Page last updated: 2024-10-19

inositol and Pain

inositol has been researched along with Pain in 6 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"We tested the ability of lithium (Li(+)) to block heat hyperalgesia, cold allodynia, mechanical allodynia and mechanical hyperalgesia in rats experimentally subjected to painful peripheral neuropathy."7.70Intrathecal lithium reduces neuropathic pain responses in a rat model of peripheral neuropathy. ( Inoue, T; Mashimo, T; Shibata, M; Shimizu, T; Wakisaka, S; Yoshiya, I, 2000)
"We tested the ability of lithium (Li(+)) to block heat hyperalgesia, cold allodynia, mechanical allodynia and mechanical hyperalgesia in rats experimentally subjected to painful peripheral neuropathy."3.70Intrathecal lithium reduces neuropathic pain responses in a rat model of peripheral neuropathy. ( Inoue, T; Mashimo, T; Shibata, M; Shimizu, T; Wakisaka, S; Yoshiya, I, 2000)
"Inositol was also significantly reduced in the spinal stenosis group when age matched to controls."1.31Metabolic changes in the cerebrospinal fluid of patients with lumbar disc herniation or spinal stenosis. ( Gårseth, M; Nygaard, Ø; Rød, M; Sonnewald, U; White, LR; Zwart, JA, 2002)
"Erythromelalgia is a syndrome characterized by erythema, burning pain and increased skin temperature of the affected extremities."1.27Erythromelalgia associated with acute diabetic neuropathy: an unusual condition. ( Bosch, X; Esmatjes, E; Goday, A; Gomis, R; Nubiola, A; Vendrell, J; Vilardell, E, 1988)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fayed, N1
Garcia-Campayo, J1
Magallón, R1
Andrés-Bergareche, H1
Luciano, JV1
Andres, E1
Beltrán, J1
Gutzeit, A1
Meier, D1
Meier, ML1
von Weymarn, C1
Ettlin, DA1
Graf, N1
Froehlich, JM1
Binkert, CA1
Brügger, M1
Gårseth, M1
Sonnewald, U1
White, LR1
Rød, M1
Nygaard, Ø1
Zwart, JA1
Raffa, RB1
Martinez, RP1
Shimizu, T1
Shibata, M1
Wakisaka, S1
Inoue, T1
Mashimo, T1
Yoshiya, I1
Vendrell, J1
Nubiola, A1
Goday, A1
Bosch, X1
Esmatjes, E1
Gomis, R1
Vilardell, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Chronic Pain Brain: Structural White and Gray Matter Correlates of Impaired Muscle Control and Deficient Pain Processing[NCT06143319]80 participants (Actual)Observational2015-10-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for inositol and Pain

ArticleYear
Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate.
    Arthritis research & therapy, 2010, Volume: 12, Issue:4

    Topics: Adult; Aspartic Acid; Brain; Cholic Acid; Cross-Sectional Studies; Diffusion Tensor Imaging; Female;

2010
Insula-specific responses induced by dental pain. A proton magnetic resonance spectroscopy study.
    European radiology, 2011, Volume: 21, Issue:4

    Topics: Adult; Aspartic Acid; Cerebral Cortex; Electrodes; Female; Glutamic Acid; Glutamine; Humans; Inosito

2011
Metabolic changes in the cerebrospinal fluid of patients with lumbar disc herniation or spinal stenosis.
    Journal of neuroscience research, 2002, Sep-01, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Cerebrospinal Fluid; Creatinine; Female; Glucose; Hum

2002
Antinociceptive defect of beige-J mice reversed by i.c.v. IP3 or myo-inositol.
    Neuroreport, 1995, Jul-10, Volume: 6, Issue:10

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Inositol; Inosi

1995
Intrathecal lithium reduces neuropathic pain responses in a rat model of peripheral neuropathy.
    Pain, 2000, Volume: 85, Issue:1-2

    Topics: Animals; Chronic Disease; Cold Temperature; Drug Interactions; Hot Temperature; Hyperalgesia; Inject

2000
Erythromelalgia associated with acute diabetic neuropathy: an unusual condition.
    Diabetes research (Edinburgh, Scotland), 1988, Volume: 7, Issue:3

    Topics: Acute Disease; Adult; Carbamazepine; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Erythromelalg

1988