Page last updated: 2024-08-21

kainic acid and Ache

kainic acid has been researched along with Ache in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199011 (23.91)18.7374
1990's15 (32.61)18.2507
2000's13 (28.26)29.6817
2010's7 (15.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cortés Castell, E; Gil Guillén, V; Rizo Baeza, MM; Sirvent Segura, E; Torro Montell, L; Veciana Galindo, C1
Jiang, Y; Li, G; Liu, J; Ma, Y; Tian, S; Tian, Y; Yan, L; Zhou, C1
Bali, KK; Gritsch, S; Kuner, R; Vardeh, D1
Handy, C; Lin, CL; Lin, Y; Roman, K; Stephens, RL; Tian, G; Travers, JB1
Guan, X; Lu, W; Petralia, RS; Rothstein, JD; Tao, YX; Yaster, M1
Chen, DF; Lin, Y; Roman, K; Stephens, RL; Wang, ZG; Yang, M1
Borsotto, M; Coppola, T; Gandin, C; Heurteaux, C; Labbal, F; Mazella, J; Moha Ou Maati, H; Veyssiere, J; Widmann, C1
Diuzhikova, NA; Levina, AS; Savenko, IuN; Vaĭdo, AI1
Al-Amin, HA; Apkarian, AV; Atweh, SF; Baliki, M; Hawwa, N; Jabbur, SJ; Jaber, M; Saadé, NE1
Jones, TL; Sorkin, LS1
Hamanaka, N; Ito, S; Matsumura, S; Minami, T; Nishizawa, M; Sasaguri, Y1
Carlton, SM; Du, J; Zhou, S1
Calixto, JB; Gadotti, VM; Paszcuk, AF; Rodrigues, AL; Santos, AR; Tibola, D1
Farooqui, AA; Horrocks, LA; Ong, WY1
Choi, OS; Choi, SM; Ham, YO; Kwon, MS; Lee, JY; Seo, YJ; Shim, EJ; Suh, HW1
Furuta, K; Ito, S; Mabuchi, T; Maeda, M; Minami, T; Soen, M; Suzuki, M; Tatsumi, S1
Abay, EO; Go, VL; Micevych, PE; Schmauss, C; Yaksh, TL1
Lin, MT; Tsay, BL; Wu, JJ1
Chan, SH; Lai, YY1
Fukui, S; Hasegawa, T; Iyo, M; Maeda, Y; Nabeshima, T; Yamada, K1
Cumberbatch, MJ; Headley, PM; Herrero, JF1
Larson, AA; Sun, X1
Bonasera, L; Carlton, SM; Zhou, S1
Atweh, SF; Bahuth, NB; Jabbur, SJ; Saadé, NE1
Grandy, DK; Grisel, JE; Morgan, MM; Robbins, CS1
Budai, D; Fields, HL1
Song, XJ; Zhao, ZQ1
Dickinson-Anson, H; Dyck, RH; Gage, FH; Heinemann, SF; Malkmus, SA; Maron, C; O'Gorman, S; O'Leary, L; Pérez-Otaño, I; Sailer, A; Schiffer, HH; Swanson, GT; Yaksh, TL1
Choi, MR; Chung, KM; Huh, SO; Kim, YH; Lee, KC; Song, DK; Suh, HW1
Cutler, TD; Dougherty, PM; Fuchs, PN; LaBuda, CJ1
Cheng, JK; Lin, CR; Marsala, M; Tsai, PS; Wen, GH; Yang, LC1
Chang, YC; Cheng, TJ; Chou, AK; Kao, CH; Lin, CR; Tan, PH; Wen, ZH; Wong, CS; Yang, LC1
Jensen, TS; Yaksh, TL1
Grunwerg, BS; Krauthamer, GM; Krol, JG1
Coderre, TJ; Melzack, R1
Larson, AA; Skilling, SR; Smullin, DH1
Cowan, A; Larson, AA; Murray, CW1
Urca, G; Urca, R1
Bossut, D; Frenk, H; Mayer, DJ3
Bossut, D; Frenk, H; Mayer, DJ; Urca, G1
Aanonsen, LM; Wilcox, GL1
Jacquet, YF1
Lin, MT; Liu, MY; Su, CF1
Gao, DM; Lu, ZQ; Sun, DY; Wang, WQ1

Reviews

1 review(s) available for kainic acid and Ache

ArticleYear
Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders.
    Pharmacological reviews, 2006, Volume: 58, Issue:3

    Topics: Animals; Blood Proteins; Brain; Brain Injuries; Humans; Kainic Acid; Models, Biological; Nervous System Diseases; Neurons; Pain; Phospholipases A; Phospholipases A2

2006

Other Studies

45 other study(ies) available for kainic acid and Ache

ArticleYear
[Effect on zebrafish neurodevelopment and neuroprotection of a polyphenolic extract olive seeds].
    Nutricion hospitalaria, 2014, Aug-01, Volume: 30, Issue:2

    Topics: Animals; Kainic Acid; Nervous System; Neuroprotective Agents; Olea; Pain; Phytotherapy; Plant Extracts; Polyphenols; Seeds; Zebrafish

2014
Effects on Spatial Cognition and Nociceptive Behavior Following Peripheral Nerve Injury in Rats with Lesion of the Striatal Marginal Division Induced by Kainic Acid.
    Neurochemical research, 2015, Volume: 40, Issue:11

    Topics: Animals; Behavior, Animal; Corpus Striatum; Excitatory Amino Acid Antagonists; Inflammation Mediators; Kainic Acid; Male; Maze Learning; Nociception; Pain; Peripheral Nerve Injuries; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Space Perception; Substance P

2015
Functional characterization of a mouse model for central post-stroke pain.
    Molecular pain, 2016, Volume: 12

    Topics: Animals; Collagenases; Disease Models, Animal; Hyperalgesia; Kainic Acid; Lidocaine; Mice, Inbred C57BL; Microinjections; Nerve Fibers, Unmyelinated; Pain; Sensation; Spinal Cord; Stroke; Thalamus; TRPV Cation Channels; Ventral Thalamic Nuclei

2016
Increased glial glutamate transporter EAAT2 expression reduces visceral nociceptive response in mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:1

    Topics: Acetic Acid; Animals; Behavior, Animal; Ceftriaxone; Colon; Disease Models, Animal; Ethanol; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Humans; Hyperalgesia; Kainic Acid; Mice; Mice, Transgenic; Pain; Pain Measurement; Pain Threshold; Pressure; Up-Regulation

2009
Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvant.
    Anesthesiology, 2011, Volume: 114, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Disease Models, Animal; Formaldehyde; Freund's Adjuvant; Glutamic Acid; Inflammation; Kainic Acid; Male; Nicotinic Acids; Pain; Phosphoserine; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord

2011
GLT-1 overexpression attenuates bladder nociception and local/cross-organ sensitization of bladder nociception.
    American journal of physiology. Renal physiology, 2011, Volume: 300, Issue:6

    Topics: Analysis of Variance; Animals; Blotting, Western; Ceftriaxone; Colon; Electromyography; Excitatory Amino Acid Transporter 2; Female; Kainic Acid; Mice; Pain; Pain Perception; Urinary Bladder

2011
Spadin as a new antidepressant: absence of TREK-1-related side effects.
    Neuropharmacology, 2012, Volume: 62, Issue:1

    Topics: Animals; Antidepressive Agents; Biophysical Phenomena; Blood Glucose; Brain Infarction; CD8 Antigens; Cell Line, Transformed; Chlorocebus aethiops; Convulsants; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Eating; Electric Stimulation; Green Fluorescent Proteins; Hindlimb Suspension; Humans; Infarction, Middle Cerebral Artery; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Pain; Pain Measurement; Patch-Clamp Techniques; Pentylenetetrazole; Peptides; Potassium Channels; Potassium Channels, Tandem Pore Domain; Seizures; Swimming; Transfection

2012
[Kainate receptors in the hippocampus of rat strains with different levels of the nervous system excitability].
    Morfologiia (Saint Petersburg, Russia), 2011, Volume: 139, Issue:3

    Topics: Animals; CA3 Region, Hippocampal; Immunohistochemistry; Kainic Acid; Nervous System Physiological Phenomena; Neurons; Pain; Rats; Rats, Inbred Strains; Receptors, Kainic Acid; Species Specificity; Stress, Psychological

2011
Attenuation of neuropathic manifestations by local block of the activities of the ventrolateral orbito-frontal area in the rat.
    Neuroscience, 2003, Volume: 120, Issue:4

    Topics: Adrenergic Agents; Anesthetics, Local; Animals; Cold Temperature; Disease Models, Animal; Electricity; Excitatory Amino Acid Agonists; Female; Hindlimb; Hot Temperature; Hyperalgesia; Kainic Acid; Lidocaine; Mononeuropathies; Nerve Block; Oxidopamine; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reference Values; Somatosensory Cortex

2003
Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate receptors mediate development, but not maintenance, of secondary allodynia evoked by first-degree burn in the rat.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Burns; Calcium; Disease Models, Animal; Excitatory Amino Acid Antagonists; Injections, Spinal; Kainic Acid; Motor Cortex; Pain; Pain Threshold; Rats; Receptors, AMPA; Receptors, Kainic Acid; Spider Venoms

2004
Acute and late effects on induction of allodynia by acromelic acid, a mushroom poison related structurally to kainic acid.
    British journal of pharmacology, 2004, Volume: 142, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basidiomycota; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutamates; Heterocyclic Compounds; Indoles; Injections, Spinal; Japan; Kainic Acid; Lumbosacral Region; Male; Mice; Mice, Inbred Strains; Mushroom Poisoning; Oximes; Pain; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Time Factors

2004
Kainate-induced excitation and sensitization of nociceptors in normal and inflamed rat glabrous skin.
    Neuroscience, 2006, Volume: 137, Issue:3

    Topics: Animals; Axons; Behavior, Animal; Calcitonin Gene-Related Peptide; Dermatitis; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Habituation, Psychophysiologic; Hot Temperature; Kainic Acid; Male; Nociceptors; Pain; Peripheral Nerves; Physical Stimulation; Rats; Rats, Sprague-Dawley; Skin; Stimulation, Chemical

2006
Contribution of spinal glutamatergic receptors to the antinociception caused by agmatine in mice.
    Brain research, 2006, Jun-06, Volume: 1093, Issue:1

    Topics: Agmatine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Neuroprotective Agents; Nociceptors; Pain; Receptors, Glutamate; Spinal Cord

2006
The intracerebroventricular kainic acid-induced damage affects animal nociceptive behavior.
    Brain research bulletin, 2007, Jul-12, Volume: 73, Issue:4-6

    Topics: Animals; Behavior, Animal; Cytokines; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Mice; Neurons; Pain; Pain Measurement; Substance P

2007
A synthetic kainoid, (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid (PSPA-1) serves as a novel anti-allodynic agent for neuropathic pain.
    European journal of pharmacology, 2007, Dec-01, Volume: 575, Issue:1-3

    Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hyperalgesia; Immunohistochemistry; Inflammation; Kainic Acid; Mice; Mononeuropathies; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nociceptors; Pain; Spinal Cord; Time Factors

2007
Pharmacological studies on the application, disposition, and release of neurotensin in the spinal cord.
    Annals of the New York Academy of Sciences, 1982, Volume: 400

    Topics: Animals; Capsaicin; Cats; Histocytochemistry; Kainic Acid; Neurotensin; Nociceptors; Pain; Radioimmunoassay; Reaction Time; Spinal Cord; Spinal Nerve Roots; Substance P; Tissue Distribution

1982
Effects of kainic acid injections in the striatum on physiologic and behavioral functions in conscious rats.
    Experimental neurology, 1984, Volume: 83, Issue:1

    Topics: Animals; Apomorphine; Basal Metabolism; Behavior, Animal; Body Temperature; Corpus Striatum; Dopamine; Kainic Acid; Male; Movement; Pain; Pyrrolidines; Rats; Rats, Inbred Strains; Reflex

1984
Antagonization of clonidine- and morphine-promoted antinociception by kainic acid lesion of nucleus reticularis gigantocellularis in the rat.
    Experimental neurology, 1982, Volume: 78, Issue:1

    Topics: Animals; Brain Diseases; Clonidine; Kainic Acid; Male; Morphine; Nociceptors; Pain; Rats; Rats, Inbred Strains; Reticular Formation

1982
Inhibitory effects of salmon calcitonin on the tail-biting and scratching behavior induced by substance P and three excitatory amino acids.
    Journal of neural transmission. General section, 1994, Volume: 96, Issue:2

    Topics: Afferent Pathways; Animals; Calcitonin; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Injections, Intraventricular; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Pain; Pain Measurement; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurokinin-1; Spinal Cord; Substance P; Tail

1994
Exposure of rat spinal neurones to NMDA, AMPA and kainate produces only short-term enhancements of responses to noxious and non-noxious stimuli.
    Neuroscience letters, 1994, Nov-07, Volume: 181, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Hot Temperature; Kainic Acid; Male; N-Methylaspartate; Neurons; Nociceptors; Pain; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Time Factors

1994
The amino-terminus of substance P mimics and MK-801 attenuates the effects of capsaicin on nociception and kainic acid-induced behavior in the mouse.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Analysis of Variance; Animals; Capsaicin; Dizocilpine Maleate; Haloperidol; Kainic Acid; Male; Mice; Pain; Peptide Fragments; Piperazines; Receptors, N-Methyl-D-Aspartate; Substance P

1993
Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats.
    Neuroreport, 1996, Mar-22, Volume: 7, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Hindlimb; Kainic Acid; Logistic Models; Male; N-Methylaspartate; Pain; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

1996
Augmentation of nociceptive reflexes and chronic deafferentation pain by chemical lesions of either dopaminergic terminals or midbrain dopaminergic neurons.
    Brain research, 1997, Mar-14, Volume: 751, Issue:1

    Topics: Animals; Behavior, Animal; Chronic Disease; Denervation; Dopamine; Excitatory Amino Acid Agonists; Female; Kainic Acid; Ligation; Male; Microinjections; Neostriatum; Nerve Endings; Neurons; Nociceptors; Oxidopamine; Pain; Rats; Rats, Sprague-Dawley; Reflex; Sciatic Nerve; Substantia Nigra; Sympatholytics; Ventral Tegmental Area

1997
Antinociception mediated by the periaqueductal gray is attenuated by orphanin FQ.
    Neuroreport, 1997, Nov-10, Volume: 8, Issue:16

    Topics: Animals; Brain Mapping; Kainic Acid; Male; Microinjections; Morphine; Neurons; Nociceptin; Opioid Peptides; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid

1997
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
    Journal of neurophysiology, 1998, Volume: 79, Issue:2

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail

1998
Involvement of NMDA and non-NMDA receptors in transmission of spinal visceral nociception in cat.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Excitatory Amino Acid Agonists; Female; Kainic Acid; Male; N-Methylaspartate; Nociceptors; Pain; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Splanchnic Nerves; Viscera

1999
Generation and analysis of GluR5(Q636R) kainate receptor mutant mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Oct-15, Volume: 19, Issue:20

    Topics: Animals; Behavior, Animal; Electrophysiology; Ganglia, Spinal; Kainic Acid; Mice; Mice, Mutant Strains; Neurons; Pain; Receptors, Kainic Acid; Recombination, Genetic; Reference Values; Seizures

1999
Differential modulatory roles of cholera toxin and pertussis toxin in the regulation of pain responses induced by excitatory amino acids administered intrathecally in mice.
    Brain research, 2000, Jun-09, Volume: 867, Issue:1-2

    Topics: Adjuvants, Immunologic; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholera Toxin; Excitatory Amino Acid Agonists; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Pain; Pertussis Toxin; Spinal Cord; Virulence Factors, Bordetella

2000
Mechanical and thermal hypersensitivity develops following kainate lesion of the ventral posterior lateral thalamus in rats.
    Neuroscience letters, 2000, Aug-18, Volume: 290, Issue:1

    Topics: Afferent Pathways; Animals; Excitatory Amino Acid Agonists; Hot Temperature; Injections, Intraventricular; Kainic Acid; Male; Nociceptors; Pain; Random Allocation; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Ventral Thalamic Nuclei

2000
Intrathecal magnesium sulfate attenuates algogenic behavior and spinal amino acids release after kainic acid receptor activation in rats.
    Neuroscience letters, 2001, Mar-30, Volume: 301, Issue:2

    Topics: Amino Acids; Animals; Aspartic Acid; Behavior, Animal; Calcium Channel Blockers; Excitatory Amino Acid Agonists; Glutamic Acid; Injections, Spinal; Kainic Acid; Magnesium Sulfate; Male; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Taurine

2001
Changes in the levels of nitric oxide synthase and protein kinase C gamma following kainic acid receptor activation in the rat spinal cord.
    Neuroscience letters, 2001, Aug-17, Volume: 309, Issue:1

    Topics: Animals; Behavior, Animal; Cyclooxygenase 1; Cyclooxygenase 2; Excitatory Amino Acid Agonists; Isoenzymes; Kainic Acid; Male; Membrane Proteins; Nitric Oxide; Nitric Oxide Synthase; Nociceptors; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Spinal Cord

2001
The antinociceptive activity of excitatory amino acids in the rat brainstem: an anatomical and pharmacological analysis.
    Brain research, 1992, Jan-13, Volume: 569, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Mapping; Brain Stem; Diencephalon; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Kainic Acid; Male; Medulla Oblongata; Mesencephalon; Microinjections; N-Methylaspartate; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Reticular Formation; Stereotaxic Techniques

1992
Effect of superior colliculus lesions on sensory unit responses in the intralaminar thalamus of the rat.
    Brain research, 1992, Apr-03, Volume: 576, Issue:2

    Topics: Animals; Electric Stimulation; Kainic Acid; Male; Models, Neurological; Motor Activity; Neurons; Pain; Physical Stimulation; Posture; Rats; Stereotaxic Techniques; Superior Colliculi; Thalamus

1992
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
    Neuroscience letters, 1991, Sep-30, Volume: 131, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Capsaicin; Functional Laterality; Hot Temperature; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neuronal Plasticity; Neuropeptides; Pain; Quinoxalines; Rats; Reflex; Time Factors

1991
Interactions between substance P, calcitonin gene-related peptide, taurine and excitatory amino acids in the spinal cord.
    Pain, 1990, Volume: 42, Issue:1

    Topics: Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Interactions; Glutamates; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Pain; Pain Measurement; Quisqualic Acid; Rats; Rats, Inbred Strains; Reaction Time; Self Mutilation; Spinal Cord; Substance P; Taurine

1990
Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model.
    Pain, 1991, Volume: 44, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dose-Response Relationship, Drug; Formaldehyde; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Nociceptors; Pain; Peptide Fragments; Reaction Time; Substance P; Urethane

1991
Neurotoxic effects of excitatory amino acids in the mouse spinal cord: quisqualate and kainate but not N-methyl-D-aspartate induce permanent neural damage.
    Brain research, 1990, Oct-08, Volume: 529, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Aggression; Animals; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; Motor Activity; N-Methylaspartate; Neurons; Neurotoxins; Pain; Paralysis; Quisqualic Acid; Spinal Cord

1990
Is substance P a primary afferent neurotransmitter for nociceptive input? II. Spinalization does not reduce and intrathecal morphine potentiates behavioral responses to substance P.
    Brain research, 1988, Jul-12, Volume: 455, Issue:2

    Topics: Animals; Decerebrate State; Drug Interactions; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P

1988
Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds.
    Brain research, 1988, Jul-12, Volume: 455, Issue:2

    Topics: Afferent Pathways; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P

1988
Is substance P a primary afferent neurotransmitter for nociceptive input? III. Valproic acid and chlordiazepoxide decrease behaviors elicited by intrathecal injection of substance P and excitatory compounds.
    Brain research, 1988, Jul-12, Volume: 455, Issue:2

    Topics: Animals; Anticonvulsants; Chlordiazepoxide; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P; Valproic Acid

1988
Is substance P a primary afferent neurotransmitter for nociceptive input? IV. 2-Amino-5-phosphonovalerate (APV) and [D-Pro2,D-Trp7,9]-substance P exert different effects on behaviors induced by intrathecal substance P, strychnine and kainic acid.
    Brain research, 1988, Jul-12, Volume: 455, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Peptide Fragments; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P; Valine

1988
Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and sigma agonists.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Animals; Aspartic Acid; Enkephalins; Hot Temperature; Kainic Acid; Male; Mice; N-Methylaspartate; Narcotics; Nociceptors; Oxadiazoles; Pain; Phencyclidine; Phentolamine; Quisqualic Acid; Receptors, Opioid; Receptors, sigma; Spinal Cord

1987
The NMDA receptor: central role in pain inhibition in rat periaqueductal gray.
    European journal of pharmacology, 1988, Sep-23, Volume: 154, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesia; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; N-Methylaspartate; Oxadiazoles; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1988
The antinociceptive role of a bulbospinal serotonergic pathway in the rat brain.
    Pain, 1988, Volume: 33, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Analgesia; Animals; Electric Stimulation; Glutamates; Glutamic Acid; Kainic Acid; Male; Medulla Oblongata; Neural Pathways; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Serotonin; Spinal Cord

1988
[Influences of intranigral injection of kainic acid on electroacupuncture analgesia and morphine analgesia in the rabbits].
    Zhen ci yan jiu = Acupuncture research, 1986, Volume: 11, Issue:2

    Topics: Acupuncture Therapy; Animals; Electric Stimulation Therapy; Female; Injections; Kainic Acid; Male; Morphine; Pain; Rabbits; Sensory Thresholds; Substantia Nigra; Transcutaneous Electric Nerve Stimulation

1986