indazoles has been researched along with Hypoxia in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (14.29) | 18.2507 |
| 2000's | 24 (48.98) | 29.6817 |
| 2010's | 16 (32.65) | 24.3611 |
| 2020's | 2 (4.08) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, Q; Guo, C; Tian, B; Zhang, X; Zhang, Y | 1 |
| Aoki, M; Harada, T; Hirose, K; Ichise, K; Kato, T; Sato, M; Takai, Y; Takeda, K; Wada, Y | 1 |
| Hsieh, KY; Wei, CK; Wu, CC | 1 |
| Kim, KS; Lee, Y; Park, C; Park, J; Rhyu, MR; Shim, MK; Yoon, BK | 1 |
| Waxman, DJ; Zhang, K | 1 |
| Andreeff, M; Benito, J; Ciurea, SO; Jin, L; Kojima, K; Konopleva, M; McQueen, T; Miida, T; Ruvolo, V; Shikami, M; Tabe, Y; Wang, RY | 1 |
| Jiang, C; Li, J; Lian, M; Ma, C; Shen, T; Shi, J; Wang, N; Wei, L; Yu, X; Zhang, C; Zhao, X; Zhu, D | 1 |
| Glover, CJ; Gransbury, GK; Harris, HH; Hughes, JN; Kappen, P; Lay, PA; Levina, A; Musgrave, IF | 1 |
| Brabant, G; Burrows, N; Eustace, A; Fitzmaurice, RJ; Hoang-Vu, C; Irlam, J; Resch, J; Rowling, EJ; Telfer, BA; Valentine, HR; West, CM; Williams, J; Williams, KJ | 1 |
| Fu, W; Gao, X; Hao, X; Ke, X; Ma, N; Wang, W; Wu, J; Zhang, H; Zhang, Z; Zhao, M | 1 |
| Duan, D; Ge, L; Lu, M; Wang, H; Wang, L; Wu, P; Yuan, T; Zhuo, Y | 1 |
| Akai, Y; Haase, VH; Harada, K; Higgins, DF; Iwano, M; Kimura, K; Kubo, A; Nakatani, K; Neilson, EG; Rankin, EB; Saito, Y; Yamaguchi, Y | 1 |
| Cao, W; Du, K; Duan, Y; Hu, Y; Huang, H; Lai, X; Lin, J; Liu, L; Wang, Y; Wu, K; Xiao, H; Yu, Q; Zhang, L | 1 |
| Khan, SA; Luo, W; Nanduri, J; Prabhakar, NR; Semenza, GL; Yuan, G | 1 |
| Huh, JW; Kim, SY; Lee, JH; Lee, YS | 1 |
| Bernhard, EJ; Im, J; McKenna, WG; Muschel, RJ; Qayum, N; Stratford, MR | 1 |
| Avraham, T; Daluvoy, S; Mehrara, BJ; Weitman, ES; Yan, A; Zampell, JC | 1 |
| Al-Mohanna, FA; Deniro, M | 1 |
| Brennan, KR; Clarke, RB; Gregson, HJ; Harrison, H; Landberg, G; Rogerson, L | 1 |
| Hada, J; Hayashi, Y; Jiang, MH; Kaku, T | 1 |
| Burk, M; Harris, MB; Lukowiak, K; Remmers, JE; Smyth, K; Taylor, BE | 1 |
| Brogan, TV; Deem, S; Kerr, ME; Luchtel, DL; Swenson, ER; Vaughan, DJ | 1 |
| Dick, TE; Han, F; Price, ER; Strohl, KP | 1 |
| Aschner, JL; Fike, CD; Kaplowitz, MR; Zhang, Y | 1 |
| Fritz, KI; Haider, SH; Mishra, OP; Papadopoulos, MD; Parikh, N; Sorrentino, DF | 1 |
| Chun, YS; Park, JW; Yeo, EJ | 1 |
| Delivoria-Papadopoulos, M; Mishra, OP | 1 |
| Andreasson, KA; Li, H; McCullough, LD; Pin, S; Wang, MM; Zeng, Z | 1 |
| Funasaka, T; Hogan, V; Raz, A; Yanagawa, T | 1 |
| Budzińska, K; Kolesnikova, E; Marczak, M; Pokorski, M | 1 |
| Delivoria-Papadopoulos, M; Fritz, KI; Katsetos, CD; Legido, A; Mishra, OP; Parikh, NA | 1 |
| Albert, DH; Fesik, SW; Li, L; Lin, X; Shen, Y; Shoemaker, AR | 1 |
| Encinas, JM; Fernández, AP; Martínez, A; Rodrigo, J; Serrano, J | 1 |
| D'Alecy, LG; Song, MY; Whitesall, SE; Zwemer, CF | 1 |
| Ashraf, QM; Delivoria-Papadopoulos, M; Mishra, OP; Zubrow, AB | 1 |
| Harwood, FC; Houghton, PJ; Kurmasheva, RT | 1 |
| Bancalari, E; Ladino, J; Suguihara, C | 1 |
| Converso, DP; Fiszer de Plazas, S; Giusti, S; Poderoso, JJ | 1 |
| Falk, A; Larsson, A; Risberg, B; Schützer, KM | 1 |
| Armstead, WM; Wilderman, MJ | 1 |
| Hsu, KS; Huang, CC | 1 |
| Hudetz, AG; Kampine, JP; Shen, H | 1 |
| Gidday, JM; Holtzman, DM; Maceren, RG; Park, TS; Pelligrino, DA; Shah, AR; Wang, Q | 1 |
| Beal, MF; Chan, PH; Chang, LH; Espanol, MT; Gregory, GA; Hasegawa, K; James, TL; Litt, L | 1 |
| Gautier, H; Murariu, C | 1 |
| Branco, LG; Carnio, EC; Steiner, AA | 1 |
| Hara, A; Ito, Z; Kusakari, J; Tabuchi, K; Takahashi, K; Wada, T | 1 |
| Gozal, D; Torres, JE | 1 |
| Kline, DD; Overholt, JL; Prabhakar, NR | 1 |
1 review(s) available for indazoles and Hypoxia
| Article | Year |
|---|---|
New anticancer strategies targeting HIF-1.
Topics: Adaptation, Physiological; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Targeting; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Neoplasms; Nuclear Proteins; Transcription Factors | 2004 |
48 other study(ies) available for indazoles and Hypoxia
| Article | Year |
|---|---|
Hypoxia-Inducible Factor 1α Stability Modified by Glutaredoxin-1 in Necrotizing Enterocolitis.
Topics: Animals; Enterocolitis, Necrotizing; Glutaredoxins; Glutathione; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Mice; Mice, Inbred C57BL; Microcirculation; Vascular Endothelial Growth Factor A | 2022 |
YC-1 sensitizes the antitumor effects of boron neutron capture therapy in hypoxic tumor cells.
Topics: Antineoplastic Agents; Boron Neutron Capture Therapy; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Deferoxamine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Large Neutral Amino Acid-Transporter 1; MCF-7 Cells; Neoplasms; Neutrons; Oxygen; Phenylalanine; Radiation-Sensitizing Agents; RNA, Small Interfering | 2020 |
YC-1 Prevents Tumor-Associated Tissue Factor Expression and Procoagulant Activity in Hypoxic Conditions by Inhibiting p38/NF-κB Signaling Pathway.
Topics: Blood Coagulation; Blood Platelets; Cell Line, Tumor; Cyclic Nucleotide-Regulated Protein Kinases; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Thromboplastin | 2019 |
Indazole-Cl inhibits hypoxia-induced cyclooxygenase-2 expression in vascular smooth muscle cells.
Topics: Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Estrogen Receptor beta; Flow Cytometry; Hypoxia; Indazoles; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Sequence Analysis, RNA | 2019 |
Impact of tumor vascularity on responsiveness to antiangiogenesis in a prostate cancer stem cell-derived tumor model.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Axitinib; Cell Line, Tumor; Disease Models, Animal; Humans; Hypoxia; Imidazoles; Indazoles; Male; Neoplastic Stem Cells; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Prostatic Neoplasms; Protein Kinase Inhibitors; Sorafenib; Xenograft Model Antitumor Assays | 2013 |
PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment.
Topics: Apoptosis; Biphenyl Compounds; Bone Marrow; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Drug Synergism; Gene Expression Regulation, Leukemic; Humans; Hypoxia; Indazoles; Leukemia, Myeloid, Acute; Mesenchymal Stem Cells; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Phosphoinositide-3 Kinase Inhibitors; Piperazines; RNA Interference; Sulfonamides; Tumor Microenvironment | 2013 |
15-Lipoxygenase and 15-hydroxyeicosatetraenoic acid regulate intravascular thrombosis in pulmonary hypertension.
Topics: Animals; Arachidonate 15-Lipoxygenase; Blood Platelets; Cells, Cultured; Chemokine CCL2; Cytokines; Humans; Hydroxyeicosatetraenoic Acids; Hypertension, Pulmonary; Hypoxia; Indazoles; Lipoxygenase Inhibitors; Male; Masoprocol; Platelet Activation; Propionates; Pulmonary Artery; Random Allocation; Rats; Rats, Wistar; RNA Interference; RNA, Small Interfering; Signal Transduction; Thrombosis; Vascular Resistance | 2015 |
Comparison of KP1019 and NAMI-A in tumour-mimetic environments.
Topics: Antineoplastic Agents; Dimethyl Sulfoxide; Humans; Hypoxia; Indazoles; Neuroblastoma; Organometallic Compounds; Ruthenium; Ruthenium Compounds; Spheroids, Cellular; Tumor Cells, Cultured; Tumor Microenvironment; X-Ray Absorption Spectroscopy | 2016 |
Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas.
Topics: Animals; Carcinoma; Carcinoma, Papillary; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Enzyme Activation; Female; Histones; Humans; Hypoxia; Indazoles; Mice; Mice, Nude; Neoplasm Transplantation; Oxygen; Phosphatidylinositol 3-Kinases; Radiation Tolerance; Signal Transduction; Sulfonamides; Thyroid Cancer, Papillary; Thyroid Neoplasms | 2016 |
Inhibition of Hypoxia-Induced Retinal Angiogenesis by Specnuezhenide, an Effective Constituent of Ligustrum lucidum Ait., through Suppression of the HIF-1α/VEGF Signaling Pathway.
Topics: Angiogenesis Inhibitors; Animals; Cell Hypoxia; Cell Line; Cobalt; Diabetic Retinopathy; Disease Models, Animal; Epithelial Cells; Gene Expression Regulation; Glucosides; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Indazoles; Ligustrum; Plant Extracts; Pyrans; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinal Pigment Epithelium; Signal Transduction; Vascular Endothelial Growth Factor A | 2016 |
[Hypoxic condition promotes olfactory mucosa mesenchymal stem cells to differentiate into neurons and
underlying mechanisms].
Topics: Blotting, Western; Cell Differentiation; Cells, Cultured; Culture Media, Conditioned; Flow Cytometry; Glial Fibrillary Acidic Protein; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Mesenchymal Stem Cells; Neurogenesis; Neuroglia; Neurons; Olfactory Mucosa; Potassium Channels; Signal Transduction; Tubulin | 2016 |
Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis.
Topics: Aging; Animals; Disease Models, Animal; Enzyme Activators; Epithelial Cells; Female; Fibrosis; Gene Deletion; Gene Expression; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Transfection; Up-Regulation; Von Hippel-Lindau Tumor Suppressor Protein | 2008 |
Hypoxia-inducible factor-1α is essential for hypoxia-induced mesenchymal stem cell mobilization into the peripheral blood.
Topics: Animals; Blood Cells; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Movement; Cells, Cultured; Chemokine CXCL12; Colony-Forming Units Assay; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunophenotyping; Indazoles; Male; Mesenchymal Stem Cells; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2011 |
Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia.
Topics: Animals; Carotid Body; Central Nervous System; Deferoxamine; Digoxin; Enzyme Inhibitors; Fibroblasts; Furans; Gene Expression Regulation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NADPH Oxidase 2; NADPH Oxidases; PC12 Cells; Peripheral Nervous System; Rats; Reactive Oxygen Species; Siderophores; Sleep Apnea Syndromes | 2011 |
YC-1 attenuates hypoxia-induced pulmonary arterial hypertension in mice.
Topics: Animals; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Endothelin-1; Enzyme Activators; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Hypoxia; Indazoles; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Pulmonary Artery; Tumor Suppressor Protein p53 | 2011 |
Modulation of the tumor microvasculature by phosphoinositide-3 kinase inhibition increases doxorubicin delivery in vivo.
Topics: Animals; Doxorubicin; Drug Delivery Systems; Female; Humans; Hypoxia; Immunoenzyme Techniques; Indazoles; Mammary Neoplasms, Animal; Mice; Mice, Nude; Mice, Transgenic; Microvessels; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Sulfonamides | 2012 |
HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation.
Topics: Animals; Blotting, Western; CD4 Antigens; Cell Hypoxia; Edema; Female; Gene Expression; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Indazoles; Inflammation; Lymph; Lymphangiogenesis; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor C; Wound Healing | 2012 |
Zinc transporter 8 (ZnT8) expression is reduced by ischemic insults: a potential therapeutic target to prevent ischemic retinopathy.
Topics: Animals; Cation Transport Proteins; Cell Line; Enzyme Activators; Gene Expression Regulation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Image Processing, Computer-Assisted; Immunohistochemistry; Indazoles; Ischemia; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Rats; Retina; Retinal Diseases; Zinc Transporter 8 | 2012 |
Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ER-α status.
Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Estrogen Antagonists; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Nude; Neoplastic Stem Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Tamoxifen; Transplantation, Heterologous | 2013 |
Different effects of eNOS and nNOS inhibition on transient forebrain ischemia.
Topics: Action Potentials; Animals; Blood Pressure; Electrophysiology; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Hypoxia; Indazoles; Ischemic Attack, Transient; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Ornithine; Prosencephalon; Rats; Rats, Wistar; Regional Blood Flow | 2002 |
Nitric oxide mediates metabolism as well as respiratory and cardiac responses to hypoxia in the snail lymnaea stagnalis.
Topics: Animals; Arginine; Heart Rate; Hypoxia; Indazoles; Lymnaea; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Respiration; Time Factors | 2003 |
Contributions of nitric oxide synthase isozymes to exhaled nitric oxide and hypoxic pulmonary vasoconstriction in rabbit lungs.
Topics: Acetylcholine; Amidines; Animals; Benzylamines; Breath Tests; Hypoxia; Immunohistochemistry; Indazoles; Lung; Nebulizers and Vaporizers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxygen; Pulmonary Circulation; Pulmonary Wedge Pressure; Rabbits; Specific Pathogen-Free Organisms; Vasoconstriction; Vasodilator Agents | 2003 |
7-nitroindazole and posthypoxic ventilatory behavior in the A/J and C57BL/6J mouse strains.
Topics: Animals; Apnea; Carbon Dioxide; Enzyme Inhibitors; Hypercapnia; Hypoxia; Indazoles; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Plethysmography, Whole Body; Respiratory Mechanics | 2003 |
Impaired NO signaling in small pulmonary arteries of chronically hypoxic newborn piglets.
Topics: Animals; Animals, Newborn; Caveolin 1; Caveolins; Chronic Disease; Enzyme Inhibitors; Guanidines; HSP90 Heat-Shock Proteins; Hypoxia; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Artery; Signal Transduction; Swine | 2004 |
Nitric oxide-mediated modification of the glycine binding site of the NMDA receptor during hypoxia in the cerebral cortex of the newborn piglet.
Topics: Animals; Animals, Newborn; Binding Sites; Cerebral Cortex; Enzyme Inhibitors; Glycine; Hypoxia; Indazoles; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Swine | 2004 |
Effect of hypoxia on the expression and activity of mitogen-activated protein (MAP) kinase-phosphatase-1 (MKP-1) and MKP-3 in neuronal nuclei of newborn piglets: the role of nitric oxide.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Blotting, Western; Cell Cycle Proteins; Cell Nucleus; Cerebral Cortex; Dual Specificity Phosphatase 1; Gene Expression Regulation, Developmental; Hypoxia; Immediate-Early Proteins; Immunoprecipitation; Indazoles; Mitogen-Activated Protein Kinase 3; Neurons; Nitric Oxide; Phosphocreatine; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Swine | 2004 |
Sex differences in cell death.
Topics: Animals; Animals, Newborn; Cell Death; Disease Models, Animal; DNA-Binding Proteins; Drug Interactions; Female; Genotype; Glucose; High Mobility Group Proteins; Hippocampus; Hypoxia; Indazoles; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Nitric Oxide; Organ Culture Techniques; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Characteristics; SOXB1 Transcription Factors; Stroke; Superoxide Dismutase; Time Factors; Transcription Factors | 2005 |
Regulation of phosphoglucose isomerase/autocrine motility factor expression by hypoxia.
Topics: Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplastic; Glucose-6-Phosphate Isomerase; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Phosphatidylinositol 3-Kinases; Signal Transduction; Vascular Endothelial Growth Factor A | 2005 |
Neurotransmitter mechanisms in the enhancement of the hypoxic ventilatory response by antecedent hyperoxia in the anesthetized rat.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Dose-Response Relationship, Drug; Electromagnetic Fields; Electromyography; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Hyperoxia; Hypoxia; Indazoles; Male; Nerve Tissue Proteins; Neurotransmitter Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pharmaceutical Vehicles; Rats; Respiratory Mechanics | 2005 |
Effect of 7-nitroindazole sodium on the cellular distribution of neuronal nitric oxide synthase in the cerebral cortex of hypoxic newborn piglets.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Hypoxia; Immunohistochemistry; Indazoles; Nitric Oxide Synthase Type I; Swine | 2006 |
Hypoxia-inducible factor-1 inhibition in combination with temozolomide treatment exhibits robust antitumor efficacy in vivo.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Aryl Hydrocarbon Receptor Nuclear Translocator; Caspases; Cell Death; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Humans; Hypoxia; Indazoles; Mice; Mice, SCID; Phenylurea Compounds; Structure-Activity Relationship; Temozolomide; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2006 |
Effects of acute hypobaric hypoxia on the nitric oxide system of the rat cerebral cortex: Protective role of nitric oxide inhibitors.
Topics: Altitude; Analysis of Variance; Animals; Blotting, Western; Calcium; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Hypoxia; Immunohistochemistry; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Time Factors; Tyrosine | 2006 |
Acute and conditioned hypoxic tolerance augmented by endothelial nitric oxide synthase inhibition in mice.
Topics: Acute Disease; Animals; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Hypoxia; Imines; Indazoles; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Time Factors | 2007 |
Nuclear Ca(++)-influx, Ca (++)/calmodulin-dependent protein kinase IV activity and CREB protein phosphorylation during post-hypoxic reoxygenation in neuronal nuclei of newborn piglets: the role of nitric oxide.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Blotting, Western; Calcium; Calcium Radioisotopes; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Hypoxia; Immunoprecipitation; Indazoles; Neurons; Neuroprotective Agents; Nitric Oxide; Phosphocreatine; Phosphorylation; Swine | 2006 |
Differential regulation of vascular endothelial growth factor by Akt and mammalian target of rapamycin inhibitors in cell lines derived from childhood solid tumors.
Topics: Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypoxia; Indazoles; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxygen; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A | 2007 |
Ventilatory response to hypoxia during endotoxemia in young rats: role of nitric oxide.
Topics: Animals; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Female; Hypoxia; Indazoles; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxygen Consumption; Pulmonary Ventilation; Rats; Rats, Wistar; Time Factors | 2007 |
Hypoxia induces complex I inhibition and ultrastructural damage by increasing mitochondrial nitric oxide in developing CNS.
Topics: Animals; Central Nervous System; Chick Embryo; Dose-Response Relationship, Drug; Electron Transport Complex I; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Hypoxia; Indazoles; Microscopy, Electron, Transmission; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Time Factors | 2008 |
Leukotriene receptor antagonism prevents lung protein leakage and hypoxaemia in a septic cat model.
Topics: Analysis of Variance; Animals; Capillary Permeability; Cats; Diethylcarbamazine; Disease Models, Animal; Hypoxia; Indazoles; Leukotriene Antagonists; Leukotrienes; Lung; Organ Size; Shock, Septic | 1994 |
Role of neuronal NO synthase in relationship between NO and opioids in hypoxia-induced pial artery dilation.
Topics: Animals; Cerebral Arteries; Cyclic GMP; Endorphins; Enkephalins; Enzyme Inhibitors; Female; Hypoxia; Indazoles; Male; Neurons; Nitric Oxide; Nitric Oxide Synthase; Pia Mater; Swine; Tetrodotoxin; Vasodilation | 1997 |
Nitric oxide signalling is required for the generation of anoxia-induced long-term potentiation in the hippocampus.
Topics: Animals; Arginine; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Indazoles; Long-Term Potentiation; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Reaction Time; Signal Transduction; Synaptic Transmission | 1997 |
Nitric oxide from neuronal NOS plays critical role in cerebral capillary flow response to hypoxia.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Capillaries; Carbon Dioxide; Cerebrovascular Circulation; Enzyme Inhibitors; Hemoglobins; Hydrogen-Ion Concentration; Hypoxia; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Rats; Rats, Sprague-Dawley; Video Recording | 1998 |
Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning.
Topics: Animals; Animals, Newborn; Brain Ischemia; Calcium; Dizocilpine Maleate; Enzyme Inhibitors; Guanidines; Hypoxia; Indazoles; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Oxygen; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
NOS inhibitors decrease hypoxia-induced ATP reductions in respiring cerebrocortical slices.
Topics: Adenosine Triphosphate; Animals; Cerebral Cortex; Enzyme Inhibitors; Hypoxia; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley | 1999 |
Role of nitric oxide in hypoxic hypometabolism in rats.
Topics: Animals; Body Temperature Regulation; Enzyme Inhibitors; Hypoxia; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Respiration | 1999 |
Role of neuronal nitric oxide synthase in hypoxia-induced anapyrexia in rats.
Topics: Animals; Blood Pressure; Body Temperature; Enzyme Inhibitors; Heart Rate; Hypoxia; Indazoles; Injections, Intraperitoneal; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar | 2000 |
Effect of 7-nitroindazole upon cochlear dysfunction induced by transient local anoxia.
Topics: Action Potentials; Animals; Cochlea; Differential Threshold; Enzyme Inhibitors; Guinea Pigs; Hypoxia; Indazoles; Ischemia; Reperfusion Injury; Time Factors | 2000 |
Brainstem nitric oxide tissue levels correlate with anoxia-induced gasping activity in the developing rat.
Topics: Aging; Animals; Animals, Newborn; Brain Stem; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hypoxia; Indazoles; Neocortex; Nitric Oxide; Nitric Oxide Synthase; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Respiration; Respiration Disorders | 2001 |
Mutant mice deficient in NOS-1 exhibit attenuated long-term facilitation and short-term potentiation in breathing.
Topics: Animals; Carbon Dioxide; Enzyme Inhibitors; Female; Hypoxia; Indazoles; Male; Mice; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Reference Values; Respiration | 2002 |