Page last updated: 2024-10-29
ketamine and Hypoxia
ketamine has been researched along with Hypoxia in 77 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare ketamine-butorphanol-azaperone-medetomidine (KBAM) to detomidine-etorphine-acepromazine (DEA) for field anesthesia in captive Przewalski horses (Equus przewalskii)." | 9.51 | A randomized clinical trial to compare ketamine-butorphanol-azaperone-medetomidine and detomidine-etorphine-acepromazine for anesthesia of captive Przewalski horses (Equus przewalskii). ( Anderson, NE; Delnatte, P; Dutton, C; Ferro, A; Larouche, CB; Milnes, EL; Skelding, AM, 2022) |
| "The protective effects of ketamine against hypoxia-induced injury was assessed using cell viability and adhesion assays, quantitative polymerase chain reaction, and western blotting." | 7.96 | Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells. ( Hu, Y; Liu, J; Meng, Z; Su, Y; Yang, S; Zhou, X, 2020) |
| "We performed the current study to test the hypothesis that ketamine pretreatment will reduce fetal ACTH responses to hypoxic hypoxia (HH)." | 7.81 | Ketamine Attenuates the ACTH Response to Hypoxia in Late-Gestation Ovine Fetus. ( Chang, EI; Wood, CE, 2015) |
| "Hypopneic hypoventilation as detected by capnography is common in children undergoing sedation with ketamine with or without midazolam." | 7.77 | Detection of hypoventilation by capnography and its association with hypoxia in children undergoing sedation with ketamine. ( Chen, L; Langhan, ML; Marshall, C; Santucci, KA, 2011) |
| "Using altitude hypoxia model, in situ hybridization and NADPH-d histochemistry, we investigated the effects of ketamine and L-NAME (blocker of NOS) on NOS and somatostatin mRNA (SS mRNA) expression in the rat hypothalamus following acute altitude hypoxia." | 7.70 | [Ketamine and L-NAME inhibit NOS and somatostatin mRNA expression induced by altitude hypoxia in the rat hypothalamus]. ( Fan, XT; Ruan, HZ, 2000) |
| "The purpose of this study is to investigate the hypothesis that ketamine, a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor, attenuates hypoxia-induced striatal dopamine release in vivo." | 7.69 | Ketamine antagonizes hypoxia-induced dopamine release in rat striatum. ( Chiou, AL; Lin, JC; Wang, Y; Yang, ST, 1995) |
| "To study the effects of ketamine on structurally remodeled pulmonary arteries from rats with hypoxic pulmonary hypertension (PH) and the effects of ketamine on endothelium-dependent and -independent relaxation, rats were exposed to hypobaric hypoxia (air at 380 mm Hg for 10 days)." | 7.69 | Vasodilatory effects of ketamine on pulmonary arteries in rats with chronic hypoxic pulmonary hypertension. ( Maruyama, J; Maruyama, K; Miyasaka, K; Muneyuki, M; Yokochi, A, 1995) |
| "The present study was designed to determine whether ketamine could maintain hepatic circulation and oxygen metabolism even in the presence of serious hepatic hypoxia." | 7.68 | [Effect of ketamine on hepatic circulation and oxygen metabolism during hypoxia in dog]. ( Oohara, K, 1993) |
| " In group DSI, patients received a dissociative dose of ketamine followed by 3 minutes of preoxygenation and paralysis using IV succinylcholine for intubation." | 5.69 | Peri-Intubation Hypoxia After Delayed Versus Rapid Sequence Intubation in Critically Injured Patients on Arrival to Trauma Triage: A Randomized Controlled Trial. ( Bandyopadhyay, A; Jafra, A; Jain, K; Kumar, P; Thakur, H; Yaddanapudi, LN, 2023) |
| "Ketamine is a well-studied and safe medication used for procedural sedation in the pediatric emergency department (ED)." | 5.56 | Ketamine Sedation and Hypoxia: A Quality Improvement Project to Reduce Respiratory Events Receiving Intervention. ( Bernier, B; DiStefano, M; Faulk, D; Leonard, J; Wathen, J; Wiersma, AJ, 2020) |
| "To compare ketamine-butorphanol-azaperone-medetomidine (KBAM) to detomidine-etorphine-acepromazine (DEA) for field anesthesia in captive Przewalski horses (Equus przewalskii)." | 5.51 | A randomized clinical trial to compare ketamine-butorphanol-azaperone-medetomidine and detomidine-etorphine-acepromazine for anesthesia of captive Przewalski horses (Equus przewalskii). ( Anderson, NE; Delnatte, P; Dutton, C; Ferro, A; Larouche, CB; Milnes, EL; Skelding, AM, 2022) |
| "Ketamine was administered during 149 procedures." | 5.36 | Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine. ( Bair, E; Bratton, SL; Feinstein, JA; Hammer, GB; Kamra, K; Kuan, CC; Maan, H; Ramamoorthy, C; Williams, GD, 2010) |
| "0044), history of sleep apnea (P = 0." | 5.19 | Capnographic monitoring of propofol-based sedation during colonoscopy. ( Albert, J; Bojunga, J; Filmann, N; Friedrich-Rust, M; Herrmann, E; Kannengiesser, M; Meckbach, Y; Schroeter, H; Trojan, J; Welte, C; Welte, M; Zeuzem, S, 2014) |
| " Here, we focused on the basic physiological effects of ketamine as a recreational drug and its possible interactions with fentanyl-a highly potent opioid that induces strong respiratory depression and robust brain hypoxia." | 4.31 | Basic metabolic and vascular effects of ketamine and its interaction with fentanyl. ( Choi, S; Curay, CM; Irwin, MR; Kiyatkin, EA, 2023) |
| "The protective effects of ketamine against hypoxia-induced injury was assessed using cell viability and adhesion assays, quantitative polymerase chain reaction, and western blotting." | 3.96 | Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells. ( Hu, Y; Liu, J; Meng, Z; Su, Y; Yang, S; Zhou, X, 2020) |
| " We have previously reported that ketamine, a noncompetitive N-methyl-D-aspartate receptor antagonist, can modify the fetal hemodynamic and ACTH responses to ventilatory hypoxia and cerebral ischemia-reperfusion." | 3.83 | Ketamine modulates fetal hemodynamic and endocrine responses to umbilical cord occlusion. ( Antolic, A; Chang, EI; Wood, CE; Zarate, MA, 2016) |
| "We performed the current study to test the hypothesis that ketamine pretreatment will reduce fetal ACTH responses to hypoxic hypoxia (HH)." | 3.81 | Ketamine Attenuates the ACTH Response to Hypoxia in Late-Gestation Ovine Fetus. ( Chang, EI; Wood, CE, 2015) |
| "Hypopneic hypoventilation as detected by capnography is common in children undergoing sedation with ketamine with or without midazolam." | 3.77 | Detection of hypoventilation by capnography and its association with hypoxia in children undergoing sedation with ketamine. ( Chen, L; Langhan, ML; Marshall, C; Santucci, KA, 2011) |
| " Anesthesia was provided with an infusion of midazolam, fentanyl, S-ketamine and low concentrations of isoflurane in oxygen." | 3.74 | Balanced anesthesia and ventilation strategies for an alpaca (Lama pacos) with an increased anesthetic-risk. ( Jäggin-Schmucker, N; Larenza, MP; Zanolari, P, 2008) |
| " Pressure-flow plots were measured during normoxia and hypoxia (systemic arterial PO2 reduced to about 60 and about 50 mm Hg) on separate days in the conscious state, during ketamine anesthesia, and during propofol anesthesia." | 3.70 | Ketamine preserves and propofol potentiates hypoxic pulmonary vasoconstriction compared with the conscious state in chronically instrumented dogs. ( Murray, PA; Nakayama, M, 1999) |
| "Using altitude hypoxia model, in situ hybridization and NADPH-d histochemistry, we investigated the effects of ketamine and L-NAME (blocker of NOS) on NOS and somatostatin mRNA (SS mRNA) expression in the rat hypothalamus following acute altitude hypoxia." | 3.70 | [Ketamine and L-NAME inhibit NOS and somatostatin mRNA expression induced by altitude hypoxia in the rat hypothalamus]. ( Fan, XT; Ruan, HZ, 2000) |
| "The purpose of this study is to investigate the hypothesis that ketamine, a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor, attenuates hypoxia-induced striatal dopamine release in vivo." | 3.69 | Ketamine antagonizes hypoxia-induced dopamine release in rat striatum. ( Chiou, AL; Lin, JC; Wang, Y; Yang, ST, 1995) |
| "The purpose of this study was to determine the cumulative effects of brief intervals of hypoxia and hypercapnia on the pulsatile characteristics of the pulmonary arterial circulation of 48-h-old compared with 2-wk-old open-chest Yorkshire pigs while using two different anesthetic regimens: 1) azaperone and ketamine (4 and 12 mg/kg im, respectively) and 2) thiopental sodium (25 mg/kg i." | 3.69 | Pulmonary hydraulic impedance responses to hypoxia and hypercapnia in newborn pigs. ( Analouei, AR; Cockerham, JT; Crescenzo, DG; Domkowski, PW; Dyer, KL; Hopkins, RA; Kot, PA; Messier, RH; Wallace, RB; Wang, Y, 1994) |
| "To study the effects of ketamine on structurally remodeled pulmonary arteries from rats with hypoxic pulmonary hypertension (PH) and the effects of ketamine on endothelium-dependent and -independent relaxation, rats were exposed to hypobaric hypoxia (air at 380 mm Hg for 10 days)." | 3.69 | Vasodilatory effects of ketamine on pulmonary arteries in rats with chronic hypoxic pulmonary hypertension. ( Maruyama, J; Maruyama, K; Miyasaka, K; Muneyuki, M; Yokochi, A, 1995) |
| "The present study was designed to determine whether ketamine could maintain hepatic circulation and oxygen metabolism even in the presence of serious hepatic hypoxia." | 3.68 | [Effect of ketamine on hepatic circulation and oxygen metabolism during hypoxia in dog]. ( Oohara, K, 1993) |
| " Selected compounds were then tested for their ability to produce ketamine appropriate responding in monkeys and/or to show neuroprotective effects in a baby rat hypoxia/ischemia model." | 3.68 | Synthesis, phencyclidine-like pharmacology, and antiischemic potential of meta-substituted 1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridines. ( de Costa, B; France, CP; Jacobson, AE; Mattson, MV; Olney, JW; Price, MT; Rice, KC; Thurkauf, A; Woods, JH, 1990) |
| "Ketamine is often used in combination with tranquilizers to produce surgical anesthesia in rabbits." | 3.68 | Ketamine/xylazine/butorphanol: a new anesthetic combination for rabbits. ( Avison, DL; Corning, BF; Lipman, NS; Marini, RP, 1992) |
| " In cell cultures, CgTx inhibited hypoxia-induced 45Ca accumulation and neuronal injury minimally, compared to the NMDA antagonist ketamine." | 3.68 | Treatment with conotoxin, an 'N-type' calcium channel blocker, in neuronal hypoxic-ischemic injury. ( Clark, WM; Madden, KP; Marcoux, FW; Probert, AW; Rivier, J; Weber, ML; Zivin, JA, 1990) |
| "The ventilatory responses to isocapnic hypoxia and hypercapnia were studied in seven chronically tracheostomized dogs awake and during anesthesia with pentobarbital (30 mg/kg, iv), ketamine, or thiopental (10 and 15 mg/kg, respectively, followed by infusion)." | 3.65 | Hypoxic ventilatory drive in dogs during thiopental, ketamine, or pentobarbital anesthesia. ( Cohen, PJ; Hirshman, CA; McCullough, RE; Weil, JV, 1975) |
| "ketamine dosages were evaluated: 0." | 2.72 | Effects of ketamine on carfentanil and xylazine immobilization of white-tailed deer (Odocoileus virginianus). ( Miller, KV; Osborn, DA; Ramsay, EC; Schumacher, J; Storms, TN, 2006) |
| "Hypoxemia was rare except in the propofol group (15." | 2.68 | Total intravenous anesthesia for children undergoing brief diagnostic or therapeutic procedures. ( Barst, SM; McDowall, RH; Scher, CS, 1995) |
| "Ketamine is a well-studied and safe medication used for procedural sedation in the pediatric emergency department (ED)." | 1.56 | Ketamine Sedation and Hypoxia: A Quality Improvement Project to Reduce Respiratory Events Receiving Intervention. ( Bernier, B; DiStefano, M; Faulk, D; Leonard, J; Wathen, J; Wiersma, AJ, 2020) |
| "Mild hypoxemia occurred in 24% of cases and resolved with nasal cannula." | 1.43 | Deep Sedation for Pediatric Dental Procedures: Is this a Safe and Effective Option? ( Ahmed, SS; Hicks, SR; Nitu, ME; Slaven, JE, 2016) |
| "Use of ketamine in patients requiring extracorporeal membrane oxygenation (ECMO) has rarely been reported, and the optimal dosing strategy remains unclear." | 1.43 | High-Dose Sedation and Analgesia During Extracorporeal Membrane Oxygenation: A Focus on the Adjunctive Use of Ketamine. ( Cochran, JB; Floroff, CK; Hassig, TB; Mazur, JE, 2016) |
| "Atrial septal defects and ventricular septal defects are often encountered in patients presenting for treatment under anesthesia." | 1.42 | ASD and VSD Flow Dynamics and Anesthetic Management. ( Yen, P, 2015) |
| "For treatment of hypoxemia, delivery of the minimum effective oxygen flow rate is advantageous during field anesthesia because it prolongs the life of the oxygen cylinder." | 1.40 | Low flow oxygen therapy from a portable oxygen concentrator or an oxygen cylinder effectively treats hypoxemia in anesthetized white-tailed deer (Odocoileus virginianus). ( Caulkett, N; Duke-Novakovski, T; Fahlman, A; Woodbury, M; Wourms, V, 2014) |
| "The purpose of this study was to examine the effects of a clinically relevant opioid on the production of augmented breaths (ABs) in unanesthetized animals breathing normal room air, using a dosage which does not depress breathing." | 1.37 | The "other" respiratory effect of opioids: suppression of spontaneous augmented ("sigh") breaths. ( Azubike, E; Bell, HJ; Haouzi, P, 2011) |
| "Ketamine is a sympathetic nervous system-activating anaesthetic that preserves cardiovascular stability." | 1.36 | Effects of ketamine on hypoxic pulmonary vasoconstriction in the isolated perfused lungs of endotoxaemic mice. ( Busch, CJ; Gebhard, MM; Martin, EO; Motsch, J; Spöhr, FA; Weimann, J, 2010) |
| "Ketamine was administered during 149 procedures." | 1.36 | Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine. ( Bair, E; Bratton, SL; Feinstein, JA; Hammer, GB; Kamra, K; Kuan, CC; Maan, H; Ramamoorthy, C; Williams, GD, 2010) |
| "Twenty (69%) of the 29 patients with laryngospasm received IM ketamine (OR, 5." | 1.35 | Serious adverse events during procedural sedation with ketamine. ( Bachur, R; Melendez, E, 2009) |
| " Seventy-seven adverse events occurred in 68 (6." | 1.32 | Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department. ( Agrawal, D; Gupta, R; Krauss, B; Manzi, SF, 2003) |
| " Because concern about delayed adverse effects commonly delays discharge after sedation, we attempted to establish the timing of adverse effects in our cohort of procedural sedations." | 1.32 | When is a patient safe for discharge after procedural sedation? The timing of adverse effect events in 1367 pediatric procedural sedations. ( Azer, MM; Newman, DH; Pitetti, RD; Singh, S, 2003) |
| "Adverse effects included transient laryngospasm (n = 9), transient partial airway obstruction (n = 5), apnea with bradycardia (n = 1), emesis during the procedure (n = 2), emesis during recovery (n = 9), mild recovery agitation (n = 10), moderate-to-severe recovery agitation (n = 1), and excessive salivation (n = 4)." | 1.31 | Ketamine sedation for pediatric critical care procedures. ( Abd Allah, S; Cline, J; Denmark, TK; Green, SM; Roghair, C; Rothrock, SG, 2001) |
| "Acute fetal hypoxemia was induced repeatedly by reducing uterine blood flow." | 1.29 | Effect of drugs on chemoreceptor responsiveness in fetal sheep. ( Baan, J; Boekkooi, PF; Rudolph, AM; Teitel, DF, 1995) |
| "Increasing perfusate [Ca2+] during anoxia from zero to 4 mM resulted in progressively less recovery." | 1.28 | The pathophysiology of anoxic injury in central nervous system white matter. ( Ransom, BR; Stys, PK; Waxman, SG, 1990) |
| "Ketamine was chosen as the intravenous agent for its positive inotropic and chronotropic action." | 1.26 | Continuous ketamine infusion for one-lung anaesthesia. ( Lumb, PD; Silvay, G; Weinreich, AI, 1980) |
| "In the awake state, arterial hypoxemia is counteracted by a mechanism which tends to normalize the ventilation/perfusion ratio of the lungs by way of a hypoxia-induced vasoconstriction in poorly ventilated areas." | 1.26 | Hypoxia-induced vasoconstriction in isolated perfused lungs exposed to injectable or inhalation anesthetics. ( Bjertnaes, LJ, 1977) |
Research
Studies (77)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (15.58) | 18.7374 |
| 1990's | 20 (25.97) | 18.2507 |
| 2000's | 18 (23.38) | 29.6817 |
| 2010's | 19 (24.68) | 24.3611 |
| 2020's | 8 (10.39) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Maraschin, JC | 1 |
| Frias, AT | 1 |
| Hernandes, PM | 1 |
| Batistela, MF | 1 |
| Martinez, LM | 1 |
| Joca, SRL | 1 |
| Graeff, FG | 1 |
| Audi, EA | 1 |
| Spera de Andrade, TGC | 1 |
| Zangrossi, H | 1 |
| Milnes, EL | 1 |
| Skelding, AM | 1 |
| Larouche, CB | 1 |
| Ferro, A | 1 |
| Delnatte, P | 1 |
| Dutton, C | 1 |
| Anderson, NE | 1 |
| David, EM | 1 |
| Pacharinsak, C | 1 |
| Jampachaisri, K | 1 |
| Hagan, L | 1 |
| Marx, JO | 1 |
| Irwin, MR | 1 |
| Curay, CM | 1 |
| Choi, S | 1 |
| Kiyatkin, EA | 1 |
| Bandyopadhyay, A | 1 |
| Kumar, P | 1 |
| Jafra, A | 1 |
| Thakur, H | 1 |
| Yaddanapudi, LN | 1 |
| Jain, K | 1 |
| Cardoso, CG | 1 |
| Ayer, IM | 1 |
| Jorge, AT | 1 |
| Honsho, CS | 1 |
| Mattos-Junior, E | 1 |
| Wiersma, AJ | 1 |
| Bernier, B | 1 |
| Leonard, J | 1 |
| Faulk, D | 1 |
| DiStefano, M | 1 |
| Wathen, J | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 2 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 3 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 5 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 3 |
| Zhang, C | 3 |
| Chen, L | 3 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 2 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 9 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
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Clinical Trials (6)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Ketamine Versus Sufentanil on Cerebral Glutamate After Traumatic Brain Injury : a Randomized, Double-blinded, Microdialysis Study[NCT02232347] | Phase 2 | 20 participants (Anticipated) | Interventional | 2014-10-31 | Not yet recruiting | ||
| Changes of the Short Portable Mental Status Questionnaire (SPMSQ-E) After Ketamine Administration on Ophthalmic Surgery in Geriatric Population.[NCT02049411] | Phase 2 | 80 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| Do Patients Need Pre-Procedural Fasting for Coronary Artery Procedures?[NCT02562638] | 240 participants (Anticipated) | Interventional | 2015-10-31 | Not yet recruiting | |||
| Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915] | 314 participants (Actual) | Observational | 2017-08-01 | Completed | |||
| Effect Of Ketamine Infusion On Oxygenation And Ventilation Mechanics In Patients With Chronic Obstructive Pulmonary Disease Applied One Lung Ventilation[NCT02962999] | Phase 4 | 30 participants (Actual) | Interventional | 2017-01-31 | Completed | ||
| The Effect of Different Anesthesia Techniques on Cerebral Oxygenation in Thoracic Surgery[NCT04760262] | 30 participants (Actual) | Observational | 2017-03-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
4 reviews available for ketamine and Hypoxia
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Neuroprotection by ketamine: a review of the experimental and clinical evidence.
Topics: Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation; Excitatory Amino Acid Antagonis | 2010 |
Neuroprotection by ketamine: a review of the experimental and clinical evidence.
Topics: Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation; Excitatory Amino Acid Antagonis | 2010 |
Neuroprotection by ketamine: a review of the experimental and clinical evidence.
Topics: Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation; Excitatory Amino Acid Antagonis | 2010 |
Neuroprotection by ketamine: a review of the experimental and clinical evidence.
Topics: Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation; Excitatory Amino Acid Antagonis | 2010 |
[Basis and new aspects of the effect of anaesthetics on cerebral function].
Topics: Anesthetics; Barbiturates; Brain; Brain Edema; Brain Neoplasms; Cerebrovascular Circulation; Chlorof | 1973 |
Postoperative care.
Topics: Ambulatory Care; Anaphylaxis; Anesthesia; Anesthesia, Conduction; Eye Diseases; Heart Diseases; Hear | 1973 |
Trials
11 trials available for ketamine and Hypoxia
| Article | Year |
|---|---|
A randomized clinical trial to compare ketamine-butorphanol-azaperone-medetomidine and detomidine-etorphine-acepromazine for anesthesia of captive Przewalski horses (Equus przewalskii).
Topics: Acepromazine; Anesthesia; Animals; Azaperone; Butorphanol; Etorphine; Heart Rate; Horses; Hypnotics | 2022 |
Peri-Intubation Hypoxia After Delayed Versus Rapid Sequence Intubation in Critically Injured Patients on Arrival to Trauma Triage: A Randomized Controlled Trial.
Topics: Humans; Hypoxia; Intubation, Intratracheal; Ketamine; Paralysis; Rapid Sequence Induction and Intuba | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Compared to etorphine-azaperone, the ketamine-butorphanol-medetomidine combination is also effective at immobilizing zebra (Equus zebra).
Topics: Analgesics, Opioid; Anesthetics, Dissociative; Animals; Animals, Wild; Azaperone; Blood Pressure; Bu | 2019 |
Capnographic monitoring of propofol-based sedation during colonoscopy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Apnea; Body Mass Index; Capnography; Colono | 2014 |
[The tissue oxygen cascade as the marker in different schemes of general anesthesia on dynamics of the hypoxic syndrome in patients, suffering an acute hemorrhage of high operative risk].
Topics: Acute Disease; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; Female; Fen | 2008 |
The Lancaster experience of 2.0 to 2.5 mg/kg intramuscular ketamine for paediatric sedation: 501 cases and analysis.
Topics: Child; Child, Preschool; Conscious Sedation; Dose-Response Relationship, Drug; Emergency Service, Ho | 2004 |
Effects of ketamine on carfentanil and xylazine immobilization of white-tailed deer (Odocoileus virginianus).
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Animals, Wild; Bl | 2006 |
Total intravenous anesthesia for children undergoing brief diagnostic or therapeutic procedures.
Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Child; Child, Preschool; Etomid | 1995 |
Safety and effectiveness of intranasal administration of sedative medications (ketamine, midazolam, or sufentanil) for urgent brief pediatric dental procedures.
Topics: Administration, Intranasal; Anesthesia Recovery Period; Anesthesia, Dental; Child Behavior; Child, P | 1993 |
Hemodynamic effects of ketamine, hypoxia and hyperoxia in children with surgically treated congenital heart disease residing greater than or equal to 1,200 meters above sea level.
Topics: Altitude; Child, Preschool; Female; Heart Defects, Congenital; Humans; Hypoxia; Ketamine; Male; Oxyg | 1991 |
Other Studies
63 other studies available for ketamine and Hypoxia
| Article | Year |
|---|---|
Antipanic-like effect of esketamine and buprenorphine in rats exposed to acute hypoxia.
Topics: Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antidepressive Agents; Buprenorphine; Depressive D | 2022 |
Use of Ketamine or Xylazine to Provide Balanced Anesthesia with Isoflurane in C57BL/6J Mice.
Topics: Anesthetics, Inhalation; Animals; Balanced Anesthesia; Crystalloid Solutions; Female; Hypovolemia; H | 2022 |
Basic metabolic and vascular effects of ketamine and its interaction with fentanyl.
Topics: Analgesics, Opioid; Animals; Fentanyl; Humans; Hypoxia; Hypoxia, Brain; Ketamine; Oxygen; Rats | 2023 |
A comparative study of the cardiopulmonary and sedative effects of a single intramuscular dose of ketamine anesthetic combinations in rabbits.
Topics: Acepromazine; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Arterial Pressure; Cross | 2020 |
Ketamine Sedation and Hypoxia: A Quality Improvement Project to Reduce Respiratory Events Receiving Intervention.
Topics: Child; Conscious Sedation; Emergency Service, Hospital; Humans; Hypoxia; Ketamine; Prospective Studi | 2020 |
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Topics: Apoptosis; Cell Survival; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia; Ketamine; Oxidati | 2020 |
Procedural sedation by advanced care paramedics for emergency gastrointestinal endoscopy.
Topics: Allied Health Personnel; Analgesics; Arrhythmias, Cardiac; Datasets as Topic; Emergency Service, Hos | 2019 |
Arterial pH and blood gas values in rats under three types of general anesthesia: a chronobiological study.
Topics: Anesthesia, General; Anesthetics, General; Animals; Blood Gas Analysis; Chronobiology Phenomena; Dru | 2018 |
Low flow oxygen therapy from a portable oxygen concentrator or an oxygen cylinder effectively treats hypoxemia in anesthetized white-tailed deer (Odocoileus virginianus).
Topics: Anesthesia, General; Anesthetics, Dissociative; Animals; Deer; Female; Hypnotics and Sedatives; Hypo | 2014 |
Ketamine Attenuates the ACTH Response to Hypoxia in Late-Gestation Ovine Fetus.
Topics: Adrenocorticotropic Hormone; Anesthetics, Dissociative; Animals; Blood Pressure; Female; Fetus; Gest | 2015 |
ASD and VSD Flow Dynamics and Anesthetic Management.
Topics: Anesthesia, Dental; Anesthetics, Dissociative; Anesthetics, General; Cardiac Output; Conscious Sedat | 2015 |
Delayed sequence intubation with ketamine in 2 critically ill children.
Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Atropine; Child; Critical Illness; Dopamine; Dopami | 2016 |
High-Dose Sedation and Analgesia During Extracorporeal Membrane Oxygenation: A Focus on the Adjunctive Use of Ketamine.
Topics: Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Extracorporeal Membrane Oxygenatio | 2016 |
Deep Sedation for Pediatric Dental Procedures: Is this a Safe and Effective Option?
Topics: Adjuvants, Anesthesia; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetics, Intravenous; Cat | 2016 |
Ketamine modulates fetal hemodynamic and endocrine responses to umbilical cord occlusion.
Topics: Adrenocorticotropic Hormone; Analgesics; Animals; Blood Pressure; Carbon Dioxide; Female; Fetal Bloo | 2016 |
Serious adverse events during procedural sedation with ketamine.
Topics: Boston; Case-Control Studies; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospital; F | 2009 |
Effects of ketamine on hypoxic pulmonary vasoconstriction in the isolated perfused lungs of endotoxaemic mice.
Topics: Anesthetics, Dissociative; Animals; Blood Pressure; Disease Models, Animal; Endotoxemia; Hypoxia; Ke | 2010 |
Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine.
Topics: Adolescent; Anesthesia, General; Anesthetics, Dissociative; Blood Pressure; Cardiac Surgical Procedu | 2010 |
[The protection of selenium-tea in Enshi on the damage of hypoxia/reoxygenation in mice and the influence of ketamine on it].
Topics: Animals; Female; Hypoxia; Ketamine; Male; Mice; Mice, Inbred Strains; Selenium; Tea | 2003 |
Detection of hypoventilation by capnography and its association with hypoxia in children undergoing sedation with ketamine.
Topics: Adolescent; Anesthetics, Dissociative; Capnography; Carbon Dioxide; Child; Child, Preschool; Conscio | 2011 |
Medetomidine/midazolam/ketamine anaesthesia in ferrets: effects on cardiorespiratory parameters and evaluation of plasma drug concentrations.
Topics: Anesthesia; Anesthetics, Combined; Animals; Blood Gas Analysis; Blood Pressure; Dose-Response Relati | 2011 |
Anesthesia case of the month. Hypoxemia during anesthesia.
Topics: Acidosis; Anesthesia, General; Anesthetics, Dissociative; Animals; Dog Diseases; Dogs; Female; Hypox | 2011 |
The "other" respiratory effect of opioids: suppression of spontaneous augmented ("sigh") breaths.
Topics: Analgesics, Opioid; Animals; Hypnotics and Sedatives; Hypoxia; Ketamine; Male; Morphine; Naloxone; R | 2011 |
Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department.
Topics: Adjuvants, Anesthesia; Analgesia; Anesthetics, Combined; Child; Child, Preschool; Chloral Hydrate; C | 2003 |
When is a patient safe for discharge after procedural sedation? The timing of adverse effect events in 1367 pediatric procedural sedations.
Topics: Adjuvants, Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissociative; | 2003 |
Neurological deficit and disturbances in higher nervous activity during modeling of perinatal hypoxic-ischemic damage to the central nervous system in rat pups.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Central Nervous System; Central Nervous System Diseas | 2003 |
Effects of an alveolar recruitment maneuver on cardiovascular and respiratory parameters during total intravenous anesthesia in ponies.
Topics: Anesthesia, Intravenous; Animals; Benzodiazepines; Catheterization, Peripheral; Horse Diseases; Hors | 2006 |
Low-dose ketamine: efficacy in pediatric sedation.
Topics: Adolescent; Atropine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Evaluation; Dr | 2007 |
The combative multitrauma patient: a protocol for prehospital management.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Behavior Control; Clinical Protocols; Drug Therapy, Co | 2007 |
Balanced anesthesia and ventilation strategies for an alpaca (Lama pacos) with an increased anesthetic-risk.
Topics: Anesthesia; Anesthetics; Animals; Camelids, New World; Female; Fentanyl; Hypnotics and Sedatives; Hy | 2008 |
[The use of mepixantone in general anesthesia].
Topics: Anesthesia, General; Central Nervous System Stimulants; Humans; Hypoxia; Ketamine; Postoperative Com | 1983 |
Phenytoin improves hemodynamic tolerance and survival after severe hypoxia.
Topics: Anesthesia, General; Animals; Blood Pressure; Heart Rate; Hemodynamics; Hypoxia; Ketamine; Phenytoin | 1984 |
Continuous ketamine infusion for one-lung anaesthesia.
Topics: Adult; Aged; Anesthesia, Intravenous; Blood Pressure; Cardiac Output; Female; Humans; Hypoxia; Ketam | 1980 |
Vasodilatory effects of ketamine on pulmonary arteries in rats with chronic hypoxic pulmonary hypertension.
Topics: Acetylcholine; Animals; Arginine; Dinoprost; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; | 1995 |
Pulmonary hydraulic impedance responses to hypoxia and hypercapnia in newborn pigs.
Topics: Airway Resistance; Animals; Animals, Newborn; Azaperone; Blood Gas Analysis; Energy Metabolism; Fema | 1994 |
Serotonin 1A-receptor activation suppresses respiratory apneusis in the cat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Female; Hypoxia; Injections, Intraventricular | 1994 |
[Effect of ketamine on hepatic circulation and oxygen metabolism during hypoxia in dog].
Topics: Animals; Hypoxia; Ketamine; Liver Circulation; Oxygen; Rats | 1993 |
Pontile regulation of ventilatory activity in the adult rat.
Topics: Animals; Brain Stem; Female; Hypoxia; Ketamine; Male; Pons; Rats; Rats, Sprague-Dawley; Respiration; | 1993 |
Incidence and magnitude of hypoxaemia with ketamine in a rural African hospital.
Topics: Adolescent; Adult; Altitude; Anesthesia, Intravenous; Child; Child, Preschool; Developing Countries; | 1993 |
Effect of drugs on chemoreceptor responsiveness in fetal sheep.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Chemoreceptor Cells; Fetus; Heart Rate; Hypoxia | 1995 |
Ketamine antagonizes hypoxia-induced dopamine release in rat striatum.
Topics: Animals; Blood Gas Analysis; Dopamine; Dopamine Antagonists; Electrochemistry; Hydrogen-Ion Concentr | 1995 |
Hypoxia-induced dysfunction in developing rat neocortex.
Topics: Aging; Anesthetics, Intravenous; Animals; Calcium; Extracellular Space; Hypoxia; In Vitro Techniques | 1997 |
Electrocortical brain activity during hypoxia and hypotension in anesthetized newborn lambs.
Topics: Anesthesia; Animals; Animals, Newborn; Blood Gas Analysis; Blood Pressure; Brain; Carbon Dioxide; Ca | 1999 |
Ketamine preserves and propofol potentiates hypoxic pulmonary vasoconstriction compared with the conscious state in chronically instrumented dogs.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Cyclooxygenase Inhibitors; Dogs; Hypox | 1999 |
Comparative cardiopulmonary effects of carfentanil-xylazine and medetomidine-ketamine used for immobilization of mule deer and mule deer/white-tailed deer hybrids.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Dissociative; Animal Welfare; Animals; A | 2000 |
Hypoxaemia and suspected pulmonary oedema in a Dorper ewe after diazepam-ketamine induction of anaesthesia.
Topics: Anesthesia; Anesthetics, Combined; Animals; Diazepam; Female; Halothane; Hernia, Ventral; Hypoxia; I | 2000 |
Ketamine sedation for pediatric critical care procedures.
Topics: Adolescent; Adult; Anesthesia; Anesthetics, Dissociative; Child; Child, Preschool; Critical Care; Fe | 2001 |
Active glottal closure during anoxic gasping in lambs.
Topics: Animals; Animals, Newborn; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Electroencephalograph | 2001 |
[Ketamine and L-NAME inhibit NOS and somatostatin mRNA expression induced by altitude hypoxia in the rat hypothalamus].
Topics: Altitude Sickness; Animals; Hypothalamus; Hypoxia; Ketamine; NG-Nitroarginine Methyl Ester; Nitric O | 2000 |
Ketamine abolishes ischemic preconditioning through inhibition of K(ATP) channels in rabbit hearts.
Topics: Animals; Cell Separation; Cytoprotection; Diazoxide; Heart; Hypoxia; In Vitro Techniques; Ischemic P | 2002 |
[Pulmonary hypertension and pulmonary edema caused by intravenous ketamine (author's transl)].
Topics: Anesthesia, General; Coronary Disease; Fentanyl; Humans; Hypertension, Pulmonary; Hypoxia; Injection | 1978 |
Hypoxia-induced vasoconstriction in isolated perfused lungs exposed to injectable or inhalation anesthetics.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Diazepam; Dose-Response Relat | 1977 |
Hypoxic ventilatory drive in dogs during thiopental, ketamine, or pentobarbital anesthesia.
Topics: Anesthesia, Intravenous; Animals; Carbon Dioxide; Dogs; Female; Hypercapnia; Hypoxia; Ketamine; Male | 1975 |
Ketamine/xylazine/butorphanol: a new anesthetic combination for rabbits.
Topics: Anesthesia; Animals; Blood Pressure; Butorphanol; Dose-Response Relationship, Drug; Drug Combination | 1992 |
Treatment with conotoxin, an 'N-type' calcium channel blocker, in neuronal hypoxic-ischemic injury.
Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Hypoxia; Injections; Ischemia; Ketamine | 1990 |
Anoxic injury of CNS white matter: protective effect of ketamine.
Topics: Action Potentials; Animals; Aspartic Acid; Central Nervous System Diseases; Glutamates; Hypoxia; Ket | 1990 |
The pathophysiology of anoxic injury in central nervous system white matter.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Central Nervous System Diseases; Hypo | 1990 |
Ketamine hydrochloride increases survival time during global hypoxia.
Topics: Animals; Hypoxia; Ketamine; Male; Mice; Rats; Rats, Inbred Strains | 1990 |
Synthesis, phencyclidine-like pharmacology, and antiischemic potential of meta-substituted 1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridines.
Topics: Animals; Animals, Newborn; Binding Sites; Brain; Chemical Phenomena; Chemistry; Discrimination, Psyc | 1990 |
Inciting excitotoxic cytocide among central neurons.
Topics: Action Potentials; Animals; Brain; Cell Survival; Chick Embryo; Cholinergic Fibers; Disease Models, | 1986 |
Ketamine protects cultured neocortical neurons from hypoxic injury.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Hypoxia; Ketamine; Mice; Neurons; Sodium C | 1986 |
[Ketamine anesthesia during bronchoscopy in patients with pulmonary tuberculosis].
Topics: Adolescent; Adult; Anesthesia, General; Bronchoscopy; Child; Child, Preschool; Female; Humans; Hypox | 1985 |
Cerebral response to hypocapnia in normal and brain-injured dogs.
Topics: Anesthesia, Intravenous; Angiotensin II; Animals; Blood; Blood Pressure; Brain; Brain Injuries; Carb | 1974 |