Page last updated: 2024-10-30

ketotifen and Cough

ketotifen has been researched along with Cough in 5 studies

Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"To study the clinical effect of different combinations of fluticasone propionate (Flu), montelukast sodium (Mon) and ketotifen (Ket) in the treatment of children with cough variant asthma (CVA)."9.30[Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children]. ( Dai, JH; Tu, JW; Zhu, XH, 2019)
"The prophylactic agent ketotifen has been studied in mild-to-moderate asthma."9.09Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial. ( Kabra, SK; Pandey, RM; Seth, V; Singh, R, 2000)
"The efficacy of Ketotifen was examined in the treatment of 113 infants between 6 and 36 months of age presenting with a history of cough and/or wheeze in a multicentre randomized placebo-controlled double-blind study."9.07A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze. ( Gibbeson, M; Harris, M; Harth, SC; Loh, RK; McKay, KO; Mellis, CM; Rhodes, L; Robertson, IF; Thong, YH; van Asperen, PP, 1992)
"23 children with perennial allergic bronchial asthma were treated with ketotifen syrup/capsules."7.66[Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)]. ( Klein, G; Urbanek, R, 1980)
"To study the clinical effect of different combinations of fluticasone propionate (Flu), montelukast sodium (Mon) and ketotifen (Ket) in the treatment of children with cough variant asthma (CVA)."5.30[Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children]. ( Dai, JH; Tu, JW; Zhu, XH, 2019)
"The prophylactic agent ketotifen has been studied in mild-to-moderate asthma."5.09Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial. ( Kabra, SK; Pandey, RM; Seth, V; Singh, R, 2000)
"The efficacy of Ketotifen was examined in the treatment of 113 infants between 6 and 36 months of age presenting with a history of cough and/or wheeze in a multicentre randomized placebo-controlled double-blind study."5.07A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze. ( Gibbeson, M; Harris, M; Harth, SC; Loh, RK; McKay, KO; Mellis, CM; Rhodes, L; Robertson, IF; Thong, YH; van Asperen, PP, 1992)
"23 children with perennial allergic bronchial asthma were treated with ketotifen syrup/capsules."3.66[Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)]. ( Klein, G; Urbanek, R, 1980)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhu, XH1
Tu, JW1
Dai, JH1
Monie, RD1
Smith, AP1
Leopold, D1
Anderson, G1
Davies, BH1
Thomas, GO1
Urbanek, R1
Klein, G1
Kabra, SK1
Pandey, RM1
Singh, R1
Seth, V1
van Asperen, PP1
McKay, KO1
Mellis, CM1
Loh, RK1
Harth, SC1
Thong, YH1
Harris, M1
Robertson, IF1
Gibbeson, M1
Rhodes, L1

Trials

4 trials available for ketotifen and Cough

ArticleYear
[Clinical effect of fluticasone propionate, montelukast sodium and ketotifen in treatment of cough variant asthma in children].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2019, Volume: 21, Issue:4

    Topics: Acetates; Androstadienes; Anti-Asthmatic Agents; Asthma; Child; Cough; Cyclopropanes; Drug Combinati

2019
A double-blind clinical trial of ketotifen and disodium cromoglycate in bronchial asthma.
    British journal of diseases of the chest, 1982, Volume: 76, Issue:4

    Topics: Adult; Aged; Asthma; Clinical Trials as Topic; Cough; Cromolyn Sodium; Double-Blind Method; Dyspnea;

1982
Ketotifen for asthma in children aged 5 to 15 years: a randomized placebo-controlled trial.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 85, Issue:1

    Topics: Adolescent; Anti-Allergic Agents; Asthma; Child; Child, Preschool; Cough; Dose-Response Relationship

2000
A multicentre randomized placebo-controlled double-blind study on the efficacy of Ketotifen in infants with chronic cough or wheeze.
    Journal of paediatrics and child health, 1992, Volume: 28, Issue:6

    Topics: Child, Preschool; Chronic Disease; Cough; Double-Blind Method; Female; Humans; Infant; Ketotifen; Ma

1992

Other Studies

1 other study available for ketotifen and Cough

ArticleYear
[Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)].
    Klinische Padiatrie, 1980, Volume: 192, Issue:4

    Topics: Administration, Topical; Adolescent; Asthma; Bronchodilator Agents; Child; Child, Preschool; Cough;

1980