Page last updated: 2024-10-28

ifosfamide and Edema

ifosfamide has been researched along with Edema in 7 studies

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"Ifosfamide (IFS) is an antineoplastic alkylating agent whose major side effect is hemorrhagic cystitis (HC)."7.74Amifostine and glutathione prevent ifosfamide- and acrolein-induced hemorrhagic cystitis. ( Batista, CK; Brito, GA; Cunha, FQ; Leitão, BT; Mota, JM; Ribeiro, RA; Souza, MH; Souza, ML, 2007)
" Groups (N = 6-8) were submitted to right or left paw edema (PE) with carrageenan (100 microg) or Dextran (200 microg), hemorrhagic cystitis with ifosfamide (200 mg/kg, ip) or gastric injury (GI) with indomethacin (20 mg/kg, vo)."3.75Hind limb ischemic preconditioning induces an anti-inflammatory response by remote organs in rats. ( Gomes, AS; Loiola, RT; Ribeiro, RA; Rocha, EL; Simão, AF; Souza Filho, MV; Souza, MH, 2009)
"Ifosfamide (IFS) is an antineoplastic alkylating agent whose major side effect is hemorrhagic cystitis (HC)."3.74Amifostine and glutathione prevent ifosfamide- and acrolein-induced hemorrhagic cystitis. ( Batista, CK; Brito, GA; Cunha, FQ; Leitão, BT; Mota, JM; Ribeiro, RA; Souza, MH; Souza, ML, 2007)
"More recently, a number of cases of panniculitis and subcutaneous inflammatory oedema have been described."1.37[Severe skin reaction with mucous membrane inflammation during MINE chemotherapy]. ( Camus, M; Guillet, G; Hainaut-Wierzbicka, E; Levillain, P; Lopez, L; Saulnier, JP, 2011)
" Ifosfamide, although itself the effective antineoplastic drug useful in situations which have proved refractory to cyclophosphamide therapy, has the side-effect toxicities caused by its metabolities that pose clinically a very real problem."1.30Influence of mesna on urotoxic effects of selected bromosubstituted analogs of ifosfamide. ( Konarski, L; Kowalski, P; Kuśnierczyk, H; Radzikowski, C, 1997)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Souza Filho, MV1
Loiola, RT1
Rocha, EL1
Simão, AF1
Gomes, AS1
Souza, MH2
Ribeiro, RA3
Camus, M1
Hainaut-Wierzbicka, E1
Levillain, P1
Saulnier, JP1
Lopez, L1
Guillet, G1
Wang, PL1
Cheng, YB1
Kuerban, G1
Batista, CK1
Mota, JM1
Souza, ML1
Leitão, BT1
Brito, GA1
Cunha, FQ1
Lima, MV1
Ferreira, FV1
Macedo, FY1
de Castro Brito, GA1
Kuśnierczyk, H1
Konarski, L1
Kowalski, P1
Radzikowski, C1
Maubec, E1
Oberlin, O1
Belhadj, K1
Roujeau, JC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Remote Ischemic Preconditioning on Restenosis Post Lower Limb Revascularization Angioplasty: A Pilot Randomized Control Trial[NCT02406131]40 participants (Anticipated)Interventional2018-04-30Suspended (stopped due to logistic issues - no available scans for participants at the moment need to postponed starting dates)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ifosfamide and Edema

ArticleYear
Histological changes in bladders of patients submitted to ifosfamide chemotherapy even with mesna prophylaxis.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Cysto

2007

Other Studies

6 other studies available for ifosfamide and Edema

ArticleYear
Hind limb ischemic preconditioning induces an anti-inflammatory response by remote organs in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2009, Volume: 42, Issue:10

    Topics: Acute Disease; Animals; Carrageenan; Cystitis; Edema; Hindlimb; Ifosfamide; Indomethacin; Inflammati

2009
[Severe skin reaction with mucous membrane inflammation during MINE chemotherapy].
    Annales de dermatologie et de venereologie, 2011, Volume: 138, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Drug Eruptions; Edema; Etoposide; Female

2011
The clinical characteristic differences between thrombosis-related edema and lymphedema following radiotherapy or chemoradiotherapy for patients with cervical cancer.
    Journal of radiation research, 2012, Volume: 53, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy

2012
Amifostine and glutathione prevent ifosfamide- and acrolein-induced hemorrhagic cystitis.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:1

    Topics: Acrolein; Amifostine; Animals; Antidotes; Antineoplastic Agents, Alkylating; Cystitis; Dose-Response

2007
Influence of mesna on urotoxic effects of selected bromosubstituted analogs of ifosfamide.
    Archivum immunologiae et therapiae experimentalis, 1997, Volume: 45, Issue:1

    Topics: Administration, Oral; Animals; Cystitis; Edema; Female; Hemorrhage; Ifosfamide; Injections, Intraper

1997
[Subcutaneous inflammatory edema induced by MINE chemotherapy].
    Annales de dermatologie et de venereologie, 2001, Volume: 128, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Capillary Leak Syndrome; Creatin

2001