ketotifen and Cough
ketotifen has been researched along with Cough in 5 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the clinical effect of different combinations of fluticasone propionate (Flu), montelukast sodium (Mon) and ketotifen (Ket) in the treatment of children with cough variant asthma (CVA)." | 9.30 | [Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children]. ( Dai, JH; Tu, JW; Zhu, XH, 2019) |
| "The prophylactic agent ketotifen has been studied in mild-to-moderate asthma." | 9.09 | Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial. ( Kabra, SK; Pandey, RM; Seth, V; Singh, R, 2000) |
| "The efficacy of Ketotifen was examined in the treatment of 113 infants between 6 and 36 months of age presenting with a history of cough and/or wheeze in a multicentre randomized placebo-controlled double-blind study." | 9.07 | A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze. ( Gibbeson, M; Harris, M; Harth, SC; Loh, RK; McKay, KO; Mellis, CM; Rhodes, L; Robertson, IF; Thong, YH; van Asperen, PP, 1992) |
| "23 children with perennial allergic bronchial asthma were treated with ketotifen syrup/capsules." | 7.66 | [Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)]. ( Klein, G; Urbanek, R, 1980) |
| "To study the clinical effect of different combinations of fluticasone propionate (Flu), montelukast sodium (Mon) and ketotifen (Ket) in the treatment of children with cough variant asthma (CVA)." | 5.30 | [Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children]. ( Dai, JH; Tu, JW; Zhu, XH, 2019) |
| "The prophylactic agent ketotifen has been studied in mild-to-moderate asthma." | 5.09 | Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial. ( Kabra, SK; Pandey, RM; Seth, V; Singh, R, 2000) |
| "The efficacy of Ketotifen was examined in the treatment of 113 infants between 6 and 36 months of age presenting with a history of cough and/or wheeze in a multicentre randomized placebo-controlled double-blind study." | 5.07 | A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze. ( Gibbeson, M; Harris, M; Harth, SC; Loh, RK; McKay, KO; Mellis, CM; Rhodes, L; Robertson, IF; Thong, YH; van Asperen, PP, 1992) |
| "23 children with perennial allergic bronchial asthma were treated with ketotifen syrup/capsules." | 3.66 | [Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)]. ( Klein, G; Urbanek, R, 1980) |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Zhu, XH | 1 |
| Tu, JW | 1 |
| Dai, JH | 1 |
| Monie, RD | 1 |
| Smith, AP | 1 |
| Leopold, D | 1 |
| Anderson, G | 1 |
| Davies, BH | 1 |
| Thomas, GO | 1 |
| Urbanek, R | 1 |
| Klein, G | 1 |
| Kabra, SK | 1 |
| Pandey, RM | 1 |
| Singh, R | 1 |
| Seth, V | 1 |
| van Asperen, PP | 1 |
| McKay, KO | 1 |
| Mellis, CM | 1 |
| Loh, RK | 1 |
| Harth, SC | 1 |
| Thong, YH | 1 |
| Harris, M | 1 |
| Robertson, IF | 1 |
| Gibbeson, M | 1 |
| Rhodes, L | 1 |
Trials
4 trials available for ketotifen and Cough
| Article | Year |
|---|---|
[Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children].
Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Cough; Cyclopropanes; Drug Combinati | 2019 |
A double-blind clinical trial of ketotifen and disodium cromoglycate in bronchial asthma.
Topics: Adult; Aged; Asthma; Clinical Trials as Topic; Cough; Cromolyn Sodium; Double-Blind Method; Dyspnea; | 1982 |
Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial.
Topics: Adolescent; Anti-Allergic Agents; Asthma; Child; Child, Preschool; Cough; Dose-Response Relationship | 2000 |
A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze.
Topics: Child, Preschool; Chronic Disease; Cough; Double-Blind Method; Female; Humans; Infant; Ketotifen; Ma | 1992 |
Other Studies
1 other study available for ketotifen and Cough
| Article | Year |
|---|---|
[Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)].
Topics: Administration, Topical; Adolescent; Asthma; Bronchodilator Agents; Child; Child, Preschool; Cough; | 1980 |