Page last updated: 2024-10-29

ketorolac and Icterus

ketorolac has been researched along with Icterus in 1 studies

Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.

Research Excerpts

ExcerptRelevanceReference
" We present the first patient, to our knowledge, who reacted to the use of the analgesic ketorolac with progressive reduction in biliary output, in the setting of malignant biliary obstruction from duodenal adenocarcinoma."4.31A possible role for ketorolac in the management of increased biliary drain output. ( Cohen, NA; Golas, BJ; Gross, A; Khajoueinejad, N; Yu, AT, 2023)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Yu, AT1
Khajoueinejad, N1
Gross, A1
Golas, BJ1
Cohen, NA1

Other Studies

1 other study available for ketorolac and Icterus

ArticleYear
A possible role for ketorolac in the management of increased biliary drain output.
    Clinics and research in hepatology and gastroenterology, 2023, Volume: 47, Issue:6

    Topics: Adenocarcinoma; Cholestasis; Drainage; Humans; Jaundice; Ketorolac; Treatment Outcome

2023