Page last updated: 2024-10-29

ketamine and Sialorrhea

ketamine has been researched along with Sialorrhea in 7 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Sialorrhea: Increased salivary flow.

Research Excerpts

ExcerptRelevanceReference
"To compare atropine with placebo as an adjunct to ketamine sedation in children undergoing minor painful procedures."5.12Is atropine needed with ketamine sedation? A prospective, randomised, double blind study. ( Geelhoed, GC; Heinz, P; Pascoe, EM; Wee, C, 2006)
"Midazolam and ketamine were administered consecutively by intravenous route under cardiorespiratory monitoring for painful procedures of pediatric hematology."3.81The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology. ( Çakmak, E; Demirsoy, U; Gelen, SA; Sarper, N; Zengin, E, 2015)
"Ketamine is a relatively safe drug for use in children with few intervention-based side effects."1.39Is prophylactic atropine necessary during ketamine sedation in children? ( Ang, AS; Chew, SP; Chong, JH, 2013)
"Interventions for hypersalivation (most commonly suctioning) occurred in 4."1.35Adjunctive atropine is unnecessary during ketamine sedation in children. ( Barcega, B; Brown, L; Christian-Kopp, S; Denmark, TK; Green, SM; Khan, A; Kim, GJ; Moynihan, JA; Sherwin, TS; Stewart, G, 2008)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chong, JH1
Chew, SP1
Ang, AS1
Gelen, SA1
Sarper, N1
Demirsoy, U1
Zengin, E1
Çakmak, E1
Shah, UK1
Nicholas, B1
Hurd, J1
Nesargi, S1
Corao-Uribe, D1
Kye, YC1
Rhee, JE1
Kim, K1
Kim, T1
Jo, YH1
Jeong, JH1
Lee, JH1
Heinz, P1
Geelhoed, GC1
Wee, C1
Pascoe, EM1
Casagrande, AM1
Brown, L1
Christian-Kopp, S1
Sherwin, TS1
Khan, A1
Barcega, B1
Denmark, TK1
Moynihan, JA1
Kim, GJ1
Stewart, G1
Green, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is Atropine Needed With Ketamine Sedation?[NCT00834470]Phase 4140 participants (Actual)Interventional2008-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for ketamine and Sialorrhea

ArticleYear
Clinical effects of adjunctive atropine during ketamine sedation in pediatric emergency patients.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:9

    Topics: Adjuvants, Anesthesia; Anesthetics, Dissociative; Atropine; Child, Preschool; Conscious Sedation; Do

2012
Is atropine needed with ketamine sedation? A prospective, randomised, double blind study.
    Emergency medicine journal : EMJ, 2006, Volume: 23, Issue:3

    Topics: Adjuvants, Anesthesia; Adolescent; Anesthetics, Dissociative; Atropine; Child; Child, Preschool; Dou

2006

Other Studies

5 other studies available for ketamine and Sialorrhea

ArticleYear
Is prophylactic atropine necessary during ketamine sedation in children?
    Journal of paediatrics and child health, 2013, Volume: 49, Issue:4

    Topics: Adjuvants, Anesthesia; Adolescent; Anesthetics, Dissociative; Atropine; Child; Child, Preschool; Eme

2013
The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:4

    Topics: Adolescent; Analgesia; Analgesics; Bone Marrow Examination; Child; Child, Preschool; Deep Sedation;

2015
Case report: Langerhans cell histiocytosis presenting as massive cervical adenopathy and retropharyngeal thickening: importance of chest radiography and coordinated airway and anesthetic management.
    Pediatric emergency care, 2010, Volume: 26, Issue:2

    Topics: Airway Obstruction; Anesthesia, Intravenous; Anesthetics, Dissociative; Combined Modality Therapy; D

2010
Propofol for office oral and maxillofacial anesthesia: the case against low-dose ketamine.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2006, Volume: 64, Issue:4

    Topics: Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetics, Dissoci

2006
Adjunctive atropine is unnecessary during ketamine sedation in children.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2008, Volume: 15, Issue:4

    Topics: Adjuvants, Anesthesia; Adolescent; Anesthetics, Dissociative; Atropine; Child; Child, Preschool; Eme

2008