case series.
Topics: Alopecia; Fibrosis; Folliculitis; Humans; Keloid; Retrospective Studies | 2021 |
The histotopographic features of formation of keloid scars of maxillofacial localization.
Topics: Biopsy; Humans; Keloid | 2020 |
Auricular keloid management in Asian skin: Clinical outcome of intralesional excision and postoperative triamcinolone acetonide intralesional injection.
Topics: Adult; Combined Modality Therapy; Female; Humans; Injections, Intralesional; Keloid; Male; Skin; Tre | 2020 |
Are Prophylactic Measures Necessary to Prevent Recurrence of Penile Keloids?
Topics: Anti-Inflammatory Agents; Betamethasone; Child, Preschool; Circumcision, Male; Humans; Keloid; Male; | 2020 |
Wnt Signaling Pathway Proteins in Scar, Hypertrophic Scar, and Keloid: Evidence for a Continuum?
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Wnt Signaling Pathway; Wound Healing | 2020 |
Hypoxia and HIF-1α Regulate Collagen Production in Keloids.
Topics: Cell Hypoxia; Cells, Cultured; Collagen; Fibroblasts; Humans; Hypoxia-Inducible Factor 1, alpha Subu | 2020 |
Knockdown of fibronectin extra domain B suppresses TGF-β1-mediated cell proliferation and collagen deposition in keloid fibroblasts via AKT/ERK signaling pathway.
Topics: Apoptosis; Cell Proliferation; Collagen; Fibroblasts; Fibronectins; Gene Knockdown Techniques; Human | 2020 |
Adiponectin-Based Peptide (ADP355) Inhibits Transforming Growth Factor-β1-Induced Fibrosis in Keloids.
Topics: Adiponectin; AMP-Activated Protein Kinase Kinases; Animals; Cell Survival; Cells, Cultured; Cicatrix | 2020 |
miR-4417 suppresses keloid fibrosis growth by inhibiting CyclinD1.
Topics: Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclin D1; Down-Regulation; Fibroblas | 2020 |
Combined surgical excision and electron external beam radiation improves the treatment of keloids: A descriptive study.
Topics: Adult; Aged; Combined Modality Therapy; Electrons; Humans; Keloid; Middle Aged; Radiotherapy, Adjuva | 2020 |
TM4SF1 involves in miR-1-3p/miR-214-5p-mediated inhibition of the migration and proliferation in keloid by regulating AKT/ERK signaling.
Topics: Antigens, Surface; Cell Movement; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Hu | 2020 |
Topical delivery of 5-fluorouracil-loaded carboxymethyl chitosan nanoparticles using microneedles for keloid treatment.
Topics: Chitosan; Drug Delivery Systems; Fluorouracil; Humans; Keloid; Nanoparticles | 2021 |
Continuous tension reduction to prevent keloid recurrence after surgical excision: Preliminary experience in Asian patients.
Topics: Humans; Keloid; Plastic Surgery Procedures; Recurrence; Treatment Outcome; Wound Healing | 2020 |
Familial keloids associated with familial Noonan's syndrome treated with surgery followed by radiotherapy: First case from Albania.
Topics: Albania; Humans; Keloid; Noonan Syndrome | 2020 |
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Topics: Actins; Cell Cycle; Cell Movement; Cell Survival; Cells, Cultured; Collagen; Fibroblasts; Humans; In | 2020 |
[Examining the pathogenesis and therapeutic strategy of keloids from the perspective of systemic inflammation].
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Keloid; Treatment Outcome | 2020 |
[Clinical effect of Zhang's super tension-relieving suture for high-tension wound closure].
Topics: Adolescent; Adult; Aged; Child; China; Cicatrix, Hypertrophic; Female; Humans; Injections, Intralesi | 2020 |
Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Pain; Treatment Outcome; Verapamil | 2021 |
Sumoylation enhances the activity of the TGF-β/SMAD and HIF-1 signaling pathways in keloids.
Topics: Extracellular Matrix; Fibroblasts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Keloid; Signal | 2020 |
Silicone sheets and new gels to treat hypertrophic scars and keloids: A short review.
Topics: Cicatrix, Hypertrophic; Gels; Humans; Keloid; Silicone Gels; Skin | 2020 |
[Keloid of the external auditory canal].
Topics: Ear Canal; Ear Neoplasms; Humans; Keloid | 2020 |
Treatment of Keloids by Surgical Excision Combined With 5-Fluorouracil and Betamethasone Injection.
Topics: Adult; Betamethasone; Combined Modality Therapy; Dermatologic Surgical Procedures; Female; Fluoroura | 2021 |
Laser-assisted topical steroid application versus steroid injection for treating keloids: A split side study.
Topics: Humans; Injections, Intralesional; Keloid; Lasers, Solid-State; Steroids; Treatment Outcome | 2021 |
Resveratrol inhibits proliferation and promotes apoptosis of keloid fibroblasts by targeting HIF-1α.
Topics: Adult; Apoptosis; Cell Proliferation; Cells, Cultured; Down-Regulation; Female; Fibroblasts; Humans; | 2020 |
Long non-coding RNA CACNA1G-AS1 promotes proliferation and invasion and inhibits apoptosis by regulating expression of miR-205 in human keloid fibroblasts.
Topics: Apoptosis; Case-Control Studies; Cell Movement; Cell Proliferation; Cells, Cultured; Fibroblasts; Ge | 2020 |
Optimal indications and limitations of endoscopic transorbital superior eyelid surgery for spheno-orbital meningiomas.
Topics: Adult; Aged; Cerebrospinal Fluid Leak; Endoscopy; Eyelids; Female; Humans; Keloid; Magnetic Resonanc | 2020 |
Low-Grade Myofibroblastic Sarcoma Arising From Keloid Scar on the Chest Wall After Thoracic Surgery.
Topics: Aged; Humans; Keloid; Male; Neoplasm Grading; Postoperative Complications; Sarcoma; Skin Neoplasms; | 2020 |
Modified injection technique for improving the treatment of keloids.
Topics: Humans; Keloid; Recurrence | 2020 |
Invited Discussion On: Efficacy and Safety of Intralesional Triamcinolone Versus Combination of Triamcinolone with 5-Fluorouracil in the Treatment of Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Injections, Intralesional; Keloid; Triamcinolone | 2020 |
Successful cosmetic outcome of earlobe keloid after surgical excision and topical imiquimod 5.
Topics: Aminoquinolines; Ear Diseases; Esthetics; Humans; Imiquimod; Keloid | 2020 |
Luteolin affects keloid fibroblast proliferation and apoptosis by regulating FRAT1 gene expression.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Proliferation; Fibroblasts; Gene Expression Re | 2020 |
Treatment of keloids with a single dose of low-energy superficial X-ray radiation to prevent recurrence after surgical excision: An in vitro and in vivo study.
Topics: Adult; Aged; Cells, Cultured; Female; Fibroblasts; Humans; Keloid; Male; Middle Aged; Radiotherapy D | 2020 |
[Muscle weakness, joint laxity and keloids. A more than suggestive association].
Topics: Humans; Joint Instability; Keloid; Knee Joint; Muscle Weakness; Range of Motion, Articular | 2021 |
Dipeptidyl Peptidase-4 Inhibitor Reduces the Risk of Developing Hypertrophic Scars and Keloids following Median Sternotomy in Diabetic Patients: A Nationwide Retrospective Cohort Study Using the National Database of Health Insurance Claims of Japan.
Topics: Adult; Aged; Cicatrix, Hypertrophic; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; | 2020 |
Comparative evaluation of therapeutic efficacy and safety of intralesional triamcinolone acetonide injection vs intralesional radiofrequency with intralesional triamcinolone acetonide in treatment of keloids.
Topics: Drug Therapy, Combination; Female; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Male; | 2020 |
Potentials for implementing pressure-controlled jet injection in management of keloids with intralesional 5FU and corticosteroids.
Topics: Adrenal Cortex Hormones; Fluorouracil; Humans; Injections, Intralesional; Injections, Jet; Keloid; R | 2020 |
Assessment of laser-assisted delivery vs intralesional injection of botulinum toxin A in treatment of hypertrophic scars and keloids.
Topics: Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Quality | 2020 |
Use of a smartphone for imaging, modelling, and evaluation of keloids.
Topics: Adult; Burns; China; Female; Humans; Imaging, Three-Dimensional; Keloid; Male; Middle Aged; Reproduc | 2020 |
Response to Letter to the Editor: Comments on "Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids".
Topics: Burns; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; V | 2020 |
Re: Keloid Formation after Pediatric Male Genital Surgeries: An Uncommon and Difficult Problem to Manage.
Topics: Child; Genitalia, Male; Humans; Keloid; Male; Urogenital Surgical Procedures | 2020 |
Comments on "Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids".
Topics: Burns; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Triamcinolone Acetonide; V | 2020 |
Regulation of glycolysis and the Warburg effect in wound healing.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Case-Control Studies; Female; Glucos | 2020 |
[Second ear piercing for aesthetic purposes and appearance of pathological scars in negroids: About 172 observations in an endemic area of keloids].
Topics: Adult; Body Piercing; Cicatrix, Hypertrophic; Esthetics; Female; Humans; Keloid; Retrospective Studi | 2021 |
Nonsurgical Management of Hypertrophic Scars: Evidence-Based Therapies, Standard Practices, and Emerging Methods: An Update.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Reference Standards | 2020 |
Intralesional Cryotherapy Using Disposable Needles.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Disposable Equipment; Equipment Design; Humans; Injections, Int | 2021 |
Letter to the Editor on Objective evaluation of an occlusive overnight intensive patch containing onion extract and allantoin for hypertrophic scars.
Topics: Allantoin; Cicatrix, Hypertrophic; Humans; Keloid; Onions; Plant Extracts | 2020 |
Keystone-designed perforator island flaps for reconstruction after chest keloid excision: A retrospective case series.
Topics: Humans; Keloid; Perforator Flap; Plastic Surgery Procedures; Retrospective Studies; Thorax; Treatmen | 2021 |
Experience Treating Earlobe Keloids with Laser Diode 980nm Excision Followed by Triamcinolone Infiltration.
Topics: Humans; Keloid; Lasers, Semiconductor; Recurrence; Retrospective Studies; Treatment Outcome; Triamci | 2021 |
Fat Injection for Cases of Severe Burn Outcomes: A New Perspective of Scar Remodeling and Reduction.
Topics: Adipose Tissue; Adult; Burns; Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Plastic Surgery Proc | 2020 |
Paraovarian Cyst Torsion in a Patient with Rubinstein-Taybi Syndrome: A Case Report.
Topics: Abdominal Pain; Adolescent; Cystectomy; Fallopian Tube Diseases; Female; Hirsutism; Humans; Keloid; | 2021 |
Cutaneous Leiomyoma Mimicking a Keloid.
Topics: Adult; Biopsy; Diagnosis, Differential; Female; Humans; Keloid; Leiomyoma; Male; Middle Aged; Skin N | 2020 |
Contemporary treatment of keloids: A 10-year institutional experience with medical management, surgical excision, and radiation therapy.
Topics: Adult; Dermatologic Surgical Procedures; Esthetics; Female; Humans; Keloid; Male; Middle Aged; Radio | 2021 |
Long non-coding RNA LINC01116 accelerates the progression of keloid formation by regulating miR-203/SMAD5 axis.
Topics: China; Humans; Keloid; MicroRNAs; RNA, Long Noncoding; Smad5 Protein | 2021 |
Downregulation of Epac Reduces Fibrosis and Induces Apoptosis Through Akt Signaling in Human Keloid Fibroblasts.
Topics: Apoptosis; Cells, Cultured; Dermis; Down-Regulation; Fibroblasts; Fibrosis; Guanine Nucleotide Excha | 2021 |
An open source pipeline for design of experiments for hyperelastic models of the skin with applications to keloids.
Topics: Biomechanical Phenomena; Elasticity; Finite Element Analysis; Humans; Keloid; Models, Biological; Sk | 2020 |
Nonmuscle Myosin II Activation Regulates Cell Proliferation, Cell Contraction, and Myofibroblast Differentiation in Keloid-Derived Fibroblasts.
Topics: Adult; Aged; Case-Control Studies; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collag | 2020 |
Leaf Extract of Aerva javanica Suppresses Excessive Growth of Granulation Tissue in Horses.
Topics: Amaranthaceae; Animals; Granulation Tissue; Horse Diseases; Horses; Keloid; Plant Extracts; Wound He | 2020 |
Combination therapy of refractory keloid with ultrapulse fractional carbon dioxide (CO
Topics: Asian People; Carbon Dioxide; Humans; Keloid; Lasers, Gas; Prospective Studies; Treatment Outcome; T | 2020 |
Keloid Formation after Circumcision: A Case Report and Current Literature Review.
Topics: Child; Circumcision, Male; Humans; Keloid; Male; Penile Diseases; Penis | 2020 |
S2k guidelines for the therapy of pathological scars (hypertrophic scars and keloids) - Update 2020.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Skin | 2021 |
Heterogeneous Features of Keloids Assessed by Laser Speckle Contrast Imaging: A Cross-Sectional Study.
Topics: Cross-Sectional Studies; Humans; Keloid; Laser Speckle Contrast Imaging; Lasers; Skin | 2021 |
[Anatomoclinical and immunohistochemical study of 8 cases of dermatomyofibroma].
Topics: Dermis; Diagnosis, Differential; Female; Humans; Immunohistochemistry; Keloid; Male; Skin Neoplasms | 2020 |
Wubeizi Ointment Suppresses Keloid Formation through Modulation of the mTOR Pathway.
Topics: Adult; Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Drugs, Chinese Herbal; Female; Fibro | 2020 |
Methodological quality of clinical trials of keloid scars.
Topics: Cicatrix, Hypertrophic; Clinical Trials as Topic; Humans; Keloid; Pain; Quality of Life | 2020 |
Efficacy of Surgical Excision and Brachytherapy in the Treatment of Keloids: A Retrospective Cohort Study.
Topics: Adult; Brachytherapy; Cryosurgery; Dermatologic Surgical Procedures; Female; Follow-Up Studies; Huma | 2020 |
Tissue-remodelling M2 Macrophages Recruits Matrix Metallo-proteinase-9 for Cryotherapy-induced Fibrotic Resolution during Keloid Treatment.
Topics: Cryotherapy; Humans; Injections, Intralesional; Keloid; Macrophages; Matrix Metalloproteinase 9; Ret | 2020 |
Hydrocolloid dressings can be used to treat hypertrophic scars: An outpatient dermatology service devoted to treat keloids and challenging scars.
Topics: Ambulatory Care; Bandages, Hydrocolloid; Cicatrix, Hypertrophic; Dermatology; Humans; Keloid; Outpat | 2020 |
Potential treatment of keloid pathogenesis with follistatin 288 by blocking the activin molecular pathway.
Topics: Cells, Cultured; Connective Tissue Growth Factor; Elastin; Fibroblasts; Follistatin; Gene Expression | 2021 |
Contribution of Autophagy-Notch1-Mediated NLRP3 Inflammasome Activation to Chronic Inflammation and Fibrosis in Keloid Fibroblasts.
Topics: Adolescent; Adult; Aged; Autophagy; Chronic Disease; Female; Fibroblasts; Humans; Inflammasomes; Inf | 2020 |
Metformin Inhibits Transforming Growth Factor β-Induced Fibrogenic Response of Human Dermal Fibroblasts and Suppresses Fibrosis in Keloid Spheroids.
Topics: Cells, Cultured; Fibroblasts; Fibrosis; Humans; Keloid; Metformin; Transforming Growth Factor beta; | 2021 |
NEAT1 Knockdown Inhibits Keloid Fibroblast Progression by miR-196b-5p/FGF2 Axis.
Topics: Cell Movement; Cell Survival; Cells, Cultured; Extracellular Matrix Proteins; Fibroblast Growth Fact | 2021 |
Impaired collagen fibril assembly in keloids with enhanced expression of lumican and collagen V.
Topics: Adult; Collagen Type V; Female; Gene Expression Regulation; Humans; Keloid; Lumican; Male; Middle Ag | 2021 |
miR-194-5p serves a suppressive role in human keloid fibroblasts via targeting NR2F2.
Topics: Apoptosis; Cell Line; Cell Movement; Cell Proliferation; Computational Biology; COUP Transcription F | 2021 |
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Topics: Actins; Adolescent; Adult; Apoptosis; Cell Movement; Cell Proliferation; Core Binding Factor Alpha 1 | 2021 |
Secondary data mining of GEO database for long non-coding RNA and Competing endogenous RNA network in keloid-prone individuals.
Topics: Data Mining; Databases, Genetic; Gene Regulatory Networks; Humans; Keloid; MicroRNAs; RNA, Long Nonc | 2020 |
Intralesional cryosurgery of keloids: required treatment hold time.
Topics: Cryosurgery; Humans; Injections, Intralesional; Keloid; Treatment Outcome | 2021 |
Human CD206+ Macrophages Show Antifibrotic Effects on Human Fibroblasts through an IL-6-Dependent Mechanism In Vitro.
Topics: Cells, Cultured; Cicatrix, Hypertrophic; Coculture Techniques; Culture Media, Conditioned; Fibroblas | 2021 |
[Effects of Regulating Smad7 Gene on Epithelial-Mesenchymal Transition in Keloid Keratinocyte].
Topics: Cadherins; Cell Line, Tumor; Cell Proliferation; Epithelial-Mesenchymal Transition; Humans; Keloid; | 2020 |
Treatment of Pain in Keloids Using Only a Long-Pulsed 1064 nm Nd:YAG Laser.
Topics: Humans; Keloid; Lasers, Solid-State; Low-Level Light Therapy; Pain; Treatment Outcome | 2021 |
Big ear keloid response to PDL laser.
Topics: Humans; Keloid; Lasers | 2021 |
Nodular morphea keloidal type: A rare case with paradigmatic histopathology significantly accompanied by a flawless surgical scar.
Topics: Breast Neoplasms; Female; Humans; Keloid; Middle Aged; Scleroderma, Localized | 2021 |
LncRNA HOXA11-AS Aggravates Keloid Progression by the Regulation of HOXA11-AS-miR-205-5p-FOXM1 Pathway.
Topics: Adult; Disease Progression; Female; Forkhead Box Protein M1; Gene Expression Regulation; Humans; Kel | 2021 |
Altered glucose metabolism and cell function in keloid fibroblasts under hypoxia.
Topics: Animals; Cell Hypoxia; Fibroblasts; Glucose; Glycolysis; Hypoxia; Keloid; Phosphatidylinositol 3-Kin | 2021 |
Long-term outcomes and recurrence-free interval after the treatment of keloids with a standardized protocol.
Topics: Adult; Aftercare; Aged; Child; Clinical Protocols; Female; Glucocorticoids; Humans; Japan; Kaplan-Me | 2021 |
Treatment of hypertrophic scars and keloids using an intralesional 1470 nm bare-fibre diode laser: a novel efficient minimally-invasive technique.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Humans; Keloid; La | 2020 |
Effects of in vivo application of an overnight patch containing Allium cepa, allantoin, and pentaglycan on hypertrophic scars and keloids: Clinical, videocapillaroscopic, and ultrasonographic study.
Topics: Allantoin; Cicatrix, Hypertrophic; Humans; Keloid; Onions; Plant Extracts | 2021 |
Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway.
Topics: Activating Transcription Factor 3; Apoptosis; Cell Proliferation; Cells, Cultured; Collagen; Fibrobl | 2021 |
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
Topics: Burns; Cell Proliferation; Gene Regulatory Networks; Humans; Keloid; MicroRNAs | 2021 |
RNA Sequencing Keloid Transcriptome Associates Keloids With Th2, Th1, Th17/Th22, and JAK3-Skewing.
Topics: Adult; Aged; Biomarkers; Female; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; H | 2020 |
THE EFFECT OF PHOTODYNAMIC THERAPY AND PLATELET-ENRICHED PLASMA ON THE HEALING OF SKIN RADIATION ULCERS INFECTED BY STAPHYLOCOCCUS AUREUS.
Topics: Animals; Humans; Keloid; Male; Methylene Blue; Photochemotherapy; Photosensitizing Agents; Platelet- | 2020 |
Comparative Study between Nd-YAG laser, fractional CO2 Laser, and combined Nd-YAG with fractional CO2 Laser in the Management of keloid: clinical and molecular Study.
Topics: Humans; Keloid; Lasers, Gas; Lasers, Solid-State; Treatment Outcome | 2021 |
LncRNA H19 promotes keloid formation through targeting the miR-769-5p/EIF3A pathway.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Eukaryotic Initiation Factor-3; Extr | 2021 |
A hesitated approach: primary radiotherapy for keloids-a case series.
Topics: Electrons; Humans; Keloid; Neoplasm Recurrence, Local; Radiation Dosage; Treatment Outcome | 2021 |
Immediate Postoperative Radiation Therapy after Free Tissue Transfer for Keloid Treatment.
Topics: Combined Modality Therapy; Free Tissue Flaps; Humans; Keloid; Magnetic Resonance Imaging; Male; Midd | 2021 |
Arthrofibrosis after total knee arthroplasty: patients with keloids at risk.
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Female; Follow-Up Studies; Humans; Joint D | 2021 |
Identification of differentially expressed circular RNAs in keloid and normal skin tissue by high-throughput sequencing.
Topics: High-Throughput Nucleotide Sequencing; Humans; Keloid; MicroRNAs; RNA, Circular; Skin | 2021 |
The association between keloid and osteoporosis: real-world evidence.
Topics: Collagen; Comorbidity; Humans; Incidence; Keloid; Osteoporosis | 2021 |
Halofuginone regulates keloid fibroblast fibrotic response to TGF-β induction.
Topics: Actins; Adult; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type I; Extracellular Ma | 2021 |
Scar tissue I wish you saw: Patient expectations regarding scar treatment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cicatrix, Hypertrophic; Humans; Hypertrophy; Keloid; Mid | 2021 |
Downregulation of CR6-interacting factor 1 suppresses keloid fibroblast growth via the TGF-β/Smad signaling pathway.
Topics: Adolescent; Adult; Case-Control Studies; Cell Cycle; Cell Cycle Proteins; Cell Movement; Cell Prolif | 2021 |
Does Keloid Histology Influence Recurrence?
Topics: Adolescent; Adult; Aged; Connective Tissue Cells; Female; Fibroblasts; Humans; Keloid; Longitudinal | 2021 |
Association between MeCP2 and Smad7 in the pathogenesis and development of pathological scars.
Topics: Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid; Methyl-CpG-Binding Protein 2; RNA, Messenger; S | 2021 |
Does vitamin D deficiency predispose to keloids via dysregulation of koebnerisin (S100A15)? A case-control study.
Topics: Antimicrobial Peptides; Case-Control Studies; Fibroblasts; Humans; Keloid; S100 Calcium Binding Prot | 2021 |
Commentary on: Comparing the Efficacy and Safety of Intralesional Verapamil With Intralesional Triamcinolone Acetonide in Treatment of Hypertrophic Scars and Keloids: A Meta-Analysis of Randomized Controlled Trials.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as T | 2021 |
A massive mandibular keloid with severe infection: What is your treatment?
Topics: Acne Vulgaris; Aminolevulinic Acid; Humans; Keloid; Photochemotherapy; Photosensitizing Agents; Trea | 2021 |
First Clinical Experience of Tungsten Rubber Electron Adaptive Therapy With Real-time Variable-shape Tungsten Rubber.
Topics: Adult; Ear Diseases; Female; Humans; Keloid; Postoperative Care; Radiation Protection; Radiotherapy | 2021 |
The Keloid Intervention Benefit Inventory 21: A New Assessment Tool for the Quality of Life of Patients with Auricular Keloids.
Topics: Humans; Keloid; Psychometrics; Quality of Life; Reproducibility of Results; Surveys and Questionnair | 2021 |
Laser-assisted topical steroid application vs steroid injection for treating keloids: A split side study.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Lasers; Steroids | 2021 |
Migraines and keloids: a 15-year Taiwan claim database analysis.
Topics: Adult; Female; Humans; Incidence; Keloid; Migraine Disorders; Risk Factors; Taiwan | 2022 |
Antifibrotic effects of Hypocrellin A combined with LED red light irradiation on keloid fibroblasts by counteracting the TGF-β/Smad/autophagy/apoptosis signalling pathway.
Topics: Apoptosis; Autophagy; Cell Proliferation; Cells, Cultured; Fibroblasts; Humans; Keloid; Light; Peryl | 2021 |
A retrospective study of hypofractionated radiotherapy for keloids in 100 cases.
Topics: Adolescent; Adult; Aged; Brachytherapy; Child; Female; Humans; Keloid; Male; Middle Aged; Radiation | 2021 |
PAX5 activates telomerase activity and proliferation in keloid fibroblasts by transcriptional regulation of SND1, thus promoting keloid growth in burn-injured skin.
Topics: Adult; Animals; Burns; Cell Proliferation; Cell Survival; Cells, Cultured; Endonucleases; Female; Fi | 2021 |
[Bibliometric and visual analysis of current status and trends of international research on keloids].
Topics: Bibliometrics; China; Cicatrix, Hypertrophic; Humans; Keloid; Publications | 2021 |
Safety assessment of the prophylactic use of silicone gel sheets (Lady Care
Topics: Adult; Cesarean Section; Cicatrix, Hypertrophic; Female; Humans; Incidence; Keloid; Postoperative Co | 2021 |
circNRIP1 facilitates keloid progression via FXR1‑mediated upregulation of miR‑503‑3p and miR‑503‑5p.
Topics: Cell Proliferation; Female; Fibroblasts; Humans; Keloid; Male; MicroRNAs; RNA-Binding Proteins; RNA, | 2021 |
Blood perfusion in hypertrophic scars and keloids studied by laser speckle contrast imaging.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laser Speckle Contrast Imaging; Perfusion | 2021 |
Scalp Reconstruction in Delayed Diagnosed Dermal Leiomyosarcoma Mimicking Keloid Scar.
Topics: Aged; Female; Humans; Keloid; Leiomyosarcoma; Plastic Surgery Procedures; Scalp; Skin Transplantatio | 2021 |
Ameliorating Fibrotic Phenotypes of Keloid Dermal Fibroblasts through an Epidermal Growth Factor-Mediated Extracellular Matrix Remodeling.
Topics: Adult; Cell Movement; Cells, Cultured; Cicatrix, Hypertrophic; Elastic Modulus; Enzymes; Epidermal G | 2021 |
Association of Leptin Receptor Gene Polymorphisms with Keloids in the Chinese Han Population.
Topics: Adult; Asian People; Case-Control Studies; China; Cohort Studies; Ethnicity; Female; Gene Frequency; | 2021 |
[Correlation study of
Topics: Adult; Case-Control Studies; Correlation of Data; Female; Humans; Keloid; Male; Middle Aged; Retrosp | 2021 |
Phosphoproteome and Biological Evidence Revealed Abnormal Calcium Homeostasis in Keloid Fibroblasts and Induction of Aberrant Platelet Aggregation.
Topics: Calcium; Cells, Cultured; Fibroblasts; Homeostasis; Humans; Keloid; Platelet Aggregation; Transformi | 2021 |
The "Matrisome" reveals the characterization of skin keloid microenvironment.
Topics: Collagen; Extracellular Matrix; Extracellular Matrix Proteins; Gene Expression Regulation; Humans; K | 2021 |
Role of vitamin D in treatment of keloid.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Treatmen | 2022 |
A new therapeutic protocol for the treatment of keloid scars: a retrospective study.
Topics: Cicatrix; Glucocorticoids; Humans; Keloid; Retrospective Studies; Surgical Flaps; Treatment Outcome; | 2021 |
Commentary on "Comparative effectiveness in the treatment of keloids: Outcomes between medical management, surgical excision, and radiation therapy over 10 years."
Topics: Follow-Up Studies; Humans; Keloid; Treatment Outcome | 2021 |
Large chest keloids treatment with expanded parasternal intercostal perforator flap.
Topics: Adult; Humans; Keloid; Middle Aged; Perforator Flap; Retrospective Studies; Thoracic Surgical Proced | 2021 |
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model.
Topics: Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Fibroblasts; Humans; Keloid; Male; M | 2021 |
RNA-sequencing reveals plantar keloid has potential bone/cartilage characteristics.
Topics: Cartilage; Female; Foot; Humans; Keloid; Middle Aged; RNA | 2021 |
Warburg effect in keloids: A unique feature different from other types of scars.
Topics: Burns; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid | 2022 |
Laser Speckle Contrast Imaging for the Objective Assessment of Blood Perfusion in Keloids Treated With Dual-Wavelength Laser Therapy.
Topics: Adolescent; Adult; Female; Humans; Keloid; Laser Speckle Contrast Imaging; Lasers, Dye; Low-Level Li | 2021 |
Analysis of HOX gene expression and the effects of HOXA9 overexpression in fibroblasts derived from keloid lesions and normal skin.
Topics: Cells, Cultured; Fibroblasts; Gene Expression; Genes, Homeobox; Humans; Keloid; Wound Healing | 2021 |
Commentary on: Synergic Effect of Botulinum Toxin Type A and Triamcinolone Alleviates Scar Pruritus by Modulating Epidermal Hyperinnervation: A Preliminary Report.
Topics: Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Humans; Keloid; Pruritus; Triamcinolone | 2021 |
Screw-loaded compression device for auricular keloid.
Topics: Bone Screws; Ear, External; Humans; Keloid; Pressure | 2022 |
Different Types of Auricular Keloids and Treatment by Intralesional Cryosurgery: Best Practice for Obtaining Long-Lasting Clinical Results.
Topics: Cryosurgery; Ear Auricle; Humans; Injections, Intralesional; Keloid; Practice Guidelines as Topic; T | 2022 |
Assessment of various intralesional injections in keloid: comparative analysis.
Topics: Fluorouracil; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone Acetonide; | 2022 |
Bioinformatic Analysis of Key Genes and Pathways Related to Keloids.
Topics: Computational Biology; Down-Regulation; Gene Expression Profiling; Gene Ontology; Gene Regulatory Ne | 2021 |
[Tumor characteristics of keloid].
Topics: Apoptosis; Cicatrix, Hypertrophic; Humans; Keloid; Neoplasms; Skin | 2021 |
Keloids.
Topics: Humans; Keloid | 2021 |
[Deliberation on the similarities and differences of the diagnosis and treatment of scars and keloids in China and Japan].
Topics: China; Cicatrix, Hypertrophic; Consensus; Humans; Japan; Keloid | 2021 |
Multifaceted array-based keloidal gene expression profiling reveals specific MDFI upregulation in keloid lesions.
Topics: Diagnosis, Differential; Fibroblasts; Gene Expression; Gene Expression Profiling; Humans; Immunohist | 2021 |
[Atypical keloids with an unusual myofibroblastic differentiation in a patient with acne vulgaris].
Topics: Acne Vulgaris; Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Cryotherapy; Humans; Injections, Int | 2022 |
Phenalen-1-one-mediated photodynamic therapy inhibits keloid graft progression by reducing vessel formation and promoting fibroblast apoptosis.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Fibroblasts; Keloid; Mice; Mice, Nude; Phen | 2021 |
Risk of cancer development in patients with keloids.
Topics: Adult; Case-Control Studies; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Keloid; Mal | 2021 |
Keloid tissue analysis discredits a role for myofibroblasts in disease pathogenesis.
Topics: Biomarkers; Cicatrix, Hypertrophic; Humans; Keloid; Myofibroblasts; Wound Healing | 2021 |
Reply: Dipeptidyl Peptidase-4 Inhibitor Reduces the Risk of Developing Hypertrophic Scars and Keloids following Median Sternotomy in Diabetic Patients: A Nationwide Retrospective Cohort Study Using the National Database of Health Insurance Claims of Japan
Topics: Cicatrix, Hypertrophic; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Dipeptidyl-Peptidases | 2021 |
Dipeptidyl Peptidase-4 Inhibitor Reduces the Risk of Developing Hypertrophic Scars and Keloids following Median Sternotomy in Diabetic Patients: A Nationwide Retrospective Cohort Study Using the National Database of Health Insurance Claims of Japan.
Topics: Cicatrix, Hypertrophic; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Dipeptidyl-Peptidases | 2021 |
Suppurative keloids: a complication of severe keloid disease.
Topics: Adult; Humans; Keloid; Male; Medical History Taking; Retrospective Studies; Skin; Suppuration | 2021 |
A three-dimensional scar assessment tool for keloid scars: Volume, erythema and melanin quantified.
Topics: Erythema; Humans; Keloid; Melanins | 2021 |
[Influence of connective tissue differentiation on scar tissue formation in children].
Topics: Child; Cicatrix, Hypertrophic; Collagen; Connective Tissue; Female; Fibroblasts; Humans; Keloid; Mal | 2021 |
Evaluating outcomes of pulsed dye laser therapy combined with intralesional triamcinolone injection after surgical removal of hypertrophic cesarean section scars.
Topics: Cesarean Section; Cicatrix, Hypertrophic; Female; Humans; Injections, Intralesional; Keloid; Lasers, | 2022 |
Individualized surgery combined with radiotherapy and triamcinolone acetonide injection for the treatment of auricular keloids.
Topics: Combined Modality Therapy; Humans; Keloid; Recurrence; Treatment Outcome; Triamcinolone Acetonide | 2021 |
[Research advances on the role and mechanism of inflammatory response in the formation of hypertrophic scars and keloids].
Topics: Cicatrix, Hypertrophic; Cytokines; Humans; Keloid; Quality of Life; Wound Healing | 2021 |
LINC01116 regulates proliferation, migration, and apoptosis of keloid fibroblasts by the TGF-β1/SMAD3 signaling via targeting miR-3141.
Topics: Adult; Animals; Apoptosis; Cell Line; Cell Movement; Cell Proliferation; Fibroblasts; Gene Expressio | 2021 |
Modified technique of intralesional radiofrequency with drug deposition in keloids using customized intravenous cannulas.
Topics: Cannula; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone Acetonide | 2023 |
A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.
Topics: Apoptosis; Caspase 9; Chemokine CXCL9; Chemotaxis; Computational Biology; Endothelial Cells; Gene Ex | 2022 |
[Curcumol inhibits keloid fibroblast proliferation and collagen synthesis through the ERK signaling pathway].
Topics: Apoptosis; Cell Proliferation; Collagen; Fibroblasts; Humans; Keloid; MAP Kinase Signaling System; S | 2021 |
Intralesional pentoxifylline, triamcinolone acetonide, and their combination for treatment of keloid scars.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Pentoxifylline; Treatment Outcome | 2021 |
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases.
Topics: Cell Adhesion Molecules; Collagen; Extracellular Matrix; Fibroblasts; Gene Expression Regulation; Ge | 2021 |
Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7.
Topics: Burns; Cell Proliferation; Collagen; Fibroblasts; Humans; Keloid; MicroRNAs; Smad7 Protein | 2021 |
A True Keloid in the Thorax.
Topics: Humans; Keloid; Thorax | 2021 |
Superficial X-ray-induced hyperpigmentation in postoperative keloid radiotherapy: A study of 70 keloids to identify clinical features and risk factors.
Topics: Humans; Hyperpigmentation; Keloid; Risk Factors; Treatment Outcome; X-Rays | 2021 |
Gazing Long into a Clinical and Social Abyss? Treating Hypertrophic Scarring and Keloids.
Topics: Cicatrix, Hypertrophic; COVID-19; Health Services Needs and Demand; Humans; Keloid; Pandemics | 2021 |
[Research advances on inflammatory responses involved in keloid development].
Topics: Humans; Inflammation; Inflammation Mediators; Keloid | 2021 |
Pressure therapy with a novel compressive device for auricular keloids treatment after surgical excision.
Topics: Adult; Aged; Combined Modality Therapy; Ear Auricle; Ear Deformities, Acquired; Equipment Design; Fe | 2021 |
Enhanced Drug Permeation into Human Keloid Tissues by Sonophoresis-Assisted Microneedling.
Topics: Humans; Keloid; Pain; Pharmaceutical Preparations; Treatment Outcome | 2021 |
Treatment of Keloid by Implantation of Tissue Expander beneath the Keloid Tissue.
Topics: China; Humans; Keloid; Recurrence; Retrospective Studies; Tissue Expansion Devices; Treatment Outcom | 2021 |
Single-Cell RNA-Sequencing Reveals Lineage-Specific Regulatory Changes of Fibroblasts and Vascular Endothelial Cells in Keloids.
Topics: Adult; Carcinogenesis; Cell Differentiation; Cell Lineage; Cells, Cultured; Endothelial Cells; Ephri | 2022 |
Systemic Fibrocyte Levels and Keloid Expression of the Chemoattractant CXCL12 Are Upregulated Compared With Patients With Normal Scar.
Topics: Cell Differentiation; Chemokine CXCL12; Chemotactic Factors; Cicatrix; Fibroblasts; Fibrosis; Humans | 2021 |
Exon skip-inducing variants in FLNA in an attenuated form of frontometaphyseal dysplasia.
Topics: Child; Cicatrix; Exons; Filamins; Forehead; Genes, X-Linked; Genetic Diseases, X-Linked; Genetic Pre | 2021 |
Surgical approach in the management of ear keloids: our experience with 30 patients.
Topics: Adolescent; Adult; Cryotherapy; Ear Auricle; Humans; Injections, Intralesional; Keloid; Middle Aged; | 2021 |
Evaluation of the Effects of Human Dental Pulp Stem Cells on the Biological Phenotype of Hypertrophic Keloid Fibroblasts.
Topics: Adult; Biological Assay; Cognition; Dental Pulp; Extracellular Matrix; Female; Fibroblasts; Humans; | 2021 |
Protein tyrosine phosphatase 1B regulates fibroblasts proliferation, motility and extracellular matrix synthesis via the MAPK/ERK signalling pathway in keloid.
Topics: Cell Proliferation; Cells, Cultured; Extracellular Matrix; Fibroblasts; Humans; Keloid; Protein Tyro | 2022 |
Modification of clip-on earring as pressure earring.
Topics: Ear, External; Humans; Keloid; Surgery, Plastic | 2023 |
Pinocembrin Ameliorates Skin Fibrosis via Inhibiting TGF-β1 Signaling Pathway.
Topics: Animals; Animals, Newborn; Cell Movement; Cell Proliferation; Female; Fibroblasts; Fibrosis; Flavano | 2021 |
Donor site morbidities resulting from conchal cartilage harvesting in rhinoplasty.
Topics: Adolescent; Adult; Aged; Female; Hematoma; Humans; Keloid; Male; Middle Aged; Nose Diseases; Postope | 2017 |
Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF-9/MAPK/Smad pathway.
Topics: Adolescent; Adult; Cell Movement; Cell Proliferation; Female; Fibroblasts; Growth Differentiation Fa | 2017 |
Effects of Photodynamic Therapy Using Yellow LED-light with Concomitant Hypocrellin B on Apoptotic Signaling in Keloid Fibroblasts.
Topics: Apoptosis; bcl-2-Associated X Protein; Fibroblasts; Keloid; Light; Perylene; Photochemotherapy; Prot | 2017 |
Advancing Keloid Treatment: A Novel Multimodal Approach to Ear Keloids.
Topics: Adolescent; Adult; Aged; Body Piercing; Combined Modality Therapy; Ear Auricle; Humans; Keloid; Midd | 2017 |
Identification of skin-related lncRNAs as potential biomarkers that involved in Wnt pathways in keloids.
Topics: Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Genetic Markers; Hu | 2017 |
Association of interleukin-6 gene polymorphisms and circulating levels with keloid scars in a Chinese Han population.
Topics: Adolescent; Adult; Alleles; Case-Control Studies; China; Female; Genotype; Humans; Interleukin-6; Ke | 2017 |
Morphological and morphometric analysis of the effects of intralesional tamoxifen on keloids.
Topics: Biopsy; Collagen; Female; Fibroblasts; Humans; Inflammation; Keloid; Male; Prospective Studies; Sele | 2017 |
Expansion of CD26 positive fibroblast population promotes keloid progression.
Topics: Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cytokines; Dipeptidyl Peptidase 4 | 2017 |
DKK3 regulates cell proliferation, apoptosis and collagen synthesis in keloid fibroblasts via TGF-β1/Smad signaling pathway.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Apoptosis; Cell Proliferation; Chemokines; | 2017 |
Histological analysis of hyalinised keloidal collagen formation in earlobe keloids over time: collagen hyalinisation starts in the perivascular area.
Topics: Adolescent; Adult; Collagen; Cross-Sectional Studies; Disease Progression; Ear, External; Female; Hu | 2017 |
Keloidal Scarring From the At-Home Use of Intense Pulsed Light for Tattoo Removal.
Topics: Humans; Intense Pulsed Light Therapy; Keloid; Male; Self Care; Skin Care; Tattooing; Young Adult | 2017 |
FDG-Avid Keloid on PET/CT Imaging.
Topics: Adult; Diagnosis, Differential; Fluorodeoxyglucose F18; Humans; Keloid; Male; Middle Aged; Positron | 2017 |
Effects of hTERT antisense oligodeoxynucleotide on cell apoptosis and expression of hTERT and bcl-2 mRNA in keloid fibroblasts.
Topics: Apoptosis; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Humans; Keloid; Oligodeoxyribon | 2017 |
A case-control study analyzing the association of keloids with hypertension and obesity.
Topics: Adult; Age Distribution; Black or African American; Case-Control Studies; Comorbidity; Female; Human | 2017 |
Adiponectin Is Involved in Connective Tissue Growth Factor-Induced Proliferation, Migration and Overproduction of the Extracellular Matrix in Keloid Fibroblasts.
Topics: Adiponectin; Adult; Cell Movement; Cell Proliferation; Cells, Cultured; Connective Tissue Growth Fac | 2017 |
Corneal keloid with cystoid cicatrix:post-small-incision cataract surgery.
Topics: Aged; Cataract Extraction; Conjunctiva; Cornea; Corneal Diseases; Cysts; Female; Humans; Keloid; Mic | 2017 |
miR-141-3p inhibits fibroblast proliferation and migration by targeting GAB1 in keloids.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Cycle; Cell Movement; Cell Proliferation; Cell | 2017 |
Noninvasive treatment of keloid using customized Re-188 skin patch.
Topics: Adult; Aged; Colloids; Female; Follow-Up Studies; Humans; Keloid; Male; Middle Aged; Radioisotopes; | 2017 |
In Situ Cytokine Expression and Morphometric Evaluation of Total Collagen and Collagens Type I and Type III in Keloid Scars.
Topics: Adolescent; Adult; Collagen; Collagen Type I; Collagen Type III; Cytokines; Female; Humans; Interfer | 2017 |
Lipo-PGE1 suppresses collagen production in human dermal fibroblasts via the ERK/Ets-1 signaling pathway.
Topics: Alprostadil; Blotting, Western; Cell Line; Collagen; Dermatologic Agents; Dermis; Fibroblasts; Flavo | 2017 |
[Umbilical endometriosis mimicking a keloid in a young black woman: A case report].
Topics: Abdominal Neoplasms; Adult; Black People; Diagnosis, Differential; Endometriosis; Female; Humans; Ke | 2017 |
Downregulation of β-catenin blocks fibrosis via Wnt2 signaling in human keloid fibroblasts.
Topics: Apoptosis; beta Catenin; Cell Proliferation; Cyclin D1; Female; Fibroblasts; Gene Expression Regulat | 2017 |
Inhibiting function of human fetal dermal mesenchymal stem cells on bioactivities of keloid fibroblasts.
Topics: Coculture Techniques; Dermis; Down-Regulation; Female; Fetus; Fibroblasts; Humans; Keloid; Male; Mes | 2017 |
Adjuvant irradiation to prevent keloidal fibroproliferative growth should be standard of care.
Topics: Adolescent; Adult; Aged; Cell Proliferation; Child; Child, Preschool; Dose-Response Relationship, Ra | 2017 |
The "Sandwich Therapy": A Microsurgical Integrated Approach for Presternal Keloid Treatment.
Topics: Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Humans; Keloid; Male; Middle Aged; | 2017 |
Abnormal expression of the vitamin D receptor in keloid scars.
Topics: Adolescent; Adult; Black People; Case-Control Studies; Cell Nucleus; Child; Child, Preschool; Epider | 2017 |
Microneedle physical contact as a therapeutic for abnormal scars.
Topics: Animals; Cells, Cultured; Child; Female; Humans; Keloid; Male; Polymers; Rabbits; Transdermal Patch | 2017 |
Treatment of ear keloids: algorithm for a multimodal therapy regimen.
Topics: Adult; Algorithms; Anti-Inflammatory Agents; Clinical Protocols; Combined Modality Therapy; Ear, Ext | 2017 |
Different properties of skin of different body sites: The root of keloid formation?
Topics: Aged; Aged, 80 and over; Cells, Cultured; Collagen Type I; Extracellular Matrix; Female; Fibroblasts | 2017 |
Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts.
Topics: Adult; Biopsy; Caveolin 1; Cell Movement; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Down | 2018 |
Identification of ASAH1 as a susceptibility gene for familial keloids.
Topics: Acid Ceramidase; Adult; Female; Humans; Keloid; Male; Mutation, Missense; Pedigree | 2017 |
Successful Treatment of Keloid With Fractionated Carbon Dioxide (CO2) Laser and Laser-Assisted Drug Delivery of Triamcinolone Acetonide Ointment in an African-American Man.
Topics: Administration, Cutaneous; Adult; Black or African American; Combined Modality Therapy; Drug Deliver | 2017 |
TMEM88 inhibits extracellular matrix expression in keloid fibroblasts.
Topics: Cell Movement; Cell Proliferation; Extracellular Matrix; Fibroblasts; Humans; Keloid; Membrane Prote | 2017 |
Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids.
Topics: Adenoviridae; Apoptosis; Cell Nucleus; Collagen Type I; Collagen Type III; Elastin; ErbB Receptors; | 2017 |
Intralesional excision with topical intralesional cryotherapy improves the treatment of keloid scarring in a paediatric patient.
Topics: Child; Cryotherapy; Ear, External; Female; Humans; Injections, Intralesional; Keloid | 2017 |
Pediatric keloids: A 6-year retrospective review.
Topics: Adolescent; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Keloid; Male; Nigeri | 2017 |
Pemphigus vulgaris complicated by extensive keloid scarring.
Topics: Anti-Inflammatory Agents; Female; Humans; Immunosuppressive Agents; Keloid; Middle Aged; Pemphigus; | 2018 |
Human adipose tissue-derived stem cells inhibit the activity of keloid fibroblasts and fibrosis in a keloid model by paracrine signaling.
Topics: Adipose Tissue; Adolescent; Adult; Apoptosis; Cell Movement; Cell Proliferation; Coculture Technique | 2018 |
Tumor suppressive role of miR-1224-5p in keloid proliferation, apoptosis and invasion via the TGF-β1/Smad3 signaling pathway.
Topics: Adult; Apoptosis; Cell Proliferation; Female; Genes, Tumor Suppressor; Humans; Keloid; Male; MicroRN | 2018 |
Role of Homeodomain-Interacting Protein Kinase 2 in the Pathogenesis of Tissue Fibrosis in Keloid-Derived Keratinocytes.
Topics: Carrier Proteins; Cells, Cultured; Epithelial-Mesenchymal Transition; Gene Expression Regulation; Hu | 2017 |
[Advances in the research of treatment of angiogenesis inhibitor on pathological scars].
Topics: Angiogenesis Inhibitors; Cicatrix, Hypertrophic; Collagen; Fibroblasts; Humans; Keloid; Neovasculari | 2017 |
A novel model of humanised keloid scarring in mice.
Topics: Animals; Cell Proliferation; Cells, Cultured; China; Fibroblasts; Humans; Keloid; Mice; Mice, Nude; | 2018 |
Complete excision of proliferating core in auricular keloids significantly reduces local recurrence: A prospective study.
Topics: Adolescent; Adult; Asian People; Dermatologic Surgical Procedures; Ear, External; Female; Fibroblast | 2018 |
Up-regulation of α
Topics: Adult; Blood Vessels; Burns; Cicatrix; Dermis; Female; Fibroblasts; Humans; Immunohistochemistry; Ke | 2018 |
Bilateral breast keloids in an elderly woman associated with bilateral breast cancers and high concentration of serum tumor growth factor-β.
Topics: Aged; Breast Neoplasms; Female; Humans; Keloid; Lymphotoxin-alpha; Skin | 2017 |
A simple device for ablation of keloidal tissue and serial deposition of intralesional drugs.
Topics: Ablation Techniques; Dermatologic Agents; Fluorouracil; Humans; Injections, Intralesional; Keloid; T | 2018 |
Decoy Wnt receptor (sLRP6E1E2)-expressing adenovirus induces anti-fibrotic effect via inhibition of Wnt and TGF-β signaling.
Topics: Adenoviridae; beta Catenin; Cells, Cultured; Collagen Type I; Collagen Type III; Dermis; Extracellul | 2017 |
Three-dimensional poly lactic-co-glycolic acid scaffold containing autologous platelet-rich plasma supports keloid fibroblast growth and contributes to keloid formation in a nude mouse model.
Topics: Adult; Animals; Cells, Cultured; Collagen; Disease Models, Animal; Female; Fibroblasts; Genetic Vect | 2018 |
[Not Available].
Topics: Adolescent; Adult; Child; Ear, External; Esthetics; Female; Follow-Up Studies; Granuloma, Foreign-Bo | 2017 |
Opposite effects of non-thermal plasma on cell migration and collagen production in keloid and normal fibroblasts.
Topics: Adult; Cell Movement; Collagen; Female; Fibroblasts; Humans; Keloid; Male; Plasma Gases; Proteins | 2017 |
Could -79 °C Spray-Type Cryotherapy Be an Effective Monotherapy for the Treatment of Keloid?
Topics: Adolescent; Adult; Cells, Cultured; Cryotherapy; Female; Fibroblasts; Humans; Keloid; Matrix Metallo | 2017 |
Characterization of CD45RO
Topics: Antigens, CD; Case-Control Studies; CD8-Positive T-Lymphocytes; Cicatrix; Humans; Immunologic Memory | 2018 |
Pertinence d'une excroissance à l'ombilic en gynécologie.
Topics: Endometriosis; Female; Humans; Keloid; Sister Mary Joseph's Nodule; Umbilicus | 2017 |
Keloid-like reaction to cocaine use.
Topics: Administration, Topical; Adult; Cocaine; Cocaine-Related Disorders; Humans; Keloid; Male; Penile Dis | 2019 |
DNA methylation of the CDC2L1 gene promoter region decreases the expression of the CDK11p58 protein and reduces apoptosis in keloid fibroblasts.
Topics: Adolescent; Adult; Apoptosis; Azacitidine; CpG Islands; Cyclin-Dependent Kinases; DNA Methylation; D | 2018 |
Optimizing Radiotherapy for Keloids: A Meta-Analysis Systematic Review Comparing Recurrence Rates Between Different Radiation Modalities.
Topics: Ear, External; Humans; Keloid; Radiotherapy Dosage; Radiotherapy, Adjuvant; Recurrence | 2018 |
Endothelial dysfunction may promote keloid growth.
Topics: Adolescent; Adult; Age of Onset; Aged; Case-Control Studies; Comorbidity; Cross-Sectional Studies; E | 2017 |
Insights into the Pathophysiology of Hypertrophic Scars and Keloids: How Do They Differ?
Topics: Biopsy, Needle; Cicatrix, Hypertrophic; Female; Humans; Immunohistochemistry; Keloid; Male; Risk Ass | 2018 |
A melanotic malignant melanoma presenting as a keloid: A case report.
Topics: Diagnosis, Differential; Female; Humans; Keloid; Melanoma, Amelanotic; Shoulder; Skin Neoplasms; You | 2017 |
Optimal High-Dose-Rate Brachytherapy Fractionation Scheme After Keloid Excision: A Retrospective Multicenter Comparison of Recurrence Rates and Complications.
Topics: Adult; Brachytherapy; Dose Fractionation, Radiation; Female; Humans; Iridium Radioisotopes; Keloid; | 2018 |
Macrophages in keloid are potent at promoting the differentiation and function of regulatory T cells.
Topics: Adult; Cell Differentiation; Female; Forkhead Transcription Factors; Humans; Interleukin-10; Keloid; | 2018 |
Pediatric dermatology procedures and pearls: Multimodal revision of earlobe keloids.
Topics: Combined Modality Therapy; Dermatology; Ear Diseases; Ear, External; Glucocorticoids; Humans; Keloid | 2018 |
Identification of the potential targets for keloid and hypertrophic scar prevention.
Topics: Cicatrix, Hypertrophic; Databases, Genetic; Down-Regulation; Humans; Keloid; Protein Interaction Map | 2018 |
High-Mobility Group Box 1 Mediates Fibroblast Activity via RAGE-MAPK and NF-κB Signaling in Keloid Scar Formation.
Topics: Anti-Inflammatory Agents; Antigens, Neoplasm; Biological Assay; Cell Movement; Cell Tracking; Fibrob | 2017 |
Knockdown of elF3a inhibits TGF‑β1‑induced extracellular matrix protein expression in keloid fibroblasts.
Topics: Actins; Cell Proliferation; Collagen Type I; Eukaryotic Initiation Factor-3; Extracellular Matrix; F | 2018 |
Autografting in the treatment of large, auricular keloids.
Topics: Adult; Aged; Autografts; Ear Auricle; Female; Humans; Keloid; Male; Skin Transplantation; Transplant | 2018 |
Commentary on The Cellular Response of Keloids and Hypertrophic Scars to Botulinum Toxin A: A Comprehensive Literature Review.
Topics: Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Humans; Keloid | 2018 |
Near-Infrared Fluorescent Molecular Probe for Sensitive Imaging of Keloid.
Topics: Cell Line; Endopeptidases; Fluorescent Dyes; Gelatinases; Humans; In Vitro Techniques; Keloid; Membr | 2018 |
Optimizing Radiotherapy for Keloids.
Topics: Ear, External; Humans; Keloid; Radiotherapy Dosage; Recurrence | 2018 |
Ginsenoside Rg3 inhibits keloid fibroblast proliferation, angiogenesis and collagen synthesis in vitro via the TGF‑β/Smad and ERK signaling pathways.
Topics: Adult; Apoptosis; Cell Movement; Cell Proliferation; Collagen; Extracellular Matrix; Female; Fibrobl | 2018 |
Metabolic reprogramming in keloid fibroblasts: Aerobic glycolysis and a novel therapeutic strategy.
Topics: Cell Proliferation; Cells, Cultured; Deoxyglucose; Fibroblasts; Gene Expression Regulation; Glucose; | 2018 |
Aesthetic reconstruction of retroauricular keloid: Creating a keystone flap from the mastoid-helix area.
Topics: Adult; Cartilage; Ear Auricle; Esthetics; Female; Follow-Up Studies; Humans; Keloid; Male; Mastoid; | 2018 |
Conditioned Medium Obtained from Amnion-Derived Mesenchymal Stem Cell Culture Prevents Activation of Keloid Fibroblasts.
Topics: Actins; Administration, Cutaneous; Adolescent; Adult; Amnion; Cell Proliferation; Cell- and Tissue-B | 2018 |
Delayed diagnosis of dermal leiomyosarcoma mimicking keloid scar.
Topics: Adult; Cicatrix; Delayed Diagnosis; Diagnosis, Differential; Humans; Keloid; Leiomyoma; Leiomyosarco | 2018 |
The Effects of Postoperative Intralesional Corticosteroids in the Prevention of Recurrent Earlobe Keloids: A Multispecialty Retrospective Review.
Topics: Adolescent; Adult; Child; Ear, External; Female; Follow-Up Studies; Glucocorticoids; Humans; Injecti | 2018 |
Toe keloid after nail extraction treated with surgical excision: A case report.
Topics: Humans; Keloid; Male; Paronychia; Postoperative Complications; Skin Transplantation; Toes; Young Adu | 2017 |
High temperature requirement factor A1 (HTRA1) regulates the activation of latent TGF-β1 in keloid fibroblasts.
Topics: Cells, Cultured; Fibroblasts; High-Temperature Requirement A Serine Peptidase 1; Humans; Keloid; RNA | 2018 |
A Rare Case of Misdiagnosis: Recurrence of Dermatofibrosarcoma Protuberans That Was Treated Surgicallyas a Keloid.
Topics: Adult; Dermatofibrosarcoma; Diagnostic Errors; Female; Humans; Keloid; Neoplasm Recurrence, Local; R | 2018 |
What is your diagnosis? Subcutaneous mass on a dog.
Topics: Adipose Tissue; Animals; Diagnosis, Differential; Dog Diseases; Dogs; Fibrosarcoma; Keloid; Male; Su | 2018 |
Methylation of secreted frizzled-related protein 1 (SFRP1) promoter downregulates Wnt/β-catenin activity in keloids.
Topics: beta Catenin; DNA Methylation; Down-Regulation; Fibroblasts; Humans; Intracellular Signaling Peptide | 2018 |
Human adipose-derived stem cells inhibit bioactivity of keloid fibroblasts.
Topics: Adipose Tissue; Culture Media, Conditioned; Extracellular Matrix; Female; Fibroblasts; Gene Expressi | 2018 |
Human adipose-derived stem cells inhibit bioactivity of keloid fibroblasts.
Topics: Adipose Tissue; Culture Media, Conditioned; Extracellular Matrix; Female; Fibroblasts; Gene Expressi | 2018 |
Human adipose-derived stem cells inhibit bioactivity of keloid fibroblasts.
Topics: Adipose Tissue; Culture Media, Conditioned; Extracellular Matrix; Female; Fibroblasts; Gene Expressi | 2018 |
Human adipose-derived stem cells inhibit bioactivity of keloid fibroblasts.
Topics: Adipose Tissue; Culture Media, Conditioned; Extracellular Matrix; Female; Fibroblasts; Gene Expressi | 2018 |
Coexistence of keloids and pilomatricoma in a patient with Rubinstein-Taybi syndrome.
Topics: Adult; beta Catenin; Cyclic AMP Response Element-Binding Protein; Humans; Keloid; Male; Pilomatrixom | 2018 |
Gene-based evaluation of low-frequency variation and genetically-predicted gene expression impacting risk of keloid formation.
Topics: Adult; Aged; Black or African American; Case-Control Studies; Exome; Female; Gene Flow; Genetic Asso | 2018 |
Characterization of In Vitro Reconstructed Human Normotrophic, Hypertrophic, and Keloid Scar Models.
Topics: Adolescent; Adult; Aged; Biomarkers; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chil | 2018 |
The mechanisms of β-catenin on keloid fibroblast cells proliferation and apoptosis.
Topics: Adolescent; Adult; Apoptosis; beta Catenin; Caspase 3; Cell Proliferation; Fibroblasts; Gene Knockdo | 2018 |
MiR-21 regulates the apoptosis of keloid fibroblasts by caspase-8 and the mitochondria-mediated apoptotic signaling pathway via targeting FasL.
Topics: Apoptosis; Caspase 8; Fas Ligand Protein; Female; Fibroblasts; Humans; Keloid; Male; MicroRNAs; Mito | 2018 |
miR-34 modulates apoptotic gene expression in Ingenol mebutate treated keloid fibroblasts.
Topics: Apoptosis; Cells, Cultured; Diterpenes; DNA Fragmentation; Fibroblasts; Gene Expression Regulation; | 2018 |
Cells to Surgery Quiz: April 2018.
Topics: Dermatologic Surgical Procedures; Dermis; Diagnosis, Differential; Drug Therapy, Combination; Fibrob | 2018 |
Angiomatoid and desmoplastic Spitz nevus presenting as a keloidal nodule.
Topics: Adolescent; Diagnosis, Differential; Humans; Keloid; Male; Nevus, Epithelioid and Spindle Cell; Skin | 2018 |
Centella asiatica (Centellicum®) facilitates the regular healing of surgical scars in subjects at high risk of keloids.
Topics: Abdomen; Antibiotic Prophylaxis; Centella; Cicatrix; Cicatrix, Hypertrophic; Collagen; Drug Evaluati | 2018 |
Treatment of auricular keloids by triple combination therapy: Surgical excision, platelet-rich plasma, and cryosurgery.
Topics: Adolescent; Adult; Child; Combined Modality Therapy; Cryosurgery; Dermatologic Surgical Procedures; | 2018 |
Further evidence for T-cell involvement in the pathogenesis of keloids.
Topics: Fibroblasts; Humans; Keloid; T-Lymphocytes | 2018 |
Tissue stiffening promotes keratinocyte proliferation through activation of epidermal growth factor signaling.
Topics: Biomechanical Phenomena; Cell Proliferation; Epidermal Growth Factor; Epidermis; Extracellular Matri | 2018 |
The fortune cookie flap for aesthetic reconstruction after chest keloid resection: a small case series.
Topics: Adult; Female; Humans; Keloid; Male; Middle Aged; Plastic Surgery Procedures; Recurrence; Reproducib | 2018 |
HtrA1 Is Specifically Up-Regulated in Active Keloid Lesions and Stimulates Keloid Development.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Biopsy; Cell Proliferation; Cells, Cultured; | 2018 |
Evaluating the Therapeutic Success of Keloids Treated With Cryotherapy and Intralesional Corticosteroids Using Noninvasive Objective Measures.
Topics: Adolescent; Adult; Cryotherapy; Female; Glucocorticoids; Humans; Imaging, Three-Dimensional; Injecti | 2018 |
Lobomycosis: a therapeutic challenge.
Topics: Adult; Antifungal Agents; Biopsy; Clofazimine; Cryotherapy; Diagnosis, Differential; Ear Diseases; H | 2018 |
Use of neodymium magnetic discs as pressure earrings for earlobe keloid postexcision.
Topics: Ear, External; Humans; Iron; Keloid; Magnets; Neodymium; Postoperative Care; Pressure; Secondary Pre | 2019 |
Combination therapy for bulky auricular keloids: a clinical experience.
Topics: Adult; Combined Modality Therapy; Ear, External; Female; Humans; Keloid; Male; Middle Aged | 2019 |
Histoid Leprosy Presenting with Keloid Like Lesions.
Topics: Adult; Histology; Humans; Keloid; Leprosy; Male; Mycobacterium leprae; Skin | 2016 |
[ESTABLISHING AN ANIMAL MODEL OF DEFECATION RECONSTRUCTION AFTER SPINAL CORD INJURY IN RATS BY MECHANICAL POLISHING METHOD].
Topics: Animals; Cauda Equina; Defecation; Disease Models, Animal; Epidermis; Female; Humans; Immunohistoche | 2016 |
[Comparative study of surgical treatment combined with various methods for treatment of ear scar].
Topics: Adrenal Cortex Hormones; Combined Modality Therapy; Glucocorticoids; Humans; Injections; Injections, | 2017 |
Novel Stereoscopic Optical System for Objectively Measuring Above-Surface Scar Volume-First-Time Quantification of Responses to Various Treatment Modalities.
Topics: Adult; Cicatrix, Hypertrophic; Cryosurgery; Dermatologic Agents; Feasibility Studies; Female; Fluoro | 2018 |
Upregulation of autophagy and glycolysis markers in keloid hypoxic-zone fibroblasts: Morphological characteristics and implications.
Topics: Autophagy; Autophagy-Related Proteins; Biomarkers; Cell Hypoxia; Fibroblasts; Fluorescent Antibody T | 2018 |
Downregulation of miR‑637 promotes proliferation and metastasis by targeting Smad3 in keloids.
Topics: Adult; Base Sequence; Case-Control Studies; Cell Movement; Cell Proliferation; Female; Fibroblasts; | 2018 |
Calcimycin Suppresses S100A4 Expression and Inhibits the Stimulatory Effect of Transforming Growth Factor β1 on Keloid Fibroblasts.
Topics: Adolescent; Adult; Aged; Biomarkers; Blotting, Western; Calcimycin; Calcium Ionophores; Case-Control | 2018 |
Profibrogenic effect of high-mobility group box protein-1 in human dermal fibroblasts and its excess in keloid tissues.
Topics: Fibroblasts; Gene Expression Regulation, Enzymologic; HMGB1 Protein; Humans; Intracellular Space; Ke | 2018 |
Gene expression profiling analysis: the effect of hydrocortisone on keloid fibroblasts by bioinformatics.
Topics: Cluster Analysis; Computational Biology; Fibroblasts; Gene Expression Profiling; Humans; Hydrocortis | 2019 |
Time Series Integrative Analysis of RNA Sequencing and MicroRNA Expression Data Reveals Key Biologic Wound Healing Pathways in Keloid-Prone Individuals.
Topics: Adult; Disease Susceptibility; Female; Humans; Keloid; Male; MAP Kinase Signaling System; MicroRNAs; | 2018 |
Recent Advances in Scar Biology.
Topics: Animals; Cicatrix; Humans; Keloid; Wound Healing | 2018 |
Efficacy of lentivirus‑mediated Drosophila melanogaster deoxyribonucleoside kinase combined with (E)‑5‑(2‑bromovinyl)‑2'‑deoxyuridine or 1‑β‑D‑arabinofuranosylthymine therapy in human keloid fibroblasts.
Topics: Adult; Animals; Apoptosis; Arabinonucleosides; Bromodeoxyuridine; Bystander Effect; Cell Proliferati | 2018 |
Clinical outcomes of totally implantable venous access port placement via the axillary vein in patients with head and neck malignancy.
Topics: Adult; Aged; Aged, 80 and over; Axillary Vein; Catheter Obstruction; Catheter-Related Infections; Ca | 2019 |
Vitiligo at a keloid scar: A possible case of Koebner phenomenon.
Topics: Humans; Keloid; Male; Middle Aged; Skin; Thoracic Wall; Vitiligo | 2019 |
Identification of a novel mutation in the mechanoreceptor-encoding gene CXCR1 in patients with keloid.
Topics: China; Cicatrix, Hypertrophic; Female; Genetic Testing; Humans; Immunohistochemistry; Keloid; Male; | 2018 |
Comparative efficacy of intralesional triamcinolone acetonide injection during early and static stage of pathological scarring.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Glucocorticoids; H | 2019 |
A retrospective analysis of surgical resection of large ear keloids.
Topics: Adult; Body Piercing; Combined Modality Therapy; Dermatologic Surgical Procedures; Ear Diseases; Ear | 2019 |
Dose Effect in Adjuvant Radiation Therapy for the Treatment of Resected Keloids.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Radiation; Female; Humans; K | 2018 |
Keloid formation after syndactyly release in a patient with macrodactyly - methotrexate treatment.
Topics: Administration, Oral; Child, Preschool; Dermatologic Agents; Female; Fingers; Humans; Keloid; Limb D | 2019 |
Treatment of keloid-scar under polarized dermoscopy.
Topics: Cicatrix, Hypertrophic; Dermoscopy; Humans; Keloid | 2021 |
Keloid risk in patients with atopic dermatitis: a nationwide retrospective cohort study in Taiwan.
Topics: Adult; Cohort Studies; Dermatitis, Atopic; Female; Humans; Incidence; Keloid; Male; Middle Aged; Mul | 2018 |
[Different effects of simvastatin on keloid fibroblasts under hypoxia and TGF-β1 treatment].
Topics: Apoptosis; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Collagen Type I; Connective Tissue Gro | 2016 |
Identification and integrated analysis of microRNA expression profiles in keloid.
Topics: Adult; China; Down-Regulation; Female; Gene Expression Regulation; Genomics; Humans; Keloid; Male; M | 2018 |
[In vitro study of effects and mechanism of rapamycin-induced autophagy in keloid fibroblasts].
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Collagen Type I; Fibroblasts; Fibronecti | 2016 |
[Use of fan-shaped scar flap for reconstruction after auricular keloid core excision: an analysis of 193 lesions in 177 patients].
Topics: Adrenal Cortex Hormones; Ear Auricle; Ear, External; Humans; Injections, Intralesional; Keloid; Plas | 2016 |
Plasma Angiotensin-converting Enzyme Levels in Patients With Keloids and/or Hypertension.
Topics: Adolescent; Adult; Aged; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypertension; Keloid; Ma | 2018 |
[Mitochondrial dysfunctions of keloid fibroblasts and it' s effects on cell metabolic functions].
Topics: Cell Proliferation; Cells, Cultured; Fibroblasts; Gene Expression; GTP Phosphohydrolases; Humans; Ke | 2016 |
[Calidad de vida en adultos con cicatrices queloides].
Topics: Adult; Cross-Sectional Studies; Depression; Female; Humans; Keloid; Male; Quality of Life; Self Repo | 2018 |
[The effects of down-regulated ITGB5 expression on the proliferation of keloid fibroblasts].
Topics: Cell Proliferation; Cells, Cultured; Down-Regulation; Fibroblasts; Humans; Integrin beta Chains; Kel | 2017 |
[The application of iTRAQ quantitative proteomics in familial keloid].
Topics: Biomarkers; Blotting, Western; Cicatrix; Cicatrix, Hypertrophic; Computational Biology; Down-Regulat | 2017 |
The lived experience and quality of life with burn scarring-The results from a large-scale online survey.
Topics: Adaptation, Psychological; Adolescent; Adult; Aftercare; Anxiety; Burns; Cicatrix; Cicatrix, Hypertr | 2018 |
Prevention of Earlobe Keloid Recurrence After Excision: Assessment of the Value of Presurgical Injection of Triamcinolone.
Topics: Ear, External; Female; Follow-Up Studies; Glucocorticoids; Humans; Keloid; Male; Preoperative Care; | 2018 |
Efficacy of Autologous Platelet Concentrates as Adjuvant Therapy to Surgical Excision in the Treatment of Keloid Scars Refractory to Conventional Treatments: A Pilot Prospective Study.
Topics: Combined Modality Therapy; Humans; Keloid; Pilot Projects; Prospective Studies | 2018 |
Aesthetic reconstruction of extensive pubic keloids using bilateral modified keystone flaps.
Topics: Abdomen; Adult; Dermatologic Surgical Procedures; Esthetics; Female; Humans; Keloid; Perineum; Plast | 2019 |
[Effectiveness of internal mammary artery perforator propeller flap repair combined with radiotherapy for chest keloid in female patients].
Topics: Adult; Aged; Female; Humans; Keloid; Mammary Arteries; Middle Aged; Perforator Flap; Plastic Surgery | 2018 |
Exuberant keloid scar associated with skin neoplasia.
Topics: Aged; Biopsy; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cicatrix, Hypertrophic; Humans; Keloi | 2018 |
Hypopigmentation on the ear.
Topics: Adrenal Cortex Hormones; Diagnosis, Differential; Ear Diseases; Female; Humans; Hypopigmentation; In | 2018 |
High in situ mRNA levels of IL-22, TFG-β, and ARG-1 in keloid scars.
Topics: Adult; Arginase; Biomarkers; Biopsy; Case-Control Studies; Female; Gene Expression; Humans; In Situ | 2018 |
Management of epidermal cysts arising from scar tissues: A retrospective clinical study.
Topics: Adult; Cicatrix, Hypertrophic; Epidermal Cyst; Female; Humans; Keloid; Laser Therapy; Male; Middle A | 2018 |
[PREFACE TO “WOUND CLOSURE METHODS FOR PREVENTION OF SURGICAL SITE INFECTION AND PATHOLOGIC SCARS ― INCISION AND SUTURE METHODS FOR PREVENTION OF SSI, HYPERTROPHIC SCARS AND KELOID ―”].
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Surgical Wound; Surgical Wound Infection; Suture Techniques; | 2017 |
[WOUND CLOSURE METHODS FOR PREVENTION OF SURGICAL SITE INFECTION AND PATHOLOGIC SCARS－INCISION AND SUTURE METHODS FOR PREVENTION OF SSI, HYPERTROPHIC SCARS AND KELOID-].
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Surgical Wound; Surgical Wound Infection; Suture Techniques; | 2017 |
Keloid formation after pediatric male genital surgeries: an uncommon and difficult problem to manage.
Topics: Child; Child, Preschool; Genitalia, Male; Humans; Infant; Keloid; Male; Postoperative Complications; | 2019 |
Wnt2 knock down by RNAi inhibits the proliferation of in vitro-cultured human keloid fibroblasts.
Topics: Adolescent; Adult; Blotting, Western; Child; Child, Preschool; Cyclin D1; Female; Fibroblasts; Glyco | 2018 |
Gallic acid inhibits fibroblast growth and migration in keloids through the AKT/ERK signaling pathway.
Topics: Adult; Apoptosis; Cell Cycle; Cell Movement; Cell Proliferation; Cells, Cultured; Extracellular Sign | 2018 |
NEDD4 Is Involved in Inflammation Development during Keloid Formation.
Topics: Adult; Aged; Alleles; Biomarkers; Cell Line; Child; Female; Fibroblasts; Gene Knockdown Techniques; | 2019 |
Extensive CD34-to-CD90 Fibroblast Transition Defines Regions of Cutaneous Reparative, Hypertrophic, and Keloidal Scarring.
Topics: Actins; Antigens, CD34; Biomarkers; Cicatrix, Hypertrophic; Collagen Type I; Fibroblasts; Fibrosis; | 2019 |
Pelvic reactive lymphadenopathy mimicking lymph node metastasis of heel malignant melanoma.
Topics: Diagnosis, Differential; Heel; Humans; Keloid; Lymphadenopathy; Lymphatic Metastasis; Male; Melanoma | 2018 |
Gene Expression of Neurotrophins and Their Receptors in Keloids.
Topics: Adolescent; Adult; Brazil; Cross-Sectional Studies; Gene Expression; Humans; Keloid; Middle Aged; Ne | 2018 |
Bold to do - bald to be? Outcomes decades after harvesting the scalp in burned children.
Topics: Adolescent; Adult; Alopecia; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Follow- | 2019 |
Increased Cthrc1 Activates Normal Fibroblasts and Suppresses Keloid Fibroblasts by Inhibiting TGF-β/Smad Signal Pathway and Modulating YAP Subcellular Location.
Topics: Adaptor Proteins, Signal Transducing; Adventitia; Extracellular Matrix Proteins; Fibroblasts; Gene E | 2018 |
Posterior Earlobe Mass.
Topics: Ear; Humans; Keloid; Male; Young Adult | 2018 |
Adipose-derived mesenchymal stem cells treatments for fibroblasts of fibrotic scar via downregulating TGF-β1 and Notch-1 expression enhanced by photobiomodulation therapy.
Topics: Actins; Adipose Tissue; Animals; Apoptosis; Cell Movement; Cell Proliferation; Cicatrix, Hypertrophi | 2019 |
Efficacy of 5-aminolevulinic acid-based photodynamic therapy against keloid compromised by downregulation of SIRT1-SIRT3-SOD2-mROS dependent autophagy pathway.
Topics: Aminolevulinic Acid; Apoptosis; Autophagy; Fibroblasts; Humans; Keloid; Levulinic Acids; Light; Oxid | 2019 |
Reconstructed human keloid models show heterogeneity within keloid scars.
Topics: Cell Proliferation; Chemokine CCL20; Chemokine CCL27; Child; Child, Preschool; Cicatrix, Hypertrophi | 2018 |
MiR-203 regulates keloid fibroblast proliferation, invasion, and extracellular matrix expression by targeting EGR1 and FGF2.
Topics: 3' Untranslated Regions; Adult; Cell Proliferation; Cells, Cultured; Early Growth Response Protein 1 | 2018 |
A parasternal intercostal perforator flap for esthetic reconstruction after complete chest keloid resection: A retrospective observational cohort study.
Topics: Adult; Aged; China; Female; Humans; Keloid; Male; Middle Aged; Perforator Flap; Plastic Surgery Proc | 2018 |
Development of Individualized Induced Pluripotent Stem Cells From Fibroblasts of Keloid Lesions in Patients.
Topics: Animals; Cell Differentiation; Cells, Cultured; Cellular Reprogramming Techniques; Fibroblasts; Huma | 2018 |
Combined Non-Ablative Laser and Microfat Grafting for Burn Scar Treatment.
Topics: Adipose Tissue; Adolescent; Adult; Burns; Child; Child, Preschool; Cicatrix; Cicatrix, Hypertrophic; | 2019 |
Sensory perception and nerve fibre innervation in patients with keloid scars: an investigative study.
Topics: Biopsy; Humans; Hyperalgesia; Keloid; Nerve Fibers; Neuralgia; Pain; Pain Measurement; Skin | 2018 |
Keloid negatively affects body image.
Topics: Adult; Body Dissatisfaction; Body Dysmorphic Disorders; Body Image; Ear; Face; Female; Humans; Keloi | 2019 |
Adjuvant Radiotherapy After Keloid Excision: Preliminary Experience in Taiwan.
Topics: Adult; Databases, Factual; Dermatologic Surgical Procedures; Esthetics; Feasibility Studies; Female; | 2019 |
Two Cases of Granular Cell Tumors that Clinically Mimicked Hypertrophic Scars and Keloids.
Topics: Aged, 80 and over; Cicatrix, Hypertrophic; Diagnosis, Differential; Female; Granular Cell Tumor; Hum | 2018 |
Two Cases of Sclerotic Fibroma of the Skin that Mimicked Keloids Clinically.
Topics: Adult; Diagnosis, Differential; Fibroma; Humans; Keloid; Leg; Male; Middle Aged; Shoulder; Skin Neop | 2018 |
Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair.
Topics: Adipocytes; Animals; Cell Proliferation; Extracellular Matrix; Fibrosis; Integrin beta1; Keloid; Lec | 2018 |
A Role for the E3 Ubiquitin Ligase NEDD4 in Keloid Pathogenesis.
Topics: Endosomal Sorting Complexes Required for Transport; Humans; Inflammation; Keloid; Nedd4 Ubiquitin Pr | 2019 |
A thermosensitive RGD-modified hydroxybutyl chitosan hydrogel as a 3D scaffold for BMSCs culture on keloid treatment.
Topics: Biocompatible Materials; Chitosan; Fibroblasts; Hemolysis; Humans; Hydrogels; Keloid; Materials Test | 2019 |
Analysis of Keloid Response to 5-Fluorouracil Treatment and Long-Term Prevention of Keloid Recurrence.
Topics: Adaptor Proteins, Signal Transducing; Biopsy; Chemokine CCL2; Dermis; Fluorouracil; Follow-Up Studie | 2019 |
Detection and Analysis of the Hedgehog Signaling Pathway-Related Long Non-Coding RNA (lncRNA) Expression Profiles in Keloid.
Topics: Adult; Female; Gene Expression; Gene Expression Profiling; Gene Ontology; Hedgehog Proteins; Humans; | 2018 |
In vitro analysis of the role of tumor necrosis factor‑stimulated gene‑6 in keloid.
Topics: Adolescent; Adult; Apoptosis; Cell Adhesion Molecules; Cell Cycle Checkpoints; Cell Proliferation; C | 2019 |
Intralesional Steroids and Compression Devices for Keloids.
Topics: Adolescent; Adult; Combined Modality Therapy; Compression Bandages; Ear, External; Female; Humans; I | 2019 |
Tension enhances cell proliferation and collagen synthesis by upregulating expressions of integrin αvβ3 in human keloid-derived mesenchymal stem cells.
Topics: Adolescent; Adult; Blotting, Western; Cell Proliferation; Collagen; Female; Flow Cytometry; Gene Exp | 2019 |
Treatment of Keloid Scars with Botulinum Toxin Type A versus Triamcinolone in an Athymic Nude Mouse Model.
Topics: Acetylcholine Release Inhibitors; Adult; Animals; Botulinum Toxins, Type A; Disease Models, Animal; | 2019 |
Integrated Interaction Network of MicroRNA Target Genes in Keloid Scarring.
Topics: Apoptosis; Cicatrix; Extracellular Matrix; Humans; Keloid; MicroRNAs; Molecular Targeted Therapy; On | 2019 |
MicroRNA-152-5p inhibits proliferation and migration and promotes apoptosis by regulating expression of Smad3 in human keloid fibroblasts.
Topics: Adolescent; Adult; Apoptosis; Cell Proliferation; Down-Regulation; Female; Fibroblasts; Humans; Kelo | 2019 |
Combined Therapeutic Strategies for Keloid Treatment.
Topics: Combined Modality Therapy; Cryotherapy; Dose Fractionation, Radiation; Female; Glucocorticoids; Huma | 2019 |
Targeting mTORC1/2 with OSI-027 inhibits proliferation and migration of keloid keratinocytes.
Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Fibrob | 2019 |
Reply to comments on "comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial".
Topics: Burns; Cicatrix, Hypertrophic; Fluorouracil; Humans; Injections, Intralesional; Keloid; Triamcinolon | 2020 |
miR-188-5p regulates proliferation and invasion via PI3K/Akt/MMP-2/9 signaling in keloids.
Topics: Adolescent; Adult; Cell Movement; Cell Proliferation; Cells, Cultured; Female; Gene Expression Profi | 2019 |
Fractionated devolumizing keloid tissue: The 'pop' method: A novel technique to facilitate administration of intralesional corticosteroid in difficult keloids.
Topics: Adrenal Cortex Hormones; Humans; Injections, Intralesional; Keloid; Treatment Outcome | 2023 |
Aligned topography mediated cell elongation reverses pathological phenotype of in vitro cultured keloid fibroblasts.
Topics: Adolescent; Adult; Aged; Cell Cycle Checkpoints; Cell Proliferation; Cells, Cultured; Child; Extrace | 2019 |
Multi-dimensional models for functional testing of keloid scars: In silico, in vitro, organoid, organotypic, ex vivo organ culture, and in vivo models.
Topics: Animals; Computer Simulation; Fibroblasts; Humans; Keloid; Models, Biological; Molecular Targeted Th | 2019 |
Oncostatin M exerts a protective effect against excessive scarring by counteracting the inductive effect of TGFβ1 on fibrosis markers.
Topics: Adult; Biomarkers; Case-Control Studies; Cicatrix, Hypertrophic; Female; Fibroblasts; Fibrosis; Foll | 2019 |
Efficacy of fractional CO
Topics: Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Glucocorticoids; Humans; Injection | 2019 |
In Reply to Roos and Smith.
Topics: Humans; Keloid; Radiotherapy, Adjuvant | 2019 |
In Regard to Renz et al.
Topics: Humans; Keloid; Radiotherapy, Adjuvant | 2019 |
Galectin-1 and Galectin-3 and Their Potential Binding Partners in the Dermal Thickening of Keloid Tissues.
Topics: Adolescent; Adult; Biomarkers; Blood Proteins; Dermis; Female; Fibroblasts; Galectin 1; Galectin 3; | 2019 |
Chondrocutaneous Bilateral Advancement Flap with Postoperative Radiation Therapy for a Helical Rim Keloid.
Topics: Adolescent; Adult; Combined Modality Therapy; Dermatologic Surgical Procedures; Ear Auricle; Ear Car | 2019 |
A multimodal therapeutic approach improves the clinical outcome of auricular keloid patients.
Topics: Adolescent; Adult; Betamethasone; Combined Modality Therapy; Ear Auricle; Female; Follow-Up Studies; | 2019 |
Discussion: Treatment of Keloid Scars with Botulinum Toxin Type A versus Triamcinolone in an Athymic Nude Mouse Model.
Topics: Animals; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Keloid; Mice; Mice, Nude; Triamcinolone | 2019 |
The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Combined Modality Therapy; Dose Fractionation, Radi | 2019 |
Improving the anti-keloid outcomes through liposomes loading paclitaxel-cholesterol complexes.
Topics: Animals; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Cells, Cultured; Cholesterol; Col | 2019 |
The impact of completion thyroidectomy.
Topics: Adenocarcinoma, Follicular; Adolescent; Adult; Aged; Aged, 80 and over; Calcium; Female; Humans; Hyd | 2019 |
STAT3 signalling pathway is implicated in keloid pathogenesis by preliminary transcriptome and open chromatin analyses.
Topics: Animals; Humans; Keloid; Mice; STAT3 Transcription Factor; Transcriptome; Wnt Signaling Pathway | 2019 |
Abnormal scar identification with spherical-nucleic-acid technology.
Topics: Animals; Cells, Cultured; Cicatrix, Hypertrophic; Connective Tissue Growth Factor; Diagnostic Techni | 2018 |
TRAF4 Promotes Fibroblast Proliferation in Keloids by Destabilizing p53 via Interacting with the Deubiquitinase USP10.
Topics: Adolescent; Adult; Cell Proliferation; Cells, Cultured; Child; Cyclin-Dependent Kinase Inhibitor p21 | 2019 |
An Unusual Corneal Mass.
Topics: Aged; Biopsy; Corneal Opacity; Humans; Keloid; Male; Microscopy, Acoustic | 2019 |
The Differential Expression of miRNAs and a Preliminary Study on the Mechanism of miR-194-3p in Keloids.
Topics: Cell Line; Cell Movement; Cell Proliferation; Core Binding Factor Alpha 1 Subunit; Female; Fibroblas | 2019 |
Iatrogenic subglottic tracheal stenosis after tracheostomy and endotracheal intubation: A cohort observational study of more severity in keloid phenotype.
Topics: Adult; Age of Onset; Aged; China; Cohort Studies; Female; Humans; Iatrogenic Disease; Incidence; Int | 2019 |
Normal and keloid fibroblasts are differentially influenced by IFN-γ and triamcinolone as well as by their combination.
Topics: Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblasts; Glucocorticoids; Humans; Interfer | 2019 |
Nitric oxide: Is it the culprit for the continued expansion of keloids?
Topics: Cell Proliferation; Cyclic GMP; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Kel | 2019 |
Retrospective study of immediate postoperative electron radiotherapy for therapy-resistant earlobe keloids.
Topics: Adolescent; Adult; Combined Modality Therapy; Ear Auricle; Female; Humans; Keloid; Male; Middle Aged | 2019 |
Trichostatin A‑induced miR‑30a‑5p regulates apoptosis and proliferation of keloid fibroblasts via targeting BCL2.
Topics: 3' Untranslated Regions; Antagomirs; Apoptosis; Cell Proliferation; Cluster Analysis; Collagen; Epit | 2019 |
Periostin is induced by IL-4/IL-13 in dermal fibroblasts and promotes RhoA/ROCK pathway-mediated TGF-β1 secretion in abnormal scar formation.
Topics: Case-Control Studies; Cell Adhesion Molecules; Cells, Cultured; Cicatrix, Hypertrophic; Dermis; Fibr | 2019 |
Keloidal Morphea: Clinical Picture.
Topics: Diagnosis, Differential; Humans; Keloid; Scleroderma, Localized | 2020 |
Treatment of extensive, recalcitrant keloids using a combination of intralesional cryosurgery, triamcinolone, 5-fluorouracil and hyaluronidase.
Topics: Adrenal Cortex Hormones; Brachytherapy; Cryosurgery; Cryotherapy; Fluorouracil; Humans; Hyaluronoglu | 2019 |
Hypoxia-Induced Epithelial-To-Mesenchymal Transition Mediates Fibroblast Abnormalities via ERK Activation in Cutaneous Wound Healing.
Topics: Cell Hypoxia; Cells, Cultured; Epithelial-Mesenchymal Transition; Fibroblasts; Humans; Hypoxia-Induc | 2019 |
Inhibition of USP4 attenuates pathological scarring by downregulation of the TGF‑β/Smad signaling pathway.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cicatrix; Fibroblasts; Gene Expression | 2019 |
Comparison of intralesional triamcinolone acetonide, botulinum toxin type A, and their combination for the treatment of keloid lesions.
Topics: Adult; Botulinum Toxins, Type A; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Inj | 2020 |
Evaluation of the Role of High-mobility Group Box 1 Protein in Patients With Keloids: A Case Control Study.
Topics: Adult; Biomarkers; Biopsy, Needle; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; | 2019 |
MiR-21 Regulates Keloid Formation by Downregulating Smad7 via the TGF-β/Smad Signaling Pathway.
Topics: Adult; Apoptosis; Cell Proliferation; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Col | 2019 |
Surgical correction of pterygium colli on black skin: Benefit-risk in plastic surgery.
Topics: Black People; Child; Female; Humans; Keloid; Neck; Plastic Surgery Procedures; Postoperative Complic | 2020 |
Nonsurgical Treatment of Keloids and Hypertrophic Scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Prospective Studies | 2019 |
[Keloid treatment : Where do we stand ?]
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Pruritus; Recurrence | 2019 |
Cryosurgery to remove perichondrium for the rabbit ear hypertrophic scar model: a simplified method.
Topics: Animals; Cicatrix, Hypertrophic; Cryosurgery; Disease Models, Animal; Keloid; Rabbits; Wound Healing | 2019 |
High-resolution ultrasound for keloids and hypertrophic scar assessment.
Topics: Adolescent; Cicatrix, Hypertrophic; Erythema; Female; Humans; Keloid; Lasers, Solid-State; Male; Reg | 2020 |
Adjuvant Radiotherapy After Keloid Excision: Preliminary Experience in Taiwan.
Topics: Combined Modality Therapy; Humans; Keloid; Radiotherapy Dosage; Radiotherapy, Adjuvant; Taiwan | 2019 |
The Interplay of Mechanical Stress, Strain, and Stiffness at the Keloid Periphery Correlates with Increased Caveolin-1/ROCK Signaling and Scar Progression.
Topics: Adult; Aged; Case-Control Studies; Caveolin 1; Female; Finite Element Analysis; Humans; Keloid; Male | 2019 |
Discussion: The Interplay of Mechanical Stress, Strain, and Stiffness at the Keloid Periphery Correlates with Increased Caveolin-1/ROCK Signaling and Scar Progression.
Topics: Caveolin 1; Cicatrix, Hypertrophic; Humans; Keloid; Skin; Stress, Mechanical | 2019 |
Knockdown of FOXM1 inhibits activation of keloid fibroblasts and extracellular matrix production via inhibition of TGF-β1/Smad pathway.
Topics: Actins; Adolescent; Adult; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Collagen Ty | 2019 |
Interleukin-6 serum level and gene polymorphism in keloid patients.
Topics: Adolescent; Adult; Case-Control Studies; Egypt; Female; Gene Frequency; Genetic Predisposition to Di | 2019 |
Role of Hypoxia Inducible Factor-1 Alpha (HIF-1α) in Cytoglobin Expression and Fibroblast Proliferation of Keloids.
Topics: Cell Proliferation; Cells, Cultured; Cytoglobin; Fibroblasts; Gene Expression Regulation; Humans; Hy | 2019 |
Metformin Inhibits Epithelial-to-Mesenchymal Transition of Keloid Fibroblasts via the HIF-1α/PKM2 Signaling Pathway.
Topics: Adult; Carrier Proteins; Cell Hypoxia; Cells, Cultured; Down-Regulation; Drug Evaluation, Preclinica | 2019 |
Expression of Components of the Renin-Angiotensin System by the Embryonic Stem Cell-Like Population within Keloid Lesions.
Topics: Adolescent; Adult; Antigens, CD34; Cell Line; Child; Child, Preschool; Embryonic Stem Cells; Female; | 2019 |
Multimodal investigation of a keloid scar by combining mechanical tests in vivo with diverse imaging techniques.
Topics: Arm; Dermis; Epidermis; Female; Humans; Image Processing, Computer-Assisted; Keloid; Microscopy, Con | 2019 |
Pediatric earlobe keloids: Outcomes and patterns of recurrence.
Topics: Adolescent; Ear, External; Female; Humans; Keloid; Male; Recurrence; Treatment Outcome | 2020 |
Association between sphingosine-1-phosphate-induced signal transduction via mitogen-activated protein kinase pathways and keloid formation.
Topics: Adult; Anilides; Anthracenes; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Female; Fi | 2019 |
[Intralesional Cryosurgery in the Treatment of Keloids - A Differentiation of Keloid Types for the Improvement of Patient Selection].
Topics: Cryosurgery; Humans; Injections, Intralesional; Keloid; Patient Selection; Recurrence | 2019 |
Chondroitinase injection improves keloid pathology by reorganizing the extracellular matrix with regenerated elastic fibers.
Topics: Adolescent; Adult; Aged; Animals; Chondroitin ABC Lyase; Drug Evaluation, Preclinical; Elastic Tissu | 2013 |
Combination treatment of CO2 fractional laser, pulsed dye laser, and triamcinolone acetonide injection for refractory keloid scars on the upper back.
Topics: Adult; Anti-Inflammatory Agents; Back; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Hu | 2013 |
Management of keloids in the United States, 1990-2009: an analysis of the National Ambulatory Medical Care Survey.
Topics: Adult; Comorbidity; Female; Glucocorticoids; Health Care Surveys; Humans; Keloid; Male; Practice Pat | 2013 |
Retrospective analysis of earlobe keloids treated with the carbon dioxide laser ablation or cold steel debulking surgery.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Ear, External; Female; Humans; Injections, Intralesiona | 2013 |
Identification and characterization of Wnt signaling pathway in keloid pathogenesis.
Topics: beta Catenin; Cell Differentiation; Cell Proliferation; Fibroblasts; Frizzled Receptors; Glycogen Sy | 2013 |
Identification of steroid sensitive responders versus non-responders in the treatment of keloid disease.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Chi-Square Distribution; Child; Drug Resistance; F | 2013 |
Thalidomide inhibits fibronectin production in TGF-β1-treated normal and keloid fibroblasts via inhibition of the p38/Smad3 pathway.
Topics: Adult; Animals; Base Sequence; Electrophoretic Mobility Shift Assay; Female; Fibroblasts; Fibronecti | 2013 |
Downregulation of type I collagen expression in silibinin-treated human skin fibroblasts by blocking the activation of Smad2/3-dependent signaling pathways: potential therapeutic use in the chemoprevention of keloids.
Topics: Cell Death; Cell Nucleus; Cell Proliferation; Chemoprevention; Collagen Type I; Down-Regulation; Fib | 2013 |
Keloid formation on the great toe after chronic paronychia secondary to ingrown nail.
Topics: Chronic Disease; Female; Humans; Keloid; Nails, Ingrown; Paronychia; Secondary Prevention; Wound Hea | 2013 |
Reverse activated hyrax pressure appliance for treatment of a keloid located at auricula helix.
Topics: Acrylic Resins; Ear Auricle; Ear Diseases; Equipment Design; Humans; Keloid; Pressure; Silicone Elas | 2013 |
[Pseudo-keloid lesion revealing a cutaneous and pulmonary sarcoidosis].
Topics: Humans; Keloid; Male; Middle Aged; Sarcoidosis; Sarcoidosis, Pulmonary; Skin Diseases | 2013 |
Combined treatment of penile keloid: a troublesome complication after circumcision.
Topics: Adult; Bandages; Child; Circumcision, Male; Combined Modality Therapy; Humans; Keloid; Male; Penile | 2013 |
Altered expression of hyaluronan synthase and hyaluronidase mRNA may affect hyaluronic acid distribution in keloid disease compared with normal skin.
Topics: Adolescent; Adult; Cell Adhesion Molecules; Female; Glucuronosyltransferase; GPI-Linked Proteins; Hu | 2013 |
Arthropathy, osteolysis, keloids, relapsing conjunctival pannus and gingival overgrowth: a variant of polyfibromatosis?
Topics: Abnormalities, Multiple; Arthrography; Cleft Palate; Comparative Genomic Hybridization; Conjunctival | 2013 |
A modified technique for removing earlobe keloids.
Topics: Cosmetic Techniques; Ear Diseases; Ear, External; Humans; Keloid | 2013 |
Treatment outcomes for keloid scar management in the pediatric burn population.
Topics: Burns; Female; Humans; Keloid; Male; Steroids | 2013 |
Transformation of keloids is determined by stress occurrence patterns on peri-keloid regions in response to body movement.
Topics: Humans; Keloid; Models, Theoretical; Movement; Stress, Mechanical | 2013 |
[An individualized approach combining local flaps with radiotherapy for the treatment of auricle keloid].
Topics: Adult; Ear, External; Female; Follow-Up Studies; Humans; Keloid; Male; Radiotherapy, Adjuvant; Recur | 2013 |
Tacrolimus fails to regulate collagen expression in dermal fibroblasts.
Topics: Cells, Cultured; Cicatrix, Hypertrophic; Collagen; Fibroblasts; Gene Expression; Genome-Wide Associa | 2013 |
A short educational intervention measurably benefits keloid-prone individuals' knowledge of prevention and treatment.
Topics: Adult; Aged; Body Piercing; Female; Follow-Up Studies; Health Knowledge, Attitudes, Practice; Humans | 2013 |
Keloids: an update on medical and surgical treatments.
Topics: Foreign-Body Reaction; Humans; Keloid; Patient Education as Topic; Recurrence; Skin; Wound Closure T | 2013 |
Are auricular keloids and persistent hypertrophic scars resectable? The role of intrascar excision.
Topics: Cicatrix, Hypertrophic; Ear, External; Female; Humans; Keloid; Male; Plastic Surgery Procedures | 2014 |
Association study confirmed susceptibility loci with keloid in the Chinese Han population.
Topics: Adult; Asian People; Ethnicity; Female; Genetic Loci; Genetic Predisposition to Disease; Haplotypes; | 2013 |
Comparative study of microRNA profiling in keloid fibroblast and annotation of differential expressed microRNAs.
Topics: Cells, Cultured; Cluster Analysis; Fibroblasts; Gene Expression Profiling; Humans; Keloid; MicroRNAs | 2013 |
Effects of botulinum toxin type A on expression of genes in keloid fibroblasts.
Topics: Botulinum Toxins, Type A; Cell Proliferation; Cells, Cultured; Dermatologic Agents; Fibroblasts; Gen | 2014 |
Acro-osteolysis, keloid like-lesions, distinctive facial features, and overgrowth: two newly recognized patients with premature aging syndrome, Penttinen type.
Topics: Acro-Osteolysis; Adolescent; Child; Collagen Type III; Face; Humans; Keloid; Lamin Type A; Limb Defo | 2013 |
[Expression and significance of DNMT1 in human keloid fibroblast].
Topics: Adolescent; Adult; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methylt | 2013 |
Is survivin a novel pathway for the treatment and pathogenesis of keloid?
Topics: Apoptosis; Cell Proliferation; Gene Expression Regulation; Humans; Inhibitor of Apoptosis Proteins; | 2013 |
Benefits of conservative "wait and see" approach for recurrent plantar keloid.
Topics: Adult; Foot Diseases; Foot Orthoses; Humans; Keloid; Male; Middle Aged; Recurrence; Shoes; Walking; | 2013 |
A study of the combination of triamcinolone and 5-fluorouracil in modulating keloid fibroblasts in vitro.
Topics: Analysis of Variance; Apoptosis; Blotting, Western; Cell Cycle; Cell Death; Cell Proliferation; Cell | 2013 |
Ex vivo evaluation of antifibrotic compounds in skin scarring: EGCG and silencing of PAI-1 independently inhibit growth and induce keloid shrinkage.
Topics: Adolescent; Adult; Apoptosis; Catechin; Cell Proliferation; Collagen; Dexamethasone; Gene Knockdown | 2013 |
Systemic sclerosis with multiple nodules: characterization of the extracellular matrix.
Topics: Cartilage Oligomeric Matrix Protein; Cells, Cultured; Collagen Type XII; Extracellular Matrix; Femal | 2013 |
Tuberculosis verrucosa cutis in a patient with keloid over ear lobule.
Topics: Adult; Ear Auricle; Female; Humans; Keloid; Tuberculosis, Cutaneous | 2013 |
The TaqI gene polymorphisms of VDR and the circulating 1,25-dihydroxyvitamin D levels confer the risk for the keloid scarring in Chinese cohorts.
Topics: Adult; Alleles; Area Under Curve; Asian People; China; Cohort Studies; Female; Gene Frequency; Genet | 2013 |
Keloid-like morphoea.
Topics: Child; Female; Humans; Hyperpigmentation; Keloid; Scleroderma, Localized | 2014 |
Earlobe keloids: a pilot study of the efficacy of keloidectomy with core fillet flap and adjuvant intralesional corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Chemotherapy, Adjuvant; Cosmetic Techniques; Dermatologi | 2013 |
Keloidal basal cell carcinoma: should it be considered a distinct entity?
Topics: Carcinoma, Basal Cell; Diagnosis, Differential; Humans; Keloid; Male; Middle Aged; Skin Neoplasms; T | 2013 |
A method of scar evaluation using non-contact 3D scanner.
Topics: Acne Vulgaris; Adult; Aged; Female; Humans; Imaging, Three-Dimensional; Keloid; Male; Middle Aged | 2013 |
Comparative effect of topical silicone gel and topical tretinoin cream for the prevention of hypertrophic scar and keloid formation and the improvement of scars.
Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix, Hypertrophic; F | 2014 |
Radiofrequency ablation for treatment of auricular keloids: our experience in eleven patients.
Topics: Adolescent; Adult; Aged; Body Piercing; Catheter Ablation; Child; Cohort Studies; Ear Auricle; Femal | 2013 |
[Expressions of the related genes in fibroblasts of human keloid and the effect of artesunate].
Topics: Adolescent; Adult; Apoptosis; Artemisinins; Artesunate; Cell Proliferation; Cells, Cultured; Female; | 2013 |
[Bilateral keloids secondary to otoplasty treated by excision and keloids flaps].
Topics: Child; Ear, External; Female; Humans; Keloid; Plastic Surgery Procedures; Surgical Flaps | 2013 |
Keloids and non-diabetic kidney disease: similarities and the APOL1-MYH9 haplotype as a possible genetic link.
Topics: Apolipoprotein L1; Apolipoproteins; Black People; Haplotypes; Humans; Keloid; Kidney Diseases; Linka | 2013 |
Equine exuberant granulation tissue and human keloids: a comparative histopathologic study.
Topics: Animals; Cicatrix, Hypertrophic; Dermis; Epidermis; Fibrosis; Gene Expression Regulation; Horse Dise | 2013 |
siRNA knockdown of tissue inhibitor of metalloproteinase-1 in keloid fibroblasts leads to degradation of collagen type I.
Topics: Apoptosis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Collagenases; Culture | 2014 |
Immunohistochemical evaluation of COX-1 and COX-2 expression in keloid and hypertrophic scar.
Topics: Adolescent; Adult; Biopsy; Case-Control Studies; Child; Cicatrix, Hypertrophic; Cyclooxygenase 1; Cy | 2014 |
Effect of enoxaparin and onion extract on human skin fibroblast cell line - therapeutic implications for the treatment of keloids.
Topics: Apoptosis; Cell Line; Cell Proliferation; Cicatrix, Hypertrophic; Dose-Response Relationship, Drug; | 2014 |
Outcomes of surgical excision with pressure therapy using magnets and identification of risk factors for recurrent keloids.
Topics: Bandages; Ear Diseases; Ear, External; Female; Humans; Keloid; Magnetic Field Therapy; Male; Pressur | 2013 |
Reply: Outcomes of surgical excision with pressure therapy using magnets and identification of risk factors for recurrent keloids.
Topics: Bandages; Ear Diseases; Ear, External; Female; Humans; Keloid; Magnetic Field Therapy; Male; Pressur | 2013 |
Another treatment option for keloids.
Topics: Humans; Keloid | 2013 |
Corneal keloid: report of natural history and outcome of surgical management in two cases.
Topics: Artificial Organs; Cornea; Corneal Diseases; Corneal Surgery, Laser; Humans; Keloid; Keratoplasty, P | 2013 |
Clival keloid after nasopharyngeal radium irradiation masquerading as skull base malignancy.
Topics: Aged; Bone Diseases; Chronic Disease; Cranial Fossa, Posterior; Diagnosis, Differential; Humans; Kel | 2014 |
Treatment of earlobe keloids by surgical excision and cryosurgery.
Topics: Adolescent; Adult; Child; Cryosurgery; Dermatologic Surgical Procedures; Ear, External; Female; Foll | 2014 |
Effects of botulinum toxin A on patient-specific keloid fibroblasts in vitro.
Topics: Adolescent; Adult; Botulinum Toxins, Type A; Cell Proliferation; Cells, Cultured; Cytokines; Enzyme- | 2014 |
A novel hydrogel scaffold for the prevention or reduction of the recurrence of keloid scars postsurgical excision.
Topics: Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Keloid; Prospective Studies; Recurrence; Tissu | 2013 |
Wound-healing and potential anti-keloidal properties of the latex of Calotropis procera (Aiton) Asclepiadaceae in rabbits.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Calotropis; Collagen; Glycosides; Honey; Keloid; Latex | 2013 |
Analysis of surgical treatments for earlobe keloids: analysis of 174 lesions in 145 patients.
Topics: Ear Diseases; Ear, External; Humans; Keloid | 2013 |
Temporoparietal scalp keloid: an unusual occurrence.
Topics: Biopsy, Needle; Combined Modality Therapy; Craniocerebral Trauma; Follow-Up Studies; Humans; Immunoh | 2015 |
The natural history and spontaneous resolution of keloid scars.
Topics: Adult; Aged; Female; Humans; Keloid; Male; Middle Aged; Prognosis; Remission Induction; Remission, S | 2014 |
The use of the 300 microsecond 1064 nm Nd:YAG laser in the treatment of keloids.
Topics: Adult; Analysis of Variance; Chemotherapy, Adjuvant; Erythema; Glucocorticoids; Humans; Injections, | 2013 |
[Identification of differently expressed microRNAs in keloid and pilot study on biological function of miR-199a-5p].
Topics: Cell Proliferation; Cells, Cultured; Down-Regulation; Female; Fibroblasts; Gene Expression Profiling | 2013 |
[Effect of the methylation enzyme inhibitors of 5-aza-2-deoxycytidine on the TGF-beta/smad signal transduction pathway in human keloid fibroblasts].
Topics: Apoptosis; Azacitidine; Cell Proliferation; Cells, Cultured; Decitabine; Enzyme Inhibitors; Female; | 2013 |
A keloid edge precut, preradiotherapy method in large keloid skin graft treatment.
Topics: Adolescent; Adult; Female; Humans; Keloid; Male; Patient Satisfaction; Radiotherapy, Adjuvant; Skin | 2014 |
Keloid of the toe: Novel pressure treatment.
Topics: Adult; Compression Bandages; Female; Foot Dermatoses; Humans; Keloid; Physical Stimulation; Pressure | 2014 |
Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation.
Topics: Base Sequence; Cell Proliferation; Centella; Collagen; DNA Primers; Fibroblasts; Gene Silencing; Hum | 2013 |
Keloid on scapular area secondary to therapeutic dry cupping.
Topics: Complementary Therapies; Humans; Keloid; Shoulder; Suction | 2015 |
Variety of complications after auricle piercing.
Topics: Adolescent; Adult; Body Piercing; Child; Cicatrix, Hypertrophic; Ear Auricle; Ear Deformities, Acqui | 2014 |
Human keloid cell characterization and inhibition of growth with human Wharton's jelly stem cell extracts.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Cycle; Cell Differentiation; Cel | 2014 |
Increased c-Met phosphorylation is related to keloid pathogenesis: implications for the biological behaviour of keloid fibroblasts.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cell Proliferation; Cells, Cultured; Collagen; Female; F | 2014 |
Hematopoietic stem cells: do they have a role in keloid pathogenesis?
Topics: Adult; Antigens, CD34; Biomarkers; Case-Control Studies; Female; Hematopoietic Stem Cells; Humans; I | 2014 |
Impact of MiR-21 on the expression of FasL in the presence of TGF-β1.
Topics: Apoptosis; Case-Control Studies; Cell Movement; Cell Proliferation; Cells, Cultured; Fas Ligand Prot | 2013 |
Superficial plantar fibromatosis.
Topics: Diagnosis, Differential; Fasciitis, Plantar; Fibroma; Foot Diseases; Histiocytoma, Benign Fibrous; H | 2013 |
Site-specific keloid fibroblasts alter the behaviour of normal skin and normal scar fibroblasts through paracrine signalling.
Topics: Adult; Aged; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Cicatrix; Cultur | 2013 |
Clinical considerations for allied professionals: optimizing outcomes: surgical incision techniques and wound care in device implantation.
Topics: Allied Health Personnel; Cicatrix; Esthetics; Hematoma; Humans; Keloid; Postoperative Care; Postoper | 2014 |
Co-delivery of dexamethasone and green tea polyphenols using electrospun ultrafine fibers for effective treatment of keloid.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bandages; Cells, | 2014 |
Annexin A2 participates in human skin keloid formation by inhibiting fibroblast proliferation.
Topics: Adolescent; Adult; Aged; Annexin A2; Apoferritins; Carboxylic Ester Hydrolases; Cell Proliferation; | 2014 |
[Inhibitory effect of Typhonium gigantewm Engl. on in vitro cultured human keloid fibroblasts].
Topics: Apoptosis; Cell Proliferation; Cells, Cultured; Drugs, Chinese Herbal; Fibroblasts; Humans; Keloid | 2013 |
Insufficient expression of the melanocortin-1 receptor by human dermal fibroblasts contributes to excess collagen synthesis in keloid scars.
Topics: alpha-MSH; Collagen; Fibroblasts; Gene Expression Regulation; Humans; Keloid; Melanocytes; Receptor, | 2013 |
Effect of human Wharton's jelly mesenchymal stem cell paracrine signaling on keloid fibroblasts.
Topics: Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Diffusion Chambers, Culture; F | 2014 |
Multimodal keloid therapy with excision, application of mitomycin C, and radiotherapy.
Topics: Adult; Antibiotics, Antineoplastic; Chemoradiotherapy, Adjuvant; Dose Fractionation, Radiation; Fema | 2014 |
[Local complications of lip and tongue piercing -- report of the cases].
Topics: Adolescent; Adult; Body Piercing; Face; Female; Foreign-Body Reaction; Humans; Keloid; Lip; Mouth; T | 2013 |
Associations between keloid severity and single-nucleotide polymorphisms: importance of rs8032158 as a biomarker of keloid severity.
Topics: Endosomal Sorting Complexes Required for Transport; Genetic Markers; HapMap Project; Humans; Japan; | 2014 |
Nape keloid folicullitis and pruritus.
Topics: Folliculitis; Humans; Keloid; Models, Theoretical; Pruritus; Staphylococcus aureus | 2014 |
[Effect of two dose fractionations on postoperative radiotherapy of keloid: an analysis of 107 patients].
Topics: Dose Fractionation, Radiation; Humans; Keloid; Postoperative Period; Recurrence | 2014 |
[Scars and keloids].
Topics: Cicatrix; Humans; Keloid; Wounds and Injuries | 1950 |
Collagenase followed by compression for the treatment of earlobe keloids.
Topics: Adult; Collagenases; Dermatologic Agents; Ear, External; Female; Humans; Injections, Intralesional; | 2014 |
Treg-enriched CD4+ T cells attenuate collagen synthesis in keloid fibroblasts.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Child; Coculture Techniques; Colla | 2014 |
[The clinical classification method research of keloid].
Topics: Humans; Keloid | 2013 |
Hypertrophic and keloid scars after the application of 5% imiquimod cream: a report of 2 cases.
Topics: Adult; Aged; Aminoquinolines; Cicatrix, Hypertrophic; Dosage Forms; Drug Eruptions; Female; Humans; | 2014 |
Clinical implications of single- versus multiple-site keloid disorder: a retrospective study in an Asian population.
Topics: Adolescent; Adult; Asian People; Cross-Sectional Studies; Female; Genetic Predisposition to Disease; | 2015 |
[Differential diagnosis between keloid and hypertrophic scars: a new approach by full-field optical coherence tomography].
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Diagnosis, Differential; Female; Humans; Kel | 2014 |
Effect of collagen nanotopography on keloid fibroblast proliferation and matrix synthesis: implications for dermal wound healing.
Topics: Cell Proliferation; Collagen; Dermis; Extracellular Matrix; Female; Fibroblasts; Humans; Keloid; Mal | 2014 |
Keloid of the circumcision scar: a rare complication.
Topics: Child; Circumcision, Male; Humans; Keloid; Male | 2015 |
The application of the starfish hatching enzyme for the improvement of scar and keloid based on the fibroblast-populated collagen lattice.
Topics: Animals; Collagen; Fibroblasts; Humans; Interleukin-1beta; Keloid; Matrix Metalloproteinase 2; Matri | 2014 |
[Treatment of auricular keloids with surgery and intralesional injection of compound betamethasone].
Topics: Adolescent; Adult; Betamethasone; Combined Modality Therapy; Ear Auricle; Female; Humans; Injections | 2014 |
Mast cells prevent dexamethasone-induced cell death of cultured fibroblasts: relationship to gap junctional intercellular communications.
Topics: Animals; Apoptosis; Cell Communication; Cell Line; Cicatrix, Hypertrophic; Coculture Techniques; Cyt | 2014 |
Analysis of surgical treatments for earlobe keloids: analysis of 174 lesions in 145 patients.
Topics: Ear Diseases; Ear, External; Humans; Keloid | 2014 |
Reply: Analysis of surgical treatments for earlobe keloids: analysis of 174 lesions in 145 patients.
Topics: Ear Diseases; Ear, External; Humans; Keloid | 2014 |
Keloid microRNA expression analysis and the influence of miR-199a-5p on the proliferation of keloid fibroblasts.
Topics: Cell Proliferation; Fibroblasts; Gene Expression Regulation; Humans; Keloid; Microarray Analysis; Mi | 2014 |
[Keloid scars of the external ear: a non solved problem].
Topics: Adolescent; Child; Child, Preschool; Ear, External; Female; Glucocorticoids; Humans; Infant; Keloid; | 2014 |
Increased periostin expression affects the proliferation, collagen synthesis, migration and invasion of keloid fibroblasts under hypoxic conditions.
Topics: Adult; Apoptosis; Cell Adhesion Molecules; Cell Cycle; Cell Hypoxia; Cell Movement; Cell Proliferati | 2014 |
Transcriptional profiling of rapamycin-treated fibroblasts from hypertrophic and keloid scars.
Topics: Adult; Aged; Cicatrix, Hypertrophic; Collagen; Dose-Response Relationship, Drug; Down-Regulation; Fe | 2014 |
Effect of captopril on collagen metabolisms in keloid fibroblast cells.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blotting, Western; Captopril; Cells, Cultured; Collagen; F | 2016 |
An important case of misdiagnosis: keloid scar or high-grade soft-tissue sarcoma?
Topics: Biopsy; Diagnosis, Differential; Diagnostic Errors; Female; Humans; Keloid; Middle Aged; Sarcoma; Th | 2014 |
[Preliminary study on CASK/Id1 pathway in fibroblasts of human keloid].
Topics: Cell Proliferation; Cyclin-Dependent Kinase Inhibitor Proteins; Fibroblasts; Humans; Inhibitor of Di | 2014 |
Cochlear implant extrusion secondary to keloid formation.
Topics: Adult; Cochlear Implantation; Cochlear Implants; Device Removal; Hearing Loss; Humans; Keloid; Male; | 2014 |
RUNX3 expression is associated with sensitivity to pheophorbide a-based photodynamic therapy in keloids.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apoptosis; Cell Proliferation; Cell Survival; Child; Chl | 2015 |
NADPH oxidase-2 is a key regulator of human dermal fibroblasts: a potential therapeutic strategy for the treatment of skin fibrosis.
Topics: Cells, Cultured; Collagen; Enzyme Inhibitors; Fibroblasts; Fibrosis; Gene Knockdown Techniques; Huma | 2014 |
Reduced FOXO1 expression accelerates skin wound healing and attenuates scarring.
Topics: Animals; Blotting, Western; Cicatrix; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; For | 2014 |
Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin.
Topics: Adult; Ascorbic Acid; Biopsy; Collagen; Elasticity; Elastin; Extracellular Matrix; Female; Fibroblas | 2014 |
The structure of the basement membrane zone differs between keloids, hypertrophic scars and normal skin: a possible background to an impaired function.
Topics: Adolescent; Adult; Basement Membrane; Biopsy; Child; Cicatrix, Hypertrophic; Collagen; Female; Human | 2014 |
Where we stand with human hypertrophic and keloid scar models.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid; Tissue Engineering | 2014 |
Embedded earring back mistaken for ear lobe keloid in an eight-year-old girl.
Topics: Child; Device Removal; Diagnosis, Differential; Ear Auricle; Ear Diseases; False Positive Reactions; | 2014 |
Intralesional cryosurgery combined with topical silicone gel sheeting for the treatment of refractory keloids.
Topics: Administration, Cutaneous; Adult; Combined Modality Therapy; Cryosurgery; Erythema; Female; Humans; | 2014 |
Requirement of Gαi1/3-Gab1 signaling complex for keratinocyte growth factor-induced PI3K-AKT-mTORC1 activation.
Topics: Adaptor Proteins, Signal Transducing; Cell Movement; Fibroblast Growth Factor 7; Gene Knockdown Tech | 2015 |
Keloid incidence in Asian people and its comorbidity with other fibrosis-related diseases: a nationwide population-based study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asian People; Child; Child, Preschool; China; Comorbidit | 2014 |
Plantar keloids: diagnostic and therapeutic issues in six patients.
Topics: Adjuvants, Immunologic; Adult; Aminoquinolines; Biopsy; Colchicine; Dermatologic Surgical Procedures | 2015 |
[The expressions of notch genes in human keloid-derived mesenchymal-like stem cells].
Topics: Adolescent; Cells, Cultured; Child; Female; Humans; Keloid; Male; Mesenchymal Stem Cells; Receptors, | 2014 |
Hypertrophic scars and keloids in surgery: current concepts.
Topics: Cicatrix, Hypertrophic; Dermatologic Surgical Procedures; Epidermis; Humans; Keloid; Skin Physiologi | 2014 |
Mast cell chymase in keloid induces profibrotic response via transforming growth factor-β1/Smad activation in keloid fibroblasts.
Topics: Adult; Blotting, Western; Chymases; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fibrosis | 2014 |
Ocular pterygium--digital keloid dysplasia.
Topics: Child; Child, Preschool; Facies; Fingers; Humans; Keloid; Male; Phenotype; Pterygium; Skin Pigmentat | 2014 |
Transdermal delivery of 10,11-methylenedioxycamptothecin by hyaluronic acid based nanoemulsion for inhibition of keloid fibroblast.
Topics: Animals; Camptothecin; Cell Cycle; Emulsions; Fibroblasts; Gene Expression Regulation; Humans; Hyalu | 2014 |
Excision, skin grafting, corticosteroids, adjuvant radiotherapy, pressure therapy, and emancipation: the ESCAPE model for successful taming of giant auricular keloids.
Topics: Adolescent; Adult; Ambulatory Care; Body Piercing; Combined Modality Therapy; Ear Auricle; Ear Defor | 2014 |
Expression of insulin-like growth factor-1 receptor in keloid and hypertrophic scar.
Topics: Adolescent; Adult; Analysis of Variance; Blotting, Western; Case-Control Studies; Cicatrix, Hypertro | 2014 |
Imaging of collagen deposition disorders using optical coherence tomography.
Topics: Adult; Cicatrix, Hypertrophic; Collagen; Humans; Keloid; Lichen Sclerosus et Atrophicus; Middle Aged | 2015 |
Topical verapamil as a scar modulator.
Topics: Abdominoplasty; Administration, Topical; Adult; Aged; Calcium Channel Blockers; Cicatrix, Hypertroph | 2014 |
Association of ADAM33 gene polymorphisms with keloid scars in a northeastern Chinese population.
Topics: ADAM Proteins; Alleles; Base Sequence; Case-Control Studies; China; DNA Primers; Genotype; Haplotype | 2014 |
Rare genetic diseases, signalling pathways, and keloid scar formation.
Topics: Female; Humans; Keloid; Male; Rubinstein-Taybi Syndrome | 2014 |
Intralesional cryosurgery to treat keloid scars: results from a retrospective study.
Topics: Adolescent; Adult; Aged; Cicatrix; Cryosurgery; Esthetics; Female; Follow-Up Studies; Humans; Keloid | 2014 |
[Surgical treatment of auricular keloid by developing a flap of scar tissue].
Topics: Adolescent; Adult; Ear Auricle; Female; Humans; Keloid; Surgical Flaps; Young Adult | 2014 |
Admixture mapping identifies a locus at 15q21.2-22.3 associated with keloid formation in African Americans.
Topics: Black or African American; Case-Control Studies; Chromosome Mapping; Chromosomes, Human, Pair 15; Ex | 2014 |
The ultraviolet A-activated photosensitizer 2-(4-aminophenyl)-7-methoxybenzothiazole suppresses proliferation and induces apoptosis of keloid fibroblasts: a potential adjunctive therapy for keloids.
Topics: Aniline Compounds; Apoptosis; Benzothiazoles; Cell Proliferation; Cells, Cultured; Fibroblasts; Huma | 2015 |
Osteopontin expression in healing wounds of horses and in human keloids.
Topics: Animals; Gene Expression Regulation; Horses; Humans; Keloid; Osteopontin; Polymerase Chain Reaction; | 2016 |
Differential susceptible loci expression in keloid and hypertrophic scars in the Chinese Han population.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asian People; Carrier Proteins; Cell Cycle Proteins; Chi | 2015 |
[Ointments, cortisone injections, lasers. What will smooth hypertrophic scars?].
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Guideline Adherence; Keloid; Plastic Surgery Proc | 2014 |
[Long-term results of postoperative electronic irradiation for 53 patients with keloids].
Topics: Adolescent; Adult; Aged; Female; Follow-Up Studies; Humans; Keloid; Male; Middle Aged; Postoperative | 2014 |
[The preliminary study of structure variation related to keloid based on the whole-gene resequencing technique].
Topics: Base Sequence; Female; Humans; Keloid; Male; Molecular Sequence Data; Pedigree; Sequence Analysis; T | 2014 |
[The effects of conditioned medium from keloid fibroblasts under hypoxia on angiogenesis].
Topics: Cell Hypoxia; Cells, Cultured; Culture Media, Conditioned; Fibroblasts; Humans; Keloid; Neovasculari | 2014 |
The effects of Wubeizi ointment on the proliferation of keloid-derived fibroblasts.
Topics: Cell Cycle; Cell Proliferation; Drugs, Chinese Herbal; Fibroblasts; Humans; Keloid; Ointments; Rhus | 2015 |
Association of the plasminogen activator inhibitor-1 (PAI-1) Gene -675 4G/5G and -844 A/G promoter polymorphism with risk of keloid in a Chinese Han population.
Topics: Adolescent; Adult; Base Sequence; Child; China; DNA Primers; Ethnicity; Female; Humans; Keloid; Male | 2014 |
Adipose tissue-derived stromal cells inhibit TGF-β1-induced differentiation of human dermal fibroblasts and keloid scar-derived fibroblasts in a paracrine fashion.
Topics: Adipose Tissue; Cell Differentiation; Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid; Paracrine | 2014 |
MicroRNA-21 affects proliferation and apoptosis by regulating expression of PTEN in human keloid fibroblasts.
Topics: Apoptosis; Cell Proliferation; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Humans; Kel | 2014 |
Forty-five cases of chest keloids treated with subcutaneous super-tension-reduction suture combined with postoperative electron-beam irradiation.
Topics: Adolescent; Adult; Combined Modality Therapy; Female; Humans; Keloid; Male; Middle Aged; Radiotherap | 2014 |
Upregulated periostin promotes angiogenesis in keloids through activation of the ERK 1/2 and focal adhesion kinase pathways, as well as the upregulated expression of VEGF and angiopoietin‑1.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiopoietin-1; Cell Adhesion Molecules; Cell Movement; | 2015 |
Phosphorylation of the ribosomal protein S6, a marker of mTOR (mammalian target of rapamycin) pathway activation, is strongly increased in hypertrophic scars and keloids.
Topics: Actins; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cicatrix, Hypertrophic; Female; Fluo | 2015 |
An unusual skin lesion due to confluent postmortem ecchymoses in keloid scars.
Topics: Borderline Personality Disorder; Ecchymosis; Erythrocytes; Humans; Keloid; Male; Postmortem Changes; | 2015 |
Ionizing irradiation inhibits keloid fibroblast cell proliferation and induces premature cellular senescence.
Topics: Adolescent; Adult; Cell Cycle; Cell Proliferation; Cells, Cultured; Cellular Senescence; Child; Fema | 2015 |
Intralesional vs. contact cryosurgery in treatment of keloids: a clinical and immunohistochemical study.
Topics: Adolescent; Adult; Cryosurgery; Female; Humans; Immunohistochemistry; Keloid; Male; Middle Aged; Ten | 2015 |
Binder clips in the treatment of auricular keloids.
Topics: Ear, External; Household Articles; Humans; Keloid; Male; Postoperative Period; Pressure | 2014 |
Antifibrogenic effects of B16 melanoma-conditioned medium.
Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Culture Media, C | 2015 |
Light-emitting diode-generated red light inhibits keloid fibroblast proliferation.
Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Color; Fibroblasts; Humans; Keloid; Radiation Do | 2015 |
Light-emitting diode-generated red light inhibits keloid fibroblast proliferation.
Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Color; Fibroblasts; Humans; Keloid; Radiation Do | 2015 |
Light-emitting diode-generated red light inhibits keloid fibroblast proliferation.
Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Color; Fibroblasts; Humans; Keloid; Radiation Do | 2015 |
Light-emitting diode-generated red light inhibits keloid fibroblast proliferation.
Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Color; Fibroblasts; Humans; Keloid; Radiation Do | 2015 |
The antimicrobial peptides psoriasin (S100A7) and koebnerisin (S100A15) suppress extracellular matrix production and proliferation of human fibroblasts.
Topics: Cell Proliferation; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type | 2015 |
[Effect of lentivirus-mediated hIL-24 gene on proliferation, migration and invasion of keloid fibroblasts].
Topics: Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Fibroblasts; Genet | 2014 |
Complete earlobe keloid resection with fistulectomy.
Topics: Adolescent; Adult; Dermatologic Surgical Procedures; Ear Auricle; Female; Humans; Keloid; Male; Midd | 2015 |
Liposome-Adenoviral hTERT-siRNA Knockdown in Fibroblasts from Keloids Reduce Telomere Length and Fibroblast Growth.
Topics: Apoptosis; Cells, Cultured; Fibroblasts; Humans; Keloid; Telomerase; Telomere Homeostasis | 2015 |
Premature collagen fibril formation, fibroblast-mast cell interactions and mast cell-mediated phagocytosis of collagen in keloids.
Topics: Cell Communication; Collagen; Extracellular Matrix; Fibroblasts; Humans; Keloid; Mast Cells; Phagocy | 2015 |
[Analysis on polymorphism at -509 C/T site of TGF-β1 gene in patients with keloids].
Topics: Alleles; Gene Frequency; Genotype; Humans; Keloid; Polymorphism, Genetic; Transforming Growth Factor | 2014 |
Protein-protein interaction network of gene expression in the hydrocortisone-treated keloid.
Topics: Gene Expression Regulation; Humans; Hydrocortisone; Keloid; Protein Interaction Maps | 2015 |
High-dose-rate brachytherapy for the treatment of recalcitrant keloids: a unique, effective treatment protocol.
Topics: Brachytherapy; Female; Humans; Keloid; Male | 2015 |
Keloid Pathogenesis: Potential Role of Cellular Fibronectin with the EDA Domain.
Topics: Animals; Blotting, Western; Cells, Cultured; Ectodysplasins; Fibroblasts; Fibronectins; Gene Express | 2015 |
[Keloid scars: a case series study].
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; Middle Aged; R | 2015 |
Keloidal basal cell carcinoma possibly developed from classical nodulo-ulcerative type of basal cell carcinoma: report of a case.
Topics: Aged, 80 and over; Carcinoma, Basal Cell; Dermoscopy; Female; Humans; Keloid; Skin Neoplasms | 2015 |
Reply: High-dose-rate brachytherapy for the treatment of recalcitrant keloids: a unique effective treatment protocol.
Topics: Brachytherapy; Female; Humans; Keloid; Male | 2015 |
An abnormality in glucocorticoid receptor expression differentiates steroid responders from nonresponders in keloid disease.
Topics: Adult; Analysis of Variance; Cicatrix; Female; Humans; Immunohistochemistry; Keloid; Male; Middle Ag | 2015 |
Does ear keloid formation depend on the type of earrings or piercing jewellery?
Topics: Adolescent; Adult; Body Piercing; Child; Ear Diseases; Ear, External; Female; Humans; Jewelry; Keloi | 2015 |
Analysis of the surgical treatments of 63 keloids on the cartilaginous part of the auricle: effectiveness of the core excision method.
Topics: Ear Auricle; Ear Cartilage; Female; Follow-Up Studies; Humans; Keloid; Male; Plastic Surgery Procedu | 2015 |
The effect of 595 nm pulsed dye laser on connective tissue growth factor (CTGF) expression in cultured keloid fibroblasts.
Topics: Apoptosis; Cell Culture Techniques; Cell Cycle; Cell Proliferation; Connective Tissue Growth Factor; | 2015 |
Histomorphometric analysis of collagen architecture of auricular keloids in an Asian population.
Topics: Adolescent; Adult; Asian People; Cell Aggregation; Cell Count; Cohort Studies; Collagen; Ear Auricle | 2015 |
[Clinical analysis of treatment of earlap keloid].
Topics: Ear; Humans; Keloid | 2014 |
Cutaneous dirt-adherent disease on the base of keloid.
Topics: Depression; Humans; Keloid; Male; Middle Aged; Skin Diseases | 2015 |
Keloid-derived keratinocytes acquire a fibroblast-like appearance and an enhanced invasive capacity in a hypoxic microenvironment in vitro.
Topics: Biomarkers; Biopsy; Cadherins; Cell Hypoxia; Cell Movement; Cells, Cultured; Cellular Microenvironme | 2015 |
[Diagnosis and evolution of a keloid].
Topics: Disease Progression; Humans; Keloid; Male; Young Adult | 2014 |
Efficacy of IPL device combined with intralesional corticosteroid injection for the treatment of keloids and hypertrophic scars with regards to the recovery of skin barrier function: A pilot study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Child; Cicatrix, Hypertrophic; Combined Modality T | 2015 |
Anatomopathological findings in scars: comparative study between different specimens.
Topics: Actins; Adult; Apoptosis; Burns; Cicatrix; Cicatrix, Hypertrophic; Collagen; Female; Humans; Inflamm | 2015 |
Epidemiology of keloids in normally pigmented Africans and African people with albinism: population-based cross-sectional survey.
Topics: Adult; Albinism; Black People; Cicatrix; Cross-Sectional Studies; Female; Humans; Keloid; Kenya; Mal | 2015 |
Images in clinical medicine. Incisional keloid.
Topics: Back; Glucocorticoids; Humans; Keloid; Male; Postoperative Complications; Young Adult | 2015 |
Decorin-expressing adenovirus decreases collagen synthesis and upregulates MMP expression in keloid fibroblasts and keloid spheroids.
Topics: Adenoviridae; Cells, Cultured; Collagen Type I; Collagen Type III; Decorin; Extracellular Matrix Pro | 2015 |
The dermatology life quality index as a means to assess life quality in patients with different scar types.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atrophy; Cicatrix; Cicatrix, Hypertrophic; Female; Human | 2015 |
2ME2 increase radiation-induced apoptosis of keloid fibroblasts by targeting HIF-1α in vitro.
Topics: 2-Methoxyestradiol; Apoptosis; Cell Proliferation; Estradiol; Fibroblasts; Gene Knockdown Techniques | 2016 |
Mechanical coupling of cytoskeletal elasticity and force generation is crucial for understanding the migrating nature of keloid fibroblasts.
Topics: Actin Cytoskeleton; Animals; Cell Movement; Cell Polarity; Cytoskeleton; Elasticity; Fibroblasts; Fo | 2015 |
Frontometaphyseal dysplasia and keloid formation without FLNA mutations.
Topics: Adolescent; Child; Chromosome Duplication; Chromosomes, Human, Pair 22; Cleft Palate; Female; Filami | 2015 |
Radiotherapy following surgery in keloid treatment: our protocol.
Topics: Adult; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Keloid; Male; Middle Aged; Radi | 2016 |
Chest wall abscesses due to continuous application of silicone gel sheets for keloid management.
Topics: Abscess; Aged; Anti-Bacterial Agents; Humans; Keloid; Male; Occlusive Dressings; Silicone Gels; Swea | 2015 |
Flash-lamp pulsed-dye laser treatment of keloids: results of an observational study.
Topics: Adult; Cicatrix, Hypertrophic; Female; Humans; Keloid; Lasers, Dye; Low-Level Light Therapy; Male; T | 2015 |
Force generation and transmission in keloid fibroblasts: dissecting the role of mechanosensitive molecules in cell function.
Topics: Animals; Cytoskeleton; Fibroblasts; Humans; Keloid | 2015 |
Role of verapamil in preventing and treating hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Databases, Factual; Humans; Keloid; Verapamil | 2016 |
Combination of radiofrequency and intralesional steroids in the treatment of keloids: a pilot study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Combined Modality Therapy; Female; Humans; Hyperthermia | 2015 |
Intralesional Cryotherapy for Treatment of Keloid Scars: A Prospective Study.
Topics: Cryosurgery; Female; Humans; Keloid; Male | 2015 |
Reply: Intralesional Cryotherapy for the Treatment of Keloid Scars: A Prospective Study.
Topics: Cryosurgery; Female; Humans; Keloid; Male | 2015 |
Reply: Intralesional Cryotherapy for the Treatment of Keloid Scars: A Prospective Study.
Topics: Cryosurgery; Female; Humans; Keloid; Male | 2015 |
Intralesional Cryotherapy for the Treatment of Keloid Scars: A Prospective Study.
Topics: Cryosurgery; Female; Humans; Keloid; Male | 2015 |
[Effect of photodynamic therapy on the cell proliferation and collagen secretion of keloid fibroblasts].
Topics: Aminolevulinic Acid; Apoptosis; Cell Culture Techniques; Cell Proliferation; Collagen; Fibroblasts; | 2015 |
Evaluating an outreach service for paediatric burns follow up.
Topics: Adolescent; Aftercare; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Contracture; Cost-Ben | 2015 |
[A man with multiple erythematous and hyperpigmented papules].
Topics: Adult; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Male; Pressure; Treatment Outcome | 2015 |
The role of Duffy antigen receptor for chemokines in keloids.
Topics: Cell Movement; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Duffy Blood-Group System; Fibrob | 2015 |
Aspidin PB, a novel natural anti-fibrotic compound, inhibited fibrogenesis in TGF-β1-stimulated keloid fibroblasts via PI-3K/Akt and Smad signaling pathways.
Topics: Actins; Cell Survival; Cells, Cultured; Collagen Type I; Connective Tissue Growth Factor; Cyclohexan | 2015 |
EDA Fibronectin in Keloids Create a Vicious Cycle of Fibrotic Tumor Formation.
Topics: Animals; Ectodysplasins; Fibroblasts; Fibronectins; Gene Expression Regulation; Humans; Keloid | 2015 |
Genome-Wide Scan for Methylation Profiles in Keloids.
Topics: Case-Control Studies; CpG Islands; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; | 2015 |
Location of Keloids and Its Treatment Modality May Influence the Keloid Recurrence in Children.
Topics: Adolescent; Child; Face; Female; Humans; Injections, Intralesional; Keloid; Laser Therapy; Male; Nec | 2015 |
Fibulin-5 regulates keloid-derived fibroblast-like cells through integrin beta-1.
Topics: Adult; Extracellular Matrix Proteins; Female; Fibroblasts; Humans; Integrin beta1; Keloid; Male; Mid | 2016 |
Superimposed segmental morphea with keloidal features.
Topics: Adolescent; Female; Humans; Keloid; Scleroderma, Localized; Ultraviolet Therapy | 2015 |
Tanshinone IIA Inhibits Proliferation and Induces Apoptosis Through the Downregulation of Survivin in Keloid Fibroblasts.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Down-Regulation; Fibrob | 2016 |
Heat Shock Protein 90 Inhibitor (17-AAG) Induces Apoptosis and Decreases Cell Migration/Motility of Keloid Fibroblasts.
Topics: Apoptosis; Benzoquinones; Blotting, Western; Case-Control Studies; Cell Line; Cell Movement; Cell Pr | 2015 |
Altered circulating endothelial progenitor cells in patients with keloid.
Topics: Adolescent; Adult; Case-Control Studies; Child; Endothelial Progenitor Cells; Enzyme-Linked Immunoso | 2016 |
Keloid removal by shave excision with adjuvant external beam radiation therapy.
Topics: Adult; Dermatologic Surgical Procedures; Dose Fractionation, Radiation; Ear Auricle; Female; Humans; | 2015 |
Analysis of the Surgical Treatments of 63 Keloids on the Cartilaginous Part of the Auricle: Effectiveness of the Core Excision Method.
Topics: Ear Auricle; Ear Cartilage; Female; Humans; Keloid; Male; Plastic Surgery Procedures | 2015 |
Analysis of the Surgical Treatments of 63 Keloids on the Cartilaginous Part of the Auricle: Effectiveness of the Core Excision Method.
Topics: Ear Auricle; Ear Cartilage; Female; Humans; Keloid; Male; Plastic Surgery Procedures | 2015 |
Reply: Analysis of the Surgical Treatments of 63 Keloids on the Cartilaginous Part of the Auricle: Effectiveness of the Core Excision Method.
Topics: Ear Auricle; Ear Cartilage; Female; Humans; Keloid; Male; Plastic Surgery Procedures | 2015 |
Embedded tooth fragment masquerading as keloid for 11 months.
Topics: Adolescent; Diagnostic Errors; Foreign Bodies; Humans; Keloid; Lacerations; Lip; Male; Tooth Fractur | 2015 |
Preliminary Outcomes of Distal IMAP and SEAP Flaps for the Treatment of Unstable Keloids Subject to Recurrent Inflammation and Infections in the Lower Sternal and Upper Abdominal Areas.
Topics: Abdomen; Adult; Aged; Epigastric Arteries; Female; Humans; Inflammation; Keloid; Male; Mammary Arter | 2015 |
[In vitro study of TGF-β1-induced epithelial-mesenchymal transition of keloid epithelial cells].
Topics: Biomarkers; Cadherins; Epithelial Cells; Epithelial-Mesenchymal Transition; Humans; In Vitro Techniq | 2015 |
Hypofractionated electron-beam radiation therapy for keloids: retrospective study of 568 cases with 834 lesions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Dose Fractionation, Radiation; | 2015 |
Hepatocyte growth factor-expressing adenovirus upregulates matrix metalloproteinase-1 expression in keloid fibroblasts.
Topics: Adenoviridae; Adult; Cells, Cultured; Collagen Type I; Collagen Type II; Female; Fibroblasts; Geneti | 2016 |
A simplified three-dimensional volume measurement technique in keloid scars: Validity and reliability.
Topics: Computer Simulation; Equipment Design; Humans; Imaging, Three-Dimensional; Keloid; Reproducibility o | 2015 |
Immunohistochemical Evaluation of Leptin Expression in Wound Healing: A Clue to Exuberant Scar Formation.
Topics: Adolescent; Adult; Case-Control Studies; Cicatrix, Hypertrophic; Female; Humans; Immunohistochemistr | 2016 |
Cross-talk between TGF-β/Smad pathway and Wnt/β-catenin pathway in pathological scar formation.
Topics: Adult; Aged; beta Catenin; Blotting, Western; Case-Control Studies; Cells, Cultured; Cicatrix, Hyper | 2015 |
LTBP-2 Has a Single High-Affinity Binding Site for FGF-2 and Blocks FGF-2-Induced Cell Proliferation.
Topics: Binding Sites; Cell Line; Cell Proliferation; Fibrillins; Fibroblast Growth Factor 2; Fibroblasts; H | 2015 |
Dramatic hyperpigmentation of keloids after intralesional triamcinolone acetonide injection.
Topics: Diagnosis, Differential; Female; Glucocorticoids; Humans; Hyperpigmentation; Injections, Intralesion | 2015 |
Analysis of Characteristics Similar to Autoimmune Disease in Keloid Patients.
Topics: Adult; Antibodies, Antinuclear; Autoimmune Diseases; Biopsy, Needle; Case-Control Studies; Enzyme-Li | 2015 |
Foreign body reactions may not influence the keloid recurrence.
Topics: Body Piercing; Ear Auricle; Ear Diseases; Female; Foreign-Body Reaction; Humans; Keloid; Recurrence | 2016 |
The role of aldo-keto reductase 1C3 (AKR1C3)-mediated prostaglandin D2 (PGD2) metabolism in keloids.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Apoptosis; Caspase 3; Cell | 2016 |
Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model.
Topics: Benzoquinones; Biomarkers; Blotting, Western; Cells, Cultured; Collagen Type I; Collagen Type III; E | 2015 |
Role of chymase in the local renin-angiotensin system in keloids: inhibition of chymase may be an effective therapeutic approach to treat keloids.
Topics: Adolescent; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting E | 2015 |
Current Strategies in the Treatment of Scars and Keloids.
Topics: Antimetabolites, Antineoplastic; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Cryosurgery; Fluo | 2015 |
Ingenol mebutate treatment in keloids.
Topics: Diterpenes; Female; Humans; Keloid; Middle Aged | 2015 |
LncRNA expression profiles and validation in keloid and normal skin tissue.
Topics: Calcium Channels, T-Type; Gene Expression Regulation, Neoplastic; Humans; Keloid; Oligonucleotide Ar | 2015 |
Creation of a head and neck Keloid quality of life questionnaire.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Head; Humans; Keloid; Middle Aged; Neck; Prospective St | 2015 |
Treatment of keloid scars with a 1210-nm diode laser in an animal model.
Topics: Animals; Female; Humans; Keloid; Lasers, Semiconductor; Mice; Mice, Nude; Treatment Outcome; Wound H | 2015 |
Objective Assessment of the Precision, Accuracy, and Reliability of a Measurement Method for Keloid Scar Volume (PARKS Study).
Topics: Dental Impression Materials; Dimensional Measurement Accuracy; Ear Auricle; Healthy Volunteers; Huma | 2015 |
Hsp70 Knockdown by siRNA Decreased Collagen Production in Keloid Fibroblasts.
Topics: Adolescent; Adult; Blotting, Western; Collagen; Female; Fibroblasts; Gene Expression Regulation; HSP | 2015 |
Do Histopathologic Parameters Affect the Rate of Recurrence in Auricular Keloid Patients?
Topics: Adolescent; Adult; Age Factors; Collagen; Dermis; Ear Diseases; Ear, External; Epidermal Cyst; Femal | 2015 |
Efficacy of custom-made pressure clips for ear keloid treatment after surgical excision.
Topics: Adult; Ear Diseases; Ear, External; Equipment Design; Female; Follow-Up Studies; Humans; Keloid; Mal | 2016 |
Association of keloids with systemic medical conditions: a retrospective analysis.
Topics: Adult; Age Distribution; Aged; Case-Control Studies; Comorbidity; Female; Humans; Hypertension; Inci | 2016 |
NEDD4-1 and PTEN expression in keloid scarring.
Topics: Adolescent; Adult; Child; Endosomal Sorting Complexes Required for Transport; Female; Humans; Immuno | 2015 |
[Intralesional corticosteroid injections for pre-sternal keloids].
Topics: Anesthetics, Local; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Lidocaine; Male; Mid | 2015 |
Photodynamic Therapy-Induced Apoptosis of Keloid Fibroblasts is Mediated by Radical Oxygen Species In Vitro.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Apoptosis; Cell Division; Cells, Cultured; F | 2015 |
A novel regulatory function for miR-29a in keloid fibrogenesis.
Topics: Adolescent; Adult; Collagen Type I; Collagen Type III; Female; Fibroblasts; Humans; Keloid; Male; Mi | 2016 |
Successful eradication of helical rim keloids with surgical excision followed by pressure therapy using a combination of magnets and silicone gel sheeting.
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Female; Humans; Keloid; Magnetic Field Th | 2017 |
[Clinical observation the effect resection surgery by transferring the skin flap to repair the earlobe keloid].
Topics: Ear Diseases; Ear, External; Humans; Keloid; Surgical Flaps; Wound Healing | 2015 |
[Denucleated elevation treats auricle keloids].
Topics: Ear Auricle; Humans; Keloid | 2015 |
Extensive keloid formation after pemphigus vulgaris.
Topics: Adrenal Cortex Hormones; Aged; Dermatologic Agents; Drug Therapy, Combination; Humans; Keloid; Male; | 2015 |
Co-localization of LTBP-2 with FGF-2 in fibrotic human keloid and hypertrophic scar.
Topics: Adolescent; Adult; Binding Sites; Case-Control Studies; Cicatrix, Hypertrophic; Elastic Tissue; Elas | 2016 |
[The effect of Metformin on the proliferation and collagen synthesis of human keloids fibroblasts].
Topics: Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Fibroblasts; Forkhead Box Protein O1 | 2015 |
Keloid-derived, plasma/fibrin-based skin equivalents generate de novo dermal and epidermal pathology of keloid fibrosis in a mouse model.
Topics: Animals; Cells, Cultured; Collagen Type I; Dermis; Disease Models, Animal; Epidermal Cells; Fibrin; | 2016 |
Novel X-linked syndrome of cardiac valvulopathy, keloid scarring, and reduced joint mobility due to filamin A substitution G1576R.
Topics: Adult; Alleles; Amino Acid Substitution; Codon; Facies; Filamins; Genetic Association Studies; Genet | 2016 |
Case of syringomatous carcinoma with unique clinical presentation.
Topics: Biopsy; Carcinoma; Cicatrix, Hypertrophic; Diagnosis, Differential; Hand; Humans; Immunohistochemist | 2016 |
Increased blood flow in keloids and adjacent skin revealed by laser speckle contrast imaging.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Keloid; Lasers; Male; Middle Aged; Optical Imaging; | 2016 |
Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model.
Topics: Benzoquinones; Collagen Type I; Collagen Type III; Extracellular Matrix; Fibroblasts; HSP90 Heat-Sho | 2016 |
Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility.
Topics: Animals; Cell Movement; Cells, Cultured; Collagen Type VI; Epidermal Cells; Epidermis; Extracellular | 2016 |
[History of keloid].
Topics: History, 18th Century; History, 19th Century; History, 20th Century; History, Medieval; Humans; Kelo | 2016 |
Solanidine and tomatidine trigger scar pruritus.
Topics: Administration, Cutaneous; Adult; Aged; Burns; Cicatrix, Hypertrophic; Diosgenin; Female; Humans; Ke | 2016 |
Central regions of keloids are severely ischaemic.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Fibroblasts; Human | 2016 |
Another Piece in the Fibrotic Puzzle: TSLP as a Novel Ligand for Fibrocyte Activation.
Topics: Animals; Collagen; Cytokines; Female; Fibroblasts; Humans; Keloid; Receptors, CXCR4 | 2016 |
HSP90 and TLR4 Interplay in Keloids.
Topics: Apoptosis; Benzoquinones; Cell Movement; Fibroblasts; HSP90 Heat-Shock Proteins; Humans; Keloid; Lac | 2016 |
Reply: Heat Shock Protein 90 Inhibitor (17-AAG) Induces Apoptosis and Decreases Cell Migration Motility of Keloid Fibroblasts.
Topics: Apoptosis; Benzoquinones; Cell Movement; Fibroblasts; HSP90 Heat-Shock Proteins; Humans; Keloid; Lac | 2016 |
TSLP Is a Potential Initiator of Collagen Synthesis and an Activator of CXCR4/SDF-1 Axis in Keloid Pathogenesis.
Topics: Animals; Blotting, Western; Cells, Cultured; Chemokine CXCL12; Collagen; Cytokines; Disease Models, | 2016 |
IL-6 Polymorphism and Susceptibility to Keloid Formation in a Japanese Population.
Topics: Asian People; Case-Control Studies; Confidence Intervals; Female; Genetic Predisposition to Disease; | 2016 |
Bilateral gigantic earlobe keloids.
Topics: Aged, 80 and over; Body Piercing; Ear, External; Female; Humans; Keloid | 2016 |
Perioperative Interstitial High-Dose-Rate Brachytherapy for the Treatment of Recurrent Keloids: Feasibility and Early Results.
Topics: Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Brachytherapy; Feasibility Studies; Female; | 2016 |
Spatial distribution of filament elasticity determines the migratory behaviors of a cell.
Topics: Actins; Animals; Cell Line; Cell Movement; Cell Polarity; Elasticity; Fibroblasts; Humans; Keloid; M | 2016 |
A New Approach in the Treatment of Keloids: UVA-1 Laser.
Topics: Adult; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Ultraviolet Rays | 2016 |
Polarized Microscopy in Lesions With Altered Dermal Collagen.
Topics: Biomarkers, Tumor; Biopsy; Dermatofibrosarcoma; Diagnosis, Differential; Fibrillar Collagens; Histio | 2016 |
Chemokine-Like Factor 1 (CKLF-1) is Overexpressed in Keloid Patients: A Potential Indicating Factor for Keloid-Predisposed Individuals.
Topics: Adolescent; Adult; Case-Control Studies; Chemokines; Cicatrix; Female; Genetic Predisposition to Dis | 2016 |
A Novel Approach to Keloid Reconstruction with Bilaminar Dermal Substitute and Epidermal Skin Grafting.
Topics: Epidermis; Female; Humans; Keloid; Male; Plastic Surgery Procedures; Skin Transplantation; Skin, Art | 2016 |
Causal network analysis of head and neck keloid tissue identifies potential master regulators.
Topics: Aminopyridines; Case-Control Studies; CpG Islands; Cyclic GMP-Dependent Protein Kinase Type II; DNA | 2016 |
[Treatment of ear keloids by striping combined with asiaticoside ointment and triamcinolone acetonide].
Topics: Ear, External; Humans; Keloid; Triamcinolone Acetonide; Triterpenes | 2015 |
The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Culture Media, Conditioned; Epidermis; Fibroblasts; Fibros | 2016 |
Possible way for reduction of reported catastrophic blindness due to injection of steroid in the treatment of keloid scar.
Topics: Blindness; Humans; Injections, Intralesional; Keloid; Steroids | 2016 |
Expression of embryonic stem cell markers in keloid-associated lymphoid tissue.
Topics: Embryonic Stem Cells; Female; Humans; Immunohistochemistry; Keloid; Lymphoid Tissue; Male; Nanog Hom | 2016 |
Stress chaperone mortalin regulates human melanogenesis.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Diglycerides; HSP70 Heat-Shock Proteins; Humans; Hy | 2016 |
Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-β2 by targeting ZNF217 via miR-200c in keloid fibroblasts.
Topics: Biomarkers; Down-Regulation; Fibroblasts; Gene Knockdown Techniques; Humans; Keloid; MicroRNAs; RNA, | 2016 |
Serum miRNAs Signature Plays an Important Role in Keloid Disease.
Topics: Adolescent; Adult; Computational Biology; Down-Regulation; Female; Gene Expression Profiling; Humans | 2016 |
Multiple asymptomatic cutaneous pilar leiomyoma versus spontaneous eruptive keloids - a case report.
Topics: Adolescent; Humans; Keloid; Leiomyoma; Male; Skin Neoplasms | 2016 |
Transforming Growth Factor Beta Gene Signatures are Spatially Enriched in Keloid Tissue Biopsies and Ex vivo-Cultured Keloid Fibroblasts.
Topics: Biopsy; Cells, Cultured; Computational Biology; Fibroblasts; Gene Expression; Humans; Keloid; Princi | 2017 |
[The observation of therapeutic effect of auricle keloid by the operation of through resection].
Topics: Ear Auricle; Humans; Keloid; Otologic Surgical Procedures | 2016 |
[Whole-genome sequencing on one case of Han familial keloids].
Topics: China; Genome, Human; Humans; Keloid; Mutation; Pedigree; Polymorphism, Single Nucleotide; Sequence | 2016 |
[Keloid scars (part II): Treatment and prevention].
Topics: Bleomycin; Cicatrix, Hypertrophic; Dermatologic Agents; Glucocorticoids; Humans; Injections, Intrale | 2017 |
Bone marrow derived mesenchymal stem cells inhibit the proliferative and profibrotic phenotype of hypertrophic scar fibroblasts and keloid fibroblasts through paracrine signaling.
Topics: Adolescent; Adult; Bone Marrow Cells; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; C | 2016 |
DLQI and POSAS Scores in Keloid Patients.
Topics: Adult; Combined Modality Therapy; Cryotherapy; Female; Glucocorticoids; Humans; Injections, Intrales | 2016 |
Three-dimensional imaging for volume measurement of hypertrophic and keloid scars, reliability of a previously validated simplified technique in clinical setting.
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Equipment Design; Equipment Failure Analysis | 2016 |
Keloid Management: A Retrospective Case Review on a New Approach Using Surgical Excision, Platelet-Rich Plasma, and In-office Superficial Photon X-ray Radiation Therapy.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Cohort Studies; Combined Modality Therapy; Esthetics; Fema | 2016 |
Biological significance of genome-wide DNA methylation profiles in keloids.
Topics: CpG Islands; DNA Methylation; Gene Expression Profiling; Humans; Keloid; Prospective Studies; Signal | 2017 |
Top 10 Facts You Need to Know about About Keloids and Their Treatment.
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Compression Bandages; Cryotherapy; Diagnosis, Dif | 2016 |
Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways.
Topics: Adult; Cell Cycle; Cell Movement; Cell Proliferation; Cells, Cultured; Female; Fibroblasts; Humans; | 2016 |
[External branch spinal nerve paralysis on keloid scar].
Topics: Humans; Keloid; Male; Pain; Paralysis; Plastic Surgery Procedures; Spinal Nerves; Young Adult | 2016 |
Keloids and Hypertrophic Scars: Pathophysiology, Classification, and Treatment.
Topics: Algorithms; Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Wound Healing | 2017 |
Increased epidermal thickness and abnormal epidermal differentiation in keloid scars.
Topics: Adolescent; Adult; Biomarkers; Biopsy; Cell Differentiation; Cells, Cultured; Cicatrix, Hypertrophic | 2017 |
Burden of Keloid Disease: A Cross-sectional Health-related Quality of Life Assessment.
Topics: Adolescent; Adult; Cross-Sectional Studies; Elasticity; Emotions; Female; Humans; Keloid; Male; Midd | 2017 |
[The combined treatment of auricular keloid with multi-function electric ion surgery].
Topics: Combined Modality Therapy; Ear, External; Humans; Keloid | 2016 |
Observational retrospective study evaluating the effects of oral isotretinoin in keloids and hypertrophic scars.
Topics: Acne Vulgaris; Administration, Oral; Adolescent; Adult; Case-Control Studies; Cicatrix, Hypertrophic | 2016 |
Identification of a Potential Molecular Diagnostic Biomarker in Keloid Disease: Syndecan-1 (CD138) Is Overexpressed in Keloid Scar Tissue.
Topics: Biomarkers; Cicatrix, Hypertrophic; Dermatofibrosarcoma; Enzyme-Linked Immunosorbent Assay; Humans; | 2016 |
Establishment of Patient-Derived Keloid Xenograft Model.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Fibroblasts; Heterografts; Humans; Keloid; Male; M | 2016 |
Pleiotrophin is downregulated in human keloids.
Topics: Adolescent; Adult; Carrier Proteins; Cells, Cultured; Child; Cytokines; Down-Regulation; Fibroblasts | 2016 |
Genetic association of the COL1A1 gene promoter -1997 G/T (rs1107946) andSp1 +1245 G/T (rs1800012) polymorphisms and keloid scars in a Jeddah population.
Topics: Case-Control Studies; Collagen Type I; Collagen Type I, alpha 1 Chain; Female; Gene Frequency; Genet | 2016 |
Silencing NLRC5 inhibits extracellular matrix expression in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway.
Topics: Cell Proliferation; Collagen Type I; Extracellular Matrix; Fibroblasts; Gene Silencing; Humans; Intr | 2016 |
Assessment of the Combined Efficacy of Needling and the Use of Silicone Gel in the Treatment of C-Section and Other Surgical Hypertrophic Scars and Keloids.
Topics: Administration, Topical; Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Cosmetic Techniqu | 2016 |
Surgical Excision and Adjuvant Brachytherapy vs External Beam Radiation for the Effective Treatment of Keloids: 10-Year Institutional Retrospective Analysis.
Topics: Adolescent; Adult; Aged; Brachytherapy; Child; Dermatologic Surgical Procedures; Female; Humans; Kap | 2017 |
TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21.
Topics: Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Fibroblasts; Humans; Keloid; Matrix | 2016 |
Keloids, Spontaneous or After Minor Skin Injury: Importance of Not Missing Bethlem Myopathy.
Topics: Adolescent; Collagen Type VI; Contracture; Female; Humans; Keloid; Male; Middle Aged; Muscular Dystr | 2017 |
[Not Available].
Topics: Humans; Keloid; Male; Paralysis; Plastic Surgery Procedures; Spinal Nerves; Young Adult | 2016 |
Algorithm of chest wall keloid treatment.
Topics: Adult; Algorithms; Asian People; Female; Humans; Keloid; Male; Middle Aged; Patient Reported Outcome | 2016 |
Water-filtered near-infrared influences collagen synthesis of keloid-fibroblasts in contrast to normal foreskin fibroblasts.
Topics: Cell Line; Collagen Type I; Fibroblasts; Foreskin; Humans; Infant; Infrared Rays; Keloid; Male; Temp | 2016 |
MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes.
Topics: Aldehyde Dehydrogenase 1 Family; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epi | 2016 |
Expressions of Collagen I and III in Hypoxic Keloid Tissue.
Topics: Collagen Type I; Collagen Type III; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immu | 2016 |
Localization of MMP-9 in multinuclear giant cells in keloids after treatment with 5-fluorouracil with or without combination of cryotherapy and cryotherapy alone.
Topics: Cryotherapy; Female; Fluorouracil; Humans; Keloid; Male; Matrix Metalloproteinase 9 | 2017 |
Beta-catenin causes fibrotic changes in the extracellular matrix via upregulation of collagen I transcription.
Topics: beta Catenin; Collagen Type I; Collagen Type II; Extracellular Matrix; Fibroblasts; Humans; Keloid; | 2017 |
Risk factors of keloids in Syrians.
Topics: Adolescent; Adult; Age Distribution; Aged; Child; Female; Humans; Incidence; Keloid; Male; Middle Ag | 2016 |
Upregulation of microRNA-205 suppresses vascular endothelial growth factor expression-mediated PI3K/Akt signaling transduction in human keloid fibroblasts.
Topics: Adolescent; Adult; Cell Line; Cell Survival; Child, Preschool; Chromones; Female; Fibroblasts; Human | 2017 |
A Recalcitrant Keloid Successfully Treated With CO2 Laser and Indocyanine Green Photodynamic Therapy.
Topics: Aged; Combined Modality Therapy; Humans; Indocyanine Green; Keloid; Lasers, Gas; Male; Photochemothe | 2017 |
Objective Spectrometric Measurement of Keloid Color in the East Asian Population: Pitfalls of Subjective Color Measurements.
Topics: Adolescent; Adult; Asia, Eastern; Asian People; Erythema; Female; Humans; Keloid; Male; Melanins; Mi | 2016 |
Sevoflurane-induced arrhythmia in healthy adult.
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Calcium; Humans; Ion Channels; Keloid; Male; | 2016 |
miR-21 promotes collagen production in keloid via Smad7.
Topics: Adult; Blotting, Western; Case-Control Studies; Collagen Type I; Collagen Type I, alpha 1 Chain; Col | 2017 |
The Keloid Scars of Slavery.
Topics: Black or African American; Enslavement; Female; History, 19th Century; Humans; Keloid; Literature, M | 2016 |
Lipid nano-bubble combined with ultrasound for anti-keloids therapy.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fenretinide; Fibroblasts; H | 2018 |
Delayed Innovations in Keloid Reconstruction.
Topics: Humans; Keloid | 2017 |
Reply: A Novel Approach to Keloid Reconstruction with Bilaminar Dermal Substitute and Epidermal Skin Grafting.
Topics: Epidermis; Fibroblasts; Humans; Keloid; Skin; Skin Transplantation; Skin, Artificial | 2017 |
Objective and subjective treatment evaluation of scars using optical coherence tomography, sonography, photography, and standardised questionnaires.
Topics: Adult; Aged; Cicatrix, Hypertrophic; Cryotherapy; Female; Humans; Injections, Intralesional; Keloid; | 2016 |
Wnt/β-Catenin Signaling Exacerbates Keloid Cell Proliferation by Regulating Telomerase.
Topics: Animals; Apoptosis; beta Catenin; Cell Proliferation; Epithelial-Mesenchymal Transition; Gene Expres | 2016 |
Treatment of Keloids With Excision and Adjuvant Radiation: A Single Center Experience and Review of the Literature.
Topics: Dermatologic Surgical Procedures; Female; Follow-Up Studies; Humans; Keloid; Male; Radiotherapy, Adj | 2017 |
Measurements of scar properties by SkinFibroMeter
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans; Injections, | 2017 |
An atypical foot infection.
Topics: Antifungal Agents; Diabetic Foot; Foot; Glucocorticoids; Humans; Keloid; Male; Middle Aged; Scedospo | 2016 |
Corneal keloid: four case reports of clinicopathological features and surgical outcome.
Topics: Adolescent; Amnion; Child, Preschool; Corneal Diseases; Humans; Keloid; Keratoplasty, Penetrating; M | 2016 |
S100A12 Induced in the Epidermis by Reduced Hydration Activates Dermal Fibroblasts and Causes Dermal Fibrosis.
Topics: Animals; Cell Culture Techniques; Cell Line, Tumor; Cicatrix, Hypertrophic; Coculture Techniques; Cu | 2017 |
Growth Differentiation Factor-9 Promotes Fibroblast Proliferation and Migration in Keloids through the Smad2/3 Pathway.
Topics: Adult; Cell Movement; Cell Proliferation; Cyclooxygenase 2; Female; Fibroblasts; Gene Silencing; Gro | 2016 |
Can subphysiological cold application be utilized in excessive dermal scarring prophylaxis and treatment?: A promising hypothetical perspective.
Topics: Animals; Burns; Cold Temperature; Cryotherapy; Dogs; Humans; Inflammation; Keloid; Models, Theoretic | 2016 |
A Role for Neuregulin-1 in Promoting Keloid Fibroblast Migration via ErbB2-mediated Signaling.
Topics: Case-Control Studies; Cell Movement; Cells, Cultured; Cytokines; Fibroblasts; Focal Adhesion Kinase | 2017 |
Endothelial cell-derived endothelin-1 is involved in abnormal scar formation by dermal fibroblasts through RhoA/Rho-kinase pathway.
Topics: Cell Differentiation; Cicatrix, Hypertrophic; Collagen Type I; Endothelial Cells; Endothelin-1; Fibr | 2017 |
[Study of the correlation between the expression of angiotensin Ⅱ and its receptors and collagen deposition in human keloid].
Topics: Angiotensin II; Animals; Collagen; Fibroblasts; Humans; Keloid; Receptor, Angiotensin, Type 1; Recep | 2016 |
TGF-β1 Induces Polypyrimidine Tract-Binding Protein to Alter Fibroblasts Proliferation and Fibronectin Deposition in Keloid.
Topics: Animals; Cell Proliferation; Cytokines; Female; Fibroblasts; Fibronectins; Heterografts; Humans; Kel | 2016 |
Hypoxia drives the transition of human dermal fibroblasts to a myofibroblast-like phenotype via the TGF-β1/Smad3 pathway.
Topics: Adult; Cell Hypoxia; Dermis; Fibrosis; Fluorescent Antibody Technique; Humans; Hypoxia-Inducible Fac | 2017 |
MiR-181a Targets PHLPP2 to Augment AKT Signaling and Regulate Proliferation and Apoptosis in Human Keloid Fibroblasts.
Topics: Apoptosis; Base Sequence; Cell Proliferation; DNA; Fibroblasts; Gene Expression Profiling; Humans; K | 2016 |
Inhibition of collagen synthesis by IWR-1 in normal and keloid-derived skin fibroblasts.
Topics: Adult; Aged; Cells, Cultured; Collagen; Collagenases; Enzyme Induction; Female; Fibroblasts; Humans; | 2017 |
3D modeling of keloid scars in vitro by cell and tissue engineering.
Topics: Cell Proliferation; Cells, Cultured; Collagen; Fibroblasts; Gels; Humans; Keloid; Kinetics; Male; Mi | 2017 |
Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans.
Topics: Black or African American; Cell Differentiation; Chondrogenesis; Connective Tissue; Gene Expression | 2017 |
Endothelial dysfunction may play a key role in keloid and hypertrophic scar pathogenesis - Keloids and hypertrophic scars may be vascular disorders.
Topics: Adrenal Cortex Hormones; Burns; Cell Movement; Cicatrix, Hypertrophic; Disease Progression; Endothel | 2016 |
Keloid progression: a stiffness gap hypothesis.
Topics: Elasticity; Humans; Keloid; Skin Diseases; Wound Healing; Wounds and Injuries | 2017 |
Strategy for Successful Management of Facial Keloid Using Triamcinolone Injection as Adjunct to Surgery.
Topics: Chemotherapy, Adjuvant; Dermatologic Surgical Procedures; Face; Glucocorticoids; Humans; Injections, | 2016 |
Introduction to Special Issue on Hypertrophic Scars and Keloids.
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Wound Healing | 2017 |
A Comparison of Gene Expression of Decorin and MMP13 in Hypertrophic Scars Treated With Calcium Channel Blocker, Steroid, and Interferon: A Human-Scar-Carrying Animal Model Study.
Topics: Adolescent; Adult; Animals; Burns; Calcium Channel Blockers; Child; Child, Preschool; Cicatrix; Cica | 2017 |
A Novel Approach to Keloid Reconstruction with Bilaminar Dermal Substitute and Epidermal Skin Grafting.
Topics: Epidermis; Fibroblasts; Humans; Keloid; Skin; Skin Transplantation; Skin, Artificial | 2017 |
Delayed allergic dermatitis presenting as a keloid-like reaction caused by sting from an Indo-Pacific Portuguese man-o'-war (Physalia utriculus).
Topics: Animals; Biopsy; Bites and Stings; Dermatitis, Atopic; Humans; Hydrozoa; Keloid; Male; Time Factors; | 2017 |
Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders: Implications for Targeted Inhibition.
Topics: beta Catenin; Cicatrix; Cicatrix, Hypertrophic; Glycogen Synthase Kinase 3 beta; Hedgehog Proteins; | 2016 |
The effect of moisturizers or creams on scars: a systematic review protocol.
Topics: Humans; Keloid; Skin Cream; Systematic Reviews as Topic; Treatment Outcome | 2017 |
Association of plasminogen activator inhibitor-1 and vitamin D receptor expression with the risk of keloid disease in a Chinese population.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asian People; Biomarkers; Case-Control Studies; Child; F | 2017 |
β-Adrenergic Receptor Blockers Reduce the Occurrence of Keloids and Hypertrophic Scars after Cardiac Device Implantation: A Single-Institution Case-Control Study.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Cardiac Resynchronization Therapy Devices; Cas | 2017 |
Inhibition of collagen production by ICG-001, a small molecule inhibitor for Wnt/β-catenin signaling, in skin fibroblasts.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Cicatrix, Hypertrophic; Collagen; Drug Evaluation, Preclini | 2017 |
Expression Profile of Long Noncoding RNAs in Human Earlobe Keloids: A Microarray Analysis.
Topics: Adult; Ear, External; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Keloid; | 2016 |
TIEG1 Represses Smad7-Mediated Activation of TGF-β1/Smad Signaling in Keloid Pathogenesis.
Topics: Adolescent; Adult; Case-Control Studies; Collagen; Down-Regulation; Early Growth Response Transcript | 2017 |
Adverse Effects and Surgical Complications in Pediatric Patients Undergoing Vagal Nerve Stimulation for Drug-Resistant Epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cough; Drug Resistant Epilepsy; Female; Humans | 2017 |
Sulforaphane suppresses cell growth and collagen expression of keloid fibroblasts.
Topics: Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen; Extracellular Matrix; Fibroblasts; | 2017 |
Discussion: Identification of Key Modules and Hub Genes of Keloids with Weighted Gene Coexpression Network Analysis.
Topics: Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Gene Expression Regulation, | 2017 |
Identification of Key Modules and Hub Genes of Keloids with Weighted Gene Coexpression Network Analysis.
Topics: Gene Expression; Gene Regulatory Networks; Humans; Keloid; Microarray Analysis | 2017 |
Laser-assisted topical corticosteroid delivery for the treatment of keloids.
Topics: Adrenal Cortex Hormones; Adult; Combined Modality Therapy; Drug Delivery Systems; Female; Humans; In | 2017 |
Intratracheal Keloid.
Topics: Bronchopulmonary Dysplasia; Fatal Outcome; Humans; Infant; Intubation; Keloid; Male; Resuscitation; | 2017 |
Knockdown of IRF3 inhibits extracellular matrix expression in keloid fibroblasts.
Topics: Cell Proliferation; Down-Regulation; Extracellular Matrix; Fibroblasts; Gene Knockdown Techniques; H | 2017 |
Color Doppler Ultrasound Assessment of Activity in Keloids.
Topics: Adolescent; Adult; Female; Humans; Keloid; Male; Retrospective Studies; Ultrasonography, Doppler, Co | 2017 |
Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment.
Topics: Adolescent; Adult; Anesthesia; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans; Injections, | 2017 |
Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment.
Topics: Adolescent; Adult; Anesthesia; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans; Injections, | 2017 |
Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment.
Topics: Adolescent; Adult; Anesthesia; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans; Injections, | 2017 |
Vibration Anesthesia for Pain Reduction During Intralesional Steroid Injection for Keloid Treatment.
Topics: Adolescent; Adult; Anesthesia; Cicatrix, Hypertrophic; Female; Glucocorticoids; Humans; Injections, | 2017 |
Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology.
Topics: Biopsy; Collagen; Epidermis; Epithelial-Mesenchymal Transition; Fibroblasts; Gene Expression Profili | 2017 |
Nodular colloid milium mimicking keloid.
Topics: Diagnosis, Differential; Diagnostic Errors; Facial Dermatoses; Humans; Keloid; Lip; Male; Middle Age | 2017 |
Suppression of transforming growth factor-beta1 expression in keloids after cryosurgery.
Topics: Cryosurgery; Female; Humans; Immunohistochemistry; Keloid; Male; Middle Aged; Transforming Growth Fa | 2017 |
Should excised keloid scars be sent for routine histologic analysis?
Topics: Histology; Humans; Hypertrophy; Keloid; Unnecessary Procedures | 2008 |
Potential therapeutical effects of botulinum toxin type A in keloid management.
Topics: Botulinum Toxins, Type A; Humans; Keloid | 2008 |
[Radiotherapy for keloids and hypertrophic scars].
Topics: Cicatrix, Hypertrophic; Combined Modality Therapy; Humans; Keloid; Radiotherapy, Adjuvant | 2008 |
[Expression of periostin and the effect of hydrocortisone on it in human fibroblasts of scar].
Topics: Burns; Cell Adhesion Molecules; Cicatrix, Hypertrophic; Female; Fibroblasts; Humans; Hydrocortisone; | 2008 |
Treatment of hypertrophic scars and keloids using intense pulsed light (IPL).
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix, Hypertrophic; Cohort Studies; Esthetics; Femal | 2008 |
Association of HLA-DQA1 and DQB1 alleles with keloids in Chinese Hans.
Topics: Adolescent; Adult; Alleles; Asian People; Case-Control Studies; China; Female; Gene Frequency; Genet | 2008 |
Severe keloids caused by hydrogen cyanide injury: a case report.
Topics: Accidents, Occupational; Adult; Antidotes; Burns, Chemical; Humans; Hydrogen Cyanide; Hyperbaric Oxy | 2008 |
Poiseuille's law and large-bore needles: insights into the delivery of corticosteroid injections in the treatment of keloids.
Topics: Adrenal Cortex Hormones; Anesthetics, Local; Humans; Injections, Intralesional; Keloid; Needles; Pai | 2008 |
TGF-beta1 antisense therapy modulates expression of matrix metalloproteinases in keloid-derived fibroblasts.
Topics: Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Keloid; Matrix M | 2008 |
A nodule on the ear with unique histological features.
Topics: Carcinoma, Basal Cell; Ear, External; Humans; Keloid; Male; Middle Aged; Skin Neoplasms | 2008 |
Keloid and hypertrophic scarring may result from a mechanoreceptor or mechanosensitive nociceptor disorder.
Topics: Animals; Cicatrix, Hypertrophic; Disease Models, Animal; Humans; Keloid; Mechanoreceptors; Models, T | 2008 |
GenCLiP: a software program for clustering gene lists by literature profiling and constructing gene co-occurrence networks related to custom keywords.
Topics: Cluster Analysis; Databases, Bibliographic; Gene Expression Profiling; Gene Regulatory Networks; Gen | 2008 |
A very rare complication: keloid formation after circumcision, and its treatment.
Topics: Child; Circumcision, Male; Follow-Up Studies; Humans; Keloid; Male; Penile Diseases | 2008 |
Management of ear keloids.
Topics: Adrenal Cortex Hormones; Body Piercing; Combined Modality Therapy; Ear Diseases; Ear, External; Huma | 2008 |
Treatment of keloids with itraconazole.
Topics: Angiogenesis Inhibitors; Antifungal Agents; Cell Division; Cicatrix, Hypertrophic; Dermatomycoses; F | 2008 |
Spontaneous eruptive keloid-like cutaneous lesions in a renal transplant patient: a form of nephrogenic systemic fibrosis?
Topics: Biopsy, Needle; Diagnosis, Differential; Follow-Up Studies; Humans; Immunohistochemistry; Injections | 2009 |
[Activity detection and immunohistochemistry study on xanthine oxidase in pathological scars].
Topics: Adolescent; Adult; Antioxidants; Cicatrix, Hypertrophic; Female; Humans; Immunohistochemistry; Keloi | 2008 |
Nodular scleroderma: a report of 2 cases.
Topics: Adult; Anti-Inflammatory Agents; Arthralgia; Female; Humans; Keloid; Male; Middle Aged; Pericarditis | 2008 |
Clinical applications of the superior epigastric artery perforator (SEAP) flap: anatomical studies and preoperative perforator mapping with multidetector CT.
Topics: Aged; Aged, 80 and over; Breast Neoplasms; Epigastric Arteries; Esthetics; Female; Humans; Keloid; M | 2009 |
Collagen fibril formation. A new target to limit fibrosis.
Topics: Animals; Antibodies, Monoclonal; Bone Morphogenetic Protein 1; Bone Morphogenetic Proteins; Collagen | 2008 |
Skin of color education in dermatology residency programs: does residency training reflect the changing demographics of the United States?
Topics: Curriculum; Dermatology; Humans; Internship and Residency; Keloid; Melanosis; Population Surveillanc | 2008 |
[Variations of lipid peroxidation products and copper, zinc-superoxide dismutase in pathological scars].
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Copper; Female; Humans; Keloid; Lipid Peroxidation; Male; | 2008 |
The penetrative abilities of liposomal mithramycin in explanted keloids.
Topics: Epidermis; Humans; Keloid; Liposomes; Plicamycin; Protein Synthesis Inhibitors; Skin Absorption | 2009 |
Isolation and characterization of multipotent human keloid-derived mesenchymal-like stem cells.
Topics: Adult; Adult Stem Cells; Antigens, CD; Cell Differentiation; Cell Separation; Cells, Cultured; Cultu | 2008 |
[The relationship between RUNX3 gene mutation and keloid].
Topics: Adolescent; Adult; Core Binding Factor Alpha 3 Subunit; DNA; Female; Humans; Keloid; Male; Middle Ag | 2008 |
The possible mechanism underlying postoperative atrophy of hyperplastic scar.
Topics: Atrophy; Cicatrix, Hypertrophic; Humans; Keloid; Postoperative Complications | 2008 |
Intralesional cryosurgery for the treatment of hypertrophic scars and keloids following aesthetic surgery: the results of a prospective observational study.
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Cryosurgery; Female; Humans; Keloid; Male; Middle Aged; P | 2008 |
Gene expression profiling reveals alteration of caspase 6 and 14 transcripts in normal skin of keloid-prone patients.
Topics: Apoptosis; Biopsy; Black People; Case-Control Studies; Caspase 14; Caspase 6; Cicatrix; Cytokines; G | 2009 |
Keloids as a serious disease such as malignancy.
Topics: Humans; Keloid | 2008 |
A new corneal disease with recurrent erosive episodes and autosomal-dominant inheritance.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alleles; Child; Child, Preschool; Corneal Dystrophies, Heredi | 2008 |
Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts.
Topics: 14-3-3 Proteins; Animals; Collagen Type I; Connective Tissue Growth Factor; Cricetinae; Endothelins; | 2009 |
Keloidal basal cell carcinoma: not a distinctive clinicopathological entity.
Topics: Aged; Aged, 80 and over; Carcinoma, Basal Cell; Collagen; Female; Humans; Immunohistochemistry; Kelo | 2009 |
Adenoviral overexpression and small interfering RNA suppression demonstrate that plasminogen activator inhibitor-1 produces elevated collagen accumulation in normal and keloid fibroblasts.
Topics: Adenoviridae; Adolescent; Adult; Aged; Cells, Cultured; Collagen; Female; Fibroblasts; Humans; Keloi | 2008 |
Remodelling of keloid tissue into normal-looking skin.
Topics: Anesthetics, Local; Antimetabolites; Drug Administration Schedule; Drug Therapy, Combination; Female | 2008 |
Prostate-specific membrane antigen expression in regeneration and repair.
Topics: Barrett Esophagus; Blood Vessels; Endometrium; Female; Granulation Tissue; Humans; Immunohistochemis | 2008 |
Keloids; review with an aetiological study.
Topics: Keloid | 1948 |
For radium treatment of scar keloids.
Topics: Keloid | 1947 |
The treatment of keloids by irradiation and electrosurgery.
Topics: Diathermy; Electrosurgery; Humans; Keloid | 1948 |
The treatment of keloids at Radium-hemmet, 1921-1941.
Topics: Humans; Keloid; Radiotherapy; Radium | 1948 |
Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37.
Topics: Antimicrobial Cationic Peptides; Cathelicidins; Cells, Cultured; Collagen; Fibroblasts; Humans; Kelo | 2009 |
[Apoptosis of human keloid fibroblast induced by small interfering RNA-mediated CyclinD1 gene silencing].
Topics: Apoptosis; Cells, Cultured; Cyclin D1; Fibroblasts; Flow Cytometry; Gene Silencing; Humans; Keloid; | 2008 |
Decreased production of MCP-1 and MMP-2 by keloid-derived fibroblasts.
Topics: Cells, Cultured; Chemokine CCL2; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Interleukin | 2009 |
Surgical treatment of earlobe keloid with CO2 laser radiation: case report and clinical standpoints.
Topics: Adult; Ear; Female; Humans; Keloid; Lasers, Gas | 2008 |
Dermabond tissue adhesive versus Steri-Strips in unilateral cleft lip repair: an audit of infection and hypertrophic scar rates.
Topics: Cleft Lip; Cyanoacrylates; England; Follow-Up Studies; Humans; Infant; Keloid; Oral Surgical Procedu | 2008 |
Positive association of HLA-DRB1*15 with keloid disease in Caucasians.
Topics: Gene Frequency; Genetic Predisposition to Disease; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Keloid; | 2008 |
Keloid banding using suture ligature: a novel technique and review of literature.
Topics: Craniocerebral Trauma; Follow-Up Studies; Humans; Keloid; Ligation; Male; Middle Aged; Neck Injuries | 2008 |
[What grows there? Painless "bulb" on the great toe].
Topics: Diagnosis, Differential; Foot Dermatoses; Humans; Keloid; Male; Toes | 2008 |
Human mesenchymal stem cells may be involved in keloid pathogenesis.
Topics: Adolescent; Adult; Blotting, Western; Cell Differentiation; Cell Migration Assays; Cell Proliferatio | 2008 |
A report of an apparent new genetic syndrome consisting of joint contractures, keloids, large optic cup-to-disc ratio and renal stones.
Topics: Abnormalities, Multiple; Adult; Child; Contracture; Female; Humans; Joints; Keloid; Kidney Calculi; | 2008 |
Keloid formation after stapled haemorrhoidectomy causing anal stenosis: a rare complication.
Topics: Adult; Anus Diseases; Hemorrhoids; Humans; Intestinal Obstruction; Keloid; Male; Surgical Stapling | 2008 |
Cytokine profiling and Stat3 phosphorylation in epithelial-mesenchymal interactions between keloid keratinocytes and fibroblasts.
Topics: Cell Communication; Cell Proliferation; Cells, Cultured; Chemokines; Cytokines; Epithelial Cells; Fi | 2009 |
A spontaneous skin lesion.
Topics: Adult; Diagnosis, Differential; Female; Humans; Injections, Intralesional; Keloid; Steroids | 2008 |
Reduction of pain in the treatment of vascular lesions with a pulsed dye laser and pneumatic skin flattening.
Topics: Adult; Child; Humans; Intermittent Pneumatic Compression Devices; Keloid; Keratosis; Lasers, Dye; Lo | 2009 |
Plasma-cell-predominant B-cell pseudolymphoma.
Topics: Abscess; B-Lymphocytes; Dermis; Diabetes Mellitus, Type 2; Diagnostic Errors; Eosinophils; Facial De | 2008 |
[Relationship between mutation at 1 573 fragment of TNF receptor II gene and keloid].
Topics: Adolescent; Adult; Base Sequence; DNA; Exons; Female; Humans; Keloid; Male; Middle Aged; Point Mutat | 2008 |
Basic fibroblast growth factor: a potential new therapeutic tool for the treatment of hypertrophic and keloid scars.
Topics: Cell Culture Techniques; Cell Differentiation; Cicatrix; Dermis; Epidermal Growth Factor; Fibroblast | 2009 |
Postoperative strontium-90 brachytherapy in the prevention of keloids: results and prognostic factors.
Topics: Adolescent; Adult; Brachytherapy; Female; Humans; Keloid; Male; Middle Aged; Radiotherapy Dosage; Re | 2009 |
5-Fluorouracil treatment of problematic scars.
Topics: Adult; Antimetabolites; Cicatrix, Hypertrophic; Disease Progression; Female; Fluorouracil; Follow-Up | 2009 |
Treatment of recurrent earlobe keloids with surgery and high-dose-rate brachytherapy.
Topics: Brachytherapy; Ear; Humans; Keloid; Radiotherapy Dosage; Recurrence | 2009 |
[The expression of fibrillin 1 in pathologic scars and its significance].
Topics: Cicatrix, Hypertrophic; Fibrillin-1; Fibrillins; Humans; Keloid; Microfilament Proteins; RNA, Messen | 2008 |
Troglitazone suppresses transforming growth factor-beta1-induced collagen type I expression in keloid fibroblasts.
Topics: Adolescent; Adult; Blotting, Western; Chromans; Collagen Type I; Female; Fibroblasts; Fibrosis; Huma | 2009 |
Histologic analysis of keloids and hypertrophic scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid | 2009 |
[Correlation analysis between clinical phenotypes of keloids and polymorphism of p53 gene codon 72].
Topics: Adolescent; Adult; Apoptosis; Child; Codon; Female; Gene Frequency; Genes, p53; Genotype; Humans; Ke | 2008 |
Outpatient reconstruction using integra* and subatmospheric pressure.
Topics: Adult; Ambulatory Surgical Procedures; Atmospheric Pressure; Burns; Child; Child, Preschool; Chondro | 2009 |
[Effects of recombinant adenovirus-mediated double suicide genes on implanted human keloid: experiment with athymic mice].
Topics: Adenoviridae; Animals; Apoptosis; Female; Genes, Transgenic, Suicide; Genetic Therapy; Humans; Keloi | 2008 |
Successful treatment of earlobe keloids in the pediatric population.
Topics: Child; Combined Modality Therapy; Ear, External; Glucocorticoids; Humans; Keloid; Treatment Outcome; | 2009 |
Matrix metalloproteinase-2 and -9 activities in human keloids, hypertrophic and atrophic scars: a pilot study.
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Collagen; Enzyme Precursors; Female; Gelatinases; Humans; | 2009 |
Dose-response relationship and dose optimization in radiotherapy of postoperative keloids.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; | 2009 |
Chronologic change of the maximum dimension of Bacillus Calmette-Guerin-induced keloids.
Topics: Adolescent; Adult; Age of Onset; BCG Vaccine; Child; Disease Progression; Female; Humans; Keloid; Ma | 2009 |
Differential apoptosis markers in human keloids and hypertrophic scars fibroblasts.
Topics: Adult; Apoptosis; Biomarkers; Cells, Cultured; Cicatrix, Hypertrophic; Female; Fibroblasts; Humans; | 2009 |
Keloid scars arising in striae caused by bra straps.
Topics: Adult; Clothing; Female; Humans; Keloid; Shoulder | 2009 |
DLQI scores in patients with keloids and hypertrophic scars: a prospective case control study.
Topics: Adult; Case-Control Studies; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; Prospective Studi | 2009 |
Incidence of hypertrophic and keloid scars after N-butyl 2-cyanoacrylate tissue adhesive had been used to close parotidectomy wounds: a prospective study of 100 consecutive patients.
Topics: Adolescent; Adult; Aged; Cicatrix, Hypertrophic; Enbucrilate; Female; Humans; Incidence; Injections, | 2009 |
Pressure earring as an adjunct to surgical removal of earlobe keloids.
Topics: Combined Modality Therapy; Equipment Design; Humans; Jewelry; Keloid; Pressure | 2009 |
Low decorin expression along with inherent activation of ERK1,2 in ear lobe keloids.
Topics: Adolescent; Adult; Cells, Cultured; Collagen; Decorin; Ear Auricle; Extracellular Matrix Proteins; F | 2009 |
Effect of lidocaine tape on pain during intralesional injection of triamcinolone acetonide for the treatment of keloid.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Female; Humans; Injections, Intralesional; Kel | 2009 |
Treatment of a postburn keloid scar with topical captopril: report of the first case.
Topics: Administration, Topical; Adolescent; Angiotensin-Converting Enzyme Inhibitors; Burns; Captopril; Fem | 2009 |
A custom-made silicon mold for pressure therapy to ear keloids.
Topics: Casts, Surgical; Ear, External; Equipment Design; Humans; Keloid; Plastic Surgery Procedures; Pressu | 2009 |
Keloid scarring, but not Dupuytren's contracture, is associated with unexplained carotid atherosclerosis.
Topics: Aged; Carotid Artery Diseases; Dupuytren Contracture; Female; Humans; Keloid; Male; Middle Aged; Mul | 2009 |
[Intubation with an Airtraq of a 7-year-old child with severe cervical burned sequels].
Topics: Burns; Child; Cicatrix; Device Removal; Equipment Design; Humans; Intubation, Intratracheal; Keloid; | 2009 |
Nonlinear laser imaging of skin lesions.
Topics: Adult; Aged; Carcinoma, Basal Cell; Female; Humans; Keloid; Lasers; Male; Melanoma; Microscopy, Conf | 2008 |
An in situ and in vitro investigation for the transglutaminase potential in tissue engineering.
Topics: Animals; Biocompatible Materials; Biological Assay; Collagen; Drug Carriers; Glutamine; Humans; Isoe | 2010 |
Proliferative activity in fibrosing lung diseases: a comparative study of Ki-67 immunoreactivity in diffuse alveolar damage, bronchiolitis obliterans-organizing pneumonia, and usual interstitial pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cell Count; Cell Proliferation; Child; Child | 2009 |
Safe and less painful injection of triamcenolone acetonide into a keloid--a technique.
Topics: Anesthetics, Local; Bupivacaine; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Lidocai | 2010 |
Failure of imiquimod 5% cream to prevent recurrence of surgically excised trunk keloids.
Topics: Adjuvants, Immunologic; Administration, Topical; Adult; Aminoquinolines; Emollients; Female; Humans; | 2009 |
Keloidal granuloma faciale after CO2 laser treatment for melanocytic naevus.
Topics: Adult; Carbon Dioxide; Granuloma; Humans; Keloid; Laser Therapy; Male; Nevus, Pigmented | 2009 |
Hepatoma-derived growth factor and its role in keloid pathogenesis.
Topics: Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Dermis; Enzyme Activation; Epi | 2010 |
Radiotherapy treatment of keloid scars and other benign conditions: is there a need for a database of patients treated?
Topics: Combined Modality Therapy; Databases as Topic; Humans; Keloid; Neoplasms, Radiation-Induced | 2009 |
Promoted activation of matrix metalloproteinase (MMP)-2 in keloid fibroblasts and increased expression of MMP-2 in collagen bundle regions: implications for mechanisms of keloid progression.
Topics: Adult; Collagen; Enzyme Activation; Extracellular Matrix; Fibroblasts; Humans; Immunohistochemistry; | 2009 |
Eruptive keloids: spontaneous reactivation after 60 years.
Topics: Aged, 80 and over; Cicatrix; Diagnosis, Differential; Follow-Up Studies; Humans; Keloid; Lymphoma, T | 2009 |
Differential and exclusive diagnosis of diseases that resemble keloids and hypertrophic scars.
Topics: Adenoma, Pleomorphic; Adult; Cicatrix, Hypertrophic; Cystadenoma; Diagnosis, Differential; Folliculi | 2009 |
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in patients with different types of scars and keloids.
Topics: Adolescent; Adult; Burns; Case-Control Studies; Cicatrix, Hypertrophic; Cohort Studies; Female; Huma | 2010 |
Keloids treated with postoperative Iridium 192* brachytherapy: a retrospective study.
Topics: Brachytherapy; Female; Humans; Iridium Radioisotopes; Keloid; Male; Postoperative Care; Recurrence; | 2009 |
Keloidal atypical fibroxanthoma: a case series.
Topics: Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Diagnosis, Differe | 2009 |
Integra Artificial Skin for burn scar revision in adolescents and children.
Topics: Adolescent; Burns; Child; Chondroitin Sulfates; Cicatrix, Hypertrophic; Collagen; Esthetics; Female; | 2010 |
Keloid occurring in a tattoo after laser hair removal.
Topics: Adult; Hair Removal; Humans; Keloid; Laser Therapy; Male; Tattooing | 2009 |
The effectiveness of narrowband ultraviolet B on hypertrophic scar in a patient having an isomorphic phenomenon and vitiligo.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Male; Ultraviolet Therapy; Vitiligo; Young Adult | 2008 |
[Multiple recurrences of an earlobe keloid: treatments with carbon dioxide laser vaporization, cryotherapy and finally keloid resection].
Topics: Aged; Combined Modality Therapy; Cryotherapy; Ear, External; Female; Humans; Keloid; Laser Therapy; | 2009 |
Do postsurgical interventions optimize ultimate scar cosmesis.
Topics: Administration, Cutaneous; Biological Products; Cicatrix; Combined Modality Therapy; Cosmetic Techni | 2009 |
Discrimination of collagen in normal and pathological skin dermis through second-order susceptibility microscopy.
Topics: Collagen; Dermatology; Elasticity; Humans; Image Processing, Computer-Assisted; Keloid; Lasers; Micr | 2009 |
Images in HIV/AIDS. Keloid after herpes zoster in an HIV-infected person.
Topics: Acyclovir; Aged; Anti-HIV Agents; Antiviral Agents; Herpes Zoster; HIV Infections; Humans; Keloid; M | 2009 |
[Expression and function of sphingosine kinases 1 and 2 in human keloid fibroblasts].
Topics: Adolescent; Adult; Cells, Cultured; Female; Fibroblasts; Humans; Keloid; Male; Phosphotransferases ( | 2009 |
Perioperative interstitial brachytherapy for recurrent keloid scars.
Topics: Brachytherapy; Combined Modality Therapy; Humans; Intraoperative Period; Keloid; Recurrence; Retrosp | 2009 |
Trapeze-flap plasty: effective method for postburn neck contracture elimination.
Topics: Adolescent; Adult; Burns; Child; Contracture; Female; Follow-Up Studies; Humans; Keloid; Male; Middl | 2010 |
[Tumor source theory of keloid occurrence].
Topics: Humans; Keloid; Neoplasms; Skin | 2009 |
Unfolded protein response regulation in keloid cells.
Topics: DNA-Binding Proteins; Extracellular Matrix; Fibroblasts; Humans; Hypoxia; Keloid; Regulatory Factor | 2011 |
Topical tamoxifen therapy in hypertrophic scars or keloids in burns.
Topics: Administration, Topical; Burns; Cell Differentiation; Cell Line; Cell Proliferation; Cicatrix, Hyper | 2010 |
Description of familial keloids in five pedigrees: evidence for autosomal dominant inheritance and phenotypic heterogeneity.
Topics: Adult; Age of Onset; Black or African American; Caribbean Region; Female; Humans; Keloid; Male; Pedi | 2009 |
Keloids show regional distribution of proliferative and degenerate connective tissue elements.
Topics: Adolescent; Adult; Cell Proliferation; Child; Collagen; DNA; Extracellular Matrix; Female; Fibroblas | 2010 |
Information from your family doctor. Keloids: prevention and treatment.
Topics: Humans; Keloid | 2009 |
Keloidal and granular cell change in a series of 171 atypical fibroxanthomas.
Topics: Aged; Aged, 80 and over; Female; Histiocytoma; Humans; Keloid; Male; Middle Aged; Skin Neoplasms | 2010 |
[Therapeutic features of cheloid scars at the Dermatology Unit of Treichville Teaching Hospital, Abidjan-Côte d'Ivoire].
Topics: Adolescent; Adult; Aged; Child; Combined Modality Therapy; Cote d'Ivoire; Female; Hospitals, Teachin | 2009 |
Auricular keloids: treatment and results.
Topics: Anti-Inflammatory Agents; Combined Modality Therapy; Ear; Female; Humans; Keloid; Male; Retrospectiv | 2010 |
A 5-year-old girl with scarring.
Topics: Burns; Child Abuse; Child, Preschool; Diagnosis, Differential; Female; Humans; Keloid; Mandatory Rep | 2009 |
[Perioperative interstitial brachytherapy for recurrent keloid scars].
Topics: Adolescent; Adult; Aged; Brachytherapy; Esthetics; Female; Humans; Keloid; Male; Middle Aged; Periop | 2010 |
Keloid treatment: is there a role for acellular human dermis (Alloderm)?
Topics: Child; Collagen; Female; Follow-Up Studies; Glucocorticoids; Humans; Injections, Intralesional; Kelo | 2010 |
Lightning-strike granuloma.
Topics: Adult; Granuloma Annulare; Humans; Keloid; Lightning Injuries; Male | 2009 |
Targeted broadband ultraviolet B phototherapy improves disorders characterized by increased dermal matrix.
Topics: Adult; Cicatrix, Hypertrophic; Dose-Response Relationship, Radiation; Granuloma Annulare; Histiocyto | 2009 |
[Intensive intracorneal keloid formation in a case of Peters plus syndrome and in Peters anomaly with maximum manifestation].
Topics: Abnormalities, Multiple; Cataract; Cornea; Corneal Diseases; Eye Abnormalities; Female; Humans; Infa | 2010 |
About strawberry, crab claws, and the Sir James Black's invention. Hypothesis: can we battle keloids with propranolol?
Topics: Evidence-Based Medicine; Humans; Keloid; Models, Biological; Propranolol; Vasodilator Agents | 2010 |
Low-level laser irradiation (InGaAlP-660 nm) increases fibroblast cell proliferation and reduces cell death in a dose-dependent manner.
Topics: 3T3 Cells; Animals; Cell Death; Cell Proliferation; Cell Survival; Dose-Response Relationship, Radia | 2010 |
The histopathologic spectrum of regression in atypical fibroxanthoma.
Topics: Aged; Aged, 80 and over; Cheek; Female; Fibrosis; Head and Neck Neoplasms; Histiocytoma, Benign Fibr | 2010 |
A prospective study in children: Pre- and post-surgery use of vitamin E in surgical incisions.
Topics: Administration, Topical; Chi-Square Distribution; Child; Child, Preschool; Cicatrix; Cryptorchidism; | 2010 |
Scoring of collagen organization in healthy and diseased human dermis by multiphoton microscopy.
Topics: Algorithms; Anisotropy; Cicatrix; Collagen; Dermis; Humans; Image Processing, Computer-Assisted; In | 2010 |
Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts.
Topics: Analysis of Variance; Fibroblasts; Fluoroimmunoassay; Humans; Immunoblotting; Keloid; Mitogen-Activa | 2010 |
Role of vascular endothelial growth factor in keloids: a clinicopathologic study.
Topics: Adolescent; Adult; Child; Female; Humans; Keloid; Male; Middle Aged; Vascular Endothelial Growth Fac | 2009 |
[Expression of Smads in keloid scarring].
Topics: Adolescent; Adult; Female; Humans; Keloid; Male; Middle Aged; RNA, Messenger; Signal Transduction; S | 2009 |
[The interaction between secreted frizzled-related protein 2 and osteoblast-specific factor 2 in keloid].
Topics: Cell Line; Core Binding Factor Alpha 1 Subunit; Genetic Vectors; Humans; Keloid; Membrane Proteins; | 2009 |
[The effect of tunicamycin on Fas protein expression and its function in fibroblasts from hypertrophic scar and keloid].
Topics: Adolescent; Adult; Antibodies, Monoclonal; Apoptosis; Child; Cicatrix, Hypertrophic; fas Receptor; F | 2009 |
The pulsed-dye laser for treatment of cutaneous conditions.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Lasers, Dye; Port-Wine Stain; Rosacea; Skin Diseases; Telang | 2009 |
Kimura's disease mimicking an earlobe keloid.
Topics: Adult; Angiolymphoid Hyperplasia with Eosinophilia; Diagnosis, Differential; Ear Diseases; Ear, Exte | 2010 |
Telomere shortening may be associated with human keloids.
Topics: Adult; Blotting, Southern; Cells, Cultured; Female; Fibroblasts; Genetic Association Studies; Humans | 2009 |
Association of HLA-DRB1* and keloid disease in an Afro-Caribbean population.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Black People; Case-Control Studies; Child; Child, Presch | 2010 |
Elastic fiber assembly is disrupted by excessive accumulation of chondroitin sulfate in the human dermal fibrotic disease, keloid.
Topics: Adolescent; Adult; Aged; Child; Chondroitin Sulfates; Elastic Tissue; Female; Humans; Keloid; Male; | 2009 |
Treatment of a painful keloid with botulinum toxin type A.
Topics: Aged, 80 and over; Botulinum Toxins, Type A; Female; Humans; Keloid; Neuromuscular Agents; Pain | 2010 |
Tumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axis.
Topics: Adult; Animals; Cell Proliferation; Cell Separation; Cytokines; Fibroblasts; Humans; Inflammation; I | 2009 |
Question: Can you identify this condition? The most likely diagnosis is keloid.
Topics: Abdomen; Adult; Diagnosis, Differential; Female; Humans; Keloid; Postoperative Complications; Skin | 2009 |
Garlic extract as a novel addition to antikeloid armamentarium: an untested hypothesis.
Topics: Anti-Inflammatory Agents; Garlic; Humans; Keloid; Plant Extracts | 2009 |
Risk factors in pediatric dermatologic surgery.
Topics: Adolescent; Anesthesia, General; Child; Child, Preschool; Cicatrix; Dermatology; Esthetics; Female; | 2009 |
Association of HLA class I alleles with keloids in Chinese Han individuals.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; China; Disease Progression; DNA Mutational Analysi | 2010 |
Surgical gem: inverted contralateral ear digital photograph as a template during earlobe keloid reconstruction.
Topics: Ear, External; Humans; Keloid; Photography; Plastic Surgery Procedures; Preoperative Care | 2010 |
The influence of surgical excision margins on keloid prognosis.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Keloid; Male; Middle Aged; Prognosis; Recurrence; Yo | 2010 |
Visual and pathologic analyses of keloid growth patterns.
Topics: Adult; Biopsy; Female; Humans; Keloid; Male; Plastic Surgery Procedures; Severity of Illness Index | 2010 |
Treatment of earlobe keloids by extralesional excision combined with preoperative and postoperative "sandwich" radiotherapy.
Topics: Adolescent; Adult; Aged; Body Piercing; Child; Combined Modality Therapy; Ear, External; Female; Hum | 2010 |
Encapsuloma: a case report.
Topics: Aged; Arthroplasty, Replacement; Facial Neuralgia; Female; Fibrosis; Follow-Up Studies; Granuloma, F | 2010 |
Clinical improvement in the therapy of aural keloids.
Topics: Adolescent; Adult; Combined Modality Therapy; Ear Diseases; Female; Humans; Keloid; Male; Middle Age | 2009 |
Enhanced MCP-1 release by keloid CD14+ cells augments fibroblast proliferation: role of MCP-1 and Akt pathway in keloids.
Topics: Adolescent; Adult; Case-Control Studies; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Cocult | 2010 |
Postoperative pressure therapy of ear keloids using a custom-made methyl methacrylate stent.
Topics: Combined Modality Therapy; Humans; Keloid; Pressure; Prosthesis Design; Stents | 2010 |
Molecular mechanism of pulsed-dye laser in treatment of keloids: an in vitro study.
Topics: Adult; Antibodies, Monoclonal; Apoptosis; Cell Cycle; Cells, Cultured; Fibroblasts; Flow Cytometry; | 2010 |
Regenerative medicine: a surgeon's perspective.
Topics: Adult; Animals; Child; Cicatrix; Cicatrix, Hypertrophic; Connective Tissue Growth Factor; Female; Fe | 2010 |
The most current algorithms for the treatment and prevention of hypertrophic scars and keloids.
Topics: Adrenal Cortex Hormones; Algorithms; Bandages; Cicatrix, Hypertrophic; Combined Modality Therapy; Co | 2010 |
Comparative proteomic analysis between normal skin and keloid scar.
Topics: 14-3-3 Proteins; Adolescent; Adult; Biomarkers, Tumor; Blotting, Western; Electrophoresis, Gel, Two- | 2010 |
Vitamin C attenuates ERK signalling to inhibit the regulation of collagen production by LL-37 in human dermal fibroblasts.
Topics: Antimicrobial Cationic Peptides; Ascorbic Acid; Cathelicidins; Cells, Cultured; Collagen; Dermis; Ex | 2010 |
Absence of pathological scarring in the donor site of the scalp in burns: an analysis of 295 cases.
Topics: Adolescent; Adult; Aged; Alopecia; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Epitheliu | 2010 |
Cushing's syndrome and adrenal insufficiency after intradermal triamcinolone acetonide for keloid scars.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Child; Cushing Syndrome; Female; Glucocorticoids | 2010 |
Differential distribution of haematopoietic and nonhaematopoietic progenitor cells in intralesional and extralesional keloid: do keloid scars provide a niche for nonhaematopoietic mesenchymal stem cells?
Topics: Adult; Antigens, CD; Biomarkers; Biopsy; Female; Fluorescence; Hematopoietic Stem Cells; Humans; Kel | 2010 |
[Effects of interferon-gamma on the transforming growth factor beta/Smad pathway in keloid-derived fibroblasts].
Topics: Cells, Cultured; Fibroblasts; Humans; Interferon-gamma; Keloid; RNA, Messenger; Signal Transduction; | 2009 |
Transmylohyoid/Submental intubation: review, analysis, and refinements.
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Facial Bones; Female; Follow-Up Studies; Hum | 2010 |
Multiple keloids.
Topics: Humans; Keloid | 1947 |
Contribution to the study of chelos.
Topics: Drug Therapy; Keloid; Pharmaceutical Preparations | 1947 |
Multiple keloids in twin sisters.
Topics: Disease; Diseases in Twins; Female; Humans; Keloid; Siblings; Twins | 1947 |
The use of AlloDerm for coverage after keloid excision.
Topics: Collagen; Ear, External; Female; Humans; Keloid; Surgery, Plastic; Young Adult | 2010 |
Keloids.
Topics: Humans; Keloid | 1947 |
Use of colchicine to prevent recurrence of ear keloids. A new approach.
Topics: Adult; Colchicine; Dose-Response Relationship, Drug; Ear Auricle; Female; Follow-Up Studies; Gout Su | 2010 |
Syndecan-2 and decorin: proteoglycans with a difference--implications in keloid pathogenesis.
Topics: Analysis of Variance; Blotting, Western; Coculture Techniques; Decorin; Down-Regulation; Extracellul | 2010 |
In vitro and in vivo evidence of pathogenic roles of Hic-5/ARA55 in keloids through Smad pathway and profibrotic transcription.
Topics: Adult; Aged; Aged, 80 and over; DNA Primers; Female; Fibroblasts; Gene Expression Regulation; Humans | 2010 |
The role of full-thickness skin grafting and steroid injection in the treatment of auricular keloids.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Combined Modality Therapy; Ear, External; Female; Human | 2010 |
[Surgical treatment of relapsing keloid of the pinna by fillet flap].
Topics: Adult; Aged; Ear Auricle; Female; Humans; Keloid; Male; Middle Aged; Recurrence; Surgical Flaps; You | 2010 |
Earlobe keloids: a novel and elegant surgical approach.
Topics: Body Piercing; Ear Neoplasms; Ear, External; Glucocorticoids; Humans; Keloid; Otorhinolaryngologic S | 2010 |
Letter: further options for treatment of hypertrophic scars and keloids.
Topics: Adrenal Cortex Hormones; Bleomycin; Cicatrix, Hypertrophic; Cryosurgery; Humans; Keloid; Laser Thera | 2010 |
Effect of the abrogation of TGF-beta1 by antisense oligonucleotides on the expression of TGF-beta-isoforms and their receptors I and II in isolated fibroblasts from keloid scars.
Topics: Cell Separation; Cytokines; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gene Expression Regulati | 2010 |
Reducing scar formation after lip repair by injecting botulinum toxin.
Topics: Botulinum Toxins, Type A; Cleft Lip; Humans; Injections, Intralesional; Keloid; Lip | 2010 |
The aging African-American face.
Topics: Alopecia; Black or African American; Blepharoplasty; Botulinum Toxins, Type A; Chemexfoliation; Derm | 2010 |
Does over-expression of transforming growth factor-beta account for the increased morbidity in African-Americans?: possible clinical study and therapeutic implications.
Topics: Black People; Female; Glaucoma; Heart Transplantation; Humans; Keloid; Leiomyoma; Male; Sarcoidosis; | 2010 |
[Impact of TGF-beta1 antisense on collagen-binding integrins in keloid].
Topics: Collagen; Fibroblasts; Humans; Immunoenzyme Techniques; Integrins; Keloid; Oligonucleotides, Antisen | 2010 |
Use of a collagen-glycosaminoglycan copolymer (Integra) in combination with adjuvant treatments for reconstruction of severe chest keloids.
Topics: Adult; Aged; Anti-Inflammatory Agents; Chondroitin Sulfates; Chronic Disease; Collagen; Combined Mod | 2010 |
[Study on the inhibitory effect of ALA-PDT on the proliferation of fibroblasts from keloid].
Topics: Aminolevulinic Acid; Cell Proliferation; Cells, Cultured; Fibroblasts; Humans; Keloid; Lasers; Photo | 2010 |
Keloidal and other collagen patterns in atypical fibroxanthomas.
Topics: Adult; Aged; Collagen; Female; Histiocytoma, Benign Fibrous; Humans; Keloid; Male; Skin Neoplasms | 2010 |
Keloidal and verrucous lesions in an Amerindian patient.
Topics: Dermatomycoses; Humans; Keloid; Male; Middle Aged; Warts | 2010 |
Association of HLA-DRB1 alleles with keloids in Chinese Han individuals.
Topics: Adolescent; Adult; Aged; Alleles; Asian People; Child; Child, Preschool; Female; HLA-DR Antigens; HL | 2010 |
Pressure earring as an adjunct to surgical removal of earlobe keloids.
Topics: Ear, External; Follow-Up Studies; Humans; Keloid; Plastic Surgery Procedures; Pressure; Treatment Ou | 2010 |
Aldosterone and mineralocorticoid receptor antagonists modulate elastin and collagen deposition in human skin.
Topics: Adult; Aldosterone; Biopsy; Cells, Cultured; Cicatrix; Collagen Type I; Elasticity; Elastin; Epleren | 2010 |
[Expression of mast cell tryptase in scar].
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Humans; Keloid; RNA, Messenger; Skin; Tryptases; Young Ad | 2010 |
Differential expression of growth differentiation factor-9 in keloids.
Topics: Adolescent; Adult; Blotting, Western; Cells, Cultured; Cicatrix, Hypertrophic; Female; Fibroblasts; | 2010 |
Full-thickness skin grafting with marginal deepithelialization of the defect for reconstruction of helical rim keloids.
Topics: Adolescent; Adult; Child; Ear, External; Esthetics; Female; Graft Survival; Humans; Keloid; Male; Sk | 2010 |
Epigenetically altered wound healing in keloid fibroblasts.
Topics: Acetylation; Azacitidine; Black or African American; Cell Division; Cells, Cultured; Culture Media; | 2010 |
Immunohistochemical expression of TGF-β1 in keloids and hypertrophic scars.
Topics: Adolescent; Adult; Child; Cicatrix, Hypertrophic; Female; Humans; Immunohistochemistry; Keloid; Male | 2011 |
Effect of transforming growth factor-beta1 antisense oligonucleotides on matrix metalloproteinases and their inhibitors in keloid fibroblasts.
Topics: Case-Control Studies; Cell Culture Techniques; Cross-Sectional Studies; Fibroblasts; Humans; Keloid; | 2010 |
Electrochemotherapy treatment of a recalcitrant earlobe keloid scar with chronic lymphocytic leukaemia infiltration.
Topics: Antibiotics, Antineoplastic; Bleomycin; Ear Neoplasms; Ear, External; Electrochemotherapy; Humans; K | 2010 |
Processing of procollagen III by meprins: new players in extracellular matrix assembly?
Topics: Bone Morphogenetic Protein 1; Cells, Cultured; Collagen Type III; Dermis; Extracellular Matrix Prote | 2010 |
Low-dose 5-fluorouracil induces cell cycle G2 arrest and apoptosis in keloid fibroblasts.
Topics: Adolescent; Adult; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Ch | 2010 |
Characterization of hyaluronan and TSG-6 in skin scarring: differential distribution in keloid scars, normal scars and unscarred skin.
Topics: Adolescent; Adult; Aged; Alpha-Globulins; Cell Adhesion Molecules; Cicatrix; Extracellular Matrix; F | 2011 |
[Surgical and radiotherapy in treatment of postauricular keloids--case report].
Topics: Ear, External; Humans; Keloid; Male; Postoperative Complications; Recurrence | 2010 |
Postoperative radiotherapy of auricular keloids: a 26-year experience.
Topics: Adult; Combined Modality Therapy; Ear Auricle; Female; Humans; Keloid; Male; Radiotherapy, Adjuvant; | 2011 |
Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: a case series.
Topics: Adult; Cicatrix; Cicatrix, Hypertrophic; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; P | 2010 |
[Spontaneous keloids: about a rare case].
Topics: Adult; Back; Female; Humans; Keloid; Prognosis; Rare Diseases; Thorax; Treatment Outcome | 2011 |
The tensile reduction effects of silicone gel sheeting.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Finite Element Analysis; Humans; Keloid; Materials | 2010 |
Phenotypic profiling of keloid scars using FT-IR microspectroscopy reveals a unique spectral signature.
Topics: Adult; Feasibility Studies; Female; Humans; Image Processing, Computer-Assisted; Keloid; Male; Middl | 2010 |
A novel in vitro assay for electrophysiological research on human skin fibroblasts: degenerate electrical waves downregulate collagen I expression in keloid fibroblasts.
Topics: Cells, Cultured; Collagen Type I; Down-Regulation; Electric Stimulation Therapy; Electrophysiologica | 2011 |
A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
Topics: Asian People; Case-Control Studies; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 15; Chromos | 2010 |
Keloid type of fibromatosis-like metaplastic carcinoma of the breast with transformation into biphasic tumour in recurrences and lymph node metastases.
Topics: Breast Neoplasms; Carcinoma; Female; Fibroma; Humans; Keloid; Keratin-5; Keratins; Lymphatic Metasta | 2010 |
Suppression of TGF-β1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid.
Topics: Adult; Aged; Cell Culture Techniques; Cells, Cultured; Chromatography, High Pressure Liquid; Curcumi | 2010 |
Surgical correction of severe Sprengel deformity to allow greater postoperative range of shoulder abduction.
Topics: Adolescent; Child; Child, Preschool; Cicatrix; Congenital Abnormalities; Female; Follow-Up Studies; | 2010 |
Intralesional injection of corticosteroids: a lesson from liposuction.
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Lipectom | 2010 |
The most current algorithms for the treatment and prevention of hypertrophic scars and keloids.
Topics: Algorithms; Cicatrix, Hypertrophic; Humans; Keloid | 2010 |
Modulation of metallothionein isoforms is associated with collagen deposition in proliferating keloid fibroblasts in vitro.
Topics: Cell Proliferation; Cells, Cultured; Collagen; Culture Media, Serum-Free; Down-Regulation; Fibroblas | 2010 |
Treatment of hypertrophic scars and keloids with a fractional CO2 laser: a personal experience.
Topics: Adult; Cicatrix, Hypertrophic; Female; Humans; Keloid; Lasers, Gas; Low-Level Light Therapy; Male; M | 2010 |
[Modified method of constructing tissue microarray which contains keloid and normal skin].
Topics: Adolescent; Adult; Female; Humans; Keloid; Male; Microarray Analysis; Middle Aged; Skin; Young Adult | 2010 |
Keloid explant culture: a model for keloid fibroblasts isolation and cultivation based on the biological differences of its specific regions.
Topics: Adolescent; Adult; Female; Fibroblasts; Humans; Keloid; Specimen Handling; Tissue Culture Techniques | 2010 |
The role of stem cell factor and c-KIT in keloid pathogenesis: do tyrosine kinase inhibitors have a potential therapeutic role?
Topics: Benzamides; Blotting, Western; Cell Communication; Cells, Cultured; Coculture Techniques; Fibroblast | 2011 |
Fibroblasts from the growing margin of keloid scars produce higher levels of collagen I and III compared with intralesional and extralesional sites: clinical implications for lesional site-directed therapy.
Topics: Adolescent; Adult; Biopsy; Blotting, Western; Collagen Type I; Collagen Type III; Female; Fibroblast | 2011 |
Experience of silicone gel sheets for patients with keloid scars after median sternotomy.
Topics: Administration, Topical; Adult; Aged; Female; Humans; Keloid; Male; Middle Aged; Silicone Gels; Ster | 2010 |
Effects of contractubex on the prevention of postoperative peritoneal adhesion.
Topics: Allantoin; Animals; Cicatrix; Drug Combinations; Female; Heparin; Humans; Keloid; Peritoneal Cavity; | 2010 |
Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option.
Topics: Adult; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Dipeptides; Endopeptidases; Female; Fibr | 2010 |
Cell talk: a phenomenon observed in the keloid scar by immunohistochemical study.
Topics: Antigens, CD; Cell Communication; Cicatrix; Collagen; Cytokines; Female; Fibroblasts; Humans; Immuno | 2011 |
Hyaluronic acid filler for steroid atrophy.
Topics: Atrophy; Cicatrix; Female; Humans; Hyaluronic Acid; Keloid; Middle Aged | 2010 |
TGF-ß1 antisense impacts the SMAD signalling system in fibroblasts from keloid scars.
Topics: DNA, Antisense; Fibroblasts; Humans; Immunohistochemistry; Keloid; Reverse Transcriptase Polymerase | 2010 |
[Construction of periostin shRNA vectors and their effects on the expression of periostin in fibroblasts].
Topics: Cell Adhesion Molecules; Cell Line; Fibroblasts; Genetic Vectors; Humans; Keloid; Lentivirus; Recomb | 2010 |
Prospective study of intraabdominal adhesions among women of different races with or without keloids.
Topics: Abdominal Cavity; Asian People; Black or African American; Female; Hispanic or Latino; Humans; Keloi | 2011 |
Xanthoma tuberosum; keloid; Jacquet posterosive syphiloid.
Topics: Humans; Keloid; Syphilis, Cutaneous; Tuberculosis, Cutaneous; Xanthomatosis | 1946 |
A case of generalized cholera treated by parathyroidectomy.
Topics: Humans; Keloid; Parathyroidectomy | 1946 |
Keloid formation in both ear lobes.
Topics: Ear Auricle; Keloid | 1946 |
Case of keloid.
Topics: Humans; Keloid | 1946 |
Multiple keloids following varicella.
Topics: Chickenpox; Humans; Keloid | 1946 |
Primitive Keloids of spontaneous remission.
Topics: Keloid | 1946 |
Pathophysiologic changes in a patient with early-onset extensive keloid disease and a 20-year follow-up.
Topics: Adult; Age of Onset; Follow-Up Studies; Humans; Keloid; Male; Recurrence | 2010 |
Intralesional cryosurgery for the treatment of hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Cryosurgery; Humans; Keloid | 2010 |
Adenovirus-mediated human interleukin 24 (MDA-7/IL-24) selectively suppresses proliferation and induces apoptosis in keloid fibroblasts.
Topics: Adenoviridae; Adolescent; Adult; Apoptosis; Cell Line; Cell Proliferation; Cell Survival; Cells, Cul | 2011 |
The cost effectiveness of intralesional steroid therapy for keloids.
Topics: Adolescent; Adult; Cost-Benefit Analysis; Ear, External; Face; Glucocorticoids; Head; Humans; Inject | 2010 |
Vitamin D: a novel therapeutic approach for keloid, an in vitro analysis.
Topics: Adolescent; Adult; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Collagen; | 2011 |
Suppression of keloid fibroblast.
Topics: Curcumin; Dermatitis, Contact; Extracellular Matrix; Fibroblasts; Humans; Keloid; Quercetin | 2011 |
Keloid histopathology after intralesional cryosurgery treatment.
Topics: Aged; Cryosurgery; Female; Humans; Keloid; Middle Aged | 2011 |
Analgesic benefit of niacin for shrapnel wound pain in war veteran.
Topics: Aged, 80 and over; Analgesia; Blast Injuries; Cicatrix, Hypertrophic; Humans; Hyperlipidemias; Hypol | 2010 |
Presentation and management of keloid scarring following median sternotomy: a case study.
Topics: Cardiac Surgical Procedures; Female; Heart Valve Diseases; Humans; Keloid; Middle Aged; Mitral Valve | 2010 |
Positive response of a recurrent keloid scar to topical methyl aminolevulinate-photodynamic therapy.
Topics: Adult; Aminolevulinic Acid; Female; Fibroblasts; Humans; Keloid; Photochemotherapy; Photosensitizing | 2010 |
The role of hepatocyte growth factor/c-Met system in keloid pathogenesis.
Topics: Analysis of Variance; Blotting, Western; Cells, Cultured; Fibroblasts; Hepatocyte Growth Factor; Hum | 2010 |
The role of R-spondin2 in keratinocyte proliferation and epidermal thickening in keloid scarring.
Topics: beta Catenin; Cell Proliferation; Cells, Cultured; Coculture Techniques; Epidermis; Fibroblasts; HEK | 2011 |
Molecular cloning, in vitro expression and bioactivity of rabbit transforming growth factor-beta receptor type II (rTGF-βRII).
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cloning, Molecular; Fibroblasts; In | 2011 |
[Significance of the secreted frizzled-related protein 2 expression in earlobe keloid].
Topics: Adolescent; Adult; Ear; Female; Humans; Keloid; Male; Membrane Proteins; Middle Aged; Young Adult | 2010 |
Vitamin E--an aid to wound healing?
Topics: Administration, Topical; Antioxidants; Female; Humans; Keloid; Male; Postoperative Care; Sensitivity | 2011 |
Crocodile tail-like giant keloid of the sacral region.
Topics: Alligators and Crocodiles; Animals; Humans; Keloid; Sacrococcygeal Region | 2011 |
Smad interacting protein 1 as a regulator of skin fibrosis in pathological scars.
Topics: Adolescent; Adult; Aged; Child; Cicatrix; Collagen; Collagen Type I; Down-Regulation; Female; Fibrob | 2011 |
Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts.
Topics: Adolescent; Adult; Anti-Infective Agents; Case-Control Studies; Cell Proliferation; Cell Survival; C | 2011 |
Intradermal tacrolimus prevent scar hypertrophy in a rabbit ear model: a clinical, histological and spectroscopical analysis.
Topics: Animals; Cicatrix, Hypertrophic; Dermoscopy; Disease Models, Animal; Ear, External; Female; Hypertro | 2011 |
In vitro effect of 470 nm LED (Light Emitting Diode) in keloid fibroblasts.
Topics: Adult; Cell Count; Cells, Cultured; Female; Fibroblasts; Humans; Keloid; Lasers, Semiconductor; Midd | 2011 |
Irritant contact dermatitis caused by Ranunculus kotschyi Boiss in 6 cases.
Topics: Adult; Aged; Allantoin; Anti-Bacterial Agents; Anti-Inflammatory Agents; Arthralgia; Betamethasone; | 2011 |
Application of multidetector-row computed tomography in propeller flap planning.
Topics: Adolescent; Adult; Burns; Contracture; Female; Foot Ulcer; Humans; Keloid; Male; Middle Aged; Plasti | 2011 |
A clinical characterization of familial keloid disease in unique African tribes reveals distinct keloid phenotypes.
Topics: Biomechanical Phenomena; Black People; Female; Humans; Keloid; Male; Phenotype; Sudan | 2011 |
Re: Valand K, McLoughlin PM. Encapsuloma: a case report.
Topics: Female; Granuloma, Foreign-Body; Humans; Joint Prosthesis; Keloid; Postoperative Complications; Temp | 2011 |
[Keloid development on skin lesions after the application of a cream purchased over the internet].
Topics: Administration, Cutaneous; Adult; Anacardium; Chelidonium; Dermatologic Agents; Humans; Internet; Ke | 2011 |
Modulatory effects of connexin-43 expression on gap junction intercellular communications with mast cells and fibroblasts.
Topics: Actins; Animals; Cell Culture Techniques; Connexin 43; Fibroblasts; Fibrosis; Gap Junctions; Gene Ex | 2011 |
Effect of selenocystine on gene expression profiles in human keloid fibroblasts.
Topics: Cells, Cultured; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Humans; Keloid; | 2011 |
Role of caveolin-1 in the pathogenesis of tissue fibrosis by keloid-derived fibroblasts in vitro.
Topics: Blotting, Western; Caveolin 1; Cell Survival; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fi | 2011 |
Association of HLA haplotype with keloids in Chinese Hans.
Topics: Adolescent; Adult; Aged; Asian People; Child; Child, Preschool; China; Female; Gene Frequency; Genet | 2011 |
Acupuncture for keloid scar.
Topics: Acupuncture Therapy; Adult; Colles' Fracture; Female; Humans; Keloid; Needles; Treatment Outcome; Wr | 2011 |
Trichostatin A inhibits collagen synthesis and induces apoptosis in keloid fibroblasts.
Topics: Adolescent; Adult; Apoptosis; Cell Proliferation; Cell Survival; Cells, Cultured; Child; Collagen; F | 2011 |
Keloids can be forced into remission with surgical excision and radiation, followed by adjuvant therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Chemotherapy, Adjuvant; Child; | 2011 |
Use of silicone gel sheets for prevention of keloid scars after median sternotomy.
Topics: Adolescent; Adult; Aged; Female; Humans; Keloid; Male; Middle Aged; Silicone Gels; Sternotomy; Treat | 2011 |
Study of microvascular structure in keloid and hypertrophic scars: density of microvessels and the efficacy of three-dimensional vascular imaging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Capillaries; Child; Cicatrix, Hypertrophic; Cohort Studi | 2010 |
Keloid formation after syndactyly release in patients with associated macrodactyly: management with methotrexate therapy.
Topics: Adolescent; Child; Child, Preschool; Compression Bandages; Dermatologic Agents; Drug Therapy, Combin | 2011 |
[Recommendations for the prevention and therapy of hypertrophic scars and keloids].
Topics: Cicatrix, Hypertrophic; Dermatology; Germany; Humans; Keloid | 2011 |
Images in clinical medicine. Keloidal morphea.
Topics: Adult; Diagnosis, Differential; Female; Humans; Keloid; Scleroderma, Localized; Skin | 2011 |
Management of chest keloids.
Topics: Adult; Combined Modality Therapy; Female; Humans; Injections, Intralesional; Keloid; Male; Steroids; | 2011 |
What's new in treatment of keloids? New applications for common therapies, new treatments to come.
Topics: Adjuvants, Immunologic; Aminoquinolines; Fluorouracil; Humans; Imiquimod; Immunosuppressive Agents; | 2011 |
Insights gained from the reverse engineering of gene networks in keloid fibroblasts.
Topics: Algorithms; Binding Sites; Culture Media, Serum-Free; Databases, Genetic; Fibroblasts; Gene Regulato | 2011 |
Eruptive keloids associated with breast cancer: a paraneoplastic phenomenon?
Topics: Breast Neoplasms, Male; Humans; Keloid; Male; Mastectomy; Paraneoplastic Syndromes; Pruritus; Skin; | 2011 |
Clinical applications of basic research that shows reducing skin tension could prevent and treat abnormal scarring: the importance of fascial/subcutaneous tensile reduction sutures and flap surgery for keloid and hypertrophic scar reconstruction.
Topics: Cicatrix, Hypertrophic; Clinical Trials as Topic; Dermatologic Surgical Procedures; Fascia; Humans; | 2011 |
Radiofrequency tissue volume reduction for treatment of auricle keloids.
Topics: Adolescent; Adult; Aged; Catheter Ablation; Child; Ear Auricle; Ear Diseases; Female; Humans; Keloid | 2011 |
Keloid skin scars: the influence of hyperbaric oxygenation on fibroblast growth and on the expression of messenger RNA for insulin like growth factor and for transforming growth factor.
Topics: Fibroblasts; Humans; Hyperbaric Oxygenation; Insulin-Like Growth Factor I; Keloid; RNA, Messenger; T | 2011 |
Cellular viability, collagen deposition, and transforming growth factor β1 production among ultraviolet B-irradiated keloid fibroblasts.
Topics: Cell Survival; Cells, Cultured; Collagen; Fibroblasts; Humans; Keloid; Transforming Growth Factor be | 2011 |
Automated classification of healthy and keloidal collagen patterns based on processing of SHG images of human skin.
Topics: Algorithms; Collagen; Electron Microscope Tomography; Electronic Data Processing; Humans; Image Proc | 2011 |
Adenovirus-relaxin gene therapy for keloids: implication for reversing pathological fibrosis.
Topics: Adenoviridae; Adult; Collagen Type I; Collagen Type III; Enzyme-Linked Immunosorbent Assay; Female; | 2011 |
Management of ear lobule keloids using 980-nm diode laser.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Combined Modality Therapy; Ear Diseases; Ear, External; | 2012 |
Multiphoton microscopy study of the morphological and quantity changes of collagen and elastic fiber components in keloid disease.
Topics: Adult; Cells, Cultured; Collagen; Elastic Tissue; Equipment Design; Equipment Failure Analysis; Fema | 2011 |
Fussel-15, a new player in wound healing, is deregulated in keloid and localized scleroderma.
Topics: Actins; Biological Assay; Cell Adhesion; Cell Line; Cell Movement; Cell Proliferation; Co-Repressor | 2011 |
Treatment of keloids and hypertrophic scars using topical and intralesional mitomycin C.
Topics: Administration, Topical; Adolescent; Adult; Aged; Cicatrix, Hypertrophic; Female; Humans; Injections | 2012 |
Transcriptional inhibition of hypertrophic scars by a gene silencer, pyrrole-imidazole polyamide, targeting the TGF-β1 promoter.
Topics: Animals; Cicatrix, Hypertrophic; Collagen Type I; Connective Tissue Growth Factor; DNA; Fibronectins | 2011 |
Conventional Epi-LASIK and lamellar epithelial debridement in myopic patients with dermatologic keloids.
Topics: Adult; Debridement; Eyeglasses; Female; Follow-Up Studies; Humans; Keloid; Keratomileusis, Laser In | 2011 |
Collagen triple helix repeat containing-1 inhibits transforming growth factor-b1-induced collagen type I expression in keloid.
Topics: Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen Type I; Extracellular Matrix Protei | 2011 |
Upregulation of Toll-like receptors (TLRs) 6, 7, and 8 in keloid scars.
Topics: DNA Primers; DNA, Viral; Gene Expression Regulation; Humans; Immune System; Keloid; Keratinocytes; P | 2011 |
miRNA expression profiles in keloid tissue and corresponding normal skin tissue.
Topics: Gene Expression Profiling; Humans; Keloid; MicroRNAs; Oligonucleotide Array Sequence Analysis; Skin | 2012 |
Plastic and reconstructive surgery in Zambia: epidemiology of 16 years of practice.
Topics: Adolescent; Adult; Age Distribution; Child; Child, Preschool; Congenital Abnormalities; Developing C | 2012 |
[Proteomic analysis between keloid and normal skin].
Topics: Adolescent; Adult; Female; Humans; Keloid; Male; Proteins; Proteome; Proteomics; Skin; Young Adult | 2011 |
Clinical characteristics of facial keloids treated with surgical excision followed by intra- and postoperative intralesional steroid injections.
Topics: Adult; Face; Female; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Male; Middle Aged; | 2012 |
Prevention and management of keloid scars.
Topics: Adult; Cesarean Section; Cesarean Section, Repeat; Combined Modality Therapy; Diagnosis, Differentia | 2011 |
Trauma injuries.
Topics: Air Bags; Atrophy; Burns; Cryotherapy; Glucocorticoids; Humans; Hyphema; Keloid; Skin; Warts; Wounds | 2011 |
[Identification of biological characteristics of human keloid-derived stem cells].
Topics: Adolescent; Cell Differentiation; Cell Proliferation; Cells, Cultured; Child; Coculture Techniques; | 2011 |
Cosmetic procedures in skin of color.
Topics: Chemexfoliation; Cosmetic Techniques; Culture; Esthetics; Hair Removal; Hirsutism; Humans; Keloid; L | 2011 |
Spontaneous resolution of a keloid.
Topics: Adult; Diagnosis, Differential; Follow-Up Studies; Humans; Keloid; Male; Remission, Spontaneous; Tho | 2011 |
Outcomes of surgical excision with pressure therapy using magnets and identification of risk factors for recurrent keloids.
Topics: Adult; Bandages; Ear Diseases; Ear, External; Equipment Design; Female; Follow-Up Studies; Humans; K | 2011 |
Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression.
Topics: Adolescent; Adult; Angiotensin II; Cell Movement; Cell Proliferation; Dermis; Disease Progression; F | 2011 |
Mechanobiology of scarring.
Topics: Animals; Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Mechanoreceptors; Models, Animal; Skin; S | 2011 |
Assessment of the influence of HLA class I and class II loci on the prevalence of keloid disease in Jamaican Afro-Caribbeans.
Topics: Adult; Alleles; Black People; Ethnicity; Female; Genetic Predisposition to Disease; Histocompatibili | 2011 |
Extracellular matrix molecules implicated in hypertrophic and keloid scarring.
Topics: Cicatrix, Hypertrophic; Extracellular Matrix; Extracellular Matrix Proteins; Glycosaminoglycans; Hum | 2012 |
Effects of hepatocyte growth factor on collagen synthesis and matrix metalloproteinase production in keloids.
Topics: Cells, Cultured; Collagen Type I; Collagen Type III; Fibroblasts; Hepatocyte Growth Factor; Humans; | 2011 |
Scars.
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid; Laser Therapy; Striae Distensae | 2011 |
Identification and characterization of cartilage oligomeric matrix protein as a novel pathogenic factor in keloids.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cartilage Oligomeric Matrix Protein; Child; Child, Presc | 2011 |
Radiotherapy treatment of keloid scars with a kilovoltage X-ray parallel pair.
Topics: Adolescent; Adult; Aged; Female; Humans; Keloid; Male; Middle Aged; X-Rays | 2012 |
An unusual complication of foetal blood sampling.
Topics: Blood Specimen Collection; Child, Preschool; Female; Humans; Keloid; Male; Perinatal Care; Pregnancy | 2011 |
Vaccine-associated fibrosarcoma with keloidal differentiation in a cat.
Topics: Animals; Cat Diseases; Cats; Female; Fibrosarcoma; Keloid; Leukemia Virus, Feline; Viral Vaccines | 2011 |
Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts.
Topics: Animals; Bees; Biological Factors; Cell Proliferation; Cells, Cultured; Fibroblasts; Honey; Humans; | 2011 |
Chronic osteomyelitis in the lower extremity predisposing to the unusual formation of keloids.
Topics: Ankle; Child; Chronic Disease; Fibula; Humans; Inflammation; Keloid; Lower Extremity; Male; Nigeria; | 2011 |
Compound Astragalus and Salvia miltiorrhiza extract inhibits cell proliferation, invasion and collagen synthesis in keloid fibroblasts by mediating transforming growth factor-β / Smad pathway.
Topics: Adult; Animals; Cattle; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Drugs, Chine | 2012 |
Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
Topics: Animals; beta Catenin; Cell Communication; Cell Movement; Cell Proliferation; Collagen; Collagen Typ | 2011 |
Hypoxia regulates the expression of extracellular matrix associated proteins in equine dermal fibroblasts via HIF1.
Topics: Animals; Apoptosis; Cell Proliferation; Cell Survival; Extracellular Matrix; Fibroblasts; Horses; Hu | 2012 |
Keloid fibroblasts are more sensitive to Wnt3a treatment in terms of elevated cellular growth and fibronectin expression.
Topics: Adolescent; Adult; beta Catenin; Blotting, Western; Case-Control Studies; Cell Movement; Cell Prolif | 2011 |
Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy.
Topics: Adult; Aged; Aminolevulinic Acid; Apoptosis; Blotting, Western; Case-Control Studies; Caspase 3; Cel | 2011 |
Factors associated with postpiercing auricular cartilage keloids.
Topics: Adolescent; Age Factors; Body Piercing; Child; Ear Cartilage; Humans; Keloid; Risk Factors; Wound He | 2011 |
Comparative genomic hybridisation analysis of keloid tissue in Caucasians suggests possible involvement of HLA-DRB5 in disease pathogenesis.
Topics: Adolescent; Adult; Aged; Child; Cicatrix; Cohort Studies; Comparative Genomic Hybridization; DNA Cop | 2012 |
Pirfenidone suppresses keloid fibroblast-embedded collagen gel contraction.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Collagen Type I; Connective Tissue | 2012 |
Interleukin-18 system plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions.
Topics: Caspase 1; Caspase 3; Cells, Cultured; Collagen; Enzyme Inhibitors; Epithelial-Mesenchymal Transitio | 2012 |
Long-term follow-up after lamellar keratoplasty in a patient with bilateral idiopathic corneal keloid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Corneal Diseases; Corneal Transplantation | 2011 |
Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy.
Topics: Adult; Aged; Ammonia; Cognitive Dysfunction; Fatty Liver; Female; Hepatic Encephalopathy; Humans; Hy | 2012 |
Earlobe keloids: classification according to gross morphology determines proper surgical approach.
Topics: Ear, External; Female; Humans; Keloid; Male; Punctures; Retrospective Studies; Surgical Flaps; Treat | 2012 |
Is photodynamic therapy a solution for keloid?
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Photochemotherapy | 2011 |
[Establishment of molecular beacon real-time PCR for detecting p53 gene single nucleotide polymorphism].
Topics: Base Sequence; Codon; Humans; Keloid; Molecular Sequence Data; Polymorphism, Single Nucleotide; Real | 2011 |
Wound healing in adult skin: aiming for perfect regeneration.
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Female; Humans; Keloid; Male; Regeneration; Signal Transdu | 2011 |
Analyses of CDC2L1 gene mutations in keloid tissue.
Topics: Adolescent; Adult; Child; Chromatography, High Pressure Liquid; Cyclin-Dependent Kinases; DNA Mutati | 2012 |
[Ultrasonic dissection in operative treatment of scars].
Topics: Adult; Blood Loss, Surgical; Cicatrix, Hypertrophic; Dermatologic Surgical Procedures; Dissection; F | 2011 |
Histone deacetylase 2 is upregulated in normal and keloid scars.
Topics: Animals; Cells, Cultured; Cicatrix; Fibroblasts; Histone Deacetylase 2; Humans; Keloid; Male; Mice; | 2012 |
[Experimental study on protein expression of extracellular signal-regulated kinase and c-Jun amino-terminal kinase signaling pathways in keloid fibroblasts].
Topics: Adolescent; Adult; Child; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Humans; I | 2011 |
Involvement of upper torso stress amplification, tissue compression and distortion in the pathogenesis of keloids.
Topics: Biomechanical Phenomena; Collagen; Elastic Modulus; Eyelids; Humans; Keloid; Skin; Stress, Mechanica | 2012 |
Quantification of the physical properties of keloid and hypertrophic scars using the Vesmeter novel sensing device.
Topics: Cicatrix; Elasticity; Follow-Up Studies; Hardness; Humans; Hypertrophy; Keloid; Viscosity | 2012 |
Proteoglycans of uterine fibroids and keloid scars: similarity in their proteoglycan composition.
Topics: Adolescent; Adult; Extracellular Matrix; Female; Humans; Keloid; Leiomyoma; Middle Aged; Proteoglyca | 2012 |
A technique for auricular keloid core excision using a skin biopsy punch.
Topics: Adolescent; Adult; Biopsy; Ear Auricle; Ear Diseases; Female; Humans; Keloid; Plastic Surgery Proced | 2012 |
A new uniform protocol of combined corticosteroid injections and ointment application reduces recurrence rates after surgical keloid/hypertrophic scar excision.
Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Drug Therapy, Combi | 2012 |
Effect of heat shock protein 47 on collagen synthesis of keloid in vivo.
Topics: Adolescent; Adult; Animals; Blotting, Western; Collagen; Disease Models, Animal; Female; Fibroblasts | 2011 |
Effects of the cyclin-dependent kinase 10 (CDK10) on the tamoxifen sensitivity of keloid samples.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Cyclin-Dependent Kinases; Flow Cytometry; Huma | 2012 |
Ginseng as a potential novel addition to the antikeloid weaponry.
Topics: Acetylcholinesterase; Animals; Ginsenosides; Humans; Interleukin-6; Keloid; Matrix Metalloproteinase | 2012 |
[Study of TGF-β1 phage model peptides on inhibiting keloid fibroblasts proliferation].
Topics: Apoptosis; Cell Proliferation; Cells, Cultured; Connective Tissue Growth Factor; Fibroblasts; Humans | 2011 |
[Clinical efficacy of keloids treated by surgical ablation and immediate postoperative adjuvant radiotherapy].
Topics: Adult; Female; Humans; Keloid; Male; Radiotherapy Dosage | 2011 |
Keloids: what do we know and what do we do next?
Topics: Angiogenesis Inhibitors; Animals; Endostatins; Female; Humans; Keloid; Male; Neovascularization, Pat | 2012 |
Altered angiogenic balance in keloids: a key to therapeutic intervention.
Topics: Adolescent; Adult; Aged; Angiogenesis Inhibitors; Animals; Case-Control Studies; Child; Collagen Typ | 2012 |
miR-196a downregulation increases the expression of type I and III collagens in keloid fibroblasts.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Collagen Type I; Collagen Type III; CpG Islands; Dermis; | 2012 |
Madecassoside suppresses migration of fibroblasts from keloids: involvement of p38 kinase and PI3K signaling pathways.
Topics: Actin Cytoskeleton; Analysis of Variance; Cell Movement; Cells, Cultured; Cofilin 1; Fibroblasts; Hu | 2012 |
Treatment outcomes for keloid scar management in the pediatric burn population.
Topics: Adolescent; Adult; Burns; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Infant | 2012 |
Patient-related keloid scar assessment and outcome measures.
Topics: Adolescent; Adult; Humans; Keloid; Middle Aged; Observer Variation; Outcome Assessment, Health Care; | 2012 |
Cutaneous innervation and itch in keloids.
Topics: Adolescent; Adult; Biomarkers; Biopsy; Case-Control Studies; Female; Humans; Keloid; Male; Microscop | 2012 |
Nodular/keloidal scleroderma: acquired collagenous nodules in systemic sclerosis.
Topics: Aged; Collagen; Disease Progression; Female; Humans; Keloid; Middle Aged; Scleroderma, Diffuse; Scle | 2012 |
Laser CO2 versus radiotherapy in treatment of keloid scars.
Topics: Adolescent; Adult; Combined Modality Therapy; Female; Humans; Keloid; Lasers, Gas; Male; Young Adult | 2012 |
Commentary: earlobe keloids: classification by gross morphology determines proper surgical approach.
Topics: Ear, External; Female; Humans; Keloid; Male | 2012 |
Evaluating keloid recurrence after surgical excision with prospective longitudinal scar assessment scales.
Topics: Adult; Female; Humans; Keloid; Male; Outcome Assessment, Health Care; Patient Satisfaction; Prospect | 2012 |
[Spontaneous keloid on the breast].
Topics: Aged, 80 and over; Biopsy; Breast; Breast Diseases; Diagnosis, Differential; Female; Humans; Keloid; | 2012 |
Psychological stress as a risk factor for postoperative keloid recurrence.
Topics: Adult; Anxiety Disorders; Arousal; Depressive Disorder; Female; Follow-Up Studies; Galvanic Skin Res | 2012 |
Protein profiling of keloidal scar tissue.
Topics: Adult; Aged; Cell Extracts; Chromatography, Liquid; Female; Humans; Keloid; Keratins, Type II; Male; | 2012 |
Identification of fibrocytes from mesenchymal stem cells in keloid tissue: a potential source of abnormal fibroblasts in keloid scarring.
Topics: Adult; Aged; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cicatrix; | 2012 |
Infrequent p53 gene mutation but UV gradient-like p53 protein positivity in keloids.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Gene Expression; Gene Frequency; Genes, p53; Hum | 2012 |
Oxymatrine inhibits collagen synthesis in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway.
Topics: Adult; Alkaloids; Analysis of Variance; Antiviral Agents; Cell Proliferation; Cells, Cultured; Colla | 2012 |
Giant keloid of left buttock treated with post-excisional radiotherapy.
Topics: Buttocks; Humans; Keloid; Male; Radiotherapy, Adjuvant; Secondary Prevention; Young Adult | 2011 |
Letter regarding "management of ear lobule keloids using 980-nm diode laser".
Topics: Ear Diseases; Ear, External; Female; Humans; Keloid; Lasers, Semiconductor; Low-Level Light Therapy; | 2012 |
FK506 inhibits the enhancing effects of transforming growth factor (TGF)-β1 on collagen expression and TGF-β/Smad signalling in keloid fibroblasts: implication for new therapeutic approach.
Topics: Adult; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Down-Regulation; Female; Fibrob | 2012 |
[Keloid scars on black skin: myth or reality].
Topics: Adolescent; Adult; Black People; Child; Child, Preschool; Cicatrix; Cote d'Ivoire; Female; Glucocort | 2013 |
A new carbon dioxide laser combined with cyanoacrylate glue to treat earlobe keloids.
Topics: Bandages; Ear Diseases; Ear, External; Female; Humans; Keloid; Magnetic Field Therapy; Male; Pressur | 2012 |
X-linked recessive polyfibromatosis manifesting with spontaneous keloid scars and Dupuytren's contracture.
Topics: Adolescent; Adult; Dupuytren Contracture; Female; Fibroma; Genetic Diseases, X-Linked; Humans; Keloi | 2012 |
A novel approach for management of ear keloids: results of excision combined with 5-fluorouracil injection.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Antimetabolites; Chi-Square Distribution; Combined Moda | 2012 |
Collapsing angiokeloidal dermatofibroma.
Topics: Adult; Biomarkers, Tumor; Biopsy; Blood Vessels; Buttocks; Female; Histiocytoma, Benign Fibrous; Hum | 2012 |
Nodular scleroderma presenting as multiple spontaneous keloidal scars.
Topics: Adolescent; Cicatrix, Hypertrophic; Female; Humans; Keloid; Scleroderma, Systemic | 2012 |
Highlights of thirty-year experience of CO2 laser use at the Florence (Italy) department of dermatology.
Topics: Cicatrix, Hypertrophic; Dermatologic Surgical Procedures; Dermatology; Female; Humans; Italy; Keloid | 2012 |
Enhanced expression of membrane transporter and drug resistance in keloid fibroblasts.
Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; | 2012 |
Deep and superficial keloid fibroblasts contribute differentially to tissue phenotype in a novel in vivo model of keloid scar.
Topics: Adolescent; Animals; Cells, Cultured; Child; Collagen Type I; Collagen Type I, alpha 1 Chain; Diseas | 2012 |
Letter regarding "Treatment outcomes for keloid scar management in the pediatric burn population".
Topics: Burns; Female; Humans; Keloid; Male; Steroids | 2012 |
Characterization of oral ulcer and pathological scar in nude mice model.
Topics: Animals; Cicatrix; Disease Models, Animal; Fibrosis; Humans; Hydrochloric Acid; Immunohistochemistry | 2012 |
"X"-shaped incision and keloid skin-flap resurfacing: a new surgical method for auricle keloid excision and reconstruction.
Topics: Ear Auricle; Humans; Keloid; Plastic Surgery Procedures; Surgical Flaps | 2012 |
Nanosilver as a novel agent in keloid therapy.
Topics: Humans; Keloid; Metal Nanoparticles; Micelles; Silver | 2013 |
[Establishment of a keloid model by transplanting human keloid onto the backs of nude mice].
Topics: Animals; Disease Models, Animal; Female; Humans; Keloid; Mice; Mice, Nude; Transplantation, Heterolo | 2014 |
Keloidal dermatofibroma: report of a rare dermatofibroma variant in a young white woman.
Topics: Adolescent; Biomarkers, Tumor; Biopsy; Female; Histiocytoma, Benign Fibrous; Humans; Immunohistochem | 2013 |
Cellular delivery of cationic lipid nanoparticle-based SMAD3 antisense oligonucleotides for the inhibition of collagen production in keloid fibroblasts.
Topics: Cells, Cultured; Collagen Type I; Drug Stability; Drug Storage; Fibroblasts; Fibrosis; Humans; Keloi | 2012 |
Can single use negative pressure wound therapy be an alternative method to manage keloid scarring? A preliminary report of a clinical and ultrasound/colour-power-doppler study.
Topics: Adolescent; Adult; Child; Compression Bandages; Female; Follow-Up Studies; Humans; Keloid; Male; Neg | 2013 |
[Combination therapy of earlobe keloids by surgery].
Topics: Adolescent; Adult; Ear Auricle; Ear Diseases; Female; Humans; Keloid; Middle Aged; Young Adult | 2012 |
TGF-beta1 increases cell rigidity by enhancing expression of smooth muscle actin: keloid-derived fibroblasts as a model for cellular mechanics.
Topics: Actins; Adult; Case-Control Studies; Female; Fibroblasts; Gene Expression Regulation; Humans; Keloid | 2012 |
Association of TGFβ1 and SMAD4 variants in the etiology of keloid scar in the Malay population.
Topics: Adolescent; Adult; Case-Control Studies; Child; Female; Gene Frequency; Genetic Association Studies; | 2012 |
Atypical presentation of mucoepidermoid carcinoma after radiation therapy for the treatment of keloids.
Topics: Adult; Carcinoma, Mucoepidermoid; Female; Humans; Keloid; Parotid Gland; Parotid Neoplasms; Radiatio | 2012 |
Use of lipofilling for the treatment of severe burn outcomes.
Topics: Burns; Cicatrix, Hypertrophic; Follow-Up Studies; Humans; Keloid; Lipectomy; Patient Satisfaction; P | 2012 |
Differential cytotoxic response in keloid fibroblasts exposed to photodynamic therapy is dependent on photosensitiser precursor, fluence and location of fibroblasts within the lesion.
Topics: Adult; Aminolevulinic Acid; Apoptosis; Cell Differentiation; Cells, Cultured; Cellular Senescence; F | 2012 |
Keloid recurrence in pregnancy.
Topics: Adult; Female; Humans; Keloid; Pregnancy; Pregnancy Complications; Recurrence; Risk Factors; Young A | 2012 |
Keloid formation after circumcision and its treatment.
Topics: Administration, Topical; Child, Preschool; Circumcision, Male; Combined Modality Therapy; Humans; In | 2013 |
Clinical and histologic effects from CO2 laser treatment of keloids.
Topics: Adolescent; Adult; Female; Humans; Keloid; Lasers, Gas; Male; Middle Aged; Time Factors; Treatment O | 2013 |
Relaxin-expressing adenovirus decreases collagen synthesis and up-regulates matrix metalloproteinase expression in keloid fibroblasts: in vitro experiments.
Topics: Adenoviridae; Cell Line; Cells, Cultured; Collagen; Dermis; Extracellular Matrix; Fibroblasts; Human | 2012 |
German S2k guidelines for the therapy of pathological scars (hypertrophic scars and keloids).
Topics: Adrenal Cortex Hormones; Cicatrix, Hypertrophic; Cryotherapy; Dermatologic Surgical Procedures; Derm | 2012 |
Botulinum toxin A for the treatment of keloids.
Topics: Actins; Botulinum Toxins, Type A; Cell Proliferation; Collagen; Female; Fibroblasts; Fibronectins; H | 2012 |
An ex vivo model employing keloid-derived cell-seeded collagen sponges for therapy development.
Topics: Adult; Animals; Chondroitin ABC Lyase; Disease Models, Animal; Extracellular Matrix; Female; Fibrobl | 2013 |
Ethnic disparity in skin complications following bone-anchored hearing aid implantation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone Conduction; Cicatrix, Hypertrophic; Cochlear Implan | 2012 |
Use of Integra and interval brachytherapy in a 2-stage auricular reconstruction after excision of a recurrent keloid.
Topics: Brachytherapy; Ear, External; Female; Humans; Keloid; Radiotherapy Dosage; Recurrence; Skin Transpla | 2012 |
[Palmar and plantar keloid in a black African male].
Topics: Adult; Cote d'Ivoire; Foot Dermatoses; Hand Dermatoses; Humans; Keloid; Male; Surgical Flaps; Syndac | 2012 |
The effect of TLR4/7 on the TGF-β-induced Smad signal transduction pathway in human keloid.
Topics: Adolescent; Adult; Blotting, Western; Collagen; Connective Tissue Growth Factor; Female; Humans; Imm | 2013 |
Letter regarding "Keloid formation after circumcision and its treatment".
Topics: Circumcision, Male; Humans; Keloid; Male; Penis; Steroids | 2013 |
Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor.
Topics: Adolescent; Adult; Aged; Animals; Apoptosis; Benzopyrans; Cell Adhesion; Cell Cycle; Cell Movement; | 2012 |
Letter regarding "Clinical and histologic effects from CO2 laser treatment of keloids".
Topics: Humans; Keloid; Lasers, Gas | 2012 |
Suggestion of end points of complete keloid excision.
Topics: Ear Auricle; Ear Diseases; Female; Humans; Keloid; Plastic Surgery Procedures | 2012 |
[Emerging strategies for the prevention and therapy of excessive scars].
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Aminoquinolines; Botulinum Toxins, Type A; Cicatrix | 2012 |
Numerical analysis of keloid scar in the presternal area.
Topics: Humans; Keloid; Likelihood Functions; Sternum; Stress, Mechanical | 2012 |
Current concepts in the etiology and treatment of keloids.
Topics: Adolescent; Adult; Child; Cicatrix, Hypertrophic; Clinical Protocols; Dermatologic Surgical Procedur | 2012 |
Utilizing topical therapies and mitomycin to reduce scars.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Child; Cicatrix, Hypertrophic; Dermatologic Surgical | 2012 |
Treatment of keloid formation following syndactyly division: surgical technique.
Topics: Adolescent; Child, Preschool; Female; Humans; Infant; Keloid; Male; Plastic Surgery Procedures; Post | 2012 |
Keloid scars and treatment with Botulinum Toxin Type A: the Belfast experience.
Topics: Adolescent; Adult; Botulinum Toxins, Type A; Child; Cohort Studies; Dose-Response Relationship, Drug | 2013 |
Increased KGF expression promotes fibroblast activation in a double paracrine manner resulting in cutaneous fibrosis.
Topics: Cell Communication; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblast | 2013 |
Site-specific immunophenotyping of keloid disease demonstrates immune upregulation and the presence of lymphoid aggregates.
Topics: Biomarkers; Biopsy; Case-Control Studies; Fluorescent Antibody Technique; Humans; Immunophenotyping; | 2012 |
Photodynamic therapy: an innovative approach to the treatment of keloid disease evaluated using subjective and objective non-invasive tools.
Topics: Aminolevulinic Acid; Collagen; Female; Hemoglobins; Humans; Keloid; Male; Melanins; Pain Measurement | 2013 |
Tryptase-positive mast cells and angiogenesis in keloids: a new possible post-surgical target for prevention.
Topics: Adult; Female; Humans; Keloid; Male; Mast Cells; Middle Aged; Neovascularization, Pathologic; Trypta | 2013 |
Auricular keloid burn.
Topics: Burns; Ear, External; Female; Humans; Keloid; Middle Aged; Remission, Spontaneous; Watchful Waiting | 2013 |
Are auricular keloids and persistent hypertrophic scars resectable? The role of intrascar excision.
Topics: Adolescent; Adult; Body Piercing; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Ear, Exter | 2012 |
Analysis of 15 cases of auricular keloids following conchal cartilage grafts in an asian population.
Topics: Adult; Asian People; Ear Auricle; Ear Cartilage; Female; Humans; Keloid; Male; Retrospective Studies | 2013 |
[Effects of oxymatrine on the expressions of pro-collagen and fibronectin of fibroblasts derived from human hyperplastic scars].
Topics: Alkaloids; Cells, Cultured; Cicatrix; Extracellular Matrix; Fibroblasts; Fibronectins; Humans; Keloi | 2012 |
Spontaneous keloid formation in patients with Bethlem myopathy.
Topics: Adult; Contracture; Female; Humans; Keloid; Male; Middle Aged; Muscular Dystrophies | 2012 |
[Efficacy of CO2 laser combined with 32P-patch contact brachyradiotherapy for the treatment of keloids].
Topics: Adolescent; Adult; Female; Humans; Keloid; Lasers, Gas; Male; Middle Aged; Phosphates; Phosphorus Ra | 2012 |
Are keloid and hypertrophic scar different forms of the same disorder? A fibroproliferative skin disorder hypothesis based on keloid findings.
Topics: Adult; Cicatrix, Hypertrophic; Collagen; Diagnosis, Differential; Female; Fibrillar Collagens; Fibro | 2014 |
Keloid pathogenesis via Drosophila similar to mothers against decapentaplegic (SMAD) signaling in a primary epithelial-mesenchymal in vitro model treated with biomedical-grade chitosan porous skin regenerating template.
Topics: Biocompatible Materials; Cells, Cultured; Chitosan; Coculture Techniques; Collagen Type I; Collagen | 2013 |
Keloid formation after trigger finger release: a case report.
Topics: Bandages; Humans; Keloid; Male; Middle Aged; Postoperative Complications; Skin Transplantation; Trig | 2013 |
[Gingira medicasol removes and prevents scars and keloids].
Topics: Centella; Cicatrix; Emulsions; Fibroblasts; Humans; Keloid; Plant Extracts; Wound Healing | 2012 |
Keloid scars in type VI skin successfully treated with combined surgery and pulsed dye laser therapy.
Topics: Adult; Combined Modality Therapy; Dermatologic Surgical Procedures; Humans; Keloid; Lasers, Dye; Mal | 2013 |
[Expression and significance of mRNA and protein of eIF4E, p-eIF4E and MCl-1 in pathological scar].
Topics: Adolescent; Adult; Case-Control Studies; Cicatrix; Eukaryotic Initiation Factor-4E; Female; Humans; | 2012 |
Extract of Aneilema keisak inhibits transforming growth factor-β-dependent signalling by inducing Smad2 downregulation in keloid fibroblasts.
Topics: Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Commelinaceae; Down-Regulation; Fibrob | 2013 |
Recurrence of large subcutaneous keloids after tissue expansion: two case reports.
Topics: Adult; Burns; Esthetics; Female; Follow-Up Studies; Humans; Injury Severity Score; Keloid; Neck; Pla | 2013 |
Potent dual inhibitors of TORC1 and TORC2 complexes (KU-0063794 and KU-0068650) demonstrate in vitro and ex vivo anti-keloid scar activity.
Topics: Adolescent; Adult; Aged; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relations | 2013 |
Cutaneous cryosurgery.
Topics: Condylomata Acuminata; Cryosurgery; Histiocytoma, Benign Fibrous; Humans; Keloid; Keratosis, Actinic | 2012 |
JAAD Grand Rounds quiz. Keloidal nodules in an African American man.
Topics: Aged; Black or African American; Diagnosis, Differential; Histiocytosis, Sinus; Humans; Keloid; Male | 2013 |
[Adjuvant treatment of keloid scars: electrons or brachytherapy?].
Topics: Adolescent; Adult; Aged; Brachytherapy; Child; Dose-Response Relationship, Radiation; Electrons; Fem | 2013 |
Up-regulation of tension-related proteins in keloids: knockdown of Hsp27, α2β1-integrin, and PAI-2 shows convincing reduction of extracellular matrix production.
Topics: Adolescent; Adult; Aged; Extracellular Matrix; Female; Fibroblasts; HSP27 Heat-Shock Proteins; Human | 2013 |
Early postoperative magnet application combined with hydrocolloid dressing for the treatment of earlobe keloids.
Topics: Adolescent; Adult; Bandages, Hydrocolloid; Case-Control Studies; Combined Modality Therapy; Ear, Ext | 2013 |
Combined treatment of earlobe keloids with shaving, cryosurgery, and intralesional steroid injection: a 1-year follow-up.
Topics: Adolescent; Adult; Cell Proliferation; Combined Modality Therapy; Cryosurgery; Curettage; Ear Diseas | 2013 |
[Keloids and hypertension in black subjects: a case-control study].
Topics: Adolescent; Adult; Black People; Case-Control Studies; Disease Susceptibility; Female; Humans; Hyper | 2013 |
Radiotherapy in the management of keloids. Clinical experience with electron beam irradiation and comparison with X-ray therapy.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Electrons; Female; Follow-Up Studies; Humans; Kelo | 2002 |
Surgical pearl: excision with suprakeloidal flap and radiation therapy for keloids.
Topics: Adult; Ear, External; Female; Humans; Keloid; Postoperative Period | 2002 |
Genetic susceptibility to keloid disease and transforming growth factor beta 2 polymorphisms.
Topics: Cicatrix, Hypertrophic; Genetic Predisposition to Disease; Genotype; Humans; Keloid; Polymorphism, G | 2002 |
Triamcinolone stimulates bFGF production and inhibits TGF-beta1 production by human dermal fibroblasts.
Topics: Analysis of Variance; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2 | 2002 |
[Detection of apoptosis by in situ labeling and study on the expression of PCNA in hypertrophic scars and keloids].
Topics: Adolescent; Adult; Apoptosis; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Histoc | 2000 |
Lymphangioma circumscriptum of the vulva following surgical and radiological therapy of cervical cancer.
Topics: Aged; Carbon Dioxide; Combined Modality Therapy; Female; Humans; Keloid; Laser Therapy; Lymphangioma | 2002 |
Pilot study of the effect of postoperative imiquimod 5% cream on the recurrence rate of excised keloids.
Topics: Adjuvants, Immunologic; Administration, Topical; Adult; Aminoquinolines; Ear, External; Female; Foll | 2002 |
The effect of carboxymethyl-chitosan on proliferation and collagen secretion of normal and keloid skin fibroblasts.
Topics: Adult; Biocompatible Materials; Cell Division; Cells, Cultured; Chitin; Chitosan; Collagen; Electrop | 2002 |
Fibrodysplasia ossificans progressiva and corneal keloid.
Topics: Child; Corneal Diseases; Humans; Keloid; Male; Myositis Ossificans; Ophthalmologic Surgical Procedur | 2002 |
[Detection and analysis of Fas gene (exon 1-6) mutations in keloids].
Topics: Adult; DNA; Exons; fas Receptor; Female; Humans; Keloid; Male; Mutation; Polymerase Chain Reaction; | 2002 |
Health disparities in arthritis and musculoskeletal and skin diseases-the dermatology session: National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, Maryland, December 15-16, 2000.
Topics: Acne Vulgaris; Black People; Health Surveys; Humans; Keloid; Minority Groups; Racial Groups; Researc | 2002 |
[Etiology of keloids in Kinshasa, Democratic Republic of Congo: a retrospective study on 768 patients].
Topics: Adult; Age Factors; Aged; Democratic Republic of the Congo; Female; Humans; Incidence; Keloid; Male; | 2002 |
Phenotypic differences between dermal fibroblasts from different body sites determine their responses to tension and TGFbeta1.
Topics: Actins; Apoptosis; Biopsy; Cells, Cultured; Collagen Type I; Dermis; Fibroblasts; Fibronectins; Huma | 2002 |
Painless steroid injections for hypertrophic scars and keloids.
Topics: Anesthesia, Local; Anesthetics, Local; Bupivacaine; Cicatrix, Hypertrophic; Humans; Injections, Intr | 2002 |
[A study of interaction between keratinocytes and fibroblasts in keloid].
Topics: Adolescent; Adult; Apoptosis; Blotting, Western; Cell Communication; Cell Division; Cells, Cultured; | 2002 |
Use of keloid cutis as reconstructive flap of the auricle after keloid excision.
Topics: Adolescent; Ear, External; Female; Humans; Keloid; Punctures; Surgical Flaps | 2003 |
[Overexpression of truncated type II transforming growth factor-beta receptor in dermal fibroblasts].
Topics: Cell Division; Cells, Cultured; Fibroblasts; Gene Expression; Genetic Therapy; Humans; Keloid; Prote | 2002 |
[Expression of platelet derived growth factor receptor-beta in fibroblasts of keloid].
Topics: Cells, Cultured; Fibroblasts; Flow Cytometry; Humans; Keloid; Microscopy, Confocal; Receptor, Platel | 2000 |
[The experimental study of intracellular actin in the scar fibroblasts].
Topics: Actins; Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; | 2000 |
Giant right plantar keloid treated with excision and tissue-engineered allograft.
Topics: Adult; Foot Dermatoses; Humans; Keloid; Male; Skin Transplantation; Tissue Engineering; Transplantat | 2003 |
[Radiotherapy of keloids. Patterns of care study -- results].
Topics: Critical Pathways; Dose Fractionation, Radiation; Electrons; Follow-Up Studies; Germany; Humans; Kel | 2003 |
Effect of mitomycin C on keloid fibroblasts: an in vitro study.
Topics: Cell Division; Cell Line; Cell Survival; Cells, Cultured; Cross-Linking Reagents; DNA; Fibroblasts; | 2003 |
Genetic susceptibility to keloid disease and hypertrophic scarring: transforming growth factor beta1 common polymorphisms and plasma levels.
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Codon; Female; Gene Frequency; Genetic Predisposition to | 2003 |
Postoperative electron-beam irradiation therapy for keloids and hypertrophic scars: retrospective study of 147 cases followed for more than 18 months.
Topics: Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Electrons; Female; Humans; Keloid; Male; M | 2003 |
The small-wave incision for long keloids.
Topics: Abdominal Wall; Adult; Female; Humans; Keloid; Suture Techniques; Tissue Adhesives | 2003 |
[Experimental study of actin and myosin in the scar tissue].
Topics: Actins; Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; | 2001 |
[Prevention of keloids of the earlobes].
Topics: Adolescent; Adult; Aged; Dermatitis, Allergic Contact; Ear, External; Female; Gold Compounds; Humans | 1999 |
[The mast cell and trauma].
Topics: Burns; Forensic Medicine; Fractures, Bone; Humans; Inflammation; Keloid; Mast Cells; Wound Healing; | 2002 |
Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.
Topics: Animals; Antibodies, Monoclonal; Base Sequence; Breast; Cell Division; DNA Primers; Epidermal Cells; | 2003 |
Role of IGF system of mitogens in the induction of fibroblast proliferation by keloid-derived keratinocytes in vitro.
Topics: Antibodies; Cell Division; Cell Line; Coculture Techniques; Fibroblasts; Humans; Insulin-Like Growth | 2003 |
Gene transfer into human keloid tissue with adeno-associated virus vector.
Topics: beta-Galactosidase; Cells, Cultured; Dependovirus; Gene Transfer Techniques; Genetic Vectors; Humans | 2003 |
Heparin stimulates production of bFGF and TGF-beta 1 by human normal, keloid, and fetal dermal fibroblasts.
Topics: Cell Division; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Fetus; | 2003 |
Immunohistochemical analysis of Fas protein expression in hypertrophic scar and keloid.
Topics: Cicatrix, Hypertrophic; Diagnosis, Differential; fas Receptor; Humans; Immunohistochemistry; Keloid | 2003 |
Keloidal scleroderma.
Topics: Administration, Topical; Anti-Inflammatory Agents; Beclomethasone; Calcitriol; Dermatologic Agents; | 2003 |
Suppression of insulin-like growth factor signalling pathway and collagen expression in keloid-derived fibroblasts by quercetin: its therapeutic potential use in the treatment and/or prevention of keloids.
Topics: Blotting, Northern; Blotting, Western; Cell Division; Cells, Cultured; Collagen; Dose-Response Relat | 2003 |
[The distributing characteristics and proliferating activity of fibroblasts from the surrounding skin of keloids].
Topics: Adolescent; Adult; Cell Division; Cells, Cultured; Female; Fibroblasts; Humans; Keloid; Male; Skin | 2002 |
Painless steroid injections for hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Humans; Injections; Keloid; Pain; Steroids | 2003 |
Increased plasminogen activator inhibitor-1 in keloid fibroblasts may account for their elevated collagen accumulation in fibrin gel cultures.
Topics: Adolescent; Adult; Cell Culture Techniques; Cells, Cultured; Child; Child, Preschool; Cicatrix; Coll | 2003 |
Intralesional cryotherapy for enhancing the involution of hypertrophic scars and keloids.
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix, Hypertrophic; Collagen; Cryosurgery; Female; H | 2003 |
Intralesional cryotherapy for enhancing the involution of hypertrophic scars and keloids.
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix, Hypertrophic; Collagen; Cryosurgery; Female; H | 2003 |
Intralesional cryotherapy for enhancing the involution of hypertrophic scars and keloids.
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix, Hypertrophic; Collagen; Cryosurgery; Female; H | 2003 |
Intralesional cryotherapy for enhancing the involution of hypertrophic scars and keloids.
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix, Hypertrophic; Collagen; Cryosurgery; Female; H | 2003 |
Treatment of keloids by surgical excision and immediate postoperative single-fraction radiotherapy.
Topics: Adolescent; Adult; Child; Female; Follow-Up Studies; Humans; Keloid; Male; Radiotherapy Dosage; Radi | 2003 |
Goeminne syndrome (OMIM 314300): another male patient 30 years later.
Topics: Abnormalities, Multiple; Adult; Cervical Vertebrae; Chromosomes, Human, X; Cryptorchidism; Follow-Up | 2003 |
[Hypertrophic eyelid conjunctival scar. A tarsal keloid].
Topics: Cicatrix; Conjunctiva; Eyelid Neoplasms; Female; Humans; Hypertrophy; Keloid; Middle Aged; Time Fact | 2003 |
[Scarring, a complex phenomenon].
Topics: Cicatrix; Humans; Inflammation; Keloid | 2003 |
Role of HLA-DR and CD1a molecules in pathogenesis of hypertrophic scarring and keloids.
Topics: Antigens, CD1; Cicatrix, Hypertrophic; HLA-DR Antigens; Humans; Keloid; Triamcinolone Acetonide | 2003 |
Insulin-like growth factor-I enhances transforming growth factor-beta-induced extracellular matrix protein production through the P38/activating transcription factor-2 signaling pathway in keloid fibroblasts.
Topics: 3T3 Cells; Activating Transcription Factor 2; Adolescent; Adult; Aged; Animals; Cells, Cultured; Chi | 2003 |
IFN-gamma fails to antagonize fibrotic effect of TGF-beta on keloid-derived dermal fibroblasts.
Topics: Actins; Blotting, Western; Case-Control Studies; Cells, Cultured; Collagen; Collagen Type I; Fibrobl | 2003 |
Dietary compounds inhibit proliferation and contraction of keloid and hypertrophic scar-derived fibroblasts in vitro: therapeutic implication for excessive scarring.
Topics: Adolescent; Biological Assay; Burns; Cell Division; Cells, Cultured; Cicatrix, Hypertrophic; Collage | 2003 |
Keloid in Iraqi patients: a clinicohistopathologic study.
Topics: Adolescent; Adult; Age Distribution; Aged; Child; Child, Preschool; Female; Humans; Iraq; Keloid; Ma | 2003 |
Three-year retrospective review of superficial radiotherapy for skin conditions in a Perth radiotherapy unit.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Humans; Kel | 2003 |
Keloid-like scleroderma.
Topics: Actins; Elastic Tissue; Female; Fibroblasts; Fibrosis; Humans; Immunohistochemistry; Keloid; Middle | 2003 |
[Cell cycle analysis and P53 gene mutation detection of fibroblasts derived from the surrounding skin of keloids].
Topics: Cell Cycle; Cell Division; Cells, Cultured; Exons; Fibroblasts; Frameshift Mutation; Genes, p53; Hum | 2003 |
Treatment of an earlobe keloid. Finding the evidence.
Topics: Adolescent; Evidence-Based Medicine; Female; Glucocorticoids; Humans; Keloid; Secondary Prevention | 2003 |
Synchronous activation of ERK and phosphatidylinositol 3-kinase pathways is required for collagen and extracellular matrix production in keloids.
Topics: Blotting, Western; Butadienes; Cell Division; Chromones; Coculture Techniques; Collagen; Culture Med | 2003 |
A wound contraction experimental model for studying keloids and wound-healing modulators.
Topics: Cells, Cultured; Collagen; Fibroblast Growth Factors; Fibroblasts; Humans; Keloid; Microscopy, Elect | 2003 |
Control of an outbreak of BCG complications in Gaza.
Topics: Adjuvants, Immunologic; BCG Vaccine; Disease Outbreaks; Humans; Infant; Infant, Newborn; Keloid; Lym | 2003 |
What is nodular-keloidal scleroderma?
Topics: Fibrosis; Humans; Keloid; Scleroderma, Localized; Scleroderma, Systemic; Skin | 2003 |
Polymorphic fibrosing reaction mimicking keloidal scleroderma but without associated classic scleroderma.
Topics: Adult; Female; Fibrosis; Humans; Hyperpigmentation; Keloid; Scleroderma, Localized; Scleroderma, Sys | 2003 |
Rembrandt's left ear.
Topics: Ear Deformities, Acquired; Famous Persons; History, 17th Century; Humans; Keloid; Paintings | 2003 |
Analysis of differentially expressed genes in keloids and normal skin with cDNA microarray.
Topics: Adult; Child, Preschool; Female; Gene Expression; Gene Expression Profiling; Humans; Keloid; Male; N | 2003 |
[Keloid following electrocoagulation, treated by radium].
Topics: Electrocoagulation; Fibroma; Keloid; Radium | 1952 |
[Comparison of the keloid, scleredema and myxedema].
Topics: Humans; Keloid; Myxedema; Scleredema Adultorum; Skin Diseases | 1952 |
[Keloids in vaccination and revaccination].
Topics: Fibroma; Immune System Diseases; Immunization, Secondary; Keloid; Vaccination; Vaccines | 1952 |
[Melanoma treated at the initial site with formation of a keloid scar, with residual lymph node metastases].
Topics: Cicatrix; Humans; Keloid; Lymph Nodes; Lymphatic Metastasis; Melanoma | 1952 |
Hypertrophic scars and keloids.
Topics: Cicatrix; Cicatrix, Hypertrophic; Fibroma; Humans; Keloid; Wounds and Injuries | 1953 |
[Keloid and ultrasonic therapy; preliminary communication].
Topics: Communication; Fibroma; Humans; Keloid; Ultrasonic Therapy; Ultrasonics | 1952 |
Cortisone as an adjunct to surgery in the treatment of keloids.
Topics: Cortisone; Fibroma; Keloid | 1953 |
Keloid, a hazard of piercing for ear-rings.
Topics: Ear Neoplasms; Fibroma; Humans; Keloid; Tinnitus | 1953 |
Malignant change in keloids.
Topics: Fibroma; Keloid | 1953 |
[Medico-surgical problems in dermatology; report of some observations made in U.S.A. on the treatment of keloid, angioma, radio-dermatitis, naevus planus, naevus carcinoma and epithelioma of the face].
Topics: Dermatitis; Dermatology; Hemangioma; Humans; Keloid; Nevus; Nevus, Pigmented; Skin Diseases; Skin Ne | 1953 |
[Surgical therapy of cicatricial keloid].
Topics: Cicatrix; Fibroma; Humans; Keloid | 1953 |
[Cortisone in the cure of keloids].
Topics: Cortisone; Fibroma; Keloid | 1953 |
Investigations into the role of heparin in proliferative tissue reactions. I. Increased heparin tolerance in patients with burns and keloids.
Topics: Burns; Fibroma; Heparin; Humans; Keloid | 1953 |
[Remarks on A. Vogl's paper, Surgery of scar keloid].
Topics: Cicatrix; Fibroma; Humans; Keloid | 1953 |
Reactions of healing wounds and granulation tissue in man to auto-Thiersch, autodermal, and homodermal grafts: with an analysis of the implications of the phenomena encountered for an understanding of the behaviour of grafted tissue and the genesis of sca
Topics: Cicatrix; Granulation Tissue; Humans; Keloid; Male; Skin Diseases; Skin Transplantation; Transplants | 1953 |
[Keloids scattered over the thorax following a postpartum eruption of undetermined nature].
Topics: Exanthema; Female; Fibroma; Humans; Keloid; Postpartum Period; Skin Diseases; Thorax | 1953 |
The treatment of keloids and keloidal scars.
Topics: Cicatrix; Fibroma; Humans; Keloid | 1953 |
[Therapy of keloid].
Topics: Fibroma; Keloid | 1953 |
ACTH and cortisone in the treatment of keloids.
Topics: Adrenocorticotropic Hormone; Cortisone; Fibroma; Keloid | 1954 |
Treatment of keloids with hyaluronidase.
Topics: Fibroma; Hyaluronoglucosaminidase; Keloid | 1954 |
[Keloids and their treatment with special reference to the radiotherapy].
Topics: Fibroma; Humans; Keloid; Radiotherapy; Radium | 1954 |
[The genesis of the so-called idiopathic keloid].
Topics: Diethylstilbestrol; Fibroma; Humans; Keloid | 1954 |
The treatment of keloids with a combination of hyaluronidase and kutapressin.
Topics: Antimicrobial Cationic Peptides; Fibroma; Humans; Hyaluronoglucosaminidase; Keloid; Liver Extracts; | 1954 |
[Keloid-like scleroderma, with remarks on phase variation of certain sclerodermic diseases].
Topics: Basidiomycota; Fibroma; Humans; Keloid; Scleroderma, Localized; Scleroderma, Systemic | 1954 |
Prophylaxis of surgical keloids.
Topics: Fibroma; Keloid | 1954 |
The management of keloid in the South African Bantu.
Topics: Black People; Disease Management; Fibroma; Humans; Keloid; Radiotherapy | 1954 |
[Therapy of keloid scars with grenz rays].
Topics: Cicatrix; Fibroma; Humans; Keloid; Radiotherapy; X-Rays | 1954 |
[Case report on local treatment of keloid with heparin].
Topics: Complement System Proteins; Fibroma; Heparin; Humans; Keloid | 1955 |
An unusual case of keloidal scars of the ears.
Topics: Cicatrix; Ear, External; Fibroma; Head and Neck Neoplasms; Humans; Keloid | 1955 |
[Clinical aspects of the keloid].
Topics: Fibroma; Humans; Keloid; Radiotherapy | 1955 |
[Local injections of hydrocortisone acetate in therapy of keloid].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Fibroma; Hydrocortisone; Injections; Keloid | 1955 |
Treatment of keloids with topical injections of hydrocortisone acetate.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Fibroma; Humans; Hydrocortisone; Injections; Keloid | 1956 |
[Prevention of postoperative keloid].
Topics: Biomedical Research; Fibroma; Humans; Keloid; Postoperative Period | 1955 |
Heredity of keloids; review of the literature and report of a family with multiple keloids in five generations.
Topics: Fibroma; Heredity; Humans; Keloid | 1956 |
[Combined macronitherapy and radiotherapy in the treatment of keloids caused by burns].
Topics: Burns; Electric Stimulation Therapy; Fibroma; Humans; Keloid; Radiotherapy | 1955 |
Surgical planing of the skin; dichlorotetrafluoro-ethane as a freezing agent.
Topics: Aircraft; Anesthetics; Anesthetics, Local; Blast Injuries; Cicatrix; Cicatrix, Hypertrophic; Dermato | 1956 |
KELOIDS.
Topics: Fibroma; Keloid | 1956 |
KELOIDS.
Topics: Fibroma; Keloid | 1956 |
[The cicatricial keloid; pathogenesis, significance, diagnostic value].
Topics: Fibroma; Keloid | 1956 |
[Inclination to keloid formation and cosmetic surgery].
Topics: Cosmetics; Fibroma; Humans; Keloid; Plastics; Surgery, Plastic | 1956 |
[Results of plesioradiography of keloids].
Topics: Fibroma; Humans; Keloid; Radiotherapy | 1956 |
[Results of plesioradiography of keloids].
Topics: Fibroma; Humans; Keloid; Radiotherapy | 1956 |
[Results of plesioradiography of keloids].
Topics: Fibroma; Humans; Keloid; Radiotherapy | 1956 |
[Results of plesioradiography of keloids].
Topics: Fibroma; Humans; Keloid; Radiotherapy | 1956 |
[Several considerations of medicosurgical nature related to the treatment of cicatricial keloids, fibrokeloids, and fibrohyalins; personal experience].
Topics: Fibroma; Keloid | 1956 |
[Several considerations of medicosurgical nature related to the treatment of cicatricial keloids, fibrokeloids, and fibrohyalins; personal experience].
Topics: Fibroma; Keloid | 1956 |
[Several considerations of medicosurgical nature related to the treatment of cicatricial keloids, fibrokeloids, and fibrohyalins; personal experience].
Topics: Fibroma; Keloid | 1956 |
[Several considerations of medicosurgical nature related to the treatment of cicatricial keloids, fibrokeloids, and fibrohyalins; personal experience].
Topics: Fibroma; Keloid | 1956 |
Keloids of the ears.
Topics: Disease; Ear Diseases; Ear, External; Fibroma; Humans; Hyaluronoglucosaminidase; Keloid | 1956 |
Keloids of the ears.
Topics: Disease; Ear Diseases; Ear, External; Fibroma; Humans; Hyaluronoglucosaminidase; Keloid | 1956 |
Keloids of the ears.
Topics: Disease; Ear Diseases; Ear, External; Fibroma; Humans; Hyaluronoglucosaminidase; Keloid | 1956 |
Keloids of the ears.
Topics: Disease; Ear Diseases; Ear, External; Fibroma; Humans; Hyaluronoglucosaminidase; Keloid | 1956 |
[Treatment of cicatricial keloids by irradiation].
Topics: Humans; Keloid; Radiotherapy | 1956 |
[Treatment of cicatricial keloids by irradiation].
Topics: Humans; Keloid; Radiotherapy | 1956 |
[Treatment of cicatricial keloids by irradiation].
Topics: Humans; Keloid; Radiotherapy | 1956 |
[Treatment of cicatricial keloids by irradiation].
Topics: Humans; Keloid; Radiotherapy | 1956 |
Multiple keloids.
Topics: Fibroma; Keloid | 1957 |
The treatment of keloids.
Topics: Fibroma; Hyaluronoglucosaminidase; Hydrocortisone; Keloid; Radiotherapy | 1957 |
[Successful thiosinamine therapy of cicatricial keloid].
Topics: Fibroma; Humans; Keloid; Thiourea | 1957 |
[Treatment of keloids].
Topics: Fibroma; Hydrocortisone; Keloid; Radiotherapy | 1957 |
[Keloid formation after revaccination of uniovular twins].
Topics: Disease; Diseases in Twins; Fibroma; Immunization, Secondary; Keloid; Twins; Twins, Monozygotic; Vac | 1957 |
Keloid.
Topics: Female; Humans; Keloid; Leiomyoma; Uterine Neoplasms | 1957 |
[Treatment of keloids with local infiltration of hyaluronidase combined with radiotherapy].
Topics: Fibroma; Hyaluronoglucosaminidase; Keloid; Radiotherapy | 1957 |
[Radiotherapy of keloids].
Topics: Fibroma; Keloid; Radiotherapy | 1957 |
[Use of hydrocortisone ointment in the treatment of keloids].
Topics: Fibroma; Humans; Hydrocortisone; Keloid; Skin Neoplasms | 1957 |
[Treatment of keloids by nitrogen mustard derivatives].
Topics: Busulfan; Fibroma; Humans; Keloid; Mechlorethamine; Nitrogen Mustard Compounds | 1957 |
[Comparative trials of paper chromatography of normal skin & keloid tissue].
Topics: Amino Acids; Chromatography, Paper; Fibroma; Humans; Keloid; Peptides | 1957 |
[Treatment of keloids. I. Chemical and surgical treatment possibilities].
Topics: Fibroma; Keloid | 1958 |
[Split thickness skin grafts in keloid therapy].
Topics: Fibroma; Humans; Keloid; Skin Transplantation | 1958 |
[Cicatricial keloids & cholesterol foreign body granuloma of cornea].
Topics: Cholesterol; Cornea; Granuloma, Foreign-Body; Humans; Keloid | 1958 |
[Keloids and their treatment by radiotherapy].
Topics: Fibroma; Keloid; Radiotherapy | 1958 |
Oral treatment of keloids.
Topics: Administration, Oral; Fibroma; Keloid; Quinones | 1958 |
[Studies on keloid tissue].
Topics: Fibroma; Keloid | 1958 |
Non-surgical reduction of granuloma and keloids.
Topics: Fibroma; Foot; Foot Diseases; Granuloma; Humans; Hydrocortisone; Keloid; Neoplasms; Syndrome | 1958 |
[Contribution to the origin of keloids with respect to its histochemistry].
Topics: Fibroma; Keloid | 1958 |
[Suggestion on a point of technic relative to the treatment of keloids].
Topics: Fibroma; Humans; Keloid; Suggestion | 1958 |
[Studies on keloid therapy].
Topics: Fibroma; Hydrocortisone; Keloid | 1958 |
[Notes on three cases of perineo-vaginal keloid manifestations].
Topics: Female; Fibroma; Humans; Keloid; Medical Records; Neoplasms; Perineum; Vaginal Neoplasms | 1958 |
[Keloids and c'catricial hypertrophy].
Topics: Fibroma; Humans; Hypertrophy; Keloid | 1958 |
The uterus and the products of inflammation: fundal keloid.
Topics: Disease; Female; Humans; Inflammation; Keloid; Uterine Diseases; Uterus | 1959 |
[Etiologic and therapeutic problems of keloids].
Topics: Fibroma; Keloid | 1959 |
The effects of topical applications of cortisone-antibiotic ointment on surgical incisions and keloid formation.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cortisone; Dermatologic Agents; Humans; Keloid; | 1959 |
Aminoacid content of keloid.
Topics: Amino Acids; Keloid | 1960 |
Hemagglutinative vaso-occlusion in the pathodynamics of keloid.
Topics: Capillaries; Hemagglutination; Humans; Keloid | 1961 |
Mast cells in keloids.
Topics: Humans; Keloid; Mast Cells | 1961 |
[On the prevention of keloid formation].
Topics: Amine Oxidase (Copper-Containing); Burns; Humans; Keloid | 1961 |
The ultrastructure of collagen in skin, scars and keloids.
Topics: Cicatrix; Collagen; Humans; Keloid; Skin | 1961 |
[On radiotherapy of hemangiomas and keloids].
Topics: Hemangioma; Humans; Keloid | 1961 |
[1st impressions on the oral treatment of Mienicki's keloids (vitamins C, B 2, PP and iron). Apropos of 20 cases. (Preliminary note)].
Topics: Administration, Oral; Ascorbic Acid; Chlorophenols; Humans; Iron; Keloid; Nutrition Therapy; Vitamin | 1961 |
[Experimental studies in connection with changes in reactive capacity of the connective tissue after burns. (Data on the problem of the development of a tendency to keloids)].
Topics: Burns; Connective Tissue; Keloid | 1961 |
Keloids from dermal testing in an allergic patient.
Topics: Child; Humans; Hypersensitivity; Immune System Diseases; Infant; Keloid; Skin Tests | 1961 |
[Dupuytren's contracture in all 4 extremities, induratio penis plastica, periarthritis humeroscapularis, keloids and pads on the finger knuckles].
Topics: Disease; Dupuytren Contracture; Extremities; Fingers; Humans; Keloid; Male; Penile Diseases; Penis; | 1960 |
Keloids: etiology, and management by excision and intensive prophylactic radiation.
Topics: Disease Management; Humans; Keloid | 1959 |
Hypertrophic scars and keloids. Etiology, pathogenesis and dermatologic therapy.
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid | 1960 |
Keloid following antibiotic powder spray.
Topics: Anti-Bacterial Agents; Humans; Keloid | 1959 |
[A contribution to nodular scleroderma (keloid-like scleroderma Unna)].
Topics: Humans; Keloid; Medical Records; Scleroderma, Localized; Scleroderma, Systemic | 1960 |
[Keloids as a form of auto-aggression in the scar].
Topics: Aggression; Cicatrix; Fibroma; Humans; Keloid; Neoplasms | 1960 |
Differential diagnosis of keloids and hypertrophic scars by tissue culture technique with notes on therapy of keloids by surgical excision and decadron.
Topics: Cicatrix; Cicatrix, Hypertrophic; Cortisone; Dexamethasone; Diagnosis, Differential; Humans; Keloid; | 1960 |
Observations on the behavior of human keloids in vitro.
Topics: Fibroma; In Vitro Techniques; Keloid | 1959 |
[The use of heparinoids to prevent defective cicatrix in plastic surgery of the eyelids].
Topics: Cicatrix; Eyelids; Heparinoids; Hirudin Therapy; Hirudins; Humans; Keloid; Plastic Surgery Procedure | 1960 |
Carcinoma with adenomatous structure in skin transplanted in the region of keloid acne of the neck.
Topics: Acne Vulgaris; Carcinoma; Head and Neck Neoplasms; Humans; Keloid; Neoplasms; Skin; Skin Transplanta | 1960 |
[Experiences with new methods of keloid therapy].
Topics: Humans; Hyaluronoglucosaminidase; Hydrocortisone; Keloid | 1959 |
[On the therapy of keloids].
Topics: Hydrocortisone; Keloid; Neomycin; Prednisolone | 1959 |
Radiation in the management of keloids and hypertrophic scars.
Topics: Cicatrix, Hypertrophic; Humans; Keloid | 1960 |
[Treatment of keloids with intrakeloid decadron 21-phosphate].
Topics: Dexamethasone; Humans; Keloid; Phosphates; Prednisolone | 1959 |
[On the problem of cicatrix formation with special reference to keloid formation].
Topics: Cicatrix; Keloid | 1960 |
Tissue culture studies of keloids.
Topics: Humans; Keloid | 1959 |
A case of tracheal obstruction by an endotracheal keloidal papilloma, following tracheostomy for neonatal laryngeal insufficiency. Excision after five years of tracheostomy life.
Topics: Airway Obstruction; Child; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Keloid; Neopl | 1961 |
Xanthofibroma of stomach.
Topics: Histiocytoma, Benign Fibrous; Humans; Keloid; Medical Records; Stomach Neoplasms | 1962 |
Pyoderma associated with keloids; infestation with fusopirillary organisms.
Topics: Communicable Diseases; Fusobacterium; Fusobacterium Infections; Humans; Keloid; Medical Records; Par | 1961 |
[Our experience in the treatment of keloid cicatrix and keloids with hydrocortisone acetate].
Topics: Cicatrix; Humans; Hydrocortisone; Keloid | 1962 |
[Experiences with podophyllin therapy in laryngeal papilloma. (Comparative observations on cases treated with and without podophyllin)].
Topics: Humans; Keloid; Laryngeal Neoplasms; Larynx; Papilloma; Papillomavirus Infections; Podophyllin; Podo | 1961 |
[Attempted treatment of pigmentary, vascular and keloid changes with vibropuncture].
Topics: Hemangioma; Humans; Keloid; Pigmentation Disorders; Telangiectasis | 1962 |
[Laryngeal papilloma and laryngeal carcinoma].
Topics: Humans; Keloid; Laryngeal Neoplasms; Larynx; Papilloma; Papillomavirus Infections | 1961 |
[Cortisol and keloid prophylaxis].
Topics: Humans; Hydrocortisone; Keloid | 1962 |
[Ultrasonics therapy of keloids].
Topics: Humans; Keloid; Ultrasonic Therapy; Ultrasonics | 1961 |
[Clinical aspects and treatment of papilloma of the larynx especially in adults].
Topics: Humans; Keloid; Laryngeal Neoplasms; Larynx; Papilloma | 1961 |
[Cicatricial keloids and their treatment].
Topics: Cicatrix; Humans; Hydrocortisone; Keloid; Plants, Medicinal | 1961 |
[Application of scar and scar keloid in the field of plastic surgery].
Topics: Cicatrix; Humans; Keloid; Plastic Surgery Procedures; Plastics; Skin Transplantation; Surgery, Plast | 1961 |
[Actinotherapy of keloids].
Topics: Humans; Keloid; Phototherapy; Ultraviolet Rays; Ultraviolet Therapy | 1961 |
[Concerning diverse applications of a heparinmucopolysaccharidase combination].
Topics: Glycoside Hydrolases; Hematoma; Hemorrhoids; Heparin; Humans; Keloid; Phlebitis; Purpura | 1963 |
Kenalog and the treatment of hypertrophied scars and keloids in Negroes and whites.
Topics: Black People; Cicatrix; Humans; Hypertrophy; Keloid; Triamcinolone Acetonide | 1963 |
Dermatological photography.
Topics: Africa; Africa, Eastern; Anthrax; Black People; Dermatology; Erythema Multiforme; Herpes Zoster; Hum | 1963 |
Iconographia dermatologica. 10. (Special issue for fibroblastic tumors).
Topics: Fibroblasts; Fibroma; Fibrosarcoma; Humans; Keloid; Neoplasms | 1962 |
Treatment of keloid with asiaticoside.
Topics: Humans; Keloid; Terpenes; Triterpenes | 1962 |
[The keloid reaction as the cause of bile duct stricture].
Topics: Cholestasis; Common Bile Duct; Constriction, Pathologic; Humans; Keloid | 1962 |
[Posttraumatic dermatological complications].
Topics: Dermatitis; Humans; Hypersensitivity; Keloid; Radiation Injuries; Wound Healing; Wounds and Injuries | 1962 |
[Does the administration of histaminase prevent keloid formation after burns?].
Topics: Amine Oxidase (Copper-Containing); Burns; Humans; Keloid | 1963 |
[The keloid and its therapy].
Topics: Humans; Hyaluronoglucosaminidase; Hydrocortisone; Keloid | 1962 |
An unusual case of acne keloid.
Topics: Acne Keloid; Acne Vulgaris; Humans; Keloid; Leprosy | 1962 |
Preliminary studies on the effect of time-dose patterns in the treatment of keloids.
Topics: Humans; Keloid; Radiotherapy | 1963 |
[Keloids].
Topics: Humans; Keloid | 1963 |
Colour, cancer, and keloids in the Sudan.
Topics: Black People; Color; Humans; Keloid; Neoplasms; Pigmentation Disorders; Sudan | 1962 |
[Local therapy with 6-methylprednisolone (Urbason)].
Topics: Bursitis; Dupuytren Contracture; Humans; Joint Diseases; Keloid; Methylprednisolone; Tendinopathy | 1962 |
The effects of tetrahydroxyquinone on connective tissue.
Topics: Connective Tissue; Humans; Keloid; Quinones | 1963 |
MALIGNANT TRANSFORMATION OF BENIGN LARYNGEAL PAPILLOMAS IN CHILDREN AFTER RADIATION THERAPY.
Topics: Carcinoma; Carcinoma, Squamous Cell; Child; Keloid; Laryngeal Neoplasms; Neoplasms; Pathology; Radia | 1963 |
VOCAL-CORK SURGERY.
Topics: Biopsy; Cysts; Granuloma; Humans; Keloid; Laryngeal Neoplasms; Laryngoscopy; Leukoplakia; Surgical P | 1963 |
ELECTRON MICROSCOPIC STUDY OF HUMAN LARYNGEAL PAPILLOMATOSIS.
Topics: Adolescent; Biopsy; Child; Electrons; Humans; Keloid; Laryngeal Neoplasms; Microscopy; Microscopy, E | 1963 |
HISTOCHEMISTRY OF THE ACID MUCOPOLYSACCHARIDES OF SKIN IN NORMAL AND IN CERTAIN PATHOLOGIC CONDITIONS.
Topics: Adenocarcinoma, Mucinous; Calcinosis; Classification; Coloring Agents; Glycosaminoglycans; Histocyto | 1963 |
THE TREATMENT OF SKIN CONDITIONS IN THE RADIOTHERAPY DEPARTMENT.
Topics: Acne Vulgaris; Geriatrics; Hair Removal; Humans; Keloid; Keratosis; Neoplasms; Pruritus; Radiotherap | 1963 |
LOCAL REACTIONS AFTER BCG VACCINATION.
Topics: Adolescent; BCG Vaccine; Child; China; Humans; Keloid; Mycobacterium bovis; Toxicology; Vaccination | 1963 |
[THE TREATMENT OF BENIGN NEOPLASMS AND HYPERPLASIAS OF THE SKIN WITH CRITICAL OBSERVATIONS ON RADIOTHERAPY].
Topics: Angiokeratoma; Carcinoma, Adenoid Cystic; Dupuytren Contracture; Eosinophilic Granuloma; Epidermal C | 1963 |
[INTRALESIONAL EFFECTS OF BETAMETHASONE WITH SPECIAL REFERENCE TO ITS HISTOPATHOLOGIC STUDY].
Topics: Acne Vulgaris; Betamethasone; Humans; Injections; Keloid; Leprosy; Lichen Planus; Lupus Erythematosu | 1963 |
[PROSPECTS OF BIOPHYSICAL INVESTIGATIONS IN THE STUDY OF KELOIDS].
Topics: Amino Acids; Chromatography; Collagen; Electrons; Histocytochemistry; Keloid; Microscopy; Microscopy | 1963 |
TRIAMCINOLONE ACETONIDE INJECTED SUBLESIONALLY IN THE TREATMENT OF DERMATOSES.
Topics: Asian People; Black People; Dermatitis; Dermatology; Eczema; Geriatrics; Granuloma; Humans; Keloid; | 1963 |
XANTHOFIBROMA OF THE STOMACH. REPORT OF A CASE WITH SEVERE SECONDARY HYPOCHROMIC ANEMIA.
Topics: Anemia, Hypochromic; Anemia, Sideroblastic; Genetic Diseases, X-Linked; Humans; Keloid; Pathology; S | 1963 |
CLINICAL EVALUATION OF A STEROID-VITAMIN A-ESTROGEN LOTION.
Topics: Acne Vulgaris; Alopecia Areata; Dermatitis; Dermatitis, Atopic; Dermatology; Estrogens; Humans; Hydr | 1963 |
A RARE CASE OF SARCOMATOUS DEGENERATION OF A CHELOID.
Topics: Abdominal Neoplasms; Autopsy; Fibrosarcoma; Humans; Hydrocortisone; Keloid; Neoplasm Metastasis; Neo | 1963 |
TETRAHYDROXYQUINONE (THQ) EFFECTS ON SPONGE IMPLANTS IN THE ALBINO RAT.
Topics: Animals; Connective Tissue; Estrone; Foreign Bodies; Keloid; Polyvinyls; Porifera; Prostheses and Im | 1964 |
[SECONDARY EFFECTS, SYMPTOMS AND UNDESIRABLE EARLY SEQUELAE IN SURGERY OF THE ABDOMINAL CAVITY. GENERAL PATHOLOGICAL AND CLINICAL PROBLEMS].
Topics: Abdomen; Abdominal Cavity; Anuria; Blood Glucose; Enterocolitis; Humans; Keloid; Laparotomy; Pain; P | 1963 |
[RESEARCH ON THE NATURE AND ULTRASTRUCTURE OF KELOIDS. I. HISTOLOGICAL AND POLAROSCOPIC INVESTIGATIONS].
Topics: Electrons; Histological Techniques; Histology; Keloid; Microscopy; Microscopy, Electron; Research | 1963 |
[RESEARCH ON THE NATURE AND ULTRASTRUCTURE OF KELOIDS. II. DIFFRACTOGRAPHIC AND ELECTRON MICROSCOPIC STUDIES].
Topics: Collagen; Crystallography; Electrons; Keloid; Microscopy; Microscopy, Electron | 1963 |
[RESEARCH ON THE NATURE AND ULTRASTRUCTURE OF KELOIDS. III. CHEMICAL ANALYSIS].
Topics: Chemical Phenomena; Chemistry; Chromatography; Collagen; Hydroxyproline; Keloid; Proteins; Research | 1963 |
A CASE OF IDIOPATHIC RETROPERITONEAL FIBROSIS PRESENTING AS A SYSTEMIC COLLAGEN DISEASE.
Topics: Adolescent; Autoimmune Diseases; Blood Protein Disorders; Blood Transfusion; Chloroquine; Collagen D | 1964 |
THE ROLE OF RADIATION THERAPY IN SOME BENIGN CONDITIONS.
Topics: Adenoids; Arthritis; Dermatology; Hemangioma; Humans; Keloid; Lymph Nodes; Neuralgia; Parotitis; Rad | 1964 |
BURN CONTRACTURE OF THE NECK.
Topics: Bandages; Burns; Child; Contracture; Humans; Keloid; Neck; Skin Transplantation; Splints | 1964 |
[EXPERIENCES WITH INTRALESIONAL CORTICOSTEROID TREATMENT OF SEVERAL SKIN DISEASES].
Topics: Adrenal Cortex Hormones; Alopecia Areata; Cheilitis; Eczema; Granuloma; Humans; Injections; Keloid; | 1964 |
[PREVENTION OF FAULTY CICATRICES IN ESTHETIC SURGERY].
Topics: Biomedical Research; Cicatrix; Glycoside Hydrolases; Heparin; Humans; Keloid; Surgery, Plastic; Surg | 1964 |
SALT-INDUCED VAGINAL STENOSIS OF ARABIA.
Topics: Arabia; Coitus; Constriction, Pathologic; Cortisone; Female; Humans; Infertility; Keloid; Menstruati | 1964 |
PROTEOLYTIC ENZYMES IN WOUND REPAIR; IMMEDIATE POSTOPERATIVE EFFECTS.
Topics: Biomedical Research; Drug Therapy; Edema; Hematoma; Humans; Keloid; Pain; Peptide Hydrolases; Postop | 1964 |
RADIOTHERAPY OF LESIONS OF THE LIDS.
Topics: Conjunctiva; Conjunctivitis; Cornea; Eyelashes; Eyelids; Humans; Keloid; Lens, Crystalline; Lymphoma | 1964 |
[KELOIDS AND THEIR TREATMENT].
Topics: Humans; Keloid; Radium; Surgical Procedures, Operative | 1964 |
[LOCAL USE OF CORTICOIDS IN BURNS AND SURGICAL SCARS].
Topics: Administration, Topical; Adrenal Cortex Hormones; Burns; Cicatrix; Hydrocortisone; Keloid; Neomycin; | 1963 |
TREATMENT OF KELOIDS BY STEROIDS WITH BIOCHEMICAL TESTS FOR DIAGNOSIS AND PROGNOSIS.
Topics: Blood Protein Electrophoresis; Blood Sedimentation; Child; Clinical Laboratory Techniques; Dexametha | 1964 |
REGIONAL KELOID SUSCEPTIBILITY.
Topics: Africa; Africa, Eastern; Black People; Cicatrix; Diagnosis, Differential; Genitalia; Head; Humans; H | 1964 |
CUTANEOUS COMPLICATIONS OF MASS VACCINATION AGAINST SMALLPOX IN SOUTH WALES 1962.
Topics: Adolescent; Child; Communicable Diseases; Female; Fetal Diseases; Hematologic Diseases; Humans; Infa | 1964 |
EFFECT OF THYROTROPIC HORMONE ON GRANULATION TISSUE.
Topics: Electrophoresis; Exudates and Transudates; Gonadotropins; Granulation Tissue; Hexosamines; Inflammat | 1964 |
NEGRO SKIN.
Topics: Black People; Histological Techniques; Histology; Humans; Keloid; Sarcoidosis; Skin | 1964 |
[FURTHER STUDIES ON THE NATURE OF THE VIRUS ISOLATED IN POSTVACCINAL VIREMIA. IV].
Topics: Animals; Chick Embryo; Keloid; Lagomorpha; Rabbits; Research; Smallpox Vaccine; Variola virus; Viral | 1964 |
[INOCULATIONS IN HAMSTERS OF SOUTH AMERICAN BLASTOMYCOSIS (LUTZ'S DISEASE), KELOID-LIKE BLASTOMYCOSIS (LOBO'S DISEASE) AND BLASTOMYCOSIS FROM THE INDIANS OF TAPAJ'OS-XINGU].
Topics: Animals; Blastomycosis; Brazil; Cricetinae; Hispanic or Latino; Humans; Indians, South American; Kel | 1964 |
[GARDNER SYNDROME].
Topics: Colonic Neoplasms; Cysts; Exostoses; Gardner Syndrome; Genetics, Medical; Keloid; Pathology; Polyps; | 1964 |
ISOTONIC AND ISOMETRIC THERMAL CONTRACTION OF HUMAN DERMIS. 3. SCLERODERMA AND CICATRIZING LESIONS.
Topics: Cicatrix; Dermatologic Agents; Dermis; Hot Temperature; Humans; Isometric Contraction; Keloid; Physi | 1964 |
COLLAGEN SYNTHESIS BY HUMAN FIBROBLAST STRAINS.
Topics: Child; Collagen; Fetus; Fibroblasts; Humans; Hydroxyproline; Keloid; Lung; Proline; Proteins; Resear | 1964 |
THE AETIOLOGY OF KELOIDS: A REVIEW OF THE LITERATURE AND A NEW HYPOTHESIS.
Topics: Acromegaly; Black People; Cicatrix; Drug Therapy; Foreign Bodies; Humans; Hydrocortisone; Hyperthyro | 1964 |
[ON ADVANCES IN LOCAL HEPARINOID TREATMENT].
Topics: Drug Therapy; Geriatrics; Hematoma; Heparinoids; Humans; Keloid; Leg Ulcer; Thrombophlebitis; Varico | 1964 |
HYPERTROPHIC CORNEAL SCARS (KELOIDS).
Topics: Black People; Child; Cicatrix, Hypertrophic; Cornea; Corneal Injuries; Eye Injuries; Eye Neoplasms; | 1964 |
[EXCISION OF NEVI IN CHILDHOOD].
Topics: Child; Humans; Keloid; Nevus; Nevus, Pigmented; Skin Neoplasms; Surgical Procedures, Operative | 1964 |
[MORPHOLOGICAL AND HISTOCHEMICAL STUDY OF KELOIDS].
Topics: Histocytochemistry; Humans; Keloid; Pathology | 1964 |
[TREATMENT OF KELOID CICATRIX WITH ULTRASOFT ROENTGEN RAYS].
Topics: Cicatrix; Humans; Keloid; Radiotherapy; X-Rays | 1964 |
[THE TREATMENT OF KELOID].
Topics: Drug Therapy; Humans; Keloid | 1964 |
[LONG-TERM RESULTS, HAZARDS AND FAILURES IN COSMETIC SURGERY].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Dermatologic Agents; Drug Hypersensitivity; Drug | 1964 |
[PROBLEMS OF ESTHETIC MEDICINE IN MEDICAL COSMETICS].
Topics: Cicatrix; Cosmetics; Esthetics; Humans; Keloid; Plastics; Surgery, Plastic; Surgical Procedures, Ope | 1964 |
TREATMENT OF KELOIDS WITH TRIAMCINOLONE ACETONIDE INJECTED INTRALESIONALLY.
Topics: Burns; Child; Drug Therapy; Humans; Keloid; Neck; Triamcinolone Acetonide | 1965 |
PRELIMINARY INVESTIGATION OF THE ACTION OF THQ, EDTA AND ESTROGEN ON THE MUCOPOLYSACCHARIDES OF SPONGE IMPLANT CONNECTIVE TISSUE.
Topics: Animals; Connective Tissue; Edetic Acid; Estrogens; Estrone; Glycosaminoglycans; Granulation Tissue; | 1965 |
PROPHYLAXIS AGAINST POSTSURGICAL KELOIDS: RESULTS IN 500 PATIENTS.
Topics: Dexamethasone; Drug Therapy; Humans; Keloid; Lidocaine; Postoperative Complications | 1965 |
[KELOIDS AND THEIR TREATMENT].
Topics: Burns; Burns, Chemical; Cicatrix; Cold Temperature; Cryosurgery; Cryotherapy; Dexamethasone; Fluocin | 1965 |
[SURGICAL TREATMENT OF KELOIDS. SURGERY-RADIOTHERAPY COMBINATION OR "SHAVING OFF"].
Topics: Humans; Keloid; Neoplasms; Radiosurgery; Surgical Procedures, Operative | 1965 |
[PRIMARY BLASTOMATOUS RETICULOSIS OF THE SKIN SIMULATING MORPHEA)].
Topics: Humans; Keloid; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma; Scalp; S | 1965 |
[THE KELOID].
Topics: Cortisone; Humans; Keloid; Radiotherapy | 1965 |
[RADIOTHERAPY OF NON-AUTHENTIC TUMORS OF THE ECTODERM AND MESODERM].
Topics: Cicatrix; Ectoderm; Geriatrics; Humans; Keloid; Male; Mesoderm; Neoplasms; Penile Induration; Radiot | 1964 |
[TREATMENT OF KELOIDS].
Topics: Humans; Keloid; Radiotherapy; Surgical Procedures, Operative | 1964 |
[EXPERIENCES IN THE MEDICAL TREATMENT OF A-BOMB BLAST WOUNDS].
Topics: Bombs; Japan; Keloid; Leukocytes; Nuclear Warfare; Radiation Injuries | 1965 |
[XANTHOFIBROGRANULOMA].
Topics: Granuloma; Humans; Keloid; Retroperitoneal Neoplasms | 1965 |
Spontaneous keloid with unusual histologic features.
Topics: Fibroma; Humans; Keloid; Skin Neoplasms | 1955 |
Control of keloid growth with ultrasonic energy; a report of two cases.
Topics: Biological Phenomena; Fibroma; Humans; Keloid; Physiological Phenomena; Ultrasonic Therapy; Ultrason | 1955 |
[Keloids and their treatment].
Topics: Fibroma; Keloid | 1954 |
[Keloid development in skin transplantation according to the Reverdin method].
Topics: Humans; Keloid; Skin Transplantation | 1959 |
[On Gate's method on the treatment and prevention of keloids].
Topics: Humans; Keloid | 1960 |
Postoperative intestinal obstruction in a patient with keloid scars.
Topics: Cicatrix; Humans; Intestinal Obstruction; Keloid; Medical Records; Postoperative Complications; Tiss | 1961 |
Histogenesis of experimentally produced keloids.
Topics: Keloid | 1962 |
[Physiotherapy. V. Physiotherapy of cicatrices, keloids and dermohypodermic scleroses].
Topics: Cicatrix; Humans; Keloid; Physical Therapy Modalities; Sclerosis; Skin Diseases | 1962 |
Studies on X-agent. XII. Striped patterns produced in kaolin suspensions.
Topics: Humans; Kaolin; Keloid; Radiation; Suspensions | 1961 |
Congenital defects of scalp with keloid formation. Cousins show similar defects.
Topics: Humans; Keloid; Scalp | 1962 |
[Pathogenesis, clinical picture and therapy of keloids].
Topics: Humans; Keloid | 1961 |
[An interesting case showing remarkable preventing effect of radiation on the postoperative keloid formation].
Topics: Humans; Keloid; Postoperative Period; Radiation | 1961 |
[Keloids in the acromial region following BCG vaccination].
Topics: BCG Vaccine; Humans; Keloid; Mycobacterium bovis; Neoplasms; Scapula; Vaccination | 1962 |
[Xanthoma of the mediastinum].
Topics: Humans; Keloid; Mediastinal Neoplasms; Mediastinum; Medical Records; Xanthomatosis | 1962 |
[An experimental study on the effects of wild type p16 gene on the proliferation and metabolism of human keloid fibroblasts].
Topics: Cell Proliferation; Cells, Cultured; DNA; Fibroblasts; Genes, p16; Genetic Therapy; Humans; Keloid; | 2003 |
Vascularization pattern in hypertrophic scars and keloids: a stereological analysis.
Topics: Actins; Adolescent; Adult; Antigens, CD34; Biomarkers; Child; Child, Preschool; Cicatrix, Hypertroph | 2003 |
Treatment of an earlobe keloid.
Topics: Ear, External; Electrosurgery; Evidence-Based Medicine; Humans; Keloid; United States | 2003 |
[Apoptosis of keloid-derived fibroblasts induced by Fas gene transfection].
Topics: Apoptosis; fas Receptor; Fibroblasts; Flow Cytometry; Humans; Keloid; Transfection | 2003 |
A curious keloid of the penis.
Topics: Adult; Anti-Inflammatory Agents; Condylomata Acuminata; Electrocoagulation; Fluocinolone Acetonide; | 2003 |
Verapamil inhibits interleukin-6 and vascular endothelial growth factor production in primary cultures of keloid fibroblasts.
Topics: Analysis of Variance; Apoptosis; Calcium Channel Blockers; Cell Division; Cells, Cultured; Fibroblas | 2003 |
Painless steroid injections for hypertrophic scars and keloids.
Topics: Anesthesia, Local; Anesthetics, Local; Cicatrix, Hypertrophic; Cryosurgery; Humans; Injections, Intr | 2003 |
Topical application of imiquimod 5% cream to keloids alters expression genes associated with apoptosis.
Topics: Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Apoptosis; Arabidopsis Proteins; C | 2003 |
[Investigation of p53 gene mutations in keloids using PCR-SSCP].
Topics: Apoptosis; Base Sequence; Exons; Fibroblasts; Genes, p53; Humans; Keloid; Mutation; Polymerase Chain | 2003 |
Quercetin inhibits fibronectin production by keloid-derived fibroblasts. Implication for the treatment of excessive scars.
Topics: Antioxidants; Blotting, Western; Dermatologic Agents; Fibroblasts; Fibronectins; Humans; Keloid; Mic | 2003 |
Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts.
Topics: Extracellular Matrix; Fibroblasts; Gene Expression; Homeostasis; Humans; Keloid; MAP Kinase Signalin | 2004 |
Silicone gel sheets relieve pain and pruritus with clinical improvement of keloid: possible target of mast cells.
Topics: Administration, Topical; Adult; Aged; Biopsy, Needle; Female; Humans; Immunohistochemistry; Keloid; | 2003 |
[Expression of connective tissue growth factor gene in the hypertrophic scar and keloid tissue].
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Connective Tissue Growth Factor; Female; Gene Expression; | 2003 |
[High expression of macrophage migration inhibitory factor and its role in cellular proliferation and extracellular matrix production in keloid fibroblasts].
Topics: Blotting, Northern; Cell Division; Cells, Cultured; Extracellular Matrix; Fibroblasts; Humans; Immun | 2003 |
Keratinocytes promote proliferation and inhibit apoptosis of the underlying fibroblasts: an important role in the pathogenesis of keloid.
Topics: Adolescent; Adult; Apoptosis; Cell Communication; Cell Division; Cells, Cultured; Child; Coculture T | 2003 |
Expression of urokinase-type plasminogen activator and its receptor in keloids.
Topics: Cell Movement; Cicatrix; Confounding Factors, Epidemiologic; Extracellular Matrix; Humans; Immunohis | 2003 |
Acute IgA nephropathy following keloid scar formation due to burn injury.
Topics: Acute Disease; Burns; Child; Diagnosis, Differential; Glomerulonephritis, IGA; Humans; Keloid; Male | 2003 |
Cryotherapy modifies synthetic activity and differentiation of keloidal fibroblasts in vitro.
Topics: Adolescent; Adult; Cell Differentiation; Cell Division; Cells, Cultured; Collagen Type I; Collagen T | 2003 |
Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts.
Topics: Adult; Cell Hypoxia; Cells, Cultured; Cycloheximide; Dactinomycin; Deferoxamine; Female; Fibroblasts | 2003 |
Effect of blended CO2 and erbium:YAG laser irradiation on normal and keloid fibroblasts: a serum-free study.
Topics: Cells, Cultured; Culture Media, Serum-Free; Fibroblasts; Humans; Keloid; Laser Therapy | 2003 |
Laser treatment of scars.
Topics: Cicatrix; Humans; Keloid; Laser Therapy | 2004 |
Sphingosine may have cytotoxic effects via apoptosis on the growth of keloid fibroblasts.
Topics: Apoptosis; Biopsy, Needle; Case-Control Studies; Cell Division; Cell Survival; Cells, Cultured; Cera | 2004 |
Keloidal scleroderma.
Topics: Adult; Antirheumatic Agents; Azathioprine; Female; Humans; Keloid; Penicillamine; Scleroderma, Diffu | 2004 |
Tretinoin reverses upregulation of matrix metalloproteinase-13 in human keloid-derived fibroblasts.
Topics: Adult; Collagenases; Culture Media; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Humans; | 2003 |
Carcinoma en cuirasse presenting as keloids of the chest.
Topics: Breast Neoplasms; Carcinoma; Female; Humans; Keloid; Lymphatic Metastasis; Middle Aged; Skin Neoplas | 2004 |
Expression of p53 family in scars.
Topics: Adolescent; Adult; Atrophy; Blotting, Western; Child; Child, Preschool; DNA-Binding Proteins; Genes, | 2004 |
Clinical evaluation of ulnar nerve repair at wrist level.
Topics: Adult; Female; Follow-Up Studies; Humans; Keloid; Male; Neurosurgical Procedures; Postoperative Comp | 2004 |
[Treatment, by Charpy's method, of a case of recent and extensive keloids, following a burn].
Topics: Burns; Cholestanes; Humans; Keloid; Vitamin D; Vitamins | 1950 |
[Failure of preventive irradiation following surgical excision of a keloid].
Topics: Humans; Keloid; X-Ray Therapy | 1950 |
Keloid of conjunctiva.
Topics: Conjunctiva; Keloid | 1951 |
[Keloids and radium].
Topics: Humans; Keloid; Radium | 1951 |
Lymphangioma circumscriptum and keloids.
Topics: Hemangioma; Humans; Keloid; Lymphangioma; Neoplasms | 1951 |
Keloids and skin papilomas.
Topics: Humans; Keloid; Papilloma; Skin | 1951 |
[Results of "functional parathyroidectomy" in keloid therapy].
Topics: Humans; Keloid; Parathyroidectomy | 1951 |
[Cicatricial keloids of the horse].
Topics: Animals; Horses; Keloid | 1951 |
[Therapy of keloids; radium and contact Roentgen therapy].
Topics: Humans; Keloid; Radium | 1951 |
Keloid resulting from a positive patch test.
Topics: Fibroma; Humans; Keloid; Patch Tests | 1952 |
Corticotropin (ACTH) in treatment of keloids.
Topics: Adrenocorticotropic Hormone; Fibroma; Keloid | 1952 |
[The possibility of a pathogenetic interpretation of keloids in relation to adrenal cortex alterations; clinical case report].
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Fibroma; Keloid | 1951 |
Keloid.
Topics: Cortisone; Fibroma; Keloid | 1951 |
[Local treatment of keloid with hyaluronidase].
Topics: Fibroma; Humans; Hyaluronoglucosaminidase; Keloid | 1951 |
[Spontaneous keloid].
Topics: Fibroma; Keloid | 1951 |
[Checkerboard keloid of the donor site after skin grafting].
Topics: Fibroma; Humans; Keloid; Skin; Skin Transplantation; Transplantation; Transplants | 1951 |
Use of vitamin E in the treatment of keloids.
Topics: Fibroma; Keloid; Vitamin E | 1951 |
Keloid and self administration of adrenaline.
Topics: Epinephrine; Fibroma; Humans; Keloid; Self Administration; Self Care | 1951 |
Keloid.
Topics: Cortisone; Fibroma; Humans; Keloid | 1951 |
A study of keloids due to exposure to the atomic bomb in Hiroshima city [Japanese text].
Topics: Fibroma; Humans; Keloid; Nuclear Weapons; Radiation Effects | 1951 |
Some observations on connective tissue growth and tissue culture in relation to keloid formation; a preliminary report.
Topics: Connective Tissue; Humans; Keloid; Tissue Culture Techniques | 1951 |
Keloids and their treatment.
Topics: Fibroma; Keloid | 1952 |
[Pathogenesis of Keloids].
Topics: Fibroma; Humans; Keloid | 1952 |
[Therapy of fresh keloids with hyaluronidase].
Topics: Fibroma; Hyaluronoglucosaminidase; Keloid | 1952 |
Crosstalk of hypoxia-mediated signaling pathways in upregulating plasminogen activator inhibitor-1 expression in keloid fibroblasts.
Topics: Blotting, Northern; Blotting, Western; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Gene Ex | 2004 |
[Scars management].
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Physical Therapy Modalities; Plastic Surgery Procedures; Pos | 2004 |
Flashlamp pulsed dye laser (PDL) suppression of keloid proliferation through down-regulation of TGF-beta1 expression and extracellular matrix expression.
Topics: Adolescent; Adult; Child; Collagen Type III; Down-Regulation; Extracellular Matrix; Female; Fibrobla | 2004 |
Genetic susceptibility to keloid disease: transforming growth factor beta receptor gene polymorphisms are not associated with keloid disease.
Topics: Case-Control Studies; DNA; DNA Primers; Gene Frequency; Genetic Predisposition to Disease; Genotype; | 2004 |
[Unclear connective tissue tumor].
Topics: Aged; Eyelid Diseases; Eyelids; Humans; Keloid; Male | 2004 |
[Gigantic keloïds after chicken-pox. A case report].
Topics: Adult; Chickenpox; Child; Female; Humans; Keloid | 2003 |
[Cutaneous oxygen supply. With special consideration of skin uptake of oxygen from the atmosphere].
Topics: Blood Gas Monitoring, Transcutaneous; Capillary Permeability; Cell Division; Diffusion; Humans; Kelo | 2004 |
Description of site-specific morphology of keloid phenotypes in an Afrocaribbean population.
Topics: Adolescent; Adult; Aged; Black People; Child; Child, Preschool; England; Female; Humans; Jamaica; Ke | 2004 |
[Prevention and treatment of pathological scars].
Topics: Cicatrix; Humans; Keloid; Wound Healing | 2004 |
Keloid formation after syndactyly reconstruction: associated conditions, prevalence, and preliminary report of a treatment method.
Topics: Child, Preschool; Dermatologic Agents; Female; Humans; Infant; Keloid; Male; Methotrexate; Postopera | 2004 |
Hexose sugars differentially alter collagen gene expression and synthesis in fibroblasts derived from granulation tissue, hypertrophic scar and keloid.
Topics: Cells, Cultured; Cicatrix, Hypertrophic; Collagen; Collagen Type I; Collagen Type III; Fibroblasts; | 2004 |
A new skin closure technique with running sutures and tissue adhesive.
Topics: Humans; Keloid; Suture Techniques; Tissue Adhesives | 2004 |
[Postoperative electron beam irradiation therapy for keloid:a follow-up study of 48 patients].
Topics: Adult; Combined Modality Therapy; Electrons; Female; Follow-Up Studies; Humans; Keloid; Male; Postop | 2004 |
[Analysis of curative result for keloid with integrated methods].
Topics: Adolescent; Adult; Beta Particles; Combined Modality Therapy; Dermatologic Surgical Procedures; Dose | 2004 |
Intralesional 5-fluorouracil in the treatment of keloid scars.
Topics: Acne Keloid; Adult; Antimetabolites; Betamethasone; Facial Dermatoses; Female; Fluorouracil; Follow- | 2004 |
Disease dictionary. Keloids.
Topics: Keloid; Terminology as Topic; Therapeutics | 2004 |
Corneal keloid: clinical, ultrasonographic, and ultrastructural characteristics.
Topics: Aged; Cataract; Cataract Extraction; Cornea; Corneal Diseases; Corneal Injuries; Corneal Transplanta | 2004 |
A surgical approach for earlobe keloid: keloid fillet flap.
Topics: Adult; Ear, External; Female; Humans; Keloid; Male; Middle Aged; Plastic Surgery Procedures; Punctur | 2004 |
[Evaluation of radiation therapy for keloid using electron beam].
Topics: Electrons; Keloid; Models, Theoretical; Radiotherapy Dosage | 2004 |
Reduced dermatopontin expression is a molecular link between uterine leiomyomas and keloids.
Topics: Adult; Carrier Proteins; Cell Adhesion Molecules; Chondroitin Sulfate Proteoglycans; Extracellular M | 2004 |
Genome scans provide evidence for keloid susceptibility loci on chromosomes 2q23 and 7p11.
Topics: Black or African American; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 7; Family Health; Fe | 2004 |
Genome scans provide evidence for keloid susceptibility loci on chromosomes 2q23 and 7p11.
Topics: Black or African American; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 7; Family Health; Fe | 2004 |
Genome scans provide evidence for keloid susceptibility loci on chromosomes 2q23 and 7p11.
Topics: Black or African American; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 7; Family Health; Fe | 2004 |
Genome scans provide evidence for keloid susceptibility loci on chromosomes 2q23 and 7p11.
Topics: Black or African American; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 7; Family Health; Fe | 2004 |
[High efficient generation of recombinant adenovirus containing human Fas gene using a method of homologous recombination in bacteria].
Topics: Adenoviridae; Animals; Bacteria; Blotting, Western; Cell Line; Cells, Cultured; DNA, Recombinant; fa | 2004 |
Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor.
Topics: Epidermis; Humans; In Situ Hybridization; Keloid; Neovascularization, Pathologic; Vascular Endotheli | 2004 |
Treatment of earlobe keloids using the cobalt 60 teletherapy unit.
Topics: Cobalt Radioisotopes; Ear, External; Female; Humans; Keloid; Male; Radioisotope Teletherapy; Treatme | 2004 |
Keloid scars are formed by polyclonal fibroblasts.
Topics: Female; Fibroblasts; Humans; Keloid; Polymerase Chain Reaction | 2004 |
Cushing's syndrome after intra-articular and intradermal administration of triamcinolone acetonide in three pediatric patients.
Topics: Adolescent; Anti-Inflammatory Agents; Arthritis, Juvenile; Child; Cushing Syndrome; Female; Glucocor | 2004 |
[Excimer laser. Treatment of iatrogenic hypopigmentation following skin resurfacing].
Topics: Aged; Cosmetic Techniques; Female; Follow-Up Studies; Humans; Hypopigmentation; Iatrogenic Disease; | 2004 |
Scars and keloids.
Topics: Cicatrix; Humans; Keloid; Suture Techniques; Wound Healing | 2004 |
[Treatment of helical keloid with retroauricular skin expansion].
Topics: Adolescent; Adult; Child; Ear; Female; Humans; Keloid; Male; Surgery, Plastic; Treatment Outcome | 2003 |
Scar endometriosis developing after an umbilical hernia repair with mesh.
Topics: Adult; Endometriosis; Female; Foreign-Body Reaction; Hernia, Umbilical; Humans; Keloid; Laparoscopy; | 2004 |
Painless steroid injections for hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Humans; Injections, Intralesional; Keloid; Pain; Steroids; Therapy, Computer | 2004 |
Development of gene microarray in screening differently expressed genes in keloid and normal-control skin.
Topics: DNA, Complementary; Humans; Keloid; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reacti | 2004 |
Retrospective analysis of treatment of unresectable keloids with primary radiation over 25 years.
Topics: Adolescent; Adult; Humans; Keloid; Male; Manitoba; Medical Records; Middle Aged; Radiation Dosage; R | 2004 |
Prevention and treatment of keloids with intralesional verapamil.
Topics: Adolescent; Adult; Female; Humans; Injections, Intralesional; Keloid; Male; Treatment Outcome; Verap | 2004 |
Molecular characterization and expression of p63 isoforms in human keloids.
Topics: DNA-Binding Proteins; Genes, Tumor Suppressor; Humans; Immunohistochemistry; Keloid; Phosphoproteins | 2004 |
Activation of NFkappaB signal pathways in keloid fibroblasts.
Topics: Adolescent; Adult; Blotting, Western; Dermis; Fibroblasts; Humans; Keloid; Male; NF-kappa B; Oligonu | 2004 |
Increased formation of pyridinoline cross-links due to higher telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon.
Topics: Amino Acids; Cells, Cultured; Cicatrix, Hypertrophic; Dupuytren Contracture; Fascia; Fibrosis; Hand; | 2004 |
General and plastic surgery devices; classification of silicone sheeting. Final rule.
Topics: Bandages; Cicatrix, Hypertrophic; Equipment Safety; Humans; Keloid; Product Labeling; Silicones; Sur | 2004 |
PKC412 induces apoptosis through a caspase-dependent mechanism in human keloid-derived fibroblasts.
Topics: Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Enzyme Inhibitors; Female; Fibr | 2004 |
The wound healing process: part III--the finale.
Topics: Apoptosis; Cell Division; Cicatrix; Cicatrix, Hypertrophic; Collagen; Fibroblasts; Humans; Keloid; W | 2004 |
[Study on the management of postburn pathological scars].
Topics: Burns; Cicatrix, Hypertrophic; Humans; Keloid | 2004 |
[Effects of antisense oligonucleotides on the expression of connective tissue growth factor gene and on the collagen synthesis in the cultured human keloid fibroblasts].
Topics: Collagen; Connective Tissue Growth Factor; Fibroblasts; Humans; Immediate-Early Proteins; Intercellu | 2004 |
[Study on the expression of tenascin-C in keloid and hyperplastic scar].
Topics: Cicatrix, Hypertrophic; Female; Humans; Immunohistochemistry; Keloid; Male; Skin; Tenascin | 2004 |
[Experimental study on p53 gene mutation in keloid fibroblasts].
Topics: Female; Fibroblasts; Genes, p53; Humans; Keloid; Male; Mutation | 2004 |
Phosphorylation of extracellular signal-regulated protein kinase in cultured keloid fibroblasts when stimulated by platelet-derived growth factor BB.
Topics: Adolescent; Adult; Becaplermin; Blotting, Western; Cells, Cultured; Extracellular Signal-Regulated M | 2003 |
[Relationship of overexpression of angiogenesis factors and their receptors with invasive growth of keloid].
Topics: Adolescent; Adult; Aged; Angiogenesis Inducing Agents; Child; Child, Preschool; Female; Fibroblast G | 2004 |
[A study of the abnormalities of human epiderm in keloids and hypertrophic scars].
Topics: Cicatrix, Hypertrophic; Epidermis; Female; Humans; Hyperplasia; Immunohistochemistry; In Situ Hybrid | 2004 |
Histopathological differential diagnosis of keloid and hypertrophic scar.
Topics: Actins; Adult; Aged; Cicatrix, Hypertrophic; Diagnosis, Differential; Humans; Keloid; Middle Aged; M | 2004 |
[Hypertrophic and cheloid cicatrices; important factor on its cause and treatment].
Topics: Cicatrix; Humans; Hypertrophy; Keloid | 1949 |
Multiple cheloids.
Topics: Keloid | 1949 |
Liquid nitrogen in the treatment of skin diseases.
Topics: Cicatrix; Dermatitis, Contact; Freezing; Hemangioma; Humans; Keloid; Keratosis; Leukoplakia; Nitroge | 1950 |
Keloid associated with acne in a young girl.
Topics: Acne Vulgaris; Female; Humans; Keloid | 1950 |
A study of keloids and related conditions.
Topics: Humans; Keloid | 1950 |
Primary skin grafting in ear lobule keloid.
Topics: Adolescent; Adult; Ear, External; Esthetics; Female; Follow-Up Studies; Humans; Keloid; Middle Aged; | 2004 |
A U-loop pressure clip for earlobe keloid.
Topics: Ear, External; Equipment Design; Humans; Keloid; Pressure | 2004 |
Inadequate blood supply persists in keloids.
Topics: Adenosine Triphosphate; Biopsy, Needle; Cicatrix, Hypertrophic; Female; Humans; Hypoxia; Immunohisto | 2004 |
Spontaneous keloids in siblings.
Topics: Adult; Female; Humans; Keloid; Siblings; Steroids | 2004 |
Adjuvant high dose rate brachytherapy (Ir-192) in the management of keloids which have recurred after surgical excision and external radiation.
Topics: Adolescent; Adult; Brachytherapy; Cohort Studies; Combined Modality Therapy; Female; Follow-Up Studi | 2004 |
Autoantibodies to a collagen-specific molecular chaperone, heat-shock protein 47, in systemic sclerosis.
Topics: Adolescent; Adult; Aged; Animals; Autoantibodies; Child; Dermatomyositis; Female; Heat-Shock Protein | 2004 |
[Experimental study on apoptosis of keloid-derived fibroblast transducted with Fas gene by recombinant adenovirus].
Topics: Adenoviridae; Apoptosis; DNA, Recombinant; fas Receptor; Fibroblasts; Flow Cytometry; Genetic Vector | 2004 |
[Expression and significance of alpha5beta1 integrin in abnormal scars].
Topics: Cicatrix; Humans; Immunohistochemistry; Integrin alpha5beta1; Keloid; Microscopy, Immunoelectron; Sk | 2004 |
Suppression of transforming growth factor beta/smad signaling in keloid-derived fibroblasts by quercetin: implications for the treatment of excessive scars.
Topics: Antioxidants; Blotting, Western; Cell Proliferation; Cells, Cultured; Cicatrix; DNA-Binding Proteins | 2004 |
Pruritus, pain, and small nerve fiber function in keloids: a controlled study.
Topics: Adult; Female; Humans; Keloid; Male; Middle Aged; Nerve Fibers; Pain; Pain Threshold; Pruritus; Sens | 2004 |
Upregulation of the NNP-1 (novel nuclear protein-1, D21S2056E) gene in keloid tissue determined by cDNA microarray and in situ hybridization.
Topics: Adolescent; Adult; DNA, Complementary; Female; Humans; In Situ Hybridization; Keloid; Male; Nuclear | 2004 |
A transcriptional factor decoy against AP-1 suppresses TGF-beta1-induced type I collagen gene expression in cultured keloid fibroblasts.
Topics: Adult; Cells, Cultured; Collagen Type I; Fibroblasts; Genetic Therapy; Humans; Keloid; Oligodeoxyrib | 2005 |
Keloid disease: clinical relevance of single versus multiple site scars.
Topics: Adolescent; Adult; Age Factors; Age of Onset; Aged; Aged, 80 and over; Child; Child, Preschool; Fami | 2005 |
Suppressed TGF-beta1 expression is correlated with up-regulation of matrix metalloproteinase-13 in keloid regression after flashlamp pulsed-dye laser treatment.
Topics: Adolescent; Adult; Child; Collagenases; Down-Regulation; Female; Humans; Keloid; Laser Therapy; Male | 2005 |
Activation of ERK and p38 kinase mediated keloid fibroblast apoptosis after flashlamp pulsed-dye laser treatment.
Topics: Adolescent; Adult; Apoptosis; Caspase 3; Caspases; Cell Proliferation; Child; Enzyme Activation; Ext | 2005 |
Keloid development within adolescent striae distensae.
Topics: Adolescent; Adult; Cicatrix; Connective Tissue Diseases; Humans; Keloid; Male | 2005 |
[Expression of thymosin beta 4 mRNA expression in keloid tissues and fibroblasts cultured from keloid and its significance].
Topics: Cells, Cultured; Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid; RNA, Messenger; Thymosin | 2005 |
[Relationship between keloid proliferation and apoptosis of epithelial cell with destruction of structure and function of skin appendages].
Topics: Adolescent; Adult; Apoptosis; Cell Proliferation; Child, Preschool; Epithelial Cells; Female; Humans | 2005 |
[The research of assembling animal models of keloid employing the method of tissue engineering].
Topics: Adult; Animals; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Humans; Keloid; Lactic | 2005 |
[p53 gene codon 72 polymorphism and susceptibility to keloid in Chinese population].
Topics: Alleles; Arginine; Asian People; China; Codon; Exons; Gene Frequency; Genetic Predisposition to Dise | 2005 |
[Experimental gene therapy of keloid in vitro using recombinant adenovirus coding for Fas gene].
Topics: Adenoviridae; Apoptosis; Cell Line; Cell Proliferation; fas Receptor; Fibroblasts; Genetic Therapy; | 2005 |
[Study of the expression of heat shock protein 47 and its correlation to collagen].
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix, Hypertrophic; Collagen; HSP47 Heat-Shock Prote | 2005 |
[The role of myofibroblast in the development of pathological scar].
Topics: Actins; Adolescent; Adult; Child; Child, Preschool; Cicatrix, Hypertrophic; Fibroblasts; Humans; Imm | 2005 |
Intralesional 5-fluorouracil in the treatment of keloids: an open clinical and histopathologic study.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Child; Female; Fluorouracil; Humans; Injec | 2005 |
Correction of the lobule.
Topics: Dermatologic Surgical Procedures; Ear Cartilage; Ear, External; Esthetics; Follow-Up Studies; Humans | 2004 |
Etk/Bmx mediates expression of stress-induced adaptive genes VEGF, PAI-1, and iNOS via multiple signaling cascades in different cell systems.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Line; Enzyme Activation; Enzyme Inhibitors; Gen | 2005 |
[An inflammation reaction in the postvaccinal keloid scar].
Topics: Adjuvants, Immunologic; Adolescent; BCG Vaccine; Female; Humans; Inflammation; Keloid; Tuberculosis | 2005 |
Use of mitomycin C for treatment of keloid: a preliminary report.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; F | 2005 |
Hypertrophic and keloidal scars: an approach to polytherapy.
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Cryotherapy; Female; Glucocort | 2005 |
Global gene expression analysis of keloid fibroblasts in response to electron beam irradiation reveals the involvement of interleukin-6 pathway.
Topics: Adult; Cells, Cultured; Collagen; Electrons; Extracellular Matrix Proteins; Female; Fibroblasts; Gen | 2005 |
Lessons in giving vaccines: soft tissue complications of vaccinations.
Topics: Adjuvants, Pharmaceutic; Aluminum Hydroxide; Anti-Bacterial Agents; Drug Hypersensitivity; Granuloma | 2005 |
[Effects of connective tissue growth factor antisense oligonucleotides on the cultured human keloid fibroblasts in vitro].
Topics: Apoptosis; Cell Differentiation; Cells, Cultured; Connective Tissue Growth Factor; Fibroblasts; Huma | 2004 |
The efficacy of magnetic disks for the treatment of earlobe hypertrophic scar.
Topics: Adolescent; Adult; Body Piercing; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Humans; | 2005 |
Conditioned medium from keloid keratinocyte/keloid fibroblast coculture induces contraction of fibroblast-populated collagen lattices.
Topics: Actins; Antibodies; Cells, Cultured; Coculture Techniques; Collagen; Culture Media, Conditioned; Epi | 2005 |
[Chromosomal aberration in human keloid analyzed by comparative genomic hybridization].
Topics: Adult; Chromosome Aberrations; Chromosomes, Human, Pair 1; Comparative Genomic Hybridization; DNA Pr | 2005 |
[Investigation of p53 polymorphism for genetic predisposition of keloid and hypertrophic scar].
Topics: Cicatrix, Hypertrophic; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; | 2005 |
[The expression of tenascin-C mRNA in keloids and hypertrophic scars].
Topics: Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; RNA, Messenger; Tenascin | 2005 |
Relationship between age of ear piercing and keloid formation.
Topics: Adolescent; Age Factors; Body Piercing; Child; Child, Preschool; Ear, External; Female; Humans; Infa | 2005 |
Treatment of scattered glass foreign bodies in both the superficial and deep neck: a case report.
Topics: Accidents, Traffic; Adolescent; Edema; Face; Foreign Bodies; Glass; Humans; Keloid; Magnetic Resonan | 2005 |
Consent to medical treatment.
Topics: Adult; Family Practice; Female; Humans; Informed Consent; Keloid; Nevus; Patient Participation; Pati | 2005 |
An increase of MMP-1 is stimulated by sphingosine in keloid fibroblasts.
Topics: Cells, Cultured; Ceramides; Fibroblasts; Humans; Keloid; Matrix Metalloproteinase 1; Sphingosine | 2005 |
Interesting case: An unusual case of keloid scarring.
Topics: Adult; Diagnosis, Differential; Head and Neck Neoplasms; Humans; Keloid; Male; Neck | 2006 |
SB-431542 inhibits TGF-beta-induced contraction of collagen gel by normal and keloid fibroblasts.
Topics: Actins; Benzamides; Collagen; Dioxoles; Fibroblasts; Gels; Humans; Keloid; Transforming Growth Facto | 2005 |
Keloid secondary to therapeutic cupping: an unusual complication.
Topics: Adult; Back; Cough; Diagnosis, Differential; Female; Humans; Keloid; Physical Therapy Modalities | 2005 |
The keloid fillet flap.
Topics: Ear, External; Humans; Keloid; Plastic Surgery Procedures; Surgical Flaps | 2005 |
A case of congenital corneal keloid.
Topics: Adult; Corneal Diseases; Humans; Keloid; Keratoplasty, Penetrating; Male | 2005 |
Comparative study of keloid formation in humans and laboratory animals.
Topics: Adolescent; Animals; Cells, Cultured; Child; Female; Fibroblasts; Humans; Keloid; Male; Mice; Mice, | 2005 |
Tubal occlusion causing infertility due to an excessive inflammatory response in patients with predisposition for keloid formation.
Topics: Chlamydia Infections; Cytokines; Disease Susceptibility; Fallopian Tube Diseases; Female; Humans; In | 2005 |
[Construction of animal models of keloid by tissue engineering].
Topics: Animals; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Humans; Keloid; Mice; Mice, I | 2005 |
Studies of transforming growth factors beta 1-3 and their receptors I and II in fibroblast of keloids and hypertrophic scars.
Topics: Case-Control Studies; Cicatrix, Hypertrophic; DNA Primers; Fibroblasts; Humans; Immunohistochemistry | 2005 |
Genetic susceptibility to keloid disease: mutation screening of the TGFbeta3 gene.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; DNA Mutational Analysis; Exons; Female; Gen | 2005 |
[Relationship between angiogenesis and expression of HO-1 of scar].
Topics: Adult; Cicatrix; Cicatrix, Hypertrophic; Female; Heme Oxygenase-1; Humans; Keloid; Male; Middle Aged | 2005 |
Smad3 signalling plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions.
Topics: Adolescent; Adult; Benzamides; Burns; Cell Division; Child; Cicatrix; Coculture Techniques; Collagen | 2005 |
Intralesional excision of keloids.
Topics: Apoptosis; Ear, External; Fibroblasts; Humans; Keloid; Plastic Surgery Procedures; Recurrence; Surgi | 2005 |
Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration.
Topics: Cell Movement; Cells, Cultured; Collagen Type I; Culture Media, Conditioned; Female; Fibroblasts; Gr | 2005 |
Photodynamic therapy on keloid fibroblasts in tissue-engineered keratinocyte-fibroblast co-culture.
Topics: Adult; Cell Death; Cell Survival; Cells, Cultured; Coculture Techniques; Collagen; Dose-Response Rel | 2005 |
[p53 gene codon 72 polymorphism and susceptibility to keloid].
Topics: Adolescent; Adult; Alleles; Asian People; Base Sequence; Child; China; Codon; Female; Gene Frequency | 2005 |
[Detection of expression of heat shock protein 47 mRNA in pathological scar tissue by using real-time fluorescent quantitative RT-PCR].
Topics: Adolescent; Adult; Child; Cicatrix, Hypertrophic; Gene Expression Profiling; HSP47 Heat-Shock Protei | 2005 |
Increased transcriptional response to mechanical strain in keloid fibroblasts due to increased focal adhesion complex formation.
Topics: Adolescent; Adult; Aged; Child; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Foc | 2006 |
[Construction of recombinant human smad 7 adenoviral vector and its expression in vitro].
Topics: Adenoviridae; Cells, Cultured; Fibroblasts; Genetic Vectors; Humans; Keloid; Recombinant Fusion Prot | 2005 |
Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity.
Topics: Adolescent; Adult; Animals; Antibodies; Blotting, Northern; Cells, Cultured; Endothelium, Vascular; | 2005 |
Keloids in dermatology outpatients in Lomé, Togo.
Topics: Acne Keloid; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Humans; Ke | 2005 |
Hypertrophic scar fibroblasts have increased connective tissue growth factor expression after transforming growth factor-beta stimulation.
Topics: Adult; Cells, Cultured; Child; Cicatrix, Hypertrophic; Connective Tissue Growth Factor; Female; Fibr | 2005 |
Gene expression in human keloids is altered from dermal to chondrocytic and osteogenic lineage.
Topics: Adolescent; Adult; Aged; Basic Helix-Loop-Helix Transcription Factors; Cartilage; Cell Lineage; Chon | 2005 |
[Interaction between macrophage migration inhibitory factor and lysophosphatidic acid in formation of keloid tissue]].
Topics: Cell Movement; Cells, Cultured; Fibroblasts; Humans; Keloid; Lysophospholipids; Macrophage Migration | 2005 |
Cutaneous cysts of the head and neck.
Topics: Adult; Dermoid Cyst; Epidermal Cyst; Female; Head and Neck Neoplasms; Hidrocystoma; Humans; Keloid; | 2005 |
[Pathological genomics of keloid fibroblastic cells].
Topics: Adult; Cells, Cultured; Female; Fibroblasts; Gene Expression; Gene Expression Profiling; Genomics; H | 2005 |
Results of postoperative (90)Sr radiotherapy of keloids in view of patients' subjective assessment.
Topics: Adolescent; Adult; Aged; Brachytherapy; Child; Female; Humans; Keloid; Male; Middle Aged; Patient Sa | 2005 |
Defective induction of senescence during wound healing is a possible mechanism of keloid formation.
Topics: Amphotericin B; Apoptosis; Cell Proliferation; Cellular Senescence; Extracellular Matrix; Fibroblast | 2006 |
Hypoxia-induced HIF-1 alpha accumulation is augmented in a co-culture of keloid fibroblasts and human mast cells: involvement of ERK1/2 and PI-3K/Akt.
Topics: Cell Communication; Cell Hypoxia; Cells, Cultured; Coculture Techniques; Extracellular Signal-Regula | 2006 |
Keloids are not angiogenic lesions.
Topics: Humans; Keloid; Neovascularization, Pathologic; Vascular Endothelial Growth Factor A | 2005 |
Hypertrophic response and keloid diathesis: two very different forms of scar.
Topics: Apoptosis; Cicatrix, Hypertrophic; Extracellular Matrix; Fibroblasts; Humans; Immunohistochemistry; | 2005 |
Bilateral corneal scarring after LASIK and PRK in a patient with propensity to keloid scar formation.
Topics: Adult; Cicatrix; Corneal Diseases; Disease Susceptibility; Humans; Keloid; Keratomileusis, Laser In | 2007 |
[Nerve regeneration of hypertrophic scars and keloids after deep burns].
Topics: Adolescent; Adult; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Humans; Infant; K | 2005 |
Cryosurgery in the treatment of earlobe keloids: report of seven cases.
Topics: Adolescent; Adult; Body Piercing; Child; Cryosurgery; Ear, External; Female; Humans; Keloid; Male; P | 2005 |
Keloid formation on an inconspicuous penis.
Topics: Adolescent; Circumcision, Male; Humans; Keloid; Male; Penile Diseases; Penis | 2005 |
Up-regulation of metallothionein isoforms in keloid keratinocytes.
Topics: Cells, Cultured; Humans; Keloid; Keratinocytes; Metallothionein; Microscopy, Electron, Transmission; | 2006 |
A 1.8-kg keloid of the arm.
Topics: Adolescent; BCG Vaccine; Female; Humans; Keloid; Radiotherapy Dosage; Vaccination | 2006 |
Anaphylactic reaction to intralesional steroid injection.
Topics: Adult; Anaphylaxis; Glucocorticoids; Humans; Keloid; Male; Triamcinolone Acetonide | 2006 |
Postsurgical use of imiquimod 5% cream in the prevention of earlobe keloid recurrences: results of an open-label, pilot study.
Topics: Adolescent; Adult; Aminoquinolines; Antineoplastic Agents; Ear Diseases; Ear, External; Female; Huma | 2005 |
Cutaneous tissue angiotensin-converting enzyme may participate in pathologic scar formation in human skin.
Topics: Adolescent; Adult; Aged; Child; Cicatrix, Hypertrophic; Female; Fibroblasts; Humans; Immunohistochem | 2006 |
[Just for fashion].
Topics: Adrenal Cortex Hormones; Body Piercing; Combined Modality Therapy; Female; Follow-Up Studies; Humans | 2005 |
[Expression and significance of Skp2 and p27kip1 protein in pathological scar].
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix, Hypertrophic; Cyclin-Dependent Kinase Inhibito | 2005 |
P38 MAP kinase mediates transforming growth factor-beta2 transcription in human keloid fibroblasts.
Topics: Cells, Cultured; Fibroblasts; Humans; Keloid; p38 Mitogen-Activated Protein Kinases; Serum; Signal T | 2006 |
Keloid epidemiology: population based studies needed.
Topics: Female; Genetic Predisposition to Disease; Humans; Keloid; Patient Acceptance of Health Care | 2006 |
Keloid-derived fibroblasts have a diminished capacity to produce prostaglandin E2.
Topics: Adult; Aged; Analysis of Variance; Biopsy, Needle; Cell Proliferation; Dinoprostone; Enzyme-Linked I | 2006 |
[Establishment of immortalized lymphoblastoid cell bank of a keloid pedigree].
Topics: Adolescent; Adult; Aged; Cell Line, Transformed; Cell Transformation, Viral; Child; Child, Preschool | 2006 |
Upregulation of TGF-beta1 expression may be necessary but is not sufficient for excessive scarring.
Topics: Actins; Animals; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Fibroblasts; Humans; K | 2006 |
Nitric oxide produced by iNOS is associated with collagen synthesis in keloid scar formation.
Topics: Cells, Cultured; Cicatrix; Collagen; Collagen Type I; Dose-Response Relationship, Drug; Fibroblasts; | 2006 |
Decreased prostaglandin E2 production by inflammatory cytokine and lower expression of EP2 receptor result in increased collagen synthesis in keloid fibroblasts.
Topics: Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Human | 2006 |
Assessment of morphological and immunohistological alterations in long-term keloid skin explants.
Topics: Cell Differentiation; Collagen; Collagen Type I; Humans; Immunohistochemistry; Keloid; Organ Culture | 2005 |
Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients.
Topics: Adolescent; Adult; Aged; Asian People; Child; Child, Preschool; Cicatrix; Female; Glucocorticoids; H | 2006 |
[Differential gene expression profile of keloids: a study with cDNA microarray].
Topics: Connective Tissue Growth Factor; Gene Expression Profiling; Humans; Immediate-Early Proteins; Interc | 2006 |
New technique for injecting corticosteroid in keloids scarring.
Topics: Adrenal Cortex Hormones; Equipment Design; Humans; Injections, Subcutaneous; Keloid; Surgery, Plasti | 2006 |
Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation.
Topics: Adolescent; Adult; Anthracenes; Blood Proteins; Culture Media, Conditioned; Enzyme Inhibitors; Extra | 2006 |
[Study on poly A site gene mutation of transforming growth factor-beta1 receptor type II between multiple and single site keloid].
Topics: Adolescent; Adult; Base Sequence; Child; Child, Preschool; Female; Genetic Vectors; Humans; Keloid; | 2006 |
Dexamethasone induction of keloid regression through effective suppression of VEGF expression and keloid fibroblast proliferation.
Topics: Antibodies, Monoclonal; Cell Proliferation; Cells, Cultured; Dexamethasone; Endothelial Cells; Fibro | 2006 |
Combined therapy in the treatment of auricular keloids.
Topics: Adolescent; Adult; Body Piercing; Combined Modality Therapy; Ear Diseases; Ear, External; Female; Gl | 2006 |
Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration.
Topics: Base Sequence; Cell Division; Cell Movement; Collagen; DNA Primers; Humans; Keloid; Molecular Sequen | 2006 |
Squamous cell carcinoma of the auricle arising from keloid after radium needle therapy.
Topics: Aged, 80 and over; Brachytherapy; Carcinoma, Squamous Cell; Ear Neoplasms; Ear, External; Humans; Ke | 2006 |
Elevated prolidase activity in keloids: correlation with type I collagen turnover.
Topics: Adolescent; Adult; Cells; Cells, Cultured; Collagen; Collagen Type I; Culture Media, Conditioned; Di | 2006 |
Experience with keloids after excision and application of 5% imiquimod cream.
Topics: Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Drug Administration Schedule; Ear | 2006 |
Topical interferon-alpha2b and keloid treatment: a place for pretreatment?
Topics: Adjuvants, Immunologic; Administration, Topical; Adult; Aminoquinolines; Combined Modality Therapy; | 2006 |
Decreased expression of inhibitory SMAD6 and SMAD7 in keloid scarring.
Topics: Blotting, Western; Cells, Cultured; Fibroblasts; Humans; Keloid; Reverse Transcriptase Polymerase Ch | 2006 |
Unraveling the basic principles.
Topics: Animals; Colon; Humans; Intestinal Mucosa; Keloid; Kidney; Muscle, Skeletal; Regeneration | 2006 |
Postoperative radiotherapy with high dose rate iridium 192 mould for prevention of earlobe keloids.
Topics: Adolescent; Adult; Ear, External; Female; Humans; Iridium Radioisotopes; Keloid; Male; Postoperative | 2006 |
Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis.
Topics: Benzamides; Chromones; Coculture Techniques; Connective Tissue Growth Factor; Culture Media, Conditi | 2006 |
Possible isotretinoin-induced keloids in a patient with Behçet's disease.
Topics: Acne Vulgaris; Adult; Behcet Syndrome; Drug Eruptions; Humans; Isotretinoin; Keloid; Keratolytic Age | 2006 |
Pustular psoriasis over keloids: is it a Koebner phenomenon?
Topics: Adult; Female; Hand; Humans; Keloid; Psoriasis; Thorax | 2006 |
LASIK in myopic patients with dermatological keloids.
Topics: Adult; Female; Follow-Up Studies; Humans; Keloid; Keratomileusis, Laser In Situ; Male; Myopia; Refra | 2006 |
[Relationship between the proliferation and immunoinduction of epithelial cells and the destruction of hair follicles and sebaceous glands in keloids].
Topics: Adolescent; Adult; Cell Proliferation; Child; Child, Preschool; Epithelial Cells; Female; Hair Folli | 2006 |
[Analysis of differential express gene between keloid and normal skin by suppression subtractive hybridization].
Topics: DNA, Complementary; Gene Expression; Gene Expression Profiling; Humans; Keloid; Nucleic Acid Hybridi | 2006 |
[What is true in "spontaneous" keloids?].
Topics: Humans; Keloid | 2006 |
[Linkage analysis of keloid susceptibility loci on chromosome 7p11 in a Chinese pedigree].
Topics: Adolescent; Adult; Asian People; China; Chromosomes, Human, Pair 7; Female; Genetic Linkage; Genetic | 2006 |
Intra-lesional injections of collagenase are ineffective in the treatment of keloid and hypertrophic scars.
Topics: Adult; Anti-Inflammatory Agents; Blister; Child; Cicatrix, Hypertrophic; Drug Administration Schedul | 2006 |
Smallpox vaccination site reactions: two cases of exaggerated scarring and a brief review.
Topics: Adult; Cicatrix; Female; Humans; Keloid; Male; Skin Diseases; Smallpox Vaccine | 2006 |
[Treatment of keloids with shaving and cryosurgery: preliminary reports].
Topics: Adolescent; Adult; Child; Cryosurgery; Female; Humans; Keloid; Male; Middle Aged; Retrospective Stud | 2006 |
Meatoplasty keloid: a rare lesion treated with an unusual surgical approach.
Topics: Child; Ear Diseases; Ear, External; Humans; Keloid; Male; Mastoid; Otologic Surgical Procedures; Pos | 2006 |
Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3K/AkT signaling pathways.
Topics: Camellia sinensis; Catechin; Cells, Cultured; Coculture Techniques; Collagen Type I; Fibroblasts; Hu | 2006 |
Surgical Pearl: a model to practice the Mohs surgical technique.
Topics: Carcinoma, Basal Cell; Dermatology; General Surgery; Humans; Keloid; Models, Biological; Mohs Surger | 2006 |
Upregulation of the Wnt/beta-catenin pathway induced by transforming growth factor-beta in hypertrophic scars and keloids.
Topics: Adolescent; beta Catenin; Blotting, Western; Cell Line; Child; Cicatrix, Hypertrophic; Collagen; Fem | 2006 |
Trisomy 9p associated with self-injured behaviour and multiple intractable keloids.
Topics: Abnormalities, Multiple; Adult; Chromosomes, Human, Pair 9; Female; Humans; Keloid; Self-Injurious B | 2006 |
Role of cathepsin K in the turnover of the dermal extracellular matrix during scar formation.
Topics: Cathepsin K; Cathepsins; Cells, Cultured; Cicatrix; Cytoplasm; Dermis; Endosomes; Extracellular Matr | 2007 |
Benign neoplasms/hyperplasia.
Topics: Bony Callus; Callosities; Cysts; Fibroma; Histiocytoma, Benign Fibrous; Humans; Hyperplasia; Keloid; | 2006 |
Regulation of epidermal homeostasis and repair by phosphoinositide 3-kinase.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Class I Phosphatidylinositol 3-K | 2006 |
The role of the activin system in keloid pathogenesis.
Topics: Activins; Cell Line; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Dimerizat | 2007 |
Functional implications of the IL-6 signaling pathway in keloid pathogenesis.
Topics: Adult; Cell Proliferation; Cells, Cultured; Collagen; Female; Fibroblasts; Humans; Interleukin-6; Ke | 2007 |
[Hyperplastic scars and keloids. Part I: basics and prevention].
Topics: Adult; Child; Cicatrix, Hypertrophic; Face; Female; Humans; Keloid; Male; Postoperative Care; Postop | 2006 |
Characteristics of occurrence for Han Chinese familial keloids.
Topics: Adolescent; Adult; Age of Onset; Aged; Asian People; Child; Child, Preschool; Female; Humans; Infant | 2006 |
Does transformation of microvascular endothelial cells into myofibroblasts play a key role in the etiology and pathology of fibrotic disease?
Topics: Cell Differentiation; Endothelium, Vascular; Fibroblasts; Fibrosis; Humans; Keloid; Microcirculation | 2007 |
Modulation of collagen synthesis in keloid fibroblasts by silencing Smad2 with siRNA.
Topics: Adult; Cells, Cultured; Collagen; Down-Regulation; Female; Fibroblasts; Fluorescent Antibody Techniq | 2006 |
Exogenous nitric oxide stimulated collagen type I expression and TGF-beta1 production in keloid fibroblasts by a cGMP-dependent manner.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Blotting, Western; Cells, Cultured; Collagen Type I; Cycli | 2007 |
Influence of quercetin and x-ray on collagen synthesis of cultured human keloid-derived fibroblasts.
Topics: Adult; Cells, Cultured; Collagen Type I; Collagen Type III; Dose-Response Relationship, Drug; Female | 2006 |
[Study on arachidonic acid metabolism and collagen production in keloids].
Topics: Arachidonic Acid; Cells, Cultured; Collagen; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Humans; Ke | 2006 |
A rare complication after circumcision: keloid of the penis.
Topics: Adolescent; Circumcision, Male; Humans; Keloid; Male; Penile Diseases | 2006 |
Use of a non-contact 3D digitiser to measure the volume of keloid scars: a useful tool for scar assessment.
Topics: Adult; Aged; Cicatrix, Hypertrophic; Female; Humans; Image Processing, Computer-Assisted; Keloid; La | 2007 |
Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Differentiation; Cell Proliferation; Cocult | 2007 |
Application of mitomycin-C for head and neck keloids.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Black or African American; Combined Modality Therapy | 2006 |
Cushing's syndrome secondary to intralesional steroid injections of multiple keloid scars.
Topics: Adult; Cushing Syndrome; Female; Glucocorticoids; Humans; Keloid; Recurrence; Triamcinolone | 2006 |
[Expressions of TGF-betaR I, Smad2, Smad3 and Smad7 in keloids].
Topics: Adolescent; Adult; Female; Humans; Keloid; Male; Middle Aged; Protein Serine-Threonine Kinases; Rece | 2006 |
Induction of TIMP-1 and HSP47 synthesis in primary keloid fibroblasts by exogenous nitric oxide.
Topics: Adult; Aged; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Female; Fibroblasts; HSP | 2007 |
IL-6 signaling pathway in keloids: a target for pharmacologic intervention?
Topics: Collagen; Humans; Interleukin-6; Keloid; Signal Transduction | 2007 |
TWEAK inhibits TGF-beta-induced contraction of normal and keloid fibroblast-embedded collagen gel.
Topics: Cells, Cultured; Collagen; Cytokine TWEAK; Drug Interactions; Fibroblasts; Gels; Humans; Keloid; Tra | 2007 |
Unilateral congenital corneal keloid with anterior segment mesenchymal dysgenesis and subluxated lens: case report and review of literature.
Topics: Adult; Anterior Eye Segment; Corneal Diseases; Eye Abnormalities; Humans; Keloid; Keratoplasty, Pene | 2007 |
Delayed foreign body granuloma secondary to an abandoned cardiac pacemaker wire.
Topics: Adolescent; Cyclosporine; Dermatologic Agents; Humans; Keloid; Male; Pemphigus | 2007 |
Extensive keloids following cyclosporin therapy in a pemphigus vulgaris patient.
Topics: Adolescent; Cyclosporine; Humans; Keloid; Male; Pemphigus | 2007 |
Ehlers-Danlos syndrome type IV: keloidal plaques of the lower extremities, amniotic band limb deformity, and a new mutation.
Topics: Adult; Amniotic Band Syndrome; Collagen Type III; Ehlers-Danlos Syndrome; Female; Humans; Infant, Ne | 2007 |
Objective assessment of keloid scars with three-dimensional imaging: quantifying response to intralesional steroid therapy.
Topics: Adolescent; Adult; Feasibility Studies; Female; Glucocorticoids; Humans; Imaging, Three-Dimensional; | 2007 |
Form-pressure garments for pinna keloids as a better pressure therapy.
Topics: Bandages; Ear, External; Humans; Keloid; Pressure | 2007 |
Multiple nonsyndromic spontaneous keloids in allergic disease.
Topics: Adult; Clothing; Female; Humans; Hypersensitivity; Keloid | 2007 |
Different therapeutic modalities in a patient with multiple spontaneously developed keloids--a case report.
Topics: Adult; Female; Humans; Keloid; Recurrence | 2006 |
Effect of skin surface temperature on skin pigmentation during contact and intralesional cryosurgery of keloids.
Topics: Adult; Cryosurgery; Female; Humans; Hypopigmentation; Keloid; Male; Skin Pigmentation; Skin Temperat | 2007 |
Is the treatment of keloid scars still a challenge in 2006?
Topics: Adult; Aged; Brachytherapy; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Iridium Ra | 2007 |
Etiology and management of ear lobule keloid in South India.
Topics: Ear, External; Female; Humans; India; Keloid; Male; Retrospective Studies | 2007 |
[Establishment of immortalized B-lymphoblastoid cell lines of keloid pedigree and its karyotype analysis].
Topics: B-Lymphocytes; Cell Line, Transformed; Cell Lineage; Cell Transformation, Viral; Female; Herpesvirus | 2006 |
Application of topical mitomycin C to the base of shave-removed keloid scars to prevent their recurrence.
Topics: Adult; Female; Glycopeptides; Humans; Keloid; Male; Middle Aged; Mitomycin; Nucleic Acid Synthesis I | 2007 |
[Establishment of immortal lymphoblastoid cell bank of keloids pedigree].
Topics: Adolescent; Adult; Aged; B-Lymphocytes; Cell Culture Techniques; Cell Line, Transformed; Child; Chil | 2006 |
Treatment of ear keloids by compression, using a modified oyster-splint technique.
Topics: Adolescent; Combined Modality Therapy; Ear Diseases; Ear, External; Humans; Keloid; Male; Pressure; | 2007 |
Combination therapy of a large, recurrent keloid.
Topics: Adjuvants, Immunologic; Adult; Aminoquinolines; Cicatrix, Hypertrophic; Combined Modality Therapy; G | 2007 |
Variations in gap junctional intercellular communication and connexin expression in fibroblasts derived from keloid and hypertrophic scars.
Topics: Adolescent; Adult; Cell Communication; Cells, Cultured; Cicatrix, Hypertrophic; Connexin 43; Fibrobl | 2007 |
Gli-1 oncogene: the key to keloidogenesis?
Topics: Fibroblasts; Humans; Keloid; Skin; Transcription Factors; Zinc Finger Protein GLI1 | 2007 |
Potential therapeutical effects of topical halofuginone hydrobromide in keloid management.
Topics: Administration, Topical; Cell Proliferation; Gene Expression Regulation, Enzymologic; Humans; Keloid | 2007 |
Combination of surgical excision and custom designed silicon pressure splint therapy for keloids on the helical rim.
Topics: Combined Modality Therapy; Ear Diseases; Ear, External; Female; Humans; Keloid; Pressure; Splints; S | 2007 |
Transcriptional signature of epidermal keratinocytes subjected to in vitro scratch wounding reveals selective roles for ERK1/2, p38, and phosphatidylinositol 3-kinase signaling pathways.
Topics: Biomarkers; Cell Differentiation; Cell Movement; Dermis; Enzyme Inhibitors; Gene Expression Profilin | 2007 |
[Preliminary linkage analysis and mapping of keloid susceptibility locus in a Chinese pedigree].
Topics: Asian People; Chromosome Mapping; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 18; Female; | 2007 |
mTOR as a potential therapeutic target for treatment of keloids and excessive scars.
Topics: Actins; Adolescent; Adult; Cells, Cultured; Child; Cicatrix, Hypertrophic; Collagen; Cyclin D; Cycli | 2007 |
Fas-mediated apoptotic signal transduction in keloid and hypertrophic scar.
Topics: Adolescent; Adult; Apoptosis; Cells, Cultured; Ceramides; Cicatrix, Hypertrophic; Fas Ligand Protein | 2007 |
Late results of burn wound scar after cerium nitrate-silver sulfadiazine and compressive therapy: scanning electron microscopy evaluation of a keloid scar.
Topics: Administration, Topical; Anti-Infective Agents, Local; Burns, Chemical; Cerium; Child, Preschool; Co | 2007 |
Prevalence of childhood acne, ephelides, warts, atopic dermatitis, psoriasis, alopecia areata and keloid in Kaohsiung County, Taiwan: a community-based clinical survey.
Topics: Acne Vulgaris; Alopecia Areata; Chi-Square Distribution; Child; Cross-Sectional Studies; Dermatitis, | 2007 |
Flashlamp pulsed-dye laser suppressed TGF-beta1 expression and proliferation in cultured keloid fibroblasts is mediated by MAPK pathway.
Topics: Anthracenes; Cell Proliferation; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Fibroblasts; F | 2007 |
Overview of complications secondary to tongue and lip piercings.
Topics: Adolescent; Adult; Bacterial Infections; Body Piercing; Cracked Tooth Syndrome; Gingival Recession; | 2007 |
Keloids: A viral hypothesis.
Topics: Adolescent; Cicatrix; Disease Reservoirs; Female; Humans; Keloid; Male; Models, Biological; Recurren | 2008 |
Effect of heat shock protein 47 on collagen accumulation in keloid fibroblast cells.
Topics: Adolescent; Adult; Blotting, Western; Collagen; Female; Fibroblasts; HSP47 Heat-Shock Proteins; Huma | 2007 |
Factor XIIIa-positive dermal dendritic cells in keloids and hypertrophic and mature scars.
Topics: Biomarkers; Cicatrix, Hypertrophic; Cytoplasm; Factor XIIIa; Humans; Immunoenzyme Techniques; Keloid | 2007 |
Trichilemmal carcinoma of the skin mimicking a keloid in a heart transplant recipient.
Topics: Carcinoma; Cardiomyopathies; Diagnosis, Differential; Heart Transplantation; Humans; Keloid; Male; M | 2007 |
Abnormal nuclear factor (NF)-kappaB signal pathway and aspirin inhibits tumor necrosis factor alpha-induced NF-kappaB activation in keloid fibroblasts.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Culture Techniques; Cell Proliferation | 2007 |
[Location of predisposing gene for one Han Chinese keloid pedigree].
Topics: Asian People; Chromosomes, Human, Pair 10; Fas Ligand Protein; Female; Gene Frequency; Genetic Linka | 2007 |
[Experimental gene therapy of keloid in vivo using recombinant adenovirus coding for Fas gene with steroid hormone].
Topics: Adenoviridae; Animals; Disease Models, Animal; fas Receptor; Genetic Therapy; Genetic Vectors; Hormo | 2007 |
[Mapping of the loss of heterozygosity for chromosome 1 pter-36.21 in keloid].
Topics: Adolescent; Adult; Chromosome Mapping; Chromosomes, Human, Pair 1; Female; Humans; Keloid; Loss of H | 2007 |
Head and neck keloid: treatment by core excision and delayed intralesional injection of steroid.
Topics: Adult; Black People; Child; Ear, External; Face; Female; Glucocorticoids; Humans; Injections, Intral | 2007 |
Imiquimod 5% cream for the prevention of recurrence after excision of presternal keloids.
Topics: Administration, Topical; Adult; Aminoquinolines; Combined Modality Therapy; Dose-Response Relationsh | 2007 |
Potent and selective nonpeptidic inhibitors of procollagen C-proteinase.
Topics: Administration, Cutaneous; Bone Morphogenetic Protein 1; Bone Morphogenetic Proteins; Cicatrix, Hype | 2007 |
Analysis of protease-activated receptor-1 and -2 in human scar formation.
Topics: Adolescent; Adult; Aged; Calcium; Cells, Cultured; Cicatrix; Cicatrix, Hypertrophic; Female; Fibrobl | 2007 |
[Dermatologic radiotherapy].
Topics: Eczema; Humans; Keloid; Lymphoma, B-Cell; Lymphoma, T-Cell, Cutaneous; Palliative Care; Precancerous | 2007 |
[Replication of pathological scar in nude mice].
Topics: Animals; Cicatrix, Hypertrophic; Disease Models, Animal; Keloid; Mice; Mice, Inbred BALB C; Mice, Nu | 2007 |
[The expression of periostin in hyperplasic scars and the relations to TGF-beta1 and its receptors].
Topics: Adult; Cell Adhesion Molecules; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; Receptors, Tra | 2007 |
[Genetic characteristics of six Chinese Han keloid pedigrees].
Topics: Adolescent; Adult; Age of Onset; Asian People; Child; Female; Humans; Keloid; Male; Middle Aged; Ped | 2007 |
Differential p63 and p53 expression in human keloid fibroblasts and hypertrophic scar fibroblasts.
Topics: Blotting, Western; Cells, Cultured; Cicatrix, Hypertrophic; Fibroblasts; Fluoroimmunoassay; Humans; | 2007 |
Keloids do not harbor EBV or HHV8.
Topics: Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Keloid | 2008 |
[Keloidal granular cell tumor].
Topics: Adenocarcinoma; Adult; Dermatofibrosarcoma; Diagnosis, Differential; Humans; Keloid; Male; Skin Neop | 2001 |
[Experimental study on fas gene death domain mutations in keloid pedigrees].
Topics: Cell Death; DNA; Exons; fas Receptor; Female; Fibroblasts; Humans; Keloid; Male; Mutation; Pedigree; | 2007 |
Effect of wt-P53 protein on telomerase activity in keloid fibroblasts.
Topics: Adenoviruses, Human; Blotting, Western; Fibroblasts; Fluoroimmunoassay; Humans; Keloid; Telomerase; | 2007 |
Biological differences between fibroblasts derived from peripheral and central areas of keloid tissues.
Topics: Adult; Apoptosis; Cell Cycle; Cell Proliferation; Female; Fibroblasts; Humans; Keloid; Male; Middle | 2007 |
Are keloids and hypertrophic scars caused by fungal infection?
Topics: Adult; Antifungal Agents; Cicatrix, Hypertrophic; Female; Humans; Itraconazole; Keloid; Male; Middle | 2007 |
Keloid of the conjunctiva simulating a conjunctival malignancy.
Topics: Conjunctival Diseases; Conjunctival Neoplasms; Diagnosis, Differential; Humans; Keloid; Male; Middle | 2007 |
Genomic and proteomic profiling II: comparative assessment of gene expression profiles in leiomyomas, keloids, and surgically-induced scars.
Topics: Adult; Black or African American; Cicatrix; Cluster Analysis; Female; Gene Expression; Gene Expressi | 2007 |
Intraoperative repiercing for earlobe keloid.
Topics: Body Piercing; Ear, External; Humans; Keloid; Plastic Surgery Procedures; Reoperation | 2007 |
Postoperative electron beam radiotherapy for keloids: objective findings and patient satisfaction in self-assessment.
Topics: Adult; Aged; Combined Modality Therapy; Electrons; Female; Humans; Keloid; Male; Middle Aged; Patien | 2007 |
Inhibition of Smad3 expression decreases collagen synthesis in keloid disease fibroblasts.
Topics: Adult; Cells, Cultured; Collagen Type I; Collagen Type III; Female; Fibroblasts; Humans; Keloid; Rev | 2007 |
Keloidal basal cell carcinoma.
Topics: Carcinoma, Basal Cell; Collagen; Diagnosis, Differential; Humans; Keloid; Male; Middle Aged; Skin Ne | 2007 |
A primary protocol for the management of ear keloids: results of excision combined with intraoperative and postoperative steroid injections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Body Piercing; Child; Child, Preschool; Clin | 2007 |
Multicenter study of wound healing in neurofibromatosis and neurofibroma.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Infant; Keloid; Male; Middle Aged; | 2007 |
Combined surgical excision and radiation therapy for keloid treatment.
Topics: Adolescent; Adult; Aged; Child; Combined Modality Therapy; Female; Humans; Keloid; Male; Middle Aged | 2007 |
Unilateral keloid formation after bilateral breast surgery and unilateral radiation.
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Keloid; Mastectomy, Segmental; Middle A | 2007 |
Human skin keloid fibroblasts display bioenergetics of cancer cells.
Topics: Adenosine Triphosphate; Adolescent; Adult; Antimutagenic Agents; Cell Hypoxia; Cells, Cultured; Chil | 2008 |
Inhibitors of dipeptidyl peptidase IV-like activity mediate antifibrotic effects in normal and keloid-derived skin fibroblasts.
Topics: Actins; Animals; Collagen Type I; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Diseas | 2008 |
Reticulate keloidal purpura associated with transient antiphospholipid antibodies and hyperhomocysteinaemia.
Topics: Aged; Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Female; Humans; Hyperhomocysteinemia; | 2007 |
Postoperative high-dose-rate brachytherapy in the prevention of keloids.
Topics: Adolescent; Adult; Aged; Brachytherapy; Female; Humans; Iridium Radioisotopes; Keloid; Male; Middle | 2007 |
Increased CCN2 transcription in keloid fibroblasts requires cooperativity between AP-1 and SMAD binding sites.
Topics: Adolescent; Adult; Binding Sites; Cell Culture Techniques; Connective Tissue Growth Factor; Cysteine | 2007 |
Mass spectrometric characterization of cholesterol esters and wax esters in epidermis of fetal, adult and keloidal human skin.
Topics: Adult; Age Factors; Ceramides; Cholesterol Esters; Chromatography, Thin Layer; Epidermis; Fatty Acid | 2008 |
Adjuvant radiation of bilateral postauricular keloids: an illustration of technique.
Topics: Adult; Ear, External; Humans; Keloid; Male; Radiotherapy; Recurrence | 2007 |
[Instead of jewelry hard nodules on the ears].
Topics: Adult; Ear, External; Female; Humans; Keloid; Recurrence; Reoperation | 2007 |
Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways.
Topics: Cells, Cultured; Dermis; Fibroblasts; Fibrosis; Gene Expression Profiling; Humans; Keloid; Oligonucl | 2008 |
[Experimental gene therapy of keloid in vivo using recombinant adenovirus carrying Fas gene].
Topics: Adenoviridae; Animals; Disease Models, Animal; fas Receptor; Female; Genetic Therapy; Genetic Vector | 2007 |
Targeting of Sp1 transcription factor: a novel therapeutic approach for keloids, an in vitro analysis.
Topics: Antineoplastic Agents; Case-Control Studies; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cocu | 2007 |
Cytologic appearance of a keloidal fibrosarcoma in a dog.
Topics: Animals; Dog Diseases; Dogs; Fibrosarcoma; Keloid; Male | 2007 |
So what is a keloid scar?
Topics: Cicatrix, Hypertrophic; Evidence-Based Medicine; Humans; Keloid | 2008 |
Use of organotypic coculture to study keloid biology.
Topics: Cells, Cultured; Coculture Techniques; Fibroblasts; Humans; Immunohistochemistry; Keloid; Keratinocy | 2008 |
Transforming growth factor-beta1-antisense modulates the expression of hepatocyte growth factor/scatter factor in keloid fibroblast cell culture.
Topics: Adult; Blotting, Western; Cicatrix; DNA, Antisense; Female; Fibroblasts; Hepatocyte Growth Factor; H | 2008 |
Restylane and people of color.
Topics: Cicatrix, Hypertrophic; Cosmetic Techniques; Female; Genetic Predisposition to Disease; Humans; Hyal | 2007 |
Management of external ear keloids using form-pressure therapy.
Topics: Adolescent; Adult; Aged; Bandages; Ear Deformities, Acquired; Ear, External; Equipment Design; Femal | 2008 |
For the therapy of the keloids, with special consideration of the radium treatment.
Topics: Humans; Keloid; Neoplasms | 1948 |
Keloids and hypertrophic scars.
Topics: Cicatrix; Cicatrix, Hypertrophic; Humans; Keloid | 1948 |
[Association between p53 gene codon 72 polymorphism and keloid in Chinese population].
Topics: Asian People; Codon; Female; Humans; Keloid; Male; Polymorphism, Restriction Fragment Length; Tumor | 2007 |
Diagnosis and management of corneal keloid.
Topics: Adult; Biological Dressings; Cataract; Cataract Extraction; Corneal Diseases; Eye Injuries; Follow-U | 2007 |
Treatment of recurrent earlobe keloids with surgery and high-dose-rate brachytherapy.
Topics: Adolescent; Adult; Brachytherapy; Ear, External; Female; Humans; Keloid; Male; Middle Aged; Recurren | 2008 |
Long-term follow-up in the treatment of keloids by combined surgical excision and immediate postoperative adjuvant irradiation.
Topics: Humans; Keloid; Postoperative Period; Radiotherapy, Adjuvant | 2008 |
Treatment of postdermabrasion facial hypertrophic and keloid scars with intralesional 5-Fluorouracil injections.
Topics: Aged; Antimetabolites, Antineoplastic; Cicatrix, Hypertrophic; Face; Female; Fluorouracil; Humans; I | 2008 |
Nerve fibres: a possible role in keloid pathogenesis.
Topics: Adolescent; Adult; Female; Humans; Immunohistochemistry; Keloid; Middle Aged; Nerve Fibers; Treatmen | 2008 |
Keloidal basal cell carcinoma.
Topics: Carcinoma, Basal Cell; Humans; Keloid; Skin Neoplasms | 2008 |
Should excised keloid scars be sent for routine histologic analysis?
Topics: Diagnostic Tests, Routine; Humans; Keloid | 2008 |
Oxygen consumption of keloids and hypertrophic scars.
Topics: Animals; Cicatrix, Hypertrophic; Humans; Keloid; Male; Mice; Mice, Inbred Strains; Oxygen Consumptio | 2008 |
Inhibition of vascular endothelial growth factor expression in keloid fibroblasts by vector-mediated vascular endothelial growth factor shRNA: a therapeutic potential strategy for keloid.
Topics: Adolescent; Adult; Cells, Cultured; Down-Regulation; Female; Fibroblasts; Genetic Therapy; Genetic V | 2008 |
Keloid scar harbouring malignant blue naevus emphasises the need for excision biopsy and routine histology.
Topics: Aged; Diagnosis, Differential; Ear Neoplasms; Ear, External; Humans; Keloid; Male; Melanoma; Nevus, | 2009 |
Descriptive study of patients receiving excision and radiotherapy for keloids.
Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Female; Health Care Surveys; Humans; Keloid; Mal | 2008 |
The results of surgical excision and adjuvant irradiation for therapy-resistant keloids: a prospective clinical outcome study.
Topics: Follow-Up Studies; Humans; Keloid; Plastic Surgery Procedures; Prospective Studies; Radiotherapy, Ad | 2008 |
Pressure therapy with a round rod for hypertrophic scars: reply.
Topics: Cicatrix, Hypertrophic; Dermatology; Humans; Keloid; Pressure; Time Factors | 2008 |
Long-term follow-up in the treatment of keloids by combined surgical excision and immediate postoperative adjuvant irradiation.
Topics: Follow-Up Studies; Humans; Keloid; Plastic Surgery Procedures; Postoperative Period; Radiotherapy, A | 2008 |
Keloid formation resulting in acquired syndactyly of an initially normal web space following syndactyly release of an adjacent web space.
Topics: Child; Humans; Immunosuppressive Agents; Keloid; Male; Methotrexate; Postoperative Complications; Re | 2008 |
Efficacy of recombinant adenovirus-mediated double suicide gene therapy in human keloid fibroblasts.
Topics: Adenoviruses, Human; Apoptosis; Bystander Effect; Cell Line; Cell Proliferation; DNA, Recombinant; F | 2008 |
Keloids: when excision is the better part of valor.
Topics: Adult; Female; Humans; Keloid; Plastic Surgery Procedures | 2008 |
Postoperative radiation therapy for keloid.
Topics: Humans; Keloid; Postoperative Care | 2008 |
[Synthetic therapy for keloid in aural region].
Topics: Adolescent; Adult; Combined Modality Therapy; Ear, External; Female; Glucocorticoids; Humans; Keloid | 2008 |
The relationship between keloid growth pattern and stretching tension: visual analysis using the finite element method.
Topics: Cicatrix; Finite Element Analysis; Humans; Keloid; Skin; Tensile Strength; Wound Healing | 2008 |
The relationship between keloid growth pattern and stretching tension-visual analysis using the finite element method: a brief history of keloids.
Topics: Finite Element Analysis; History, 20th Century; Humans; Keloid; Models, Anatomic; Tensile Strength | 2008 |
A novel truncated TGF-beta receptor II downregulates collagen synthesis and TGF-beta I secretion of keloid fibroblasts.
Topics: Cell Proliferation; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Down-Regulation; Fi | 2008 |
Keloid scars--an avoidable complication of vaccination.
Topics: Adolescent; Adult; BCG Vaccine; Female; Humans; Keloid; Tuberculosis | 2008 |
Keloid and hypertrophic scar: neurogenic inflammation hypotheses.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Mechanoreceptors; Models, Biological; Neurogenic Inflammatio | 2008 |
DHMEQ, a novel NF-kappaB inhibitor, suppresses growth and type I collagen accumulation in keloid fibroblasts.
Topics: Benzamides; Cell Division; Cells, Cultured; Collagen Type I; Cyclohexanones; DNA; Fibroblasts; Human | 2008 |
Two peculiar conditions following a coma: a clinical case of heterotopic ossification concomitant with keloid formation.
Topics: Adult; Ankylosis; Cicatrix, Hypertrophic; Coma; Humans; Humerus; Imaging, Three-Dimensional; Keloid; | 2008 |
[Pharmacological therapy of keloids in an athymic mouse model].
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Colchicine; Data Interpretation, Stati | 2008 |
[The role of cell pathway in apoptosis of fibroblasts from proliferative scar induced by steroid or IFN].
Topics: Adult; Apoptosis; Cells, Cultured; Cicatrix, Hypertrophic; Female; Fibroblasts; Hormones; Humans; In | 2008 |
Genetic susceptibility to keloid scarring: SMAD gene SNP frequencies in Afro-Caribbeans.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Black People; Case-Control Studies; Child; Child, Presch | 2008 |
Prefabricated pressure earring for earlobe keloids.
Topics: Ear Auricle; Equipment Design; Humans; Keloid; Polymethyl Methacrylate; Pressure; Splints; Surface P | 2008 |
Rapid recurrence of keloid after pulse dye laser treatment.
Topics: Adult; Female; Humans; Keloid; Laser Therapy; Lasers, Dye; Recurrence | 2008 |
Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway.
Topics: Animals; Catechin; Cell Cycle; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Fibrobl | 2008 |
Experiences with a solid state detector for surface counting of phosphorus-32.
Topics: Ciliary Body; Eye Neoplasms; Humans; Keloid; Melanoma; Neoplasm Metastasis; Phosphorus Isotopes; Rad | 1967 |
[Distant effect in the cure of a keloid with hydrocortisone injections].
Topics: Humans; Hydrocortisone; Keloid | 1967 |
Strophulus in Indonesia.
Topics: Adolescent; Child; Dermatologic Agents; Female; Humans; Indonesia; Insect Bites and Stings; Insect R | 1967 |
Intralesional injection of keloids and hypertrophic scars with the Dermo-Jet.
Topics: Adolescent; Adult; Aged; Cicatrix; Female; Humans; Hyaluronoglucosaminidase; Hypertrophy; Injections | 1967 |
Keloids containing hair and sebaceous glands.
Topics: Adult; Female; Hair; Humans; Keloid; Sebaceous Glands; Smallpox Vaccine; Vaccination | 1967 |
[On mechanical removal of papillomas of the larynx in children].
Topics: Child; Child, Preschool; Fibroma; Humans; Inhalation; Keloid; Laryngeal Neoplasms; Laryngoscopy | 1967 |
Regression of massive keloid following partial excision and post-operative intralesional administration of triamcinolone.
Topics: Child; Ear Deformities, Acquired; Ear Diseases; Ear, External; Humans; Keloid; Male; Triamcinolone A | 1967 |
Connective tissue diseases.
Topics: Collagen; Collagen Diseases; Connective Tissue Diseases; Elastic Tissue; Elastin; Humans; Keloid; Mi | 1984 |
The use of antihistamine to retard the growth of fibroblasts derived from human skin, scar, and keloid.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Cicatrix; Female; Fibroblasts; Histamin | 1981 |
The antihistamine treatment of keloids.
Topics: Animals; Guinea Pigs; Histamine H1 Antagonists; Keloid | 1982 |
Gene mapping and serendipity. The locus for torticollis, keloids, cryptorchidism and renal dysplasia (31430, Mckusick) is at Xq28, distal to the G6PD locus.
Topics: Abnormalities, Multiple; Chromosome Mapping; Cryptorchidism; Female; Glucosephosphate Dehydrogenase; | 1982 |
[Electron microscopic and autoradiographic study of keloid scars].
Topics: Adult; Autoradiography; Burns; Cell Differentiation; Female; Histocytochemistry; Humans; Keloid; Mal | 1982 |
Studies on the immunologic aspects of keloids and hypertrophic scars.
Topics: Adolescent; Adult; Animals; Antibodies, Antinuclear; Child; Cicatrix; Fibroblasts; Fluorescent Antib | 1982 |
Clinical features and treatment of bilateral cicatrical deformities of the eyelids.
Topics: Adolescent; Adult; Cicatrix; Eye Burns; Eyelids; Female; Humans; Keloid; Male; Surgery, Plastic | 1984 |
Delayed type hypersensitivity reaction to cutaneous antigen in keloid.
Topics: Acne Vulgaris; Adolescent; Adult; Female; Humans; Hypersensitivity, Delayed; Isoantigens; Keloid; Ma | 1982 |
Immunofluorescence findings in haematoporphyrin-induced keloid.
Topics: Adult; Complement System Proteins; Drug Eruptions; Female; Fibroblasts; Fluorescent Antibody Techniq | 1983 |
Hair and scalp disorders in blacks.
Topics: Alopecia; Black People; Cellulitis; Dermatitis, Seborrheic; Folliculitis; Hair Diseases; Hair Prepar | 1983 |
In vitro inhibition of cell growth, collagen synthesis, and prolyl hydroxylase activity by triamcinolone acetonide.
Topics: Cell Division; Cell Line; Collagen; DNA; Humans; Keloid; Procollagen-Proline Dioxygenase; Skin; Tria | 1980 |
[After care of scar formation].
Topics: Aftercare; Cicatrix; Humans; Keloid; Wound Healing | 1980 |
Collagenase in keloid biopsies and fibroblasts.
Topics: Adolescent; Adult; Biopsy; Collagen; Female; Fibroblasts; Humans; Keloid; Male; Microbial Collagenas | 1982 |
Bacterial collagenases and their clinical applications.
Topics: Animals; Burns; Clostridium; Humans; Keloid; Microbial Collagenase; Skin Ulcer; Vitreous Body | 1982 |
Variation in prolyl hydroxylase activity of keloid-derived and normal human fibroblasts in response to hydrocortisone and ascorbic acid.
Topics: Ascorbic Acid; Culture Techniques; DNA; Fibroblasts; Humans; Hydrocortisone; Keloid; Procollagen-Pro | 1983 |
Fibronectin (FN) in hypertrophic scars and keloids.
Topics: Cells, Cultured; Cicatrix; Fibroblasts; Fibronectins; Fluorescent Antibody Technique; Humans; Keloid | 1983 |
Immunoglobulins in hypertrophic scars and keloids.
Topics: Albumins; Cicatrix; Complement C3; Complement C4; Fibrin; Fluorescent Antibody Technique; Humans; Hy | 1983 |
Complications associated with skin graft vestibuloplasty. Experiences with 100 cases.
Topics: Airway Obstruction; Cicatrix; Deglutition Disorders; Humans; Keloid; Mouth Floor; Periosteum; Saliva | 1983 |
[The hypertrophic scar].
Topics: Bandages; Cicatrix; Combined Modality Therapy; Humans; Keloid; Keratolytic Agents; Pressure; Surgery | 1983 |
Glucocorticoid receptors in human fibroblasts derived from normal dermis and keloid tissue.
Topics: Amino Acids; Binding, Competitive; Biological Transport, Active; Dexamethasone; Fibroblasts; Humans; | 1984 |
Argon and carbon dioxide laser treatment of hypertrophic and keloid scars.
Topics: Argon; Carbon Dioxide; Cicatrix; Humans; Hypertrophy; Keloid; Laser Therapy; Wound Healing | 1984 |
Cutaneous plastic surgery with the CO2 laser.
Topics: Biopsy; Carbon Dioxide; Cicatrix; Female; Hemangioma; Humans; Keloid; Keratosis; Laser Therapy; Lent | 1984 |
Preliminary results of argon and carbon dioxide laser treatment of keloid scars.
Topics: Argon; Carbon Dioxide; Ear, External; Female; Follow-Up Studies; Humans; Keloid; Laser Therapy; Male | 1984 |
[Prevalence of hypertrophic and keloid scars according to the site of administration of intradermal BCG vaccine].
Topics: Adolescent; Adult; BCG Vaccine; Child; Cicatrix; Cuba; Female; Humans; Hypertrophy; Injections, Intr | 1980 |
[Treatment of hypertrophic scars and keloids with Orgotein].
Topics: Adult; Burns; Cicatrix; Humans; Hypertrophy; Keloid; Male; Skin; Superoxide Dismutase | 1984 |
Hydrocortisone induction of system A amino acid transport in human fibroblasts from normal dermis and keloid.
Topics: Amino Acids; Aminoisobutyric Acids; Biological Transport, Active; Fibroblasts; Humans; Hydrocortison | 1984 |
Physical therapists as scar modifiers.
Topics: Adult; Bandages; Burns; Child; Clothing; Female; Humans; Keloid; Male; Physical Therapy Modalities; | 1984 |
BCG complications. Estimates of the risks among vaccinated subjects and statistical analysis of their main characteristics.
Topics: BCG Vaccine; Dose-Response Relationship, Drug; Humans; Keloid; Lymphadenitis; Mycobacterium Infectio | 1984 |
Embedded foreign bodies presenting as earlobe keloids.
Topics: Adolescent; Ear, External; Female; Foreign Bodies; Humans; Keloid | 1984 |
[Scanning electron microscopic observations and analysis of growth kinetics of the fibroblasts in vitro--comparison between normal skin and abnormal scars].
Topics: Adolescent; Adult; Aged; Cell Cycle; Child, Preschool; Cicatrix; Culture Techniques; Female; Fibrobl | 1984 |
Nodular (keloidal) scleroderma.
Topics: Adolescent; Adult; Biopsy; Female; Humans; Keloid; Male; Scleroderma, Systemic; Skin | 1984 |
[Hypertrophic scar and keloid. I. Etiology, pathogenesis, pathology].
Topics: Cicatrix; Collagen; Connective Tissue; Fibroblasts; Humans; Hypertrophy; Keloid; Wound Healing | 1984 |
[Hypertrophic scar and keloid. II. Light and electron microscopy studies].
Topics: Adult; Child; Child, Preschool; Cicatrix; Collagen; Connective Tissue; Female; Humans; Hypertrophy; | 1984 |
[Grenz rays in the treatment of hypertrophic scars].
Topics: Adolescent; Adult; Cicatrix; Female; Humans; Hypertrophy; Keloid; Male; Middle Aged | 1984 |
Control of connective tissue metabolism by lasers: recent developments and future prospects.
Topics: Animals; Cells, Cultured; Collagen; Connective Tissue; Fibroblasts; Humans; Keloid; Laser Therapy; S | 1984 |
Burn scars. Fighting the effects.
Topics: Adult; Bandages; Burns; Child; Cicatrix; Contracture; Cosmetics; Exercise Therapy; Humans; Keloid; P | 1983 |
Prosthetic treatment of earlobe keloids.
Topics: Ear, External; Humans; Keloid; Pressure; Prostheses and Implants; Prosthesis Design | 1984 |
General immune reactivity in keloid patients.
Topics: Adult; Complement C3; Complement C4; Complement System Proteins; Female; Humans; Immunoglobulin A; I | 1984 |
Complications of parotidectomy.
Topics: Facial Nerve Injuries; Hemorrhage; Humans; Keloid; Neoplasm Recurrence, Local; Parotid Gland; Postop | 1983 |
Pressure garments in the prevention and treatment of keloids.
Topics: Burns; Cicatrix; Contracture; Follow-Up Studies; Humans; Keloid; Postoperative Complications; Pressu | 1983 |
Treatment of keloids with excision and postoperative X-ray irradiation.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Radiation; Ear Diseases; Ear, External; | 1983 |
Burns in the elderly: an early surgical approach.
Topics: Aged; Burns; Female; Follow-Up Studies; Humans; Keloid; Male; Middle Aged; Surgical Procedures, Oper | 1983 |
Hypertrophic burn scars: analysis of variables.
Topics: Aging; Burns; Cicatrix; Clothing; Humans; Keloid; Racial Groups; Risk; Time Factors; Wound Healing | 1983 |
Hypertrophic burn scars: analysis of variables.
Topics: Aging; Burns; Cicatrix; Clothing; Humans; Keloid; Racial Groups; Risk; Time Factors; Wound Healing | 1983 |
Hypertrophic burn scars: analysis of variables.
Topics: Aging; Burns; Cicatrix; Clothing; Humans; Keloid; Racial Groups; Risk; Time Factors; Wound Healing | 1983 |
Hypertrophic burn scars: analysis of variables.
Topics: Aging; Burns; Cicatrix; Clothing; Humans; Keloid; Racial Groups; Risk; Time Factors; Wound Healing | 1983 |
Hypertrophic burn scars: analysis of variables.
Topics: Aging; Burns; Cicatrix; Clothing; Humans; Keloid; Racial Groups; Risk; Time Factors; Wound Healing | 1983 |
Hypertrophic burn scars: analysis of variables.
Topics: Aging; Burns; Cicatrix; Clothing; Humans; Keloid; Racial Groups; Risk; Time Factors; Wound Healing | 1983 |
Hypertrophic burn scars: analysis of variables.
Topics: Aging; Burns; Cicatrix; Clothing; Humans; Keloid; Racial Groups; Risk; Time Factors; Wound Healing | 1983 |
Hypertrophic burn scars: analysis of variables.
Topics: Aging; Burns; Cicatrix; Clothing; Humans; Keloid; Racial Groups; Risk; Time Factors; Wound Healing | 1983 |
Hypertrophic burn scars: analysis of variables.
Topics: Aging; Burns; Cicatrix; Clothing; Humans; Keloid; Racial Groups; Risk; Time Factors; Wound Healing | 1983 |
Cryotherapy in the treatment of keloids.
Topics: Adolescent; Adult; Burns; Child; Cryosurgery; Humans; Keloid; Male | 1983 |
[Etiologic approach to keloids].
Topics: Adult; Age Factors; Female; Humans; Keloid; Male; Pregnancy | 1983 |
Increased androgen binding in keloids: a preliminary communication.
Topics: Adult; Androgen-Binding Protein; Carrier Proteins; Cytosol; Dihydrotestosterone; Estradiol; Female; | 1983 |
Cosmetic defects.
Topics: Burns; Calcinosis; Catheterization; Cicatrix; Esthetics; Follow-Up Studies; Humans; Iatrogenic Disea | 1984 |
Management of uterine fibroids at the University of Benin Teaching Hospital.
Topics: Adult; Age Factors; Female; Hospitalization; Humans; Hysterectomy; Infertility, Female; Keloid; Leio | 1984 |
Multiple cell origin of traumatically induced keloids.
Topics: Adolescent; Adult; Blood Cells; Cell Division; Female; Fibroblasts; Glucosephosphate Dehydrogenase; | 1984 |
[Use of low temperatures in pediatric surgery].
Topics: Child; Child, Preschool; Cryosurgery; Endoscopes; Hemangioma; Humans; Infant; Keloid; Respiratory Tr | 1984 |
Comparative ultrastructure of hypertrophic scars and keloids.
Topics: Cell Membrane; Cicatrix; Fibroblasts; Humans; Hypertrophy; Keloid; Microscopy, Electron; Microscopy, | 1984 |
Keloids and hypertrophic scars--immunological aspects.
Topics: Adolescent; Adult; Antibodies, Antinuclear; Child; Cicatrix; Fibroblasts; Fluorescent Antibody Techn | 1982 |
The surgical treatment of keloids.
Topics: Female; Humans; Keloid; Postoperative Care; Skin Transplantation; Surgical Flaps; Triamcinolone Acet | 1982 |
[Bullous photodermatosis with pseudokeloidal development and horizontal band keratitis: hydroa vacciniforme?].
Topics: Adult; Child, Preschool; Diagnosis, Differential; Humans; Hydroa Vacciniforme; Keloid; Keratitis; Ma | 1982 |
A comparison of spring and CO2- powered needleless injectors in the treatment of keloids with triamcinolone.
Topics: Carbon Dioxide; Humans; In Vitro Techniques; Injections, Jet; Keloid; Syringes; Triamcinolone Aceton | 1981 |
"Oyster splints": a new compression device for the treatment of keloid scars of the ear.
Topics: Ear Deformities, Acquired; Female; Humans; Keloid; Male; Methods; Methylmethacrylates; Splints | 1983 |
Keloidal calcification.
Topics: Aged; Calcinosis; Female; Humans; Keloid; Skin Diseases | 1983 |
Cyro corner. A cryoprobe for the therapy of linear keloid.
Topics: Cryosurgery; Humans; Keloid | 1983 |
Activation of pulmonary tuberculosis following intralesional corticosteroids.
Topics: Adult; Humans; Injections; Keloid; Male; Radiography; Triamcinolone Acetonide; Tuberculosis, Pulmona | 1983 |
Keloids of the earlobes: a surgical technique.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Black People; Collagen; Ear Diseases; Ear, External; Fem | 1983 |
[1st observations on the side effects of soft-laser therapy].
Topics: Female; Humans; Keloid; Laser Therapy; Lasers; Pain; Sensation; Tachycardia; Voice Quality | 1983 |
Ultrasound therapy for keloids.
Topics: Humans; Keloid; Male; Ultrasonic Therapy | 1983 |
[Xanthoma tuberosum multiplex resulting in keloid cicatrices].
Topics: Diabetes Insipidus; Humans; Keloid; Male; Middle Aged; Skin; Xanthomatosis | 1983 |
Complications in head and neck surgery.
Topics: Bacterial Infections; Burns; Chylothorax; Fistula; Head; Hemorrhage; Humans; Keloid; Neck; Postopera | 1983 |
The treatment of earlobe keloids by surgical excision and postoperative triamcinolone injection.
Topics: Adolescent; Adult; Ear Diseases; Female; Follow-Up Studies; Humans; Injections, Intradermal; Keloid; | 1983 |
[Keloids: possibility of treatment by cryotherapy].
Topics: Cryosurgery; Humans; Keloid | 1983 |
Lowe's syndrome.
Topics: Child; Child, Preschool; Cornea; Corneal Diseases; Female; Genes, Recessive; Humans; Infant, Newborn | 1982 |
Preventing hypertrophic scarring: a burning issue.
Topics: Bandages; Burns; Child, Preschool; Cicatrix; Humans; Hypertrophy; Infant; Keloid; Male; Skin | 1981 |
Ethnic aspects of boxing and the ringside physician.
Topics: Black or African American; Boxing; Hernia, Umbilical; Humans; Hypertension; Keloid; Sickle Cell Trai | 1981 |
[Free transplantation of composite skin grafts].
Topics: Adult; Animals; Cadaver; Dogs; Female; Groin; Humans; Keloid; Male; Microsurgery; Postoperative Care | 1981 |
Keloid.
Topics: Dermatology; France; History, 18th Century; History, 19th Century; Humans; Keloid | 1981 |
[Late local complications in burn patients].
Topics: Burns; Cicatrix; Humans; Keloid; Skin Transplantation; Skin Ulcer; Time Factors | 1981 |
Unusual cutaneous reactions to injections of corticosteroids.
Topics: Adrenal Cortex Hormones; Adult; Female; Foreign-Body Reaction; Histiocytes; Humans; Injections, Subc | 1982 |
Keloid formation after BCG vaccination.
Topics: Adolescent; BCG Vaccine; Child; Female; Humans; Keloid; Male; Shoulder; Vaccination | 1982 |
[2 cases of keloid diathesis in one family].
Topics: Adult; Disease Susceptibility; Epilepsy; Female; Heart Defects, Congenital; Humans; Keloid; Male; Sy | 1982 |
Corneal keloids--a histopathological study.
Topics: Adolescent; Adult; Black or African American; Child; Child, Preschool; Cornea; Corneal Diseases; Fem | 1982 |
Dosimetry of auricular keloid irradiation.
Topics: Adolescent; Adult; Child; Ear, External; Humans; Keloid; Middle Aged; Radiation Injuries; Radiothera | 1982 |
Perivascular myofibroblasts and microvascular occlusion in hypertrophic scars and keloids.
Topics: Capillaries; Cicatrix; Constriction, Pathologic; Endothelium; Fibroblasts; Granulation Tissue; Human | 1982 |
Alteration of amino acid transport by hydrocortisone. Different effects in human fibroblasts derived from normal skin and keloid.
Topics: Amino Acids; Aminoisobutyric Acids; Ascorbic Acid; Biological Transport; Cell Cycle; Cells, Cultured | 1982 |
Fibroblast heterogeneity in glucocorticoid regulation of collagen metabolism: genetic or epigenetic?
Topics: Cells, Cultured; Collagen; Fibroblasts; Humans; Hydrocortisone; Keloid; Skin | 1982 |
Wound healing: a review. IV. Systemic medications affecting wound healing.
Topics: Adrenal Cortex Hormones; Aminopropionitrile; Animals; Anti-Inflammatory Agents; Anticoagulants; Anti | 1982 |
Scar revision.
Topics: Cicatrix; Dermatologic Surgical Procedures; Humans; Keloid; Surgery, Plastic | 1982 |
Hyperparathyroidism due to a cystic parathyroid adenoma after irradiation of the neck.
Topics: Adenoma; Female; Humans; Hyperparathyroidism; Keloid; Middle Aged; Neck; Neoplasms, Radiation-Induce | 1982 |
Prevention and treatment of earlobe keloids.
Topics: Ear, External; Humans; Keloid; Surgery, Plastic | 1982 |
Radiotherapy for keloids.
Topics: Adolescent; Adult; Carcinoma; Child; Humans; Keloid; Male; Radiotherapy; Thyroid Neoplasms | 1982 |
Botryomycosis in pierced ears.
Topics: Adult; Beauty; Ear; Ear Diseases; Female; Humans; Injections, Intradermal; Keloid; Postoperative Com | 1982 |
Corneal keloid in Lowe's syndrome.
Topics: Child; Cornea; Corneal Diseases; Humans; Keloid; Male; Oculocerebrorenal Syndrome; Renal Tubular Tra | 1982 |
The response of keloid scars to cryosurgery.
Topics: Adolescent; Adult; Child; Cicatrix; Cryosurgery; Humans; Keloid | 1982 |
Keloids--their epidemiology and treatment.
Topics: Adolescent; Adult; Age Factors; Child; Humans; Keloid; Racial Groups; Wound Healing; Wounds and Inju | 1982 |
[Lobomyeosis. Presentation of a case and review of the Colombian literature].
Topics: Adult; Birefringence; Blastomycosis; Colombia; Female; Humans; Keloid; Male; Middle Aged; Mitosporic | 1982 |
Treatment of keloids and hypertrophic scars with adhesive zinc tape.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix; Female; Humans; Hypertrophy; Keloid; Mal | 1982 |
Treatment of keloid scars by combined cryosurgery and intralesional corticosteroids.
Topics: Adolescent; Adult; Cryosurgery; Ear, External; Female; Humans; Keloid; Male; Middle Aged; Triamcinol | 1982 |
Effects of density and cellular aging on collagen synthesis and growth kinetics in keloid and normal skin fibroblasts.
Topics: Adolescent; Adult; Biopsy; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Collagen; Huma | 1982 |
Hypertrophic scars and keloids: a review and new concept concerning their origin.
Topics: Cell Membrane; Cicatrix; Collagen; Humans; Hypertrophy; Keloid; Microscopy, Electron; Microscopy, El | 1982 |
[Treatment of keloid scars by combined cryosurgery and intralesional corticosteroids].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Cicatrix; Cryosurgery; Female; Humans; Keloid; Ma | 1980 |
Effects of various sera on growth kinetics and collagen synthesis by keloid and normal dermal fibroblasts.
Topics: Cell Division; Cells, Cultured; Collagen; Fibroblasts; Humans; Keloid; Kinetics; Skin; Skin Physiolo | 1981 |
[Formation and treatment of pathologic scars--clinical and micromorphologic investigations (author's transl)].
Topics: Adolescent; Adult; Betaine; Child; Cicatrix; Collagen; Drug Combinations; Female; Glycosaminoglycans | 1981 |
Pharmacologic control of surface scarring in human beings.
Topics: Adolescent; Adult; Aged; Aminopropionitrile; Child; Cicatrix; Colchicine; Drug Administration Schedu | 1981 |
[Contraindication of operations for keloid scars occurring after BCG administration].
Topics: Adolescent; BCG Vaccine; Child; Chronic Disease; Female; Humans; Keloid; Recurrence | 1981 |
Rubinstein-Taybi syndrome. Cutaneous manifestations and colossal keloids.
Topics: Abnormalities, Multiple; Adult; Female; Humans; Keloid; Rubinstein-Taybi Syndrome; Skin; Skin Abnorm | 1981 |
In-office care of postoperative incisions.
Topics: Ambulatory Care; Fistula; Hernia; Humans; Intestinal Fistula; Keloid; Postoperative Care; Postoperat | 1981 |
Mucin-like changes in keloids.
Topics: Granuloma; Humans; Keloid; Mucins; Nasal Mucosa | 1981 |
Keloid formation after patch tests.
Topics: Child; Dermatitis, Contact; Humans; Keloid; Male; Nickel; Potassium Dichromate | 1981 |
Treatment of keloids by combined surgical excision and immediate postoperative X-ray therapy.
Topics: Female; Humans; Keloid; Male; Postoperative Care; Prospective Studies; Recurrence; Surgery, Plastic | 1981 |
[Treatment of postburn cicatricial deformations of the neck].
Topics: Burns; Cicatrix; Humans; Keloid; Neck Injuries; Preanesthetic Medication; Surgical Flaps | 1981 |
Structure of the collagen nodule from hypertrophic scars and keloids.
Topics: Cicatrix; Collagen; Connective Tissue; Humans; Hypertrophy; Keloid; Microcirculation; Microscopy, El | 1981 |
Facial keloids and their management.
Topics: Adolescent; Adult; Black People; Child; Collagen; Collagen Diseases; Ear, External; Facial Dermatose | 1981 |
Tissue mast cells in keloidal scars.
Topics: Adolescent; Adult; Child; Female; Humans; Keloid; Male; Mast Cells; Skin | 1981 |
Treating keloids by surgery and methotrexate.
Topics: Humans; Keloid; Methotrexate | 1980 |
Crippling giant keloid.
Topics: Chin; Hemorrhage; Humans; Keloid; Male; Middle Aged | 1980 |
[Nodular scleroderma].
Topics: Diagnosis, Differential; Humans; Keloid; Male; Middle Aged; Scleroderma, Systemic | 1980 |
The ultrastructure of a keloid.
Topics: Breast Diseases; Collagen; Cytoplasm; Female; Fibroblasts; Humans; Keloid; Microscopy, Electron; Mid | 1980 |
Triamcinolone and keloids.
Topics: Humans; Injections; Keloid; Triamcinolone; Triamcinolone Acetonide | 1980 |
Misconceptions regarding elective plastic surgery in the black patient.
Topics: Black or African American; Humans; Keloid; Postoperative Complications; Surgery, Plastic | 1980 |
The local treatment of hypertrophic scars and keloids with topical retinoic acid.
Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix; Female; Humans; | 1980 |
Rubinstein-Taybi syndrome and spontaneous keloids.
Topics: Abnormalities, Multiple; Adult; Humans; Keloid; Male; Rubinstein-Taybi Syndrome | 1980 |
Mucin-like changes in keloids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Female; Humans; Keloid; Male; Mucins | 1981 |
[Tracheal stenosis and keloid disposition (author's transl)].
Topics: Adolescent; Adult; Cicatrix; Female; Humans; Intubation, Intratracheal; Keloid; Male; Methods; Trach | 1980 |
Secondary reconstructive surgery in burns.
Topics: Adolescent; Adult; Age Factors; Burns; Child; Child, Preschool; Cicatrix; Contracture; Humans; Keloi | 1980 |
Hyaluronic acid metabolism in keloid fibroblasts.
Topics: Adolescent; Adult; Alcian Blue; Cells, Cultured; Collagen; Coloring Agents; Extracellular Matrix; Fi | 1995 |
[Treatment of a keloid of the earlobe].
Topics: Ear, External; Humans; Keloid; Methods; Pressure | 1995 |
[Use of ultra high-frequency electromagnetic fields in pediatric surgery].
Topics: Animals; Child, Preschool; Combined Modality Therapy; Cryosurgery; Electromagnetic Fields; Hemangiom | 1994 |
[A new method to determine the type of scar-changed tissue].
Topics: Acoustics; Adolescent; Atrophy; Child; Child, Preschool; Cicatrix; Cicatrix, Hypertrophic; Diagnosis | 1994 |
The distribution of hyaluronan in human skin and mature, hypertrophic and keloid scars.
Topics: Adolescent; Adult; Aged; Carrier Proteins; Child; Cicatrix; Cicatrix, Hypertrophic; Female; Humans; | 1994 |
Tranilast, a selective inhibitor of collagen synthesis in human skin fibroblasts.
Topics: Adolescent; Adult; Aged; Cells, Cultured; Collagen; Female; Fibroblasts; Histamine H1 Antagonists; H | 1994 |
Tranilast inhibits collagen synthesis in normal, scleroderma and keloid fibroblasts at a late passage culture but not at an early passage culture.
Topics: Cells, Cultured; Cellular Senescence; Collagen; Fibroblasts; Humans; Keloid; ortho-Aminobenzoates; S | 1995 |
Nodular scleroderma: focally increased tenascin expression differing from that in the surrounding scleroderma skin.
Topics: Adult; Biopsy; Cell Adhesion Molecules, Neuronal; Diagnosis, Differential; Extracellular Matrix Prot | 1995 |
Silicone gel sheeting in scar therapy.
Topics: Bandages; Chronic Disease; Cicatrix, Hypertrophic; Dermabrasion; Dermatitis, Irritant; Follow-Up Stu | 1995 |
Corneal keloid: aetiology and management in Lowe's syndrome.
Topics: Adolescent; Corneal Diseases; Humans; Keloid; Male; Oculocerebrorenal Syndrome | 1995 |
Silicone gel sheeting for the prevention and management of evolving hypertrophic and keloid scars.
Topics: Adult; Aged; Aged, 80 and over; Bandages; Biopsy, Needle; Cicatrix, Hypertrophic; Evaluation Studies | 1995 |
Mechanical properties of keloids in vivo during treatment with intralesional triamcinolone acetonide.
Topics: Adolescent; Adult; Biomechanical Phenomena; Elasticity; Female; Humans; Injections, Intralesional; K | 1995 |
Hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Diagnosis, Differential; Humans; Incidence; Keloid; Wound Healing | 1995 |
Keloids.
Topics: Humans; Keloid | 1995 |
[The diagnosis and treatment of hypertrophic and keloid scars].
Topics: Acne Vulgaris; Burns; Cicatrix, Hypertrophic; Cryosurgery; Humans; Keloid; Skin | 1994 |
Proliferating activity of dermal fibroblasts in keloids and hypertrophic scars.
Topics: Adolescent; Adult; Aged; Cell Division; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Fib | 1995 |
Symptomatic keloids in two children. Dramatic improvement with silicone cream occlusive dressing.
Topics: Child; Child, Preschool; Female; Foot Dermatoses; Humans; Keloid; Knee; Leg Dermatoses; Occlusive Dr | 1995 |
Men, earrings, and keloids.
Topics: Beauty Culture; Black or African American; Ear; Humans; Keloid; Male | 1995 |
Ectodermal dysplasia syndrome in siblings with true keloids, stenosis of the esophagus after operations for congenital achalasia and renovascular hypertension due to stenosis of renal artery.
Topics: Adult; Ectodermal Dysplasia; Esophageal Achalasia; Esophageal Stenosis; Female; Genes, Recessive; Hu | 1995 |
Platelet-derived growth factors-AA and -BB regulate collagen and collagenase gene expression differentially in human fibroblasts.
Topics: Becaplermin; Cells, Cultured; Collagen; Collagenases; Dose-Response Relationship, Drug; Fibroblasts; | 1995 |
[Results of cryosurgery in 394 patients with hypertrophic scars and keloids].
Topics: Adolescent; Adult; Child; Cicatrix, Hypertrophic; Combined Modality Therapy; Cryosurgery; Female; Fo | 1995 |
Acidic and basic fibroblast growth factors down-regulate collagen gene expression in keloid fibroblasts.
Topics: Collagen; Dose-Response Relationship, Drug; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; | 1993 |
Differential expression of factor XIIIa and CD34 in cutaneous mesenchymal tumors.
Topics: Antigens, CD; Antigens, CD34; Dendritic Cells; Fibroma; Fibrosarcoma; Humans; Keloid; Skin Neoplasms | 1993 |
Keloid formation after surgery for release of polysyndactyly of the feet in a child.
Topics: Female; Humans; Infant; Keloid; Postoperative Complications; Surgical Flaps; Syndactyly; Toes | 1995 |
Association between keloids and Dupuytren's disease: case report.
Topics: Dupuytren Contracture; Humans; Keloid; Male; Middle Aged | 1995 |
Keloids of the breast: mammographic findings.
Topics: Adult; Breast Diseases; Female; Humans; Keloid; Mammaplasty; Mammography | 1995 |
Oncostatin M stimulates collagen and glycosaminoglycan production by cultured normal dermal fibroblasts: insensitivity of sclerodermal and keloidal fibroblasts.
Topics: Adult; Aged; Blotting, Western; Cells, Cultured; Collagen; Female; Fibroblasts; Glycosaminoglycans; | 1995 |
Dermatography as an adjunctive treatment for cleft lip and palate patients.
Topics: Carbon; Cicatrix; Cicatrix, Hypertrophic; Cleft Lip; Cleft Palate; Esthetics; Ferric Compounds; Ferr | 1995 |
Ear lobe keloids, surgical excision followed by radiation therapy: a 10-year experience.
Topics: Adult; Aged; Ear, External; Female; Humans; Keloid; Male; Middle Aged; Retrospective Studies; Treatm | 1994 |
Inhibition of human keloid fibroblast growth by isotretinoin and triamcinolone acetonide in vitro.
Topics: Cell Count; Cell Division; Cell Survival; Cells, Cultured; Fibroblasts; Humans; Isotretinoin; Keloid | 1994 |
Penile oedema induced by continuous condom catheter use and mimicking keloid scar.
Topics: Adult; Diagnosis, Differential; Edema; Humans; Keloid; Male; Penile Diseases; Urethral Diseases; Uri | 1994 |
Complications in otoplastic surgery and their treatment.
Topics: Ear Deformities, Acquired; Ear, External; Hematoma; Humans; Keloid; Necrosis; Pain, Postoperative; P | 1994 |
Hypertrophic and keloid scars.
Topics: Cicatrix, Hypertrophic; Gels; Humans; Keloid; Silicones | 1995 |
Histomorphologic changes in keloids treated with Kenacort.
Topics: Adolescent; Adult; Burns; Child; Female; Fibroblasts; Humans; Keloid; Male; Microscopy, Electron; Mi | 1995 |
Effects of various growth factors and histamine on cultured keloid fibroblasts.
Topics: Cell Division; Cells, Cultured; Collagen; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor | 1995 |
A case of corneal keloid: clinical, surgical, pathological, and ultrastructural characteristics.
Topics: Aged; Corneal Diseases; Humans; Keloid; Male; Microscopy, Electron | 1994 |
Elevated levels of PDGF alpha receptors in keloid fibroblasts contribute to an enhanced response to PDGF.
Topics: Adolescent; Adult; Blotting, Western; Chemotaxis; DNA; Epidermal Growth Factor; Female; Fibroblast G | 1994 |
[Presternal atheroma and its surgical treatment].
Topics: Adult; Cicatrix; Epidermal Cyst; Female; Humans; Hypertrophy; Keloid; Postoperative Complications; R | 1994 |
Effects of x-irradiation on survival and extracellular matrix gene expression of cultured keloid fibroblasts.
Topics: Actins; Adult; Cell Survival; Cells, Cultured; Extracellular Matrix; Female; Fibroblasts; Fibronecti | 1994 |
Keloidal Kaposi's sarcoma: report of three patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Humans; Keloid; Male; Sarcoma, Kaposi; Skin; Skin Neoplas | 1994 |
Dubowitz syndrome with keloidal lesions.
Topics: Abnormalities, Multiple; Child; Dermatitis, Atopic; Facial Expression; Growth Disorders; Humans; Kel | 1994 |
The protruding scars: keloids and hypertrophic diagnosis and treatment with silicon-gel-sheeting.
Topics: Adolescent; Adult; Bandages; Burns; Child; Child, Preschool; Cicatrix; Cryosurgery; Diagnosis, Diffe | 1994 |
Modulation of collagen synthesis by transforming growth factor-beta in keloid and hypertrophic scar fibroblasts.
Topics: Antibodies; Cells, Cultured; Cicatrix, Hypertrophic; Collagen; Fibroblasts; Humans; In Vitro Techniq | 1994 |
The molecular biology of fibroproliferative disorders of the skin: potential cytokine therapeutics.
Topics: Animals; Antibodies; Cells, Cultured; Cicatrix, Hypertrophic; Collagen; Extracellular Matrix; Fibrob | 1994 |
Thallium-201 uptake in keloid tissue masquerading as a pulmonary neoplasm.
Topics: Diagnosis, Differential; Humans; Keloid; Lung Neoplasms; Male; Middle Aged; Myocardial Ischemia; Rad | 1994 |
Silicone use in keloids.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Humans; Keloid; Silicones | 1994 |
Morphological and immunochemical differences between keloid and hypertrophic scar.
Topics: Actins; Adolescent; Adult; Child; Cicatrix, Hypertrophic; Collagen; Fibroblasts; Humans; Keloid; Mic | 1994 |
Keloids treated with excision followed by radiation therapy.
Topics: Adolescent; Adult; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Keloid; Male; Radio | 1994 |
[Keloid of the external ear].
Topics: Adolescent; Child; Ear, External; Female; Follow-Up Studies; Humans; Keloid; Longitudinal Studies; M | 1994 |
Intralesional steroid injection following keloid surgery.
Topics: Anesthesia, Dental; Anesthesia, Local; Humans; Injections, Intralesional; Keloid; Steroids; Syringes | 1994 |
Linear keloids resulting from abuse of anabolic androgenic steroid drugs.
Topics: Anabolic Agents; Doping in Sports; Humans; Keloid | 1994 |
[Complications of marrow harvesting for transplantation].
Topics: Adolescent; Adult; Age Factors; Anesthesia; Bone Marrow Transplantation; Fever; Humans; Hypotension; | 1994 |
[Cultivation of cicatricial fibroblasts and kinetics of growth].
Topics: Adult; Cell Division; Cells, Cultured; Cicatrix, Hypertrophic; Female; Fibroblasts; Humans; Keloid; | 1993 |
Contributions of electron microscopy to the study of the hypertrophic scar and related lesions.
Topics: Animals; Cicatrix, Hypertrophic; Collagen; Fibroblasts; Granulation Tissue; Humans; Keloid; Microcir | 1993 |
[Cicatricial keloids after Waterhouse-Friderichsen syndrome].
Topics: Cicatrix, Hypertrophic; Follow-Up Studies; Hemorrhage; Humans; Infant; Keloid; Male; Necrosis; Skin; | 1994 |
[Simultaneous occurrence of extra-abdominal fibromatosis and post-traumatic keloid].
Topics: Adult; Biopsy; Cicatrix, Hypertrophic; Colectomy; Collagen; Connective Tissue; Fibromatosis, Abdomin | 1994 |
Discrete keloids in a lightning strike.
Topics: Adult; Burns; Humans; Keloid; Lightning Injuries; Male | 1994 |
[Plastic operations in defects and deformities of the perioral area].
Topics: Adult; Burns, Chemical; Disability Evaluation; Facial Injuries; Humans; Keloid; Male; Middle Aged; M | 1994 |
[Treatment of keloids and hypertrophic scars. Pilot study with intralesional Lipotalon injections].
Topics: Adolescent; Adult; Cicatrix; Dexamethasone; Drug Carriers; Female; Humans; Hypertrophy; Injections, | 1994 |
Intralesional interferon alpha-2b has no effect in the treatment of keloids.
Topics: Adolescent; Adult; Female; Humans; Injections, Intralesional; Interferon alpha-2; Interferon-alpha; | 1994 |
Ultrastructural study of a corneal keloid.
Topics: Aged; Cornea; Corneal Diseases; Humans; Keloid; Male; Microscopy, Electron | 1993 |
Analysis of collagen composition in acne keloids.
Topics: Acne Vulgaris; Biopsy; Cell Division; Cells, Cultured; Collagen; Fibroblasts; Humans; Keloid; Procol | 1993 |
Decorin, versican, and biglycan gene expression by keloid and normal dermal fibroblasts: differential regulation by basic fibroblast growth factor.
Topics: Biglycan; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Collagen; Decorin; Extracellular Matri | 1993 |
[Heart failure due to severe myocardial calcification--a rare complication after irradiation on the chest wall].
Topics: Adult; Calcinosis; Cardiomyopathies; Cobalt Radioisotopes; Female; Heart Failure; Heart Valve Prosth | 1993 |
Sternal keloids: successful treatment employing surgery and adjunctive radiation.
Topics: Adolescent; Adult; Aged; Combined Modality Therapy; Female; Humans; Keloid; Male; Middle Aged; Skin | 1993 |
[Cheloid nodule of the free edge of the eyelid].
Topics: Aged; Aged, 80 and over; Cicatrix, Hypertrophic; Eyelids; Female; Humans; Keloid | 1993 |
Treatment of congenital elevation of the scapula. 10 (2-18) year follow-up of 37 cases of Sprengel's deformity.
Topics: Adolescent; Child; Child, Preschool; Follow-Up Studies; Humans; Keloid; Postoperative Complications; | 1993 |
Dermatomyofibroma: additional observations on a distinctive cutaneous myofibroblastic tumour with emphasis on differential diagnosis.
Topics: Actins; Adolescent; Adult; Diagnosis, Differential; Female; Fibrosarcoma; Humans; Immunohistochemist | 1993 |
Differentiation of keloid and hypertrophic scar; correlation of the water proton relaxation times with the duration of the scar.
Topics: Adult; Cicatrix, Hypertrophic; Collagen; Humans; Keloid; Magnetic Resonance Spectroscopy; Protons; R | 1993 |
Exuberant keloidal formation.
Topics: Adult; Combined Modality Therapy; Female; Humans; Injections, Intralesional; Keloid; Triamcinolone A | 1993 |
Plugging the vascular leak.
Topics: Follow-Up Studies; Humans; Keloid; Laser Therapy; Sclerotherapy; Thigh; Treatment Outcome; Ultrasono | 1993 |
Topical silicone gel sheeting in the treatment of hypertrophic scars and keloids. A dermatologic experience.
Topics: Administration, Topical; Adolescent; Adult; Cicatrix, Hypertrophic; Female; Gels; Humans; Keloid; Ma | 1993 |
Regulation of collagen gene expression in keloids and hypertrophic scars.
Topics: Blotting, Northern; Cells, Cultured; Cicatrix, Hypertrophic; Collagen; Fibroblasts; Gene Expression; | 1993 |
Historical notes on the use of pressure in the treatment of hypertrophic scars or keloids.
Topics: Burns; Cicatrix, Hypertrophic; Europe; History, 16th Century; History, 18th Century; History, 19th C | 1993 |
[Radiotherapy in scar-induced keloid].
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Humans; Keloid; Male; | 1993 |
Scabies keloid.
Topics: Female; Humans; Keloid; Scabies | 1993 |
The treatment of 783 keloid scars by iridium 192 interstitial irradiation after surgical excision.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brachytherapy; Child; Child, Preschool; Combined Modalit | 1993 |
Keloid of the penis after circumcision.
Topics: Child; Circumcision, Male; Humans; Keloid; Male; Penile Diseases; Pruritus; Time Factors; Triamcinol | 1993 |
Use of cryotherapy in the treatment of keloids.
Topics: Adolescent; Adult; Atrophy; Child; Cryosurgery; Female; Follow-Up Studies; Humans; Keloid; Male; Pig | 1993 |
[Treatment of keloids of the ear lobe].
Topics: Combined Modality Therapy; Ear, External; Humans; Keloid; Recurrence | 1995 |
Laser treatment of tattoos in darkly pigmented patients: efficacy and side effects.
Topics: Adult; Aluminum Oxide; Aluminum Silicates; Black People; Cicatrix; Ethiopia; Female; Follow-Up Studi | 1996 |
Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders.
Topics: Adolescent; Adult; Child; Connective Tissue Growth Factor; Fibrosis; Gene Expression; Growth Substan | 1996 |
Elevated levels of plasminogen activator inhibitor-1 may account for the altered fibrinolysis by keloid fibroblasts.
Topics: Fibrin; Fibrinolysis; Fibroblasts; Humans; Keloid; Plasminogen Activator Inhibitor 1; RNA, Messenger | 1996 |
Keloid associated with hypertension.
Topics: Adult; Black People; Case-Control Studies; Humans; Hypertension; Keloid; Male; Risk Factors; White P | 1996 |
Increased proliferation in keloid fibroblasts wounded in vitro.
Topics: Autoradiography; Cell Count; Cell Division; Cells, Cultured; Fibroblasts; Humans; Keloid; Thymidine; | 1996 |
Heterogeneity in radiosensitivity of human diploid fibroblasts from keloids and normal skins.
Topics: Aged; Cell Division; Cells, Cultured; Diploidy; Female; Fibroblasts; Humans; Keloid; Male; Middle Ag | 1996 |
[Pierced ears].
Topics: Beauty Culture; Dermatitis, Contact; Ear Diseases; Ear, External; Humans; Infections; Keloid; Punctu | 1996 |
Effects of a water-impermeable, non-silicone-based occlusive dressing on keloids.
Topics: Adolescent; Adult; Aged; Equipment Design; Erythema; Female; Folliculitis; Follow-Up Studies; Humans | 1996 |
Topical silastic gel sheeting for treating and controlling hypertrophic and keloid scars: case study.
Topics: Adult; Burns; Cicatrix, Hypertrophic; Diagnosis, Differential; Gels; Humans; Keloid; Male; Occlusive | 1995 |
[Histomorphology research of keloid in different regions].
Topics: Adolescent; Adult; Female; Humans; Keloid; Male; Middle Aged | 1995 |
Rubinstein-Taybi syndrome with multiple flamboyant keloids.
Topics: Adult; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 1 | 1996 |
Keloidal basal cell carcinoma. A new clinicopathological variant of basal cell carcinoma.
Topics: Aged; Carcinoma, Basal Cell; Facial Neoplasms; Female; Humans; Keloid; Skin Neoplasms | 1996 |
Role of growth factors in scar contraction: an in vitro analysis.
Topics: Cicatrix; Culture Techniques; Fibroblasts; Humans; Keloid; Transforming Growth Factor beta | 1996 |
A case of FG syndrome with gingival hyperplasia and keloids.
Topics: Abnormalities, Multiple; Child; Gingival Hyperplasia; Humans; Keloid; Male; Syndrome | 1995 |
[A study of human keloid with electron spin resonance].
Topics: Connective Tissue; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Keloid; Oxygen | 1996 |
Keloid at the venipuncture site.
Topics: Ampicillin; Catheterization, Peripheral; Catheters, Indwelling; Cefotaxime; Child; Cicatrix, Hypertr | 1995 |
Measurement of radiation-induced DNA double-strand breaks in human diploid fibroblasts from keloid and normal skin by single-cell gel electrophoresis.
Topics: Cells, Cultured; Diploidy; DNA Damage; DNA Repair; Electrophoresis, Polyacrylamide Gel; Fibroblasts; | 1996 |
The effect of TGF-beta on keloid fibroblast proliferation and collagen synthesis.
Topics: Cell Division; Cells, Cultured; Collagen; Fibroblasts; Humans; Keloid; Transforming Growth Factor be | 1996 |
Downregulation of inducible nitric oxide synthase expression in keloids.
Topics: Base Sequence; Down-Regulation; Humans; Keloid; Molecular Sequence Data; Nitric Oxide Synthase | 1996 |
DNA binding proteins from keloid fibroblasts form unique complexes with the human fibronectin promoter.
Topics: Adolescent; Adult; Base Sequence; Binding Sites; Blood; Cells, Cultured; Child; Child, Preschool; Ci | 1996 |
Mast cells and myofibroblasts in keloid: a light microscopic, immunohistochemical and ultrastructural study.
Topics: Actin Cytoskeleton; Adult; Cell Degranulation; Cell Membrane; Collagen; Cytoplasm; Cytoplasmic Granu | 1995 |
Treatment of earlobe keloids with surgery plus adjuvant intralesional verapamil and pressure earrings.
Topics: Adolescent; Adult; Calcium Channel Blockers; Child; Ear, External; Female; Humans; Keloid; Male; Mid | 1996 |
Silicone cream occlusive dressing--a novel noninvasive regimen in the treatment of keloid.
Topics: Adult; Dosage Forms; Female; Humans; Keloid; Male; Middle Aged; Occlusive Dressings; Silicones | 1996 |
Keloid of the penis after circumcision.
Topics: Child; Circumcision, Male; Humans; Keloid; Male; Penile Diseases | 1996 |
Otolaryngologist's role in transtracheal oxygen therapy: the minitrach procedure.
Topics: Female; Humans; Keloid; Male; Otolaryngology; Oxygen Inhalation Therapy; Postoperative Care; Role; T | 1996 |
Body contouring. Introduction.
Topics: Abdomen; Adult; Aged; Chin; Female; Humans; Keloid; Lipectomy; Mammaplasty; Middle Aged; Surgery, Pl | 1996 |
Apoptosis, necrosis, and proliferation: possible implications in the etiology of keloids.
Topics: Acridine Orange; Apoptosis; Cell Division; Humans; In Situ Hybridization; Keloid; Necrosis; Prolifer | 1996 |
[Treatment of keloids (review of the literature, therapeutic suggestions)].
Topics: Administration, Topical; Cicatrix, Hypertrophic; Cryotherapy; Female; Humans; Hydrocortisone; Keloid | 1996 |
Aetiology and management of hypertrophic scars and keloids.
Topics: Administration, Topical; Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Glucocorticoids; Humans; | 1996 |
Co-ordinate induction of collagen type I and biglycan expression in keloids.
Topics: Biglycan; Blotting, Northern; Collagen; Extracellular Matrix Proteins; Gene Expression; Humans; Immu | 1996 |
Functional analyses of the stratum corneum in scars. Sequential studies after injury and comparison among keloids, hypertrophic scars, and atrophic scars.
Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Atrophy; Body Water; Cell Division; Child; Chil | 1996 |
Signaling networks in barrier homeostasis. The mystery widens.
Topics: Cicatrix; Cicatrix, Hypertrophic; Collagen; Cytokines; Epidermis; Extracellular Matrix; Fibroblasts; | 1996 |
Keloid formation with the 585-nm pulsed dye laser during isotretinoin treatment.
Topics: Adolescent; Female; Humans; Isotretinoin; Keloid; Keratolytic Agents; Laser Therapy; Lasers | 1997 |
Severe folliculitis with keloid scars induced by wax epilation in adolescents.
Topics: Adolescent; Female; Folliculitis; Hair Removal; Humans; Keloid | 1997 |
Keloid formation in syndactyly release: report of two cases.
Topics: Child; Female; Fingers; Humans; Infant; Keloid; Male; Postoperative Complications; Reoperation; Synd | 1997 |
Keloidlike morphea.
Topics: Female; Humans; Keloid; Middle Aged; Neck; Scleroderma, Localized | 1997 |
[Utilization potential of the CO2-laser in dermal changes].
Topics: Adolescent; Adult; Aged; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Female; Follow-Up Studies; H | 1996 |
Long-standing pigmented keloid of the ears induced by electrical torture.
Topics: Adult; Ear, External; Electric Injuries; Humans; Hyperpigmentation; Keloid; Male; Torture | 1997 |
Serum-free keloid fibroblast cell culture: an in vitro model for the study of aberrant wound healing.
Topics: Cell Division; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Fibroblasts; Humans; Keloi | 1997 |
Facial keloids. A 15-year experience.
Topics: Anti-Inflammatory Agents; Facial Dermatoses; Humans; Keloid; Recurrence; Retrospective Studies; Tria | 1997 |
Silver staining of nucleolar organizer regions in keloid scars.
Topics: Fibroblasts; Humans; Keloid; Nucleolus Organizer Region; Silver Staining | 1997 |
The phospholipid analogue hexadecylphosphocholine (HePC) inhibits proliferation of keloid fibroblasts in vitro and modulates their fibronectin and integrin synthesis.
Topics: Cell Division; Cells, Cultured; Collagen; Extracellular Matrix; Fibroblasts; Fibronectins; Humans; I | 1997 |
Contact reactions to the jellyfish Carybdea marsupialis: observation of 40 cases.
Topics: Adolescent; Adult; Animals; Child; Dermatitis, Irritant; Female; Humans; Italy; Keloid; Male; Marine | 1997 |
Silicone gel sheeting for the management of hypertrophic and keloid scars: the mechanism of its action.
Topics: Blood Proteins; Cicatrix, Hypertrophic; Edema; Exudates and Transudates; Humans; Keloid; Occlusive D | 1997 |
[Normal and pathological cicatrization. Physiopathology and anatomopathology].
Topics: Cicatrix; Cicatrix, Hypertrophic; Keloid | 1997 |
Propiomelanocortin (POMC) gene expression by normal skin and keloid fibroblasts in culture: modulation by cytokines.
Topics: Cells, Cultured; DNA Probes; DNA, Complementary; Epidermal Cells; Fibroblasts; Gene Expression Regul | 1997 |
Treatment of keloid and hypertrophic scars by iontophoretic transdermal delivery of tranilast.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Animals; Child; Cicatrix; | 1997 |
Elevated levels of testosterone receptors in keloid tissue: an experimental investigation.
Topics: Adolescent; Adult; Aged; DNA; Female; Humans; Keloid; Male; Middle Aged; Receptors, Androgen | 1997 |
Suppressive effects of tranilast on the expression of inducible cyclooxygenase (COX2) in interleukin-1beta-stimulated fibroblasts.
Topics: Anti-Allergic Agents; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Fibroblasts | 1997 |
Factors affecting hypertrophic scar development in median sternotomy incisions for congenital cardiac surgery.
Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Cicatrix, Hypertrophi | 1997 |
Keloid excision and recurrence prophylaxis via interdermal interferon-gamma injections.
Topics: Cicatrix, Hypertrophic; Dermatologic Agents; Female; Follow-Up Studies; Humans; Injections, Intrader | 1997 |
Suit for post-operative scar: keloid or burn?
Topics: Burns; Female; Humans; Intraoperative Complications; Keloid; Louisiana; Malpractice | 1996 |
[Treatment of keloid cicatrix at Yaounde General Hospital. Apropos of 47 cases].
Topics: Black People; Cameroon; Cicatrix, Hypertrophic; Humans; Keloid; Radiotherapy Dosage; Suture Techniqu | 1997 |
Keloids: peripheral and central differences in cell morphology and fatty acid compositions of lipids.
Topics: Cell Hypoxia; Chromatography, Thin Layer; Fatty Acids; Fibroblasts; Humans; Keloid; Linoleic Acid; L | 1997 |
The role of suture material in hypertrophic scar formation: Monocryl vs. Vicryl-rapide.
Topics: Abscess; Breast; Cicatrix, Hypertrophic; Dioxanes; Female; Humans; Hypertrophy; Keloid; Mammaplasty; | 1997 |
Silver-stained nucleolar organizer regions in hypertrophic and keloid scars.
Topics: Analysis of Variance; Biomarkers; Cell Division; Cell Nucleus; Cicatrix, Hypertrophic; Collagen; Col | 1997 |
Solitary fibrous tumor of the skin.
Topics: Actins; Adult; Antigens, CD; Antigens, CD34; Antigens, Differentiation, Myelomonocytic; Biomarkers, | 1997 |
Prevalence of acne keloidalis nuchae in football players.
Topics: Acne Keloid; Acne Vulgaris; Adolescent; Adult; Age Factors; Analysis of Variance; Black People; Conf | 1997 |
Major suppression of pro-alpha1(I) type I collagen gene expression in the dermis after keloid excision and immediate intrawound injection of triamcinolone acetonide.
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Biopsy; Collagen; Coloring Age | 1997 |
Recurrence rates of excised keloids treated with postoperative triamcinolone acetonide injections or interferon alfa-2b injections.
Topics: Adolescent; Adult; Chemotherapy, Adjuvant; Child; Combined Modality Therapy; Female; Follow-Up Studi | 1997 |
Exposure of fibroblasts derived from keloid patients to low-energy electromagnetic fields: preferential inhibition of cell proliferation, collagen synthesis, and transforming growth factor beta expression in keloid fibroblasts in vitro.
Topics: Adolescent; Adult; Blotting, Northern; Cell Division; Collagen; Electromagnetic Fields; Female; Fibr | 1997 |
Practice tip. Reducing hypertrophic or keloid scars.
Topics: Cicatrix; Humans; Injections, Intralesional; Keloid; Radiotherapy; Steroids | 1997 |
Otoplasty: a combined approach to different structures of the auricle.
Topics: Adolescent; Adult; Bandages; Child; Child, Preschool; Cicatrix; Dermatologic Surgical Procedures; Ea | 1997 |
Two patients with penile keloids: a review of the literature.
Topics: Adolescent; Anti-Inflammatory Agents; Circumcision, Male; Humans; Injections, Intralesional; Keloid; | 1997 |
Artificial skin equivalent differentiation depends on fibroblast donor site: use of eyelid fibroblasts.
Topics: Adolescent; Adult; Aged; Cell Differentiation; Cells, Cultured; Epidermal Cells; Eyelids; Female; Fi | 1998 |
Earlobe reconstruction using a subcutaneous island pedicle flap after resection of "earlobe keloid".
Topics: Adult; Ear, External; Female; Humans; Keloid; Male; Surgical Flaps | 1998 |
Laser treatment of hypertrophic scars and keloids.
Topics: Cicatrix, Hypertrophic; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Laser Therapy; M | 1998 |
Combined approach to the treatment of earlobe keloids.
Topics: Adolescent; Anti-Inflammatory Agents; Bandages; Combined Modality Therapy; Ear Diseases; Ear, Extern | 1998 |
Keloid fibroblasts from a Caucasian patient: are there differences in growth kinetics?
Topics: Black People; Fibroblasts; Humans; Keloid; Male; White People | 1998 |
Postoperative interstitial radiotherapy of keloids by iridium 192: a retrospective study of 46 treated scars.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Brachytherapy; Child; Female; Follow-Up Studies; Humans; | 1997 |
Impairment in the fatty acid composition of keloids.
Topics: Black People; Confidence Intervals; Dietary Fats, Unsaturated; Fatty Acids; Humans; Keloid; Linoleic | 1997 |
Scars. Can they be minimised?
Topics: Ambulatory Surgical Procedures; Bandages; Cicatrix; Cicatrix, Hypertrophic; Dermatologic Surgical Pr | 1998 |
An in vivo model of human proliferative scar.
Topics: Animals; Cell Count; Cicatrix, Hypertrophic; Dermatologic Surgical Procedures; Disease Models, Anima | 1998 |
Keloidal dermatofibroma: report of 10 cases of a new variant.
Topics: Adolescent; Adult; Biomarkers; Female; Follow-Up Studies; Histiocytes; Histiocytoma, Benign Fibrous; | 1998 |
Tamoxifen downregulates TGF-beta production in keloid fibroblasts.
Topics: Cell Culture Techniques; Down-Regulation; Estrogen Antagonists; Fibroblasts; Humans; Keloid; Lucifer | 1998 |
Cultured epithelial autografts in the treatment of extensive recalcitrant keloids.
Topics: Adult; Culture Techniques; Epithelial Cells; Humans; Keloid; Male | 1998 |
[Treatment of keloid with intralesional bleomycin].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Bleomycin; Female; Humans; | 1996 |
The expression of alpha 2 beta 1 integrin and alpha smooth muscle actin in fibroblasts grown on collagen.
Topics: Actins; Adult; Cells, Cultured; Collagen; Fibroblasts; Fluorescent Antibody Technique; Humans; Integ | 1998 |
Recurrent cutaneous leiomyosarcoma.
Topics: Adult; Buttocks; Diagnostic Errors; Female; Histiocytoma, Benign Fibrous; Humans; Keloid; Leiomyosar | 1998 |
An inexpensive self fabricated pressure clip for the ear lobe.
Topics: Ear, External; Equipment Design; Humans; Keloid; Plastic Surgery Procedures; Polymethyl Methacrylate | 1998 |
Regression in keloid scar by intralesional injection of papaya milk.
Topics: Fruit; Humans; Injections, Intralesional; Keloid | 1998 |
Linear focal elastosis: Keloidal repair of striae distensae.
Topics: Adult; Connective Tissue Diseases; Elastic Tissue; Humans; Keloid; Male; Skin Diseases | 1998 |
A new hereditary conjunctivo-corneal dystrophy associated with dermal keloid formation. Report of a family.
Topics: Adolescent; Adult; Conjunctival Diseases; Corneal Dystrophies, Hereditary; Female; Humans; Keloid; M | 1998 |
Analysis of p53 gene mutations in keloids using polymerase chain reaction-based single-strand conformational polymorphism and DNA sequencing.
Topics: Adult; Apoptosis; Arginine; Cell Death; Cell Division; Cells, Cultured; Codon; Cytosine; Exons; Fibr | 1998 |
p53 in dermatology.
Topics: Animals; Carcinoma, Squamous Cell; DNA Damage; DNA Repair; Extracellular Matrix; Fibroblasts; Furoco | 1998 |
Altered posttranslational modifications of collagen in keloid.
Topics: Adult; Amino Acids; Collagen; Cross-Linking Reagents; Desmosine; Dipeptides; Histidine; Humans; Hydr | 1998 |
Keloids and end-stage renal disease.
Topics: Black People; Humans; Keloid; Kidney Failure, Chronic | 1998 |
Distinct patterns of collagen gene expression are seen in normal and keloid fibroblasts grown in three-dimensional culture.
Topics: Adult; Aged; Blotting, Northern; Cells, Cultured; Child, Preschool; Cicatrix; Cicatrix, Hypertrophic | 1998 |
Acne keloidalis is lichen simplex chronicus with fibrotic keloidal scarring.
Topics: Acne Keloid; Diagnosis, Differential; Fibrosis; Humans; Keloid; Neck; Neurodermatitis | 1998 |
Preventing hypertrophic scarring and keloids.
Topics: Bandages; Humans; Keloid; Skin Care; Wounds and Injuries | 1998 |
Mast cells in pathological and surgical scars.
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; Mast | 1998 |
Photorefractive keratectomy in African Americans including those with known dermatologic keloid formation.
Topics: Adult; Black People; California; Contraindications; Cornea; Female; Follow-Up Studies; Humans; Keloi | 1998 |
Pretibial myxoedema presenting as a scar infiltrate.
Topics: Adult; Biopsy; Cicatrix, Hypertrophic; Humans; Hyperthyroidism; Keloid; Leg Dermatoses; Leg Injuries | 1998 |
The effectiveness of a new method for assessing induration.
Topics: Female; Hardness; Humans; Keloid; Male; Predictive Value of Tests; Skin Diseases | 1998 |
Carbon dioxide laser ablation associated with interferon alfa-2b injections reduces the recurrence of keloids.
Topics: Antineoplastic Agents; Carbon Dioxide; Female; Humans; Injections, Subcutaneous; Interferon-alpha; K | 1998 |
Involution of keloid implants in athymic mice treated with pirfenidone or with triamcinolone.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cell Transplantation; Electrop | 1998 |
[The long-term anterior chest median wound keloid after the cardiac surgery].
Topics: Adolescent; Adult; Aged; Cardiac Surgical Procedures; Female; Heart Diseases; Humans; Keloid; Male; | 1998 |
[Dilemmas in cicatrization].
Topics: Cicatrix; Humans; Keloid; Nutrition Disorders; Skin; Skin Ulcer; Wound Healing | 1998 |
[Clinical and morphological evaluation of laser therapy effectiveness for keloid skin scars in children].
Topics: Child; Follow-Up Studies; Humans; Keloid; Laser Therapy; Retrospective Studies; Skin; Treatment Outc | 1999 |
Temporary henna tattoo with permanent scarification.
Topics: Child, Preschool; Cicatrix; Coloring Agents; Dermatitis, Contact; Humans; Keloid; Male; Naphthoquino | 1999 |
Overexpression of insulin-like growth factor-1 (IGF-I) receptor and the invasiveness of cultured keloid fibroblasts.
Topics: Adolescent; Adult; Animals; Cell Division; Cell Movement; Cells, Cultured; DNA, Complementary; Femal | 1999 |
UV-A1 for keloid.
Topics: Adult; Humans; Keloid; Male; Remission Induction; Ultraviolet Therapy | 1999 |
TGF-beta2 activates proliferative scar fibroblasts.
Topics: Antibodies; Burns; Cell Division; Cells, Cultured; Cicatrix; Fibroblasts; Humans; Keloid; Reference | 1999 |
Hypertrophic scars, keloids, and laryngotracheal stenosis.
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Laryngostenosis | 1999 |
Keloid after circumcision.
Topics: Circumcision, Male; Humans; Keloid; Male; Penile Diseases | 1999 |
Pain-free intralesional injection of triamcinolone for the treatment of keloid.
Topics: Glucocorticoids; Humans; Injections, Intralesional; Keloid; Middle Aged; Needles; Pain; Pain Measure | 1999 |
Keloid formation induced by isotretinoin therapy.
Topics: Acne Vulgaris; Adolescent; Humans; Isotretinoin; Keloid; Keratolytic Agents; Male | 1999 |
Differential regulation of PAI-1 gene expression in human fibroblasts predisposed to a fibrotic phenotype.
Topics: Adult; Cell Adhesion; Cells, Cultured; Dermis; Female; Fibroblasts; Fibrosis; Gene Expression Regula | 1999 |
[The indications for and results of HDR afterloading therapy in diseases of the skin and mucosa with standardized surface applicators (the Leipzig applicator)].
Topics: Adult; Aged; Brachytherapy; Female; Humans; Keloid; Male; Middle Aged; Palliative Care; Paronychia; | 1999 |
Relief of pain and itch associated with keloids on treatment with oxpentifylline.
Topics: Adult; Aged; Dermatologic Agents; Female; Humans; Keloid; Male; Pain; Pentoxifylline; Pruritus | 1999 |
The effect of the anti-allergic agent avil on abnormal scar fibroblasts.
Topics: Adolescent; Adult; Anti-Allergic Agents; Cell Division; Cells, Cultured; Child; Cicatrix, Hypertroph | 1999 |
Hypoxia upregulates VEGF production in keloid fibroblasts.
Topics: Endothelial Growth Factors; Extracellular Matrix; Humans; Hypoxia; Keloid; Lymphokines; Up-Regulatio | 1999 |
Recurrent plantar keloid.
Topics: Adult; Female; Foot Diseases; Humans; Keloid; Recurrence; Treatment Outcome | 1999 |
[Nodules of the external ear].
Topics: Angiolymphoid Hyperplasia with Eosinophilia; Calcinosis; Carcinoma, Basal Cell; Carcinoma, Squamous | 1999 |
Increased expression of tenascin C by keloids in vivo and in vitro.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Cells, Cultured; Collagen; Extracellular Matrix | 1999 |
[Determination of intracellular calcium ions in fibroblasts of contractured scar].
Topics: Biological Transport, Active; Calcium; Cells, Cultured; Cicatrix, Hypertrophic; Contracture; Fibrobl | 1998 |
[Observation of cicatricial fibroblasts in culture and its biological properties].
Topics: Adolescent; Adult; Burns; Cell Division; Cells, Cultured; Cicatrix, Hypertrophic; DNA; Female; Fibro | 1998 |
[The responses of fibroblasts from three parts of keloids and normal skin to interleukin-1 beta and interleukin-6].
Topics: Adult; Cell Division; Cells, Cultured; Female; Fibroblasts; Humans; Interleukin-1; Interleukin-6; Ke | 1998 |
[Study on in situ expression of type I and III procollagen mRNAs in different parts of keloid and normal skin].
Topics: Adult; Female; Fibroblasts; Humans; Keloid; Male; Procollagen; Random Allocation; RNA, Messenger; Sk | 1998 |
[Comparative study on biological characteristics and ultrastructure of the fibroblasts derived from normal skin, hypertrophic scar and keloidin in vitro culture].
Topics: Adolescent; Adult; Cell Count; Cell Division; Cells, Cultured; Child; Child, Preschool; Cicatrix, Hy | 1998 |
Effect of TGF-beta2 on proliferative scar fibroblast cell kinetics.
Topics: Animals; Cell Division; Cells, Cultured; Cicatrix, Hypertrophic; Fibroblasts; Humans; Keloid; Protei | 1999 |
Expression of transforming growth factor beta 1, 2, and 3 proteins in keloids.
Topics: Adolescent; Adult; Blotting, Western; Fibroblasts; Humans; Keloid; Middle Aged; Protein Isoforms; Sk | 1999 |
Keloids have continuous high metabolic activity.
Topics: Adenosine Triphosphate; Adolescent; Adult; Cell Count; Chromatography, High Pressure Liquid; Cicatri | 1999 |
Bullous keloid: a distinct entity?
Topics: Adult; Aortic Valve; Heart Valve Diseases; Humans; Keloid; Male; Postoperative Complications; Rheuma | 1999 |
Expression of type XVI collagen in human skin fibroblasts: enhanced expression in fibrotic skin diseases.
Topics: Adolescent; Adult; Collagen; Female; Fibroblasts; Fluorescent Antibody Technique; Humans; Keloid; Ma | 1999 |
Growth of keloid-producing fibroblasts in commercially available serum-free media.
Topics: Cell Division; Cell Survival; Culture Media, Serum-Free; Fibroblast Growth Factors; Fibroblasts; Hum | 1999 |
Complete excision with staged reconstruction in the treatment of earlobe keloid after ear piercing.
Topics: Cosmetic Techniques; Ear, External; Female; Humans; Keloid; Middle Aged; Punctures | 1999 |
Keloids and hypertrophic scars: results with intraoperative and serial postoperative corticosteroid injection therapy.
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Cicat | 1999 |
[Hypertrophic scars and keloids: which therapeutic options today?].
Topics: Adult; Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Follow-U | 1999 |
Unusual complications of circumcision.
Topics: Circumcision, Male; Humans; Keloid; Male; Penile Diseases; Postoperative Complications; Reoperation | 1999 |
Eruptive paraneoplastic keloids.
Topics: Abdominal Muscles; Adenocarcinoma; Aged; Biopsy, Needle; Endometrial Neoplasms; Female; Humans; Kelo | 1999 |
A study of the spectrum of skin disease occurring in a black population in south-east London.
Topics: Acne Vulgaris; Acrodermatitis; Adult; Black or African American; Black People; Child; Cohort Studies | 1999 |
Scarring in papillary carcinoma of the thyroid: report of two new cases with exuberant nodular fasciitis-like stroma.
Topics: Adult; Aged; Carcinoma, Papillary; Cell Transformation, Neoplastic; Female; Humans; Immunoenzyme Tec | 1999 |
Non-invasive monitoring of the mechanical properties of keloids during cryosurgery.
Topics: Adult; Cryosurgery; Follow-Up Studies; Humans; Keloid; Male; Minimally Invasive Surgical Procedures; | 1999 |
Downregulation of apoptosis-related genes in keloid tissues.
Topics: Adolescent; Adult; Apoptosis; Apoptosis Regulatory Proteins; Caenorhabditis elegans Proteins; Down-R | 1999 |
Fraternal keloid.
Topics: Adolescent; Chickenpox; Child; Ear, External; Follow-Up Studies; Humans; Keloid; Male; Nuclear Famil | 1999 |
Dressing to facilitate early radiotherapy after excision of keloid.
Topics: Bandages; Combined Modality Therapy; Humans; Keloid; Time Factors | 1999 |
Radio frequency radiation of millimeter wave length: potential occupational safety issues relating to surface heating.
Topics: Accidents, Occupational; Cicatrix; Eye; Hot Temperature; Humans; Keloid; Microwaves; Occupational Ex | 2000 |
Biochemical and dynamic studies of collagen from human normal skin and keloid tissue.
Topics: Collagen; Electrophoresis, Polyacrylamide Gel; Glycosaminoglycans; Hot Temperature; Humans; Keloid; | 1999 |
Expression of Bcl-2, p53, c-jun and c-fos protooncogenes in keloids and hypertrophic scars.
Topics: Apoptosis; Cicatrix, Hypertrophic; Gene Expression; Genes, bcl-2; Genes, fos; Genes, jun; Genes, p53 | 1999 |
Keloids: time to dispel the myths?
Topics: Asian People; Black People; Dermatologic Agents; Gonadal Steroid Hormones; Humans; Isotretinoin; Kel | 1999 |
[Compression treatment after burns].
Topics: Adult; Bandages; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Humans; Keloid; Treatment O | 1999 |
Myofibroblast phenotype and apoptosis in keloid and palmar fibroblasts in vitro.
Topics: Apoptosis; Cell Differentiation; Cells, Cultured; Collagen; Fibroblasts; Humans; Keloid; Muscles; Tr | 2000 |
Elevated interleukin-6 expression in keloid fibroblasts.
Topics: Blood Physiological Phenomena; Cells, Cultured; Fibroblasts; Gene Expression; Humans; Interferon-gam | 2000 |
From the literature: intralesional 5-FU in the treatment of hypertrophic scars and keloids: clinical experience.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Injections, Intralesional; Keloid | 2000 |
Enhanced expression of caspase-3 in hypertrophic scars and keloid: induction of caspase-3 and apoptosis in keloid fibroblasts in vitro.
Topics: Adolescent; Adult; Aged; Apoptosis; Caspase 2; Caspase 3; Caspase Inhibitors; Caspases; Child; Child | 2000 |
Reduced hyaluronan in keloid tissue and cultured keloid fibroblasts.
Topics: Adolescent; Adult; Cells, Cultured; Female; Fibroblasts; Humans; Hyaluronic Acid; Hydrocortisone; Ke | 2000 |
[Giant cheloid scars].
Topics: Adult; Cicatrix, Hypertrophic; Female; Humans; Keloid | 2000 |
POMC and fibroblast biology.
Topics: Cells, Cultured; Fibroblasts; Gene Expression Regulation; Humans; Keloid; Keratinocytes; Kinetics; P | 1999 |
[Treatment of keloids and hypertrophic scars with cryotherapy].
Topics: Adult; Cicatrix, Hypertrophic; Cryosurgery; Female; Humans; Keloid; Laser Therapy; Male | 1999 |
The effect of superpulsed carbon dioxide laser energy on keloid and normal dermal fibroblast secretion of growth factors: a serum-free study.
Topics: Cell Division; Cells, Cultured; Culture Media, Serum-Free; Dermis; Enzyme-Linked Immunosorbent Assay | 2000 |
Treatment of extensive sternum keloid scar with surgical removal and immediate reconstruction with skin flaps from a combined mammaplasty.
Topics: Breast; Female; Humans; Keloid; Mammaplasty; Middle Aged; Sternum; Surgical Flaps | 2000 |
Use of keloid skin as an autograft for earlobe reconstruction after excision.
Topics: Adult; Ear, External; Foreign Bodies; Humans; Keloid; Male; Plastic Surgery Procedures; Punctures; S | 2000 |
Results of prophylactic irradiation in patients with resected keloids--a retrospective analysis.
Topics: Adult; Brachytherapy; Combined Modality Therapy; Female; Humans; Keloid; Male; Prognosis; Radiothera | 2000 |
A technique to avoid atrophy in combined intralesional excision and steroid injection for keloids.
Topics: Administration, Topical; Anti-Inflammatory Agents; Atrophy; Glucocorticoids; Humans; Injections, Int | 2000 |
Mathematical modelling of nitric oxide activity in wound healing can explain keloid and hypertrophic scarring.
Topics: Cicatrix, Hypertrophic; Collagen; Humans; Keloid; Models, Biological; Nitric Oxide; Skin; Wound Heal | 2000 |
Insulin-like growth factor-I (IGF-I)/IGF-I receptor axis and increased invasion activity of fibroblasts in keloid.
Topics: Adolescent; Adult; Aged; Antibodies; Cells, Cultured; Child, Preschool; Female; Fibroblasts; Humans; | 2000 |
[Plastic reconstructions in the neck area. Superficial soft tissues of the neck: scar revisions].
Topics: Cicatrix; Cicatrix, Hypertrophic; Contracture; Dermabrasion; Esthetics; Humans; Keloid; Neck; Postop | 2000 |
Effects of silicone gel sheet on the stratum corneum hydration.
Topics: Adult; Aged; Biophysical Phenomena; Biophysics; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male | 2000 |
Varicella causes skin pits and keloids--more reasons for the varicella vaccine.
Topics: Adolescent; Adult; Chickenpox; Cicatrix; Female; Humans; Keloid; Male | 2000 |
Perpendicular suture method for earlobe keloids.
Topics: Ear, External; Female; Humans; Keloid; Male; Sensitivity and Specificity; Surgical Procedures, Opera | 2000 |
Is the reversed fourth dorsal metacarpal flap reliable?
Topics: Cadaver; Dupuytren Contracture; Hand; Humans; Keloid; Male; Surgical Flaps | 2000 |
Preliminary experience with 2-octylcyanoacrylate in a pediatric emergency department.
Topics: Adolescent; Child; Child, Preschool; Cyanoacrylates; Emergency Treatment; Female; Hematoma; Humans; | 2000 |
Keloid-derived fibroblasts are refractory to Fas-mediated apoptosis and neutralization of autocrine transforming growth factor-beta1 can abrogate this resistance.
Topics: Antibodies; Apoptosis; Autocrine Communication; bcl-2-Associated X Protein; bcl-X Protein; Caspases; | 2000 |
Keloids in rural black South Africans. Part 2: dietary fatty acid intake and total phospholipid fatty acid profile in the blood of keloid patients.
Topics: Adolescent; Adult; Arachidonic Acid; Black People; Case-Control Studies; Chromatography, Thin Layer; | 2000 |
Keloids in rural black South Africans. Part 3: a lipid model for the prevention and treatment of keloid formations.
Topics: Apoptosis; Arachidonic Acid; Biopsy; Black People; Case-Control Studies; Cell Division; Cholesterol | 2000 |
[Keloids. 52 cases treated at Ouagadougou].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Black People; Burkina Faso; Combined Modality Therapy; | 2000 |
Keloid fibroblasts resist ceramide-induced apoptosis by overexpression of insulin-like growth factor I receptor.
Topics: Apoptosis; Ceramides; Fibroblasts; Humans; Keloid; Phosphatidylinositol 3-Kinases; Receptor, IGF Typ | 2000 |
Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblasts.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adolescent; Adult; Anti | 2000 |
Static electric field interaction with tissues.
Topics: Biophysical Phenomena; Biophysics; Cicatrix, Hypertrophic; Humans; Keloid; Occlusive Dressings; Sili | 1999 |
Upregulation of HSP47 and collagen type III in the dermal fibrotic disease, keloid.
Topics: Adolescent; Adult; Aged; Collagen; Female; Gene Expression Regulation; Heat-Shock Proteins; HSP47 He | 2001 |
Abnormal balance between proliferation and apoptotic cell death in fibroblasts derived from keloid lesions.
Topics: Adult; Apoptosis; Cell Count; Cell Division; Cells, Cultured; Extracellular Matrix; Female; Fibrobla | 2001 |
A new surgical treatment of keloid: keloid core excision.
Topics: Abdomen; Adolescent; Adult; Ear, External; Face; Female; Genitalia; Humans; Keloid; Male; Plastic Su | 2001 |
Altered expression of keratins during abnormal wound healing in human skin.
Topics: Adolescent; Adult; Biomarkers; Cicatrix, Hypertrophic; Epidermis; Female; Humans; Keloid; Keratins; | 2001 |
Ultrasound assessment of scald scars in Asian children receiving pressure garment therapy.
Topics: Adolescent; Analysis of Variance; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Gr | 2001 |
Bleomycin in the treatment of keloids and hypertrophic scars by multiple needle punctures.
Topics: Adolescent; Adult; Bleomycin; Cicatrix, Hypertrophic; Female; Humans; Keloid; Male; Needles; Punctur | 2001 |
Cutaneous cryptococcosis mimicking keloid.
Topics: Adult; Cryptococcosis; Cryptococcus neoformans; Diagnosis, Differential; Facial Dermatoses; Humans; | 2001 |
[Surgical treatment of Verneuil's disease (hidradenitis suppurativa): 15 cases].
Topics: Abscess; Adult; Chronic Disease; Female; Fistula; Hidradenitis Suppurativa; Humans; Keloid; Male; Mi | 2001 |
Subtotal keloid excision--a preferable preventative regarding recurrence.
Topics: Humans; Keloid; Recurrence; Surgical Procedures, Operative | 2001 |
Investigation of the influence of keloid-derived keratinocytes on fibroblast growth and proliferation in vitro.
Topics: Adolescent; Adult; Cell Communication; Cell Division; Cells, Cultured; Coculture Techniques; Colorim | 2001 |
Noonan syndrome: a case with recurrent keloid formation.
Topics: Child; Humans; Keloid; Male; Noonan Syndrome; Recurrence; Skin Diseases | 2001 |
Clinical, surgical, and histopathologic characteristics of corneal keloid.
Topics: Adolescent; Collagen; Corneal Diseases; Fibroblasts; Humans; Keloid; Keratoplasty, Penetrating; Male | 2001 |
Effect of sucrose on collagen metabolism in keloid, hypertrophic scar, and granulation tissue fibroblast cultures.
Topics: Cicatrix, Hypertrophic; Collagen; Down-Regulation; Granulation Tissue; Humans; Keloid; Peptide Fragm | 2001 |
Radiation therapy for keloids and plantar warts.
Topics: Adolescent; Adult; Aged; Chi-Square Distribution; Child; Child, Preschool; Dose Fractionation, Radia | 2001 |
Differential effects of hexoses and sucrose, and platelet-derived growth factor isoforms on cyclooxygenase-1 and -2 mRNA expression in keloid, hypertrophic scar and granulation tissue fibroblasts.
Topics: Cells, Cultured; Cicatrix, Hypertrophic; Cyclooxygenase 1; Cyclooxygenase 2; Fibroblasts; Granulatio | 2001 |
Treatment of keloid scars with pulsed dye laser and intralesional steroid.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Female; Humans; Keloid; Laser Therapy; Male; Meth | 2000 |
Erythema elevatum diutinum mimicking extensive keloids; quiz 386.
Topics: Dapsone; Diagnosis, Differential; Humans; Keloid; Male; Middle Aged; Skin; Skin Diseases, Vascular | 2001 |
Keloids and hypertrophic scars of Caucasians show distinctive morphologic and immunophenotypic profiles.
Topics: Actins; Adolescent; Adult; Cell Count; Child; Child, Preschool; Cicatrix, Hypertrophic; Desmin; Fema | 2001 |
Aggressive keloid scarring of the Caucasian wrist and palm.
Topics: Adult; Carpal Tunnel Syndrome; Female; Hand Dermatoses; Humans; Keloid; Nerve Compression Syndromes; | 2001 |
Differential expression of transforming growth factor-beta receptors I and II and activation of Smad 3 in keloid fibroblasts.
Topics: Activin Receptors, Type I; Adolescent; DNA-Binding Proteins; Fibroblasts; Humans; Keloid; Middle Age | 2001 |
[Experimental study and preliminary clinical application of bacterial collagenase in catabolizing scars].
Topics: Adolescent; Adult; Animals; Child; Cicatrix, Hypertrophic; Female; Humans; Injections, Intralesional | 1999 |
Ear-lobe keloids: treatment by a protocol of surgical excision and immediate postoperative adjuvant radiotherapy.
Topics: Adolescent; Adult; Clinical Protocols; Ear, External; Female; Humans; Keloid; Male; Postoperative Ca | 2001 |
Zimmer splintage: a simple effective treatment for keloids following ear-piercing.
Topics: Anti-Inflammatory Agents; Beauty Culture; Ear, External; Humans; Injections, Intralesional; Keloid; | 2001 |
Inflammatory-cell subpopulations in keloid scars.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Case-Control Studies; CD4-CD8 Ratio; Child; Female; Human | 2001 |
Intralesional cryosurgery using lumbar puncture and/or hypodermic needles for large, bulky, recalcitrant keloids.
Topics: Adult; Cryosurgery; Female; Humans; Keloid; Male; Middle Aged; Needles; Spinal Puncture; Treatment O | 2001 |
Treating the elusive keloid.
Topics: Combined Modality Therapy; Humans; Keloid | 2001 |
Keloids should be treated with the traditional scalpel incision followed by steroid injection.
Topics: Combined Modality Therapy; Humans; Keloid; Steroids | 2001 |
Treating keloids with carbon dioxide lasers.
Topics: Carbon Dioxide; Humans; Keloid; Laser Therapy; Recurrence | 2001 |
Energy density and numbers of treatment affect response of keloidal and hypertrophic sternotomy scars to the 585-nm flashlamp-pumped pulsed-dye laser.
Topics: Adult; Aged; Cicatrix, Hypertrophic; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Posto | 2001 |
Experience with difficult keloids.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Combined Modality Therapy; Cry | 2001 |
[Changes in TGF-beta 1 and type I, III procollagen gene expression in keloid and hypertrophic scar].
Topics: Cicatrix, Hypertrophic; Humans; Keloid; Procollagen; RNA, Messenger; Transforming Growth Factor beta | 1999 |
The role of nitric oxide in the formation of keloid and hypertrophic lesions.
Topics: Cicatrix, Hypertrophic; Collagen; Humans; Keloid; Models, Theoretical; Nitric Oxide | 2001 |
New concept of balloon-compression wear for the treatment of keloids and hypertrophic scars.
Topics: Cicatrix, Hypertrophic; Clothing; Humans; Keloid; Pressure | 2001 |
Are keloids really "gli-loids"?: High-level expression of gli-1 oncogene in keloids.
Topics: DNA; Gene Expression Regulation; Humans; Immunohistochemistry; Keloid; Oncogene Proteins; Reverse Tr | 2001 |
Clinical genetics of familial keloids.
Topics: Adolescent; Adult; Age of Onset; Black People; Child; Diseases in Twins; Female; Genes, Dominant; Hu | 2001 |
A massive plantar keloid.
Topics: Adult; Female; Foot; Foot Injuries; Humans; Keloid; Recurrence | 2001 |
Cerebriform fibrous proliferation vs. proteus syndrome.
Topics: Diagnosis, Differential; Female; Foot; Humans; Keloid; Middle Aged; Proteus Syndrome | 2001 |
[Experimental study of Bcl-2 and Fas gene expression in fibroblast of scar].
Topics: Adolescent; Adult; Apoptosis; Child; Child, Preschool; Cicatrix, Hypertrophic; fas Receptor; Female; | 2001 |
Treatment of the keloid: what is new?
Topics: Humans; Keloid | 2002 |
[Benign diseases in radiotherapy: a practice survey in Belgium. Peer review of radiotherapy in Belgium].
Topics: Belgium; Bone Diseases; Eye Diseases; Health Care Surveys; Humans; Hypothyroidism; Keloid; Practice | 2001 |
[The distrubution of cell cycle on fibrolasts derived from the pathlogical scars and analysis of Fas gene mutations in keloids using polymerse chain Reaction-based single-strand conformation polymorphism].
Topics: Adult; Cell Cycle; Cicatrix, Hypertrophic; fas Receptor; Female; Fibroblasts; Gene Deletion; Humans; | 2000 |
Bilateral congenital corneal keloids and anterior segment mesenchymal dysgenesis in a case of Rubinstein-Taybi syndrome.
Topics: Anterior Eye Segment; Corneal Diseases; Eye Abnormalities; Humans; Infant; Keloid; Keratoplasty, Pen | 2002 |
[An experimental study of antisense TGF-beta 1 inhibiting keloid fibroblast proliferation in vitro].
Topics: Antisense Elements (Genetics); Apoptosis; Cell Division; Cells, Cultured; Fibroblasts; Humans; Keloi | 2001 |
[Response of keloid fibroblasts to the effect of tumor necrosis factor-alpha(TNF-alpha)].
Topics: Collagen; Fibroblasts; Humans; Keloid; Tumor Necrosis Factor-alpha | 2001 |
A light microscopic and immunohistochemical evaluation of scars.
Topics: Actins; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cicatrix; Elastin; Female; Humans; H | 2002 |
Alterations in fibroblast alpha1beta1 integrin collagen receptor expression in keloids and hypertrophic scars.
Topics: Adult; Aged; Cells, Cultured; Child; Child, Preschool; Cicatrix, Hypertrophic; Female; Fibroblasts; | 2002 |
Blocking transforming growth factor-beta receptor signaling down-regulates transforming growth factor-beta1 autoproduction in keloid fibroblasts.
Topics: Activin Receptors, Type I; Cells, Cultured; Down-Regulation; Fibroblasts; Gene Expression; Humans; K | 2002 |
Scar modification. Techniques for revision and camouflage.
Topics: Cicatrix; Cosmetic Techniques; Decision Trees; Dermabrasion; Face; Humans; Keloid; Laser Therapy; Pl | 1998 |
Prolonged childhood Cushing's syndrome secondary to intralesional triamcinolone acetonide.
Topics: Child; Cushing Syndrome; Female; Glucocorticoids; Humans; Injections, Intralesional; Keloid; Triamci | 2002 |
Common complications of body piercing.
Topics: Adult; Cellulitis; Cosmetic Techniques; Ear, External; Female; Granuloma; Humans; Impetigo; Keloid; | 2002 |
In-situ irradiation of keloid scars with Nd:YAG laser.
Topics: Adolescent; Adult; Female; Humans; Keloid; Laser Coagulation; Male; Middle Aged; Prospective Studies | 2000 |
Case report--slowly enlarging mass of the dorsal right hand in a pregnant woman.
Topics: Adult; Diagnosis, Differential; Female; Hand; Hand Dermatoses; Humans; Keloid; Lymphatic Diseases; M | 2001 |
My husband recently had coronary bypass surgery. His heart function has improved and we're thankful, but he has a scar on his chest that's very thick and unsightly. Is there a way to treat the scar?
Topics: Bandages; Cicatrix, Hypertrophic; Coronary Artery Bypass; Humans; Keloid; Male; Silicone Gels | 2002 |
Spontaneous bleeding following steroid injection and silicone-gel sheeting in a keloid scar.
Topics: Child; Glucocorticoids; Hemorrhage; Humans; Keloid; Male; Silicone Gels; Skin Diseases; Triamcinolon | 2002 |
Differences in collagen production between normal and keloid-derived fibroblasts in serum-media co-culture with keloid-derived keratinocytes.
Topics: Cells, Cultured; Coculture Techniques; Collagen; Culture Media; Ear, External; Fibroblasts; Humans; | 2002 |
Functions of the stratum corneum in systemic sclerosis as distinct from hypertrophic scar and keloid functions.
Topics: Adult; Aged; Arm; Cicatrix, Hypertrophic; Epidermis; Female; Galvanic Skin Response; Humans; Keloid; | 2002 |
The effects of sialic acid on the gene expression of fibrillar collagens: different changes in normal and fibrotic scar derived fibroblasts.
Topics: Cells, Cultured; Cicatrix; Collagen Type I; Collagen Type III; Fibrillar Collagens; Fibroblasts; Gen | 2001 |
Keloids - the sebum hypothesis revisited.
Topics: Adolescent; Adult; Aged; Autoantigens; Child; Collagen; Female; Humans; Hypersensitivity, Delayed; K | 2002 |
Fibroblasts cocultured with keloid keratinocytes: normal fibroblasts secrete collagen in a keloidlike manner.
Topics: Adolescent; Adult; Blotting, Northern; Blotting, Western; Coculture Techniques; Collagen; Collagen T | 2002 |
Wound healing. The anatomy of healing and scarring.
Topics: Cicatrix; Humans; Keloid; Wound Healing | 2002 |
Keratinocyte-keloid interaction.
Topics: Burns; Buttocks; Cell Communication; Cell Transplantation; Cells, Cultured; Child; Extracellular Mat | 2002 |
Thrombospondin-1 may modulate keloid formation through up-regulation of the matrix-associated plasminogen/plasmin system.
Topics: Cells, Cultured; Extracellular Matrix; Fibrinolysin; Fibroblasts; Humans; Keloid; Plasminogen; Throm | 2002 |
Imiquimod: a new immune response modifier for the treatment of external genital warts and other diseases in dermatology.
Topics: Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Follow-Up Studies; Humans; Imiquim | 2002 |
[Keloid of the earlobe after ear piercing. Not only a surgical problem].
Topics: Combined Modality Therapy; Ear, External; Female; Humans; Keloid; Middle Aged; Postoperative Complic | 2002 |
Keloidal fibromas and fibrosarcomas in the dog.
Topics: Animals; Dog Diseases; Dogs; Female; Fibroma; Fibrosarcoma; Keloid; Male; Orchiectomy; Ovariectomy; | 2002 |
Pathologic scar formation. Morphologic and biochemical correlates.
Topics: Amino Acids; Chromatography; Cicatrix; Collagen; Feedback; Fibroblasts; Glycosaminoglycans; Humans; | 1977 |
Alpha globulin collagenase inhibitors in keloid and hypertrophic scar.
Topics: Alpha-Globulins; Collagen; Humans; Hypertrophy; Keloid; Microbial Collagenase; Triamcinolone | 1975 |
Elastin fibers in scar tissue.
Topics: Adolescent; Adult; Child, Preschool; Cicatrix; Elastic Tissue; Elastin; Female; Humans; Keloid; Male | 1976 |
[On the therapy of keloids and hypertrophic scars (author's trnasl)].
Topics: Adolescent; Adult; Cicatrix; Drug Evaluation; Female; Heparinoids; Humans; Hypertrophy; Keloid; Male | 1976 |
Keloid scars after burns.
Topics: Burns; Humans; Keloid | 1976 |
Tissue alpha-globulins in keloid formation.
Topics: alpha 1-Antitrypsin; Alpha-Globulins; alpha-Macroglobulins; Collagen; Humans; Keloid; Microbial Coll | 1977 |
[Scar keloids, eruptive xanthomas, mollusca contagiosa, juvenile melanoma, circumscript pretibial myxedema].
Topics: Adolescent; Adult; Aged; Female; Humans; Keloid; Melanoma; Middle Aged; Molluscum Contagiosum; Myxed | 1978 |
Closure of an abdominal hernia with a groin flap lined with a dermal graft. Case report.
Topics: Abdominal Muscles; Adult; Female; Hernia; Humans; Keloid; Pregnancy; Pregnancy Trimester, Third; Ski | 1975 |
The place of intralesional steroid therapy in dermatology.
Topics: Acne Vulgaris; Adult; Aged; Alopecia Areata; Humans; Injections, Jet; Keloid; Lupus Erythematosus, S | 1976 |
[Dermatological complications after renal transplantation (author's transl)].
Topics: Adolescent; Adult; Alopecia; Child; Dermatomycoses; Eczema; Female; Herpes Simplex; Herpes Zoster; H | 1976 |
[Excessive auricular keloid after correction of a protruding ear (author's transl)].
Topics: Adrenal Cortex Hormones; Child; Congenital Abnormalities; Ear, External; Humans; Keloid; Male; Posto | 1976 |
[Roentgen therapy of dermatoses: indications and hazards].
Topics: Acne Vulgaris; Eczema; Foot Dermatoses; Humans; Keloid; Lichen Planus; Lymphocytosis; Neoplasms, Rad | 1978 |
Radiotherapy of benign dermatoses: indications, practice, and results.
Topics: Acne Vulgaris; Bacterial Infections; Dupuytren Contracture; Eczema; Female; Hemangioma; Herpes Simpl | 1978 |
[Investigations on the ultrastructure of keloid (author's transl)].
Topics: Basement Membrane; Capillaries; Collagen; Connective Tissue; Endothelium; Fibroblasts; Glycosaminogl | 1978 |
Epibulbar tumors in childhood.
Topics: Adolescent; Amyloidosis; Carcinoma, Squamous Cell; Child; Child, Preschool; Choristoma; Conjunctiva; | 1975 |
[Knotty reticulosis with keloid formation].
Topics: Adrenocorticotropic Hormone; Glucocorticoids; Histiocytes; Humans; Keloid; Lymphatic Diseases; Lymph | 1975 |
[Dermatofibrosarcoma protuberans with 20-year duration].
Topics: Adult; Biopsy; Diagnosis, Differential; Facial Neoplasms; Female; Fibrosarcoma; Histiocytoma, Benign | 1976 |
Postoperative irradiation in the prevention of keloids.
Topics: Humans; Keloid; Time Factors; Wound Healing | 1976 |
Postoperative scars and cleavage lines.
Topics: Adult; Aged; Cicatrix; Color; Female; Head and Neck Neoplasms; Humans; Keloid; Male; Middle Aged; Ne | 1977 |
Endodontic therapy averting major surgery and avoiding keloid formation.
Topics: Abscess; Humans; Keloid; Mandibular Fractures; Root Canal Therapy; Tooth Diseases | 1978 |
The keloidal diathesis, a resistant state to malignancies?
Topics: Dinitrochlorobenzene; Disease Susceptibility; Humans; Keloid; Leukocyte Count; Skin Neoplasms; Skin | 1977 |
[Clinical picture report: "Dermatological surgery"].
Topics: Aged; Carcinoma, Basal Cell; Head and Neck Neoplasms; Humans; Keloid; Male; Middle Aged; Skin Neopla | 1977 |
Basic Operative technique.
Topics: Cicatrix; Humans; Keloid; Methods; Surgery, Plastic; Surgical Procedures, Operative; Suture Techniqu | 1977 |
Reconstruction of the microtic ear with autogenous cartilage.
Topics: Age Factors; Bacterial Infections; Cartilage; Child; Child, Preschool; Ear, External; Female; Humans | 1978 |
Long-term therapy of second and third degree burns in children using Jobst-compression suits.
Topics: Adolescent; Burns; Child; Child, Preschool; Clothing; Follow-Up Studies; Humans; Keloid; Skin Transp | 1979 |
Treatment of keloids on earlobes.
Topics: Ear Diseases; Ear, External; Humans; Injections; Keloid; Postoperative Complications; Skin Transplan | 1979 |
Correlation between X-prolyl dipeptidyl-aminopeptidase and serum amine oxidase in serum of patients with post-burn keloids.
Topics: Adolescent; Adult; Age Factors; Amine Oxidase (Copper-Containing); Amines; Burns; Child; Child, Pres | 1979 |
Audiofrequency electrotherapy in skin diseases.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatitis, Contact; Electric Stimulation Therapy; | 1977 |
Growth kinetics and collagen synthesis of normal skin, normal scar and keloid fibroblasts in vitro.
Topics: Cell Division; Cells, Cultured; Cicatrix; Collagen; Fibroblasts; Humans; Keloid; Skin | 1979 |
Immunoglobulin, complement, and histocompatibility antigen studies in keloid patients.
Topics: Adult; Complement C3; Complement C4; Female; Histocompatibility Antigens; Humans; Immunoglobulin G; | 1979 |
[Beta therapy of postburn keloid scars].
Topics: Adult; Burns; Female; Humans; Keloid; Male; Middle Aged; Radiography | 1979 |
[Lumps after ear lobe piercing].
Topics: Adolescent; Adult; Child; Ear Diseases; Ear, External; Female; Humans; Keloid | 1979 |
[Dirt-tattooing through use of sterile disposable injection needles].
Topics: Adult; Disposable Equipment; Female; Humans; Injections, Subcutaneous; Keloid; Needles; Tattooing | 1979 |
Does an immune reaction to sebum in wounds cause keloid scars? Beneficial effect of desensitisation.
Topics: BCG Vaccine; Desensitization, Immunologic; Humans; Keloid; Sebum; Skin Tests | 1979 |
Quantitative assay of types I and III collagen synthesized by keloid biopsyes and fibroblasts.
Topics: Adolescent; Adult; Biopsy; Chromatography, Agarose; Collagen; Female; Fibroblasts; Humans; Keloid; M | 1979 |
Acanthoma fissuratum. Histopathology and review of the literature.
Topics: Adolescent; Connective Tissue; Diagnosis, Differential; Ear; Granuloma; Humans; Keloid; Male; Skin D | 1979 |
[Complications in the intracutaneous BCG vaccination of young infants].
Topics: Abscess; BCG Vaccine; Child, Preschool; Humans; Infant; Infant, Newborn; Injections, Intradermal; Ke | 1979 |
Keloids: a review of current clinical evaluation and treatment.
Topics: Humans; Keloid | 1979 |
Rubinstein-Taybi syndrome and spontaneous keloids.
Topics: Abnormalities, Multiple; Adult; Female; Humans; Keloid; Rubinstein-Taybi Syndrome | 1979 |
VIII. Connective tissue diseases and aging.
Topics: Aging; Collagen Diseases; Connective Tissue Diseases; Dermatology; Humans; Keloid; Research; Researc | 1979 |
Combined modalities in the management of hypertrophic scars and keloids.
Topics: Cicatrix; Cryosurgery; Female; Humans; Hypertrophy; Keloid; Lip Diseases; Middle Aged; Triamcinolone | 1979 |
[Irradiation prophylaxis of keloids and cicatricial hypertrophies (author's transl)].
Topics: Adult; Cicatrix; Female; Humans; Hypertrophy; Keloid; Male; Postoperative Care; Radiotherapy Dosage; | 1979 |
Keloids: enigma of the plastic surgeon.
Topics: Ear, External; Facial Dermatoses; Humans; Keloid; Male; Middle Aged; Pressure; Surgery, Plastic | 1979 |
Management of children with Turner's syndrome.
Topics: Adolescent; Child; Estrogens; Female; Growth Disorders; Heart Defects, Congenital; Humans; Keloid; O | 1979 |
The effect of histamine on the growth of cultured fibroblasts isolated from normal and keloid tissue.
Topics: Cell Division; Cell Survival; Cells, Cultured; Female; Fibroblasts; Histamine; Humans; Keloid; Male | 1977 |
HLA antigens in keloids and hypertrophic scars.
Topics: Cicatrix; Histocompatibility Antigens; Humans; Hypertrophy; Keloid | 1977 |
Elevated collagen synthesis in cultured keloid fibroblasts.
Topics: Cell Division; Cicatrix; Collagen; Culture Techniques; Fibroblasts; Humans; Keloid; Skin | 1977 |
[Instralesional triamcinolone acetonide therapy of hypertrophic scars and keloids by means of pressure injectors].
Topics: Adult; Child; Cicatrix; Female; Humans; Injections, Jet; Keloid; Triamcinolone Acetonide | 1978 |
Electrosurgery by bipolar modalities.
Topics: Electrosurgery; Granuloma; Humans; Keloid; Pacemaker, Artificial; Rhinophyma; Skin Diseases; Skin Ne | 1978 |
The suppurative keloid.
Topics: Black People; Humans; Keloid; Male; Suppuration | 1978 |
Radiation therapy in the treatment of keloids.
Topics: Humans; Keloid; Postoperative Care; Preoperative Care | 1978 |
Collagen polymorphism in pathologic human scars.
Topics: Adult; Cicatrix; Collagen; Female; Fetus; Humans; Keloid; Polymorphism, Genetic; Pregnancy | 1978 |
Transurethral urethrotomy under vision.
Topics: Female; Fiber Optic Technology; Humans; Keloid; Male; Methods; Middle Aged; Postoperative Complicati | 1978 |
Auricular keloids: a simple method of management.
Topics: Ear, External; Humans; Keloid; Recurrence; Triamcinolone | 1978 |
Classification of keloids.
Topics: Age Factors; Black People; Female; Humans; Keloid; Male; Sex Factors | 1978 |
Three distinct varieties of ear lobe keloids in Egypt.
Topics: Adolescent; Adult; Child; Ear, External; Female; Humans; Keloid | 1978 |
Enormous keloid (?) on a penis.
Topics: Adult; Humans; Keloid; Male; Penile Diseases | 1978 |
Peculiarities in dermatology.
Topics: Adult; Child; Diagnosis, Differential; Female; Humans; Ichthyosis; Infant; Keloid; Leprosy; Male; Sc | 1978 |
Keloidal blastomycosis (Lobo's disease) in Panama.
Topics: Blastomycosis; Ear Diseases; Ear, External; Humans; Keloid; Male; Middle Aged; Panama | 1978 |
Miscellaneous dermatoses.
Topics: Acanthosis Nigricans; Adolescent; Athletic Injuries; Dermatomycoses; Female; Granuloma; Humans; Icht | 1978 |
New capillary collagen of cutaneous scars.
Topics: Capillaries; Cicatrix; Collagen; Humans; Keloid; Skin | 1978 |
Differential effects of hydrocortisone on both growth and collagen metabolism of human fibroblasts from normal and keloid tissue.
Topics: Cell Division; Cells, Cultured; Collagen; DNA; Fibroblasts; Humans; Hydrocortisone; Keloid | 1978 |
Surgical treatment of keloids secondary to ear piercing.
Topics: Cosmetics; Ear, External; Humans; Keloid | 1978 |
[Occlusion of the central retinal artery following injection of embolizing material (author's transl)].
Topics: Adult; Aged; Arterial Occlusive Diseases; Blindness; Carotid Arteries; Embolization, Therapeutic; Fe | 1978 |
"Pseudomelanoma" in a keloid.
Topics: Adult; Diagnosis, Differential; Female; Humans; Keloid; Melanoma; Nevus, Pigmented; Recurrence; Skin | 1978 |
The role of pressure therapy in management of earlobe keloids: preliminary report of a controlled study.
Topics: Ear, External; Humans; Keloid; Pressure; Surgery, Plastic | 1978 |
On the pathogenesis and treatment of keloid fibroma.
Topics: Adult; Female; Humans; Keloid; Male; Triamcinolone | 1978 |
The combined use of cryosurgery and intralesional injections of suspensions of fluorinated adrenocorticosteroids for reducing keloids and hypertrophic scars.
Topics: Adrenal Cortex Hormones; Cicatrix; Cryosurgery; Humans; Keloid; Triamcinolone Acetonide | 1979 |
A reappraisal of shaving and skin grafting for hypertrophic burn scars.
Topics: Adolescent; Adult; Burns; Child; Child, Preschool; Cicatrix; Female; Follow-Up Studies; Humans; Kelo | 1976 |
The diagnostic application of specific anti-procollagen sera. I. Analysis of skin biopsies.
Topics: Adolescent; Adult; Aged; Humans; Immune Sera; Keloid; Lichen Planus; Lupus Erythematosus, Discoid; L | 1976 |
The use of epidermis over a keloid as an autograft after resection of the keloid.
Topics: Humans; Keloid; Recurrence; Skin Transplantation; Transplantation, Autologous | 1976 |
[The management of occasional wounds].
Topics: Drainage; First Aid; Hemostasis; Humans; Keloid; Suture Techniques; Tetanus; Tetanus Toxoid; Wounds | 1976 |
The exzymatic determination of acidic glycosaminoglycans in scar and keloid wtih chondroitinase.
Topics: Adolescent; Adult; Child; Chondroitinases and Chondroitin Lyases; Cicatrix; Collagen; Female; Glycos | 1976 |
[Radiation therapy of keloids and hemangiomas (author's transl)].
Topics: Adrenal Cortex Hormones; Burns; DNA, Neoplasm; Hemangioma; Humans; Keloid; Radiotherapy; Skin Neopla | 1975 |
The incidence of ectopic bone formation in post-traumatic paraplegic patients of different racial groups.
Topics: Black People; Female; Humans; Keloid; Male; Ossification, Heterotopic; Paraplegia; Wounds, Stab | 1976 |
[Enzyme patterns in connective tissue proliferations (author's transl)].
Topics: Dupuytren Contracture; Fibroma; Fibrosarcoma; Glucosephosphate Dehydrogenase; Humans; Keloid; Neopla | 1977 |
The biology of keloid and hypertrophic scar and the influence of corticosteroids.
Topics: Cicatrix; Collagen; Humans; Hypertrophy; Keloid; Triamcinolone Acetonide | 1977 |
Hypertrophic scars and keloids.
Topics: Cicatrix; Humans; Hypertrophy; Keloid; Pressure; Skin Pigmentation; Triamcinolone; Wound Healing | 1977 |
Treatment of keloid.
Topics: Cortisone; Humans; Keloid; Male; Methods; Middle Aged; Neck; Triamcinolone Acetonide | 1977 |
Effect of corticosteroids on collagen synthesis.
Topics: Animals; Bone and Bones; Chick Embryo; Collagen; Humans; Keloid; Methylprednisolone; Rats; Time Fact | 1977 |
Acceptability of BCG vaccination.
Topics: BCG Vaccine; Humans; Keloid; Skin Ulcer | 1977 |
Clinical and biochemical features of normal, defective, and pathologic scars.
Topics: Cicatrix; Connective Tissue; Glycosaminoglycans; Granulation Tissue; Humans; Hypertrophy; Inflammati | 1977 |
Butterfly keloids elsewhere than presternal.
Topics: Adult; Back; Humans; Keloid; Male; Sternum; Thorax | 1977 |
The role of radiation in preventing keloids.
Topics: Humans; Keloid; Postoperative Complications | 1977 |
Complication and correction of the pierced ear.
Topics: Beauty Culture; Ear, External; Humans; Keloid; Methods; Pruritus; Punctures | 1976 |
Skin problems of blacks.
Topics: Acne Keloid; Alopecia; Black People; Female; Hair Removal; Humans; Keloid; Male; Pigmentation Disord | 1976 |
Complications associated with carotid endarterectomy.
Topics: Blood Vessels; Carotid Artery Diseases; Endarterectomy; Humans; Keloid; Postoperative Complications; | 1976 |
[Treatment of keloids and some skin diseases with topical injections of triamcinolone].
Topics: Administration, Topical; Adolescent; Adult; Child; Female; Humans; Injections; Keloid; Male; Middle | 1976 |
[The polymorphism of collagen. New viewpoints on the structure and function of connective tissue].
Topics: Age Factors; Amino Acid Sequence; Antibodies; Aorta; Cartilage; Chemical Phenomena; Chemistry; Colla | 1976 |
[Problems of incidents in BCG vaccination].
Topics: Abscess; Austria; BCG Vaccine; Child, Preschool; Humans; Infant; Infant, Newborn; Keloid; Lymphadeni | 1976 |
Vaccination caveat. The off-the-shoulder look.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Cicatrix; Female; Humans; Infant; Keloid; Shoulder | 1976 |
A case of large keloid of the neck in an African patient.
Topics: Black People; Humans; Keloid; Male; Neck; Zimbabwe | 1976 |
Effect of a concurrent immune response on the collagen synthesis around implanted Ivalon sponges in rats.
Topics: Animals; Antibodies; Collagen; Dinitrochlorobenzene; Freund's Adjuvant; Granulation Tissue; Immunity | 1976 |
[Gonadal load in radiotherapy of benign diseases. II. Infectious diseases and keloids].
Topics: Female; Gonads; Humans; Keloid; Mastitis; Parotitis; Pregnancy; Radiation Protection; Radiotherapy D | 1976 |
Scanning electron microscopy of normal human scar tissue and keloids.
Topics: Adult; Cicatrix; Collagen; Connective Tissue; Connective Tissue Cells; Fibroblasts; Humans; Keloid; | 1976 |
Unusual complications of triamcinolone injected keloids: tissue necrosis and systemic corticosteroid effects.
Topics: Adolescent; Adult; Cushing Syndrome; Female; Humans; Keloid; Necrosis; Triamcinolone Acetonide | 1976 |
Lobomycosis. Report of the eighth Colombian case and review of the literature.
Topics: Adult; Blastomycosis; Chronic Disease; Female; Humans; Keloid | 1976 |
[Treatment of old keloids].
Topics: Humans; Keloid; Methods | 1976 |
Cosmetic aspects of cryosurgery.
Topics: Adenoma; Cryosurgery; Fibroma; Humans; Keloid; Keratosis; Nevus, Pigmented; Sebaceous Gland Neoplasm | 1976 |
[Mediastinoscopy and scar-keloid's in boeck's sarcoid (author's transl)].
Topics: Adult; Female; Humans; Keloid; Male; Mediastinal Neoplasms; Mediastinoscopy; Middle Aged; Sarcoidosi | 1976 |
[The clip: treatment of keloids of the ear lobe by sustained, prolonged compression].
Topics: Dermatology; Ear Diseases; Ear, External; Keloid | 1976 |
On the [4-14C]progesterone metabolism of keloid and hypertrophic scar. A preliminary report.
Topics: Adolescent; Adult; Cicatrix; Female; Humans; Hypertrophy; Keloid; Male; Middle Aged; Progesterone; S | 1976 |
Cushing's syndrome associated with the intradermal injection of triamcinolone diacetate.
Topics: Adolescent; Cushing Syndrome; Humans; Injections, Intradermal; Keloid; Male; Triamcinolone | 1976 |
Facial scars resulting from vehicular accidents.
Topics: Accidents, Traffic; Automobile Driving; Burns; Cicatrix; Dermabrasion; Facial Injuries; Hair; Humans | 1975 |
Keloid management and its present status.
Topics: Age Factors; Foreign-Body Reaction; Humans; Infections; Keloid; Sex Factors; Steroids, Fluorinated; | 1975 |
A 10-year experience with subcutaneous mastectomy.
Topics: Adult; Breast Neoplasms; Cicatrix; Dissection; Female; Follow-Up Studies; Hemostasis; History, 20th | 1975 |
Presumptive evidence of the effect of pregnancy estrogens on keloid growth. Case report.
Topics: Adult; Ear Deformities, Acquired; Ear, External; Estrogens; Female; Humans; Keloid; Pregnancy; Pregn | 1975 |
Defined immunofluorescence studies of anticollagen sera.
Topics: Collagen; Epidermolysis Bullosa; Fluorescent Antibody Technique; Glucocorticoids; Immune Sera; Keloi | 1975 |
[Surgical treatment of elephantiasis of the upper extremities].
Topics: Adolescent; Adult; Arm; Child; Child, Preschool; Chronic Disease; Elephantiasis; Female; Humans; Kel | 1975 |
Lobomycosis as a disease of the Atlantic bottle-nosed dolphin (Tursiops truncatus Montagu, 1821).
Topics: Animals; Blastomycosis; Dolphins; Female; Florida; Keloid; Macaca; Macrophages; Mice; Skin | 1975 |
[Characteristics of the diagnosis and treatment of scabies in burned patients].
Topics: Burns; Humans; Keloid; Scabies | 1975 |
Cryosurgery in dermatologic office practice: special reference to dermatofibroma and mucous cyst of the lip.
Topics: Cryosurgery; Cysts; Dermatology; Fibroma; Humans; Keloid; Keratosis; Lip Diseases; Minor Surgical Pr | 1975 |
Osteopoikilosis: possible association with dystocia and keloid.
Topics: Adult; Dystocia; Female; Humans; Keloid; Middle Aged; Osteopoikilosis; Osteosclerosis; Pelvis; Pregn | 1975 |
Collagen biosynthesis in normal human skin, normal and hypertrophic scar and keloid.
Topics: Carbon Radioisotopes; Cicatrix; Collagen; Humans; Hydroxyproline; Hypertrophy; In Vitro Techniques; | 1975 |
[Tissue reactivity and its relation to cancers of the skin].
Topics: Cicatrix; Humans; Keloid; Postoperative Complications; Precancerous Conditions; Radiation Injuries; | 1975 |
[Treatment of auricular keloids].
Topics: Adolescent; Adult; Child; Ear, External; Female; Humans; Hydrocortisone; Keloid | 1975 |
Tissue reaction and its relation to skin cancer.
Topics: Burns; Cicatrix; Humans; Keloid; Precancerous Conditions; Skin Neoplasms; Skin Pigmentation; Wound H | 1975 |
A technique for excising earlobe keloids.
Topics: Ear, External; Humans; Keloid; Methods | 1975 |
A focus on the occupational health needs of the non-white worker.
Topics: Anemia, Sickle Cell; Culture; Economics; Ethnicity; Female; Health Education; Humans; Keloid; Male; | 1975 |
Collagen biosynthesis in normal and hypertrophic scars and keloid as a function of the duration of the scar.
Topics: Cicatrix; Collagen; Humans; Hydroxyproline; Hypertrophy; In Vitro Techniques; Keloid; Kinetics; Prol | 1975 |
[Multiple keloids developing in an elderly patient with pruritus].
Topics: Anabolic Agents; Female; Humans; Keloid; Middle Aged; Paranoid Disorders; Prednisolone; Pruritus; Vi | 1975 |
[Clinical evaluation of x-ray therapy in the treatment of keloid as compared with other therapeutic methods].
Topics: Female; Humans; Keloid; Male; Radiotherapy Dosage; X-Ray Therapy | 1975 |
Genetic studies on keloid.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Fema | 1975 |
Effects of intralesional injection of triamcinolone on glucose-6-phosphate dehydrogenase and alanine aminotransferase activity in keloids.
Topics: Alanine Transaminase; Collagen; DNA, Neoplasm; Ear Neoplasms; Glucosephosphate Dehydrogenase; Inject | 1975 |
Ultrastructure of keloid: an unusual incident involving lepromatous leprosy.
Topics: Adult; Blood Vessels; Cicatrix; Collagen; Connective Tissue; Connective Tissue Cells; Cytoplasm; End | 1975 |
[Cicatrization and esthetics].
Topics: Esthetics; Humans; Keloid; Wound Healing | 1975 |
Radiation therapy of keloids.
Topics: Humans; Keloid; Radiotherapy | 1975 |
Cryosurgery of skin cancer--in proper perspective.
Topics: Carcinoma, Basal Cell; Cryosurgery; Ear Neoplasms; Eyelid Neoplasms; Facial Neoplasms; Follow-Up Stu | 1975 |
[The keloid. Thoughts on therapy].
Topics: Humans; Keloid; Methods | 1975 |
[Treatment of hypertrophic and keloid cicatrices with thiomucase].
Topics: Burns; Chondroitinases and Chondroitin Lyases; Chondroitinsulfatases; Cicatrix; Dexamethasone; Drug | 1975 |
[Treatment with hyaluronidase in dermatology].
Topics: Humans; Hyaluronoglucosaminidase; Keloid; Male; Penile Induration; Scleroderma, Localized; Scleroder | 1975 |
[Changes in capillary circulation and lymphatic resorption in keloid scars following burns].
Topics: Adolescent; Adult; Aged; Burns; Female; Humans; Keloid; Lymphatic System; Male; Microcirculation; Mi | 1975 |
Corneal keloid.
Topics: Child; Corneal Diseases; Humans; Keloid; Male; Smallpox | 1975 |
Cell size and growth characteristics of cultured fibroblasts isolated from normal and keloid tissue.
Topics: Cells, Cultured; Cicatrix; Fibroblasts; Growth; Humans; Karyotyping; Keloid; Skin | 1976 |
Enzyme activity in human scars, hypertrophic scars and keloids.
Topics: Acid Phosphatase; Alkaline Phosphatase; Cicatrix; Glucuronidase; Humans; Hypertrophy; Keloid; L-Lact | 1976 |
Symposium: the supra-tip in rhinoplasty: a dilemma. II. Influence of surrounding structure and prevention.
Topics: Humans; Keloid; Nasal Septum; Nose Deformities, Acquired | 1976 |
The evolution of pre-sternal keloids.
Topics: Adult; Female; Humans; Keloid; Male; Sternum; Triamcinolone Acetonide | 1976 |
Keloids of the ear lobes in Egypt: their rarity in childhood and their treatment.
Topics: Adolescent; Adult; Age Factors; Child; Ear Diseases; Ear, External; Egypt; Female; Humans; Keloid; S | 1976 |
Scanning electronmicroscopy of hypertrophic and keloid scar.
Topics: Cicatrix; Humans; Hypertrophy; Keloid | 1976 |
Keloid scars: a new method of treatment combining surgery with interstitial radiotherapy.
Topics: Follow-Up Studies; Humans; Iridium; Keloid; Polyethylenes; Postoperative Care; Postoperative Complic | 1976 |
Keloid formation in a simple syndactyly release: a case report.
Topics: Fingers; Hand Dermatoses; Humans; Infant; Keloid; Postoperative Complications; Syndactyly | 1992 |
[Keloid paracoccidioidomycosis assessed with gallium].
Topics: Citrates; Citric Acid; Gallium; Humans; Keloid; Male; Middle Aged; Paracoccidioidomycosis; Radionucl | 1992 |
Growth factors and racial differences in severity of hypertension and renal diseases.
Topics: Black People; Female; Fibroblasts; Growth Substances; Humans; Hypertension; Hypertrophy; Keloid; Mus | 1992 |
[Effect of tranilast, an anti-allergic drug, on the human keloid tissues].
Topics: Animals; Cell Division; Cells, Cultured; Collagen; Disease Models, Animal; Extracellular Matrix; Fib | 1992 |
[Effect of tranilast, an anti-allergic drug, on carrageenin-induced granulation and capillary permeability in rats].
Topics: Adult; Animals; Capillary Permeability; Carrageenan; Cicatrix; Disease Models, Animal; Dose-Response | 1992 |
Keloids of the external ear.
Topics: Adult; Child; Ear Deformities, Acquired; Ear Diseases; Ear, External; Esthetics; Female; Follow-Up S | 1992 |
Acne keloidalis aggravated by football helmets.
Topics: Acne Vulgaris; Adult; Football; Head Protective Devices; Humans; Keloid; Male; Scalp Dermatoses | 1992 |
Lip stent for positive pressure in keloid treatment.
Topics: Acrylic Resins; Adult; Equipment Design; Female; Humans; Keloid; Lip Diseases; Pressure; Stents | 1992 |
Neck resurfacing with free tram flap.
Topics: Adult; Burns; Contracture; Female; Humans; Keloid; Male; Neck; Neck Injuries; Surgical Flaps | 1992 |
Fibronectin gene transcription is enhanced in abnormal wound healing.
Topics: Adult; Female; Fibroblasts; Fibronectins; Gene Expression; Humans; Karyotyping; Keloid; Middle Aged; | 1992 |
Keloid fibroblasts exhibit an altered response to TGF-beta.
Topics: Adolescent; Adult; Cell Line, Transformed; Female; Fibroblasts; Gene Expression Regulation; Humans; | 1992 |
[Keloid cicatrix of the face and neck. Apropos of 81 cases treated in Dakar].
Topics: Adolescent; Adult; Child; Facial Dermatoses; Female; Humans; Keloid; Male; Neck; Senegal; Triamcinol | 1992 |
Failed tracheotomy decannulation in children.
Topics: Arytenoid Cartilage; Child; Cricoid Cartilage; Humans; Infant; Intubation, Intratracheal; Joint Disl | 1992 |
Keloids: a study of the immune reaction to sebum.
Topics: Adolescent; Adult; Female; Hospitals, University; Humans; Hypersensitivity, Delayed; Keloid; Male; M | 1992 |
Nodular variety of keloid simulating neoplasia.
Topics: Diagnosis, Differential; Foot Diseases; Humans; Keloid; Neoplasms | 1992 |
Nodular (keloidal) scleroderma.
Topics: Adult; Female; Humans; Keloid; Scleroderma, Systemic; Skin | 1992 |
Altered cytokine production in black patients with keloids.
Topics: Black People; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-alpha; Interferon-gam | 1992 |
Surgical considerations in tracheal stenosis.
Topics: Adolescent; Adult; Aged; Female; Follow-Up Studies; Granulation Tissue; Humans; Keloid; Laryngosteno | 1992 |
Hypertrophic scars and keloids.
Topics: Cicatrix; Humans; Hypertrophy; Keloid; Sebaceous Glands | 1992 |
Versatile use of skin expanders in facial plastic surgery.
Topics: Adolescent; Adult; Cleft Lip; Face; Female; Humans; Keloid; Male; Nasal Mucosa; Nevus; Scalp; Sebace | 1992 |
Binding and internalization of hyaluronate by human cutaneous fibroblasts.
Topics: Cells, Cultured; Cicatrix; Contact Inhibition; Endocytosis; Fibroblasts; Glycosaminoglycans; Humans; | 1992 |
Epidermal nevus: surgical treatment by partial-thickness skin excision.
Topics: Child; Electrocoagulation; Humans; Keloid; Male; Neoplasms, Multiple Primary; Nevus, Pigmented; Post | 1992 |
Keloid fibroblasts are refractory to inhibition of DNA synthesis by phorbol esters. Altered response is accompanied by reduced sensitivity to prostaglandin E2 and altered down-regulation of phorbol ester binding sites.
Topics: Binding Sites; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Dinoprostone; DNA | 1992 |
[Cortisone jet injection as therapy of hypertrophic scars and keloids].
Topics: Adolescent; Adult; Cicatrix; Female; Follow-Up Studies; Humans; Hypertrophy; Injections, Intralesion | 1992 |
Keloid.
Topics: Humans; Keloid; Male; Middle Aged | 1992 |
Posterior auricular keloids as a complication of conchal cartilage grafts in blacks.
Topics: Adult; Black People; Ear Cartilage; Ear Diseases; Humans; Keloid; Male; Rhinoplasty; Transplantation | 1992 |
Intra- and postoperative steroid injections for keloids and hypertrophic scars.
Topics: Adult; Cicatrix; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypertrophy; Injectio | 1992 |
Evaluation of various methods of treating keloids and hypertrophic scars: a 10-year follow-up study.
Topics: Adolescent; Cicatrix; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypertrophy; Kel | 1992 |
Combined surgery and irradiation for treatment of hypertrophic scars and keloids.
Topics: Adolescent; Adult; Child; Cicatrix; Combined Modality Therapy; Female; Humans; Keloid; Male | 1991 |
[Angioarchitecture of keloids. A scanning electron microscopy study of a corrosion specimen].
Topics: Adult; Capillaries; Humans; Keloid; Male; Microscopy, Electron, Scanning; Muscle, Smooth, Vascular; | 1990 |
Combined use of in situ hybridization and unlabeled antibody peroxidase anti-peroxidase methods: simultaneous detection of type I procollagen mRNAs and factor VIII-related antigen epitopes in keloid tissue.
Topics: DNA; Epitopes; Factor VIII; Fibrosis; Gene Expression; Humans; Immunoenzyme Techniques; Keloid; Nucl | 1991 |
An approach to management of keloids.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hyaluronoglucosaminidase; Injections; Keloid; Lase | 1992 |
Differential oxygen sensitivities in G6PDH activities of cultured keloid and normal skin dermis single cells.
Topics: Adolescent; Adult; Cells, Cultured; Female; Glucosephosphate Dehydrogenase; Humans; Keloid; Male; Mi | 1991 |
Contact allergy to palmitoyl collagenic acid in an anti-keloid cream.
Topics: Adult; Amino Acids; Dermatitis, Contact; Drug Eruptions; Female; Humans; Keloid; Palmitates | 1991 |
Hypertrophic scar and keloid.
Topics: Cicatrix; Diagnosis, Differential; Humans; Hypertrophy; Keloid | 1991 |
Keloid formation on palmar surface of hand.
Topics: Adult; Female; Hand; Hand Dermatoses; Humans; Keloid; Postoperative Complications | 1991 |
Endothelial cell growth factor and heparin regulate collagen gene expression in keloid fibroblasts.
Topics: Adult; Blotting, Northern; Cells, Cultured; Collagen; DNA Probes; Endothelial Growth Factors; Fibrob | 1991 |
The effect of carbon dioxide laser surgery on the recurrence of keloids.
Topics: Adolescent; Adult; Aged; Carbon Dioxide; Child; Child, Preschool; Female; Humans; Keloid; Laser Ther | 1991 |
Abnormalities of the breast caused by biopsy: spectrum of mammographic findings.
Topics: Biopsy, Needle; Breast; Breast Diseases; Calcinosis; Cicatrix; Fat Necrosis; Female; Hematoma; Human | 1991 |
Implants of keloid and hypertrophic scars into the athymic nude mouse: changes in the glycosaminoglycans of the implants.
Topics: Adolescent; Adult; Animals; Chondroitin Lyases; Chondroitin Sulfates; Cicatrix; Female; Glycosaminog | 1991 |
Effects of pharmacologic agents on human keloids implanted in athymic mice. A pilot study.
Topics: Acetylcysteine; Adolescent; Adult; Animals; Colchicine; Female; Humans; Keloid; Male; Mice; Mice, Nu | 1991 |
Collagen mRNA expression detected by in situ hybridization in keloid tissue.
Topics: Adult; Cells, Cultured; Collagen; Female; Fibroblasts; Gene Expression; Humans; Keloid; Male; Nuclei | 1991 |
Dose estimation in postoperative keloid irradiation with special consideration of ovarian dose.
Topics: Brachytherapy; Female; Humans; Iodine Radioisotopes; Iridium Radioisotopes; Keloid; Ovary; Postopera | 1991 |
[Heat therapy in the comprehensive treatment of keloid scars with laser].
Topics: Adolescent; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Hyperthermia, Induce | 1991 |
Carbon dioxide laser for keloids.
Topics: Adolescent; Adult; Carbon Dioxide; Child; Humans; Keloid; Laser Therapy; Recurrence | 1991 |
Silicone gel in the treatment of keloids.
Topics: Administration, Topical; Adult; Female; Gels; Humans; Keloid; Silicones | 1990 |
Why more keloids on back than on front of earlobe.
Topics: Ear Diseases; Ear, External; Humans; Keloid; Punctures | 1990 |
[Unusual migration of the testis].
Topics: Child; Cryptorchidism; Humans; Inguinal Canal; Keloid; Male; Suture Techniques; Testis | 1990 |
Transtracheal delivery of oxygen: efficacy and safety for long-term continuous therapy.
Topics: Adult; Aged; Cellulitis; Dermatitis, Contact; Equipment Design; Female; Follow-Up Studies; Hemoptysi | 1991 |
Topical cyclosporin and T lymphocytes in keloid scars.
Topics: Administration, Topical; Adult; Cyclosporins; Humans; Keloid; Male; T-Lymphocytes | 1991 |
Sclerokeratoplasty in a case of corneal keloid.
Topics: Child; Cicatrix; Corneal Diseases; Corneal Transplantation; Eye Injuries, Penetrating; Humans; Keloi | 1991 |
The prevention and management of postdermabrasion complications.
Topics: Dermabrasion; Female; Humans; Keloid; Pigmentation Disorders; Skin Diseases | 1991 |
[The radiotherapy of vaginal keloids by an intracavity high-dose-rate (HDR) afterloading procedure].
Topics: Adult; Brachytherapy; Female; Humans; Keloid; Postoperative Complications; Radiotherapy Dosage; Vagi | 1991 |
Activation of collagen gene expression in keloids: co-localization of type I and VI collagen and transforming growth factor-beta 1 mRNA.
Topics: Adolescent; Adult; Collagen; Gene Expression Regulation; Humans; Immunoenzyme Techniques; Keloid; Nu | 1991 |
Purification and characterization of iduronic acid-rich and glucuronic acid-rich proteoglycans implicated in human post-burn keloid scar.
Topics: Amino Acid Sequence; Amino Acids; Biopolymers; Burns; Disaccharides; Electrophoresis, Cellulose Acet | 1990 |
[Cryosurgical treatment of hypertrophic scars and keloids].
Topics: Adolescent; Adult; Child; Cicatrix; Cryosurgery; Female; Humans; Hypertrophy; Keloid; Male; Middle A | 1990 |
The role of kilovoltage irradiation in the treatment of keloids.
Topics: Adolescent; Adult; Child; Combined Modality Therapy; Female; Humans; Keloid; Male; Middle Aged; Radi | 1990 |
Intralesional interferon gamma treatment for keloids and hypertrophic scars.
Topics: Adult; Cicatrix; Female; Humans; Hypertrophy; Injections, Intralesional; Interferon-gamma; Keloid; M | 1990 |
Single-dose electron beam irradiation in treatment and prevention of keloids and hypertrophic scars.
Topics: Adult; Cicatrix; Female; Humans; Keloid; Male; Postoperative Care; Radiotherapy Dosage; Radiotherapy | 1990 |
[A case with reconstruction of the floor of the oral cavity and mandibular region with the D-P flap after resection of giant keloid and radiation scar of the mandibular].
Topics: Adult; Bone Transplantation; Female; Humans; Keloid; Mandible; Mouth Floor; Radiation Injuries; Surg | 1990 |
Pentoxifylline inhibits the proliferation of human fibroblasts derived from keloid, scleroderma and morphoea skin and their production of collagen, glycosaminoglycans and fibronectin.
Topics: Cell Division; Collagen; Depression, Chemical; Fibroblasts; Fibronectins; Glycosaminoglycans; Humans | 1990 |
[The provision of radiation safety for patients during the x-ray therapy of keloid scars].
Topics: Humans; Keloid; Radiation Protection; Radiotherapy Dosage; Safety; Time Factors | 1990 |
[Effect of minoxidil on DNA synthesis in cultured fibroblasts from healthy skin or keloids].
Topics: Cell Division; DNA; Dose-Response Relationship, Drug; Fibroblasts; Humans; Keloid; Minoxidil | 1990 |
Alteration of collagen composition and cross-linking in keloid tissues.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Collagen; Cyanogen Bromide; Humans; Keloid; Middl | 1990 |
Tissue expansion for the treatment of keloids.
Topics: Follow-Up Studies; Humans; Intraoperative Care; Keloid; Postoperative Complications; Preoperative Ca | 1990 |
Keloids and hypertrophic scars.
Topics: Cicatrix; Humans; Hypertrophy; Keloid | 1990 |
Tumefactive amyloidosis: a plantar pedal presentation.
Topics: Adult; Amyloid; Amyloidosis; Foot Diseases; Humans; Keloid; Male; Orthotic Devices; Recurrence | 1990 |
Early experience with reconstructive surgery at Mpilo Central Hospital, Zimbabwe.
Topics: Adolescent; Adult; Burns; Child; Contracture; Female; Humans; Keloid; Male; Middle Aged; Pressure Ul | 1990 |
Bilateral keloid-like myofibroblastic proliferations of the cornea in children.
Topics: Child, Preschool; Collagen; Corneal Diseases; Corneal Stroma; Fibroblasts; Humans; Infant; Keloid; K | 1990 |
Umbilical keloid: an early start.
Topics: Age Factors; Humans; Infant; Keloid; Recurrence; Surgery, Plastic; Umbilicus | 1990 |
Keloids and diabetes in a family.
Topics: Administration, Cutaneous; Diabetes Mellitus, Type 1; Humans; Insulin; Keloid; Male; Middle Aged; Pe | 1990 |
Umbilical stump keloid.
Topics: Cicatrix; Humans; Hypertrophy; Infant; Keloid; Male; Umbilicus | 1990 |
The role of lymphocytes in wound healing.
Topics: Cicatrix; Female; Humans; Hypertrophy; Keloid; Leukocyte Count; Lymphocytes; Macrophages; Receptors, | 1990 |
[Changes in the structure of postburn keloid scars before and after cryotherapy].
Topics: Amino Acids; Biopsy; Burns; Collagen; Cryosurgery; Histocytochemistry; Humans; Keloid; Microscopy, E | 1990 |
On the nature of keloid and hypertrophic scars.
Topics: Adolescent; Adult; Black People; Child; Child, Preschool; Cicatrix; Female; Humans; Hypertrophy; Kel | 1990 |
Inhibition of human fibroblast growth in vitro by a snake oil.
Topics: Animals; Cell Count; Cells, Cultured; Fibroblasts; Humans; Keloid; Mitosis; Oils; Olive Oil; Plant O | 1990 |
[Postoperative prevention of hypertrophic scars and keloids using radiotherapy].
Topics: Adolescent; Adult; Aged; Child; Cicatrix; Combined Modality Therapy; Female; Humans; Keloid; Male; M | 1990 |
Extensive keloids following hair transplantation.
Topics: Alopecia; Hair; Humans; Keloid; Male; Middle Aged; Postoperative Complications; Scalp | 1990 |
Effect of dextran sulfate on the growth of cultured fibroblasts derived from normal human skin and keloid lesions.
Topics: Adolescent; Adult; Cell Division; Cells, Cultured; Dextran Sulfate; Dextrans; Dose-Response Relation | 1987 |
["Spontaneous" keloid: what's new since 1816?].
Topics: History, 19th Century; Keloid | 1987 |
Glucocorticoid receptors in cultured human skin fibroblasts: evidence for down-regulation of receptor by glucocorticoid hormone.
Topics: Cells, Cultured; Dexamethasone; Diabetes Mellitus; Fibroblasts; Humans; In Vitro Techniques; Keloid; | 1987 |
Auriculoplasty for keloid scars.
Topics: Adolescent; Adult; Ear, External; Evaluation Studies as Topic; Female; Humans; Keloid; Male; Middle | 1989 |
[Concentrations of tranilast in keloid tissues].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Keloid; Male; Middle Aged; ortho-A | 1989 |
Cutaneous laser surgery.
Topics: Facial Neoplasms; Humans; Keloid; Laser Therapy; Nose Neoplasms; Skin Neoplasms; Surgery, Plastic; T | 1989 |
Failure of carbon dioxide laser excision of keloids.
Topics: Adult; Aged; Carbon Dioxide; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged; Recurrence; T | 1989 |
Fibronectin is overproduced by keloid fibroblasts during abnormal wound healing.
Topics: Adult; Cells, Cultured; Female; Fibroblasts; Fibronectins; Humans; Keloid; Male; Receptors, Fibronec | 1989 |
Short-term keloid treatment in vivo with human interferon alfa-2b results in a selective and persistent normalization of keloidal fibroblast collagen, glycosaminoglycan, and collagenase production in vitro.
Topics: Cell Division; Cells, Cultured; Collagen; Fibroblasts; Fibronectins; Glycosaminoglycans; Humans; Int | 1989 |
Congenital corneal keloid.
Topics: Corneal Opacity; Corneal Stroma; Corneal Transplantation; Epithelium; Female; Humans; Infant; Keloid | 1989 |
Treatment of keloid scars.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Child; Child, Preschool; Cicatrix; Combined Modali | 1985 |
Keloids and neoplasms in the Rubinstein-Taybi syndrome.
Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Female; Humans; Infant; Infant, | 1989 |
Treatment of keloids with surgical excision and postoperative X-ray radiation.
Topics: Adult; Attitude to Health; Combined Modality Therapy; Evaluation Studies as Topic; Female; Follow-Up | 1989 |
A keloidal scar of the floor of the mouth and its associations. Case report.
Topics: Adult; Cicatrix; Female; Humans; Keloid; Mouth Diseases; Mouth Floor | 1989 |
Functions of polymorphonuclear leukocytes and individuality of Jorge Lobo's disease: absence of the specific leukocyte digestive defect against Paracoccidioides brasiliensis.
Topics: Antibodies, Fungal; Blastomycosis; Humans; Keloid; Male; Neutrophils; Paracoccidioides; Paracoccidio | 1989 |
Increased fibronectin production by cell lines from hypertrophic scar and keloid.
Topics: Cell Line; Cicatrix; Enzyme-Linked Immunosorbent Assay; Epidermal Cells; Epidermis; Fibroblasts; Fib | 1989 |
HMB-45 recognizes stimulated melanocytes.
Topics: Antibodies, Monoclonal; Antigens; Binding Sites, Antibody; Cicatrix; Cytoplasm; Ecchymosis; Fibroma; | 1989 |
Implants of hypertrophic scars and keloids into the nude (athymic) mouse: viability and morphology.
Topics: Animals; Cicatrix; Graft Survival; Granulation Tissue; Hypertrophy; Keloid; Mice; Mice, Nude; Microc | 1989 |
Radiation therapy following keloidectomy: a 20-year experience.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Combined Modality Therapy; Female; Follow-Up Studi | 1989 |
[Scars. The normal scar and serious and mild anomalous scars].
Topics: Cicatrix; Humans; Keloid; Skin Physiological Phenomena; Wound Healing | 1989 |
[Results of scar keloid prevention using contact irradiation with strontium 90].
Topics: Adult; Brachytherapy; Cicatrix; Female; Humans; Keloid; Male; Strontium Radioisotopes | 1989 |
Differential glucocorticoid regulation of collagen mRNAs in human dermal fibroblasts. Keloid-derived and fetal fibroblasts are refractory to down-regulation.
Topics: Adult; Blotting, Northern; Cell Line; Cells, Cultured; Cicatrix; Collagen; DNA Probes; Fetus; Fibrob | 1989 |
The intraligamental dental syringe facilitates steroid injection into hypertrophic scars and keloids.
Topics: Cicatrix; Humans; Injections, Subcutaneous; Keloid; Steroids; Syringes | 1989 |
Keloid fibroblasts in culture: abnormal growth behaviour and altered response to the epidermal growth factor.
Topics: Adult; Cell Division; Cells, Cultured; Epidermal Growth Factor; Fibroblasts; Humans; Keloid; Skin; T | 1989 |
Use of nude (athymic) mice for the study of hypertrophic scars and keloids: vascular continuity between mouse and implants.
Topics: Anastomosis, Surgical; Animals; Cicatrix; Dermatologic Surgical Procedures; Disease Models, Animal; | 1989 |
Plasma fibronectin deficiency in eight members of one family.
Topics: Adolescent; Adult; Aged; Child, Preschool; Female; Fibronectins; Genetic Carrier Screening; Humans; | 1986 |
[Treatment methods of keloid and hypertrophic scar formation].
Topics: Child; Cicatrix; Humans; Hypertrophy; Keloid; Male; Middle Aged | 1989 |
Silicone gel in the treatment of keloid scars.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Gels; Humans; Keloid; Male; Silicones; Skin; Ski | 1989 |
[Dermabrasion--indications, technic, possibilities, complications].
Topics: Acne Vulgaris; Dermabrasion; Female; Humans; Keloid; Male; Rhinophyma; Tattooing | 1985 |
Laser surgery for children.
Topics: Acne Vulgaris; Child; Cicatrix; Hemangioma; Humans; Keloid; Laser Therapy; Pigmentation Disorders; S | 1987 |
Delayed wound healing and keloid formation following argon laser treatment or dermabrasion during isotretinoin treatment.
Topics: Acne Vulgaris; Adult; Aged; Dermabrasion; Female; Humans; Isomerism; Isotretinoin; Keloid; Laser The | 1988 |
Experience with the Nd:YAG laser in the treatment of keloid scars.
Topics: Acne Vulgaris; Adolescent; Child; Cicatrix; Humans; Keloid; Laser Therapy; Male; Skin; Wound Healing | 1988 |
Modulation of procollagen gene expression by retinoids. Inhibition of collagen production by retinoic acid accompanied by reduced type I procollagen messenger ribonucleic acid levels in human skin fibroblast cultures.
Topics: Cells, Cultured; Collagen; Endopeptidases; Fibroblasts; Gene Expression Regulation; Humans; Keloid; | 1985 |
Atypical keloids after dermabrasion of patients taking isotretinoin.
Topics: Acne Vulgaris; Adult; Dermabrasion; Female; Humans; Isotretinoin; Keloid; Male; Microbial Collagenas | 1986 |
[Skin expansion in the restorative surgery of burns].
Topics: Adolescent; Adult; Burns; Child; Child, Preschool; Cicatrix; Female; Humans; Keloid; Male; Methods; | 1988 |
[Effect of cryogenic action on the proteinase activity in patients with keloid and hypertrophic scars].
Topics: Adolescent; Adult; Child; Child, Preschool; Chronic Disease; Cicatrix; Cryosurgery; Endopeptidases; | 1988 |
Myofibroblasts in head and neck surgery. An experimental and clinical study.
Topics: Animals; Cicatrix; Fibroblasts; Head; Humans; Hypertrophy; Immunoenzyme Techniques; Keloid; Microsco | 1988 |
Clinical use of a tissue expander--enhanced transposition flap for face and neck reconstruction.
Topics: Adult; Burns, Electric; Face; Female; Humans; Keloid; Male; Methods; Neck; Neck Injuries; Prostheses | 1988 |
Disturbances of wound healing.
Topics: Cicatrix; Drug-Related Side Effects and Adverse Reactions; Emergencies; Epithelium; Humans; Ischemia | 1988 |
Lasers in private dermatologic practice.
Topics: Argon; Carbon Dioxide; Hematoma; Herpes Simplex; Humans; Keloid; Laser Therapy; Lasers; Lymphadeniti | 1986 |
Systemic response to intralesional steroid therapy.
Topics: Adult; Benzyl Alcohols; Benzyl Compounds; Humans; Keloid; Male; Triamcinolone Acetonide | 1988 |
Possible use of the Radovan tissue expander in hair replacement surgery.
Topics: Adult; Hair; Humans; Keloid; Male; Polyethylene Terephthalates; Prostheses and Implants; Scalp; Surg | 1985 |
Keloid formation after cleft lip repair.
Topics: Cleft Lip; Female; Humans; Infant; Keloid; Reoperation; Surgery, Plastic | 1988 |
Role of ionizing irradiation for 393 keloids.
Topics: Combined Modality Therapy; Esthetics; Female; Humans; Keloid | 1988 |
Retinoic acid in the treatment of keloids.
Topics: Administration, Topical; Drug Administration Schedule; Female; Humans; Keloid; Male; Tretinoin | 1988 |
[The rotation forearm flap].
Topics: Dupuytren Contracture; Hand; Humans; Keloid; Surgical Flaps | 1988 |
Ultrastructural characteristics of keloid fibroblasts.
Topics: Adult; Endoplasmic Reticulum; Female; Fibroblasts; Golgi Apparatus; Humans; Keloid; Male; Middle Age | 1988 |
[Keloidal blastomycosis (Lobo's disease)].
Topics: Adolescent; Biopsy; Blastomycosis; Combined Modality Therapy; Diagnosis, Differential; Humans; Keloi | 1988 |
[The development of keloid scars in a female vitiligo patient].
Topics: Adult; Female; Humans; Keloid; Skin; Vitiligo | 1988 |
[Use of a helium-neon laser in the ambulatory treatment of hypertrophic skin cicatrices and slowly granulating wounds].
Topics: Adolescent; Adult; Aged; Ambulatory Care; Child; Cicatrix; Granulation Tissue; Helium; Humans; Hyper | 1988 |
Effectiveness of silastic sheet coverage in the treatment of scar keloid (hypertrophic scar)
Topics: Acne Keloid; Adolescent; Burns; Child; Cicatrix; Evaluation Studies as Topic; Female; Humans; Hypert | 1988 |
Treatment of keloids by single intraoperative perilesional injection of repository steroid.
Topics: Adolescent; Betamethasone; Child; Child, Preschool; Delayed-Action Preparations; Female; Follow-Up S | 1988 |
[Clinico-pathological evaluation of keloids treated with intralesional injections of corticoid].
Topics: Adolescent; Adult; Child; Child, Preschool; Collagen; Female; Humans; Injections; Keloid; Male; Midd | 1987 |
Implantation of human keloid into athymic mice.
Topics: Adult; Animals; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Humans; Keloid; Male; | 1987 |
Linear atrophy following intralesional steroid injections.
Topics: Adolescent; Adult; Atrophy; Female; Humans; Injections; Keloid; Male; Skin; Triamcinolone Acetonide | 1988 |
The immunological aspects of keloid tumor formation.
Topics: Adult; Antigen-Antibody Complex; Complement C3; Complement C4; Humans; Keloid; Lasers; Nephelometry | 1988 |
[Treatment of post-burn scars].
Topics: Burns; Cicatrix; Combined Modality Therapy; Humans; Keloid | 1988 |
Scar and keloidlike lesions in progeria. An electron-microscopic and immunohistochemical study.
Topics: Biopsy; Child, Preschool; Cicatrix; Female; Humans; Immunohistochemistry; Keloid; Microscopy, Electr | 1988 |
Reduced growth-factor requirement of keloid-derived fibroblasts may account for tumor growth.
Topics: Adult; Cell Division; Cells, Cultured; Cicatrix; DNA Replication; Fibroblasts; Humans; Infant, Newbo | 1988 |
Treatment of keloids with strontium 90 beta rays.
Topics: Adolescent; Adult; Aged; Beta Particles; Child; Child, Preschool; Combined Modality Therapy; Evaluat | 1987 |
[Dentaflex compression plates in the treatment and prevention of hypertrophic scars and keloids following burns].
Topics: Burns; Cicatrix; Evaluation Studies as Topic; Humans; Keloid; Occlusive Dressings; Ointments; Silico | 1987 |
[Prospects in oral pathology and surgery of the masticatory system].
Topics: Bone Diseases; Humans; Keloid; Neoplasms; Oral Surgical Procedures, Preprosthetic; Osteoma, Osteoid; | 1986 |
[Cervical cutaneous expansion: treatment of post-burn keloids. Personal cases].
Topics: Burns; Child; Humans; Keloid; Male; Neck; Surgery, Plastic | 1987 |
[Late complications following ear piercing--therapeutic possibilities].
Topics: Ear, External; Female; Humans; Keloid; Postoperative Complications; Surgical Flaps; Suture Technique | 1986 |
[Treatment possibilities of keloid in the ENT area with special reference to anthelixplasty].
Topics: Combined Modality Therapy; Ear Diseases; Ear, External; Humans; Keloid; Recurrence; Surgical Flaps; | 1986 |
Mast cells in human keloid, small intestine, and lung by an immunoperoxidase technique using a murine monoclonal antibody against tryptase.
Topics: Animals; Antibodies, Monoclonal; Humans; Intestine, Small; Keloid; Lung; Mast Cells; Mice; Peptide H | 1986 |
Pseudofolliculitis barbae with keloids.
Topics: Adult; Folliculitis; Humans; Keloid; Male; Peptostreptococcus; Skin Transplantation; Streptococcal I | 1986 |
[Rubinstein-Taybi syndrome with multiple keloids].
Topics: Abnormalities, Multiple; Adolescent; Female; Humans; Keloid; Pedigree; Phenotype; Rubinstein-Taybi S | 1986 |
[Course of the wound process following the cryodestructon of hypertrophic and keloid scars].
Topics: Burns; Cicatrix; Cryosurgery; Dermatologic Surgical Procedures; Humans; Hypertrophy; Keloid; Postope | 1987 |
[Late results of the treatment and rehabilitation of children who suffered burns at an early age].
Topics: Burns; Child, Preschool; Cicatrix; Contracture; Follow-Up Studies; Humans; Infant; Keloid; Time Fact | 1987 |
A protocol for the treatment of hypertrophic scars and keloids.
Topics: Adrenal Cortex Hormones; Cicatrix; Combined Modality Therapy; Humans; Hypertrophy; Keloid; Pressure; | 1987 |
Laser therapy of the skin. A review of principles and applications.
Topics: Hemangioma; Humans; Keloid; Laser Therapy; Nevus, Pigmented; Photochemotherapy; Skin Diseases; Skin | 1987 |
Wide spread scars, hypertrophic scars, and keloids.
Topics: Adult; Child; Cicatrix; Glucocorticoids; Humans; Hypertrophy; Keloid; Pressure; Skin | 1987 |
Allergic dermal contact dermatitis due to gold earrings.
Topics: Adult; Dermatitis, Contact; Ear, External; Female; Gold; Humans; Keloid; Middle Aged; Skin Tests | 1987 |
Preliminary report on use of the neodymium-YAG laser in plastic surgery.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Epistaxis; Female; Granuloma; Hemangioma; Humans; | 1987 |
[Conservative therapy of scars and wrinkles].
Topics: Administration, Topical; Anti-Inflammatory Agents; Cicatrix; Combined Modality Therapy; Cryosurgery; | 1987 |
Collagen gene expression in keloids: analysis of collagen metabolism and type I, III, IV, and V procollagen mRNAs in keloid tissue and keloid fibroblast cultures.
Topics: Cells, Cultured; Collagen; Fibroblasts; Gene Expression Regulation; Humans; Keloid; Procollagen; RNA | 1987 |
Keloid scars as a result of CO2 laser for molluscum contagiosum.
Topics: Adult; Cicatrix; Female; Genital Diseases, Female; Humans; Keloid; Laser Therapy; Molluscum Contagio | 1987 |
The practical application of lasers: a first-hand account.
Topics: Humans; Keloid; Laser Therapy; Operating Room Nursing; Patient Education as Topic | 1986 |
Scars: formation and effects.
Topics: Adolescent; Africa; Child; Cicatrix; Culture; Female; Humans; Keloid; Male; Surgery, Plastic | 1986 |
[Treatment of hypertrophic and keloid-like scars by continuous compression].
Topics: Cicatrix; Humans; Hypertrophy; Keloid; Pressure | 1987 |
[Postoperative therapy of keloids. Preliminary results in our cases].
Topics: Adolescent; Adult; Child; Combined Modality Therapy; Female; Humans; Keloid; Male; Middle Aged | 1987 |
[Treatment of keloids by cryotherapy].
Topics: Cryosurgery; Humans; Keloid; Wound Healing | 1987 |
Tissue expanders in reconstructive surgery.
Topics: Adolescent; Adult; Breast; Child; Cicatrix; Female; Humans; Keloid; Male; Middle Aged; Surgery, Plas | 1987 |
Laser controversy.
Topics: Ear, External; Humans; Keloid; Laser Therapy | 1986 |
Postsurgical acrylic ear splints for keloids.
Topics: Acrylates; Adult; Ear Diseases; Ear, External; Female; Humans; Keloid; Postoperative Care; Splints | 1986 |
Cryosurgical treatment of a large keloid.
Topics: Adult; Cryosurgery; Head; Humans; Keloid; Male | 1986 |
[Studies on superoxide dismutase in human skin (4). Contents of superoxide dismutase and lipid peroxide in keloid, hypertrophic scar and scar].
Topics: Cicatrix; Humans; Keloid; Lipid Peroxides; Malonates; Malondialdehyde; Skin; Superoxide Dismutase | 1986 |
Corneal keloids.
Topics: Adult; Aged; Corneal Diseases; Corneal Ulcer; Humans; Keloid; Male; Middle Aged | 1986 |
Pseudomelanoma following treatment with surgical excision and intralesional triamcinolone acetonide to prevent keloid formation.
Topics: Adult; Female; Humans; Keloid; Melanoma; Neoplasm Recurrence, Local; Nevus, Pigmented; Skin Neoplasm | 1986 |
Retinoid effects on fibroblast proliferation and collagen synthesis in vitro and on fibrotic disease in vivo.
Topics: Cell Division; Cells, Cultured; Cicatrix; Collagen; Fibroblasts; Humans; In Vitro Techniques; Keloid | 1986 |
Suppurative keloidosis in a black woman.
Topics: Female; Humans; Keloid; Middle Aged; Skin; Suppuration | 1986 |
[Indications for free transplants for scar correction in the area of the head and neck].
Topics: Adult; Burns; Carcinoma, Squamous Cell; Cicatrix; Eye Injuries; Face; Facial Injuries; Facial Neopla | 1986 |
[Keloid scars as a sequel of herpes zoster].
Topics: Aged; Female; Herpes Zoster; Humans; Keloid | 1986 |
[Treatment of keloid].
Topics: Adrenal Cortex Hormones; Cryosurgery; Humans; Keloid; Laser Therapy | 1986 |
New technique for intralesional steroid injections.
Topics: Child, Preschool; Cicatrix; Humans; Hypertrophy; Injections; Keloid; Steroids | 1987 |
[Effect of retinoic acid on keloid scars].
Topics: Female; Humans; Keloid; Male; Tretinoin | 1985 |
Altered steady-state ratio of type I/III procollagen mRNAs correlates with selectively increased type I procollagen biosynthesis in cultured keloid fibroblasts.
Topics: Cells, Cultured; Fibroblasts; Gene Expression Regulation; Genes; Humans; Keloid; Procollagen; RNA, M | 1985 |
Facial keloids: an update on dental considerations and new management techniques.
Topics: Face; Humans; Keloid; Recurrence | 1985 |
Auricular compression stent.
Topics: Ear Diseases; Ear, External; Equipment Design; Humans; Keloid; Splints | 1985 |
Methyl methacrylate stent for prevention of postexcisional recurrent ear keloid.
Topics: Ear Diseases; Ear, External; Equipment Design; Humans; Keloid; Methylmethacrylates; Recurrence; Spli | 1985 |
[Evaluation of various operative methods in relation to the prevention of failures in scar correction].
Topics: Cicatrix; Clothing; Humans; Keloid; Postoperative Care; Postoperative Complications; Suture Techniqu | 1985 |
Plastic and reconstructive surgery. Scars, hypertrophic scars, and keloids.
Topics: Cicatrix; Female; Humans; Keloid; Male; Surgery, Plastic; Tattooing; Wound Healing | 1985 |
Scleroderma presenting with multiple keloids.
Topics: Adolescent; Female; Humans; Keloid; Scleroderma, Localized | 1985 |
Treatment of earlobe keloids with carbon dioxide laser excision: a report of 16 cases.
Topics: Adolescent; Adult; Aged; Carbon Dioxide; Child; Combined Modality Therapy; Ear, External; Female; Hu | 1985 |
Laser-tissue interactions and their clinical applications.
Topics: Forecasting; Hematoporphyrin Photoradiation; Humans; Keloid; Laser Therapy; Melanoma; Nevus, Pigment | 1986 |
Treatment of recurrent earlobe keloids.
Topics: Adolescent; Adult; Child; Ear, External; Female; Flurandrenolone; Humans; Keloid; Male; Middle Aged; | 1986 |
[Treatment of keloids of the head and neck].
Topics: Combined Modality Therapy; Facial Dermatoses; Humans; Keloid | 1986 |
Treatment of keloids and hypertrophic scars with an argon laser.
Topics: Adolescent; Adult; Child; Cicatrix; Female; Humans; Keloid; Laser Therapy; Male; Middle Aged | 1986 |
[Physiotherapy in the complex treatment of post-burn keloid scars].
Topics: Burns; Combined Modality Therapy; Humans; Keloid | 1985 |
[Triamcinolone acetonide in the treatment of hypertrophic and keloid scars].
Topics: Cicatrix; Humans; Hypertrophy; Injections, Subcutaneous; Keloid; Triamcinolone Acetonide | 1985 |
[Combination treatment of keloid scars of the skin].
Topics: Adolescent; Adult; Child; Child, Preschool; Combined Modality Therapy; Cryosurgery; Humans; Keloid; | 1985 |
Retinoid modulation of connective tissue metabolism in keloid fibroblast cultures.
Topics: Cells, Cultured; Collagen; Connective Tissue; Connective Tissue Cells; Dose-Response Relationship, D | 1985 |
Biochemical composition of the connective tissue in keloids and analysis of collagen metabolism in keloid fibroblast cultures.
Topics: Adult; Cells, Cultured; Collagen; Connective Tissue; Female; Fibroblasts; Humans; Keloid; Middle Age | 1985 |
Studies on human scar tissue proteoglycans.
Topics: Chromatography, DEAE-Cellulose; Cicatrix; Humans; Hypertrophy; Keloid; Proteoglycans; Skin | 1985 |
Wave-length dispersive microprobe analysis of coated samples of bulk tissues.
Topics: Animals; Antlers; Cicatrix; Electron Probe Microanalysis; Horns; Humans; Keloid; Microscopy, Electro | 1985 |
[Cryodestruction of keloids].
Topics: Cryosurgery; Humans; Keloid | 1985 |
The use of athymic nude mice for the study of human keloids.
Topics: Animals; Disease Models, Animal; Glycosaminoglycans; Humans; Keloid; Mice; Mice, Nude | 1985 |
[Calcifications in a scar keloid].
Topics: Adult; Calcinosis; Chin; Cicatrix; Female; Humans; Keloid | 1985 |
Myofibroblasts in fibromatoses. An electron microscopic study.
Topics: Adolescent; Adult; Cicatrix; Female; Fibroblasts; Fibroma; Humans; Infant, Newborn; Keloid; Male; Mi | 1985 |
The behaviour of presternal scars in a fair-skinned population.
Topics: Adolescent; Adult; Aged; Cardiac Surgical Procedures; Child; Cicatrix; Dermatologic Surgical Procedu | 1985 |
[The use of lasers in medicine with special reference to dermatology].
Topics: Bowen's Disease; Carcinoma, Basal Cell; Condylomata Acuminata; Eye Protective Devices; Humans; Keloi | 1985 |
[Flattening of hypertrophic scars by punctiform argon ion laser coagulation in several sessions].
Topics: Adult; Argon; Humans; Keloid; Laser Therapy; Lasers; Male | 1985 |
[Treatment of hypertrophic and cheloid scars in children].
Topics: Child; Child, Preschool; Cicatrix; Cryosurgery; Humans; Hypertrophy; Infant; Keloid; Male | 1985 |
[Treatment of keloid scars developing after BCG vaccination in children and adolescents].
Topics: Adolescent; BCG Vaccine; Child; Drug Therapy, Combination; Humans; Keloid; Vaccination | 1985 |
[Experience in the treatment of spontaneous keloid with dibunol].
Topics: Butylated Hydroxytoluene; Combined Modality Therapy; Female; Humans; Keloid; Middle Aged | 1985 |
Total facial paralysis following keloid removal.
Topics: Facial Paralysis; Humans; Keloid; Male; Postoperative Complications | 1985 |
[Studies on explanted keloid tissue].
Topics: Adrenal Glands; Animals; Ascorbic Acid; Chick Embryo; Culture Techniques; Humans; Hyaluronoglucosami | 1971 |
Electron microscopic study of lobomycosis (Loboa loboi).
Topics: Animals; Biopsy; Blastomyces; Blastomycosis; Carbohydrate Metabolism; Cytoplasmic Granules; Dermatom | 1972 |
The mast cell in hypertrophic scars.
Topics: Biopsy; Burns; Child; Cicatrix; Hot Temperature; Humans; Hypertrophy; Keloid; Mast Cells; Microscopy | 1972 |
Kenacort A in the treatment of hypertrophic scars and keloids in children.
Topics: Adolescent; Burns; Child; Child, Preschool; Cicatrix; Humans; Hypertrophy; Infant; Keloid; Suspensio | 1973 |
B.C.G. vaccination by multiple puncture method.
Topics: Adolescent; BCG Vaccine; Child; Congresses as Topic; Humans; Japan; Keloid; Methods; Tuberculin Test | 1972 |
Post vaccination keloid.
Topics: Adolescent; Age Factors; BCG Vaccine; Child; Congresses as Topic; Female; Humans; Keloid; Male; Prur | 1972 |
Fibrous xanthomas of the conjunctiva.
Topics: Adult; Arthritis, Rheumatoid; Biopsy; Conjunctiva; Eye Diseases; Female; Histiocytes; Humans; Keloid | 1968 |
The histoenzymological pattern of the keloids and hypertrophic scars.
Topics: Cicatrix; Diagnosis, Differential; Humans; Hypertrophy; Keloid | 1968 |
Congenital skin defects.
Topics: Anti-Infective Agents, Local; Birth Injuries; Dermatitis, Seborrheic; Diagnosis, Differential; Femal | 1968 |
Lobo's disease involving the skin of a dolphin.
Topics: Animals; Blastomycosis; Dermatomycoses; Dolphins; Female; Keloid | 1974 |
[Multiple keloids following "toxic epidermal necrolysis" (Lyell)].
Topics: Drug Eruptions; Female; Humans; Keloid; Middle Aged; Stevens-Johnson Syndrome; Sulfamethoxypyridazin | 1966 |
Autotransplantation of keloid in man.
Topics: Abdominal Muscles; Adult; Child; Female; Follow-Up Studies; Humans; Keloid; Male; Neoplasm Transplan | 1967 |
[Care of skin injuries of the hand].
Topics: Bone Transplantation; Burns; Child; Cicatrix; Dermatologic Surgical Procedures; Female; Hand Injurie | 1967 |
[Comparative study of water, collagen and mucopolysaccharids contents in healthy human skin, in normal and keloid cicatrix].
Topics: Cicatrix; Collagen; Glycosaminoglycans; Humans; Keloid; Skin; Water | 1970 |
Multiple keloids.
Topics: Acne Vulgaris; Adult; Aged; Black or African American; Female; Humans; Keloid; Male; Middle Aged; Sk | 1971 |
Cryosurgical therapy of benign lesions of the skin and mucous membranes.
Topics: Adult; Aged; Cryosurgery; Cysts; Dermatitis, Seborrheic; Epistaxis; Gingival Neoplasms; Hemangioma; | 1971 |
[Dermatologic counterindications for protective vaccination in the GDR].
Topics: Adult; Cholera Vaccines; Diphtheria Toxoid; Drug Eruptions; Female; Humans; Infant; Influenza Vaccin | 1971 |
[Reaction forms of the connective tissue following pathogenic influences].
Topics: Cicatrix; Collagen; Collagen Diseases; Connective Tissue; Connective Tissue Cells; Elastic Tissue; E | 1972 |
[Open-air management of burns and scaldings from the orthopedic viewpoint].
Topics: Age Factors; Burns; Burns, Electric; Child; Child, Preschool; Hot Temperature; Humans; Humidity; Inf | 1972 |
Minor surgery for benign and malignant facial lesions.
Topics: Acne Vulgaris; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cicatrix; Cortisone; Curettage; Cyst | 1974 |
The degradation of mature collagen: a laboratory study.
Topics: Animals; Cicatrix; Collagen; Connective Tissue; Hydrocortisone; In Vitro Techniques; Keloid; Microbi | 1967 |
Intracellular collagen fibers. In human mesenchymal tumors and inflammatory states.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Collagen; Female; Fibroma; Fibrosarcoma; Histiocyt | 1967 |
[Radiotherapy in childhood].
Topics: Bone Neoplasms; Brain Neoplasms; Child; Hodgkin Disease; Humans; Keloid; Kidney Neoplasms; Leukemia; | 1968 |
[Angiographic and scintigraphic findings on the kidney in Pringle's syndrome (adenoma sebaceum)].
Topics: Adenoma; Adult; Angiography; Diagnosis, Differential; Hand; Head; Histiocytoma, Benign Fibrous; Huma | 1971 |
Collagenase activity in cutaneous scars.
Topics: Carbon Radioisotopes; Cicatrix; Collagen; Culture Techniques; Humans; Hypertrophy; Keloid; Microbial | 1973 |
Histamine and collagen synthesis in keloid and hypertrophic scar.
Topics: Cicatrix; Collagen; Histamine; Humans; Keloid; Procollagen-Proline Dioxygenase | 1972 |
Collagen degradation in cultured keloid and hypertrophic scar tissue.
Topics: Adolescent; Adult; Aged; Carbon Radioisotopes; Child; Child, Preschool; Cicatrix; Collagen; Culture | 1973 |
Tumours of the soft (mesenchymal) tissues.
Topics: Animals; Animals, Domestic; Calcinosis; Cats; Dogs; Histiocytoma, Benign Fibrous; Horses; Keloid; Li | 1974 |
Histochemistry of hypertrophic scars and keloids.
Topics: Acid Phosphatase; Alkaline Phosphatase; Cicatrix; Glucuronidase; Histocytochemistry; Humans; Hypertr | 1974 |
Collagen synthesis in keloid and hypertrophic scar following intralesional use of triamcinolone.
Topics: Cicatrix; Collagen; Ear, External; Humans; In Vitro Techniques; Keloid; Procollagen-Proline Dioxygen | 1973 |
A new probably X-linked inherited syndrome: congenital muscular torticollis, multiple keloids cryptorchidism and renal dysplasia.
Topics: Adolescent; Adult; Aged; Child; Connective Tissue; Cryptorchidism; Female; Humans; Keloid; Kidney Fa | 1968 |
Editorial: Keloids and x-rays.
Topics: Adrenal Cortex Hormones; Humans; Keloid; Radiotherapy Dosage | 1974 |
[Cryotherapy in plastic surgery].
Topics: Cicatrix; Cryosurgery; Facial Neoplasms; Humans; Keloid; Nevus, Pigmented; Skin Neoplasms; Surgery, | 1974 |
[Treatment of dermatoses in children with synalar-forte, synalar-gel and metosyn].
Topics: Acetates; Adolescent; Child; Child, Preschool; Drug Evaluation; Eczema; Fluocinolone Acetonide; Gran | 1974 |
[Pathogenesis of keloid scars].
Topics: 11-Hydroxycorticosteroids; Burns; Humans; Keloid; Wound Healing | 1974 |
Keloids in Ibadan.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Ear, External; Female; Humans; Keloid; Male | 1974 |
[Treatment of late sequelae of severe burns caused by inflammable and incendiary agents from the point of view of a dermatologist].
Topics: Administration, Topical; Anti-Inflammatory Agents; Burns; Cicatrix; Glucocorticoids; Humans; Keloid; | 1974 |
[Keloid and smallpox vaccination].
Topics: Humans; Injections, Subcutaneous; Keloid; Shoulder; Smallpox Vaccine; Vaccination | 1974 |
[Sodium nitro-prusside as a hypotensive agent during surgical operations (author's transl)].
Topics: Blood Pressure; Brain Neoplasms; Cardiac Volume; Female; Ferricyanides; Hemangioma; Humans; Hypotens | 1974 |
Vitriolage.
Topics: Burns, Chemical; Cicatrix; Face; Facial Injuries; Humans; Keloid; Male; Neck; Sulfuric Acids | 1974 |
[Recurrent keloid in the pedicle skin graft of the concha auriculae].
Topics: Adult; Ear, External; Frostbite; Humans; Keloid; Male; Recurrence | 1974 |
Penicillamine in the treatment of morphoea and keloid in children.
Topics: Child; Female; Humans; Keloid; Male; Penicillamine; Scleroderma, Localized | 1974 |
[Formation of keloid scars after intradermal antituberculosis vaccination].
Topics: BCG Vaccine; Cicatrix; Female; Humans; Injections, Intradermal; Keloid; Male; Puberty; Sex Factors; | 1974 |
[Formation of keloid scars at the site of administration BCG vaccine in children and adolescents revaccinated with BCG by intravenous method].
Topics: BCG Vaccine; Cicatrix; Female; Humans; Immunization, Secondary; Injections, Intravenous; Keloid; Mal | 1974 |
Eradication of large auricular keloids by excision, skin grafting, and intradermal injection of triamcinolone acetonide solution. Case report.
Topics: Ear Deformities, Acquired; Humans; Injections, Intradermal; Keloid; Male; Skin Transplantation; Tran | 1972 |
[Spindle cell epithelioma on an old keloid of the upper extremity after a burn. Functional restoration].
Topics: Burns; Carcinoma, Squamous Cell; Cicatrix; Forearm; Humans; Keloid; Male; Middle Aged; Skin Neoplasm | 1972 |
[Treatment of keloid scars by subtotal excision and graft (apropos of l4 cases)].
Topics: Cicatrix; Humans; Keloid; Methods; Skin Transplantation; Transplantation, Autologous | 1972 |
The use of homografts in keloids.
Topics: Cicatrix; Female; Graft Rejection; Humans; Keloid; Methods; Recurrence; Refrigeration; Skin Transpla | 1973 |
[Treatment with lemon juice in the prevention of recurrences of keloid].
Topics: Adolescent; Ascorbic Acid; Child; Citrates; Citrus; Female; Humans; Keloid; Male; Postoperative Care | 1973 |
Yoruban contributions to the literature on keloids.
Topics: History, Ancient; Humans; Keloid; Medicine in Literature; Medicine in the Arts; Medicine, Traditiona | 1973 |
[Scars and scar revision].
Topics: Cicatrix; Humans; Keloid; Skin Transplantation; Surgery, Plastic; Transplantation, Autologous; Wound | 1973 |
Revision of scars of the head and neck.
Topics: Cicatrix; Dermabrasion; Dermatologic Surgical Procedures; Head; Humans; Hypertrophy; Keloid; Methods | 1974 |
Revision techniques in otoplasty. Evaluation and management.
Topics: Adolescent; Adult; Child; Child, Preschool; Ear Diseases; Ear, External; Evaluation Studies as Topic | 1974 |
Surgery of the external ear.
Topics: Age Factors; Amputation, Surgical; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cartilage; Child | 1974 |
[Suture techniques, scars and their correction (author's transl)].
Topics: Cicatrix; Humans; Keloid; Methods; Postoperative Complications; Prednisolone; Surgery, Plastic; Surg | 1974 |
Surgical correction of severe cicatricial ectropion caused by chickenpox.
Topics: Chickenpox; Child; Ectropion; Eyelids; Humans; Immunologic Deficiency Syndromes; Keloid; Male; Skin | 1974 |
[Prevention and treatment of keloid scars after cutiplastic operations in children].
Topics: Child; Elephantiasis; Follow-Up Studies; Humans; Keloid; Leg; Lymphedema; Male; Skin Transplantation | 1974 |
Keloids in the African.
Topics: Adolescent; Adult; Africa; Black People; Child; Child, Preschool; Disease Susceptibility; Endocrine | 1974 |
Technical considerations in the surgical management of pectus excavatum and carinatum.
Topics: Adolescent; Adult; Cartilage; Child; Child, Preschool; Drainage; Female; Follow-Up Studies; Funnel C | 1974 |
[The influence of magnetic fields in wound healing (author's transl)].
Topics: Adult; Burns; Electromagnetic Phenomena; Female; Humans; Keloid; Magnetics; Male; Microsurgery; Nerv | 1974 |
[Surgical treatment of gigantic elephantiasis of the lower extremities in children].
Topics: Administration, Topical; Anti-Inflammatory Agents; Atmosphere Exposure Chambers; Child; Child, Presc | 1974 |
Damages awarded after removal of broken catheter.
Topics: Adult; Arm; California; Catheterization; Female; Foreign Bodies; Humans; Jurisprudence; Keloid; Malp | 1973 |
[Monstrous keloid].
Topics: Adolescent; Chickenpox; Female; Humans; Keloid; Postoperative Care | 1972 |
[Anatomo-clinical study of 15 keloid scars].
Topics: Adolescent; Burns; Child; Diagnosis, Differential; Female; Humans; Keloid; Male; Sex Factors; Skin; | 1972 |
[Cicatrization and scars in the cervicofacial area].
Topics: Atrophy; Biomechanical Phenomena; Burns; Cicatrix; Facial Injuries; Granuloma; Humans; Hypertrophy; | 1972 |
[Gynecology in the country of the sewn women].
Topics: Adolescent; Adult; Ceremonial Behavior; Child; Circumcision, Male; Clitoris; Coitus; Culture; Cysts; | 1972 |
[Neuraminic acid in scar tissue and biological fluids in patients with keloids].
Topics: Burns; Humans; Keloid; Neuraminic Acids; Pyrogens | 1972 |
The pitfall of surgical excision of vaccination scars in the deltoid area.
Topics: Adult; Child; Cicatrix; Female; Humans; Keloid; Male; Smallpox Vaccine; Vaccination | 1973 |
Radiotherapy for keloid treatment.
Topics: Adolescent; Adult; Black People; Evaluation Studies as Topic; Female; Humans; Keloid; Male; Middle A | 1973 |
Keloids: reassessment of irradiation therapy.
Topics: Humans; Keloid; Methods; Postoperative Complications; Steroids | 1973 |
Is plastic surgery effective in the rehabilitation of deformed delinquent adolescents?
Topics: Adolescent; Adult; Body Image; Burns; Child; Cicatrix; Cleft Lip; Ear, External; Facial Paralysis; F | 1973 |
[Treatment of cheloids and cheloid scars with intralesional corticoid injections].
Topics: Humans; Hydrocortisone; Injections; Keloid | 1973 |
[Kenacort A treatment of hypertrophic scars and keloids in children].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Cicatrix; Evaluation Studies as Topic; Humans; Inf | 1973 |
[2 cases of keloid scar development following BCG vaccination].
Topics: BCG Vaccine; Child; Humans; Keloid; Recurrence | 1973 |
[Elephantiasis (lymphedema) of the extremities of mechanical origin].
Topics: Adolescent; Adult; Aneurysm; Arm; Arm Injuries; Cicatrix; Erysipelas; Female; Femoral Artery; Femora | 1973 |
A sensitive microassay for prolyl hydroxylase: activity in normal and psoriatic skin.
Topics: Animals; Ascorbic Acid; Catalase; Chick Embryo; Collagen; Dithiothreitol; Humans; Iron; Keloid; Keto | 1973 |
[The use of benzene adhesives in the closure of wounds].
Topics: Benzene Derivatives; Cicatrix; Humans; Inflammation; Keloid; Surgical Procedures, Operative; Tissue | 1973 |
[Treatment of some dermatoses by the intradermal injections of a 10 percent solution of quingamine].
Topics: Adult; Chloroquine; Chronic Disease; Female; Humans; Injections, Intradermal; Keloid; Lupus Erythema | 1973 |
Correction of keloids and finger contractures in burn patients.
Topics: Burns; Child, Preschool; Cicatrix; Clothing; Contracture; Elasticity; Face; Fingers; Humans; Keloid; | 1973 |
[Formation of keloids after electroepilation].
Topics: Adult; Electricity; Hair Removal; Humans; Keloid; Male | 1973 |
Radiotherapy in the treatment of keloids in East Africa.
Topics: Africa, Eastern; Humans; Keloid | 1973 |
[Electrophoresis of apifor, a new bee venom preparation, in postburn cicatrices].
Topics: Adolescent; Adult; Bees; Biological Products; Burns; Child; Cicatrix; Electrophoresis; Humans; Keloi | 1973 |
[Proceedings: Unusual tumors of the ear and mandible].
Topics: Ear Neoplasms; Humans; Keloid; Mandibular Neoplasms; Motion Pictures | 1973 |
[On the use of dimethyl sulphoxide (DMSO) in radiation therapy (author's transl)].
Topics: Adolescent; Adult; Child, Preschool; Dimethyl Sulfoxide; Female; Humans; Keloid; Male; Middle Aged; | 1973 |
An interesting case of multiple keloids.
Topics: Echinococcosis; Female; Humans; Keloid; Middle Aged; Splenic Diseases; Sweating | 1973 |
Study of 1,000 patients with keloids in South India.
Topics: ABO Blood-Group System; Adolescent; Adult; Age Factors; BCG Vaccine; Child; Ear, External; Female; H | 1974 |
Nasal syringadenomas.
Topics: Adenoma; Diagnosis, Differential; Female; Humans; Keloid; Male; Middle Aged; Nonodontogenic Cysts; N | 1974 |
Perilymphatic atrophy of the skin. A side effect of topical corticosteroid injection therapy.
Topics: Atrophy; Child; Female; Humans; Keloid; Lymphatic System; Skin Diseases; Triamcinolone Acetonide | 1974 |
Cryosurgery for hypertrophic scars and keloids. A preliminary report.
Topics: Cicatrix; Collagen; Cryosurgery; Humans; Keloid | 1974 |
Bilateral earlobe keloids.
Topics: Adolescent; Adult; Child; Child, Preschool; Ear Diseases; Ear, External; Female; Humans; Keloid; Mid | 1974 |
The problem stoma.
Topics: Cicatrix; Humans; Keloid; Laryngectomy; Methods; Postoperative Complications; Silicone Elastomers; T | 1974 |
An experience in treating five hundred and one patients with keloids.
Topics: Adolescent; Adult; Child; Child, Preschool; Ethnicity; Female; Humans; Infant; Infant, Newborn; Kelo | 1974 |
[Treatment of keloids with triamcinolon acetonide (author's transl)].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Injections, Intramuscular; Keloid; Male; | 1974 |
Dermatofibrosarcoma protuberans or keloid--a warning. Case report.
Topics: Adult; Diagnosis, Differential; Diagnostic Errors; Female; Fibrosarcoma; Humans; Keloid; Skin; Skin | 1974 |
Radiation therapy in the treatment of keloids in East Africa.
Topics: Follow-Up Studies; Humans; Keloid; Neoplasm Recurrence, Local; Radiotherapy Dosage; Time Factors | 1974 |
Button compression for keloids of the lobule.
Topics: Bandages; Ear, External; Humans; Keloid; Male; Pressure; Splints | 1974 |
Aspects of plastic surgery. Scars.
Topics: Cicatrix; Collagen; Contracture; Humans; Hypertrophy; Keloid; Methods; Surgery, Plastic | 1974 |
A note on the cultivation of the aetiological agent of Jorge Lôbo's disease in 199 T.C. medium containing phytohaemagglutinin. Preliminary report.
Topics: Blastomyces; Blastomycosis; Culture Media; Humans; Keloid; Lectins; Syndrome | 1974 |
[Tension reducing incision and grafting for scar contracture at the joints. 1].
Topics: Adult; Child; Child, Preschool; Cicatrix; Contracture; Female; Humans; Infant; Joints; Keloid; Male; | 1967 |
[The unsatisfactory skin scar: Punishment or destiny?].
Topics: Black People; Cicatrix; Granulation Tissue; Humans; Hypertrophy; Keloid; Postoperative Care; Prognos | 1967 |
Skin grafting by magnetism.
Topics: Adolescent; Female; Humans; Keloid; Magnetics; Methods; Skin Transplantation; Surgery, Plastic; Tran | 1968 |
Removal of a massive facial keloid and subsequent skin-grafting by magnetism.
Topics: Adult; Face; Humans; Keloid; Magnetics; Male; Skin Transplantation; Transplantation, Autologous | 1968 |
[Defect grafting following damage to the skin and surroundings in the facio-cervical area].
Topics: Adolescent; Aged; Burns; Child, Preschool; Cicatrix; Ectropion; Facial Injuries; Female; Humans; Kel | 1969 |
Unexpected postoperative problems in skin grafting.
Topics: Cellulitis; Cicatrix; Contracture; Hematoma; Humans; Infections; Keloid; Necrosis; Postoperative Com | 1970 |
[Reticulated homotransplant (from mother to child) in the treatment of burned children and in the prevention of keloids secondary to burns].
Topics: Burns; Female; Humans; Infant; Keloid; Male; Skin Transplantation; Tissue Donors; Transplantation, H | 1969 |
[Use of steri-strips to prevent the elargement of cicatrix].
Topics: Humans; Keloid; Suture Techniques | 1970 |
Reconstruction of midline skin defects of the nose.
Topics: Adult; Aged; Carcinoma, Basal Cell; Cicatrix; Facial Dermatoses; Female; Hodgkin Disease; Humans; Ke | 1969 |
Cutaneous scars and cosmetic surgery.
Topics: Adrenal Cortex Hormones; Ascorbic Acid; Bandages; Breast; Cicatrix; Eyelids; Face; Humans; Keloid; N | 1971 |
[Significance of the tissue adhesives in keloid surgery].
Topics: Animals; Cicatrix; Dogs; Humans; Keloid; Methods; Skin Transplantation; Suture Techniques; Sutures; | 1971 |
Management of keloids by surgical excision and local injections of a steroid.
Topics: Adolescent; Adult; Child; Epinephrine; Female; Humans; Injections, Subcutaneous; Keloid; Lidocaine; | 1971 |
[Full skin graft strips in plastic surgery to cover scar keloids of the hands following burns].
Topics: Adult; Burns; Cicatrix; Dermatologic Surgical Procedures; Finger Injuries; Hand Injuries; Humans; Ke | 1970 |
[Keloidal blastomycosis associated with South American blastomycosis. Report of a case].
Topics: Amphotericin B; Blastomycosis; Blood Protein Electrophoresis; Humans; Immunodiffusion; Immunoelectro | 1967 |
[Treatment of keloids with electrons accelerated by the betatron].
Topics: Electrons; Humans; Keloid; Radiotherapy, High-Energy; Strontium Isotopes; Yttrium Isotopes | 1968 |
[Degree of collagen maturation in normal and keloid cicatrix].
Topics: Aging; Cicatrix; Collagen; Humans; Hydroxyproline; Keloid; Skin | 1970 |
Keloid scars. Analysis of 89 patients.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Keloid; M | 1970 |
[Scar ossifications following laparotomy and their x-ray images].
Topics: Adult; Cicatrix; Humans; Keloid; Laparotomy; Male; Middle Aged; Ossification, Heterotopic; Postopera | 1970 |
[Observations from a Saigon hospital for reconstructive pediatric surgery].
Topics: Anesthesiology; Burns; Child; Child Health Services; Humans; Keloid; Mouth Abnormalities; Noma; Preo | 1972 |
Corneal keloids.
Topics: Cornea; Corneal Injuries; Eye Diseases; Eye Injuries; Humans; Infant; Keloid; Male; Middle Aged | 1972 |
The chemical removal of tattoos.
Topics: Humans; Keloid; Methods; Outpatient Clinics, Hospital; Postoperative Care; Silver Nitrate; Tannins; | 1972 |
Keloid of the ear lobe.
Topics: Adolescent; Adult; Black People; Child; Ear Diseases; Ear, External; Female; Follow-Up Studies; Huma | 1972 |
[Method of occlusive dressing using dextran sulfate ointment for prevention of postoperative excessive scar formation].
Topics: Dextrans; Humans; Keloid; Ointments; Postoperative Complications; Sulfates | 1972 |
Coiffure keloids.
Topics: Adult; Female; Hair; Humans; Keloid; Scalp | 1972 |
[Fibromatoses-clinical aspects, morphology and classification].
Topics: Fibroma; Humans; Keloid | 1972 |
Correlation of keloid recurrence with completeness of local excision. A negative report.
Topics: Cicatrix; Humans; Keloid; Methods; Postoperative Complications; Recurrence | 1972 |
[Malabsorptive scleroderma].
Topics: Adult; Autopsy; Biopsy; Celiac Disease; Diagnosis, Differential; Diarrhea; Digestive System; Female; | 1972 |
[Treatment of keloids].
Topics: Bandages; Glucocorticoids; Humans; Keloid | 1972 |
Current concepts in the management of keloids.
Topics: Age Factors; Humans; Injections, Jet; Keloid; Lidocaine; Racial Groups; Sex Factors; Triamcinolone | 1972 |
The chest keloid.
Topics: Adolescent; Adult; Biopsy; Electrocoagulation; Female; Freezing; Humans; Iatrogenic Disease; Keloid; | 1972 |
Keloids and ultrasound.
Topics: Adult; Biopsy; Burns; Humans; Keloid; Male; Middle Aged; Ultrasonic Therapy; Wounds and Injuries | 1971 |
[Pathologohistologic and histochemical characteristics of keloids].
Topics: Adolescent; Adult; Histocytochemistry; Humans; Keloid; Skin | 1971 |
Alpha-naphthyl acid phosphatase activity in normal human skin and keloids.
Topics: Acid Phosphatase; Fluorometry; Histocytochemistry; Humans; Keloid; Keratins; Lysosomes; Naphthalenes | 1971 |
[Case report on the keloid problem in otorhinolaryngology].
Topics: Humans; Keloid; Otorhinolaryngologic Diseases | 1971 |
Collagen synthesis in human keloid and hypertrophic scar.
Topics: Ascorbic Acid; Cicatrix; Collagen; Humans; Keloid; Mixed Function Oxygenases; Proline; Skin; Tritium | 1971 |
[Morphological and electron microscopic characteristics of resolving keloid scars after pyrogenal therapy].
Topics: Biopsy; Cicatrix; Humans; Keloid; Microscopy, Electron; Pyrogens; Skin | 1971 |
[Treating some pruritic dermatoses and keloid scars with a novocaine block with lidase].
Topics: Adolescent; Adult; Cicatrix; Female; Humans; Hyaluronoglucosaminidase; Keloid; Male; Middle Aged; Pr | 1971 |
[Hypertrophic cicatrix and keloid of the surgical wound].
Topics: Adolescent; Adult; Cicatrix; Female; Humans; Hypertrophy; Keloid; Male; Middle Aged; Postoperative C | 1971 |
[Keloid eruption following chickenpox].
Topics: Adolescent; Arm; Chickenpox; Female; Humans; Keloid; Shoulder; Thorax | 1971 |
Ehlers-Danlos syndrome.
Topics: Adult; Ehlers-Danlos Syndrome; Eyelid Diseases; Female; Humans; Intestinal Diseases; Joint Dislocati | 1971 |
[Surgical removal and immediate radiotherapy (iridium 192) in treatment of keloids. Preliminary note].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Iridium; Keloid; Male; Middle Aged; Radi | 1967 |
[Chronogical study on radiotherapy in children. 1. Benign tumors].
Topics: Child; Female; Hemangioma; Humans; Japan; Keloid; Male; Neoplasms; Sex Factors; Statistics as Topic; | 1969 |
Familial idiopathic gingival hyperplasia with keloid formation and ectodermal dysplasia.
Topics: Dentistry; Ectodermal Dysplasia; Gingival Hyperplasia; Keloid | 1967 |
Indications and contraindications for the use of DMSO in clinical dermatology.
Topics: Amyloidosis; Animals; Anura; Dimethyl Sulfoxide; Dogs; Eczema; Humans; Keloid; Keratosis; Lichen Pla | 1967 |
Keloids versus hypertropic scars.
Topics: Cicatrix; Diagnosis, Differential; Humans; Hypertrophy; Keloid; Triamcinolone Acetonide | 1968 |
Combined modalities in the treatment of keloids.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Keloid; Male | 1967 |
[Keloid cicatrices of the face].
Topics: Cicatrix; Face; Facial Neoplasms; Keloid; Precancerous Conditions | 1969 |
[Cicatrization and scars; classical notions; recent studies].
Topics: Cicatrix; Facial Injuries; Humans; Keloid; Wound Healing | 1971 |
[On an unusual localization of a keloid].
Topics: Adult; Female; Foot Diseases; Humans; Keloid; Knee | 1966 |
[Physiotherapeutic treatment of keloid scars of the skin].
Topics: Adolescent; Adult; Child; Child, Preschool; Electric Stimulation Therapy; Humans; Keloid; Middle Age | 1965 |
[Prevention of hypertrophic scars following burns in children].
Topics: Allantoin; Burns; Child; Child, Preschool; Heparin; Humans; Infant; Keloid; Male; Ointments; Pharmac | 1969 |
Early post-operative irradiation in the treatment of keloid scars.
Topics: Adult; Child; Female; Humans; Keloid; Male; Postoperative Complications; Skin Transplantation | 1965 |
Successful delayed small artery repair following fracture of the femur. Case report and historical review.
Topics: Angiography; Child; Femoral Artery; Femoral Fractures; Fracture Fixation; Gangrene; Humans; Keloid; | 1967 |
Direct histochemical demonstration of histamine in cutaneous mast cells: urticaria pigmentosa and keloids.
Topics: Aged; Aldehydes; Female; Histamine; Histocytochemistry; Humans; Keloid; Mast Cells; Methods; Microsc | 1969 |
Keloids in various races. A review of 175 cases.
Topics: Adult; Age Factors; Asian People; Female; Humans; Keloid; Malaysia; Male; Sex Factors; Triamcinolone | 1969 |
[Use of hyaluronidase in clinical practice].
Topics: Arthritis, Rheumatoid; Contracture; Humans; Hyaluronoglucosaminidase; Keloid; Sinusitis; Tuberculosi | 1969 |
[Our experience in the treatment of certain dermatoses with ultra-soft roentgen rays (Bucky rays)].
Topics: Adolescent; Adult; Cheilitis; Eczema; Female; Humans; Keloid; Lichen Planus; Male; Middle Aged; Neur | 1969 |
[Follow-up studies 1-5 years following surgery for prominent ears].
Topics: Cold Temperature; Ear Deformities, Acquired; Eczema; Humans; Keloid; Perceptual Disorders; Postopera | 1969 |
[Neurotization and innervation of the human scar-keloids].
Topics: Adult; Burns; Cicatrix; Female; Hand Injuries; Humans; Keloid; Middle Aged; Nerve Endings; Nerve Reg | 1969 |
Follicular occlusion triad.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Anemia; Cellulitis; Folliculitis; Humans; Immunog | 1970 |
[Treatment of keloids and hypertrophic scars with triamcinolone acetonide].
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix; Female; Humans; Infant; Injections, Subcutaneo | 1970 |
A follow-up study on the treatment of keloids with triamicinolone acetonide.
Topics: Adolescent; Adult; Aged; Atrophy; Child; Child, Preschool; Cicatrix; Female; Follow-Up Studies; Huma | 1970 |
Biologic basis for the treatment of keloids and hypertrophic scars.
Topics: Cicatrix; Collagen; Cortisone; Humans; Hypertrophy; Keloid; Models, Biological; Time Factors; Wound | 1970 |
Combined surgical and x-ray therapy of keloids.
Topics: Adult; Follow-Up Studies; Humans; Keloid | 1970 |
A clinical trial of flurandrenolone tape.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Flurandrenolone; Humans; Keloid; Male; Mid | 1970 |
Keloid.
Topics: Humans; Keloid | 1970 |
[Fibrinolysis in burns and cicatrical keloid of burns].
Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Female; Fibrin Foam; Fibrinolysis; Humans; | 1970 |
The chest keloid.
Topics: Female; Humans; Keloid; Male; Thorax | 1970 |
[Effect of Synalar, Synalar forte, cryotherapy with liquid nitrogen and a variety of other methods in the treatment of keloids].
Topics: Adolescent; Adult; Child; Child, Preschool; Cryosurgery; Fluocinolone Acetonide; Humans; Keloid; Mid | 1970 |
[Keloid and its treatment].
Topics: Humans; Keloid | 1970 |
Irradiation as an etiologic factor in the development of melanoma.
Topics: Adult; Aged; Burns; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Head and Neck Neoplasms; Hum | 1970 |
[Effect of pyrogenal therapy on the morphologic structure of keloid scars].
Topics: Cicatrix; Humans; Keloid; Pyrogens; Skin | 1970 |
[The treatment of keloids and hypertrophic scars by corticosteroids].
Topics: Cicatrix; Female; Humans; Injections, Intradermal; Keloid; Male; Syringes; Triamcinolone Acetonide | 1970 |
[Treatment of keloids with madecassol per os].
Topics: Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Female; Glycosides; Humans; Keloid | 1970 |
[Sphincteral surgery in the immediate postpartum period].
Topics: Adult; Anal Canal; Female; Humans; Infant, Newborn; Keloid; Methods; Postnatal Care; Pregnancy; Rect | 1970 |
[Conservative keloid therapy using Ichtholan special].
Topics: Adolescent; Burns; Child; Child, Preschool; Dermatologic Agents; Humans; Infant; Keloid; Postoperati | 1970 |
Rubinstein-Taybi syndrome. Report of an unusual case.
Topics: Abnormalities, Multiple; Adult; Bone and Bones; Cleft Palate; Elbow; Face; Female; Humans; Intellect | 1971 |
Enzyme activities in hypertrophic scars and keloids.
Topics: Adolescent; Adult; Alanine Transaminase; Alcohol Oxidoreductases; Aspartate Aminotransferases; Black | 1971 |
Tetrahydroxyquinone (THQ) its use in ophthalmology. I.
Topics: Adolescent; Adult; Aged; Child; Cicatrix; Eye Diseases; Female; Humans; Keloid; Macula Lutea; Male; | 1971 |
Complications of ear piercing.
Topics: Culture; Cysts; Dermatitis; Ear Diseases; Ear, External; Esthetics; Ethnicity; Female; Humans; Hyper | 1971 |
Orbital blow-out fracture repair, conjunctival approach.
Topics: Cicatrix; Conjunctiva; Facial Injuries; Fracture Fixation; Humans; Hypertrophy; Keloid; Methods; Orb | 1971 |
[Surgical treatment of the position and shape of the auricles].
Topics: Cartilage; Child; Cicatrix; Ear, External; Humans; Keloid; Male; Methods; Time Factors | 1971 |
Follow-up on treatment of hypertrophic scars and keloids with triamcinolone.
Topics: Adult; Cicatrix; Female; Humans; Hypertrophy; Keloid; Male; Triamcinolone | 1971 |
[Morphogenesis of keloid scars in burns].
Topics: Burns; Cicatrix; Humans; Keloid | 1971 |
[Preliminary results of a treatment of keloids with ionizations with alpha-chymetrypsin].
Topics: Adult; Child, Preschool; Chymotrypsin; Female; Humans; Ions; Keloid; Male | 1967 |
[Dermatological experience with dimethyl sulfoxide (DMSO)].
Topics: Dimethyl Sulfoxide; Dupuytren Contracture; Female; Fibroma; Granuloma; Herpes Zoster; Humans; Keloid | 1967 |
[Local treatment of skin diseases with Volon A tincture].
Topics: Alopecia Areata; Benzalkonium Compounds; Dermatologic Agents; Eczema; Humans; Keloid; Lichen Planus; | 1967 |
[Comparative radioautographic studies on the growth rate of epithelial cells of various carcinomas, precancerous states and normal mucous membrane of the larynx].
Topics: Autoradiography; DNA; Humans; Keloid; Laryngeal Neoplasms; Larynx; Mitosis; Mucous Membrane; Precanc | 1967 |
[Keloids].
Topics: Female; Humans; Keloid | 1967 |
[On physiotherapy of keloids with special reference to radium therapy].
Topics: Adult; Child, Preschool; Female; Humans; Keloid; Middle Aged; Radiotherapy Dosage | 1967 |
[Erythemato-pigmentary reaction with hypertrichosis in the site of injection of hematoporphyrin].
Topics: Adult; Female; Hematoporphyrins; Humans; Hypertrichosis; Injections, Intramuscular; Keloid; Pigmenta | 1967 |
[Interstitial irradiation by iridium 192 in the prevention of recurrence after surgical excision of keloid cicatrices].
Topics: Adult; Cicatrix; Female; Humans; Iridium; Keloid; Methods | 1967 |
[Hormonal induction of the skin through intralesion corticosteroid injections, especially in granuloma anulare, keloid and induratio penis plastica].
Topics: Adrenal Cortex Hormones; Alopecia Areata; Granuloma; Humans; Injections; Keloid; Male; Penile Indura | 1967 |
[Hollowing-out method for the treatment of keloid].
Topics: Adolescent; Adult; Female; Humans; Keloid; Methods; Middle Aged; Surgery, Plastic | 1967 |
Oral treatment of keloid.
Topics: Adult; Burns, Electric; Humans; Keloid; Male; Quinones | 1968 |
Keloid of the cornea.
Topics: Anterior Chamber; Atrophy; Cornea; Descemet Membrane; Edema; Eye Diseases; Female; Humans; Infant; I | 1968 |
[On skin variations in osteopoikilia (Buschke-Ollendorff syndrome)].
Topics: Adult; Blood Protein Electrophoresis; Bone Cysts; Fibroma; Humans; Keloid; Male; Metacarpus; Osteopo | 1968 |
[Comparative clinical and morphological studies of pharyngeal and laryngeal papillomas].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Keloid; Laryngeal Neoplasms; Male; Micro | 1968 |
[Treatment of various skin diseases with topical injections of hydrocortisone].
Topics: Administration, Topical; Anti-Inflammatory Agents; Humans; Hydrocortisone; Injections, Intradermal; | 1968 |
[Pseudosarcomatous xanthofibroma].
Topics: Cytoplasm; Dendrites; Diagnosis, Differential; Female; Fibroma; Histiocytes; Humans; Keloid; Lymphoc | 1968 |
Long-term follow-up of surgically treated thyrotoxic patients.
Topics: Adolescent; Adult; Aged; Cicatrix; Female; Follow-Up Studies; Humans; Hyperthyroidism; Hypoparathyro | 1968 |
Keloids.
Topics: Copper; Humans; Keloid; Pigmentation | 1968 |
[Apropos of the treatment of keloid scars].
Topics: Child; Cicatrix; Humans; Keloid; Male; Skin Neoplasms | 1968 |
[Keloids].
Topics: Humans; Keloid | 1968 |
Keloids.
Topics: Adult; Anesthesia, Local; Female; Humans; Hydrocortisone; Injections, Subcutaneous; Keloid | 1968 |
[The treatment of keloids].
Topics: Adolescent; Adult; Child; Female; Glycerol; Humans; Keloid; Male; Sex Factors; Ultrasonic Therapy; U | 1968 |
Facial disfigurement--an analysis.
Topics: Aging; Cicatrix; Cosmetics; Esthetics; Face; Facial Injuries; Facial Neoplasms; Hemangioma; Humans; | 1968 |
[Therapy of keloids with triamcinolone acetonide].
Topics: Adolescent; Adult; Female; Humans; Injections; Keloid; Male; Middle Aged; Triamcinolone Acetonide | 1968 |
[Late results after plastic reconstruction of the external ear].
Topics: Adolescent; Adult; Child; Ear Deformities, Acquired; Female; Follow-Up Studies; Humans; Keloid; Male | 1968 |
Adolescent thyrotoxicosis.
Topics: Adolescent; Child; Female; Humans; Hyperthyroidism; Hypothyroidism; Keloid; Male; Postoperative Comp | 1968 |
[Record of therapeutic experiences with keloids].
Topics: Adult; Africa; Humans; Keloid; Male | 1968 |
Strengthening of scars with a buried dermal sheet.
Topics: Adolescent; Adult; Carcinoma, Basal Cell; Child; Cicatrix; Dermatologic Surgical Procedures; Dermoid | 1968 |
[Experimental reproduction of Jorge Lobo's blastomycosis].
Topics: Animals; Blastomycosis; Dermatomycoses; Keloid; Mice | 1968 |
[Clinical application of thermometers and thermography in plastic surgery].
Topics: Cicatrix; Humans; Keloid; Skin Ulcer; Surgery, Plastic; Thermography; Thermometers; Vascular Disease | 1968 |
Perifolliculitis capitis abscedens and suffodiens.
Topics: Adult; Anti-Bacterial Agents; Chloramphenicol; Folliculitis; Humans; Keloid; Male; Naphthacenes; Pre | 1969 |
A preferable site for vaccination.
Topics: Adolescent; Adult; Arm; Australia; Female; Humans; Keloid; Methods; Skin Neoplasms; Smallpox; Sunlig | 1969 |
Gastrointestinal, genitourinary, and wound complications.
Topics: Anuria; Drainage; Gastrointestinal Diseases; Hematuria; Humans; Infant; Infant, Newborn; Intestinal | 1969 |
Postoperative keloids--treat or ignore?
Topics: Black or African American; Child; Female; Humans; Keloid; Postoperative Complications; Triamcinolone | 1969 |
[Keloid versus hypertrophic cicatrix].
Topics: Cicatrix; Diagnosis, Differential; Humans; Keloid | 1965 |
Lobo's disease in Surinam patients.
Topics: Adult; Aged; Animals; Blastomycosis; Cricetinae; Female; Fungi; Granuloma; Guinea Pigs; Humans; Kelo | 1965 |
Glaucoma surgery in the Bantu.
Topics: Adolescent; Adult; Aged; Black or African American; Black People; Child; Female; Glaucoma; Humans; K | 1965 |
[A case of keloid of the aural concha].
Topics: Adult; Ear, External; Humans; Keloid; Male | 1965 |
[Jorge Lobo's disease (keloid blastomycosis). Presentation of a new Colombian case].
Topics: Blastomycosis; Colombia; Foot Diseases; Humans; Keloid; Male; Middle Aged | 1965 |
[Selective action of paramethyl-isopropyl-phenol (thymol) on tissues in intense anaplastic-dysplastic proliferative activity].
Topics: Adenocarcinoma; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Division; Condylomata Acuminat | 1965 |
[Treatment of keloids and hypertrophic cicatrices].
Topics: Cicatrix; Humans; Keloid | 1964 |
[Does the method of roentgen irradiation of breast cancer influence the development of keloids in the surgical scar?].
Topics: Breast Neoplasms; Cicatrix; Female; Humans; Keloid; Mastectomy; Radiotherapy Dosage; Wound Healing | 1965 |
[Treatment of keloid].
Topics: Humans; Keloid | 1965 |
The treatment of keloids with triamcinolone acetonide.
Topics: Adolescent; Adult; Black or African American; Female; Humans; Keloid; Male; Middle Aged; Triamcinolo | 1966 |
The treatment of hypertrophic scar, keloid and scar contracture by triamcinolone acetonide.
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix; Cortisone; Female; Humans; Hydrocortisone; Inf | 1966 |
Surgical problems in West Africa.
Topics: Diagnosis; Disease; Humans; Keloid; Medicine, Traditional; Nigeria; Surgical Procedures, Operative; | 1966 |
A case of keloid of the penis.
Topics: Child; Humans; Keloid; Male; Penile Neoplasms | 1966 |
Histologic basis of keloid and hypertrophic scar differentiation. Clinicopathologic correlation.
Topics: Adolescent; Adult; Black or African American; Cicatrix; Classification; Collagen; Ethnology; Female; | 1966 |
[Genealogy of a family with cheloid scars].
Topics: Adult; Child; Cicatrix; Female; Humans; Keloid; Male | 1966 |
[Laryngeal papillomatosis in children and its cryotherapeutic treatment by liquid nitrogen. (Apropos of 9 cases)].
Topics: Adolescent; Child; Child, Preschool; Cold Temperature; Cryosurgery; Female; Humans; Infant; Keloid; | 1966 |
Pachydermoperiostosis. Touraine-Solente-Golé syndrome.
Topics: Adult; Bone Diseases; Diagnosis, Differential; Female; Humans; Keloid; Keratosis; Male; Middle Aged; | 1966 |
[Oligo-N-methyl-morpholine-propylene oxide, a new drug for treatment of keloids and related diseases].
Topics: Adolescent; Adult; Child; Dupuytren Contracture; Humans; Keloid; Male; Morpholines; Penile Induratio | 1966 |
Some observations on keloids in Indians.
Topics: Adolescent; Adult; Aged; Child; Ethnology; Female; Humans; India; Keloid; Male; Middle Aged; White P | 1966 |
Endocrine stimulation of healing. A study of collagen formation and wound tensile strength in pregnant rats.
Topics: Animals; Chorionic Gonadotropin; Collagen; Endocrine Glands; Female; Granulation Tissue; Hemangioma; | 1966 |
[Remote effect in the healing of a keloid by hydrocortisone injections].
Topics: Administration, Topical; Anti-Inflammatory Agents; Back; Child; Ear Deformities, Acquired; Ear, Exte | 1966 |