ibotenic acid has been researched along with Ache in 16 studies
Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bilateral lesions of the RMM with ibotenic acid, a soma-selective neurotoxin, were performed to study their effects on the spontaneous pain-related behaviors and hyperalgesia, which were determined by counting the number of flinching reflex per 5 min (1 h) and by measuring paw withdrawal thermal latency (PWTL) and mechanical threshold (PWMT) to radiant heat and von-Frey filaments to both hind paws in conscious rats, respectively." | 3.72 | Supraspinal contribution to development of both tonic nociception and referred mirror hyperalgesia: a comparative study between formalin test and bee venom test in the rat. ( Chen, HS; Chen, J; Li, MM; Shi, J, 2003) |
| "Pain is a multidimensional conscious experience including sensory and negative affective components." | 1.32 | Differential contributions of the basolateral and central nuclei of the amygdala in the negative affective component of chemical somatic and visceral pains in rats. ( Minami, M; Nakagawa, T; Satoh, M; Tanimoto, S; Yamauchi, Y, 2003) |
| "Since there is often an expansion of hyperalgesia to tissue adjacent, and even distant from the site of injury (secondary hyperalgesia), it is thought that this phenomenon primarily involves mechanisms of central modulation/plasticity." | 1.30 | Descending facilitatory influences from the rostral medial medulla mediate secondary, but not primary hyperalgesia in the rat. ( Gebhart, GF; Urban, MO; Zahn, PK, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 9 (56.25) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikeda, H | 1 |
| Takasu, S | 1 |
| Murase, K | 1 |
| Imbe, H | 1 |
| Okamoto, K | 1 |
| Donishi, T | 1 |
| Senba, E | 1 |
| Kimura, A | 1 |
| Chen, HS | 1 |
| Li, MM | 1 |
| Shi, J | 1 |
| Chen, J | 1 |
| Tanimoto, S | 1 |
| Nakagawa, T | 1 |
| Yamauchi, Y | 1 |
| Minami, M | 1 |
| Satoh, M | 1 |
| Al Amin, HA | 1 |
| Atweh, SF | 1 |
| Jabbur, SJ | 1 |
| Saadé, NE | 1 |
| Neugebauer, V | 1 |
| Lücke, T | 1 |
| Schaible, HG | 1 |
| Meller, ST | 1 |
| Dykstra, CL | 1 |
| Gebhart, GF | 4 |
| Urban, MO | 1 |
| Zahn, PK | 1 |
| Tsai, C | 1 |
| Randich, A | 2 |
| Thurston, CL | 1 |
| Ludwig, PS | 1 |
| Robertson, JD | 1 |
| Rasmussen, C | 1 |
| Matsumoto, RR | 1 |
| Walker, JM | 1 |
| Coderre, TJ | 1 |
| Melzack, R | 1 |
| Bouhassira, D | 1 |
| Bing, Z | 1 |
| Le Bars, D | 1 |
| Ren, K | 1 |
| Wall, PD | 1 |
| Bery, J | 1 |
| Saadé, N | 1 |
| Aimone, LD | 1 |
| Bauer, CA | 1 |
16 other studies available for ibotenic acid and Ache
| Article | Year |
|---|---|
Contribution of anterior cingulate cortex and descending pain inhibitory system to analgesic effect of lemon odor in mice.
Topics: Administration, Inhalation; Affect; Animals; Aromatherapy; Benzazepines; Disease Models, Animal; Dop | 2014 |
Involvement of descending facilitation from the rostral ventromedial medulla in the enhancement of formalin-evoked nocifensive behavior following repeated forced swim stress.
Topics: Animals; Avoidance Learning; Behavior, Animal; Foot; Formaldehyde; Ibotenic Acid; Male; Medulla Oblo | 2010 |
Supraspinal contribution to development of both tonic nociception and referred mirror hyperalgesia: a comparative study between formalin test and bee venom test in the rat.
Topics: Animals; Bee Venoms; Brain; Formaldehyde; Functional Laterality; Hindlimb; Hyperalgesia; Ibotenic Ac | 2003 |
Differential contributions of the basolateral and central nuclei of the amygdala in the negative affective component of chemical somatic and visceral pains in rats.
Topics: Acetic Acid; Affect; Amygdala; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Psycholo | 2003 |
Effects of ventral hippocampal lesion on thermal and mechanical nociception in neonates and adult rats.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Brain Diseases; Female; Hippocampus; Hot T | 2004 |
Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on the responses of rat spinal neurons with joint input.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4- | 1993 |
Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Hot Temperature; Ib | 1993 |
Descending facilitatory influences from the rostral medial medulla mediate secondary, but not primary hyperalgesia in the rat.
Topics: Animals; Carrageenan; Functional Laterality; Hindlimb; Hot Temperature; Hyperalgesia; Ibotenic Acid; | 1999 |
The caudal subnucleus caudalis (medullary dorsal horn) acts as an interneuronal relay site in craniofacial nociceptive reflex activity.
Topics: Animals; Electromyography; Excitatory Amino Acid Agonists; Face; Ibotenic Acid; Interneurons; Male; | 1999 |
Intravenous morphine-induced activation of vagal afferents: peripheral, spinal, and CNS substrates mediating inhibition of spinal nociception and cardiovascular responses.
Topics: Afferent Pathways; Animals; Blood Pressure; Brain; Heart Rate; Ibotenic Acid; Lidocaine; Male; Medul | 1992 |
Inhibition of rubral neurons by noxious and non-noxious pressure.
Topics: Animals; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hindlimb; Ibotenic A | 1991 |
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4- | 1991 |
Studies of the brain structures involved in diffuse noxious inhibitory controls: the mesencephalon.
Topics: Anesthesia; Animals; Electrophysiology; Ibotenic Acid; Male; Mesencephalon; Nerve Fibers; Pain; Peri | 1990 |
Electrical stimulation of cervical vagal afferents. II. Central relays for behavioral antinociception and arterial blood pressure decreases.
Topics: Animals; Behavior, Animal; Blood Pressure; Brain Stem; Electric Stimulation; Ibotenic Acid; Lidocain | 1990 |
Effects of lesions to rat spinal cord lamina I cell projection pathways on reactions to acute and chronic noxious stimuli.
Topics: Animals; Brain Mapping; Cerebral Cortex; Ibotenic Acid; Male; Neural Pathways; Nociceptors; Pain; Pe | 1988 |
Brain-stem relays mediating stimulation-produced antinociception from the lateral hypothalamus in the rat.
Topics: Animals; Brain; Brain Stem; Hot Temperature; Hypothalamus; Ibotenic Acid; Injections; Lidocaine; Mal | 1988 |