Page last updated: 2024-10-29

ketamine and Apnea

ketamine has been researched along with Apnea in 42 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Apnea: A transient absence of spontaneous respiration.

Research Excerpts

ExcerptRelevanceReference
" Tracings were analyzed for evidence of apnea, periodic breathing and/or bradycardia by a pulmonologist unaware of the anesthetic technique utilized."9.06Postoperative apnea in former preterm infants: prospective comparison of spinal and general anesthesia. ( Broadman, LM; Fink, R; Hannallah, RS; Rice, LJ; Ruttimann, UE; Welborn, LG, 1990)
" It generally has a reassuring adverse event profile and rarely has been reported to result in apnea."8.12Apnea with ketamine sedation in a patient with severe anorexia nervosa: A case report. ( Joshi, R; Marvin, W, 2022)
" One minute after receiving ketamine, she developed apnea; bag-valve-mask ventilation was initiated, and she received succinylcholine and etomidate and was intubated on the first attempt, without complication."7.85Apnea After Low-Dose Ketamine Sedation During Attempted Delayed Sequence Intubation. ( Driver, BE; Reardon, RF, 2017)
"We describe the characteristics of and predictors for apnea and clinical interventions during emergency department (ED) procedural sedation."7.83Characteristics of and Predictors for Apnea and Clinical Interventions During Procedural Sedation. ( Andolfatto, G; Krauss, BA; Krauss, BS; Mieloszyk, RJ; Monuteaux, MC, 2016)
"We report a rare case of prolonged apnea following administration of ketamine."7.74Prolonged apnea with intramuscular ketamine: a case report. ( Jonnavithula, N; Kulkarni, DK; Ramachandran, G, 2008)
" Complications including apnea, hypotension, hypoxia, nausea, and vomiting, along with gastroenterologist satisfaction and patients' pain score (based on Wong-Baker faces pain assessment scale), were recorded by a checklist."5.51Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial. ( Aghaali, M; Ahmadpour, S; Alemi, F; Aminnejad, R; Hormati, A; Hormati, M; Sabouri, SM; Saeidi, M; Shafiee, H, 2022)
" We therefore sought to summarize the evidence on the level of pain experienced by neonates both during and following procedures; relevant drug-related adverse events, namely episodes of apnea, desaturation, bradycardia, and hypotension; and the effects of combinations of drugs."5.41Non-opioid analgesics for procedural pain in neonates. ( Bruschettini, M; Persad, E; Pizarro, AB, 2023)
" The primary outcome was the occurrence of a respiratory adverse event (desaturation, apnea, or hypoventilation) requiring an intervention by the sedating physician."5.22Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial. ( Bell, A; Ding, M; Ferguson, I; Holdgate, A; New, L; Treston, G, 2016)
"Capnography enables the measurement of end-tidal CO2 and thereby the early detection of apnea, prompting immediate intervention to restore ventilation."5.19Capnographic monitoring of propofol-based sedation during colonoscopy. ( Albert, J; Bojunga, J; Filmann, N; Friedrich-Rust, M; Herrmann, E; Kannengiesser, M; Meckbach, Y; Schroeter, H; Trojan, J; Welte, C; Welte, M; Zeuzem, S, 2014)
"022) were significantly lower, and apnea duration (P < 0."5.17Comparison of effects of propofol and ketamine-propofol mixture (ketofol) on laryngeal mask airway insertion conditions and hemodynamics in elderly patients: a randomized, prospective, double-blind trial. ( Aydogan, MS; Begec, Z; Colak, C; Durmus, M; Erdogan, MA; Ozgul, U; Yucel, A, 2013)
" While oxygen desaturation and apnea were not observed in any of the patients in group PK, there were four patients (11."5.11Comparison of propofol with propofol-ketamine combination in pediatric patients undergoing auditory brainstem response testing. ( Akin, A; Aydogan, H; Boyaci, A; Esmaoglu, A; Gulcu, N; Tosun, Z, 2005)
" Apnea occurred in 1 cat treated with methotrimeprazine, romifidine, and ketamine, suggesting that ventilatory support may be necessary when this protocol is used."5.09A preliminary trial comparison of several anesthetic techniques in cats. ( Cruz, ML; de Castro, GB; Luna, SP; Massone, F; Rosa, AL, 2000)
" Ketamine had no influence on the incidence of apnea after propofol, and the net hemodynamic effects were minimal."5.08Additive interactions between propofol and ketamine when used for anesthesia induction in female patients. ( Gin, T; Hong, W; Hui, TW; Plummer, J; Short, TG; Suen, T, 1995)
" Low-dose intravenous ketamine as the primary anesthetic following premedication with fentanyl and midazolam, and in conjunction with nitrous oxide, appeared to produce less hypoxia, hypercarbia, and apnea than when methohexital was used."5.07A double-blind comparison of low-dose intravenous ketamine and methohexital in adults. ( Anderson, JA; Blankstein, KC, 1991)
" Tracings were analyzed for evidence of apnea, periodic breathing and/or bradycardia by a pulmonologist unaware of the anesthetic technique utilized."5.06Postoperative apnea in former preterm infants: prospective comparison of spinal and general anesthesia. ( Broadman, LM; Fink, R; Hannallah, RS; Rice, LJ; Ruttimann, UE; Welborn, LG, 1990)
" It generally has a reassuring adverse event profile and rarely has been reported to result in apnea."4.12Apnea with ketamine sedation in a patient with severe anorexia nervosa: A case report. ( Joshi, R; Marvin, W, 2022)
" One minute after receiving ketamine, she developed apnea; bag-valve-mask ventilation was initiated, and she received succinylcholine and etomidate and was intubated on the first attempt, without complication."3.85Apnea After Low-Dose Ketamine Sedation During Attempted Delayed Sequence Intubation. ( Driver, BE; Reardon, RF, 2017)
"We describe the characteristics of and predictors for apnea and clinical interventions during emergency department (ED) procedural sedation."3.83Characteristics of and Predictors for Apnea and Clinical Interventions During Procedural Sedation. ( Andolfatto, G; Krauss, BA; Krauss, BS; Mieloszyk, RJ; Monuteaux, MC, 2016)
" In anesthetized mice, in addition to an increased V(e), repeated 100 mg/ml Mch exposures increased both DeltaP(b) and R(aw) and decreased f to apnea in 10 min."3.74End-expiratory and tidal volumes measured in conscious mice using single projection x-ray images. ( Houtz, PK; Lai, YL; Lai-Fook, SJ, 2008)
"We report a rare case of prolonged apnea following administration of ketamine."3.74Prolonged apnea with intramuscular ketamine: a case report. ( Jonnavithula, N; Kulkarni, DK; Ramachandran, G, 2008)
" The adverse event (AE) rate was 18% and included apnea (10%), inadequate sedation (3%), bradycardia (2%), desaturation (1%), hypotension (1%) and bag-valve-mask use (1%)."3.73Emergency department procedural sedation and analgesia: A Canadian Community Effectiveness and Safety Study (ACCESS). ( Mensour, M; Michaud, J; Pineau, R; Sahai, V, 2006)
" Few side effects were observed during the trials, aside from mild tremors caused by ketamine, and respiratory depression or prolonged apnea caused by tiletamine-zolazepam."3.71Response of wild subantarctic fur seal (Arctocephalus tropicalis) females to ketamine and tiletamine-zolazepam anesthesia. ( Beauplet, G; Dabin, W; Guinet, C, 2002)
"4%: airway malalignment (n = 7), laryngospasm (n = 4), apnea (n = 2), and respiratory depression (n = 1)."3.70Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases. ( Garrett, W; Green, SM; Harris, T; Hestdalen, R; Ho, M; Hopkins, GA; Lynch, EL; Rothrock, SG; Westcott, K, 1998)
" Induction doses of ketamine 1 hour after HD exposure resulted in periods of profound apnea, with continued respiratory distress for the next 2 hours."3.70Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard. ( Conley, J; Hamilton, M; Hunter, K; Lundy, P; Sawyer, TW, 2000)
" After administration of intramuscular ketamine for sedation, the patient was observed to experience one ineffective respiration followed by a period of apnea."3.68Respiratory arrest following intramuscular ketamine injection in a 4-year-old child. ( Santer, LJ; Smith, JA, 1993)
"Xylazine alone was administered to 34 leopard seals."1.28Immobilisation of southern elephant seals and leopard seals with cyclohexamine anaesthetics and xylazine. ( Burton, HR; Mitchell, PJ, 1991)
"Propofol anaesthesia was characterised by smooth rapid induction and good muscle relaxation but was only of short duration, ranging from two to seven minutes, and seemed to cause a marked respiratory depression."1.28Preliminary studies on the use of propofol in the domestic pigeon (Columba livia). ( Cooper, JE; Fitzgerald, G, 1990)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19904 (9.52)18.7374
1990's17 (40.48)18.2507
2000's11 (26.19)29.6817
2010's7 (16.67)24.3611
2020's3 (7.14)2.80

Authors

AuthorsStudies
Aminnejad, R1
Hormati, A1
Shafiee, H1
Alemi, F1
Hormati, M1
Saeidi, M1
Ahmadpour, S1
Sabouri, SM1
Aghaali, M1
Persad, E1
Pizarro, AB1
Bruschettini, M1
Joshi, R1
Marvin, W1
Shiber, J1
Friedrich-Rust, M1
Welte, M1
Welte, C1
Albert, J1
Meckbach, Y1
Herrmann, E1
Kannengiesser, M1
Trojan, J1
Filmann, N1
Schroeter, H1
Zeuzem, S1
Bojunga, J1
Ferguson, I1
Bell, A1
Treston, G1
New, L1
Ding, M1
Holdgate, A1
Krauss, BS1
Andolfatto, G1
Krauss, BA1
Mieloszyk, RJ1
Monuteaux, MC1
Driver, BE1
Reardon, RF1
Xue, FS1
Liao, X1
Xu, YC1
Yang, QY1
Marcos Vidal, JM1
Bermejo González, JC1
Baticón Escudero, PM1
Erdogan, MA1
Begec, Z1
Aydogan, MS1
Ozgul, U1
Yucel, A1
Colak, C1
Durmus, M1
Dabin, W1
Beauplet, G1
Guinet, C1
Castilla, M1
Jerez, M1
Llácer, M1
Martinez, S1
Akin, A1
Esmaoglu, A1
Tosun, Z1
Gulcu, N1
Aydogan, H1
Boyaci, A1
Budzińska, K1
Mensour, M1
Pineau, R1
Sahai, V1
Michaud, J1
Lai-Fook, SJ1
Houtz, PK1
Lai, YL1
Moser, B1
Röggla, G1
Jonnavithula, N1
Kulkarni, DK1
Ramachandran, G1
Hui, TW1
Short, TG1
Hong, W1
Suen, T1
Gin, T1
Plummer, J1
Joly, LM1
Benhamou, D1
Schultz, CH1
Green, SM3
Rothrock, SG3
Smith, JA1
Santer, LJ1
Mitchell, RK1
Koury, SI1
Stone, CK1
Litman, RS1
Lynch, EL1
Ho, M1
Harris, T1
Hestdalen, R1
Hopkins, GA1
Garrett, W1
Westcott, K1
Cruz, ML1
Luna, SP1
de Castro, GB1
Massone, F1
Rosa, AL1
Conley, J1
Hunter, K1
Lundy, P1
Hamilton, M1
Sawyer, TW1
Mitchell, PJ1
Burton, HR1
Jahangir, SM1
Rahman, K1
Blankstein, KC1
Anderson, JA1
Webster, AC1
McKishnie, JD1
Kenyon, CF1
Marshall, DG1
Tashiro, C1
Matsui, Y1
Nakano, S1
Ueyama, H1
Nishimura, M1
Oka, N1
Rasch, DK1
Gurkowski, MA1
Park, MK1
Welborn, LG1
Rice, LJ1
Hannallah, RS1
Broadman, LM1
Ruttimann, UE1
Fink, R1
Fitzgerald, G1
Cooper, JE1
Pokorski, M1
Sieradzan, B1
Karczewski, W1
van Wijhe, M1
Stricker, BH1
Rejger, VS1
Coppel, DL1
Dundee, JW1
Lockhart, CH1
Jenkins, JJ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Observational Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio at the Emergency Department of a Tertiary Hospital[NCT04028141]61 participants (Actual)Observational2018-02-01Completed
Intravenous Sedation and Analgesia Using Propofol, Fentanyl and Ketamine (PFK) Versus General Anesthesia in Minor Urological Procedures.[NCT04285528]200 participants (Actual)Interventional2019-04-17Completed
Comparison of Ketamine Versus Co-Administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department[NCT01387139]Phase 3183 participants (Actual)Interventional2011-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Efficacy of Sedation

"Efficacy is defined as:~The patient does not have unpleasant recall of the procedure.~The patient did not experience sedation-related adverse events resulting in abandonment of the procedure or a permanent complication or an unplanned admission to the hospital or prolonged emergency department (ED) observation~The patient did not actively resist or require physical restraint for completion of the procedure. The need for minimal redirection of movements should not be considered as active resistance or physical restraint.~The procedure was successful" (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour

Interventionparticipants (Number)
Ketamine Alone97
Ketamine Co-Administered With Propofol81

Nurse Satisfaction

Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour

Interventionunits on a scale (Median)
Ketamine Alone10
Ketamine Co-Administered With Propofol8

Parent Satisfaction

Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour

Interventionunits on a scale (1-10) (Median)
Ketamine Alone10
Ketamine Co-Administered With Propofol10

Physician Performing Procedure Satisfaction

Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour

Interventionunits on a scale (Median)
Ketamine Alone9
Ketamine Co-Administered With Propofol8

Recovery Time

Time until the patient has a Vancouver Sedation Recovery Scale Score of 18 or greater. (NCT01387139)
Timeframe: Once Vancouver Sedation Recovery Scale Score reaches 18 or greater, on average less than 1 hour

Interventionminutes (Median)
Ketamine Alone44
Ketamine Co-Administered With Propofol43.5

Frequency of Adverse Events

We will record all adverse events during the sedation, and then perform a follow-up call to determine if any additional adverse events occured after discharge. (NCT01387139)
Timeframe: From enrollment through completion of follow-up, up to 7 days

,
Interventionparticipants (Number)
Respiratory depressionCardiovascular eventvomiting/retchingUnpleasant recovery reaction
Ketamine Alone121214
Ketamine Co-Administered With Propofol150182

Reviews

1 review available for ketamine and Apnea

ArticleYear
Non-opioid analgesics for procedural pain in neonates.
    The Cochrane database of systematic reviews, 2023, 04-04, Volume: 4

    Topics: Aged; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Apnea; Body Wei

2023

Trials

10 trials available for ketamine and Apnea

ArticleYear
Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial.
    CNS & neurological disorders drug targets, 2022, Volume: 21, Issue:8

    Topics: Apnea; Colonoscopy; Dexmedetomidine; Double-Blind Method; Fentanyl; Humans; Hypnotics and Sedatives;

2022
Capnographic monitoring of propofol-based sedation during colonoscopy.
    Endoscopy, 2014, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Apnea; Body Mass Index; Capnography; Colono

2014
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
    Annals of emergency medicine, 2016, Volume: 68, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr

2016
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
    Annals of emergency medicine, 2016, Volume: 68, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr

2016
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
    Annals of emergency medicine, 2016, Volume: 68, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr

2016
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
    Annals of emergency medicine, 2016, Volume: 68, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr

2016
Comparison of effects of propofol and ketamine-propofol mixture (ketofol) on laryngeal mask airway insertion conditions and hemodynamics in elderly patients: a randomized, prospective, double-blind trial.
    Journal of anesthesia, 2013, Volume: 27, Issue:1

    Topics: Aged; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetics, Intravenous; Apnea; Blood Pres

2013
Comparison of propofol with propofol-ketamine combination in pediatric patients undergoing auditory brainstem response testing.
    International journal of pediatric otorhinolaryngology, 2005, Volume: 69, Issue:11

    Topics: Adolescent; Anesthetics, Intravenous; Apnea; Blood Pressure; Child; Child, Preschool; Drug Combinati

2005
Additive interactions between propofol and ketamine when used for anesthesia induction in female patients.
    Anesthesiology, 1995, Volume: 82, Issue:3

    Topics: Adult; Age Factors; Anesthesia, Intravenous; Apnea; Blood Pressure; Body Weight; Dose-Response Relat

1995
Ventilation during total intravenous anaesthesia with ketamine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:3

    Topics: Adult; Age Factors; Airway Obstruction; Anesthesia Recovery Period; Anesthesia, Intravenous; Apnea;

1994
A preliminary trial comparison of several anesthetic techniques in cats.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2000, Volume: 41, Issue:6

    Topics: Anesthesia, General; Anesthetics, Dissociative; Animals; Apnea; Cats; Drug Therapy, Combination; Fem

2000
A double-blind comparison of low-dose intravenous ketamine and methohexital in adults.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1991, Volume: 49, Issue:5

    Topics: Adolescent; Adult; Amnesia; Anesthesia, Dental; Apnea; Carbon Dioxide; Double-Blind Method; Female;

1991
Postoperative apnea in former preterm infants: prospective comparison of spinal and general anesthesia.
    Anesthesiology, 1990, Volume: 72, Issue:5

    Topics: Anesthesia, General; Anesthesia, Spinal; Apnea; Bradycardia; Hernia, Inguinal; Humans; Infant, Newbo

1990

Other Studies

31 other studies available for ketamine and Apnea

ArticleYear
Apnea with ketamine sedation in a patient with severe anorexia nervosa: A case report.
    Eating and weight disorders : EWD, 2022, Volume: 27, Issue:1

    Topics: Adolescent; Anesthesia; Anesthetics, Dissociative; Anorexia Nervosa; Apnea; Autism Spectrum Disorder

2022
Ketamine Causing Apnea?
    Annals of emergency medicine, 2017, Volume: 69, Issue:5

    Topics: Apnea; Humans; Ketamine

2017
Characteristics of and Predictors for Apnea and Clinical Interventions During Procedural Sedation.
    Annals of emergency medicine, 2016, Volume: 68, Issue:5

    Topics: Adult; Aged; Apnea; Capnography; Conscious Sedation; Female; Heart Rate; Humans; Hypnotics and Sedat

2016
Apnea After Low-Dose Ketamine Sedation During Attempted Delayed Sequence Intubation.
    Annals of emergency medicine, 2017, Volume: 69, Issue:1

    Topics: Apnea; Conscious Sedation; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Int

2017
Sedation and anesthesia for fiberoptic intubation in management of pediatric difficult airways.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:12

    Topics: Adolescent; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetics, Inhalation; Apnea; Child

2008
[Noninvasive ventilation through a nasal mask to sedate a man with amyotrophic lateral sclerosis during percutaneous endoscopic gastrostomy].
    Revista espanola de anestesiologia y reanimacion, 2011, Volume: 58, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Apnea; Deep Sedation; Endoscopy; Enteral Nutrition; Gastrostomy; Huma

2011
Response of wild subantarctic fur seal (Arctocephalus tropicalis) females to ketamine and tiletamine-zolazepam anesthesia.
    Journal of wildlife diseases, 2002, Volume: 38, Issue:4

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Animals; Antarctic Regions; Anti-Anxiety Agents; A

2002
Anaesthetic management in a neonate with congenital complete heart block.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:2

    Topics: Analgesics; Anesthesia, General; Anesthetics, Inhalation; Apnea; Heart Block; Heart Rate; Humans; In

2004
Divergent effects of bicuculline and picrotoxin on ketamine-induced apneustic breathing.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56 Suppl 4

    Topics: Animals; Apnea; Bicuculline; Blood Pressure; Cats; Disease Models, Animal; GABA Antagonists; GABA-A

2005
Emergency department procedural sedation and analgesia: A Canadian Community Effectiveness and Safety Study (ACCESS).
    CJEM, 2006, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Apnea; Blood Gas Monitoring, Transcutaneous; Bradycardia; Cana

2006
End-expiratory and tidal volumes measured in conscious mice using single projection x-ray images.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 104, Issue:2

    Topics: Administration, Inhalation; Aerosols; Airway Resistance; Anesthetics, Dissociative; Animals; Apnea;

2008
Emergency anaesthesia at high altitude.
    Anaesthesia, 2008, Volume: 63, Issue:1

    Topics: Altitude; Anesthetics, Dissociative; Apnea; Emergencies; Humans; Hypnotics and Sedatives; Ketamine

2008
Prolonged apnea with intramuscular ketamine: a case report.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:4

    Topics: Analgesics; Apnea; Emergency Treatment; Female; Humans; Infant; Injections, Intramuscular; Intubatio

2008
Intramuscular ketamine and apnea.
    Annals of emergency medicine, 1994, Volume: 23, Issue:1

    Topics: Apnea; Child, Preschool; Humans; Injections, Intramuscular; Injections, Intravenous; Ketamine

1994
Intramuscular ketamine and apnea.
    Annals of emergency medicine, 1994, Volume: 23, Issue:1

    Topics: Apnea; Child, Preschool; Humans; Injections, Intramuscular; Ketamine

1994
Respiratory arrest following intramuscular ketamine injection in a 4-year-old child.
    Annals of emergency medicine, 1993, Volume: 22, Issue:3

    Topics: Apnea; Child, Preschool; Ear Canal; Foreign Bodies; Humans; Injections, Intramuscular; Ketamine; Mal

1993
Respiratory arrest after intramuscular ketamine in a 2-year-old child.
    The American journal of emergency medicine, 1996, Volume: 14, Issue:6

    Topics: Anesthetics, Dissociative; Apnea; Child, Preschool; Ear Canal; Female; Foreign Bodies; Humans; Ketam

1996
Transient apnea with intramuscular ketamine.
    The American journal of emergency medicine, 1997, Volume: 15, Issue:4

    Topics: Anesthetics, Dissociative; Apnea; Child; Humans; Ketamine

1997
Apnea and oxyhemoglobin desaturation after intramuscular ketamine administration in a 2-year-old child.
    The American journal of emergency medicine, 1997, Volume: 15, Issue:5

    Topics: Anesthetics, Dissociative; Apnea; Child, Preschool; Conscious Sedation; Humans; Injections, Intramus

1997
Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases.
    Annals of emergency medicine, 1998, Volume: 31, Issue:6

    Topics: Adolescent; Affective Symptoms; Anesthetics, Dissociative; Apnea; Child; Child, Preschool; Conscious

1998
Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard.
    Military medicine, 2000, Volume: 165, Issue:8

    Topics: Anesthesia, General; Anesthetics; Animals; Apnea; Chemical Warfare; Disease Models, Animal; Drug Eva

2000
Immobilisation of southern elephant seals and leopard seals with cyclohexamine anaesthetics and xylazine.
    The Veterinary record, 1991, Oct-12, Volume: 129, Issue:15

    Topics: Anesthetics; Animals; Apnea; Immobilization; Ketamine; Pneumonia, Aspiration; Seals, Earless; Tileta

1991
Prolonged apnoea, trismus and ketamine.
    Anaesthesia, 1991, Volume: 46, Issue:12

    Topics: Apnea; Child; Humans; Injections, Intramuscular; Ketamine; Male; Trismus

1991
Spinal anaesthesia for inguinal hernia repair in high-risk neonates.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:3

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Spinal; Apnea; Female; Halothane; Herni

1991
Respiratory outcome in extremely premature infants following ketamine anaesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:3

    Topics: Age Factors; Aminophylline; Anesthesia, Intravenous; Apnea; Birth Weight; Gestational Age; Humans; I

1991
Apnea during prostaglandin infusion caused by intramuscular ketamine.
    Journal of cardiothoracic anesthesia, 1990, Volume: 4, Issue:6

    Topics: Alprostadil; Apnea; Drug Interactions; Humans; Infant, Newborn; Injections, Intramuscular; Ketamine;

1990
Preliminary studies on the use of propofol in the domestic pigeon (Columba livia).
    Research in veterinary science, 1990, Volume: 49, Issue:3

    Topics: Anesthesia; Animals; Animals, Domestic; Apnea; Bird Diseases; Columbidae; Female; Heart Rate; Inject

1990
Apneustic respiration of ketamine is not antagonized by naloxone in the cat.
    The Japanese journal of physiology, 1987, Volume: 37, Issue:4

    Topics: Animals; Apnea; Cats; Ketamine; Naloxone; Receptors, Opioid; Respiration

1987
Prolonged apnoea with ketamine.
    British journal of anaesthesia, 1986, Volume: 58, Issue:5

    Topics: Anesthesia, Intravenous; Apnea; Female; Humans; Infant; Ketamine

1986
Ketamine anaesthesia for cardiac catheterisation.
    Anaesthesia, 1972, Volume: 27, Issue:1

    Topics: Acid-Base Equilibrium; Anesthesia, General; Anesthetics; Apnea; Atropine; Blood Pressure; Carbon Dio

1972
Ketamine-induced apnea in patients with increased intracranial pressure.
    Anesthesiology, 1972, Volume: 37, Issue:1

    Topics: Anesthesia, General; Anesthetics; Apnea; Cyclohexanes; Female; Humans; Hydrocephalus; Infant; Infant

1972