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ketamine and Cardiotoxicity

ketamine has been researched along with Cardiotoxicity in 3 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.

Research Excerpts

ExcerptRelevanceReference
"The antioxidant and cardioprotective effects of oleuropein have been reported in several studies; however, its effect on ketamine cardiotoxicity has not been known yet."7.96Protective effect of oleuropein on ketamine-induced cardiotoxicity in rats. ( Aydın, T; Borazan, Y; Çakır, A; Cellat, M; Çömez, MS; Gökçek, İ; Güvenç, M; Özkan, H; Özsoy, ŞY; Türk, E, 2020)
"The antioxidant and cardioprotective effects of oleuropein have been reported in several studies; however, its effect on ketamine cardiotoxicity has not been known yet."3.96Protective effect of oleuropein on ketamine-induced cardiotoxicity in rats. ( Aydın, T; Borazan, Y; Çakır, A; Cellat, M; Çömez, MS; Gökçek, İ; Güvenç, M; Özkan, H; Özsoy, ŞY; Türk, E, 2020)
" To the best of our knowledge, these studies for the first time show that nifedipine and the dietary supplement ALCAR together induce adverse effects while providing evidence on the therapeutic efficacy of subanesthetic doses of ketamine against nifedipine toxicity in vivo."1.56Nifedipine toxicity is exacerbated by acetyl l-carnitine but alleviated by low-dose ketamine in zebrafish in vivo. ( Ali, SF; Dumas, M; Gu, Q; Kanungo, J; Robinson, BL; Tryndyak, V, 2020)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Robinson, BL1
Gu, Q1
Tryndyak, V1
Ali, SF1
Dumas, M1
Kanungo, J1
Çömez, MS1
Cellat, M1
Özkan, H1
Borazan, Y1
Aydın, T1
Gökçek, İ1
Türk, E1
Güvenç, M1
Çakır, A1
Özsoy, ŞY1
Polegato, BF1
Minicucci, MF1
Azevedo, PS1
Carvalho, RF1
Chiuso-Minicucci, F1
Pereira, EJ1
Paiva, SA1
Zornoff, LA1
Okoshi, MP1
Matsubara, BB1
Matsubara, LS1

Other Studies

3 other studies available for ketamine and Cardiotoxicity

ArticleYear
Nifedipine toxicity is exacerbated by acetyl l-carnitine but alleviated by low-dose ketamine in zebrafish in vivo.
    Journal of applied toxicology : JAT, 2020, Volume: 40, Issue:2

    Topics: Acetylcarnitine; Animals; Calcium Channel Blockers; Cardiotoxicity; Embryo, Nonmammalian; Humans; Ke

2020
Protective effect of oleuropein on ketamine-induced cardiotoxicity in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2020, Volume: 393, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Disease Models, Animal; Heart Disea

2020
Acute doxorubicin-induced cardiotoxicity is associated with matrix metalloproteinase-2 alterations in rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:5

    Topics: Animals; Blood Pressure; Cardiotoxicity; Doxorubicin; Echocardiography; Heart; Intercellular Adhesio

2015
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