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hydroxyindoleacetic acid and Chemical Dependence

hydroxyindoleacetic acid has been researched along with Chemical Dependence in 32 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Research Excerpts

ExcerptRelevanceReference
"Exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) produces a syndrome that resembles Parkinson's disease."7.67The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). ( Burns, RS; Ebert, MH; Kopin, IJ; LeWitt, PA; Pakkenberg, H, 1985)
" For example, hypothesized serotonergic deficits in alcoholism, endorphin deficits in opioid dependence, and dopamine depletion in cocaine dependence all might predispose to depression."4.78Hypothesized neurochemical models for psychiatric syndromes in alcohol and drug dependence. ( Extein, IL; Gold, MS, 1993)
"Exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) produces a syndrome that resembles Parkinson's disease."3.67The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). ( Burns, RS; Ebert, MH; Kopin, IJ; LeWitt, PA; Pakkenberg, H, 1985)
" Taken together, our data indicate that chronic use of stanozolol significantly affects brain monoamines leading to neurochemical modifications possibly involved in depression and stress-related states."1.38Neurochemical consequence of steroid abuse: stanozolol-induced monoaminergic changes. ( Colaianna, M; Cuomo, V; Morgese, MG; Schiavone, S; Trabace, L; Tucci, P; Zotti, M, 2012)
"We have demonstrated that chronic administration of neuropeptide FF (NPFF) into the lateral ventricle potentiated the behavioral sensitization to amphetamine."1.30Neuropeptide FF potentiates the behavioral sensitization to amphetamine and alters the levels of neurotransmitters in the medial prefrontal cortex. ( Chen, JC; Huang, YK; Li, JY; Liang, KW, 1999)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199016 (50.00)18.7374
1990's5 (15.63)18.2507
2000's6 (18.75)29.6817
2010's5 (15.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krasnova, IN1
Chiflikyan, M1
Justinova, Z1
McCoy, MT1
Ladenheim, B1
Jayanthi, S1
Quintero, C1
Brannock, C1
Barnes, C1
Adair, JE1
Lehrmann, E1
Kobeissy, FH1
Gold, MS2
Becker, KG1
Goldberg, SR1
Cadet, JL1
Chen, C1
Kostakis, C1
Gerber, JP1
Tscharke, BJ1
Irvine, RJ1
White, JM1
Asellus, P1
Nordström, P1
Jokinen, J1
Tucci, P1
Morgese, MG1
Colaianna, M1
Zotti, M1
Schiavone, S1
Cuomo, V1
Trabace, L1
Okamoto, R1
Itoh, Y1
Murata, Y1
Kobayashi, D1
Hosoi, M1
Mine, K1
Soderstrom, H1
Blennow, K1
Sjodin, AK1
Forsman, A1
Morley, KC1
Cornish, JL1
Li, KM1
McGregor, IS1
Gilligan, J1
Lee, B1
Gardner, EL1
Liu, X1
Paredes, W1
Giordano, A1
Spector, J1
Lepore, M1
Wu, KM1
Froimowitz, M1
Cramer, H1
Ohlmeier, D1
Nabeshima, T1
Ho, IK1
Tagashira, E1
Hiramori, T1
Urano, T1
Yanaura, S1
Extein, IL1
Chen, JC1
Li, JY1
Liang, KW1
Huang, YK1
Kish, SJ1
Furukawa, Y1
Ang, L1
Vorce, SP1
Kalasinsky, KS1
Mayerhofer, A1
Kovar, KA1
Schmidt, WJ1
Morgan, WW1
Grant, RW1
See, RE1
Adams-Curtis, L1
Chapman, MA1
Ricaurte, GA1
Finnegan, KT1
Irwin, I1
Langston, JW1
Piazza, PV1
Rougé-Pont, F1
Deminière, JM1
Kharoubi, M1
Le Moal, M1
Simon, H1
Roy, A1
Degrell, I1
Pék, G1
Nagy, D1
Nagy, E1
Hoyer, S1
Stapleton, JM1
Eckardt, MJ1
Martin, P1
Adinoff, B1
Roehrich, L1
Bone, G1
Rubinow, D1
Linnoila, M1
Burns, RS1
LeWitt, PA1
Ebert, MH1
Pakkenberg, H1
Kopin, IJ1
Post, RM1
Goodwin, FK1
Chernik, DA1
Ramsey, TA1
Mendels, J1
Ahtee, L1
Eriksson, K1
Turnbull, MJ2
Ballinger, BR1
Bowers, MB2
Kleber, HD1
Davis, L1
Angrist, B1
Shopsin, B1
Gershon, S1
Wilk, S1
Kelvin, AS1

Reviews

3 reviews available for hydroxyindoleacetic acid and Chemical Dependence

ArticleYear
The psychopharmacologic treatment of violent youth.
    Annals of the New York Academy of Sciences, 2004, Volume: 1036

    Topics: Adolescent; Antipsychotic Agents; Child; Humans; Hydroxyindoleacetic Acid; Hyperthyroidism; Mental D

2004
Hypothesized neurochemical models for psychiatric syndromes in alcohol and drug dependence.
    Journal of addictive diseases, 1993, Volume: 12, Issue:3

    Topics: Alcoholism; Brain Diseases; Cocaine; Comorbidity; Diagnosis, Dual (Psychiatry); Dopamine; Dopamine A

1993
Suicide and psychiatric patients.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Alcoholism; Blood Platelets; Emergency Services, Psychiatric;

1985

Trials

2 trials available for hydroxyindoleacetic acid and Chemical Dependence

ArticleYear
Treatment of alcoholic organic brain syndrome with the serotonin reuptake inhibitor fluvoxamine: a preliminary study.
    Advances in alcohol & substance abuse, 1988, Volume: 7, Issue:3-4

    Topics: Aged; Alcohol Amnestic Disorder; Dementia; Double-Blind Method; Ethanol; Fluvoxamine; Humans; Hydrox

1988
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
    Psychotherapy and psychosomatics, 1974, Volume: 23, Issue:1-6

    Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans;

1974

Other Studies

27 other studies available for hydroxyindoleacetic acid and Chemical Dependence

ArticleYear
CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat.
    Neurobiology of disease, 2013, Volume: 58

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Central Nervous System Stimulants; Conditioning, Operant; C

2013
Towards finding a population biomarker for wastewater epidemiology studies.
    The Science of the total environment, 2014, Jul-15, Volume: 487

    Topics: Biomarkers; Cotinine; Hydroxyindoleacetic Acid; Illicit Drugs; Substance Abuse Detection; Substance-

2014
Cholesterol and CSF 5-HIAA in attempted suicide.
    Journal of affective disorders, 2010, Volume: 125, Issue:1-3

    Topics: Adjustment Disorders; Adolescent; Adult; Age Factors; Aged; Alcoholism; Anxiety Disorders; Bipolar D

2010
Neurochemical consequence of steroid abuse: stanozolol-induced monoaminergic changes.
    Steroids, 2012, Volume: 77, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Depression; Dopamine; Hippocampus; Homovan

2012
Reduction of group II metabotropic glutamate receptors during development of benzodiazepine dependence.
    Pharmacology, 2013, Volume: 91, Issue:3-4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzodiazepines; Cerebral Cortex; Dopamine; Flumazenil; GAB

2013
New evidence for an association between the CSF HVA:5-HIAA ratio and psychopathic traits.
    Journal of neurology, neurosurgery, and psychiatry, 2003, Volume: 74, Issue:7

    Topics: Adolescent; Adult; Age of Onset; Aggression; Antisocial Personality Disorder; Attention Deficit Diso

2003
Preexposure to MDMA ("Ecstasy") delays acquisition but facilitates MDMA-induced reinstatement of amphetamine self-administration behavior in rats.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Dextroamphetamine; Drug Interactions; Extinction, Psychological; H

2004
A slow-onset, long-duration indanamine monoamine reuptake inhibitor as a potential maintenance pharmacotherapy for psychostimulant abuse: effects in laboratory rat models relating to addiction.
    Neuropharmacology, 2006, Volume: 51, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dialysis;

2006
[A case of tranylcypromine and trifluoperazine (Jatrosom) addiction: psychopathological, sleep physiology and biochemical investigations].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1967, Volume: 210, Issue:2

    Topics: Adolescent; Adult; Benzoates; Catechols; Child; Child, Preschool; Depression; Dreams; Electroencepha

1967
Acute and chronic effects of pentobarbital on 5-hydroxytryptamine in mouse brain.
    Progress in neuro-psychopharmacology, 1981, Volume: 5, Issue:4

    Topics: Animals; Brain; Dopamine; Drug Tolerance; Fenclonine; Humans; Hydroxyindoleacetic Acid; Kinetics; Ma

1981
Formation of physical dependence on barbiturates and cerebral monoamines.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:2

    Topics: alpha-Methyltyrosine; Animals; Barbital; Barbiturates; Biogenic Amines; Body Weight; Brain; Catechol

1983
Neuropeptide FF potentiates the behavioral sensitization to amphetamine and alters the levels of neurotransmitters in the medial prefrontal cortex.
    Brain research, 1999, Jan-16, Volume: 816, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Dopamine; Drug Synergism; Hippocampus; Homovan

1999
Striatal serotonin is depleted in brain of a human MDMA (Ecstasy) user.
    Neurology, 2000, Jul-25, Volume: 55, Issue:2

    Topics: Adult; Brain Mapping; Corpus Striatum; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Male; N-M

2000
Changes in serotonin, dopamine and noradrenaline levels in striatum and nucleus accumbens after repeated administration of the abused drug MDMA in rats.
    Neuroscience letters, 2001, Aug-03, Volume: 308, Issue:2

    Topics: Animals; Axons; Dopamine; Drug Administration Schedule; Hallucinogens; Hydroxyindoleacetic Acid; Mal

2001
Increased rate of disappearance of serum probenecid in barbital dependent rats.
    European journal of pharmacology, 1976, Volume: 40, Issue:2

    Topics: Animals; Barbiturates; Humans; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Substance-Related D

1976
Assessment of dopamine release by in vivo microdialysis in the nucleus accumbens of rats following acute and chronic administration of desipramine.
    Annals of the New York Academy of Sciences, 1992, Jun-28, Volume: 654

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Desipramine; Dialysis; Dopamine; Homovanillic Acid; Hydroxy

1992
Aminergic metabolites in cerebrospinal fluid of humans previously exposed to MDMA: preliminary observations.
    Annals of the New York Academy of Sciences, 1990, Volume: 600

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Biogenic Amines; Designer Drugs; Female; Homovanillic Acid; Hu

1990
Dopaminergic activity is reduced in the prefrontal cortex and increased in the nucleus accumbens of rats predisposed to develop amphetamine self-administration.
    Brain research, 1991, Dec-13, Volume: 567, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Hy

1991
Dementias, psychological tests, and neurotransmitters.
    Archives of gerontology and geriatrics, 1985, Volume: 4, Issue:4

    Topics: Aged; Alcoholism; Alzheimer Disease; Dementia; Diagnosis, Differential; Female; Homovanillic Acid; H

1985
The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    The New England journal of medicine, 1985, May-30, Volume: 312, Issue:22

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Corpus Striatum; Dopamine; Female; Homovanillic

1985
The effect of parachlorophenylalanine on the sleep of a methadone addict.
    The British journal of psychiatry : the journal of mental science, 1973, Volume: 122, Issue:567

    Topics: Action Potentials; Adult; Electroencephalography; Electromyography; Electrooculography; Fenclonine;

1973
5-Hydroxytryptamine and 5-hydroxyindolylacetic acid content in brain of rat strains selected for their alcohol intake.
    Physiology & behavior, 1972, Volume: 8, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Animals; Body Temperature; Brain; Brain Chemistry; Disease Models, Ani

1972
Urinary excretion of monoamines and metabolites in patients dependent on and withdrawn from barbiturates.
    Psychopharmacologia, 1973, May-21, Volume: 30, Issue:2

    Topics: Barbiturates; Catecholamines; Dopamine; Epinephrine; Female; Homovanillic Acid; Humans; Hydroxyindol

1973
Acid monoamine metabolites in cerebrospinal fluid during methadone maintenance.
    Nature, 1971, Aug-20, Volume: 232, Issue:5312

    Topics: Adult; Female; Heroin; Humans; Hydroxyindoleacetic Acid; Male; Methadone; Middle Aged; Phenylacetate

1971
Metabolites of monoamines in urine and cerebrospinal fluid, after large dose amphetamine administration.
    Psychopharmacologia, 1972, Volume: 26, Issue:1

    Topics: Amines; Amphetamine; Glycols; Humans; Hydroxyindoleacetic Acid; Male; Perceptual Disorders; Phenylac

1972
Acute psychosis induced by psychotomimetic drug abuse. II. Neurochemical findings.
    Archives of general psychiatry, 1972, Volume: 27, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Animals; Brain Chemistry; Female; Hallucinogens; Humans; Hydroxyin

1972
Cigarette dependence.
    British medical journal, 1971, Jul-10, Volume: 3, Issue:5766

    Topics: Acetates; Epinephrine; Histamine; Humans; Hydroxyindoleacetic Acid; Imidazoles; Nicotine; Norepineph

1971
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