ketamine and Anorexia
ketamine has been researched along with Anorexia in 4 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study tested the effects of ketamine on vulnerability of female adolescent mice to activity-based anorexia (ABA)." | 7.88 | Single injection of ketamine during mid-adolescence promotes long-lasting resilience to activity-based anorexia of female mice by increasing food intake and attenuating hyperactivity as well as anxiety-like behavior. ( Aoki, C; Chen, YW; Sherpa, AD, 2018) |
| "This study tested the effects of ketamine on vulnerability of female adolescent mice to activity-based anorexia (ABA)." | 3.88 | Single injection of ketamine during mid-adolescence promotes long-lasting resilience to activity-based anorexia of female mice by increasing food intake and attenuating hyperactivity as well as anxiety-like behavior. ( Aoki, C; Chen, YW; Sherpa, AD, 2018) |
| "There was no external evidence of trauma." | 2.40 | Review of exertional rhabdomyolysis and a case in a rhesus monkey (Macaca mulatta). ( Chrisp, CE; Dysko, RC; Reuter, JD, 1998) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Temizer, R | 1 |
| Chen, YW | 2 |
| Aoki, C | 2 |
| Sherpa, AD | 1 |
| Mills, IH | 1 |
| Park, GR | 1 |
| Manara, AR | 1 |
| Merriman, RJ | 1 |
| Reuter, JD | 1 |
| Dysko, RC | 1 |
| Chrisp, CE | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Starving for Energy - A Pilot Study to Test Ketone Derived Energy in Eating Disorders[NCT05507008] | 40 participants (Anticipated) | Interventional | 2022-10-13 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
1 review available for ketamine and Anorexia
| Article | Year |
|---|---|
Review of exertional rhabdomyolysis and a case in a rhesus monkey (Macaca mulatta).
Topics: Alanine Transaminase; Animals; Anorexia; Aspartate Aminotransferases; Atropine; Biopsy; Cefazolin; C | 1998 |
Trials
1 trial available for ketamine and Anorexia
| Article | Year |
|---|---|
Treatment of compulsive behaviour in eating disorders with intermittent ketamine infusions.
Topics: Adult; Anesthetics, Dissociative; Anorexia; Chronic Disease; Compulsive Personality Disorder; Drug A | 1998 |
Other Studies
2 other studies available for ketamine and Anorexia
| Article | Year |
|---|---|
Individual differences in the positive outcome from adolescent ketamine treatment in a female mouse model of anorexia nervosa involve drebrin A at excitatory synapses of the medial prefrontal cortex.
Topics: Animals; Anorexia; Anorexia Nervosa; Cytoplasm; Disease Models, Animal; Female; gamma-Aminobutyric A | 2023 |
Single injection of ketamine during mid-adolescence promotes long-lasting resilience to activity-based anorexia of female mice by increasing food intake and attenuating hyperactivity as well as anxiety-like behavior.
Topics: Adolescent; Analgesics; Animals; Anorexia; Anxiety; Disease Models, Animal; Eating; Female; Humans; | 2018 |